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2021

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Time Clustering In Microstructure, Neighborhood Blight In Real Estate, And Inter-Firm Connections In Corporate Alliances, Wei Sun Jan 2021

Time Clustering In Microstructure, Neighborhood Blight In Real Estate, And Inter-Firm Connections In Corporate Alliances, Wei Sun

Electronic Theses and Dissertations Archive

Essay 1: We introduce and analyze a new intraday measure of trade-time clustering which we demonstrate to be superior to volume and duration at detecting periodic grouping of trades. In stable markets, both elevated information flow and lower trading costs lead to greater trade-time clustering, while in volatile markets only lower trading costs lead to greater time clustering. Trade-time clustering is positively associated with contemporaneous price impact, price volatility, and negatively associated with variance ratios, suggesting that trade clustering contributes to price discovery. Following increased time clustering, we observe more aggressive orders from informed traders, but less HFT in stable …

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"I Didn't Feel Doctoral Worthy": Motivating Factors For Black Female, First-Generation Doctoral Students, Margaret Cole Taylor Jan 2021

"I Didn't Feel Doctoral Worthy": Motivating Factors For Black Female, First-Generation Doctoral Students, Margaret Cole Taylor

Electronic Theses and Dissertations Archive

This study examines the motivating factors for Black female, first-generation doctoral students. The critical problem I found was that little is known how Black female doctoral students persevere to completing their doctoral degrees. Therefore, this study sought to identify factors that influence first-generation Black females to pursue and complete a doctorate. I approached the study through the theoretical lens of Womanism. Womanism is defined as a theory based on Black womens lives experiences, works to change negative images of Black women, and restores a balance to the community through a lens of spirituality. In chapter 2, I identified the critical …

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Bridging Symtpoms In Ptsd And Suicidal Ideation: Disentangling Dysfunctional Cognitions And Emotions In The Ptsd Symptoms D2, D3, And D4, Han Tran Jan 2021

Bridging Symtpoms In Ptsd And Suicidal Ideation: Disentangling Dysfunctional Cognitions And Emotions In The Ptsd Symptoms D2, D3, And D4, Han Tran

Electronic Theses and Dissertations Archive

Specific PTSD symptoms, certain dysfunctional cognitions and emotions in particular, may be central to the PTSD and the PTSD/suicidal ideation comorbidity networks. The present study applied network analysis to identify 1) central symptoms in PTSD, and 2) bridging symptoms that may account for the comorbidity between PTSD and suicidal ideation. In both networks, the DSM-5 PTSD symptoms D2, D3, and D4 were disentangled, where the cognitions and emotions (negative thoughts about the self, self-blame, negative thoughts about the world, blaming others, anger, fear, shame, and guilt) within these symptoms were measured and analyzed as separate variables. Additionally, variables from the …

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Switching Between The L1 And L2: Teachers Corrective Feedback And Learner Uptake, Md Nesar Uddin Jan 2021

Switching Between The L1 And L2: Teachers Corrective Feedback And Learner Uptake, Md Nesar Uddin

Electronic Theses and Dissertations Archive

Over the years, an interest in switching between the L1 and L2 in L2 classroom instruction has grown in SLA research in parallel with the uptick in corrective feedback (CF) research. Separate studies on CF (e.g., Shirani, 2019; Bryfonski & Ma, 2020) and L1 use (e.g., Iyitoglu, 2016) have found that CF and language switching promote L2 learning, with L1 use facilitating the accomplishment of cognitively demanding tasks. However, research has not considered how switching between languages in the provision of CF impacts learning opportunities. This dissertation combined CF and language switching and explored the role of CF practices in …

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Exitosos, A Pesar De Todo: What Is The Nature Of Ethnic And Scholar Identity For High-Achieving High School Latinx Students Who Identify As A Boy In A Southern Context?, Alyssa Jasina Villarreal Jan 2021

Exitosos, A Pesar De Todo: What Is The Nature Of Ethnic And Scholar Identity For High-Achieving High School Latinx Students Who Identify As A Boy In A Southern Context?, Alyssa Jasina Villarreal

Electronic Theses and Dissertations Archive

The present study investigated the nature of the ethnic and scholarly identity development in high-achieving, high school students who identify as both Latinx and as a boy. Further the study explored any interactions between the ethnic and scholarly identities of participants. By conducting this study, it is the researchers hope that documented the student testimonios contributed to the preparation of teachers, school administrators, and families understandings on what leads to success. Furthermore, the study will contribute to the validity of the importance of identifying and acknowledging the individuality each student brings to the classroom and unique experiences that have contributed …

