Exercise To Delay The Progression Of Parkinson’S Disease, Kishorree Sangarapillai

Theses and Dissertations (Comprehensive)

The overall purpose of the current thesis was to evaluate the effect of exercise on the progression of Parkinson’s disease (PD). While many studies exist that investigate the effect of exercise on PD, they focus on immediate improvements and rarely consider washout periods, or any prolonged effects of exercise interventions. Thus, while short-term benefits are achievable, the more valuable influences of exercise on disease progression are often overlooked. Interestingly, according to animal models, high intensity exercise and low intensity strategies such as sensory training have been argued to have the potential to delay disease progression. In humans, the most popular …

Extracting Metallurgy Contaminants And Hydrocarbons Removing From Water And Industrial Wastewater Using Enhanced Emulsion Liquid Membrane With Nanoparticles And Ionic Liquid, Qusay Al-Obaidi

Doctoral Dissertations

It is an uphill battle to extract pollutants such as heavy metals, hydrocarbons, and radioactive metals from water and industrial wastewater. Emulsion liquid membrane (ELM) is an emerging technology that combines extraction/recover and stripping in one stage to extract/recover heavy metals and/or hydrocarbons from water and wastewater. ELM devised a way to clean up heavy metals and/or hydrocarbons from the water and wastewater where its primary chemicals can be recycled and reused.

In this work, the Emulsion Liquid Membrane (ELM) has been enhanced by adding nanoparticles and ionic liquid to significantly improve the recovery of the water-based contaminants of heavy …

Secure Data Sharing In Cloud And Iot By Leveraging Attribute-Based Encryption And Blockchain, Md Azharul Islam

Doctoral Dissertations

“Data sharing is very important to enable different types of cloud and IoT-based services. For example, organizations migrate their data to the cloud and share it with employees and customers in order to enjoy better fault-tolerance, high-availability, and scalability offered by the cloud. Wearable devices such as smart watch share user’s activity, location, and health data (e.g., heart rate, ECG) with the service provider for smart analytic. However, data can be sensitive, and the cloud and IoT service providers cannot be fully trusted with maintaining the security, privacy, and confidentiality of the data. Hence, new schemes and protocols are required …

Optimism At Work: Developing And Validating Scales To Measure Workplace Optimism, Sara Frost

Antioch University Dissertations & Theses

A growing body of research has shown the benefits of optimism on health, socioeconomic status, and at work. This two-phase mixed-method study revised and validated an instrument to measure an employee’s personal experience with optimism in their workplace. This study also developed two additional scales to measure the degree to which individuals engage in optimistic leadership skills, and an organization’s readiness to cultivate optimism. In Phase 1, 697 responses from an online survey were analyzed using exploratory and confirmatory factor analysis. Regression analysis indicated that an employee’s personal experience of factors associated with optimism at work influenced their perception of …

Applying The Present To The Past: The Experiences Of Five Civil Rights Rabbis In Context Of Contemporary Leadership Theory, Bradley G. Levenberg

Antioch University Dissertations & Theses

This dissertation examines the experiences of five civil rights-era rabbis (William Silverman, Randall Falk, Alfred Goodman, Irving Bloom, and Burton Padoll) to highlight their contributions, leadership approaches, struggles, and achievements with a particular emphasis on social justice. As each of the rabbis drew from their understanding of the richness of the Jewish textual canon, the study includes a survey of Biblical, Talmudic, and contemporary Jewish sources that laid the groundwork for their rabbinic activism and which compel rabbis today. The study dramatically highlights those texts as providing applicable strategies with regard to leading a congregation with a “prophetic” voice, knowing …

Human Centeredness: The Foundation For Leadership-As-Practice In Complex Local/Regional Food Networks, Maryann Martinez

Antioch University Dissertations & Theses

Our local and regional food systems are predominately modeled on a failed capitalist market-based economy. In the absence of corporate accountability, and/or support on the federal policy level, local and regional leadership and self-organized networks are critical to the scaling across and evolution of a moral and equitable food system. Networked food systems leaders are developing the capacity to solve wicked problems, and spark change. Understanding the values and practices of local food systems leadership that initiate, influence, and support activities is essential to understanding how to foster conditions for local and regional food network growth. My dissertation research is …

