Digital Commons Network^™

Sensitization To A Milk Allergen Induces Differential Behavioral And Neurological Responses In Allergic C57bl/6j And Balb/Cj Mice, Nicholas Smith

Theses and Dissertations

Studies have highlighted an association between food allergies and neuropsychiatric disorders such as anxiety, depression, and attention deficit hyperactivity disorder. Though the precise mechanism behind this relationship is unknown, it marks a potential novel therapeutic strategy outside of traditional neuropharmacological intervention. Food allergy is a heterogeneous disorder of the immune system characterized by an immune response that occurs reproducibly to a given food. Chronic allergen exposure in patients with mild or non-anaphylactic food allergies may cause or exacerbate psychiatric conditions. However, the variability in food allergies due to factors like genetic background introduces selection bias for individuals with overt anaphylactic …

Closing The Loop In Life Support Systems For Spaceflight And Habitation: Reutilization Of Human Excrement Through Recovery Of Potable Water And Reclamation Of Waste Materials For In-Space Additive Manufacturing, Brittany Zimmerman

Theses and Dissertations

The National Aeronautics and Space Administration (NASA) solicited a need for a simplified, low-temperature, and robust method for recovery of water from human solid metabolic waste. A solution is investigated, and benchtop testing is performed to prove developmental feasibility utilizing an ionomer-membrane based dehydration approach for potable water recovery. Testing is implemented with synthetic fecal matter, wet wipes, dry wipes, and nitrite gloves to inform system design. The benchtop, closed-system, dehydration testing pulls together a trade space of materials to compare efficacy of designs.

The system aims to recover upwards of 80% of the water content in the human excrement. …

Combating The Effects Of War Remnants In Africa: A Case Of Landmines In Zimbabwe, Fradreck Jockonia Mujuru

Young African Leaders Journal of Development

The war remnants especially landmines from the Zimbabwe Liberation struggle that ended in 1980 is killing, maiming and haunting the people and animals. With these landmines, the security of the people is at risk in seven major areas: Mukumbura, Musengezi, Mazowe, Sheba forest, Rusitu, Sango and Lusuku. Zimbabwe is said to be heavily contaminated with landmines. Though the demining missions with five different organisations have kick-started their operations, minute progress has been made. Landmines are destroying the lives of people and animals creating societies unsafe for development. Zimbabwe needs to engage in accelerated demining actions. Furthermore, she needs to correct …

Market Efficiency Theory In African Markets, Boubacar Amadou

Young African Leaders Journal of Development

African financial markets accommodate fewer international investors due to several reasons including its weak status in the market efficiency hypothesis. Studies have confirmed this along the years; however, the slow but steady evolution in these markets can also be noticed. This study covers eight (8) African financial markets and tests them under weak form in the market's efficiency forms. This form has been divided into three (3) categories based on the random walk concept (RW3, RW2 and RW1). Results show that only two (2) markets – Johannesburg Stock Exchange (JSE) and Uganda Stock Exchange (USE) – were able to meet …

Fishes Of The Cypress Creek System, Tennessee River Drainage, Jeffery M. Ray, Mitchell S. Lovell, Benjamin S. Wilson, Stuart W. Mcgregor, Gary A. Hastert

Biology

Cypress Creek is a northern tributary to the Tennessee River (Pickwick Lake) in Lauderdale County, Alabama, and Wayne County, Tennessee, with a drainage area of 214 square miles. Although repeatedly sampled for fishes such as Slackwater Darter, Etheostoma boschungi, Tuscumbia Darter, E. tuscumbia, and Flame Chub, Hemitremia flammea, over the past several decades, the last comprehensive fish survey of the watershed was conducted in 1971, and changes in the fish fauna and community composition may have occurred. Historical data (1845‐ 2019) containing 5,105 records was compiled for 109 species reported at least once from the Cypress Creek system. Samples from …

The Effects Of Lycopene And The Mediterranean Diet On Prostate Cancer: A Systematic Review, Natalie Alexis Silk

PCOM Biomedical Studies Student Scholarship

Background: Prostate cancer (PCa) is one of the most widespread cancers diagnosed in men in the United States and is the second leading cause of cancer-related deaths worldwide. PCa will be a major cancer-related burden both socially and economically in the near future. It has been shown that dietary intake of natural anti-inflammatory agents are capable of inhibiting cancer progression, but due to the nature of dietary studies it is difficult to accurately conclude that diet is capable of impacting chronic diseases and mortality. This systematic review aims to collect and evaluate literature focused on PCa progression and the natural …

Arabinoxylan Structural Profiling Of Cool-Season Pasture Grasses Via High-Performance Anion-Exchange Chromatography With Pulsed Amperometric Detection (Hpaec-Pad) Analysis Of Endoxylanase Digests, Glenna Erin Joyce

Theses and Dissertations--Animal and Food Sciences

Arabinoxylan (AX) is a major structural polysaccharide found in the cell walls of monocots such as cereal grains and pasture grasses. The variety of AX structural components and substitution patterns contribute to AX structural diversity between different monocot species as well as plant tissues.

