Digital Commons Network^™

In Vivo Magnetic Resonance Spectroscopy Of Hyperpolarized [1-13C]Pyruvate And Proton Density Fat Fraction In A Guinea Pig Model Of Non-Alcoholic Fatty Liver Disease Development After Life-Long Western Diet Consumption, Lauren M. Smith, Conrad B. Pitts, Lanette J. Friesen-Waldner, Neetin H. Prabhu, Katherine E. Mathers, Kevin J. Sinclair, Trevor P. Wade, Timothy R.H. Regnault, Charles A. Mckenzie

Obstetrics & Gynaecology Publications

Background: Alterations in glycolysis are central to the increasing incidence of non-alcoholic fatty liver disease (NAFLD), highlighting a need for in vivo, non-invasive technologies to understand the development of hepatic metabolic aberrations. Purpose: To use hyperpolarized magnetic resonance spectroscopy (MRS) and proton density fat fraction (PDFF) magnetic resonance imaging (MRI) techniques to investigate the effects of a chronic, life-long exposure to the Western diet (WD) in an animal model resulting in NAFLD; to investigate the hypothesis that exposure to the WD will result in NAFLD in association with altered pyruvate metabolism. Study Type: Prospective. Animal Model: Twenty-eight male guinea pigs …

In Vivo Magnetic Resonance Spectroscopy Of Hyperpolarized [1-, Lauren M Smith, Conrad B Pitts, Lanette J Friesen-Waldner, Neetin H Prabhu, Katherine E Mathers, Kevin J Sinclair, Trevor P Wade, Timothy Regnault, Charles A Mckenzie

Paediatrics Publications

BACKGROUND: Alterations in glycolysis are central to the increasing incidence of non-alcoholic fatty liver disease (NAFLD), highlighting a need for in vivo, non-invasive technologies to understand the development of hepatic metabolic aberrations.

PURPOSE: To use hyperpolarized magnetic resonance spectroscopy (MRS) and proton density fat fraction (PDFF) magnetic resonance imaging (MRI) techniques to investigate the effects of a chronic, life-long exposure to the Western diet (WD) in an animal model resulting in NAFLD; to investigate the hypothesis that exposure to the WD will result in NAFLD in association with altered pyruvate metabolism.

STUDY TYPE: Prospective.

ANIMAL MODEL: Twenty-eight male guinea pigs …

Full Issue

Swiss American Historical Society Review

No abstract provided.

Peaks Island Star : November 2021, Vol. 41, Issue 11, Service Agencies Of The Island

Peaks Island Star, 2021

The Peaks Island Star is the newsletter of the island's service agencies and other community news.

Wrack Lines Volume 21, Number 2, Fall/Winter 2021-22, Nancy C. Balcom, Judy Benson, Syma A. Ebbin, Kira Goldenberg, Judy Preston, Howard "Mickey" Weiss

Wrack Lines

"Discovery, Rediscovery and Rebirth: new eyes, new understanding of familiar places" is the theme for the Fall-Winter 2021-22 issue. The main article package consists of five stories about the lands and waters that will comprise the Connecticut National Estuarine Research Reserve (CT NERR). These are: overview and introduction; Great Island; lower Thames River; Bluff Point State Park; and Haley Farm State Park. Other articles include one on research into the cause of invasive Cladophora seaweed dominating Little Narragansett Bay; and another on the transformation of the Yale Peabody Museum of Natural History.

Relating Multivariate Shapes To Genescapes Using Phenotype-Biological Process Associations For Craniofacial Shape, Jose D. Aponte, David C. Katz, Daniela M. Roth, Marta Vidal-García, Wei Liu, Fernando Andrade, Charles C. Roseman, Steven A. Murray, James Cheverud, Daniel Graf, Ralph S. Marcucio, Benedikt Hallgrímsson

Biology: Faculty Publications and Other Works

Realistic mappings of genes to morphology are inherently multivariate on both sides of the equation. The importance of coordinated gene effects on morphological phenotypes is clear from the intertwining of gene actions in signaling pathways, gene regulatory networks, and developmental processes underlying the development of shape and size. Yet, current approaches tend to focus on identifying and localizing the effects of individual genes and rarely leverage the information content of high-dimensional phenotypes. Here, we explicitly model the joint effects of biologically coherent collections of genes on a multivariate trait – craniofacial shape – in a sample of n = 1145 …

November 2021 Cvm Library Newsletter, Mississippi State University

CVM Library Newsletters

Newsletter of the College of Veterinary Medicine Library at Mississippi State University.

38th Annual Reception Bibliography, 2020-2021, Leonard H. Axe Library

Bibliographies

Since 1984, Leonard H. Axe Library at Pittsburg State University has honored book authors and other creators for their outstanding scholarship and contributions to their fields.

