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Crouching Tiger Cello Concerto - A Melding Of Form And Content For The Concert Stage, Xiaohang Yu

Theses and Dissertations--Music

Tan Dun’s Crouching Tiger Concerto for Amplified Cello and Orchestra is not only one of the most frequently performed cello concerto of the recent past; it also demonstrates Tan’s masterful synthesis of artistic forms from the Chinese and the Western art music traditions with visual media that extends beyond the concert-hall. The music for this concerto was initially composed as part of the score for Ang Lee’s film Crouching Tiger, Hidden Dragon, itself a landmark blend of Chinese cinema with Western technique. The score broke boundaries, combining Western orchestral music with traditional Chinese instruments and thematic material. This melding …

A Hydrologic Study Of Climate Variability In Arid Region, Abdullah Alzaydani

Electronic Theses and Dissertations

Climate variability is an important subject to study. It is the change of climate over a long time, which could have a positive or negative impact on humans, soil, and wildlife. Many environments, such as arid environment could be affected by climate variability. The research goal is studying and examining climate variability in arid environment. The research includes three different studies. The first study includes reviewing and understanding of climate variability over extended time through existing studies in arid environments. In addition, this study includes knowledge about climate negative or positive impact on the environment. This study will be reviewing …

Free-Living Diazotrophs And The Nitrogen Cycle In Natural Grassland Revealed By Culture Dependent And Independent Approaches, Amrit Koirala

Electronic Theses and Dissertations

Biological nitrogen fixation contributes to half of the global supply of nitrogen to the biosphere. It is carried out by a diverse group of prokaryotes called diazotrophs via the nitrogenase enzyme. Nitrogen fixation research is focused on the narrow group of symbiotic diazotrophs, and the vast majority of free-living diazotrophs which contribute significantly to fixed nitrogen are yet to be explored. The goal of this research was to access phylogeny of diazotrophs considering the most up-to-date genomic information and apply that knowledge to understand the diversity of free-living diazotrophs in a natural grassland ecosystem, both by culture dependent and independent …

Synthesis Of Intracellular And Extracellular Gold Nanoparticles With A Green Machine And Its Antifungal Activity, Nurbanu Gürsoy, Betül Yilmaz Öztürk, İlknur Dağ

Turkish Journal of Biology

Green synthesis method is being increasingly used in the development of safe, stable, and eco-friendly nanostructures with biological resources. In this study, extracellular and intracellular synthesis of gold nanoparticles (AuNPs) was carried out using green algae Chlorella sorokiniana Shihira & R.W. Fresh algae were isolated and identified from Musaözü Pond located in the province of Eskişehir and then extraction process were performed. Optimization studies were studied using pH value, metal salt concentration, and time parameters for extracellular synthesis and using only time parameter for intrasellular synthesis. Since more controlled and optimum conditions can be achieved in the production of AuNPs …

Il-1r1 Deficiency Impairs Liver Regeneration After 2/3 Partial Hepatectomy In Aged Mice, Deming Li, Ze Wang, Chunyan Zhang, Cunshuan Xu

Turkish Journal of Biology

Inflammation has a dual effect: it can protect the body and destroy tissue and cell as well. The purpose of this experiment was to determine the role of IL-1R1 in liver regeneration (LR) after partial hepatectomy (PH) in aged mice. The wild-type (WT, n = 36) and the IL-1R1 knockout (KO, n = 36) 24-month-old C57BL/6J mice underwent two-thirds PH; 33 WT mice underwent sham operation. Liver coefficient was calculated by liver/body weight. The mRNA and protein expressions of genes were evaluated by quantitative realtime polymerase chain reaction (qRT-PCR) and Western blotting methods, respectively. Compared with WT mice, liver coefficient …

Lipase From New Isolate Bacillus Cereus Ata179: Optimization Of Production Conditions, Partial Purification, Characterization And Its Potential In The Detergent Industry, Eli̇f Demi̇rkan, Aynur Aybey Çeti̇nkaya, Maoulida Abdou

