Digital Commons Network^™

A Practitioner's Guide: Using The Cognitive Performance Test To Increase Independent Living Skills For Individuals With Intellectual Disabilities, Alycia Peacock, Grace Spanos

Occupational Therapy Capstones

Problem: Individuals with intellectual disabilities (ID) have the desire to live as independently as possible (Gragoudas, 2014). There are a number of barriers that impact living independently including the ability to complete self-care tasks, money management, home management, and health management (Bond & Hurst, 2010). Other barriers reported for individuals with ID include relationships with caregivers, living alone, and vulnerability (Bond & Hurst, 2010). Research identifies that it is difficult to determine the amount of support needed to promote independence in individuals with ID (Francis & Reed, 2019). Occupational therapists (OTs) possess a unique skillset to assist clients with ID …

Empowering Grand-Families Through Occupation: An Occupational Therapy Intervention Program For Grandchildren And Custodial Grandparents, Macie Romsdal, Gabrielle Wavra

Occupational Therapy Capstones

The purpose of this scholarly project was to create a program for occupational therapists to use with custodial grandparents and their grandchildren. The number of grandparents becoming primary caregivers to grandchildren continues to increase, and more than 5.7 million grandchildren in the United States were living with and being provided for by grandparents in 2014 (U.S. Census Bureau, 2014). Although there are benefits to being placed in grandparent care, there are also challenges. Some of the challenges custodial grandparents face are health concerns, financial resources, and changes in social supports and occupational roles (Marken & Howard, 2014). Grandchildren may have …

Il-15/Il-15rα Heterodimeric Complex As Cancer Immunotherapy In Murine Breast Cancer Models, Siqi Guo, Ronald B. Smeltz, Anthony Nanajian, Richard Heller

Bioelectrics Publications

Interleukin 15 (IL-15) has been evaluated as a potential treatment for solid tumors in clinical trials, but the effectiveness of systemic IL-15 administration as a monotherapy has not been realized. IL-15 receptor alpha (IL-15Rα) can stabilize IL-15 and enhance its bioactivity. The goal of this study was to examine the activity of IL-15/IL-15Rα complex (IL-15cx) to CD8(+) T cells and evaluate its potential efficacy in murine breast cancer models. The antitumor efficacy was studied in mouse mammary carcinoma models (Her2/neu transgenic and 4T1-luc mammary cancers) treated with systemic recombinant protein with/without the depletion of myeloid-derived suppressor cells or intra-tumoral gene …

Connexin Hemichannel Activation By S-Nitrosoglutathione Synergizes Strongly With Photodynamic Therapy Potentiating Anti-Tumor Bystander Killing, Chiara Nardin, Chiara Peres, Sabrina Putti, Tiziana Orsini, Claudia Colussi, Flavia Mazzarda, Marcello Raspa, Ferdinando Scavizzi, Anna Maria Salvatore, Francesco Chiani, Abraham Tettey-Matey, Yuanyuan Kuang, Guang Yang, Mauricio A. Retamal, Fabio Mammano

Bioelectrics Publications

In this study, we used B16-F10 cells grown in the dorsal skinfold chamber (DSC) preparation that allowed us to gain optical access to the processes triggered by photodynamic therapy (PDT). Partial irradiation of a photosensitized melanoma triggered cell death in non-irradiated tumor cells. Multiphoton intravital microscopy with genetically encoded fluorescence indicators revealed that bystander cell death was mediated by paracrine signaling due to adenosine triphosphate (ATP) release from connexin (Cx) hemichannels (HCs). Intercellular calcium (Ca²⁺) waves propagated from irradiated to bystander cells promoting intracellular Ca²⁺ transfer from the endoplasmic reticulum (ER) to mitochondria and rapid activation of …

Food Allergy Bullying As Disability Harassment: Holding Schools Accountable, D'Andra Millsap Shu

University of Colorado Law Review

Millions of American schoolchildren of all ages suffer from food allergies, and increasingly, bullies target these children because of their allergies. If a bully exposes a victim to an allergen, food allergy bullying can sicken or kill within minutes. Food allergy bullying is already responsible for many hospitalizations and at least one death. Most food allergy bullying happens at school, and schools play a crucial part in addressing and preventing bullying. All too often, though, schools fail to take appropriate action. Sovereign immunity and other obstacles insulate public schools from liability in many instances, but federal disability law may provide …

Environmental Citizen Suits And The Inequities Of Races To The Top, David E. Adelman, Jory Reilly-Diakun

University of Colorado Law Review

Environmental citizen suits were founded on the belief that empowering organizations and individuals to take legal action would provide a backstop against lax federal or state programs. Working in conjunction with the system of cooperative federalism, citizen suits were designed to uphold minimum levels of environmental protection and to provide a restraint on so called "races to the bottom" in which states compete for economic development by relaxing environmental standards. To our knowledge, no one has considered whether the geographic distribution of citizen suits could have the opposite effect-namely, that it reinforces rather than mitigates disparities in the levels of …

Critique, Ideology, And Aesthetics, Richard Thompson Ford

University of Colorado Law Review

No abstract provided.