The rumen is the first digestion site of masticated food material in cattle and provides 70% of energy to host through fermentation of forage. There are many species of pasture grasses that act as a forage source. Differences in AX structure found in these pasture grasses may impact rumen microbial fermentation. Understanding the AX structure of …

Predicting Tomorrow: Optimizing The Early Detection Of Disease And Disease Recovery In Dairy Calves Using Precision Technologies, Melissa Cantor

Theses and Dissertations--Animal and Food Sciences

The leading causes of morbidity and mortality in preweaned dairy calves are diarrhea and bovine respiratory disease complex (BRD). The delayed detection of these diseases in calves can also delay intervention and disease recovery. The overarching objective of this dissertation was to follow a cohort of calves daily for the first 90 days of life for naturally occurring clinical BRD bouts and diarrheal bouts. The objective answered if feeding behaviors and activity levels were different in at-risk calves during BRD development and BRD recovery from an antimicrobial intervention. Furthermore, the potential of colostrum replacer as a feeding intervention strategy to …

Influence Of Dietary Manipulation On The Relationship Between Temperament Measures And Growth In Beef Cattle: Endophyte Exposure, Phytogenic Supplementation, And Controlled Feeding, Paul Shanks

Theses and Dissertations--Animal and Food Sciences

The influence of dietary factors (including endophyte exposure, phytogenic supplementation, and controlled feeding) on relationships between exit velocity (EV), growth performance in grazing and finishing cattle, and carcass characteristics were explored. Two grazing studies were conducted evaluating EV effects on cattle grazing both toxic and nontoxic endophyte-infected tall fescue. Cattle were followed through two subsequent finishing studies and an additional beef cattle finishing beef cattle study was also conducted. Results from these studies agree with many literature reports indicating that EV measures relate to growth performance and associated carcass traits in beef cattle being fed high energy diets in confinement, …

Impact Of Mineral Supplementation On Intake Behavior And Blood Flow In Growing Beef Cattle Exposed To Fescue-Derived Alkaloids, Hannah Marie Herzing

Theses and Dissertations--Animal and Food Sciences

Consumption of endophyte-infected tall fescue by cattle has repeatedly been shown to negatively impact dry matter intake (DMI), growth rate, and circulating prolactin concentrations. The objective of the current study was to determine if a mineral supplementation would mitigate the negative effects of fescue-derived alkaloid consumption on feed intake, circulating prolactin, and the vascular system. Twelve Angus crossbred steers were used in a triplicated Latin square design consisting of three 28 d experimental periods. Treatments consisted of three top-dressed mineral supplements (142 g/head/d): a non-medicated control (CON), commercially available Fescue EMT® Mineral Defense (EMT), and a test prototype (EMT 2). …

The Effects Of Form Of Selenium On The Bovine Corpus Luteum, Uterine Endometrium, And Development Of The Conceptus, Benjamin Ryne Crites

Theses and Dissertations--Animal and Food Sciences

Widespread regions of the southeast United States have soils deficient in selenium (Se), necessitating Se supplementation to cattle grazing in these areas. Adequate dietary Se is required for optimal immune function, growth, and fertility. In forages, Se is predominantly found in the organic form (OSe), which is known to increase bioavailability. However, the inorganic form (ISe) is typically found in commercial mineral mixes. We previously reported that supplementation with an isomolar 1:1 mix (MIX) of ISe (sodium selenite, Prince Se Concentrate; Prince Agri Products, Inc., Quincy, IL) and OSe (SEL-PLEX, Alltech Inc., Nicholasville, KY) increases early luteal phase concentrations of …

Monocyte Abundance And White Blood Cell Expression Of Prolactin And Nf-Kb Pathway Genes In Beef Steers Are Altered By Grazing Toxic Endophyte-Infected Tall Fescue And Lipopolysaccharide Challenge, Cecilia Winfrey