Turkish Journal of Biology

In this study, 341 Bacillus sp. strains were isolated from agricultural soils of Turkey. The potent extracellular lipase producer was selected. It was identified by 16S rRNA, named as Bacillus cereus ATA179. Optimal nutritional and physical parameters for lipase production were determined. Sucrose as the carbon source, (NH4)2HPO4 as the nitrogen source, CaCl2 as the metal ion were obtained. The best results of physical parameters were stated at 45°C, pH 7.0, shaking rate 50 rpm, inoculation amount 7% and inoculum age 24 h. ATA179 strain showed a 51% increase in enzyme production in the modified medium created by optimizing nutritional …

Characteristics And Clinical Significance Of Cd163+/Cd206+M2 Mono-Macrophage In The Bladder Cancer Microenvironment, Xiangjie Kong, Ming Zhu, Zhirong Wang, Zhuoqun Xu, Jianfeng Shao

Turkish Journal of Biology

The tumor microenvironment may recruit monocytes, with a protumoral macrophage phenotype (M2) that plays an important role in solid tumor progression and metastasis. Therefore, it is necessary to understand the characteristics of these cells for cancer prevention and treatment. Bladder cancer tissue samples and paracarcinoma tissues samples were collected, and the expression of CD163+ cells in tumor tissues was observed. Then, we observed the expression of infiltrating CD45+CD14+CD163+ cell subset and analyzed the molecular expressions related to immunity and angiogenesis. C57/BL6 mice were inoculated subcutaneously, and dynamic changes of CD11b+F4/80+CD206+ mononuclear macrophages expression for tumor-bearing mice were detected. The results …

Investigation Of Neuro-Inflammatory Parameters In A Cuprizone Induced Mouse Model Of Multiple Sclerosis, Ti̇muçi̇n Avşar, Gökçe Erdem, Gökhan Terzi̇oğlu, Eda Tahi̇r Turanli

Turkish Journal of Biology

Cuprizone, copper chelator, treatment of mouse is a toxic model of multiple sclerosis (MS) in which oligodendrocyte death, demyelination and remyelination can be observed. Understanding T and B cell subset as well as their cytokines involved in MS pathogenesis still requires further scrutiny to better understand immune component of MS. The study presented here, aimed to evaluate relevant cytokines, lymphocytes, and gene expressions profiles during demyelination and remyelination in the cuprizone mouse model of MS. Eighty male C57BL/6J mice fed with 0.2% cuprizone for eight weeks. Cuprizone has been removed from the diet in the following eight weeks. Cuprizone treated …

Classification Of Bladder Cancer Cell Lines According To Regulon Activity, Aleyna Eray, Serap Erkek Özhan

Turkish Journal of Biology

Bladder cancer is one of the most frequent cancers and causes more than 150.000 deaths each year. During the last decade, several studies provided important aspects about genomic characterization, consensus subgroup definition, and transcriptional regulation of bladder cancer. Still, much more research needs to be done to characterize molecular signatures of this cancer in depth. At this point, the use of bladder cancer cell lines is quite useful for the identification and test of new signatures. In this study, we classified the bladder cancer cell lines according to the activities of regulons implicated in the regulation of primary bladder tumors. …

Fluid Shear Stress And Endothelial Cells Synergistically Promote Osteogenesis Of Mesenchymal Stem Cells Via Integrin Ss1-Fak-Erk1/2 Pathway, Mingli Jiang, Qihua Shen, Yi Zhou, Wenxia Ren, Miaomiao Chai, Yan Zhou, Wen-Song Tan

Turkish Journal of Biology

Prevascularization and mechanical stimulation have been reported as effective methods for the construction of functional bone tissue. However, their combined effects on osteogenic differentiation and its mechanism remain to be explored. Here, the effects of fluid shear stress (FSS) on osteogenic differentiation of rat bone-marrow-derived mesenchymal stem cells (BMSCs) when cocultured with human umbilical vein endothelial cells (HUVECs) were investigated, and underlying signaling mechanisms were further explored. FSS stimulation for 1-4 h/day increased alkaline phosphatase (ALP) activity and calcium deposition in coculture systems and promoted the proliferation of cocultured cells. FSS stimulation for 2 h/day was selected as the optimized …