Critical Legal Thought: The Case For A Jurisprudence Of Distribution, Paulo Borrozo

University of Colorado Law Review

No abstract provided.

From The Crisis Of Critique To The Critique Of Crisis, Ben Golder

University of Colorado Law Review

No abstract provided.

Conversations After Class: 'Becoming Critical,' Or The Steps Necessary To Achieve Critical Thought For Law Students, Daniel J. Sequeira

University of Colorado Law Review

No abstract provided.

Title Vii: What's Hair (And Other Race-Based Characteristics) Got To Do With It?, D. Wendy Greene

University of Colorado Law Review

No abstract provided.

Investigating The Effect Of Khat (Catha Edulis) On Selected Obesity Markers And Pathways In C57bl/6j Male Mice, Mustafa Ahmed Al-Shagga

Student Works (2020-2029)

In East African and South Western Arabian populations, Catha edulis (khat) is believed to suppress appetite and reduce body weight. First, this study conducted a systematic review of the literature on the effects of khat and its active alkaloid cathinone on body weight and appetite regulation. Second, this study investigated the effect of khat and cathinone on selected metabolic and histopathologic parameters and their influence on the expression of obesity-related genes in high-fat diet-induced obese mice. Forty-two male C57BL/6J mice were divided into seven groups (n= 6); normal diet control treated with vehicle (NDC), normal diet treated with 200 mg/kg …

Living Together In Precarious Times: Covid-19 In The Philippines, Gideon Lasco

Development Studies Faculty Publications

The coronavirus pandemic has laid bare the necessity—for social scientists and the rest of the public alike—of an ecological; non-anthropocentric view of the world as humans grapple with microbes; surround themselves with plants; and engage with non-human animals in ways that range from abuse to affection. This chapter uses this multispecies perspective to reflect on the Philippine experience of COVID-19; offering illustrative examples; sketching tentative insights; and concluding with a research agenda for future work.

Concert Recording 2021-10-29a, Er-Gene Kahng, Hyun Kim

Concert Recordings & Programs

[00:00]. Violin sonata no. 2 in D minor. I. Ziemlich langsam, Lebhaft ; II. Sehr labhaft ; III. Leise, einfach ; IV. Bewegt / Robert Schumann -- [32:22]. Violin sonata no. 1 in D minor. I. Allegro agitato ; II. Adagio ; III. Allegretto moderato ; IV. Allegro molto / Camille Saint-Saëns.

Application Of A Triple 15n Tracing Technique To Elucidate N Transformations In A Uk Grassland Soil, N Loick, E Dixon, Gp Matthews, C Müller, Vs Ciganda, M López-Aizpún, Ma Repullo, Lm Cardenas

School of Geography, Earth and Environmental Sciences

No abstract provided.

Journeying With Communities: A Community Engagement And Organizing Handbook For University Extension Workers, Mark Anthony Dayot Abenir, Abegail Martha S. Abelardo, Froilan A. Alipao, Melanie D. Turingan

Development Studies Faculty Publications

This handbook highlights the public and social mission of higher educational institutions (HEI) through Community Engagement; a term that brings forth the important use of Participatory Action Research (PAR) and Community Organizing for Community Development (COCD). The unique contribution of this handbook is that it specifically situates HEI Community Engagement within the unique historical context of the Philippines; thus adding a Philippine voice in the literature of Community-Engaged Scholarship (CEnS). It also provides activity exercises and case studies where readers can situate themselves and apply the theories; concepts; and tools they have learned so they can enhance the Community Engagement …

The Politicization And Polarization Of Climate Change, Williamson Grassle

CMC Senior Theses

In the mid to late 20th-century, climate change and other environmental issues were addressed on a bipartisan basis, with Republican politicians like President Richard Nixon and George H.W. Bush supporting and advancing measures to combat climate change. However, since the 1990s, climate change has become increasingly polarized, with significant polarization in the last decade. This paper dives into the causes behind climate change's politicization and polarization and what the future holds for bipartisan agreement by analyzing peer-reviewed articles, campaign contributions, news stories, political archives, and past interviews with climate experts. The analysis finds that the polarization has been driven by …

The Future Of Fashion: Corporate Social Responsibility And Essential Marketing Strategies, Taite Jorgensen