Theses and Dissertations--Animal and Food Sciences

Experiment 1 tested the hypothesis that ad libitum consumption of a 1:1 blend (MIX) of sodium selenite (ISe) and SELPLEX vs solely ISe as selenium (Se) supplements (27 ppm) in a vitamin-mineral mix (V-M) by steers subjected to summer-long grazing of toxic endophyte-infected tall fescue (TE) would ameliorate the negative effects of TE by positively affecting the expression pattern of prolactin (PRL) and NF-kB pathway genes by circulating leukocytes (WBC). Experiment 2 tested the hypothesis that the MIX form of supplemental Se also would ameliorate the negative effects of in vitro blood lipopolysaccharide challenge (LPS) on WBC gene expression. The …

Impact Of Feeding Foods Containing Industrial Hemp-Derived Cannabidiol On Canine Health And Well-Being, Elizabeth M. Morris

Theses and Dissertations--Animal and Food Sciences

Anecdotal evidence of beneficial behavioral and health effects of cannabidiol (CBD) use in companion animals has amplified the need to elucidate safety and potential impacts of CBD use. The purpose of this investigation was to determine the impact of industrial hemp-derived CBD administration on canine health and well-being. We hypothesized that CBD would produce beneficial effects on canine behavior without negatively impacting animal health. Dog treats were formulated to include CBD and shown to be palatable across a range of CBD inclusion levels. Dogs were supplemented with CBD treats and subjected to a noise-induced fear response test to assess potential …

The Role Of The Gut Microbiome In Autoimmune Disorders, Sierra Baxter

Physician Assistant Scholarly Project Posters

According to the National Institute of Health (NIH), it is estimated that over 24 million Americans are diagnosed with autoimmune disorders, and the cases are increasing (2005). A significant risk factor that has been linked to the formation of these diseases is the gut microbiome. The gut microbiome of the adult plays a vital role in the efficacy of the immune system. The purpose of this research and systematic literature review is to determine how the gut microbiome can influence autoimmune disorders. In this review, five databases were searched including PubMed, DynaMed, Cochrane Library, Embase, and Clinical Key. A variety …

P.M. Dosing Outcomes Of Ace Inhibitors Or Angiotensin Ii Receptor Blockers In Hypertension Versus P.M. Dosing In Hypertension With Comorbidities, Savana Kramer

Physician Assistant Scholarly Project Posters

• Introduction: The purpose of this research is to compare P.M. dosing outcomes of angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) in those with hypertension and hypertension plus chronic kidney disease or diabetes.

• Research Methods: Three databases were searched including PubMed, ClinicalKey, and DynaMed with a time frame of 15 years. Studies chosen for review were peer reviewed, and included randomized control trials, systematic reviews, meta-analyses, and a preclinical animal trial.

• Discussion: The research shows evidence of reduced blood pressures throughout the night and into the next day, decreased proteinuria, and decreased cardiovascular events when …

Transcriptomic Analysis Of Young Regenerating Magnocellular Neurons (Mcns) Vs Mature Non- Regenerating Mcns, Malak Alzidaneen

Theses and Dissertations

Mature mammalian CNS neurons do not regenerate or recover following injuries. Different transcription factors have been linked to axonal growth and survival, and regulation changes in these transcription factors will affect the expression levels of genes involved in axonal regeneration. A robust collateral sprouting response within the distant terminal field of magnocellular neurons, the neurohypophysis, arising from the contralateral non-injured supraoptic neurons have been shown in response to unilateral denervation of MCNs tracts. This response peaked at age 35 days then it was followed by a complete loss of the regenerative capacity between 35 days and 125 days of age. …

The Effect Of Fatty Acid-Binding Protein 1 Gene Ablation On Brain And Liver Lipid Metabolism, Regan Clarice Lawrence

Theses and Dissertations

Although studies in animal and cell culture systems have demonstrated the importance of liver fatty acid-binding protein (FABP1) in liver lipid metabolism, the impact of Fabp1 gene ablation on brain fatty acid uptake and lipid metabolism in intact animals is unknown. To address this, we assessed the effect of Fabp1 gene ablation on uptake and esterification of [1-14C]20:4n-6 into liver and brain lipids in vivo using a steady-state kinetic model. Plasma radioactivity was increased in Fabp1 gene-ablated mice, suggesting that loss of FABP1 impairs hepatic uptake of 20:4n-6. Indeed, liver uptake of [1-14C]20:4n-6 into aqueous and organic fractions was reduced. …