A Cytoplasmic Escapee: Desmin Is Going Nuclear, Ecem Kural Mangit, Ni̇lüfer Düz, Pervi̇n Ruki̇ye Di̇nçer

Turkish Journal of Biology

It has been a long time since researchers have focused on the cytoskeletal proteins' unconventional functions in the nucleus. Subcellular localization of a protein not only affects its functions but also determines the accessibility for cellular processes. Desmin is a muscle-specific, cytoplasmic intermediate filament protein, the cytoplasmic roles of which are defined. Yet, there is some evidence pointing out nuclear functions for desmin. In silico and wet lab analysis shows that desmin can enter and function in the nucleus. Furthermore, the candidate nuclear partners of desmin support the notion that desmin can serve as a transcriptional regulator inside the nucleus. …

Sex-Related Differences In Murine Models Of Chemically Induced Pulmonary Fibrosis, Pavel Solopov, Ruben Manuel Luciano Colunga Biancatelli, Christiana Dimitropoulou, John D. Catravas

Bioelectrics Publications

We developed two models of chemically induced chronic lung injury and pulmonary fibrosis in mice (intratracheally administered hydrochloric acid (HCl) and intratracheally administered nitrogen mustard (NM)) and investigated male-female differences. Female mice exhibited higher 30-day survival and less weight loss than male mice. Thirty days after the instillation of either HCl or NM, bronchoalveolar lavage fluid displayed a persistent, mild inflammatory response, but with higher white blood cell numbers and total protein content in males vs. females. Furthermore, females exhibited less collagen deposition, milder pulmonary fibrosis, and lower Ashcroft scores. After instillation of either HCl or NM, all animals displayed …

Age-Dependent Chronic Lung Injury And Pulmonary Fibrosis Following Single Exposure To Hydrochloric Acid, Ruben M.L. Colunga Biancatelli, Pavel Solopov, Christiana Dimitropoulou, John D. Catravas

Bioelectrics Publications

Exposure to hydrochloric acid (HCl) represents a threat to public health. Children may inhale higher doses and develop greater injury because of their smaller airways and faster respiratory rate. We have developed a mouse model of pediatric exposure to HCl by intratracheally instilling p24 mice (mice 24 days old; 8–10 g) with 2 µL/g 0.1 N HCl, and compared the profile of lung injury to that in HCl-instilled adults (10 weeks old; 25–30 g) and their age-matched saline controls. After 30 days, alveolar inflammation was observed with increased proteinosis and mononuclear cells in the bronchoalveolar lavage fluid (BALF) in both …

Chimurenga Chepfungwa: A Liberated Cultural Curriculum For The Madzimbabwe Singer, Tanyaradzwa Tawengwa

Theses and Dissertations--Music

Chimurenga ChePfungwa is the self-liberation of the mind. Education can either be an instrument for liberation or a tool for colonial indoctrination, brainwashing, and enslavement — the European colonization of Africa in the late-nineteenth century and the continent's epic efforts at self-liberation have amply taught us this.

Chimurenga ChePfungwa calls for the centering of ChiVanhu knowledge systems such as Ngano, Tsumo neNziyo. ChiVanhu encapsulates Madzimbabwe indigenous knowledge systems, cosmologies, and ways of being, and this paper insists on the primacy of these ChiVanhu epistemologies for the construction of knowledge and knowing.

Amagama ayadala. Words create. So much of the language …

The Relationship Between Nostalgia, Life Meaningfulness, And Distress Tolerance Within A Chronic Pain Population, Samantha Lyon

PCOM Psychology Dissertations

Nostalgia, defined as a bittersweet longing for the past, has been found to buffer against existential threats through increasing perception of meaning in life (MIL). MIL consists of subconstructs including coherence, significance, and purpose. The relationship between nostalgia and the subconstructs of MIL has not been fully established and which MIL component(s) nostalgia affects is unknown. The primary objective of this study was to better understand the relationship between nostalgia and components of MIL as well as psychological wellness within a chronic pain population. It was hypothesized that participants high in trait nostalgia would have a higher overall MIL score …

