Digital Commons Network^™

Computational Modeling Of Climate Attributes And Condition Deterioration Of Concrete Highway Pavements, Salma Sultana

Electronic Theses and Dissertations

An efficient and safe road network secures the nation’s economy and prosperity by providing public mobility and freight transport. Maintenance and rehabilitation of the road network cost billions of dollars annually. Road and highway infrastructures performance in any country is impacted by load repetitions and it is further compromised by climate attributes and extreme weather events. Damages to roads and bridges are among the infrastructure failures that have occurred during these extreme events. If maintenance and rehabilitation are not done promptly, the damages to the road caused by heavy traffic and extreme climate may lead to life-threatening conditions for road …

The Expansion Of Shrimp Farms In The Gulf Of California And Potential For Restoration To Support Migratory Waterbirds, Miles Scheuering

Undergraduate Theses, Professional Papers, and Capstone Artifacts

Wintering and stopover areas provide crucial habitat for migratory birds yet are often understudied. The estuaries of Sonora and Sinaloa on the Gulf of California in Mexico provide critical wintering and stopover sites for migratory waterbirds in the Pacific Flyway. Shrimp farms are the greatest threat to these areas and their full impact is not well understood but they provide poor habitat for waterbirds. A significant portion of existing farms may be abandoned based on a disparity between active area reported by the Sonora and Sinaloa state commissions and observed area based on remote sensing. Abandoned farms represent potential area …

Scholarly Communication Competencies Self-Assessment, Nicole Webber, Jane Monson, Jennifer Mayer

University Libraries Publications

This self-assessment instrument is intended to: •understand librarian competencies and experiences regarding core areas of scholarly communications in order to improve research support services; assist with planning departmental and individual liaison goals related to research and scholarly communication support; help inform scholarly communication professional development for the department; and create a collaborative, non-punitive, and effective assessment process of research support.

Japanese Anime Fandoms In The Uae: An Exploratory Study On Media Accessibility, Habits And Cultural Perceptions, Urwa Mohammed Tariq, Sarah Laura Nesti Willard

CoHSS Faculty Work

The satellite TV revolution in the United Arab Emirates (UAE) in the early 1990s precipitated the proliferation of foreign media broadcasts. Japanese anime dubbed into Arabic became the most-watched content in Emirati households, a trend that continues to date because the Japanese entertainment and digital media industry offers youngsters easy access to and diverse options for anime. This paper provides an overview and analysis of the growing popularity of anime fandoms in the UAE to ascertain the level of commitment, involvement and the moral perceptions of Emirati fans vis-à-vis Japanese pop culture. A focus group discussion was conducted in a …

Comparison Of Methods Used In Predicting Irrigation Performance Indicators, Si̇nan Kartal, Firat Arslan

Turkish Journal of Agriculture and Forestry

Decreasing availability of water and increasing consumption of it in recent years shows water management plans increase its value. Depending on water consumption in the current and previous years, it is important to predict water consumption in the coming years and make plans accordingly. Evaluation of the performance of water use in agriculture, identifying water resources that are most intensively used and prediction of the potential performance in the coming years have become increasingly important. Irrigation water management is of crucial importance for sustainable food security and needs to plan for saving water due to global warming and climate change …

In-Vivo Wound Healing Activity Of A Novel Composite Sponge Loaded With Mucilage And Lipoidal Matter Of Hibiscus Species, Dalia Attia, Riham Bakr, Reham Amer, Mai Abdelhafez, Asmaa Al-Mokaddem, Abd El-Nasser El-Gendy, Ahlam El-Fishawy, Marwa Fayed, Sameh Gad

Pharmacy

Many researches have been undergone to hasten the natural wound healing process. In this study, several Hibiscus species (leaves) were extracted with petroleum ether, methanol, and their mucilage was separated. All the tested species extracts were assessed for their viability percentage using the water-soluble tetrazolium. H.syriacus was the plant of choice to be incorporated in a new drug delivery system and evaluated for its wound healing activity. H.syriacus petroleum ether extract (PEE) showed a high percentage of palmitic and oleic acids while its mucilage demonstrated high glucosamine and galacturonic acid. It was selected to be formulated and pharmaceutically evaluated into …

