Digital Commons Network^™

Effects Of Drying, Packaging Conditions And Storage Time On Proximate Composition Of Chia Seeds (Salvia Hispanica), Ashura Katunzi-Kilewela, Leonard Rweyemamu, Oscar Kibazohi, Lilian Kaale

Tanzania Journal of Science

The effects of drying, packaging conditions and storage time on proximate composition of chia seeds were investigated. Chia seeds were dried at 63 °C for 30 min (low-temperature long time–LTLT) and at 75 °C for 30 s (high-temperature short time-HTST) using dry oven, air/vacuum-packed and stored for ten weeks. The effect of heat processing (drying) on chia seeds had significant difference (p < 0.05) in ash, fiber and fat contents while there was no significant difference (p > 0.05) in moisture and protein contents. Except for fiber content, there was no significant difference (p > 0.05) in moisture, ash, fat and protein of chia seeds dried at LTLT and HTST before storage. During storage time, there was …

Establishing A Mechanistic Link Between Disturbed Flow And Aneurysm Formation In A 3d Cerebral Bifurcation Model, Nesrine Bouhrira

Theses and Dissertations

The effect of disturbed flow profiles on the endothelium have been studied extensively in systemic vasculature, but less is known about the response of the blood-brain barrier (BBB) to these flow regimes. Here we investigate the effect of steady and pulsatile disturbed flow on the integrity of the BBB using a three-dimensional, perfusable bifurcation model consisting of a co-culture of endothelial cells with mural and glial cells. Experimental flow patterns predicted by computational fluid dynamics mimic in vivo flow regimes, specifically the presence of a recirculation zone immediately downstream of the bifurcation reveal periodic changes in the instantaneous shear stress …

Aacp Basic Resources For Pharmacy Education, Jason Guy, Ivan Portillo, Robert D. Beckett, Kayce Gill, Kimberly Mitchell, Jill Nissen, Priya Shenoy

Library Association/Organization Work

"The AACP Basic Resources for Pharmacy Education is produced as a guide for those developing or maintaining the library collections that serve colleges and schools of pharmacy. The goal of the Basic Resources list is to make recommendations of books and other works to be included in pharmacy libraries, but not all titles are required to be purchased. Each pharmacy college has its own mission and its own program(s), and so each college’s library collection must reflect that mission and support the college’s program(s). Excellent library collections are built by knowledgeable librarians and drug information specialists using their professional judgment …

Applying Spatial Video Geonarratives And Physiological Measurements To Explore Perceived Safety In Baton Rouge, Louisiana, Alina Ristea, Michael Leitner, Bernd Resch, Judith Stratmann

Faculty Publications

Spatial crime analysis, together with perceived (crime) safety analysis have tremendously benefitted from Geographic Information Science (GISc) and the application of geospatial technology. This research study discusses a novel methodological approach to document the use of emerg-ing geospatial technologies to explore perceived urban safety from the lenses of fear of crime or crime perception in the city of Baton Rouge, USA. The mixed techniques include a survey, spatial video geonarrative (SVG) in the field with study participants, and the extraction of moments of stress (MOS) from biosensing wristbands. This study enrolled 46 participants who completed geonarratives and MOS detection. A …

A Timely Call To Arms: Covid-19, The Circadian Clock, And Critical Care, Jeffrey Haspel, Minjee Kim, Phyllis Zee, Tanja Schwarzmeier, Sara Montagnese, Satchidananda Panda, Adriana Albani, Martha Merrow

2020-Current year OA Pubs

We currently find ourselves in the midst of a global coronavirus disease 2019 (COVID-19) pandemic, caused by the highly infectious novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we discuss aspects of SARS-CoV-2 biology and pathology and how these might interact with the circadian clock of the host. We further focus on the severe manifestation of the illness, leading to hospitalization in an intensive care unit. The most common severe complications of COVID-19 relate to clock-regulated human physiology. We speculate on how the pandemic might be used to gain insights on the circadian clock but, more importantly, on …

Ground Reaction Forces And Temporal Characteristics Define Cutting Performance, Matthew L. Welinski, Lindsey N. Lee, Blake Mcbroom, Bassel Mufarreh, Lex Gidley

International Journal of Exercise Science

International Journal of Exercise Science 14(1): 211-221, 2021. Moderate angle cutting maneuvers (between 45º and 90º) are common and essential performance skills for success in multidirectional sports. Research addresses the injury risks of cutting but few studies have attempted to quantify the performance of the cut itself. PURPOSE: To identify any anthropometric, kinematic, and/or kinetic markers of a high-performance cut so they may be taught and lead to more effective training. METHODS: Ten college-aged male athletes (mass 73.97 ± 8.77kg, height 1.81 ± 0.07m) and ten non-athletes (mass 87.37 ± 13.93kg, height 1.85 ± 0.04m) completed five moderate angle cutting …