An Assessment Of Contamination Fingerprinting Techniques For Determining The Impact Of Domestic Wastewater Treatment Systems On Private Well Supplies, Chris Fennell, Bruce Misstear, David O'Connell, Donata Dubber, Patrice Behan, Martin Danaher, Mary Moloney, Laurence Gill

Articles

Private wells in Ireland and elsewhere have been shown to be prone to microbial contamination with the main suspected sources being practices associated with agriculture and domestic wastewater treatment systems (DWWTS). While the microbial quality of private well water is commonly assessed using faecal indicator bacteria, such as Escherichia coli, such organisms are not usually source-specific, and hence cannot definitively conclude the exact origin of the contamination. This research assessed a range of different chemical contamination fingerprinting techniques (ionic ratios, artificial sweeteners, caffeine, fluorescent whitening compounds, faecal sterol profiles and pharmaceuticals) as to their use to apportion contamination of private …

Parasite And The Ideological Barriers To Emancipatory Politics, Soravis Jayanama

Journal of Social Sciences

In this essay, my contention is two-fold. One, Bong Joon-ho’s f ilm Parasite (2019) is not simply about class inequality but more importantly addresses the question “what is (not) to be done?”.To appreciate this point, we have to investigate it alongside Bong’s previous f ilms, especially Snowpiercer (2013) and Okja (2017). Although these three f ilms possess vastly different storylines,they all wrestle with this burning political question from different angles: seizure of state power and revolution (Snowpiercer), “folk politics” (Okja), and neoliberal privatization of social problems (Parasite). They all implicitly demand for better or more concrete visions of systemic transformation. …

Psychometric Development Of The Autism Trait Survey, Gwendolyn S. Barnhart

Antioch University Dissertations & Theses

There are limited tools for professionals who work with individuals with autism to ascertain individuals’ strengths and challenges within the various facets of symptomology after diagnosis. Professionals can currently use personal interviews and psychological reports to determine individuals’ strengths and challenges to determine the types of services that would benefit them following initial diagnosis. The limitations of this practice are that the levels of understanding, accuracy, and use of these measures vary in the field. Furthermore, the norms of diagnostic measures are the entire population rather than solely individuals on the autistic spectrum/autistics (IOS/A). A new measure is necessary: one …

In Silico And In Vitro Screening For Potential Anticancer Candidates Targeting Gpr120, Ajay Pal, James Curtin, Gemma K. Kinsella

Articles

The G-protein coupled receptor - GPR120 has recently been implicated as a novel target for colorectal cancer (CRC) and other cancer managements. In this study, a homology model of GPR120S (short isoform) was generated to identify potential anti-cancer compounds targeting the GPR120 receptor using a combined in silico docking-based virtual screening (DBVS), structure-activity relationships (SAR) and in vitro screening approach. SPECS database of synthetic chemical compounds (~350,000) was screened using the developed GPR120S model to identify molecules binding to the orthosteric binding pocket followed by an AutoDock SMINA rigid-flexible docking protocol. The best 13 hit molecules were then tested in …

Seaweed Polysaccharide In Food Contact Materials (Active Packaging, Intelligent Packaging, Edible Films, And Coatings), Kalpani Perera, Shubham Sharma, Dileswar Pradhan, Amit Jaiswal, Swarna Jaiswal

Articles

Food contact materials (FCMs) are materials that come in contact with food products such as food packaging which play a significant role in food quality and safety. Plastic, which is a major food packaging material, harms the ecosystem, wildlife, and the environment. As a result, numerous researches have been in progress on alternative polymers, which have similar properties as plastic but are also environmentally friendly (biodegradable). In recent years, the utilization of seaweed polysaccharides has piqued interest due to their biodegradability, non-toxicity, antioxidant capabilities, and excellent film formation ability. However, it has a number of drawbacks such as low tensile …

Fruits And Vegetables In The Management Of Underlying Conditions For Covid-19 High-Risk Groups, Nora Moreb, Ahmed Albandary, Swarna Jaiswal, Amit Jaiswal

Articles

: SARS-CoV-2 or COVID-19 is a novel coronavirus, which is the cause of the current pandemic with 107,411,561 infections and 2,351,195 death worldwide so far. There are multiple symptoms that are linked with the infection of COVID-19 such as coughing, shortness of breath, congestion together with fatigue, fever, loss of taste or smell, headaches, diarrhea, vomiting, and loss of appetite. The lack of or early stage of development of a cure for COVID-19 illness, there is need for insuring the best possible position of health to be able to fight the virus naturally through a robust immune system to limit …