Chaetocin Enhances Callus Induction By Decreasing The Expression Of Major Leaf Polarity Genes In Nicotiana Tabacum, Ayyub Ebrahimi, Nagi̇han Özsoy, Saadet Deni̇z Gürle, Baki̇ Yaman, Şule Ari

Turkish Journal of Botany

Using chemicals known as inhibitors of chromatin remodeling enzymes is a useful approach in understanding the regulation machinery that contributes to the maintenance of or conversion to a pluri- and totipotent states of the cells in multicellular organisms. They can serve as tools to reveal the molecular and cellular mechanisms required for reprogramming. A deeper understanding of reprogramming pathways that drive the cell into a dedifferentiated state might help us enhance plant micropropagation and green biotechnology applications. Chaetocin is one of the histone methyltransferase inhibitors known as key drivers in several cellular processes. It was shown that chaetocin enhanced the …

Auxin-Induced Degradation Of Dream Proteins, Lin-9 And Lin-54, In Caenorhabditis Elegans, Karli E. Chosa

Dissertations, Master's Theses and Master's Reports

The Dp, Retinoblastoma, E2F, And MuvB (DREAM) complex mediates transcriptional repression and is highly conserved throughout a number of species, including vertebrates, Drosophila melanogaster, and Caenorhabditis elegans. Differing from mammalian DREAM, C.elegans DRM, appears to act solely in a repressive role, with the MuvB subcomplex (LIN-9, LIN-37, LIN-52, LIN-53, and LIN-54) playing a key role in the repression of genes. In this study, we use the auxin-inducible degron (AID) system, an effective, fast-acting, tool used in the degradation of degron-tagged proteins to individually deplete two key proteins of the MuvB subcomplex, LIN-9 and LIN-54, in C. elegans. The …

Economic Sustainability Analysis Of Natural Leather Industry, And Its Alternative Advancements, Yogesh Kumar Satish Kumar

Dissertations, Master's Theses and Master's Reports

Leather is one of the commonly worn fashion attires and accessories in the United States. But, despite the prevalence of leather fashion in the United States, the annual revenue of the leather industry has been decreasing steadily over the years. The purpose of this report is to investigate and discuss the probable reasons for the steady decline in the revenue. The U.S. government, after investigating the negative impact of the conventional leather manufacturing process, passed some environmental guidelines and regulations over the years. We will also discuss how these environmental regulations have been affecting the natural leather industry and also …

Multi-Level Analysis Of Atomic Layer Deposition Barrier Coatings On Additively Manufactured Plastics For High Vacuum Applications, Nupur Bihari

Dissertations, Master's Theses and Master's Reports

While hardware innovations in micro/nano electronics and photonics are heavily patented, the rise of the open-source movement has significantly shifted focus to the importance of obtaining low-cost, functional and easily modifiable research equipment. This thesis provides a foundation of open source development of equipment to aid in the micro/nano electronics and photonics fields.

First, the massive acceptance of the open source Arduino microcontroller has aided in the development of control systems with a wide variety of uses. Here it is used for the development of an open-source dual axis gimbal system. This system is used to characterize optoelectronic properties of …

Comparative Study Of Biocides And Nanoparticles On Bacterial Microorganisms, Rehab Alhajjar

Dissertations, Master's Theses and Master's Reports

The increase in antimicrobial-resistant bacteria has posed challenges to treating resistant diseases. Antimicrobials such as nanoparticles (NPs) and biocides are commonly used to control microbial growth in household and industrial settings. Several studies have shown that bacteria that become resistant to biocides can also resist antibiotics. There are fewer reports of resistance to nanoparticles. Our study goals were to compare the environmental effects of biocides and nanoparticles by investigating their impacts on stream microbial community structure, the mechanism of bacterial resistance, and their interactions with natural organic matter (NOM). Our results showed that biocides dramatically altered microbial community composition and …