Nebline, Nov./Dec.2021

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

Holiday Food Tips

Recipes of the Month

Traditions Rituals and Routines During a COVID-19 Holiday Season

Wise Use of Private Water and Wastewater Systems Can Make the Holidays More Peaceful

Dormant Lawn Seeding

Garden Guide: Things to Do This Month

4-H Thanks 2021 Sponsors

Farmland Trends and Lease Considerations for 2022 Workshop

Upcoming Early Childhood Trainings

Ag Society Annual Election & Meeting

Heart of 4-H Volunteer Award, Jamie Wood

Heart of 4-H Volunteer Award, Julia Plugge

Slime, Jelly Worms & Goo: Food Science 4-H Workshop, Dec. 4

Finger Knit 4-H Workshop, Dec. 11

2021 4-H Horse Awards Night

4-H Announcements …

Hadron, Eunice Kim '22, Lily Song '22

Hadron Magazine

• Pg 4 : Anxiety and Evolution
• Pg 5 : Prescription Fires
• Pg 7 : The New Uber?
• Pg 8 : Changing Society
• Pg 10 : The Rare and Elusive Spirit Bear
• Pg 12 : How Lasers Could Solve the World Energy Crisis
• Pg 14 : The Physics of Water Wakes
• Pg 17 : Schwarzschild Cosmology and Black Hole-ception!
• Pg 19 : The Future of Space Tourism
• Pg 20 : Not Just Bitcoin
• Pg 21 : The Evolving Medical Power of Psychedelics
• Pg 24 : Usage of Hydrogels in Wound Healing
• Pg 26 : New COVID-19 Variant Spreading Across South America …

The Sulfur Microbial Diet Is Associated With Increased Risk Of Early-Onset Colorectal Cancer Precursors, Long H. Nguyen, Yin Cao, Jinhee Hur, Raaj S. Mehta, Daniel R. Sikavi, Yiqing Wang, Wenjie Ma, Kana Wu, Mingyang Song, Edward L. Giovannucci, Eric B. Rimm, Walter C. Willett, Wendy S. Garrett, Jacques Izard, Curtis Huttenhower, Andrew T. Chan

Food for Health: Publications

Background and aims: Diet may contribute to the increasing incidence of colorectal cancer (CRC) before age 50 (early-onset CRC). Microbial metabolism of dietary sulfur produces hydrogen sulfide (H₂S), a gastrointestinal carcinogen that cannot be easily measured at scale. As a result, evidence supporting its role in early neoplasia is lacking.

Methods: We evaluated long-term adherence to the sulfur microbial diet, a dietary index defined a priori based on increased abundance of 43 bacterial species involved with sulfur metabolism, with risk of CRC precursors among 59,013 individuals who underwent lower endoscopy in the Nurses’ Health Study II …

Methacrylated Collagen And Hnt Composite Hydrogels For Application In Bone Tissue Regeneration, Yue Li

Doctoral Dissertations

Fractures and segmental bone defects are the primary cause of patient morbidity and brings a substantial economic burden to the healthcare system. Bone grafts used for bone injuries, tumors, and other pathologies related to poor fracture healing in the United States cost considerable money each year. The total cost of treating bone defects is about 5 billion US dollars. Autologous bone transplantation is the ideal method for the treatment of bone defects. However, their clinical results are variable and increase postoperative morbidity (especially at the donor site) and surgical costs. To circumvent these limitations, tissue engineering and cell-based therapies have …

A Network Biology Approach To Understanding The Tissue-Specific Roles Of Non-Coding Rnas In Arthritis, Shabana A. Ali, Chiara Pastrello, Navdeep Kaur, Mandy J. Peffers, Michelle J. Ormseth, Igor Jurisica

Orthopedics Articles

Discovery of non-coding RNAs continues to provide new insights into some of the key molecular drivers of musculoskeletal diseases. Among these, microRNAs have received widespread attention for their roles in osteoarthritis and rheumatoid arthritis. With evidence to suggest that long non-coding RNAs and circular RNAs function as competing endogenous RNAs to sponge microRNAs, the net effect on gene expression in specific disease contexts can be elusive. Studies to date have focused on elucidating individual long non-coding-microRNA-gene target axes and circular RNA-microRNA-gene target axes, with a paucity of data integrating experimentally validated effects of non-coding RNAs. To address this gap, we …

Faculty Senate Minutes, November 1, 2021, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• Approval of Minutes – October 4, 2021
• University Business
• Educational Policies Committee – October 6, 2021
• PRPC Update
• Athletic Council Annual Report
• Honors Program Annual Report
• Old Business