CMC Senior Theses

This paper analyzes how fast fashion has impacted future trends of the fashion industry. Due to globalization, the fast fashion industry has been able to create new norms of over-consumerism and international labor. Because of this, the fast fashion industry is able to mass produce in a way consumers have never seen before, in addition to making it all at extremely low prices. However, fast fashion brands are only able to mass produce cheap goods through unethical methodologies; these methodologies include unsustainable materials and practices, inhuman labor conditions and wages, and by making sizes that exclude bigger bodies. Consumers are …

Reimagining The Black Body Through Portraiture: Interpreting The Functional And Societal Roles Of Photography And The Reconstructive Power Of Camera Technology And Photographic Images For African American Self Image, Robert Cain

CMC Senior Theses

This thesis addresses the multiple ways in which the medium of photography, and specifically the portrait photograph, enabled African Americans to visually contest degrading portrayals of blackness and reclaim stolen agency in producing depictions of self throughout the media and popular culture. The societal reverberations of camera technology on the emergence of black photographers like Richard Samuel Roberts, James VanDerZee, and Gordon Parks are analyzed, and the images taken by these artists are read against a history of racist stereotypes, reconsidered for their aesthetic contributions to the art world, and interpreted within the tradition of African American photography. A brief …

“The Spirit Of Revolution:” The Impact Of Rum On The Formation Of The United States, Charles Streator

CMC Senior Theses

This thesis explores the impact of rum, be it the distillation, consumption, or trade of it, upon the formation of the American Revolution and the desire of American Colonists for independence. Through the analysis of three distinct subfactors: rum as an economic force, rum as a political tool, and the cultural and societal impacts of the rum trade and its subsequent removal from the American ethos, this project contends that rum as a commodity became a driving factor in the creation of the United States. While much has been written on the roles of stamps, sugar, and tea in the …

Medical Knowledge As A Recalcitrant Epistemological System: An Application Of Standpoint Epistemology In The Analysis Of Marginalization Within U.S Healthcare, Abby Deshazo

CMC Senior Theses

Research on healthcare disparities outside the field of epistemology tend to miss the true origins of oppressions imposed on marginalized individuals by the U.S healthcare system. This happens because of the false belief that these oppressions are reducible to social or political oppressions. By employing the perspective of a standpoint epistemologist, we can better identify the origins of these oppressions and subsequently consider more appropriate solutions. The standpoint epistemologist’s perspective (1) provides an intuitive case for the role individuals’ schemas play in the evaluation of what healthcare professionals know; (2) situates medical knowledge within epistemology, leading us to …

The Joy Of Listening: Three Voices In The Poetry Of Wisława Szymborska, Mimi Thompson

CMC Senior Theses

One of the greatest feats that a poet may achieve in his or her lifetime is to develop a voice so characteristic of themself, it would be impossible to confuse it with that of any other poet. Polish-speaking and non-Polish-speaking scholars alike have agreed that the voice of 1996 Nobel Laureate Wisława Szymborska is utterly distinct, despite the fact that her poems explore a wide range of topics and are told from multiple narrative perspectives, rarely featuring herself through any personal details. How, then, is it possible for hundreds of poems, each with their own narrator, to still be “heard” …

The Self And Memory: How Theories Of Self Are Crucial In Aiding End-Of-Life Decision Making For Dementia Patients, Eric Oregel, Eric E. Bauer

CMC Senior Theses

This paper analyzes the source of what we consider to be the self and how such conclusions should inform whether Advance Euthanasia Directives (AEDs) are valid means of exacting end-of-life decisions for patients with dementia. The paper begins with a survey aimed at investigating various popular theories of self and ultimately arrives at John Locke’s memory-based theory of personal identity as the most promising of such arguments. I then address two important critiques of the theory, the branching problem, and the various issues that arise in cases concerning significant memory loss. Ultimately, I analyze the use of Alternative Euthanasia Directives …

On The Wrongs Of Fake News, Samuel Fiske

CMC Senior Theses

While fake news has become a hot political issue in the past years, it presents novel and apolitical philosophical problems that are often neglected. This paper explores the epistemic and moral wrong of fake news, drawing on work from Immanuel Kant, Seana Shiffrin, and Miranda Fricker to explain exactly why fake news is so problematic. I argue that creating and sharing fake news violates Kant’s Categorical Imperative because it cannot be willed into a universal law and because it fails to respect rational agents as ends in themselves. I also argue that fake news presents distinct epistemic harms as it …

Agro-Environmental Approaches To The Moderation Of Outmigration From Northeast Thailand, Megan Perron