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Statistical Methods For Patterns And Interconnections Between Variables With Applications In Epigenetics Data, Jiajing Wang Jan 2021

Statistical Methods For Patterns And Interconnections Between Variables With Applications In Epigenetics Data, Jiajing Wang

Electronic Theses and Dissertations Archive

Epigenetics is one possible mechanism explaining the disease heritability withoutchanging DNA sequence. DNA methylation (DNAm), as an epigenetic factor with amemory of environmental exposure, may potentially explain the existing missingheritabability. Learning the patterns of DNAm transmission at different CpG sites andstudying the interconnection among the transmitted CpG sites is beneficial to diseaseprediction and prevention. In my dissertation, I will focus on two perspectives to study thetransmission of DNA methylation: clustering and network.The first project describes a nested Bayesian clustering method to identify DNAmethylation (DNAm) sites (CpG sites) such that DNAm is transmitted from onegeneration to the next, and to study …

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A Longitudinal Examination Of The Relation Of Profiles Of Children Based On Overt, Relational, And Cyber Aggression, To Assessments Of Peer Liking And Popularity, Robert Washington Jan 2021

A Longitudinal Examination Of The Relation Of Profiles Of Children Based On Overt, Relational, And Cyber Aggression, To Assessments Of Peer Liking And Popularity, Robert Washington

Electronic Theses and Dissertations Archive

The present research examined the association of empirically derived, person centered profiles based on overt, relational, and cyber aggression to peer liking and popularity over a two-year period. Children from six cohorts of grades 3 5 (IRB approved) participated in the study (boys = 127, girls = 165; primarily middle-class SES families). A latent profile analysis (LPA) was conducted using third grade levels of the three subtypes of aggression. Three distinct groups were identified: non-aggressive (low in all three forms), traditionally aggressive (high only in overt and relational aggression), cyber aggressive (only high in cyber aggression). Growth curve models indicated …

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Zora Neale Hurston's Thier Eyes Were Watching God And Other Works: The Catalyst For Understanding Imbalances Of Black Love As Seen In Pop Culture, Dale Michelle Williams Jan 2021

Zora Neale Hurston's Thier Eyes Were Watching God And Other Works: The Catalyst For Understanding Imbalances Of Black Love As Seen In Pop Culture, Dale Michelle Williams

Electronic Theses and Dissertations Archive

The state of African American romantic love and marriage has garnered increased scrutiny over the last 20 years, sparking great attention among scholarly studies, pop culture, and mainstream media to combat marriage decline. African American literature offers a complex view of marriage and romantic love via the works of Zora Neale Hurston as early as the 1930s that predates other studies. Hurstons Their Eyes Were Watching God and Hitting a Straight Lick with a Crooked Stick are the catalysts for understanding black romantic love, questions of marriage, and concerns about black male and female relationships then and now. A close …

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On Density Of Smooth Functions In Musielak Orlicz Sobolevspaces And Uniform Convexity Of Those Spaces, Mariusz Żyluk Jan 2021

On Density Of Smooth Functions In Musielak Orlicz Sobolevspaces And Uniform Convexity Of Those Spaces, Mariusz Żyluk

Electronic Theses and Dissertations Archive

\ind \.Zyluk, Mariusz Ph.D. The University of Memphis. May 2021. On density of smooth functions in Musielak Orlicz Sobolev spaces and uniform convexity. Major Professor: Anna Kami\'nnska, Ph.D.\ind We study density of smooth functions in Musialka Orlicz Sobolev $W^{k,\Phi}$ spaces as well as uniform convexity in those spaces.\ind We start with studying Musielak Orlicz spaces $L^\Phi$ and their basic properties. We improve some basic results by dropping the assumption of local integrability. Next, we characterize the density of compact supported smooth functions ($C_C^\infty$) in a Musielak Orlicz spaces $L^\Phi$ generated by a functions $\Phi$ that are not necessarily locally integrable.\ind …

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A Hardware-Software Co-Designed Wearable For Real-Time Physiological Data Collection And Signal Quality Assessment, Md Sabbir Bin Zaman Jan 2021

A Hardware-Software Co-Designed Wearable For Real-Time Physiological Data Collection And Signal Quality Assessment, Md Sabbir Bin Zaman