Salmonella, Food Safety And Food Handling Practices, Olugbenga Ehuwa, Amit Jaiswal, Swarna Jaiswal

Articles

: Salmonellosis is the second most reported gastrointestinal disorder in the EU resulting from the consumption of Salmonella-contaminated foods. Symptoms include gastroenteritis, abdominal cramps, bloody diarrhoea, fever, myalgia, headache, nausea and vomiting. In 2018, Salmonella accounted for more than half of the numbers of foodborne outbreak illnesses reported in the EU. Salmonella contamination is mostly associated with produce such as poultry, cattle and their feeds but other products such as dried foods, infant formula, fruit and vegetable products and pets have become important. Efforts aimed at controlling Salmonella are being made. For example, legislation and measures put in place reduced …

Plasma-Treated Water Affects Listeria Monocytogenes Vitality And Biofilm Structure, Oliver Handorf, Viktoria Isabella Pauker, Thomas Weihe, Uta Schnabel, Eric Freund, Sander Bekeschus, Katharina Riedel, Jörg Ehlbeck

Articles

Plasma-generated compounds (PGCs) such as plasma-processed air (PPA) or plasma-treated water (PTW) offer an increasingly important alternative for the treatment of microorganisms in hard-to-reach areas found in several industrial applications including the food industry. To this end, we studied the antimicrobial capacity of plasma-treated water on the vitality and biolm formation of Listeria monocytogenes, a common food spoilage microorganism. Using a microwave plasma (MidiPLexc), 10 ml of deionized water was treated for 100 s, 300 s and 900 s (pretreatment time) and the bacterial biolm was subsequently exposed to the PTW for 1 min, 3 min and 5 min (posttreatment …

Cold Plasma For Insect Pest Control: Tribolium Castaneum Mortality And Defense Mechanisms In Response To Treatment, Dana Ziuzina, Robin Van Cleynenbreugel, Paula Bourke

Articles

The insecticidal properties and mechanisms of high-voltage air-based atmospheric cold plasma using a contained dielectric barrier discharge reactor were investigated against Tribolium castaneum as an important bio-contaminant in stored grains spoilage. The mortality of 95.0%–100% for preadult stages can be achieved within seconds of treatment, but longer plasma exposure (5 min) is required to kill adult insects. Cold plasma treatment reduces both the respiration rate and the weight of insects and affects the levels of oxidative stress markers in adult populations. Sufficient toxicity is achievable through plasma process control in air to address the range of insect lifecycle stages that …

Plasma-Treated Water Affects Listeria Monocytogenes Vitality And Biofilm Structure, Oliver Handorf

Articles

Plasma-generated compounds (PGCs) such as plasma-processed air (PPA) or plasma-treated water (PTW) offer an increasingly important alternative for the control of microorganisms in hard-to-reach areas found in several industrial applications including the food industry. To this end, we studied the antimicrobial capacity of PTW on the vitality and biofilm formation of Listeria monocytogenes, a common foodborne pathogen.

Food Contact Surfaces: Challenges, Legislation And Solutions, Shubham Sharma, Amit Jaiswal, Brendan Duffy, Swarna Jaiswal

Articles

Food contact surfaces (FCSs) include all surfaces that may come in contact with the food during production, processing, and packaging. Food processing industries encounter several challenges due to its microbial interaction with the FCSs, such as cross-contamination of pathogenic microorganisms or allergens in food, formation of biofilm, biodeterioration of food contact surface leads to food with reduced shelf-life and quality. A legal EU framework provides the fundamental postulates for the safety and inertness of all Food Contact Materials (FCMs). Legislations have an important role in providing regulatory guidance on the quality assurance systems and verifying their implementation as a means …

The Experience Of Recovery From Childhood Sexual Abuse Among Black Men, Zeneth Myrie

Walden Dissertations and Doctoral Studies

Childhood sexual abuse (CSA) can result in consequences that are devastating and long lasting. Differences in the nature of CSA for males and females potentially influence recovery and the role of moderating factors, such as spirituality. Studies of recovery from CSA, especially men's experiences of recovery, are relatively few indicating that this is an under researched area. This lack of studies is particularly evident for ethnic minority groups. While addressing the gap in the literature, the purpose of this study was to explore the lived experience of recovery from CSA among African, Caribbean, Black identified male survivors of CSA living …