The Effect Of The Difference In The Perception Of Temperature Between Sexes On The Academic Performance Of Chapin High School Students, Tiffany V. Phan

Journal of the South Carolina Academy of Science

Mental performance and mental functions may be negatively affected by decreases in thermal comfort as a result of large differences in temperature. Additionally, females are seen to be less content with room temperatures and actually prefer rooms with higher temperatures in comparison to males. This investigation explored the potential effect that sex plays in thermal perception and the impact it may yield on academic performance within a high school population. It was hypothesized that female students would experience an increase in academic performance as the temperature increased while males would experience the opposite effect. A quasi-experimental approach was used to …

Experimental Pharmacotherapies In Models Of Alcohol Addiction, Mousumi Akter Sumi

Theses and Dissertations

The USA faces $220 billion economic loss and eighty thousand deaths per year due to alcohol abuse while affecting more than 15 million people, making it the third largest life-style related cause of death. The U.S. FDA has approved four medications namely, disulfiram, acamprosate, oral naltrexone, and injectable long-acting naltrexone. These existing drugs are trashed with side effects, have a low success rate, indicating a demand for new potential drugs. We studied the effects of the CB1 negative allosteric modulator, PSNCBAM-1, and the dopamine D4 receptor antagonist, L-745,870 in mouse models of alcohol addiction. PSNCBAM-1 did not significantly reduce CPP …

Overstraining Human Nature In The Nicomachean Ethics, Douglass Reed

Philosophy Faculty Publications

In this paper, I investigate Aristotle’s claim in Nicomachean Ethics III.1 about situations that “overstrain human nature.” By setting out and answering several interpretative questions about such situations, I offer a comprehensive interpretation of this passage. I argue that in (at least some of) these cases, the agent voluntarily does something wrong, even though there is a right action available. Furthermore, I argue that Aristotle would think it is possible for a rare agent to perform the right action in (at least some of) these cases, overcoming the limitations of human nature by identifying with the divine part of the …

Knowledge Network Embedding Of Transcriptomic Data From Spaceflown Mice Uncovers Signs And Symptoms Associated With Terrestrial Diseases, Amber M. Paul, Charlotte A. Nelson, Ana Uriarte Acuna, Ryan T. Scott, Atul J. Butte, Egle Cekanaviciute, Sergio E. Baranzini

Publications

There has long been an interest in understanding how the hazards from spaceflight may trigger or exacerbate human diseases. With the goal of advancing our knowledge on physiological changes during space travel, NASA GeneLab provides an open-source repository of multi-omics data from real and simulated spaceflight studies. Alone, this data enables identification of biological changes during spaceflight, but cannot infer how that may impact an astronaut at the phenotypic level. To bridge this gap, Scalable Precision Medicine Oriented Knowledge Engine (SPOKE), a heterogeneous knowledge graph connecting biological and clinical data from over 30 databases, was used in combination with GeneLab …

Central Washington University 2021-2022 Graduate Catalog, Central Washington University

Course Catalogs

No abstract provided.

The Impact Of Visual Literacy In Secondary Science Education, Elise M. Miller

All Electronic Theses and Dissertations

Visual literacy, or the ability to make sense of and produce images, is an essential but long underrated skill in science. Career scientists and engineers decode and encode information in pictorial form using visual literacy skills regularly. This research will explore first the purpose of science education in the United States and how its reforms have been influenced by career scientists. It will explore if visual literacy skills are aligned with these purposes. This research will then investigate the benefits of incorporating visual literacy in science education to this end. Finally, this research will outline research-based instructional strategies for integrating …

Role Of Na/K-Atpase Non-Enzymatic Signaling In Renal Proximal Tubule Sodium Transport, Shreya Tapan Mukherji

Theses, Dissertations and Capstones

The renal proximal tubule (RPT) is the center stage for renal handling of Na+ , a potent determinant of systemic Na+ and volume homeostasis in health and disease. In the RPT, through its classic ion-pumping function, Na + /K+ -ATPase (NKA) generates the Na+ gradient that drives apical Na+ absorption, mostly through Na+ /H+ exchanger (NHE3). In contrast, pharmacological evidence suggests that the activation of the NKA non-enzymatic signaling function, through Src and other signaling partners, triggers a cellular redistribution of NKA and NHE3 that decreases transcellular Na+ flux in cultured RPT cells. However, the physiological relevance of the nonenzymatic …

The Effects Of Endocrine Disrupting Chemicals On Plants, Christian Mathew Pridemore

Theses, Dissertations and Capstones

Endocrine disrupting chemicals (EDCs) are a diverse group of chemicals which can have a detrimental effect on human health, affecting any physiological body system sensitive to hormonal changes. Human exposure to EDCs is inevitable due to their prevalence in modern living; EDCs are integral compounds found in everyday items with which humans interact and ingest. These, along with other indirect avenues leading to EDC exposure, pose a threat to both human health and to the health of wildlife and agricultural environments. Studies on the effects of EDCs on plants can be substantially informative and necessary for progress towards solving the …

Taylor University Catalog 2021-2022, Taylor University

Undergraduate Catalogs

The 2021-2022 academic catalog of Taylor University in Upland, Indiana.

