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Investigation Of The Effect Of Silymarin On Oxidative Dna Damageand Inflammatory Markers In Ischemia/Reperfusion Injuryfollowing Experimental Testicular Torsion/Detorsion In Rats, Saadet Belhan, Serkan Yildirim, Caner Kayikci, Ahmet Ufuk Kömüroğlu, Uğur Özdek, Yağmur Kuşcu

Turkish Journal of Zoology

The aim of the present study was to clarify the effects of silymarin on experimental testicular ischemia / reperfusion injury. A total of 40 Wistar albino rats (10-12 weeks of age, weighing 280-300 g) were randomly divided into five groups. Control group: No surgical procedures were performed. Torsion 3 h / detorsion 3 h group; torsion 3 h / detorsion 24 h group; torsion 3 h / detorsion 3 h + silymarin (250 mg/kg) group; and torsion 3 h / detorsion 24 h + silymarin (250 mg/kg) group. In the study, 720° torsion was applied to the left testicle. At …

A Study On The Pupal Development Of Calliphora Vomitoria (L., 1758) (Calliphoridae: Diptera) At Different Temperatures, Osman Sert, Ceyda Ergi̇l

Turkish Journal of Zoology

In this study, the pupal development process of the Calliphora vomitoria (L. 1758), widely used in the estimation of postmortem time in forensic entomology, was examined. In the last decade, studies of the development periods in the pupal stage and the development times of these periods have increased around the world and specifically in Turkey. In this study, the aim was to detect the pupal development periods of the Calliphora vomitoria via a process of hourly pupal dissection, a process that would be the only one of its kind in the literature for this species. This method was repeated under …

What Are You Doing Here? Investigating On An Unexpected Association In Shallow Mediterranean Dark Caves Sheds Light On The Diet Of Marionia Blainvillea (Mollusca, Gastropoda, Nudibranchia), Egidio Trainito, Marco Fantin, Elisa Manganelli, Giulia Furfaro

Turkish Journal of Zoology

In a shallow dark cave along the coast of Capo Palinuro (Campania, Italy), the finding of an unusual aggregation of individuals belonging to Marionia blainvillea (Gastropoda, Nudibranchia) has allowed to identify a population of Cervera atlantica (Cnidaria, Anthozoa, Alcyonacea) and to add this latter to the list of the hosts preyed by this tritoniid nudibranch. This association was confirmed by a second observation in a dark shallow cave in the Island of San Pietro (Sardinia, Italy). Moreover, a subsequent internet data mining shed light on the diet of M. blainvillea adding useful ecological notes on the scarcely known trophism characterizing …

Playing At The Crossroads Of Religion And Law: Historical Milieu, Context And Curriculum Hooks In Lost & Found, Owen Gottlieb

Articles

This chapter presents the use of Lost & Found – a purpose-built tabletop to mobile game series – to teach medieval religious legal systems. The series aims to broaden the discourse around religious legal systems and to counter popular depiction of these systems which often promote prejudice and misnomers. A central element is the importance of contextualizing religion in period and locale. The Lost & Found series uses period accurate depictions of material culture to set the stage for play around relevant topics – specifically how the law promoted collaboration and sustainable governance practices in Fustat (Old Cairo) in twelfth-century …

Stinktree No. 1, 1972

Shelby County, Tennessee

"Stinktree Number 1", a poetry journal published by Thomas Johnson in Memphis, Tennessee, in February 1972. Issues 1-3 were published in Memphis between 1972 and 1973 before moving to Ithaca, New York. No. 5 was the last issue.

