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2020

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Open Drug Discovery Of Anti-Virals Critical For Canada’S Pandemic Strategy, Tania M. Bubela, E. Richard Gold, Vivek Goel, Max Morgan, Karen Mossman, Jason Nickerson, David Patrick, Aled Edwards Dec 2020

Open Drug Discovery Of Anti-Virals Critical For Canada’S Pandemic Strategy, Tania M. Bubela, E. Richard Gold, Vivek Goel, Max Morgan, Karen Mossman, Jason Nickerson, David Patrick, Aled Edwards

Office of the Provost

In the event of the current COVID-19 pandemic and in preparation for future pandemics, open science can support mission-oriented research and development, as well as commercialization. Open science shares skills and resources across sectors; avoids duplication and provides the basis for rapid and effective validation due to full transparency. It is a strategy that can adjust quickly to reflect changing incentives and priorities, because it does not rely on any one actor or sector. While eschewing patents, it can ensure high-quality drugs, low pricing, and access through existing regulatory mechanisms. Open science practices and partnerships decrease transaction costs, increase diversity …


Toward Non-Invasive Measurement Of Atmospheric Temperature Using Vibro-Rotational Raman Spectra Of Diatomic Gases, Tyler Capek, Jacek Borysow, Claudio Mazzoleni, Massimo Moraldi Dec 2020

Toward Non-Invasive Measurement Of Atmospheric Temperature Using Vibro-Rotational Raman Spectra Of Diatomic Gases, Tyler Capek, Jacek Borysow, Claudio Mazzoleni, Massimo Moraldi

Michigan Tech Publications, Part 1

We demonstrate precise determination of atmospheric temperature using vibro-rotational Raman (VRR) spectra of molecular nitrogen and oxygen in the range of 292–293 K. We used a continuous wave fiber laser operating at 10 W near 532 nm as an excitation source in conjunction with a multi-pass cell. First, we show that the approximation that nitrogen and oxygen molecules behave like rigid rotors leads to erroneous derivations of temperature values from VRR spectra. Then, we account for molecular non-rigidity and compare four different methods for the determination of air temperature. Each method requires no temperature calibration. The first method involves fitting …


Scattering Of Goldstone Bosons And Resonance Production In A Composite Higgs Model On The Lattice, V Drach, T Janowski, C Pica, S Prelovsek Dec 2020

Scattering Of Goldstone Bosons And Resonance Production In A Composite Higgs Model On The Lattice, V Drach, T Janowski, C Pica, S Prelovsek

School of Engineering, Computing and Mathematics

No abstract provided.


Tennessee Board Of Regents – System Office For The Years Ended June 30, 2019, And June 30, 2018, Tennessee. Comptroller Of The Treasury Dec 2020

Tennessee Board Of Regents – System Office For The Years Ended June 30, 2019, And June 30, 2018, Tennessee. Comptroller Of The Treasury

Financial and Compliance Audit Reports

No abstract provided.


1. Test Data, Zhiqu Lu, Likun Zhang, Lei Cao Dec 2020

1. Test Data, Zhiqu Lu, Likun Zhang, Lei Cao

Gulf Research Program Data Sets

This data set contains recorded and processed bubble sounds under different conditions: a few bubbles vs. constant flow bubbles. Each condition is tested with nitrogen and with methane.


2. Modeling, Zhiqu Lu, Likun Zhang, Lei Cao Dec 2020

2. Modeling, Zhiqu Lu, Likun Zhang, Lei Cao

Gulf Research Program Data Sets

This data set contains the results for acoustic bubble modeling.


3. Localization, Zhiqu Lu, Likun Zhang, Lei Cao Dec 2020

3. Localization, Zhiqu Lu, Likun Zhang, Lei Cao

Gulf Research Program Data Sets

This data set contains the results for oil leakage source localization.


4. Metadata Files, Zhiqu Lu, Likun Zhang, Lei Cao Dec 2020

4. Metadata Files, Zhiqu Lu, Likun Zhang, Lei Cao

Gulf Research Program Data Sets

This data set contains all ReadMe files for test data, modeling data, and localization data, as well as the corresponding codes.


5. Programs And Algorithms, Zhiqu Lu, Likun Zhang, Lei Cao Dec 2020

5. Programs And Algorithms, Zhiqu Lu, Likun Zhang, Lei Cao

Gulf Research Program Data Sets

This data set contains all codes for the study.