Multi-Dimensional Modeling For Environmental Impact Assessment At Intersections Of The Food-Energy-Water Nexus, Jessica Daignault

Dissertations, Master's Theses and Master's Reports

This dissertation uses multi-dimensional modeling for environmental impact assessment at intersections of the Food-Energy-Water (FEW) Nexus, including life cycle assessment (LCA) modeling for quantification of environmental impacts due to household FEW consumption, a linear regression framework for quantification of water-use impacts of marginal electricity generation, and a multi-objective optimization model to assess monetization of water withdrawals for electricity generation and impacts to water stress due to electricity dispatch schemes. Chapter 2 of this dissertation summarizes the development of an LCA model that quantifies the direct and indirect environmental impacts of household FEW consumption. The model is executed through a novel …

The Effect Of Nutrition On Longevity And Fertility In Diverse Drosophila: A Tor-Mediated Process, Tessa E. Steenwinkel

Dissertations, Master's Theses and Master's Reports

Nutrition and growth are strongly linked, but not much is known about how nutrition leads to growth. To understand the connection between nutrition through diet, growth and/or proliferation, we need to study the phenotypes resulting from the activation and inhibition of central metabolic pathways. Here I use the model organism Drosophila melanogaster (D. mel.) and three non-model Drosophila species with different dietary needs, Drosophila guttifera (D. gut.), Drosophila deflecta (D. def.), and Drosophila tripunctata (D. tri.), to study the effects of dietary amino acid availability in these diverse flies on fecundity and …

Creativity As A Reflective Learning Exercise: Informing Strategic Marketing Decisions Through Digital Storytelling, Mario V. Gonzalez Fuentes, Kim R. Robertson, J. Charlene Davis

School of Business Faculty Research

As educators we strive to facilitate knowledge and ways of learning that serve students throughout their lives, but we also recognize their sometimes short retention span. The innovation we present in this article consists of the use of digital storytelling as a conduit for students to construct a narrative of their experience in a marketing simulation throughout the semester. We explain the innovation’s implementation as well as the results observed throughout the years in the digital stories developed by students. Finally, we discuss further applications of this innovation in other courses and future research avenues.

The Role Of Acetylcholine In Attention And Lapses In Attention In Rats Using The Mode And Deviation From Mode Of Reaction Time Latency, Scott Lee Mitchell

Electronic Theses and Dissertations

Attention Deficit-Hyperactivity Disorder (ADHD) is currently the neurodevelopmental disorder most commonly diagnosed in children in the United States, and one of the defining characteristics of ADHD is inattention. Inattention is marked by increased lapses in attention, and when assessed clinically, it has been highly correlated with reaction-time variability (RTV). Evidence from the human/clinical literature has shown an inherently higher RTV to be the primary quantitative indicator of an ADHD diagnosis. Reaction-time distributions are characterized by an asymmetrical rightward skew, and because of the prevalence of this presentation, it has been theorized that the distribution peak and skew represent separate phenomena, …

The House Of Love And The Mental Hospital: Zones Of Care And Recovery In South India, Murphy Halliburton

Publications and Research

The Movement for Global Mental Health has defined the person suffering psychopathology in low-income countries as an abused and suffering subject in need of saving by biomedical psychiatry. Based on fieldwork in Kerala, South India, carried out at psychiatric clinics and a psychosocial rehabilitation centre, this paper examines patients’ experiences of illness, the degree and quality of family support, and attributions made to the role of ‘sneham’, or love, in recovery. The role of love and family involvement may help explain the provocative finding by WHO epidemiological studies that ‘developing’ countries – and India in particular – showed better rates …

Rotavirus A Genome Segments Show Distinct Segregation And Codon Usage Patterns, Irene Hoxie, John J. Dennehy