Tribe’S Trajectory & Lgbtq Rights, Joshua Matz

University of Chicago Law Review

I’m not sure I’ll ever live it down. I actually said—out loud, to his face, a full ten minutes into our very first conversation—“Holy smokes, you’re Larry Tribe!” I was in Cambridge that day as a newly admitted student. Somehow, inexplicably (it’s not that big of a campus), I got lost. Very lost. Fortunately, a passerby professor took mercy and steered me to his office. In a bid to regain my composure, and to seem like a plausible future law student, I jumped straight to explaining why I was there: I wanted to be a civil rights lawyer. To prove …

Characteristics Of Organ Donors Who Died From Suicide By Hanging In Australia And New Zealand: A Retrospective Study, Mohamed Fayed, Raju Pusapati, Neil Widdicombe, Matthew Sypek, Rowaa Ibrahim, Nicholas S Yeldo, Donald Penning

Anesthesiology Articles

Background and objective: The annual incidence of suicide by hanging in Australia and New Zealand has increased in the past decade, and a significant number of these individuals are becoming organ donors. The rates of organ donation following deaths from hanging is unknown and the characteristics of this cohort of donors have not been described in the literature. In light of this, we aimed to examine the trends in organ donation from individuals who had died from hanging, based on the solid organ donor data from the Australia and New Zealand Organ Donation (ANZOD) Registry.

Methods: We conducted a retrospective …

Experimental Challenge Of A North American Bat Species, Big Brown Bat (Eptesicus Fuscus), With Sars-Cov-2, Jeffrey S. Hall, Susan Knowles, Sean W. Nashold, Hon S. Ip, Ariel E. Leon, Tonie Rocke, Saskia Keller, Mariano Carossino, Udeni Balasuriya, Erik Hofmeister

KIP Articles

No abstract provided.

Intraspecific Variation Mediates Density Dependence In A Genetically Diverse Plant Species, Andrii Zaiats, Matthew J. Germino, Marcelo D. Serpe, Bryce Richardson, T. Trevor Caughlin

Biology Faculty Publications and Presentations

Interactions between neighboring plants are critical for biodiversity maintenance in plant populations and communities. Intraspecific trait variation and genome duplication are common in plant species and can drive eco-evolutionary dynamics through genotype-mediated plant-plant interactions. However, few studies have examined how species-wide intraspecific variation may alter interactions between neighboring plants. We investigate how subspecies and ploidy variation in a genetically diverse species, big sagebrush (Artemisia tridentata), can alter the demographic outcomes of plant interactions. Using a replicated, long-term common garden experiment that represents range-wide diversity of A. tridentata, we ask how intraspecific variation, environment, and stand age mediate …

A Draft Genome Provides Hypotheses On Drought Tolerance In A Keystone Plant Species In Western North America Threatened By Climate Change, Anthony E. Melton, James Beck, Stephanie J. Galla, Marcelo Serpe, Stephen Novak, Sven Buerki

Biology Faculty Publications and Presentations

Climate change presents distinct ecological and physiological challenges to plants as extreme climate events become more common. Understanding how species have adapted to drought, especially ecologically important nonmodel organisms, will be crucial to elucidate potential biological pathways for drought adaptation and inform conservation strategies. To aid in genome-to-phenome research, a draft genome was assembled for a diploid individual of Artemisia tridentata subsp. tridentata, a threatened keystone shrub in western North America. While this taxon has few genetic resources available and genetic/genomics work has proven difficult due to genetic heterozygosity in the past, a draft genome was successfully assembled. Aquaporin …

Shame, Hope And The Church: A Journey With Mary, Glenn Morrison

Pastoral Liturgy

No abstract provided.

3rd Sunday Of Advent - 12 December 2021, Gerard Moore

Pastoral Liturgy

No abstract provided.

The Role Of Zingiberales Shared Evolutionary History And Leaf Traits In Structuring Rolled-Leaf Beetle Assemblages In A Tropical Forest, José Miguel Chaves Fallas

Dissertations

Understanding how local assemblages of plants and animals are structured is a central challenge for evolutionary ecology. Tropical assemblages are high in species numbers and in variety of ecological interactions, providing unique multispecies biological systems to test ecological and evolutionary hypotheses about community assembly. The objective of this dissertation was to understand the role of Zingiberales shared evolutionary history and plant traits for structuring the rolled-leaf beetle (Cephaloleia and Chelobasis, Chrysomelidae) assemblage in a lowland wet forest (La Selva Biological Station) of Costa Rica.

In chapter I studied the evolution of physical, nutritional, and chemical leaf traits, how …

Severe Emotional And Behavioral Problems: Barriers For Texas Youth Accessing Mental Health Court Programs, Justin Joseph

Contemporary Issues in Juvenile Justice

Conduct disorder is a constellation of continuous emotional and behavioral problems observed in children and adolescents, which may involve violent and non-violent antisocial behaviors. The symptomology of this psychological disorder includes: disregarding rules without clear reason, cruel or aggressive behavior toward people or animals (e.g., bullying, fighting, using dangerous weapons, forcing sexual activity, and stealing), skipping school, excessive substance use, pathological lying, manipulation, running away, and vandalism (American Psychiatric Association (APA), 2013). Texas Juvenile Mental Health Courts are designed to reduce the number of detained youth, divert at-risk children, maintain community safety, and utilize multidisciplinary approaches to treat conduct disordered …

Hospitality To The Wild, Laura Hartman

Intersections

No abstract provided.

