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2021-07-27_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated twice a week on Tuesdays and Fridays.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, …

Metabolic Modeling And Omics-Integrative Analysis Of Single And Multi-Organism Systems: Discovery And Redesign, Mohammad Mazharul Islam

Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research

Computations and modeling have emerged as indispensable tools that drive the process of understanding, discovery, and redesign of biological systems. With the accelerating pace of genome sequencing and annotation information generation, the development of computational pipelines for the rapid reconstruction of high-quality genome-scale metabolic networks has received significant attention. These models provide a rich tapestry for computational tools to quantitatively assess the metabolic phenotypes for various systems-level studies and to develop engineering interventions at the DNA, RNA, or enzymatic level by careful tuning in the biophysical modeling frameworks. in silico genome-scale metabolic modeling algorithms based on the concept of optimization, …

Alma Link Resolver Title & Issn Report (Top 500) 2020-2021, Andrée J. Rathemacher

Technical Services Reports and Statistics

Statistics for 2020-2021 on the total number of OpenURL requests by journal title and ISSN made to the Ex Libris Alma link resolver for items held by the University of Rhode Island Libraries. Includes only the top 500 journals.

Information provided includes journal Title, ISSN, EISSN, Number of Requests, Number of Clicked Requests, % Clicks from Requests.

Post-Acute Sequelae Of Covid-19 (Pasc): Association With Inflammation And Autoimmunity, Raghava S. Ambadapoodi, Fnu Deepti, Javaria Anwer Mbbs, Rafael Fernandez-Botran

The University of Louisville Journal of Respiratory Infections

It has become increasingly evident that a high percentage of patients that recover from acute COVID-19 infection continue to suffer from a variety of persistent symptoms even months after viral clearance, the most common ones being fatigue, dyspnea, anosmia, dysgeusia, cognitive dysfunction, and psychological problems, including anxiety and depression. This syndrome, known as Post-acute sequelae of COVID-19 (PASC), can severely affect the life quality and represents an important health care concern. The exact causes for the symptoms observed in patients with PASC remain to be adequately characterized, but are likely to be associated with multiple factors, including residual disease and/or …

Research News, Publications, 2021, Volume 2, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period of April 1 through June 30, 2021

2021 Summer Experience Program Abstracts, The University Of Texas Md Anderson Cancer Center

Summer Experience 2021

The mission of the MD Anderson Summer Experience Program is to eliminate cancer, through training of high School, undergraduates and first year medical students to make a lasting impact on training the next generation of scientist and physicians through research and education.

The MD Anderson Summer Experience is an umbrella program that comprises 18 summer academic programs at MD Anderson.

The summer research program is an 8-10 week program that offers hands-on experience in biomedical, translational or clinical research. In this program, students are matched with a mentor from MD Anderson’s research or clinical faculty. Participants work alongside the mentor …

Informing Policy On Built Environments To Safeguard Children In Environmental Justice Communities: Case Study Of Five Aap Climate Advocates, Katie Durrwachter-Erno Md, Gredia Huerta-Montanez Md, Vivian Nguyen, Aaron A. Levy Do, Jennifer M. Lawson Md, Vi T. Nguyen Md

Journal of Applied Research on Children: Informing Policy for Children at Risk

Climate change’s health effects are most strongly felt in Environmental Justice (EJ) communities which are predominantly people of color. This results in a disproportionate burden of climate change health effects on EJ communities. Climate change is a public health crisis, and more importantly to pediatricians – it is a pediatric public health crisis. We are five pediatricians who are part of the American Academy of Pediatrics (AAP) Climate Advocate Program representing four diverse regions; Colorado, California, Puerto Rico, and North Carolina. We are applied research practitioners, as we live in the world between academic research and clinical practice. We are …

Bcr Affinity Influences T-B Interactions And B Cell Development In Secondary Lymphoid Organs, Alec J. Wishnie, Tzippora Chwat-Edelstein, Mary Attaway, Bao Q. Vuong