Physician Assistant_Fort Lauderdale_2021, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Approved General Education (Ge) Distribution Courses, Kean University

Evidence Inventory

General Education Program's List of Approved Distribution Courses

A Review Of Contemporary Techniques For Measuring Ergonomic Wear Comfort Of Protective And Sport Clothing, Yetanawork Teyeme, Benny Malengier, Tamrat Tesfaye, Izabela Ciesielska-Wrobel, Atiyyah Binti Haji Musa, Lieva Van Langenhove

Textiles, Fashion Merchandising and Design Faculty Publications

Protective and sport clothing is governed by protection requirements, performance, and comfort of the user. The comfort and impact performance of protective and sport clothing are typically subjectively measured, and this is a multifactorial and dynamic process. The aim of this review paper is to review the contemporary methodologies and approaches for measuring ergonomic wear comfort, including objective and subjective techniques. Special emphasis is given to the discussion of different methods, such as objective techniques, subjective techniques, and a combination of techniques, as well as a new biomechanical approach called modeling of skin. Literature indicates that there are four main …

Adaptive Two-Stage Edge-Centric Architecture For Deeply-Learned Embedded Real-Time Target Classification In Aerospace Sense-And-Avoidance Applications, Nicholas A. Speranza

Browse all Theses and Dissertations

With the growing number of Unmanned Aircraft Systems, current network-centric architectures present limitations in meeting real-time and time-critical requirements. Current methods utilizing centralized off-platform processing have inherent energy inefficiencies, scalability challenges, performance concerns, and cyber vulnerabilities. In this dissertation, an adaptive, two-stage, energy-efficient, edge-centric architecture is proposed to address these limitations. A novel, edge-centric Sense-and-Avoidance architecture framework is presented, and a corresponding prototype is developed using commercial hardware to validate the proposed architecture. Instead of a network-centric approach, processing is distributed at the logical edge of the sensors, and organized as Detection and Classification Subsystems. Classical machine vision algorithms are …

Anatomy Master's Degree Annual Program Outcomes Assessments, 2020-21, College Of Science And Mathematics, Wright State University

Annual Program Outcomes Assessments - All

This report reviews Wright State University's Anatomy Master's Degree program for the 2020-2021 academic year.

Characterization Of Clostridium Cochlearium As A Potential Probiotic For Obesity Management, Paba Edirisuriya

Wayne State University Dissertations

ABSTRACTCHARACTERIZATION OF CLOSTRIDIUM COCHLEARIUM AS A POTENTIAL PROBIOTIC FOR OBESITY MANAGEMENT

ByPABA EDIRISURIYA MAY 2021 Advisor: Dr. Kequan Zhou Major: Nutrition and food science Degree: Doctor of Philosophy Emerging evidence indicates that manipulation of gut microflora is a potential therapeutic approach for managing obesity. Probiotic effects on host weight reduction have repeatedly been revealed through previous studies. Clostridium cochlearium is a butyrate-producing, spore-forming bacteria that have been reported to present in the mammalian gut. Our simulated Invitro digestion model revealed that C. cochlearium could survive in the unfavorable conditions of the human gastrointestinal tract, including low pH (pH2), high bile …

The Role Of Nutrient Availability In Therapeutic Response Of Leukemia, Rohiverth Guarecuco Jr.

Student Theses and Dissertations

Tumor environment influences the response to anti-cancer therapy, but which extracellular nutrients impact drug sensitivity is largely unknown. In this work, we used functional genomics to identify metabolic modifiers of the response to L-asparaginase (ASNase), a therapy that depletes plasma asparagine and targets leukemic cells with insufficient asparagine synthesis. Our approach revealed thiamine pyrophosphate kinase 1 (TPK1), which converts vitamin B1 (thiamine) into the cofactor thiamine pyrophosphate (TPP), as a metabolic dependency under ASNase treatment. In glutamine-anaplerotic leukemia cells, we found that TPP availability enables asparagine synthesis from extracellular glutamine. Mechanistically, TPP is critical for the activity of alpha-ketoglutarate dehydrogenase …

Transcriptional Regulation Of The Metabolic Response To Therapy In Leukemia, Robert Thomas Williams

