Digital Commons Network^™

Effect Of Mutation And Vaccination On Spread, Severity, And Mortality Of Covid-19 Disease, Dr Hossam Zawbaa, Hasnaa Osama, Ahmed El‐Gendy, Haitham Saeed, Hadeer S. Harb, Yasmin M. Madney, Mona Abdelrahman, Marwa Mohsen, Ahmed M.A. Ali, Mina Nicola, Marwa O. Elgendy, Ihab A. Ibrahim, Mohamed E.A. Abdelrahim

Articles

Coronavirus disease 2019 (COVID-19) has had different waves within the same country. The spread rate and severity showed different properties within the COVID-19 different waves. The present work aims to compare the spread and the severity of the different waves using the available data of confirmed COVID-19 cases and death cases. Real-data sets collected from the Johns Hopkins University Center for Systems Science were used to perform a comparative study between COVID-19 different waves in 12 countries with the highest total performed tests for severe acute respiratory syndrome coronavirus 2 detection in the world (Italy, Brazil, Japan, Germany, Spain, India, …

Socioeconomic Challenges Of California Strawberry Production And Disease Resistant Cultivars, Julie Guthman, Estelí Jiménez-Soto

School of Geosciences Faculty and Staff Publications

Strawberries are the 4th highest grossing crop in California and supply 90% of US strawberries. But the industry's long reliance on the use of chemical fumigants to control soil disease, nematodes and weeds is being threatened by increased regulation of these fumigants, leading to urgent efforts to develop and test non-chemical alternatives to fumigation, such as disease resistant cultivars. Many of these technologies are promising ecologically, but making them economically viable for growers is more challenging, especially in light of the socioeconomic context of strawberry production in California that has created a state of lock-in for a sustainability transition. This …

Gender In Eastern Mesolithic Europe As Seen Through Grave Clusters, Danielle Norris

Student Scholarship

No abstract provided.

State Changes: Insights From The U.S. Long Term Ecological Research Network, Julie C. Zinnert, Jesse B. Nippert, Jennifer A. Rudgers, Steven C. Pennings, Grizelle González, Merryl Alber, Sara G. Baer, John M. Blair, Adrian Burd, Scott L. Collins, Christopher Craft, Daniela Di Iorio, Walter K. Dodds, Peter M. Groffman, Ellen Herbert, Christine Hladik, Fan Li, Marcy E. Litvak, Seth Newsome, John O’Donnell, William T. Pockman, John Schalles, Donald R. Young

Advanced Science Research Center

Understanding the complex and unpredictable ways ecosystems are changing and predicting the state of ecosystems and the services they will provide in the future requires coordinated, long-term research. This paper is a product of a U.S. National Science Foundation funded Long Term Ecological Research (LTER) network synthesis effort that addressed anticipated changes in future populations and communities. Each LTER site described what their site would look like in 50 or 100 yr based on long-term patterns and responses to global change drivers in each ecosystem. Common themes emerged and predictions were grouped into state change, connectivity, resilience, time lags, and …

Ifn-Β Acts On Monocytes To Ameliorate Cns Autoimmunity By Inhibiting Proinflammatory Cross-Talk Between Monocytes And Th Cells., Javad Rasouli, Giacomo Casella, Larissa Ishikawa, Rodolfo Thome, Alexandra Boehm, Adam Ertel, Carolina R Melo-Silva, Elisabeth R. Mari, Patrizia Porazzi, Weifeng Zhang, Dan Xiao, Luis J. Sigal, Paolo Fortina, Guang-Xian Zhang, A M Rostami, Bogoljub Ciric

Department of Neurology Faculty Papers

IFN-β has been the treatment for multiple sclerosis (MS) for almost three decades, but understanding the mechanisms underlying its beneficial effects remains incomplete. We have shown that MS patients have increased numbers of GM-CSF+ Th cells in circulation, and that IFN-β therapy reduces their numbers. GM-CSF expression by myelin-specific Th cells is essential for the development of experimental autoimmune encephalomyelitis (EAE), an animal model of MS. These findings suggested that IFN-β therapy may function via suppression of GM-CSF production by Th cells. In the current study, we elucidated a feedback loop between monocytes and Th cells that amplifies autoimmune neuroinflammation, …