Publications and Research

Reassortment of the Rotavirus A (RVA) 11-segment dsRNA genome may generate new genome constellations that allow RVA to expand its host range or evade immune responses. Reassortment may also produce phylogenetic incongruities and weakly linked evolutionary histories across the 11 segments, obscuring reassortment-specific epistasis and changes in substitution rates. To determine the co-segregation patterns of RVA segments, we generated time-scaled phylogenetic trees for each of the 11 segments of 789 complete RVA genomes isolated from mammalian hosts and compared the segments’ geodesic distances. We found that segments 4 (VP4) and 9 (VP7) occupied significantly different tree spaces from each other …

La Traducción De Textos Humanísticos En Los Siglos De Oro, Adrian Izquierdo

Publications and Research

No abstract provided.

การตรวจหาดีเอ็นเอเพศชายจากตัวอย่างน้ำซับช่องคลอด โดยเทคนิคลูปมีดิเอเตดไอโซเทอร์มอลแอมพลิฟิเคชัน, สุนิตา ชุณห์กุล

Chulalongkorn University Theses and Dissertations (Chula ETD)

คดีข่มขืนกระทำชำเราเป็นคดีอาญาที่เกิดขึ้นเป็นอันดับต้น ๆ ในประเทศไทย การตรวจสอบหลักฐานในตัวอย่างสิ่งส่งตรวจคดีข่มขืนกระทำชำเราทางนิติวิทยาศาสตร์ต้องผ่านการตรวจสอบทางห้องปฏิบัติการ โดยในปัจจุบันใช้วิธีการตรวจคัดกรอง (screening test) ด้วยเอนไซม์แอซิดฟอสฟาเตส และการตรวจสอบยืนยัน (confirmatory test) ด้วยการส่องกล้องจุลทรรศน์หาอสุจิ ซึ่งทั้ง 2 วิธีมีความจำเพาะและความไวสูง แต่มีข้อจำกัดและโอกาสในการเกิดผลบวกหรือผลลบเทียมได้ เพื่อเพิ่มความสามารถและลดข้อผิดพลาดจากการตรวจ การศึกษานี้มีวัตถุประสงค์เพื่อตรวจหาดีเอ็นเอเพศชายจากตัวอย่างน้ำซับช่อคลอดโดยเทคนิคลูปมีดิเอเตดไอโซเทอร์มอลแอมพลิฟิเคชัน (LAMP) ที่มีความไวสูงและสามารถทำซ้ำแล้วให้ผลตรงกัน โดยออกแบบไพรเมอร์ที่จำเพาะกับยีนอเมโลจีนินวายเพื่อใช้ในการตรวจหาดีเอ็นเอเพศชายจากตัวอย่างน้ำซับช่องคลอดด้วยเทคนิค LAMP ผลการศึกษาพบว่าเทคนิค LAMP มีความไวสูงในการตรวจหาดีเอ็นเอเพศชายปริมาณตั้งแต่ 0.1 นาโนกรัมขึ้นไป ความจำเพาะในการตรวจสอบต่อดีเอ็นเอเป้าหมายสูงโดยแสดงผลบวกในกรณีที่ตรวจพบดีเอ็นเอมนุษย์เพศชายเท่านั้น ซึ่งไม่มีการแสดงผลในดีเอ็นเอมนุษย์เพศหญิง และดีเอ็นเอสัตว์ (หนูเม้าส์ หนูแรท และหมู) นอกจากนั้น ผลจากการตรวจสอตัวอย่างในคดีข่มขืนที่เกิดขึ้นจริงในประเทศไทยจำนวน 92 ตัวอย่าง แสดงให้เห็นว่าเทคนิค LAMP มีความแม่นยำในการตรวจสอบสูงถึงร้อยละ 96.7 ซึ่งแม่นยำกว่าการตรวจสอบด้วยชุดน้ำยาแอซิดฟอสฟาเตสและการตรวจหาอสุจิด้วยกล้องจุลทรรศน์ที่มีความถูกต้องในการตรวจสอบร้อยละ 57.6 และ 79.3 ตามลำดับ และสามารถใช้สารสีฟีนอลเรดในการตรวจสอบการเกิดปฏิกิริยาของเทคนิค LAMP จากผลการศึกษาแสดงให้เห็นว่าเทคนิค LAMP สามารถใช้เป็นวิธีทางเลือกในการตรวจสอบเบื้องต้นสำหรับคดีข่มขืนได้