Publications and Research

B cells produce high-affinity immunoglobulins (Igs), or antibodies, to eliminate foreign pathogens. Mature, naïve B cells expressing an antigen-specific cell surface Ig, or B cell receptor (BCR), are directed toward either an extrafollicular (EF) or germinal center (GC) response upon antigen binding. B cell interactions with CD4+ pre-T follicular helper (pre- Tfh) cells at the T-B border and effector Tfh cells in the B cell follicle and GC control B cell development in response to antigen. Here, we review recent studies demonstrating the role of B cell receptor (BCR) affinity in modulating T-B interactions and the subsequent differentiation of B …

Risk Factors And Outcomes Associated With Community-Onset And Hospital-Acquired Coinfection In Patients Hospitalized For Coronavirus Disease 2019 (Covid-19): A Multihospital Cohort Study, Lindsay A. Petty, Scott A. Flanders, Valerie M. Vaughn, David Ratz, Megan O'Malley, Anurag N. Malani, Laraine Washer, Tae Kim, Keith E. Kocher, Scott Kaatz, Tawny Czilok, Elizabeth Mclaughlin, Hallie C. Prescott, Vineet Chopra, Tejal Gandhi

Hospital Medicine Articles

BACKGROUND: We sought to determine the incidence of community-onset and hospital-acquired coinfection in patients hospitalized with coronavirus disease 2019 (COVID-19) and to evaluate associated predictors and outcomes.

METHODS: In this multicenter retrospective cohort study of patients hospitalized for COVID-19 from March 2020 to August 2020 across 38 Michigan hospitals, we assessed prevalence, predictors, and outcomes of community-onset and hospital-acquired coinfections. In-hospital and 60-day mortality, readmission, discharge to long-term care facility (LTCF), and mechanical ventilation duration were assessed for patients with versus without coinfection.

RESULTS: Of 2,205 patients with COVID-19, 141 (6.4%) had a coinfection: 3.0% community onset and 3.4% hospital …

Back To School: A Complete Health Checklist For Parents, Staff

Browse All News

No abstract provided.

Intensive Hunting Pressure Changes Local Distribution Of Wild Boar, Jakub Drimaj, Jiří Kamler, Radim Plhal, Přemysl Janata, Zdeněk Adamec, Miloslav Homolka

Human–Wildlife Interactions

Wild boar (Sus scrofa) is now an important species of wild ungulates in Central Europe. Next to conflicts of wild boar with agriculture, the main threat of wild boar presence lies in the expansion of African swine fever across Europe. The regulation of the wild boar population is complicated by the high reproduction rate and intelligent behavior of the species, which limits hunting effectiveness. We analyzed the spatial behavior of wild boar in an environment with a lack of natural food resources. The study area consisted of a forest complex (1,283 ha) with 2 areas. In the “risk” …

Acute Encephalitis, Myoclonus And Sweet Syndrome After Mrna-1273 Vaccine, Gabriel Torrealba-Acosta, Jennifer C Martin, Yve Huttenbach, Catherine R Garcia, Muhammad R Sohail, Sandeep Krishna Agarwal, Carina Wasko, Eric M Bershad, Mohammad I Hirzallah

Faculty, Staff and Students Publications

A patient presented with fever, generalised rash, confusion, orofacial movements and myoclonus after receiving the first dose of mRNA-1273 vaccine from Moderna. MRI was unremarkable while cerebrospinal fluid showed leucocytosis with lymphocyte predominance and hyperproteinorrachia. The skin evidenced red, non-scaly, oedematous papules coalescing into plaques with scattered non-follicular pustules. Skin biopsy was consistent with a neutrophilic dermatosis. The patient fulfilled the criteria for Sweet syndrome. A thorough evaluation ruled out alternative infectious, autoimmune or malignant aetiologies, and all manifestations resolved with glucocorticoids. While we cannot prove causality, there was a temporal correlation between the vaccination and the clinical findings.