Plaster Creek Floodplain And Adjacent Ravines Near Stanaback Park: Botanical Inventory Highlights And Management Considerations, David Warners, Garrett Crow, Haley Weesies

Faculty and Professional Research

In the summer of 2021, the research team visited this area of ravines and floodplain a total of twenty-one times to conduct our field research. During the visits, they carefully walked throughout different sections of the study site, identifying each vascular plant species they saw growing there and observing how the flora developed throughout the season. In addition to keeping detailed field notes, they documented permanent records of the findings of our inventory by collecting voucher specimens that have been deposited in the Calvin University Herbarium. Additionally, they sent duplicate specimens to the Michigan State University Herbarium and/or University of …

Retheorizing Precedent, Randy J. Kozel

Journal Articles

Does the doctrine of stare decisis support judicial attempts to retheorize dubious precedents by putting them on firmer footing? If it does, can retheorization provide a means for Chevron to endure as a staple of administrative law notwithstanding serious challenges to its established rationale?

The Mischief Rule, Samuel L. Bray

Journal Articles

The mischief rule tells an interpreter to read a statute in light of the “mischief” or “evil”—the problem that prompted the statute. The mischief rule has been associated with Blackstone’s appeal to a statute’s “reason and spirit” and with Hart-and-Sacks-style purposivism. Justice Scalia rejected the mischief rule. But the rule is widely misunderstood, both by those inclined to love it and those inclined to hate it. This Article reconsiders the mischief rule. It shows that the rule has two enduringly useful functions: guiding an interpreter to a stopping point for statutory language that can be given a broader or narrower …

Clpxp Degradation System In Escherichia Coli, A Study Of Its Energy Sources And Its Applications In Managing The Expression Levels Of Targeted Membrane And Soluble Proteins, Thilini Abeywansha

Theses and Dissertations--Chemistry

ClpXP is an Escherichia coli protease that carries out energy-dependent intracellular proteolysis. In recent years, this system has been widely studied due to its importance as protein regulatory machinery and a virulence factor. Protein substrates of ClpXP contain degrons with a specific protein sequence. SsrA tag is one of the five degrons known to designate proteins for ClpXP degradation. SsrA is an 11 amino acid peptide added to the C-terminus of nascent polypeptide chains translated from aberrant messenger RNAs lacking stop codons via a process called trans-translation.

ClpXP was known to targets only cytosolic proteins with degrons until recently, …

Rational Design Of Small Molecule Disruptors Of Protein-Protein Interactions: Pd-1/Pd-L1; C-Myc, Arid4b, Samuel Ofori

Theses and Dissertations--Chemistry

Protein-protein interactions (PPIs) are vital to many biological processes, including gene expression, and immune reactions to pathogens. There are approximately 650,000 PPIs in humans with pertinent physiological functions. Aberrant expression of PPIs lead to improper function and contribute to a plethora of disease conditions including cancer. Thus, PPIs represent an enormous target space for drug discovery and chemical probes. Direct targeting of clinically relevant PPIs with small molecules remains an unmet medical need. Development of small-molecule inhibitors of PPIs is a challenging enterprise and in most cases considered undruggable due to large protein surfaces, lack of deep binding pockets and …

Investigation Of Multidrug Efflux Transporter Acrb In Escherichia Coli: Assembly, Degradation And Dynamics, Prasangi Irosha Rajapaksha

Theses and Dissertations--Chemistry

The Resistant Nodulation Division (RND) super family member, tripartite AcrA-AcrB-TolC efflux pump, is a major contributor in conferring multidrug-resistance in Escherichia coli. The structure of the pump complex, and drug translocation by functional rotation mechanism have been widely studied. Despite of all these data, the dynamics of the assembly process of the pump and AcrB during functional rotation in the process of drug efflux remains poorly understood. My thesis focuses on understanding the pump assembly process, dynamics of AcrB in functional rotation mechanism, and also investigate the mechanism of degradation of AcrB facilitated by a C-terminal ssrA tag.

In the …

Flooding Their Mailbox: Recommendations For Notifying Residents Of Changes To Fema Flood Maps, Andrew Major, Alston Underwood

Virginia Coastal Policy Center

No abstract provided.

A Quick Guide To Resilience, Virginia Coastal Policy Center, William & Mary Law School

Virginia Coastal Policy Center

The Virginia Coastal Policy Center (VCPC) developed this Guide as a reference for citizens and local governments in Virginia. The Guide also may be used as a resource by local governments as they use the PREP (Planning for Resilience: Evaluation and Prioritization) Tool discussed.