Perceptions And Instructional Practices Used By West Virginian Secondary Agricultural Teachers In Meat Science Education, Kindra D. Carr

Graduate Theses, Dissertations, and Problem Reports (ETD)

A focus on classroom integration of science, technology, engineering, and math (STEM) concepts has resulted in secondary teachers broadening the scope and delivery of STEM principles in their classes. Because agriculture classes allow students to convert abstract ideas into concrete ideas, they provide a useful setting to teach STEM concepts. Using secondary agricultural classes to teach science is effective and has contributed to higher standardized science test scores, as opposed to a science class alone. West Virginia is known for meat processing facilities and meat technology learning activities in its public schools. However, little is known about how the content …

Exploring Early Signaling Associated With Complex Stressors, Julia A. Penatzer

Graduate Theses, Dissertations, and Problem Reports (ETD)

Humans are constantly exposed to a vast number of stressors in our everyday lives from social interactions to physical activity to chemical exposures, to name a few. These stressors have significant impacts on an individual, from the cellular to whole organismal level. The body contains an intricate communication system that elicits a number of both biological and physiological responses as it attempts to maintain homeostasis. Observing these responses to stressors, can offer insight into a number of outcomes, which can be beneficial (increasing life longevity) or detrimental (leading to a disease state). By measuring specific biological adaptations at particular time …

Using Zebrafish To Elucidate The Expression And Gene Regulatory Network Of The Genomic Screen Homeobox Transcription Factors And Bring Innovative Science Learning Experiences To West Virginia, Rebecca Ann Coltogirone

Graduate Theses, Dissertations, and Problem Reports (ETD)

Central nervous system (CNS) development requires a code of regionally expressed transcription factors that impart initial neuronal cell identity, connectivity, and function. The absence of a transcription factor code would eliminate the neurodevelopmental logic producing diverse cell types in the CNS. Furthermore, early disruptions in transcription factor expression can affect later connectivity and function of neuronal circuits mediating sensory processing, defects in which are often observed as comorbid with various neurodevelopmental disorders (NDDs). Characterizing transcription factor expression and function is therefore an essential step in discerning the molecular mechanisms underlying human NDDs. genomic screen homeobox 1 and 2 (gsx1 …

Taxing Buybacks, Daniel J. Hemel, Gregg D. Polsky

Coase-Sandor Institute for Law & Economics Research Paper Series

A recent rise in the volume of corporate share repurchases has prompted calls for changes to the rules governing stock buybacks. These calls for reform are animated by concerns that buybacks enrich corporate executives at the expense of productive investment. This emerging antibuyback movement includes prominent politicians as well as academics and Republicans as well as Democrats. The primary focus of buyback critics has been on securities-law changes to deter repurchases, with only passing mention of potential tax-law solutions.

This Article critically examines the policy arguments against buybacks and arrives at a mixed verdict. On the one hand, claims that …

Regulation And Redistribution With Lives In The Balance, Daniel J. Hemel

Coase-Sandor Institute for Law & Economics Research Paper Series

A central question in law and economics is whether non-tax legal rules should be designed solely to maximize efficiency or whether they also should account for concerns about the distribution of income. This question takes on particular importance in the context of cost-benefit analysis. Federal agencies apply cost-benefit analysis when writing regulations that generate multibillion dollar impacts on the US economy and profound effects on millions of Americans’ lives. In the past, agency cost-benefit analyses typically have ignored the income-distributive consequences of those regulations. That may soon change: On his first day in office, President Biden instructed his Office of …

Visibility And Indivisibility In Resource Arrangements, Lee Anne Fennell

Coase-Sandor Institute for Law & Economics Research Paper Series

Projects like highways, bridges, pipelines, and wildlife corridors exhibit indivisibilities—we need the whole thing to have anything of value. Many environmental and social goals have a similar all-or-nothing character: staying above or below a certain critical threshold can make all the difference. This essay focuses on the role of visibility in addressing resource dilemmas that have this structure. I examine how two kinds of visibility can help avoid catastrophic consequences and advance desirable ones. The first involves recognizing when an indivisibility is present—that is, appreciating the vulnerability of resources to thresholds and cliff effects before it is too late. The …

The Law Of Restitution For Mistaken Payments: An Economic Analysis, Dhammika Dharmapala, Nuno Garoupa