Resources For Higher Education Faculty: Development Of The Growth Mindset Curriculum For College Instructors, Angela Gwathney

PCOM Psychology Dissertations

Student’s implicit theories of intelligence within higher education influences their academic performance. A two-part study was conducted to assess educator’s implicit theory of intelligence within high academia. Participants in Study 1 included instructors within higher education institutions who have been administered a Google survey inquiring about their teaching pedagogies, personal characteristics, and demographic. Results indicated that faculty, in general, hold a growth mindset about their students but also hold some fixed mindset beliefs. In addition, there were few differences between instructors from Community Colleges vs Four-Year Institutions or between Public vs Private Institutions. These results suggest that students are no …

Examining Physicians’ Attitudes And Knowledge Regarding Medical Marijuana, Philip Kaplan

PCOM Psychology Dissertations

Marijuana is one of the most commonly used illicit substances in the U.S. and its rapid implementation as a form of treatment has sparked significant national attention and debate among clinicians. In the United States, medical marijuana (MM) may be recommended as a form of treatment by certified physicians. The purpose of this study was to examine licensed physicians’ support for recommending MM for various health conditions, their perceived knowledge regarding its efficacy as treatment, and their attitudes toward MM. This study employed a correlational design utilizing a self-administered, online survey (PCOM REDCap) to collect quantitative information from licensed and …

Effects Of Bradykinin On Proliferation, Apoptosis, And Cycle Of Glomerular Mesangial Cells Via The Tgf-Ss1/Smad Signaling Pathway, Ji Dong, Li Ding, Liuwei Wang, Zijun Yang, Yulin Wang, Ying Zang, Xuexia Cao, Lin Tang

Turkish Journal of Biology

We aimed to assess the effects of bradykinin (BK) on the proliferation, apoptosis, and cycle of glomerular mesangial cells via the transforming growth factor-ß 1 (TGF-ß1)/Smad signaling pathway. Rat glomerular mesangial cells, HBZY-1, were divided into normal group (untreated), model group (5 ng/L TGF-ß1), BK group (5 ng/L TGF-ß1 + 1 ng/L BK), and inhibitor group [5 ng/L TGF-ß1 + 1 ng/L LY2109761 (TGF-ß1-specific inhibitor)]. The cell proliferation, cycle, apoptosis, expression of type I collagen (Col-1), and protein expressions of Col-1, TGF-ß1, and phosphorylated Smad2 (p-Smad2) were detected by EdU labeling, flow cytometry, acridine orange/ethidium bromide (AO/EB) dual staining, immunofluorescence …

Increased Ribonuclease Activity In Solanum Tuberosum L. Transformed With Heterologous Genes Of Apoplastic Ribonucleases As A Putative Approach For Production Of Virus Resistant Plants, Andrii Potrokhov, Daria Sosnovska, Olga Ovcharenko, Irena Budzanivska, Volodymyr Rudas, Mykola Kuchuk

Turkish Journal of Biology

Viral pathogens seriously decrease the yield of potato (Solanum tuberosum L.) -an important agricultural crop. Therefore, there is a demand for potato cultivars resistant to multiple viruses. Ribonucleases (RNases) are supposed to be engaged to antiviral response in plants. Heterologous RNase gene expression provides a tool for production of cultivars with multiple resistance to viruses and viroids. Transgenic potato cultivars Luhivs'ka and Lasynak with heterologous genes bov and ZRNase II of apoplastic RNases from Bos taurus and Zinnia elegans respectively were obtained via Agrobacterium-mediated transformation. The presence of bov and ZRNase II transgenes was confirmed by PCR analysis. RNase activity …

An Update Comprehensive Review On The Status Of Covid-19: Vaccines, Drugs, Variants And Neurological Symptoms, Ebru Özkan Oktay, Sali̇h Tuncay, Tuğba Kaman, Ömer Faruk Karasakal, Öznur Özge Özcan, Tuğçe Soylamiş, Mesut Karahan, Muhsi̇n Konuk