Humoral Immune Responses During Sars-Cov-2 Mrna Vaccine Administration In Seropositive And Seronegative Individuals., Elizabeth Fraley, Cas Lemaster, Eric S. Geanes, Dithi Banerjee, Santosh Khanal, Elin Grundberg, Rangaraj Selvarangan, Todd Bradley

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: The global pandemic of coronavirus disease 2019 (COVID-19) is caused by infection with the SARS-CoV-2 virus. Currently, there are three approved vaccines against SARS-CoV-2 in the USA, including two based on messenger RNA (mRNA) technology that has demonstrated high vaccine efficacy. We sought to characterize humoral immune responses, at high resolution, during immunization with the BNT162b2 (Pfizer-BioNTech) vaccine in individuals with or without prior history of natural SARS-CoV-2 infection.

METHODS: We determined antibody responses after each dose of the BNT162b2 SARS-CoV-2 vaccine in individuals who had no prior history of SARS-CoV-2 infection (seronegative) and individuals that had previous viral …

Clinical Features And Outcomes Of Critically Ill Patients With Elizabethkingia Meningoseptica: An Emerging Pathogen, Abdullah Umair, Nosheen Nasir

Department of Medicine

Background: Elizabethkingia meningoseptica, formerly known as Chryseobacterium meningosepticum, is a non-motile, non-fastidious, catalase and oxidase-positive, aerobic, glucose-non-fermentative, Gram-negative bacillus that was first defined by Elizabeth O. King in 1959. It has emerged as an opportunistic pathogen that has infected patients in extreme age groups and immunocompromised individuals, especially in intensive care settings. There has been an increased interest in this pathogen due to its increasing occurrence around the world, ubiquitous nature, and inherent capacity for antimicrobial resistance.
Methods: We describe an observational study at a tertiary care center in Karachi, Pakistan, based on patients admitted between January 2013 and December …

Establishing Peer Recovery Support Services To Address The Central Appalachian Opioid Epidemic: The West Virginia Peers Enhancing Education, Recovery, And Survival (Wv Peers) Pilot Program, Stephen M. Davis, Amanda Stover, Herb Linn, Jon Dower, Dan Mccawley, Erin Winstanley, Judith Feinberg

Journal of Appalachian Health

Introduction: Central Appalachia has been disproportionately affected by the opioid epidemic and overdose fatalities. We developed West Virginia Peers Enhancing Education, Recovery, and Survival (WV PEERS), a program based on peer recovery support, to engage individuals using opioids and link them with a range of services.

Methods: Community partners providing services to individuals with opioid use disorder (OUD) were identified and collaborations were formalized using a standardized memorandum of understanding. The program was structured to offer ongoing peer recovery support specialist (PRSS) services, not just a one-time referral. A website and cards describing the WV PEERS program were developed and …

Periodontal Microbiome Part I: A Literature Review, Carole Chakar, Gabriel Menassa, Roudy Khayat

International Arab Journal of Dentistry

Periodontal disease is one of the most chronic infectious diseases, it is initiated by a reversible inflammatory condition called gingivitis, if untreated, it progresses to an irreversible condition called periodontitis, if not resolved, it leads to tooth loss. Periodontitis is a multifactorial disease, one of these factors is the periodontal microbiome. Consequently, the microbiome is altered according to the host state i.e., health, gingivitis, periodontitis. The microbiome in health is comprised of a variety of microorganisms called health-associated species. They consist of gram-positive cocci and rod with gram-negative species. In this state, the microbiome participates in various physiological functions. While …

2021-07-24_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated twice a week on Tuesdays and Fridays.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, …

Influence Of Sult1a1*2 Polymorphism On Plasma Efavirenz Concentration In Thai Hiv-1 Patients, Monpat Chamnanphon, Rattanaporn Sukprasong, Andrea Gaedigk, Weerawat Manosuthi, Pajaree Chariyavilaskul, Supeecha Wittayalertpanya, Napatrupron Koomdee, Thawinee Jantararoungtong, Apichaya Puangpetch, Chonlaphat Sukasem

Manuscripts, Articles, Book Chapters and Other Papers

Purpose: Plasma efavirenz (EFV) concentrations within therapeutic levels are essential to successfully treat patients suffering from human immunodeficiency virus (HIV) type 1. In addition to the drug-metabolizing enzyme CYP2B6, other phase II drug-metabolizing enzymes and transporters may have an important role in the pharmacokinetics of EFV. Thus, the influence of phase II drug-metabolizing enzymes and drug transporters on plasma EFV levels was investigated in Thai HIV patients receiving EFV.