Student Theses and Dissertations

Cancer cells are under constant stress due to their uncontrolled growth, oncogenic signaling, and the metabolic insufficiencies of their microenvironments. Under various stresses, cells activate the integrated stress response (ISR), a transcriptional program to restore cellular homeostasis. Activating transcription factor 4 (ATF4) acts as the master transcriptional regulator of the ISR by promoting the transcription of genes that mitigate stress or promote cell death if the stress remains unresolved. Despite being the common mediator of various stress response and metabolic pathways, ATF4 generates tailored transcriptional outputs to distinct cellular stresses by cooperating with other transcriptional machinery. The precise mechanisms by …

Molecular Genetic Modifications In The Human Genome: Racial Discrimination As A Biological Stressor, Nicolette Dobson

UReCA: The NCHC Journal of Undergraduate Research and Creative Activity

Research titled Molecular Genetic Modifications in the Human Genome: Racial Discrimination as a Biological Stressor by Nicolette Dobson in UReCA: The NCHC Undergraduate Journal of Research and Creative Activity, 2021, pages 1-24.

Abstract

Racial discrimination enhances group separation and places individuals into stereotypical categories based on race and other factors (e.g. gender, behavior, etc.). As seen in studies on physiological diseases and psychological disorders, minority groups (e.g. African Americans) face cellular senescence at an increased risk due to health-related comorbidities and prevalent experiences of racism. This review provides an analysis of modifications within the human genome that may lead to …

News From Hope College Index, Hope College Archives And Special Collections

Newspaper Indexes

This index contains listings of articles in News from Hope College (1973–2014). News From Hope College is a newsletter put out by the college. It contains articles on students, alumni, events, issues, alumni listings, etc.

Gattonrx Magazine - 2021, Bill Gatton College Of Pharmacy, East Tennessee State University

GattonRX Magazine

No abstract provided.

The Influence Of Infant Formula On The Growth Of Commensal And Pathogenic Streptococcus Species In The Infant Oral Cavity, Geneva Waynick

Undergraduate Honors Theses

The oral microbiome is a complex community of microorganisms that can both reflect and greatly influence the health of the human host. A number of diseases are associated with dysbiotic oral microflora in infants and children, including dental (e.g. dental caries, gingivitis, and periodontal disease), and gastrointestinal diseases (e.g. pediatric appendicitis, celiac disease, and pediatric inflammatory bowel disease). A variety of factors can influence the composition of the oral microbial community in infants, including gestation length, mode of delivery, feeding method, and diet. This study focuses on the effects of diet on the growth of a commensal bacterium (Streptococcus …

Effect Of Remaining Dentin Thickness And Primer Application Technique On Microtensile Bond Strength, Paphawee Somrit

Chulalongkorn University Theses and Dissertations (Chula ETD)

To evaluate the effect of primer application techniques, type of adhesives and remaining dentin thicknesses on microtensile bond strength (µTBS) of 4 different adhesive systems, 112 Flat occlusal surfaces of sound third molar were randomly allocated into 16 groups based on 2 remaining dentin thicknesses (RDT), 2 application techniques and 3 adhesive systems, e.g., Three step etch-and-rinse (Optibond FL; OFL), Two step self-etch (Clearfil SE Bond; CSE), and Universal adhesive (Single Bond Universal; SB). SB was applied in either etch-and-rinse (ER) or self-etch (SE) mode. Simulated pulpal pressure was performed during bonding procedure and 6-month water storage (37 oC). After …

Impact Of Carcass Chilling System On Carcass Characteristics And Biochemical Changes In Beef Carcasses, Lydia Margaret Hite

Electronic Theses and Dissertations

Effective and efficient chilling of beef carcasses will directly influence meat quality and consumer acceptance. Over the past century the United States’ meat industry has evolved, and spray chilling system have become common practice utilized by the beef industry. However, many of the chilling systems presently in use were designed to chill carcasses averaging lighter than the average beef hot carcass weight of today. Beef hot carcass weight has increased 68 kilograms from 1991 to 2019. The increase in beef hot carcass weight could result in longer chilling periods and present possible challenges for chilling systems used by the beef …

The Morass Of Misconceptions: How Unjustified Beliefs Influence Pedagogy And Learning, Morgan Mcafee, Bobby Hoffman

International Journal for the Scholarship of Teaching & Learning

When teachers harbor misconceptions or unjustified beliefs about teaching, learning, and academic motivation, the pedagogical consequences can be severe. It is likely these teachers will unintentionally perpetuate such false beliefs upon students through ineffective teaching strategies or misinterpretations of learning science. Misconceptions among K-12 teachers are particularly deleterious due to the substantial influence teacher beliefs exert upon curriculum development, pedagogy, and the construction of effective learning environments. Prior research has explicated the prevalence of erroneous beliefs about general psychology and neuroscience among various populations but has rarely examined teachers’ misconceptions about pertinent topics in educational psychology. Consequently, this review highlights …