Differential Mechanisms Linking Early Childhood Violence Exposure And Social/Environmental Deprivation To Adolescent Conduct Problems: Exploration Of A Gene-By-Environment Interaction, Samantha R. Awada

Graduate Research Theses & Dissertations

The dimensional model of adversity and psychopathology (DMAP) posits dimensions of childhood adversity (i.e., deprivation, violence exposure) differentially predict child neurobiological outcomes and behavioral correlates of these neurobiological outcomes. Both deprivation and violence exposure are associated with higher child conduct problems. Genetic and environmental vulnerability factors often interact to increase or decrease risk for developing adolescent conduct problems. One gene of particular interest is COMT, which is implicated in the dopaminergic system. The present study explored whether dimensions of childhood adversity during the child’s first five years of life interacted with COMT genotype to differentially confer cognitive (i.e., executive dysfunction) …

Dominance Or Leverage? An Analysis Of Female Power In Captive Varecia, Jessie E. Birckelbaw

Graduate Research Theses & Dissertations

Lemurs are unusual in that, unlike in most other primates, females have more power than males. This is evident by females receiving priority access to foods and preferred spaces, and frequent grooming. Rebecca Lewis provided a framework to analyze the basis of female power that distinguishes between true dominance and leverage. Dominance is defined as the physical ability to overpower an individual, whereas leverage is the ability to influence others based on intangible resources, such as social currency like grooming or the potential for mating. This study aimed to investigate female power in the critically endangered ruffed lemurs (genus Varecia). …

Their Lessons: Inspiring Stories Of Ten Retired African American Volunteers Serving The Augusta, Georgia, Community, Gwendolyn Bentley Clayborne

Graduate Research Theses & Dissertations

African Americans found ways to respond to the needs of their communities as volunteers when they were denied many services available to Whites citizens. Opportunities to volunteer were provided both formally and informally through churches, sororities, fraternities and other organizations. Many families would not have been able to afford care for their children and/or elderly family members had it not been for other members of their family and friends volunteering to provide the needed services. Growing up in the early fifties, before starting to school, my first caregiver was Mr. Allen, an elderly man. His wife, who worked from home …

Correctional Education As Therapeutic Change: Exploring The Use Of Animal-Assisted Therapy Programs With Incarcerated Women, Terrie Ciez

Graduate Research Theses & Dissertations

Throughout history and in every culture and country, animals and humans have formed special bonds often as pets. Well trained pets have often been used in Animal Assisted Therapy (AAT) programs in hospitals and nursing homes to help patients cope with illnesses and recovery while away from home. Pet visits to these facilities have documented reductions in medications, stress, and loneliness when a simple wet nose reaches on to a patient’s bed for attention. A variety of animals have been incorporated into various facilities ranging from birds, fish tanks, and puppies and kittens to relieve the stress of residents. A …

The Political Utility Of Poetry In Aristotle’S Thought, Stephen Eugene Clouse

Graduate Research Theses & Dissertations

Aristotle’s political thought asks the serious student of politics to examine critically the way we use our leisure (σχολη) in the life of the city. This project aims at such a critical examination by exploring the relationship between poetry and the city. The task here is not to understand the political commentary of a specific poetic work but to understand the way that poetry has a use in the life of the city. Traditionally this relationship is explored through piety but I argue that Aristotle rejects this foundation and grounds the usefulness of poetry in how we learn mimetically. Because …

Virtual Group Advising: Engaging In Alternative Advising Strategies To Support Students Amid A Global Pandemic, Bethany Geiseman

Graduate Research Theses & Dissertations

Considering the evolving needs of non-traditional students and the impact of the Covid-19 pandemic, it has become more critical to explore the use of technology in advising. This study aimed to explore the experiences of students who participated in virtual group advising and examined the dynamics of this virtual group setting related to student preparedness and engagement. Three themes that emerged during data analysis were a) increased feelings of academic preparedness, b) increased social interaction among peers during and after advising, and c) positive perceptions of using technology during advising. This study found that while virtual group advising may not …