6. Supplemental Materials, Zhiqu Lu, Likun Zhang, Lei Cao Dec 2020

6. Supplemental Materials, Zhiqu Lu, Likun Zhang, Lei Cao

Gulf Research Program Data Sets

This data set contains all conference presentations, manuscripts, technical reports, posters.


Pretrial Release Policy Portfolios: Examining Changes Over Time In States With Low Policy Activity, Madison Kristine Doyle Dec 2020

Pretrial Release Policy Portfolios: Examining Changes Over Time In States With Low Policy Activity, Madison Kristine Doyle

Theses and Dissertations

Changes in the policy process is one of the lesser explored phenomena within the field of criminal justice. A basis of knowledge about changes in various criminal justice policy processes in the U.S., could benefit scholars and practitioners alike. This thesis explores changes in content of pretrial release policy (PRP) portfolios in states with the least policy activity both within and across states over time. A thematic content analysis of PRPs from eight U.S. states (Alaska, Arkansas, Idaho, Maine, North Dakota, South Dakota, Vermont, and Wyoming) revealed how PRPs have changed in those states over time. States that had fewer …


The Effects Of Exercise On Breastmilk Composition And Supply: A Critical Literature Review, Jewell Mcroy Dec 2020

The Effects Of Exercise On Breastmilk Composition And Supply: A Critical Literature Review, Jewell Mcroy

Masters Theses, 2020-current

It is well established that breastfeeding provides dual benefits to both the mother and the infant and is the preferred method of providing nutrients to infants essential for growth and development. Participating in regular physical exercise is also well-supported by research to be beneficial to one’s overall health and quality of life. Currently there are no physical activity guidelines developed for women who are postpartum and breastfeeding. An online database search was conducted; three articles met the inclusion criteria and were included within the review. Studies were included if there were direct measures of human breastmilk composition, supply/volume, and included …


Analytical And Clinical Sample Performance Characteristics Of The Onclarity Assay For The Detection Of Human Papillomavirus, Stephen Young, Laurence Vaughan, Karen Yanson, Karen Eckert, Aojun Li, James Harris, Aaron Ermel, James A. Williams, Mohammad Al-Ghoul, Catherine L. Cammarata, Stephanie N. Taylor, Ronald Luff, Charles K. Cooper, Barbara Van Der Pol Dec 2020

Analytical And Clinical Sample Performance Characteristics Of The Onclarity Assay For The Detection Of Human Papillomavirus, Stephen Young, Laurence Vaughan, Karen Yanson, Karen Eckert, Aojun Li, James Harris, Aaron Ermel, James A. Williams, Mohammad Al-Ghoul, Catherine L. Cammarata, Stephanie N. Taylor, Ronald Luff, Charles K. Cooper, Barbara Van Der Pol

Pathology Research and Scholarship

The objective of this study was to determine the result reproducibility and performance of the BD Onclarity human papillomavirus (HPV) assay (Onclarity) on the BD Viper LT platform using both contrived and clinical specimens. Reproducibility was assessed in BD SurePath liquid-based cytology (LBC) medium (SurePath) using contrived panels (HPV genotype 16 [HPV16] positive, HPV18 positive, or HPV45 positive) or clinical specimens (HPV16, -18, -31, -33/58, -45, or -52 positive or HPV negative). In addition, specimens from 3,879 individuals from the Onclarity trial were aliquoted prior to or following cytology processing and tested for HPV. Finally, specimens were collected using either …


Growth Strategies Through Mergers And Acquisitions In Knowledge-Based Companies – The Case For Architect/Engineer (A/E) Professional Service Firms (Psfs), Terry A. Ruhl Dec 2020

Growth Strategies Through Mergers And Acquisitions In Knowledge-Based Companies – The Case For Architect/Engineer (A/E) Professional Service Firms (Psfs), Terry A. Ruhl

College of Business Theses and Dissertations

Analyses of mergers and acquisitions (M&A) across industries are prevalent in the literature. Yet, this research reveals that at least half, if not more, of all M&A activity fails to meet strategic, operational, and financial objectives, and can result in declining employee and customer satisfaction. The research herein develops a model framework for alternative growth strategies in the architecture/engineering (A/E) industry, with a specific focus on the antecedents of successful M&A among A/E professional service firms (PSFs).At the center of the model is the Resource Based View of the Firm, where leadership capacity, cash, and capital flows yield an affordable …


Efficient Alternative Food Systems For Earth And Space, Kyle A. Alvarado Dec 2020