Doxepin Accelerates The Healing Process Of Burn Wounds In Mice, Elham Saberzadeh, Mohsen Zabihi, Ehsan Motaghi, Fatemeh Shishehbor

The Thai Journal of Pharmaceutical Sciences

Wound healing following a skin burn is still a concern due to poor effectiveness and the side effects of the available topical and systemic drugs. Doxepin hydrochloride is an approved antidepressant drug (Application No.: 022036) which is effective for the treatment of moderate pruritus in patients with eczema and atopic dermatitis. The current study has evaluated the effect of topical and systemic doxepin to improve the histopathologic process of second-degree burn wound in mice. The mice were divided into six groups (n = 6), including topical normal saline group, topical glycerin group, positive control group (topical phenytoin), topical doxepin 5% …

Environmental Crimes And Green Victimization, Averi R. Fegadel

Faculty Publications

The field of criminology continues to give little attention to the behaviors and crimes that adversely impact the environment although decades of research has highlighted these crimes result in greater social harms, losses, and deaths compared to traditional street crimes. Moreover, these crimes are met with little consequences despite several laws and regulations charged with protecting the environment and public welfare. As a result, residents of minority and poor communities are faced with social, racial, and economic inequalities. This draws attention to the green victimization of marginalized groups and underrepresented populations worldwide. In the United States, these groups include Native …

The Application Of Systems Science In Nutrition-Related Behaviors And Outcomes Implementation Research: A Scoping Review, Ayron E. Walker, Rachel A. Wattick, Melissa D. Olfert

Faculty & Staff Scholarship

Use of systems science can improve the dissemination and implementation (D&I) process. However, little is known about use of systems science in nutrition D&I research. The purpose of this article is to synthesize the ways in which systems science methodology is applied in nutrition D&I research. Scoping review methodology involved searching 6 academic databases for full-text, peer-reviewed, English articles published between 1970 and 2020 that employed systems science within nutrition D&I research. Data extraction included intervention type, population, study aim, methods, theoretical approach, outcomes, and results. Descriptive statistics and qualitative thematic analysis followed. Thirty-four retained articles qualitatively identified benefits (successful …

Synthesis And Evaluation Of Hepatoprotective Effects Of A Tetrahydrocurcumin-Diglutaric Acid Prodrug, Nattapong Jongjitphisut

Chulalongkorn University Theses and Dissertations (Chula ETD)

Alcoholic liver disease (ALD) is a significant public health problem worldwide. Numerous natural molecules, including curcumin, have been extensively studied as potential treatment agents for ALD. Tetrahydrocurcumin (THC), the reductive metabolite of curcumin, was previously reported to exert the potent antioxidant activity against chemical-induced oxidative stress suggesting the potential of THC to be used as a protective agent for ALD. However, THC has poor water solubility limiting its pharmacological activity. In the present study, tetrahydrocurcumin-diglutaric acid (TDG) was synthesized. The solubility of TDG at pH 6.8 was higher than THC approximately 20 times with a logP value of 3.03. TDG …

Synergistic Effect Of Metal Ion Reduction And Nano-Titania Photocatalysis For Cyanate Degradation And Its Life Cycle Assessment, Atima Dubsok

Chulalongkorn University Theses and Dissertations (Chula ETD)