Collagen Structure-Function Mapping Informs Applications For Regenerative Medicine., James D San Antonio, Olena Jacenko, Andrzej Fertala, Joseph P R O Orgel

Department of Orthopaedic Surgery Faculty Papers

Type I collagen, the predominant protein of vertebrates, assembles into fibrils that orchestrate the form and function of bone, tendon, skin, and other tissues. Collagen plays roles in hemostasis, wound healing, angiogenesis, and biomineralization, and its dysfunction contributes to fibrosis, atherosclerosis, cancer metastasis, and brittle bone disease. To elucidate the type I collagen structure-function relationship, we constructed a type I collagen fibril interactome, including its functional sites and disease-associated mutations. When projected onto an X-ray diffraction model of the native collagen microfibril, data revealed a matrix interaction domain that assumes structural roles including collagen assembly, crosslinking, proteoglycan (PG) binding, and …

Confronting Colonial Violence: Pueblo Women Using Indigenous History For Community Activism And Healing, Sierra Mondragón , '21

Senior Theses, Projects, and Awards

Combining a critical dive into the archives of Indigenous history, a survey of Indigenous historiography, and recorded interviews with Pueblo women-led organizations Tewa Women United and Three Sisters Collective, this research focuses on how contemporary Pueblo Indigenous women use Indigenous models of history to confront ongoing forms of colonial violence. The programming and activist efforts of both organizations are highlighted for their ability to confront historical issues of sexual and physical violence, family disruption and trauma, and forced sterilization. The connections made between Indigenous history and the narratives of TWU and 3SC reveal successful models for how Indigenous history can …

Distinct Cellular Profiles Of Hif1a And Vegf Mrna Localization In Microglia, Astrocytes And Neurons During A Period Of Vascular Maturation In The Auditory Brainstem Of Neonate Rats, Daphne Chang, Quetanya Brown, Grace Tsui, Ye He, Jia Liu, Lingyan Shi, Adrián Rodríguez-Contreras

Advanced Science Research Center

Defining the relationship between vascular development and the expression of hypoxia-inducible factors (Hifs) and vascular endothelial growth factor (Vegf) in the auditory brainstem is important to understand how tissue hypoxia caused by oxygen shortage contributes to sensory deficits in neonates. In this study, we used histology, molecular labeling, confocal microscopy and 3D image processing methods to test the hypothesis that significant maturation of the vascular bed in the medial nucleus of the trapezoid body (MNTB) occurs during the postnatal period that precedes hearing onset. Isolectin-B4 histochemistry experiments suggested that the MNTB vasculature becomes more elaborate between …

Service Speaks 2021, Service Speaks Committee, Depaul University

Service Speaks

Service Speaks is an annual conference that demonstrates the multitude of ways DePaul students work with community partners to advance social justice causes in Chicago communities. Each academic year, over 200 courses and programs send students into the community to lift up the assets of our community partners through community-based service learning (CbSL) and project-based classes, community internships and community-based research. These connections result in mutually beneficial outcomes for the community organization and provide transformational experiences for our students.

2021 Service Speaks Annual Conference Chapbook, 2021 Service Speaks Committee

Other Research and Reports

Service Speaks is an annual conference that demonstrates the multitude of ways DePaul students work with community partners to advance social justice causes in Chicago communities. Each academic year, over 200 courses and programs send students into the community to lift up the assets of our community partners through community-based service learning (CbSL) and project-based classes, community internships and community-based research. These connections result in mutually beneficial outcomes for the community organization and provide transformational experiences for our students.

The Wild Horses Of Tybee Island, B.J. Hollars

Sunday Short Reads

No abstract provided.

After Hours, Rebecca Turkewitz

Sunday Short Reads

No abstract provided.

Rango, Jarrett G. Ziemer

Sunday Short Reads

No abstract provided.