Efficient Alternative Food Systems For Earth And Space, Kyle A. Alvarado

Engineering

Alternative foods are a source of human-edible calories derived from an unconventional source or process. This thesis includes two alternative foods: (i) crops grown under low-tech greenhouses in low sunlight environments and (ii) hydrogen-oxidizing bacteria (HOB) in space and Earth refuges, such as to repopulate the Earth. The purpose of alternative foods is to ensure food security for human survival. During a global catastrophic risk (GCR) scenario, such as nuclear winter or super volcanic eruption, the sun may be obscured, causing lack of crop production and therefore global food shortages. The purpose of this thesis was to improve the cost …


Uncertainty Quantification In Unconventional Reservoirs Using Conventional Bootstrap And Modified Bootstrap Methodology, Chukwuemeka Okoli Dec 2020

Uncertainty Quantification In Unconventional Reservoirs Using Conventional Bootstrap And Modified Bootstrap Methodology, Chukwuemeka Okoli

Engineering

Various uncertainty quantication methodologies are presented using a combination of several deterministic decline curve analysis models and two bootstrapping algorithms. The bootstrapping algorithms are the conventional bootstrapping method (CBM) and the modied bootstrapping method (MBM). The combined deterministic-stochastic combination models are applied to 126 sample wells from the Permian basin. Results are presented for 12 to 72 months of production hindcast given an average well production history of 120 months. Previous researchers used the Arps model and both conventional and modied bootstrapping with block re-sampling techniques to reliably quantify uncertainty in production forecasts. In this work, we applied both stochastic …


Development Of A Vertical Oscillator Energy Harvester: Design And Testing Of A Novel Renewable Resource Power Conversion System, Michael A. Wise Dec 2020

Development Of A Vertical Oscillator Energy Harvester: Design And Testing Of A Novel Renewable Resource Power Conversion System, Michael A. Wise

Engineering

Remote Alaska communities have historically dealt with elevated electric power expenses due to high cost of transporting diesel fuel for power generation. To offset this cost, the installation of various renewable resources have been utilized, particularly wind and solar power. Hydrokinetic generation by harnessing river flows is an emerging and less commonly implemented renewable resource that offers great potential for power generation. Specifically, this study investigates the behavior of a novel concept for harnessing vertical oscillation that occurs when a bluff body is inserted into a flow path. Unlike traditional rotating turbines used in hydrokinetic energy, this particular device utilizes …


Threat, Opportunity, Cooperation, And Competition: Defining China's Integration Into The Arctic, Susan Elizabeth Bowman Dec 2020

Threat, Opportunity, Cooperation, And Competition: Defining China's Integration Into The Arctic, Susan Elizabeth Bowman

Arctic and Northern Studies

Despite widespread attention to China's interest in the Arctic, little research examines how the country approaches the region. This thesis uses an inductive and qualitative approach to examine China's relationships with the eight Arctic states and major international institutions in the Arctic. This thesis asks: How is China integrating into the Arctic? How do Arctic states view China's integration? Through content analysis, narratives tell the story of China's relationship with the Arctic 8 and Arctic institutions. China's integration is explored on a fundamental level through the comparison of bilateral and multilateral relations, followed by more strategic undertones including threat, opportunity, …


Comparison Of Upper Respiratory Viral Load Distributions In Asymptomatic And Symptomatic Children Diagnosed With Sars-Cov-2 Infection In Pediatric Hospital Testing Programs, Larry K Kociolek, Bijal A Parikh, Ariel Hernandez-Leyva, Et Al Dec 2020

Comparison Of Upper Respiratory Viral Load Distributions In Asymptomatic And Symptomatic Children Diagnosed With Sars-Cov-2 Infection In Pediatric Hospital Testing Programs, Larry K Kociolek, Bijal A Parikh, Ariel Hernandez-Leyva, Et Al

Open Access Publications

The distribution of upper respiratory viral loads (VL) in asymptomatic children infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unknown. We assessed PCR cycle threshold (Ct) values and estimated VL in infected asymptomatic children diagnosed in nine pediatric hospital testing programs. Records for asymptomatic and symptomatic patients with positive clinical SARS-CoV-2 tests were reviewed. Ct values were (i) adjusted by centering each value around the institutional median Ct value from symptomatic children tested with that assay and (ii) converted to estimated VL (numbers of copies per milliliter) using internal or manufacturer data. Adjusted Ct values and estimated VL …