Electronic Theses and Dissertations Archive

In the future, Smart and Connected Communities (S&CC) will use distributed wireless sensors and embedded computing platforms to produce meaningful data that can help individuals, and communities. Here, we presented a scanner, a data reliability estimation algorithm and Electrocardiogram (ECG) beat classification algorithm which contributes to the S&CC framework .In part 1, we report the design, prototyping, and functional validation of a low-power, small, and portable signal acquisition device for these sensors. The scanner was fully tested, characterized, and validated in the lab, as well as through deployment to users homes. As a test case, we show results of the …

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The Behavior Of Rotation Criteria In Exploratory Factor Analysis With Ordinal Data: The Role Of Number Of Indicators And Number Of Factors, Rachel Lynn Ankney Jan 2021

The Behavior Of Rotation Criteria In Exploratory Factor Analysis With Ordinal Data: The Role Of Number Of Indicators And Number Of Factors, Rachel Lynn Ankney

Electronic Theses and Dissertations Archive

Many considerations influence the results of exploratory factor analysis (EFA) including rotation criteria and estimation method. Past research has given recommendations for matching estimation method to measurement of indicator variables, and some recommendations exist for the choice of rotation criteria across item complexity and factor intercorrelation. Less guidance exists, however, on rotation recommendations across number of factors and indicators included in the model. To fill this gap, the present study manipulated the number of factors and indicators in EFA models with ordinal data across multiple rotation criteria and across additional data considerations. Using Monte Carlo methods, data were generated (1,000 …

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Bayesian And Maximum Likelihood Estimation For Correlated Binary Data Based On The Double Binomial Distribution, John Appiah Kubi Jan 2021

Bayesian And Maximum Likelihood Estimation For Correlated Binary Data Based On The Double Binomial Distribution, John Appiah Kubi

Electronic Theses and Dissertations Archive

In the statistical analysis of binary data, usually the binomial distribution is themost commonly used probability model in many applications. The binomial is a very usefuldistribution in many practical applications due to its simplicity and having a parameter thathas an intuitive meaning. However, it has a unique feature that is the variance depending onthe mean, an assumption that does not reflect reality in many practical applications especiallyin cases where the data exhibits greater variability than predicted by the distribution. Thetwo-parameter double binomial model introduced by Efron (1986) may be considered as auseful alternative to the one-parameter binomial distributions, given that …

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Complexity, Accuracy And Fluency, Reformulation As A Corrective Feedback Strategy In Pair And Individual Writing And Revision: A Study In An Efl Context, Abdul Hakim Jan 2021

Complexity, Accuracy And Fluency, Reformulation As A Corrective Feedback Strategy In Pair And Individual Writing And Revision: A Study In An Efl Context, Abdul Hakim

Electronic Theses and Dissertations Archive

Some research (e.g., Dobao, 2012; Shehadeh, 2011; Wigglesworth & Storch, 2009; Storch, 2005) suggests that collaborative L2 writing results in higher quality L2 writing production than individual writing. Similarly, collaborative L2 writing has also been found to bring about more L2 learning opportunities for learners (e.g., Dobao & Blum, 2013; Dobao, 2012; Wigglesworth & Storch, 2012; Brooks & Swain, 2009). However, much is still unknown about how CW promotes higher quality L2 writing and other L2 learning opportunities. The purpose of the current study was to examine second language collaborative writing in an under-researched EFL context to determine (1) whether …

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Exploring Associations Between Adverse Childhood Experiences, Emotion Regulation, And Problem Behaviors Among Adolescents In Residential Treatment, Kiersten Alicia Hawes Jan 2021

Exploring Associations Between Adverse Childhood Experiences, Emotion Regulation, And Problem Behaviors Among Adolescents In Residential Treatment, Kiersten Alicia Hawes

Electronic Theses and Dissertations Archive

The high prevalence of conditions among adolescents such as anxiety, depression, substance use and suicide has become a global concern. Given the growing rates of internalizing and externalizing behavioral problems at the onset of adolescence, researchers have begun to find interest in identifying associations that account for dysfunctional patterns and problem behaviors. Findings suggest that these negative psychological and behavioral outcomes could be linked to exposure to adverse childhood experiences (ACEs) like abuse, neglect, violence, and household dysfunction. The present study investigated associations between ACEs, difficulties in emotion regulation, and problem behaviors among a sample of 43 adolescents age 11-17 …

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Reclaiming The Revolutionaries: African American Organizing During The Interwar Period In Memphis, Tennessee, Matthew Isaacs Jan 2021