From Inner Segment To Outer Segment: Palmitoylation Of Photoreceptor Na+, K+-Atpase And The Importance Of Prcd In Photoreceptor Outer Segment Morphogenesis, Emily R. Sechrest

Graduate Theses, Dissertations, and Problem Reports (ETD)

Photoreceptors are specialized neuroepithelial cells which are optimized for efficient capture of light and initiation of visual transduction. These cells have several compartments which are very important for proper visual function and segregation of cellular processes, including the outer segment (OS), inner segment (IS), nucleus, and synapse. The IS houses all of the cellular organelles and biosynthetic molecular machinery the cell requires and is the site of protein synthesis. The light-sensing OS is a highly modified, primary cilium, which contains many stacks of double membranous discs which house proteins required for formation and maintenance of OS structure, as well as …

Observational Measurement Of Attachment In Toddlers With Disruptive Behavior Using The Strange Situation Procedure And Attachment Q-Set, Corey C. Lieneman

Graduate Theses, Dissertations, and Problem Reports (ETD)

Child-caregiver attachment is an important factor in healthy child development and is often targeted by early intervention programs. To assess the efficacy of these interventions, attachment must be accurately measured across the toddler years in populations referred for treatment of externalizing behavior problems. The Strange Situation Procedure (SSP; Ainsworth et al., 1978) and Attachment Q-Set (AQS; Waters, 1987) are empirically-validated measures of child-caregiver attachment, each with unique strengths and weaknesses. Previous research has reached mixed conclusions on relations between the observer-report AQS and SSP, depending on sample and study characteristics, and a review of the literature did not produce any …

In Vitro And In Vivo Toxicological Evaluation Of Emissions From The Fused Filament Fabrication Three-Dimensional Printing, Mariana T. Farcas

Graduate Theses, Dissertations, and Problem Reports (ETD)

Fused filament fabrication (FFF), a three-dimensional (3-D) printing process, is an emerging technology that has recently gained wide popularity among both consumers and manufacturers. As filament is heated to above its glass transition temperature in a 3-D printer, a portion may undergo thermal decompostion, which releases ultrafine particles (UFP) and volatile organic compounds (VOCs) with potential adverse respiratory health effects are released into the air. This study's central hypotheses is that emissions generated during 3-D printing are toxic and exposure to these emissions induces pulmonary and systemic adverse health effects. Considering that currently, limited understanding is available on the health …

Soil Response Of Helicopter Liming In The Monongahela National Forest, Jarrett Douglas Fowler

Graduate Theses, Dissertations, and Problem Reports (ETD)

Soils in the Monongahela National Forest (MNF) are acidic due to sandstone parent material, acid deposition, uptake of base cations by vegetation, and release of organic acids by organic matter (OM) decomposition. Increases in soil acidity have caused declines in forest health and changed species composition and nutrient status. Liming can neutralize soil acidity, but no large-scale liming projects have been done on acid forest soils in the USA. In anticipation of acquiring funding for a proposed liming project in the MNF, in 2007 and 2009 10 sites were selected to sample and analyze soils before lime was applied. In …

Level Of Adoption Of West Virginia Agriculture Teachers' Usage Of Internet-Based Educational Technology In The Classroom, Travis Daniel Veach

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to determine the level of adoption of West Virginia agricultural educators’ usage of internet-based educational technology for instruction. The population for this study included 103 educators during the 2020-2021 school year. The study yielded thirty-two responses from the population. Respondents indicated they use internet-based educational technology for their classroom instruction. Respondents indicated they use internet-based educational technology in a variety of different ways for instruction. Respondents adopted internet-based educational technology at varying degrees depending on the technology, some respondents being early adopters, and others later adopters.

Developing A Discipleship Program For Chinese Speaking People To Create A Core Team For The “Abiding Christ Net” Via Zoom Video Conference, Sung Sub Song

Doctor of Ministry Projects

Problem

The Seventh-day Adventist Office of Archives, Statistics, and Research (ASTR) data in December 2019 showed that among the 1.4 billion population in the Mainland China, there were 467,516 Adventist members, and the population per Adventist member ratio was about 3,000:1. Furthermore, there are about 50 million Chinese people living overseas. As a result, there is a great need to efficiently and effectively spread the Gospel to nearly 1.45 billion Chinese people around the world. In July 2020, the online Chinese discipleship network, ACN, was established to create a global Chinese discipleship network by connecting and utilizing Spirit-filled human resources, …

An Evangelism And Discipleship Pathway To Address The Cultural And Worldview Distance Between The Preston Seventh-Day Adventist Church And The White British Culture In Preston, Jeff Keith Couzins

Doctor of Ministry Projects

Problem.