Coase-Sandor Institute for Law & Economics Research Paper Series

The law of restitution and unjust enrichment has emerged as an important and independent branch of private law globally, but has attracted relatively little economic analysis. The aim of this paper is to develop a general conceptual framework for the economic analysis of the core example of restitution - mistaken payments. We develop a formal model in a parsimonious setting with two buyer-seller pairs, with low (high) transaction costs within (across) pairs. This model generates several novel insights, based on the idea that mistaken payments to strangers impose a “transaction tax” on contracting parties. It sheds new light on distortions …

Nitrite Supplementation Restores Aortic Health In Chronically Stressed Mice, Tyler Coblentz

Graduate Theses, Dissertations, and Problem Reports (ETD)

Chronic stress increases the risk of developing cardiovascular disease potentially via increases in elastic artery stiffness and endothelial dysfunction. Decreased bioavailability of the potent vasodilator nitric oxide (NO) describes a hallmark of endothelial dysfunction. Nitrite reduces into active NO, providing an alternative pathway of NO restoration. The effect of nitrite supplementation on aortic endothelial function has yet to be determined in chronically stressed mice. We hypothesized that nitrite supplementation would rescue chronic stress-attributed impairments in aortic endothelial function.

Mice at 18 weeks of age underwent an unpredictable chronic mild stress (UCMS; 5 days/week for 7 hrs/day) paradigm to elicit a …

Getting Connected: Exploring The Role Of Sustainability Labels In Tourism Marketing Communications, Elvira Kizilova

Graduate Theses, Dissertations, and Problem Reports (ETD)

While sustainability has become an important brand differentiator in many industries, current research suggests that tourism businesses rarely use sustainability labels in their communications, e.g., on their websites or other types of advertisements.

This dissertation examines the role of sustainability labels in increasing consumer preferences for sustainable travel destinations. Drawing on social exchange theory and anthropomorphism framework, we propose that sustainability labels increase consumer visit intentions, willingness to recommend a destination to someone else, and willingness to pay price premium for the sustainable offer. These effects are mediated by perception of goal congruence and connectedness with a destination. We further …

A Code Of Ethics For Gene Drive Research, George J. Annas, Chase L. Beisel, Kendell Clement, Andrea Crisanti, Stacy Francis, Marco Galardini, Roberto Galizi, Julian Grunewald, Greta Immobile, Ahmad S. Khalil, Ruth Muller, Vikram Pattanayak, Karl Petri, Ligi Paul, Luca Pinello, Alekos Simoni, Chrysanthi Taxiarchi, J. Keith Joung

Faculty Scholarship

Gene drives hold promise for use in controlling insect vectors of diseases, agricultural pests, and for conservation of ecosystems against invasive species. At the same time, this technology comes with potential risks that include unknown downstream effects on entire ecosystems as well as the accidental or nefarious spread of organisms that carry the gene drive machinery. A code of ethics can be a useful tool for all parties involved in the development and regulation of gene drives and can be used to help ensure that a balanced analysis of risks, benefits, and values is taken into consideration in the interest …

Othering Across Borders, Steven Arrigg Koh

Faculty Scholarship

Our contemporary moment of reckoning presents an opportunity to evaluate racial subordination and structural inequality throughout our three-tiered domestic, transnational, and international criminal law system. In particular, this Essay exposes a pernicious racial dynamic in contemporary U.S. global criminal justice policy, which I call othering across borders. First, this othering may occur when race emboldens political and prosecutorial actors to prosecute foreign defendants. Second, racial animus may undermine U.S. engagement with international criminal legal institutions, specifically the International Criminal Court. This Essay concludes with measures to mitigate such othering.

Race, Risk, And Personal Responsibility In The Response To Covid-19, Aziza Ahmed, Jason Jackson

Faculty Scholarship

The COVID-19 crisis has tragically revealed the depth of racial inequities in the United States. This Piece argues that the disproportion­ate impact of the pandemic on racial minorities is a symptom of a failing approach to public health, one that privileges individual behaviors over the structural conditions that generate vulnerability and inequitable health outcomes. Despite clear racial disparities in illness and deaths, the neoliberal ideology of personal responsibility shifts the onus for mitigation of risk away from the social and legal determinants of health and onto the individual. To understand how and why these disparate racial outcomes arise, this Piece …