Enzymatic Approach To Improve Tensile, Freeness And Brightness, Yao Ntifafa

Theses and Dissertations

Weak tensile strength is usually source of web breaks on paper machines and converting machines. Web break, in general, is due to poor hydrogen bonding between the fibers. Web break which is ultimately a downtime and a waste can be reduced through enzymatic approach. In order to increase the tensile strength of the paper, it necessary to determine the amount and the conditions in which the enzymes yield a better sheet strength.A central composite design approach, using dosage, time and temperature as factors, was used to study the effects of the enzymes on the sheet strength; the pulp used is …

Panpsychism And The First-Person Perspective: The Case For Panpsychist Idealism, Brentyn Ramm

Theology Papers and Journal Articles

In this paper I argue for a version of panpsychist idealism on first-person experiential grounds. As things always appear in my field of consciousness, there is prima facie } empirical support for idealism. Furthermore, by assuming that all things correspond to a conscious perspective or perspectives (i.e., panpsychism), realism about the world is safeguarded without the need to appeal to God (as per Berkeley's idealism). Panpsychist idealism also has a phenomenological advantage over traditional panpsychist views as it does not commit perceptual experience to massive error by denying that perceived colors are properties of things. Finally, I argue that the …

Preperitoneal Insufflation Pressure Of The Abdominal Wall In A Porcine Model, Riley E. Reynolds, Benjamin Wankum, Sean J. Crimmins, Mark A. Carlson, Benjamin S. Terry

Department of Mechanical and Materials Engineering: Faculty Publications

Background Most complications and adverse events during laparoscopic surgery occur during initial entry into the peritoneal cavity. Among them, preperitoneal insufflation occurs when the insufflation needle is incorrectly placed, and the abdominal wall is insufflated. The objective of this study was to find a range for static pressure which is low enough to allow placement of a Veress needle into the peritoneal space without causing preperitoneal insufflation, yet high enough to separate abdominal viscera from the parietal peritoneum.

Methods A pressure test was performed on twelve fresh porcine carcasses to determine the minimum preperitoneal insufflation pressure and the minimum initial …

The Doctrinal Basis Of Islamic Utterances Associated With Domestic Assaults, William Andrew Arthur Gawthrop

Walden Dissertations and Doctoral Studies

AbstractBetween March 1977, and February 2020, there have been 78 instances of ideologically motivated murders and attempted murders in the United States. These instances were characterized as individual-based attacks against other individuals and treated as local crime. However, in each instance, there were indications of Islamic religious overtones characterized by Islamic religious utterances made by the attackers. The overall problem addressed in this study was the lack of research on the utterances associated with religiously based autonomous self-actualization resulting in homicides and assaults: jihad applied as street crime. The key research questions are: What are the utterances associated with Islamic-based …

The Effect Of Coding Classes On Mathematics Achievement Of Preschool Students, Ebru Hacer Erbilgin

Walden Dissertations and Doctoral Studies

The problem that inspired this study is that Turkish students’ mathematics rankings on global exams such as The Program for the International Students Assessment (PISA) and Trends in International Mathematics and Science Study (TIMMS) had been below the average for many years, a problem that may have rooted in children’s early experiences with mathematics. The purpose of this quantitative pretest posttest quasi-experimental control group study was to determine the effect of computer-programming classes with Code Studio on mathematics scores of preschool students. Siemens’s connectivism theory for the digital age formed the foundation for this research. A single research question regarding …

Medical Practitioners’ Intention To Use Secure Electronic Medical Records In Healthcare Organizations, Omar Enrique Sangurima

Walden Dissertations and Doctoral Studies

Medical practitioners have difficulty fully implementing secure electronic medical records (EMRs). Clinicians and medical technologists alike need to identify motivational factors behind secure EMR implementation to assure the safety of patient data. Grounded in the unified theory of acceptance and use of technology model, the purpose of this quantitative, correlational study was to examine the relationship between medical practitioners’ perceptions of performance expectancy, effort expectancy, social influence, facilitating conditions, and the intention to use secure EMRs in healthcare organizations. Survey data (N = 126) were collected from medical practitioners from the northeastern United States. The results of the multiple regression …

Counselor Experiences With Clients Who Bring Emotional Support Animals To Sessions, Jennifer Reynolds