Turkish Journal of Biology

Various recently reported mutant variants, candidate and urgently approved current vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many current situations with severe neurological damage and symptoms as well as respiratory tract disorders have begun to be reported. In particular, drug, vaccine, and neutralizing monoclonal antibodies (mAbs) have been developed and are currently being evaluated in clinical trials. Here, we review lessons learned from the use of novel mutant variants of the COVID-19 virus, immunization, new drug solutions, and antibody therapies for infections. Next, we focus on the B 1.1.7, B 1.351, P.1, and B.1.617 lineages or variants of …

Neuropathy In Covid-19 Associated With Dysbiosis-Related Inflammation, Busra Aktas, Belma Aslim

Turkish Journal of Biology

Although COVID-19 affects mainly lungs with a hyperactive and imbalanced immune response, gastrointestinal and neurological symptoms such as diarrhea and neuropathic pains have been described as well in patients with COVID-19. Studies indicate that gut-lung axis maintains host homeostasis and disease development with the association of immune system, and gut microbiota is involved in the COVID-19 severity in patients with extrapulmonary conditions. Gut microbiota dysbiosis impairs the gut permeability resulting in translocation of gut microbes and their metabolites into the circulatory system and induce systemic inflammation which, in turn, can affect distal organs such as the brain. Moreover, gut microbiota …

Targeting Cov-2 Spike Rbd And Ace-2 Interaction With Flavonoids Of Anatolian Propolis By In Silico And In Vitro Studies In Terms Of Possible Covid-19 Therapeutics, Hali̇l İbrahi̇m Güler, Fulya Ay Şal, Zehra Can, Yakup Kara, Oktay Yildiz, Ali̇ Osman Beldüz, Sabri̇ye Çanakçi, Sevgi̇ Kolayli

Turkish Journal of Biology

Propolis is a multi-functional bee product rich in polyphenols. In this study, the inhibitory effect of Anatolian propolis against SARS-coronavirus-2 (SARS-CoV-2) was investigated in vitro and in silico. Raw and commercial propolis samples were used, and both samples were found to be rich in caffeic acid, p-coumaric acid, ferulic acid, t-cinnamic acid, hesperetin, chrysin, pinocembrin, and caffeic acid phenethyl ester (CAPE) at HPLC-UV analysis. Ethanolic propolis extracts (EPE) were used in the ELISA screening test against the spike S1 protein (SARS-CoV-2): ACE-2 interaction for in vitro study. The binding energy values of these polyphenols to the SARS-CoV-2 spike and ACE-2 …

The Potential Use Of Drosophila As An In Vivo Model Organism For Covid-19-Related Research: A Review, Eşref Demi̇r

Turkish Journal of Biology

The world urgently needs effective antiviral approaches against emerging viruses, as shown by the coronavirus disease 2019 (COVID-19) pandemic, which has become an exponentially growing health crisis. Scientists from diverse backgrounds have directed their efforts towards identifying key features of SARS-CoV-2 and clinical manifestations of COVID-19 infection. Reports of more transmissible variants of SARS-CoV-2 also raise concerns over the possibility of an explosive trajectory of the pandemic, so scientific attention should focus on developing new weapons to help win the fight against coronaviruses that may undergo further mutations in the future. Drosophila melanogaster offers a powerful and potential in vivo …

Determination Of The Interaction Between The Receptor Binding Domain Of 2019-Ncov Spike Protein, Tmprss2, Cathepsin B And Cathepsin L And Glycosidic And Aglycon Forms Of Some Flavonols, Erman Sali̇h İsti̇fli̇, Arzuhan Şihoğlu Tepe, Paulo Augusto Netz, Cengi̇z Sarikürkcü, İbrahi̇m Hali̇l Kiliç, Bektaş Tepe

Turkish Journal of Biology

The novel coronavirus (COVID-19, SARS-CoV-2) is a rapidly spreading disease with a high mortality. In this research, the interactions between specific flavonols and the 2019-nCoV receptor binding domain (RBD), transmembrane protease, serine 2 (TMPRSS2), and cathepsins (CatB and CatL) were analyzed. According to the relative binding capacity index (RBCI) calculated based on the free energy of binding and calculated inhibition constants, it was determined that robinin (ROB) and gossypetin (GOS) were the most effective flavonols on all targets. While the binding free energy of ROB with the spike glycoprotein RBD, TMPRSS2, CatB, and CatL were -5.02, -7.57, -10.10, and -6.11 …