Patients and methods: Genotyping was performed by TaqMan® real-time PCR in 149 HIV-infected Thai adults, and plasma efavirenz concentration was measured by a validated high-performance liquid chromatography in 12 hours after …

Acceptance Of Covid-19 Vaccine In Pakistan: A Nationwide Cross-Sectional Study, Mohammad Aadil Qamar, Omar Irfan, Rubaid A. Dhillon, Areesh Bhatti, Mir Ibrahim Sajid, Safia Awan, Wajiha Rizwan, Ali Bin Sarwar Zubairi, Zouina Sarfraz, Javaid Ahmed Khan

Department of Paediatrics and Child Health

Introduction: The coronavirus disease 2019 (COVID-19) vaccine is available across various countries worldwide, with public-private partnerships ensuring all individuals are vaccinated through a phased approach. Irrespective of the geographical spread, several myths pertaining to the COVID-19 vaccine have stemmed, ultimately limiting the national administration of vaccines and rollouts. This study assessed the acceptance of the COVID-19 vaccine among the general public in Pakistan.
Methods: A pre-validated questionnaire was administered from January 2021 to February 2021 to assess the public attitude and acceptance of the COVID-19 vaccine. Logistic regression analyses were run to identify factors associated with the acceptance among the …

Dynamical Variations Of The Global Covid-19 Pandemic Based On A Seicr Disease Model: A New Approach Of Yi Hua Jie Mu, Xia Wang, Gang Yin, Zengyun Hu, Daihai He, Qianqian Cui, Xiaomei Feng, Zhidong Teng, Qi Hu, Jiansen Li, Qiming Zhou

Department of Earth and Atmospheric Sciences: Faculty Publications

The ongoing coronavirus disease 2019 (COVID-19) pandemic has caused more than 150 million cases of infection to date and poses a serious threat to global public health. In this study, global COVID-19 data were used to examine the dynamical variations from the perspectives of immunity and contact of 84 countries across the five climate regions: tropical, arid, temperate, and cold. A new approach named Yi Hua Jie Mu is proposed to obtain the transmission rates based on the COVID-19 data between the countries with the same climate region over the Northern Hemisphere and Southern Hemisphere. Our results suggest that the …

Real-World Applications For Analytics Teaching And Learning, Anita Lee-Post

Marketing & Supply Chain Textbook Gallery

This document provides learning-by-doing materials for Analytics software skill development using SAS JMP. It integrates Analytics concepts and techniques with real-world scenarios based on the COVID-19 pandemic to illustrate how real-world data can be transformed into actionable insights to offer decision support for COVID-19 related issues. A holistic treatment of the Analytics process from data acquisition and cleansing to data analysis and interpretation is emphasized using five studies:

1. Characterize COVID-19 mortality demographic risk factors,
2. Visualize COVID-19 mortality demographics,
3. Conduct COVID-19 mortality time series forecasting,
4. Predict COVID-19 mortality, and
5. Analyze COVID-19 vaccine acceptance, uptake, and experiences.

Each study is structured with …

Disease, Development, And Disorder: Examining The Effect Of Health On Subnational Development And Conflict In Sub-Saharan Africa, Dlorah C. Jenkins

Doctor of International Conflict Management Dissertations

Progress towards achieving the Sustainable Development Goals (SDGs) has been uneven across and within countries - particularly in Africa, least developed countries, and low-income countries. The COVID-19 pandemic has threatened to reverse much of the progress made towards achieving the SDGs, especially SDG 3, which aims to “ensure healthy lives and promote well-being for all at all ages”.