Environmental consequences of mining are becoming increasingly complex, especially the utilization of toxic chemicals in the mineral process. Specifically, in the gold mining operations, the various species of remaining cyanide in the tailings stream are potentially toxic and hazardous to human health and the environment. Although many studies have spotlighted on cyanide toxicity and their environmental health impacts, the focus on possible treatment techniques that can be applied to treat other toxic species is however limited. Cyanate, for instance, is an intermediate product from the destruction of cyanide in wastewater and known as a neurotoxic substance. Altogether, the remaining of …

การพัฒนาหนังสือการ์ตูนเออาร์ด้วยเทคนิค Pwim เพื่อพัฒนาความสามารถในการอ่านสำหรับนักเรียนประถมศึกษาตอนต้น, พีริยา หาญบำรุงธรรม

Chulalongkorn University Theses and Dissertations (Chula ETD)

การวิจัยครั้งนี้มีวัตถุประสงค์เพื่อ 1) พัฒนาหนังสือการ์ตูนเออาร์ด้วยเทคนิค PWIM 2) ศึกษาผลการใช้หนังสือการ์ตูนเออาร์ด้วยเทคนิค PWIM กลุ่มตัวอย่างที่ใช้ในการศึกษาผลการใช้หนังสือการ์ตูนเออาร์ด้วยเทคนิค PWIM คือนักเรียนชั้นประถมศึกษาปีที่ 2 แบ่งเป็นกลุ่มทดลองและกลุ่มควบคุมอย่างละ 30 คน เครื่องมือที่ใช้ในการวิจัยได้แก่ แบบทดสอบก่อนเรียนและแบบทดสอบหลังเรียน แบบบันทึกการอ่านออกเสียงและการอ่านรู้เรื่อง แผนการจัดการเรียนรู้ หนังสือการ์ตูนเออาร์ด้วยเทคนิค PWIM วิเคราะห์ข้อมูลด้วยร้อยละ ค่าเฉลี่ย และส่วนเบี่ยงเบนมาตรฐาน และT-test ผลการวิจัยพบว่า หนังสือการ์ตูนเออาร์มีขั้นตอนการพัฒนาหนังสือการ์ตูนเออาร์ฯ ดังนี้ 1) การศึกษาเอกสารและวิเคราะห์ข้อมูล 2) การออกแบบ 3) การตรวจสอบเนื้อหา 4) การพัฒนาหนังสือ 5) การตรวจสอบสื่อหนังสือ 6) การนำไปใช้ 7) การประเมินผล องค์ประกอบของหนังสือการ์ตูนเออาร์ฯ ประกอบด้วย 1) การ์ตูนแอนิเมชั่น 2 มิติ และการ์ตูนประกอบเรื่อง 2) ตัวชี้วัดภาษาไทย 3) เนื้อเรื่อง 4) ตัวละคร 5) ความเป็นจริงเสริม ขั้นตอนการใช้มี 4 ขั้นตอนดังนี้ 1) การดูรูปภาพและระบุคำศัพท์ 2) การอ่านออกเสียงเพื่อเชื่อมโยงคำและรูป 3) การจัดกลุ่มคำหรือการคิดแบบอุปนัย 4) การนำไปใช้ และผลการวิเคราะห์ความสามารถในการอ่านก่อนเรียนและหลังเรียนของกลุ่มทดลองเก่ง กลาง อ่อนพบว่ากลุ่มทดลองทุกกลุ่มมีความสามารถในการอ่านหลังเรียนสูงกว่าก่อนเรียนอย่างมีนัยสำคัญทางสถิติที่ระดับ .05 นอกจากนี้ผลจากการวิเคราะห์ความสามารถในการอ่านหลังเรียนของกลุ่มทดลองและกลุ่มควบคุมพบว่ากลุ่มทดลองกลุ่มเก่ง กลาง อ่อนมีความสามารถในการอ่านหลังเรียนสูงกว่ากลุ่มควบคุมกลุ่มเก่ง กลาง อ่อนอย่างมีนัยสำคัญทางสถิติที่ระดับ .05