Cannabinoids For Sars-Cov-2 And Is There Evidence Of Their Therapeutic Efficacy?, Ahmet Onay, Abdulselam Ertaş, Veysel Süzerer, İsmai̇l Yener, Mustafa Abdullah Yilmaz, Emi̇ne Ayaz Ti̇lkat, Remzi̇ Eki̇nci̇, Nesri̇n Bozhan, Sevgi̇ İrtegün

Turkish Journal of Biology

To combat the coronaviruses and their novel variants, therapeutic drugs and the development of vaccines that are to be effective throughout human life are urgently needed. The endocannabinoid system (ECS) acts as a modulator in the activation of the microcirculation, immune system, and autonomic nervous system, along with controlling pharmacological functions such as emotional responses, homeostasis, motor functions, cognition, and motivation. The ECS contains endogenous cannabinoids, cannabinoid receptor (CBRs), and enzymes that regulate their biosynthesis, transport, and degradation. Moreover, phytocannabinoids and synthetic cannabinoids that mimic the action of endocannabinoids also play an essential role in the modulation of the ECS. …

Predatory Microtransaction Regulations: An International Comparison, Matt Hardy

South Carolina Journal of International Law and Business

No abstract provided.

Bangladesh-Bhutan Pta: Less Is More?, Md. Rizwanul Islam

South Carolina Journal of International Law and Business

While in the General Agreement on Tariffs and Trade (GATT) years, generally developed economies pursued preferential trade agreements (PTAs), and the states of the global South were also pursuing PTAs between and among each other. The recently concluded Bangladesh-Bhutan Preferential Trade Agreement (BBPTA) is an addition to this list. This article argues that the seemingly narrow scope of the BBPTA is somewhat deceptive. This is so because it covers products which are actually traded between the parties, and they create a substantial margin of preference. Thus, though the relatively liberal and simple rules of origin of the BBPTA is a …

Effects Of Harvest Regulations And Post-Release Hooking Mortality On Walleye Populations In South Dakota, Cade Lyon

Electronic Theses and Dissertations

Harvest regulations are commonly implemented to manipulate fisheries stocks. By regulating the size and number of fish that are harvested by anglers, managers are able to meet the goals and needs of regions. However, these management actions come with the potential for negative consequences. Overexploitation due to less restrictive harvest regulations can cause collapses in fisheries populations. In addition, indirect consequences such as hooking mortality brought on by length-based regulations can also be detrimental to populations. In this study, I investigated the effects of various harvest regulations on Walleye populations in three western South Dakota irrigation reservoirs: Angostura, Belle Fourche, …

Military Combat Veterans, Sentencing Reform, And Problem-Solving Courts, Andrea Sivanich

Theses and Dissertations

Military veterans involved with the criminal justice system may have unique behavioral health and physical needs, including post-traumatic stress disorder (PTSD) or traumatic brain injury (TBI), and could benefit from sentence mitigation that emphasizes rehabilitation. This research is related to sentencing reform and how it may support problem-solving court sentencing, as a subset of community-based treatment options within the criminal justice system. This research is important in that it attempts to determine whether the law distinguishes veteran offenders, as a specific population, from other offenders with treatment needs. To do that, this dissertation examines the role of legal texts in …

Legal Marijuana Disperser Owners' Lived Experiences About Accessing Banking Services, Jonathan Travis James

Walden Dissertations and Doctoral Studies

Marijuana reform has created a question of the potential market size of the legal marijuana industry on a local, state, or national level. The problem is that having no banking services has forced legal marijuana dispensaries to be cash-only businesses and created an increased risk of theft. The lack of normal banking services has also affected the ability to manage money earned from operations. This hermeneutic phenomenological study was grounded by the conceptual framework of the motivations of humans and humans' need to feel safe. The participants of this study were owners and operators in the legal marijuana industry of …