Brian Reynolds, Public Visibility, And Gay Stardom, Finley Freibert Dec 2020

Brian Reynolds, Public Visibility, And Gay Stardom, Finley Freibert

Faculty and Staff Scholarship

Once gracing the covers of numerous gay newspapers and magazines, Brian Reynolds was a key figure of Los Angeles’ emergent gay adult film industry of the late 1960s. He had all but disappeared from gay adult film historiography until he re-emerged as a cover model for a scholarly journal in 2012, to illustrate pioneering scholarship that initiated contemporary Pat Rocco studies. This article puts the story of Brian Reynolds in dialogue with critical star studies in order to offer a recovery history of Reynolds. Reynolds’ rise to celebrity and sudden relegation to obscurity underscores the historical instability of gay pornographic …


Gender Variations In Neonatal And Early Infant Mortality In India And Pakistan: A Secondary Analysis From The Global Network Maternal Newborn Health Registry, Zubair H. Aghai, Shivaprasad S. Goudar, Archana Patel, Sarah Saleem, Sangappa M. Dhaded, Avinash Kavi, Parth Lalakia, Farnaz Naqvi, Patricia L. Hibberd, Elizabeth M. Mcclure Dec 2020

Gender Variations In Neonatal And Early Infant Mortality In India And Pakistan: A Secondary Analysis From The Global Network Maternal Newborn Health Registry, Zubair H. Aghai, Shivaprasad S. Goudar, Archana Patel, Sarah Saleem, Sangappa M. Dhaded, Avinash Kavi, Parth Lalakia, Farnaz Naqvi, Patricia L. Hibberd, Elizabeth M. Mcclure

Community Health Sciences

Background: To determine the gender differences in neonatal mortality, stillbirths, and perinatal mortality in south Asia using the Global Network data from the Maternal Newborn Health Registry.
Methods: This study is a secondary analysis of prospectively collected data from the three south Asian sites of the Global Network. The maternal and neonatal demographic, clinical characteristics, rates of stillbirths, early neonatal mortality (1-7 days), late neonatal mortality (8-28 days), mortality between 29-42 days and the number of infants hospitalized after birth were compared between the male and female infants.
Results: Between 2010 and 2018, 297,509 births [154,790 males (52.03%) and 142,719 …


Rates And Risk Factors For Preterm Birth And Low Birthweight In The Global Network Sites In Six Low- And Low Middle-Income Countries, Yamini V. Pusdekar, Archana B. Patel, Kunal G. Kurhe, Savita R. Bhargav, Vanessa Thorsten, Ana Garces, Robert L. Goldenberg, Shivaprasad S. Goudar, Sarah Saleem, Fabian Esamai Dec 2020

Rates And Risk Factors For Preterm Birth And Low Birthweight In The Global Network Sites In Six Low- And Low Middle-Income Countries, Yamini V. Pusdekar, Archana B. Patel, Kunal G. Kurhe, Savita R. Bhargav, Vanessa Thorsten, Ana Garces, Robert L. Goldenberg, Shivaprasad S. Goudar, Sarah Saleem, Fabian Esamai

Community Health Sciences

Background: Preterm birth continues to be a major public health problem contributing to 75% of the neonatal mortality worldwide. Low birth weight (LBW) is an important but imperfect surrogate for prematurity when accurate assessment of gestational age is not possible. While there is overlap between preterm birth and LBW newborns, those that are both premature and LBW are at the highest risk of adverse neonatal outcomes. Understanding the epidemiology of preterm birth and LBW is important for prevention and improved care for at risk newborns, but in many countries, data are sparse and incomplete.
Methods: We conducted data analyses using …


Maternal Mortality In Six Low And Lower-Middle Income Countries From 2010 To 2018: Risk Factors And Trends, Melissa Bauserman, Vanessa R. Thorsten, Tracy L. Nolen, Jackie Patterson, Adrien Lokangaka, Antoinette Tshefu, Archana B. Patel, Patricia L. Hibberd, Sarah Saleem, Saleem Jessani Dec 2020

Maternal Mortality In Six Low And Lower-Middle Income Countries From 2010 To 2018: Risk Factors And Trends, Melissa Bauserman, Vanessa R. Thorsten, Tracy L. Nolen, Jackie Patterson, Adrien Lokangaka, Antoinette Tshefu, Archana B. Patel, Patricia L. Hibberd, Sarah Saleem, Saleem Jessani