Reclaiming The Revolutionaries: African American Organizing During The Interwar Period In Memphis, Tennessee, Matthew Isaacs

Electronic Theses and Dissertations Archive

The global black freedom struggle of the early twentieth century took many turns, while building momentum into the post-World War II era. Along the way, an interracial coterie of activists and disparate organizations rallied around a mass movement for black advancement. They enlarged avenues of resistance and developed strategies for cooperative alliances that laid the groundwork for future organizations and activists, often in areas that remain understudied. This dissertation examines one of those locations, Memphis, Tennessee, and its engagement with the global black freedom struggle during the interwar period. Due to a convergence of local, national, and international forces, the …

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The Empirical Relationship Between Cds Premiums, Bond Yields, And Stock Prices During The 2007-2008 Financial Crisis: Causality, Co-Movement And Price Discovery, Yi Lu Jan 2021

The Empirical Relationship Between Cds Premiums, Bond Yields, And Stock Prices During The 2007-2008 Financial Crisis: Causality, Co-Movement And Price Discovery, Yi Lu

Electronic Theses and Dissertations Archive

This dissertation provides a comprehensive study of the credit-default swaps (CDS). In the short-run, we review and synthesize literature across disciplines and offer a theoretical framework of the empirical relationship between CDS premiums, bond yields, and stock prices. Theoretically, the credit risk captured by CDS and bond spreads should be equal, since both CDS and bond spreads are the risk premiums associated with corporations risky instruments. However, data reveal a significant difference between the two spreads. Stock prices, as well, should impact CDS and bond spreads. In a panel time-series framework with daily data of 96 corporations from North America, …

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Three Essays In Economics: Superfund Sites Revisit - The Heterogeneous Effects Of Us And China Trade War - The Selected Firms Level Impact Of The U.S.-China Trade Conflicts, Duy Nguyen Jan 2021

Three Essays In Economics: Superfund Sites Revisit - The Heterogeneous Effects Of Us And China Trade War - The Selected Firms Level Impact Of The U.S.-China Trade Conflicts, Duy Nguyen

Electronic Theses and Dissertations Archive

In the first essay, hedonic regression on transaction data is the favored method to measure the impact of adverse environmental characteristics. However, this method only weakly identifies the direct causal relationship of unfavorable factors on house prices. The paper found a weak negative impact of 23% on the house price index in the early stage between treatment and control zip code using a robust two-way fixed effects estimation. The diagnostic of the two-way fixed effects estimators found no issues with negative weights, but the sites exhibit a wide range of heterogeneous treatment effects. In the second essay, we found empirically …

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Detection And Explanation Of Distributed Denial Of Service (Ddos) Attack Through Interpretable Machine Learning, Saikat Das Jan 2021

Detection And Explanation Of Distributed Denial Of Service (Ddos) Attack Through Interpretable Machine Learning, Saikat Das

Electronic Theses and Dissertations Archive

Distributed denial of service (DDoS) is a network-based attack where the aim of the attacker is to overwhelm the victim server. The attacker floods the server by sending enormous amount of network packets in a distributed manner beyond the servers capacity and thus causing the disruption of its normal service. In this dissertation, we focus to build intelligent detectors that can learn by themselves with less human interactions and detect DDoS attacks accurately. Machine learning (ML) has promising outcomes throughout the technologies including cybersecurity and provides us with intelligence when applied on Intrusion Detection Systems (IDSs). In addition, from the …

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Allah Made Me This Way: Negotiating Identities For Muslim Americans With Same-Sex Attraction, Emily El-Oqlah Jan 2021

Allah Made Me This Way: Negotiating Identities For Muslim Americans With Same-Sex Attraction, Emily El-Oqlah

Electronic Theses and Dissertations Archive

To date, little research has focused on the experiences of U.S. Muslims with same-sex attraction. The purpose of this study is to extend research on the experiences of Muslims in the United States of America who have same-sex or same-gender attraction. This study sought to answer the following research questions: (1) How do LGBQ+ Muslims negotiate their intersecting identities? (2) What are experiences with discrimination or acceptance in and out of the Muslim community? (3) How do LGBQ+ Muslims approach the topic of coming out to their communities? and (4) What do mental health professionals need to know when working …

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Explanation Techniques Using Markov Logic Networks, Khan Mohammad Al Farabi Jan 2021