Tremblings, November 2021, Western Aspen Alliance

Tremblings

Lindroth + Aspen: A Legacy of Good Chemistry

Ken Keefover-Ring

The license plates on Professor Rick Lindroth’s vehicle read “Q ASPEN,” referring to quaking aspen. This gives you a hint of the extent of his obsession; one he will surely carry into his upcoming retirement. Rick has co-authored almost 220 peer-reviewed articles and 15 book chapters over his academic career and more than 70% of them involve aspen (Populus tremuloides) in some way. In fact, many issues of Tremblings have listed one or more of his papers. This research has largely been focused on aspen chemical ecology and …

Media Consolidation & Political Polarization: Reviewing The National Television Ownership Rule, Mary R. Hornak

Fordham Law Review

Local television plays an important role in the democratic society. The medium is viewed as being trustworthy, and it is accessible and uniquely situated to report on matters of local interest. Among other roles, the Federal Communications Commission (FCC) regulates firms’ ownership interests in the media through regulations that permit a certain degree of consolidation at both the local and national levels. Since 1996, Congress has mandated that the FCC regularly review broadcast media ownership regulations. Originally, this requirement mandated biennial review. In 2004, however, Congress revised the mandate, requiring review on a quadrennial basis and excluding from such review …

Treprostinil Alleviates Hepatic Mitochondrial Injury During Rat Renal Ischemia-Reperfusion Injury, Joyce Hou, Tolbert, Mark Birkenbach, Nisanne S. Ghonem

Pharmacy Practice and Clinical Research Faculty Publications

Background: Renal ischemia-reperfusion injury (IRI) causes acute kidney injury as well as liver injury. Renal IRI depletes hepatic antioxidants, promotes hepatic inflammation and dysfunction through Tlr9 upregulation. There is no treatment available for liver injury during renal IRI. This study examines the hepatoprotective role of treprostinil, a prostacyclin analog, during renal IRI. Methods: Male Sprague-Dawley rats were divided into four groups: control, sham, IRI-placebo, or IRI-treprostinil and subjected to bilateral ischemia (45 min) followed by reperfusion (1–72 h). Placebo or treprostinil (100 ng/kg/min) was administered subcutaneously via an osmotic minipump. Results: Treprostinil significantly reduced peak serum creatinine, BUN, ALT and …

Ancient Dna Of The Pygmy Marmoset Type Specimen Cebuella Pygmaea (Spix, 1823) Resolves A Taxonomic Conundrum, J. P. Boubli, M. C. Janiak, L. M. Porter, Stella De La Torre, L. Cortés-Ortiz, M. N. F. Da Silva, A. B. Rylands, Stephen Nash, F. Bertuol, H. Byrne, F. E. Silva, F. Rohe, D. De Vries, R. M. D. Beck, I. Ruiz-Gartzia, L. F. K. Kuderna, T. Marques-Bonet, Tomas Hrbek, I. P. Farias, A. H. Van Heteren, C. Roos

Biology Faculty Research

The pygmy marmoset, the smallest of the anthropoid primates, has a broad distribution in Western Amazonia. Recent studies using molecular and morphological data have identified two distinct species separated by the Napo and Solimões-Amazonas rivers. However, reconciling this new biological evidence with current taxonomy, i.e., two subspecies, Cebuella pygmaea pygmaea (Spix, 1823) and Cebuella pygmaea niveiventris (Lönnberg, 1940), was problematic given the uncertainty as to whether Spix’s pygmy marmoset (Cebuella pygmaea pygmaea) was collected north or south of the Napo and Solimões-Amazonas rivers, making it unclear to which of the two newly revealed species the name pygmaea would …

Subspecific Designation Of The U.S.A. Interior Highlands Population Of Argynnis (Speyeria) Diana (Cramer, 1777) (Nymphalidae: Heliconiinae: Argynnini: Argynnina), Harry Pavulaan

The Taxonomic Report of the International Lepidoptera Survey

Subspecific designation is designated for the North American Interior Highlands population of Argynnis diana, based on four factors: mtDNA haplotype differences from nominotypical A. diana of the Appalachian Mountains; wing shape difference in the males between both regions; wing size of the adults; and tendency for females of the Interior Highlands to show tan coloration in the submarginal row of rectangular spots of the subapical region of the dorsal forewings.

Forage News [2021-11], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

No abstract provided.