The tendency for disease, underdevelopment, and conflict to occur concomitantly suggests potential causal mechanisms linking them. This study attempts to address two pieces of the puzzle: the causal effect of disease on underdevelopment and the impact of development on conflict risk. Focusing …

July 23, 2021 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

The Relation Of Abo Blood Group To The Severity Of Coronavirus Disease: A Cross-Sectional Study From A Tertiary Care Hospital In Karachi, Fazal Ur Rehman, Syed Furrukh Omair, Fatima Memon, Bakhtawar J. Rind, Danish Ahmed Memon, Syed Ahsan Ali, Bilal Ahmed, Naureen Ali

Section of Internal Medicine

Background: Blood groups are considered to have an impact on the occurrence and severity of coronavirus disease. While among Chinese and Caucasian, blood group O individuals were less and group A were more likely to have severe disease and mortality, data on South Asians aren’t available.
Objective: This study aimed to find out the association of disease severity with blood group among coronavirus disease 2019 (COVID-19) patients.
Materials and methodology: Data were collected on a predesigned questionnaire containing details of patient demographics, medical comorbidities, clinical presentation, and laboratory parameters. Multiple logistic regression was used to determine the association of the …

Knowing Our People To Serve Our People, Alessandra Jimenez

MEDI 9331 Scholarly Activities Clinical Years

Health disparities continue to persist in the United States despite the work clinicians and professionals have undertaken to close the gaps. Nowhere in the recent past have these disparities been more evident than during the US response to the COVID-19 pandemic. The differential outcome of patients was stark within marginalized communities accounting for greater burden due to the health risks that were already incurred. Additionally, data provided from the health care system’s front lines were incomplete resulting in slower and less robust interventions than what were needed. This paper seeks to outline first steps that can be taken to ensure …

Informing Viral Surveillance Of Oropouche Virus: An Emerging Arbovirus, Christine E. Walsh

LSU Master's Theses

Arboviruses are viruses transmitted by hematophagous arthropod vectors. Many of these viruses pose a threat to human health. While some infections may be asymptomatic, others may produce febrile illness, or manifest in life threatening conditions. Symptomatic diagnosis of patients with generalized febrile illness can be confounded due to the various diseases that present clinically in the same manner, and a lack of available diagnostic tests. Surveillance efforts can be used to create awareness about the prevalence of neglected tropical arthropod-borne pathogens, such as Oropouche virus (OROV), and inform preparedness measures for disease outbreaks (SURVEILLANCE SENTENCE). OROV is an arbovirus and …

Medical School Watercooler Newsletter - July 22, 2021, Lindsey Lyle

Watercooler Newsletter

This is the July 22, 2021 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents include:

• Faculty Spotlight: Walker Plash, M.D.
• Student-Run Free Clinic seeks volunteer preceptors
• USA COM graduate researcher examines relationship between bacteria and their vectors
• Meet a Med Student: Alana Fortune

Vol.49 N.01 July 22nd 2021, Voice Media Ventures

Black Voice News

No abstract provided.

Uab Launches Series Of Informational Covid-19 Discussions For Medical Professionals And The Public, Alicia Rohan

Browse All News

No abstract provided.

2021-July-22-Etsu Recruiting Participants For Covid-19 Long Haulers Research, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY (July 22, 2021) – To learn more about the long-term effects of the COVID-19 virus, researchers at East Tennessee State University are seeking research participants who have been diagnosed with COVID-19 and who have continued to experience ongoing effects 90 days after recovery.

Individuals who experience lingering symptoms from the virus often describe themselves as COVID-19 “long haulers.”

 “New evidence suggests that COVID-19 negatively impacts various body systems, both during time of infection, and in some, for weeks to months after recovery,” said James L. Adkins, clinical research coordinator for ETSU’s Center of Excellence in Inflammation, Infectious Disease …