Changes In The Philippine Coastal Environment, Karl H. Szekielda, Ma. Aileen Leah G. Guzman

Environmental Science Faculty Publications

Global warming is progressing at a faster speed than has been estimated earlier in climate forecasting, and the ocean responds rather quickly to global temperature increase. This study uses remotely sensed data that were accessed from the System for Multidisciplinary Research and Applications (NASA Giovanni) to study environmental change in the Philippines’ coast. Monthly averaged sea surface temperature series from around the Philippines indicate that the Philippines follow the global trend in ocean temperature increase and show the increase of about 0.50C within two decades. Despite the high variability in temperature, the linear regressions displayed for all seasons show an …

A Deep Learning Model For Predicting Long Non-Coding Rna And Messenger Rna With Model Interpretation, Rattaphon Lin

Chulalongkorn University Theses and Dissertations (Chula ETD)

Long non-coding RNAs (lncRNAs) play important roles in many biological processes and are found to be associated with several diseases. The development of next-generation sequencing technologies has discovered numerous unannotated transcripts. However, classifying these unannotated transcripts by using biological experiments is very time-consuming and expensive. Thus, a computational approach is considered as an alternative solution which is faster and cheaper. Many existing lncRNA identification tools are available, these tools lack an explanation of which features contributed to their prediction results. Here, we present Xlnc1DCNN, a tool for distinguishing long non-coding RNAs (lncRNAs) from protein-coding transcripts (PCTs) together with a prediction …

Arsenic Removal From The Contaminated Soil By Bio-Based Washing Agent In A Combined Mechanical Agitation And Ultrasonication Process, Polwatte Arachchillaya Buddhika Prabath Abeyrathne

Chulalongkorn University Theses and Dissertations (Chula ETD)

A significant amount of arsenic (As) pollution has been found globally, with several health consequences. Soil washing is a cost-effective mix of chemical and physical procedures that have been used to remove heavy metals from polluted soil. This study investigated the possibility of using a lipopeptide biosurfactant from Bacillus subtilis GY19 as a washing agent to remove As from contaminated soil. To improve the effectiveness of biosurfactants, sodium carbonate and ethylenediaminetetraacetic acid (EDTA) were employed as builders to minimize the influence of exchangeable cations in the soil. The agricultural soil utilized in the study was spiked with As at an …

Development Of Fenofibrate/Cyclodextrin Complex Loaded Eudragit Nanoparticles For Ocular Delivery, Soe Yadanar Khin

Chulalongkorn University Theses and Dissertations (Chula ETD)

The purpose of this study was to develop Eudragit® -nanoparticles (NPs) eye drop formulations containing fenofibrate (FE) for diabetic retinopathy and age-related macular degeneration. Due to the limited aqueous solubility of FE, it may hamper the ocular bioavailability and results in low efficiency to treat such diseases. Hence, the increased solubility of FE was determined by complexation with cyclodextrins (CDs) and CD derivatives The solubility determination was evaluated by phase-solubility technique with heating method. Among CD tested, randomly methylated-b-CD (RMbCD) exhibited the best solubilizer with the highest complexation efficiency for FE. Moreover, the water-soluble polymer i.e., Soluplus® (SOL), poloxomer 407 …

Development Of Bio-Based Nanocomposites For Biosensor And Indicator Applications In Smart Food Packaging, Abdus Sobhan

Electronic Theses and Dissertations

Smart food packaging based on biosensors has been attracting more and more interest to the industrial community because of the concerns of food quality and safety. A food packaging with biosensor has a scope to enable real-time monitoring of microbial breakdown products of packaged foods. Furthermore, one of the biggest challenges in implementing biosensor for smart packaging materials is the development of bio-sensing active materials that can leverage their electrical, thermal, biodegradable and other functional properties. In this regard, nanocellulose-based activated carbon (NAC) nanocomposite was developed using the activated carbon and nanocellulose gel using the casting method with their different …