The UK Preston Seventh-day Adventist Church in the North England Conference is a predominantly Black church situated in a White British city. The Church has seen a numerical increase of almost 25% since 2013, but only one person from this growth was from the majority culture population, a group who tend not to be attracted to traditional Adventist forms of evangelism. The hypothesis for this project, therefore, is that when the cultural and worldview distance between church members and individuals in society is reduced, it is easier for the Christian witness to then explain the Kingdom of God. Also, …

Property Law For The Ages, Lior Strahilevitz, Michael C. Pollack

Coase-Sandor Institute for Law & Economics Research Paper Series

Within the next forty years, the number of Americans over age sixty-five is projected to nearly double. This seismic demographic shift will necessitate a reckoning in several areas of law and policy, but property law is especially unprepared. Built primarily for young and middle-aged white men, the common law of property has been critiqued for decades for the ways in which it oppresses or simply leaves behind people based on their race, sex, Native heritage, and more. This Article contributes a new focus on property law’s treatment of people based on their advanced age. Burdened by higher relocation costs, more …

Options For Low-Cost Manufacturing And Safer Cell Therapies, Melis Keceli

Master's Theses

The proposed work aims to overcome the economical and feasibility-related limitations of the chimeric antigen receptor therapies by developing an artificial cell signaling pathway whose design transforms K562 cells into in vivo living vectors to synthesize therapeutic proteins upon engaging diseased cells in the treatment of ovarian cancer. There are various advantages of using K562 cells throughout this process. First, Food and Drug Administration approves the reinfusion of K562 cells into patients’ bodies. Second, K562 cells are more affordable than T lymphocytes, and finally, these cells can be easily manipulated with any desired genetic material and can keep the expression …

Effects Of Biofertilizer On Soil Nutrient Cycling And The Productivity Of Bioproduct Crops In Marginal Soils, Kieran B. Liseski

Graduate Theses, Dissertations, and Problem Reports (ETD)

Recently there has been increased interest in the use of marginal lands in order to grow bioproduct crops. Utilizing marginal lands to grow bioproduct crops such as Miscanthus x giganteus and Panicum virgatum could not only improve soil quality and minimize negative environmental impacts on the surrounding ecosystems but could also offer economic benefits to growers in rural areas. Because marginal soils tend to reduce crop yields compared to prime farmlands even when growing bioproduct crops, which tend to be more robust than traditional food crops, augmenting the soil with biofertilizers (i.e., the direct addition of viable microbial cells) could …

Insect Community Associated With Black Cherry (Prunus Serotina) In The Allegheny National Forest, Craig James Larcenaire

Graduate Theses, Dissertations, and Problem Reports (ETD)

Black cherry (Prunus serotina Ehrh.) is valuable species managed for its economic and ecologic benefits. This species grows best in the environment of the Allegheny Plateau region in northwestern Pennsylvania. Land managers on the Allegheny National Forest (ANF) have been managing black cherry for a variety of goals and purposes. Over the last few decades, the land managers have noticed a decline in the natural regeneration of black cherry in the forest. Because the black cherry flowers are self-incompatible and require animal pollinators to transfer the pollen from one tree to another one hypothesis for this decline could be …

Influence Of Anthropogenic Subsidies On Movements Of Common Ravens, Adam E. Duerr, Peter H. Bloom, Kerry Ross, Tricia A. Miller, Melissa A. Braham, Amy L. Fesnock, Todd E. Katzner