Community Health Sciences

Background: Maternal mortality is a public health problem that disproportionately affects low and lower-middle income countries (LMICs). Appropriate data sources are lacking to effectively track maternal mortality and monitor changes in this health indicator over time.
Methods: We analyzed data from women enrolled in the NICHD Global Network for Women's and Children's Health Research Maternal Newborn Health Registry (MNHR) from 2010 through 2018. Women delivering within research sites in the Democratic Republic of Congo, Guatemala, India (Nagpur and Belagavi), Kenya, Pakistan, and Zambia are included. We evaluated maternal and delivery characteristics using log-binomial models and multivariable models to obtain relative …


The Megaton Mission : The Role Of The Nuclear Arms Race In 1950s British Imperialism, Joseph David Daniel Holding Dec 2020

The Megaton Mission : The Role Of The Nuclear Arms Race In 1950s British Imperialism, Joseph David Daniel Holding

Lingnan Theses (MPhil & PhD)

In August 1945, the Pacific theatre of the Second World War came to a dramatic close with the United States dropped two atomic bombs on Hiroshima and Nagasaki. Following this, tensions between the United States and the Soviet Union grew tremendously and the two superpowers set about developing even more destructive bombs in case these tensions reached a breaking point. The nuclear bomb came to symbolise power in the post-war era. However, they were not the only powers with nuclear programmes in the 1950s. Churchill, and successive Conservative governments, were keen in joining the nuclear arms race. Operation Grapple was …


Como Olvidarte, Emilce Quiroz Dec 2020

Como Olvidarte, Emilce Quiroz

Capstones

Being in both the Spanish and Documentary concentrations, I had to produce a short documentary in the Spanish language and produce a piece of written work to go along with it. For my capstone, I chose to focus on a homicide case that happened in Mexico City in 2015. It caught international attention and although many people have their own thoughts and beliefs as to what happened that day, I wanted to provide a platform for the families to express their own feelings of loss, injustice, and their own versions of the truth. This case was highly distorted by the …


Greek Religion And Epigraphic Corpora: What's Sacrae About Leges Sacrae?, Laura Gawlinski Dec 2020

Greek Religion And Epigraphic Corpora: What's Sacrae About Leges Sacrae?, Laura Gawlinski

Classical Studies: Faculty Publications and Other Works

The Latin phrase leges sacrae and its various translations (sacred laws, lois
sacrées, heilige Gesetze) have been applied since at least the nineteenth cen-
tury to various collections of inscribed documents. It is a modern invention
born out of the German Wissenschaft ideology of systematic, scientific, com-
prehensive methods of inquiry. This rubric and the collecting of Greek inscrip-
tions under it have always been recognized as problematically subjective, and
in the last decade or so a flurry of scholarship has critiqued the corpora more
directly. Much of this analysis has focused on the leges half of leges sacrae:
whether …


The Cardiac Neural Crest Cells In Heart Development And Congenital Heart Defects, Eileen M Burd, Ahmed Babiker, Jessica K Fairley, Divya Bhamidipati, Laila E Woc-Colburn, Blaine A Mathison Dec 2020

The Cardiac Neural Crest Cells In Heart Development And Congenital Heart Defects, Eileen M Burd, Ahmed Babiker, Jessica K Fairley, Divya Bhamidipati, Laila E Woc-Colburn, Blaine A Mathison

Faculty, Staff and Student Publications

No abstract provided.


The George-Anne Daily, Georgia Southern University Dec 2020

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.


Large Animal Genetic Engineering Summit 2020, Irina A. Polejaeva Dec 2020

Large Animal Genetic Engineering Summit 2020, Irina A. Polejaeva

Funded Research Records

No abstract provided.


Technoference: Parent Mobile Device Use And Implications For Children And Parent-Child Relationships., Brandon T. Mcdaniel Phd Dec 2020

Technoference: Parent Mobile Device Use And Implications For Children And Parent-Child Relationships., Brandon T. Mcdaniel Phd

Health Services and Informatics Research

The increase in the prevalence of smartphones and mobile devices has spurred changes in the caregiving environment of infants and young children, as phones and mobile devices are used at times during caregiving and in caregiving spaces. This use could create disruptions and cause distractions during parenting (termed technoference). This article summarizes the potential impacts on parent responsiveness and the experiences of infants and young children. Yet, it also warns that it is important to consider the reason for and type of parent use. Finally, the article ends with practical tips for working with parents concerning mobile device use.