Characterization Of Potential Anti-Infective Agents By Targeting Burkholderia Pseudomallei And Escherichia Coli Ispf, Dakota Lane Grote

Graduate Research Theses & Dissertations

With the likelihood of contracting an antibiotic resistant infection increasing, the need for novel anti-infective agents is critical. The development of novel anti-infective agents benefits from the identification of new target pathways necessary for the survival of the pathogen. One such target is the methylerythritol phosphate (MEP) pathway, responsible for the synthesis of the isoprenoid precursors isopentyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) in bacteria and other pathogenic organisms. The MEP pathway is an attractive target because it is specific to a wide range of pathogenic organisms, while humans have a separate pathway, the mevalonate (MVA) pathway, for the biosynthesis …

Herlands: Imperial Feminisms From Charlotte Perkins Gilman To Wonder Woman, Anna Jankovsky

Graduate Research Theses & Dissertations

The society of women is a trope of feminist utopian fiction in which a group of women live together in harmony without the influence of men to disrupt their society. This trope functions on five criteria: 1) The society must be able to defend itself and replenish itself without the assistance of men. 2) It must be fully isolated and nearly impenetrable from the outside world 3) It must have a utopic order of society untroubled by ambition. 4) It must be infiltrated and challenged by a man during the course of the story. 5) It must grapple with the …

The Making Of Monsters: Creativity And Morality In Gothic Novels Frankenstein And The Picture Of Dorian Gray, Elisa Klaassen

Graduate Research Theses & Dissertations

This study examined Mary Shelley’s Frankenstein, which foreshadows the Victorian period, and Oscar Wilde’s The Picture of Dorian Gray, which reflects on it. The two novels are both monster stories that share many similarities, including themes of creativity and morality. However, the two novels are distinctly different in surprising ways. This thesis serves as an examination of their differing treatments of creativity and morality. In its examination, it reveals the ways in which Shelley couples these themes, foreshadowing Victorianism, while Wilde decouples them, reflecting and refracting on Victorian themes. Thus, this study reveals some of the major cultural changes that …

Testing A Global Standard For Quantifying Species Recovery And Assessing Conservation Impact, Molly K. Grace, John Carroll, 201 Other Scholars

School of Biological Sciences: Faculty Publications

Recognizing the imperative to evaluate species recovery and conservation impact, in 2012 the International Union for Conservation of Nature (IUCN) called for development of a “Green List of Species” (now the IUCN Green Status of Species). A draft Green Status framework for assessing species’ progress toward recovery, published in 2018, proposed 2 separate but interlinked components: a standardized method (i.e., measurement against benchmarks of species’ viability, functionality, and preimpact distribution) to determine current species recovery status (herein species recovery score) and application of that method to estimate past and potential future impacts of conservation based on 4 metrics ( …

Medical Cannabis And Counselor Education: Examining The Relationship Between Counselor Education Curriculum And The Incorporation Of Medical Cannabis, Anne Catherine Adrian

Graduate Research Theses & Dissertations

The focus of this study was to examine the status of medical cannabis instruction in counselor education curriculum programs. There is evidence to indicate that medical cannabis use may be beneficial in mental health care. However, there is limited research on medical cannabis in counselor education. The following research questions provided a framework of investigation for this study: What is the status of the inclusion of medical cannabis content in counselor education curriculum programs and what are the plans to incorporate this content in the future?