CMC Senior Theses

Thailand’s increasing migration rates out of the country’s poorest region over the past few decades have resulted in a range of issues for both migrants and relatives of the migrants who choose to remain at home. A combination of rapid urban growth in Bangkok and a declining agricultural sector in the Northeast, driven by climate change and unsustainable farming practices, is driving rural-to-urban migration that subjects them to harsh working conditions and social marginalization. To attract migration back to Isaan, the implementation of Climate-Smart Agriculture in the near term and eventually, Regenerative Agriculture, will likely build climate resilience in the …

On The Total Communicative Efficacy Of Music And Its Synthesis To Written Word Through Bob Dylan And Kendrick Lamar, Skyler Addison

CMC Senior Theses

In a social conversation, words spoken carry less than 35% of the interaction’s social meeting, with 65% conveyed by the non-verbal. While poetry relies on the word and it's subtext, songwriting may also weld the other 65%. By dissecting the dynamic communicative aspects of song, modern poets may find useful ways in which they can make their lines have more staying power with the listener, encompassing both the rhythmic catchiness of their lines to an all-encompassing emotive transfer. We may isolate the interwoven components of a song that dictate how a story is told in order to better understand how …

Didactic Democracy: Rethinking The Roles Of Individuality, Political Freedoms And “Cultural Values” In The Process Of Development, Sabrina Hartono

CMC Senior Theses

Working off of Amartya Sen’s “Development as Freedom,” this paper challenges the conception of political freedoms and their instrumental, constructive and intrinsic roles in the development of society. I explore how identity formation is not as individualistic as Sen implicitly assumes in his framework. Using Elizabeth Anderson’s work on the importance of community in developing an individual identity, as well as incorporating ideas from Marx and Somers, I argue that there is strong reason to believe that Sen’s emphasis on the instrumental and constructive roles of political freedoms is exaggerated. I challenged Sen’s conception of the intrinsic value of political …

‘It’S Like Baking A Cake’: An Analysis Of Conscience Voting In The New Zealand House Of Representatives Since The Introduction Of The Mixed-Member Proportional System In 1996, Harrison Hosking

CMC Senior Theses

Conscience voting in the New Zealand House of Representatives offers a unique opportunity to assess Sam Peltzman’s ‘Principal-Agent Theory’ as outlined in his 1984 paper, Constituent Interest and Congressional Voting.

This thesis begins with a brief assessment of the principal-agent model (and other literature regarding parliamentary representation) before looking at the New Zealand Parliamentary system and the phenomenon of private member’s bills and how they aid the legislative process. This is followed by an exploration of a constructed dataset of conscience votes that have occurred since the inception of the mixed-member proportional (MMP) electoral system in 1996. An analysis …

Prevalence Of Asymptomatic P. Falciparum Gametocyte Carriage Among School Children In Mbita, Western Kenya And Assessment Of The Association Between Gametocyte Density, Multiplicity Of Infection And Mosquito Infection Prevalence., Victor A. Mobegi, Jeremy K. Herren, Abdoulie O. Touray, Fred Wamunyokoli, Hellen Butungi

All Peer-Reviewed Publications

Background: Asymptomatic Plasmodium falciparum gametocyte carriers are reservoirs for sustaining transmission in malaria endemic regions. Gametocyte presence in the host peripheral blood is a predictor of capacity to transmit malaria. However, it does not always directly translate to mosquito infectivity. Factors that affect mosquito infectivity include, gametocyte sex-ratio and density, multiplicity of infection (MOI), and host and vector anti-parasite immunity. We assess the prevalence of gametocyte carriage and some of its associated risk factors among asymptomatic schoolchildren in Western Kenya and to further analyse the association between gametocyte density, multiplicity of infection (MOI) and mosquito infection prevalence. Methods: P. falciparum …

Affordable Processing Of Edible Orthopterans Provides A Highly Nutritive Source Of Food Ingredients, Forkwa Tengweh Fombong, John Kinyuru, Jeremiah Ng’Ang’A, Monica Ayieko, Chrysantus Mbi Tanga, Jozef Vanden Broeck, Mik Van Der Borght

All Peer-Reviewed Publications

Edible orthopterans (grasshoppers, crickets, and locusts) are major delicacies, especially across sub-Saharan Africa. Their promotion as food ingredients is increasingly gaining momentum. This study evaluates the nutritional profiles of three widely consumed orthopterans: Gryllus bimacu-latus, Locusta migratoria, and Schistocerca gregaria after blanching and oven-drying. All three species had high protein (65.3, 54.2, and 61.4% on a dry matter (DM) basis for G. bimaculatus, L. migratoria, and S. gregaria, respectively) and fat contents. Oleic (22.9–40.8%) and palmitic (26.1–43.0%) were the two most abundant fatty acids. All essential amino acids (in mg/100 g protein) were present, with glutamic acid (120–131), alanine (90.2–123), …