Explanation Techniques Using Markov Logic Networks, Khan Mohammad Al Farabi

Electronic Theses and Dissertations Archive

Explaining the results of Artificial Intelligence (AI) or Machine Learning (ML) algorithms is crucial given the rapid growth and potential applicability of these methods in critical domains including healthcare, defense, autonomous driving, etc. While AI/ML approaches yield highly accurate results in many challenging tasks such as natural language understanding, visual recognition, game playing, etc., the underlying principles behind such results are not easily understood. Thus, the trust in AI/ML methods for critical application domains is significantly lacking. While there has been progress in explaining classifiers, there are two significant drawbacks. First, current explanation approaches assume independence in the data instances …

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Waveform And Geodynamic Modeling Of Seismicity Associated With The Charlevoix Seismic Zone, Oluwaseun Idowu Fadugba Jan 2021

Waveform And Geodynamic Modeling Of Seismicity Associated With The Charlevoix Seismic Zone, Oluwaseun Idowu Fadugba

Electronic Theses and Dissertations Archive

The Charlevoix seismic zone (CSZ) is the most seismically active region in eastern Canada. It is located within the Late Proterozoic-Early Cambrian St. Lawrence rift zone in southeastern Quebec. The location was also the site of a Devonian impact crater. The CSZ poses a high seismic risks due to its seismicity compared to the other seismic zones in the area and its proximity to densely populated cities (e.g., Quebec City, Ottawa, and Montreal). It is also responsible for much of the seismic hazard in New England. Previous studies in the CSZ observed a maximum compressive stress orientation of N86, which …

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A Ground-Motion Prediction Model For Small-To-Moderate Induced Earthquakes For Central And Eastern United States And Ground Motion Model Ranking, Zoya Farajpour Jan 2021

A Ground-Motion Prediction Model For Small-To-Moderate Induced Earthquakes For Central And Eastern United States And Ground Motion Model Ranking, Zoya Farajpour

Electronic Theses and Dissertations Archive

This dissertation concerns developing a new ground motion model (GMM) for small to moderate potentially induced seismic events in Central and Eastern United States (CEUS) and ranking worldwide and local GMMs for Iran. The body of research work is carried out in two related studies.The first study presents a new GMM. The proposed model is developed considering induced and potentially induced seismic events in CEUS. For this study, a comprehensive flatfile of potentially induced ground motions for moment magnitudes (Mw) between 3 and 6 and distances of less than 200 km is used. The Pezeshk et al. (2018) model, which …

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School Counselors And Academic Outcomes Among Secondary School Students In One Southeastern District, Martha Burke Jan 2021

School Counselors And Academic Outcomes Among Secondary School Students In One Southeastern District, Martha Burke

Electronic Theses and Dissertations Archive

The purpose of this study is to explore the relationship between school counselor ratios, and Tennessee Comprehensive Assessment Program [TCAP] English Language Arts and Mathematics scores. This study will also consider school level characteristics and student level characteristics in one large, public, urban school district in the southeastern United States. This study will merge two archival data sets from the 2018-2019 school year. Both data sets were downloaded from the Tennessee Department of Educations website and are publicly available. The first data set contains demographic information listed by school. The second data set contains TCAP testing score reports by school. …

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The Comparative Effects Of Modified Augmentative And Alternative Communication Modalities On Requesting For A Child With Autism And Visual Impairments, Mallorie Hutton Caradine Jan 2021

The Comparative Effects Of Modified Augmentative And Alternative Communication Modalities On Requesting For A Child With Autism And Visual Impairments, Mallorie Hutton Caradine

Electronic Theses and Dissertations Archive

The present study used a multiple probe across behaviors design, with an embedded alternating treatments design to compare the effects of two modified communication systems, the Picture Exchange Communication System (PECS) and a speech generating device, on requesting for a child with multiple disabilities, including autism and visual impairments. Both modalities were taught across the first three phases of PECS instruction (simple request, distance and persistence, and discrimination). During baseline the participant demonstrated little to no requesting across all three phases for either modality. During intervention requesting increased to proficient levels across all three phases for both modalities. Modified PECS, …

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Exploratory Look Into The Impact Of Race On Response Dynamics While Categorizing Stereotypical Black Names And Stereotypical White Names Via Mouse Movements, Taylor Clark Jan 2021

Exploratory Look Into The Impact Of Race On Response Dynamics While Categorizing Stereotypical Black Names And Stereotypical White Names Via Mouse Movements, Taylor Clark