In this study, a non-experimental design was used to describe or examine associations between …

Relationship Between Student Personality Traits And Continuance Intention To Use Massive Open Online Courses (Moocs), Rakez Mahmoud Al-Ararah

Graduate Research Theses & Dissertations

Recently, Massive Open Online Courses (MOOCs) have started to play an important role in e-learning initiatives and have become increasingly popular among e-learning communities. However, the dropout rates of students in MOOCs have become an issue that needs to be studied by MOOC providers, researchers, practitioners, and stakeholders (Daneji, Ayub, & Khambari, 2019). The current study employed the Five-Factor Model (FFM), and the Expectation-Confirmation Model (ECM) to examine the effect of personality traits on learners’ continuance intention to use MOOCs via Edraak in Jordan. This study also explored gender differences in the posited relationships.An online survey was distributed to 6,000 …

The Transcorporeal South: Bodies And Ecologies In Twentieth-Century Southern Literature, Tiffany Morgan Messick

Graduate Research Theses & Dissertations

This dissertation proposes that transcorporeality offers an alternative to Cartesian dualistic modes of embodiment in Walker Percy’s, The Moviegoer, Zora Neale Hurston’s, Their Eyes Were Watching God, Richard Wright’s, Native Son, and Carson McCullers’s The Heart is a Lonely Hunter. Opposing the division between mind and body as theorized by René Descartes, transcorporeality advances the body’s porosity, maintaining that the individual is enmeshed within the material world and that this entanglement consubstantiates consciousness. Examining the works of Descartes, focusing especially on the ways that Cartesian ideas have been applied in Southern culture, I contend that a Cartesian definition of subjectivity, …

The Influence Of Resting Metabolic Rate And Environment On Tonic Immobility In A Parasitoid Wasp (Hymenoptera: Pteromalidae), Ryan D. Morris

Graduate Research Theses & Dissertations

The effects of RMR (resting metabolic rate) and environment on tonic immobility were examined in the parasitoid wasp Spalangia cameroni (Order Hymenoptera: Family Pteromalidae). Tonic immobility (TI) is described as a state that an organism enters wherein they fall onto their back or side and become immobile for a period of time when disturbed. This state can last for several seconds to a few hours, depending on the organism in question. The organism may be aware during this period of time but unable to move. Female wasps were subjected to experimental treatments that involved manipulation of their environment, specifically, cold …

Reflections From Gifted Students: A Qualitative Study Examining Social-Emotional Development In Relation To Social Justice-Oriented Citizenship, Margo A. Nauert

Graduate Research Theses & Dissertations

Gifted students have unique social-emotional needs that are amplified through their heightened sensitivities or overexcitabilities. Common traits that gifted students exhibit in addition to their social-emotional needs are similar to those needed for the optimal level of citizenship, the justice-oriented citizen. This qualitative study asked a convenience sample of gifted students to reflect on their social-emotional development and overexcitabilities and how their gifted traits have begun to prepare them for justice-oriented citizenship.To gather data to be coded, nine incoming 7th grade students in a gifted program were recruited from a self-contained gifted program. These students participated in this study by …

A Qualitative Evaluation Of A Pre-College Summer Program: The Research Apprentice Program, Stanford B. Oglesby Iii

Graduate Research Theses & Dissertations

The Research Apprentice Program is a pre-college, summer enrichment program that seeks to recruit underrepresented students into the field of agriculture and the College of ACES at the University of Illinois. The program has been in operation for more than thirty years and has reported many successes. Among these successes are a recruitment rate of 55% and a graduation rate of 96%. This program has yet to be formally evaluated. This study was conducted to provide a formative evaluation of the program to assess if the intended outcomes of the administrative participants are consistent with the lived experiences of the …

Longitudinal And Concurrent Contributions Of Verbal And Physical Scaffolding To Toddlers’ Inhibitory Control, Anton Petrenko

Graduate Research Theses & Dissertations

Executive function (EF) is crucial to lifespan development and environmental factors have been found to impact its development. Previous research has shown that parenting can make meaningful impacts on children’s EF, with scaffolding receiving broad support. Scaffolding refers to an adult’s ability to guide a child through a challenging task without providing too much or too little support. However, many of the studies which have examined scaffolding have been done in preschool- and school-aged samples, with limited research conducted in younger samples. Very few studies have separately examined verbal and physical components of scaffolding, which may differentially contribute to children’s …