Walden Dissertations and Doctoral Studies

AbstractLimited research on emotional support animals (ESAs) has led to distorted viewpoints of ESAs and how they are used; many individuals are not utilizing ESAs appropriately, and heightened awareness of the negative uses of ESAs in media and other public sources. ESAs can be an effective intervention when working with clients during counseling sessions, but due to the limited research and the negative stigma media this intervention may not be adequately represented. The purpose of this hermeneutic phenomenological study was to explore lived experiences of counselors who allow their clients to bring ESAs to counseling session, the goal of reducing …

The Connection Between Pain, Perceived Disability, Emotional/Behavioral Problems, And Treatment Satisfaction, Penny Renee Drake

Walden Dissertations and Doctoral Studies

With more than 100 million Americans living in chronic pain (CP), there is a growing need for better and more effective pain management strategies. CP can result from an injury, disease, or an emotional or psychological issue. The purpose of this quantitative, nonexperimental study using a multiple linear regression procedure was to determine if CP patients’ perception of their disability as measured by the Personality Assessment Screener (PAS) and their emotional and/or behavioral problems as measured by the Oswestry Disability Index predict their satisfaction with their pain management regimen as measured by the researcher-produced instrument Survey of Satisfaction with Pain …

Synthesized Grounded Theory Expansion Of The Quadruple Aim In Acute Care Nursing, O. Ann Ann Fuller

Walden Dissertations and Doctoral Studies

AbstractConflation of moral and compassionate healthcare within the business model that is focused on customer service, disempowers, dehumanizes, and destabilizes nursing as well as the financial stability of healthcare. The purpose of this research was to determine nurses’ perceptions of how their work environment supported or contradicted a potential expansion of the quadruple aim. The quadruple aim was the primary conceptual framework for this research. The overarching research question was about how the environment of care supports professional nurses’ provision of high-quality person- centered care and bolsters meaningful and purposeful careers. The synthesized grounded theory methodology was used to collect …

An Alternative Sudoku Puzzle With Letters While Addressing Math Anxiety, Joseph M. Furner Ph.D.

Transformations

Math anxiety remains a critical issue affecting student performance and confidence across grade levels throughout the world. This paper looks at the impact of math anxiety on students and also how using letters instead of numbers with Sudoku puzzles can perhaps alleviate math anxiety and number anxiety as an alternative to doing Sudoku puzzles and turning students on to the logic of magic squares and Sudoku puzzles. This paper shares data on math anxiety levels by grade level from a study, provides some examples of some Sudoku puzzles with Greek letters and our English alphabet along with much research, and …

W(H)Ither Judgment, Elias Leake Quinn

Cardozo Law Review de•novo

Textualists complain that loose rules of statutory interpretation inject uncertainty and inconsistency into judicial resolutions of statutory ambiguity. But by employing an incomplete theory of meaning, pure textualists fail to shore up their decisions. And by disparaging the judgement necessary to navigate complex questions of meaning, they erode trust in the judicial process—the very foundation of the rule of law.

The Unconstitutionality Of State Bans On Marriage Between First Cousins, Rachel Frommer

Cardozo Law Review de•novo

A majority of jurisdictions in the United States severely limit or prohibit the right of first cousins to marry, cohabit, or have intercourse. Yet, unlike regulation of other relationships within close degrees of consanguinity, for instance between parents and children or siblings, these statutes are relatively recent additions to the marriage regulation landscape. These bans are unsupported by the commonly-cited concerns of harmful genetic or societal consequences. First cousin-marriages are, instead, popular and permitted in much of the world—as they once were in the United States. This Article demonstrates that the prohibitions against first-cousin marriages directly contravene right-to-marry jurisprudence and …

Is It All About Efficiency? Exploring Students’ Conceptualizations Of Sustainability In An Introductory Energy Course, Laura A. Gelles, Joel Alejandro Mejia, Susan M. Lord, Gordon D. Hoople, Diana A. Chen

School of Engineering: Faculty Scholarship

Engineers are increasingly called on to develop sustainable solutions to complex problems. Within engineering, however, economic and environmental aspects of sustainability are often priori- tized over social ones. This paper describes how efficiency and sustainability were conceptualized and interrelated by students in a newly developed second-year undergraduate engineering course, An Integrated Approach to Energy. This course took a sociotechnical approach and emphasized modern energy concepts (e.g., renewable energy), current issues (e.g., climate change), and local and personal contexts (e.g., connecting to students’ lived experiences). Analyses of student work and semi-structured interview data were used to explore how students conceptualized sustainability …