Human–Wildlife Interactions

Anthropogenic subsidies can benefit populations of generalist predators such as common ravens (ravens; Corvus corax), which in turn may depress populations of many types of species at lower-trophic levels, including desert tortoises (Gopherus agassizii) or greater sage-grouse (Centrocercus urophasianus). Management of subsidized ravens often has targeted local breeding populations that are presumed to affect species of concern and ignored “urban” populations of ravens. However, little is known about how ravens move, especially in response to the presence of anthropogenic subsidies. Therefore, subsidized ravens from distant populations that are not managed may influence local prey. To …

Demography, Morphometrics, And Stomach Contents Of Common Ravens Examined As A Result Of Controlled Take, Corinne M. Gibble, Kriss K. Neuman, Jessie Beck

Human–Wildlife Interactions

Common ravens (Corvus corax; ravens) are known nest predators that have the ability to negatively impact nesting birds, including imperiled species of seabirds and shorebirds. We conducted systematic necropsies of ravens that were lethally controlled in Monterey Bay, California, USA during 2013–2015, in or near western snowy plover (Charadrius nivosus nivosus) nesting areas, in an effort to better understand body condition, overall health, and diet of individual ravens. Raven predation of snowy plover nests has increased over the years in the Monterey Bay study area, and lethal removal of ravens has been employed to reduce predation. …

A Rapid Assessment Function To Estimate Common Raven Population Densities: Implications For Targeted Management, Brianne E. Brussee, Peter S. Coates, Shawn T. O'Neil, Seth J. Dettenmaier, Pat J. Jackson, Kristy B. Howe, David Delehanty

Human–Wildlife Interactions

Common raven (Corvus corax; raven) populations have increased over the past 5 decades within the western United States. Raven population increases have been largely attributed to growing resource subsidies from expansion of human enterprise. Concomitantly, managers are becoming increasingly concerned about elevated adverse effects on multiple sensitive prey species, damage to livestock and agriculture, and human safety. Managers could benefit from a rapid but reliable method to estimate raven densities across spatiotemporal scales to monitor raven populations more efficiently and inform targeted and adaptive management frameworks. However, obtaining estimates of raven density is data- and resource-intensive, which renders …

A Novel Technique To Improve Capture Success Of Common Ravens, Lindsey R. Perry, Terrah M. Owens, Zachary T. Slick, Jimmy D. Taylor, Jonathan B. Dinkins

Human–Wildlife Interactions

Traditional trapping techniques for common ravens (Corvus corax; raven) require significant effort, often produce low capture rates, and cannot be used in some situations. We designed a 3-m noose pole to secure ravens from nocturnal roost locations while using a strobe spotlight to temporarily disorient them. We collected measures of trapping efficiency and contrasted them with padded leghold traps also used in the study. We effectively implemented our noose pole method in July and August of 2018, 2019, and 2020 in the Baker and Cow Lakes sage-grouse (Centrocercus urophasianus) Priority Areas of Conservation in eastern Oregon, …

Noncompliance With Regulations On The Use Of Safety Helmets By Motorcyclists In Tamale, Ghana, Mohammed Wumbei

Walden Dissertations and Doctoral Studies

AbstractMotorcyclists’ nonadherence to safety helmet regulations results in an increased risk of accidents, often leading to traumatic injuries or death. This noncompliance is prevalent in the rural and peri-urban areas of the developing world, particularly in Tamale, Ghana. The purpose of this qualitative case study research was to apply the theoretical framework of rational choice theory in the examination of motorcyclists’ considerations in deciding whether to comply with government safety helmet regulations. Motorcyclists in Tamale were convenience sampled for observation and a subset recruited for interview. The study followed the qualitative case study approach by conducting observations and in-depth face-to-face …

The Other’S Humanity With Or Without The Other’S Religiosity, Retief Müller

University Faculty Publications and Creative Works

Taking Wentzel van Huyssteen’s work on early human uniqueness in relation to symbolic or religious awareness as a starting point, this article raises a question whether an implicit connection between humanity and the capacity for religiosity had anything to say about how one could evaluate the so-called other’s religion and their humanity. Does the recognition of the other’s full humanity demand an equal recognition of their religiosity, or are these separable? Rather than attempting to answer this hypothetically, the question is approached historically. The article touches on how the capacity to evaluate religion from the outside emerged in modernity and …