Electronic Theses and Dissertations Archive

Racial bias (especially in the context of Black people) in society is as prevalent as ever. Because of this, scientists have developed various ways to measure racial bias against Black people. I propose that mouse tracking is a tool that can be used to predict racially biased behavior accurately. The overall purpose of this exploratory study was to use mouse tracking to investigate whether race impacts participants' mouse movements when categorizing stereotypically sounding Black and White names. As well as to see if participants consistently categorize Black and White names. This experiment showed a significant difference in the number of …

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Do Not Feed The Fetishizers: Boys Love Fans Resistance And Challenge Of Perceieved Reputation, Hailey Rose Coleman Jan 2021

Do Not Feed The Fetishizers: Boys Love Fans Resistance And Challenge Of Perceieved Reputation, Hailey Rose Coleman

Electronic Theses and Dissertations Archive

Existing research on Boys Love (BL) fans has focused primarily on heterosexual womens consumption of the media. Queer audience members have rarely been included in BL studies. Drawing on autoethnographic materials and 36 in-depth interviews, this project documented the ways that individuals who self-identify as BL fans created, resisted, and challenged the perceived stigma that all BL fans are fetishizers of gay men. Respondents relied on Biographical Work to construct their identities and frame their experiences with BL media in relation to fetishizer exemplars. Some participants engaged in Identity Politics where they made claims about the wrong ways and right …

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Graphic Agency: Teaching Graphic Medicine In The Liberal Arts Classroom, Esther Bendit Saltzman Jan 2021

Graphic Agency: Teaching Graphic Medicine In The Liberal Arts Classroom, Esther Bendit Saltzman

Electronic Theses and Dissertations Archive

Comics and graphic novels, as well as comics studies courses, are being increasingly recognized as important multimodal texts in higher education. Medically themed comics and graphic novels, or graphic medicine texts, however, have not been used as frequently as the basis for course offerings, and there is a need for them to be used and for their significance to be studied.This dissertation advocates for the inclusion of graphic medicine in college curricula because of its ability to demonstrate and facilitate agency. As my readings of graphic medicine texts and my pedagogical explorations indicate, medically themed graphic texts express themes of …

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Select Life/Delete/New Page, Jeremy D. Scherer Jan 2021

Select Life/Delete/New Page, Jeremy D. Scherer

Electronic Theses and Dissertations Archive

The novella Select Life/Delete/New Page" by Jeremy Scherer follows the story of Nopok, a young man who works in a computer lab while pursuing a political science degree. Lacking any direction in his academic or professional lives, Nopok suffers at home, where his parents use him and his brother Sammy as proxies to act out their obvious dysfunction. Nopok's only escape is his online life, where he finds meaning as a user on the gaming website Gamefaqs, where he provides people with gaming advice and fits into an odd, but endearing community of artists and gamers. When Nopok's mother threatens …

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Entrepreneurial Developments In The Life And Works Of Johann Sperger (17501812), Joel Scott Schnackel Jan 2021

Entrepreneurial Developments In The Life And Works Of Johann Sperger (17501812), Joel Scott Schnackel

Electronic Theses and Dissertations Archive

Adolf Meiers Konzertante Musik fr Kontraba in der Wiener Klassik shows how the contrabass player and composer Johann Matthias Sperger (17501812) participated in both the public and private arenas of high society, toured as a soloist, and played in the leading Kapelle orchestras. His mastery of his instrument, which earned him the reputation of being one of the greatest soloists on the Viennese contrabass, has to this day overshadowed his reputation as a composer. This dissertation builds upon Meiers work, concentrating on Sperger as an entrepreneurial composer-performer who over time developed the skills of what today we would call strategic …

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The Effect Of Pre- And Postnatal Diet Exposure On Gut Morphology, Function And Inflammation, Suman Sharma Jan 2021

The Effect Of Pre- And Postnatal Diet Exposure On Gut Morphology, Function And Inflammation, Suman Sharma

Electronic Theses and Dissertations Archive

Consumption of high fat diet and obesity have been shown to increase risk of intestinal inflammation. Interestingly, early life exposure to a high fat diet (HFD), during gestation and lactation, also increases the risk of these inflammatory gut conditions in the offspring even in adulthood. Therefore, we hypothesized that using a rationally designed diet containing high amounts of fermentable fiber and omega-3 fatty acids, components that are known to improve gut inflammation, and providing this diet at weaning will improve inflammatory conditions later in life. Healthy (8 male and 8 female) C57BL/6 mice were used. 6 pairs were given HF …

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