Digital Commons Network^™

Local Injections Of Β-Ngf Accelerates Endochondral Fracture Repair By Promoting Cartilage To Bone Conversion., Kevin O. Rivera, Fabrizio Russo, Ryan M. Boileau, Ryan E. Tomlinson, Theodore Miclau, Ralph S. Marcucio, Tejal A. Desai, Chelsea S. Bahney

Department of Orthopaedic Surgery Faculty Papers

There are currently no pharmacological approaches in fracture healing designed to therapeutically stimulate endochondral ossification. In this study, we test nerve growth factor (NGF) as an understudied therapeutic for fracture repair. We first characterized endogenous expression of Ngf and its receptor tropomyosin receptor kinase A (TrkA) during tibial fracture repair, finding that they peak during the cartilaginous phase. We then tested two injection regimens and found that local β-NGF injections during the endochondral/cartilaginous phase promoted osteogenic marker expression. Gene expression data from β-NGF stimulated cartilage callus explants show a promotion in markers associated with endochondral ossification such as Ihh, Alpl, …

Association Between Duration Of Residence And Prevalence Of Type 2 Diabetes Among Male South Asian Expatriate Workers In The United Arab Emirates: A Cross-Sectional Study, Syed Mahboob Shah, Lindsay M. Jaacks, Fatima Al-Maskari, Juma Al-Kaabi, Faisal Aziz, Elpidoforos Soteriades, Tom Loney, Hamed Farooqi, Anjum Memon, Raghib Ali

Department of Family Medicine

Expatriates account for about 80% of the total population in the United Arab Emirates (UAE). This study aimed to evaluate the hypothesis that prevalence of type 2 diabetes in male South Asian expatriates increases with increased length of residence in the UAE.
Design, settings and participants: This cross-sectional study recruited a representative sample (n=1375) of male South Asian expatriates aged ≥18 years in Al Ain, UAE. Sociodemographic, anthropometric and lifestyle data were obtained using a pilot-tested adapted version of the WHO STEPS instrument.
Main outcome measures: Duration of residence was used as a marker for acculturation. Type 2 diabetes was …

Research From Around The World: Substance Use Disorder In The Us, Peggy Compton

SigmaCast [Podcast]

This episode we will be discussing the body of nursing research from Peggy Compton, PhD, RN, FAAN, a Sigma International Nurse Researcher Hall of Fame inductee in July of 2020 and an Associate Professor and van Ameringen Endowed Chair at the University of Pennsylvania School of Nursing.

Host: Matt Howard, DNP, RN, CEN, TCRN, CPEN, CPN: Director of Scholarship Resources, Sigma

Cost Savings Of Right To Shop Programs, Tennessee. Advisory Commission On Intergovernmental Relations.

Miscellaneous Reports

No abstract provided.

Services Provided By Local Governments And The Sources Of Revenue To Fund Them, Final Installment Of Tacir's Study On Local Government Revenue And Services, Tennessee. Advisory Commission On Intergovernmental Relations.

Miscellaneous Reports

No abstract provided.

On The Effective Finite Element Simplification Of Bolted Joints: Static And Modal Analyses, Abdulrahman Mohammad Ibrahim

Theses

In this paper, the finite element simplification of a standard bolted joint configuration is investigated. Static and modal analyses of a 3D model are used for benchmarking three different simplified finite element models using Siemens NX software. More specifically, the three simplified finite element models utilize beam elements, spring elements and a coupled shell-beamspring elements model. Four margin of safety criteria with respect to slipping, gapping, yield strength and ultimate strength were evaluated. Results show comparable values in the yield and ultimate margins of safety of all three simplified finite element models. Additionally, a parametric analysis relative to bolt size …

Bioinformatics Metadata Extraction For Machine Learning Analysis, Zachary Tom

Master's Projects

Next generation sequencing (NGS) has revolutionized the biological sciences. Today, entire genomes can be rapidly sequenced, enabling advancements in personalized medicine, genetic diseases, and more. The National Center for Biotechnology Information (NCBI) hosts the Sequence Read Archive (SRA) containing vast amounts of valuable NGS data. Recently, research has shown that sequencing errors in conventional NGS workflows are key confounding factors for detecting mutations. Various steps such as sample handling and library preparation can introduce artifacts that affect the accuracy of calling rare mutations. Thus, there is a need for more insight into the exact relationship between various steps of the …

Malware Classification Using Lstms, Dennis Dang

Master's Projects

Signature and anomaly based detection have long been quintessential techniques used in malware detection. However, these techniques have become increasingly ineffective as malware becomes more complex. Researchers have therefore turned to deep learning to construct better performing models. In this project, we create four different long-short term memory (LSTM) models and train each model to classify malware by family type. Our data consists of opcodes extracted from malware executables. We employ techniques used in natural language processing (NLP) such as word embedding and bidirection LSTMs (biLSTM). We also use convolutional neural networks (CNN). We found that our model consisting of …

Commercializing Cannabis: Confronting The Challenges And Uncertainty Of Trademark And Trade Secret Protection For Cannabis-Related Businesses, John Mixon

Washington Journal of Law, Technology & Arts

Over the last couple of decades, society has become more accepting of recreational cannabis and an ever-growing number of states have passed pro-cannabis legislation. With this change, the cannabis industry has, to some extent, exploded into a booming enterprise in states that have legalized marijuana. Nonetheless, cannabis' status as a Schedule I banned substance under the Controlled Substances Act of 1970 remains unchanged. As a result, businesses in the cannabis industry face the unique challenge of having to toe the line between "legally" operating under state law and violating federal law, which trumps state law. One particular situation in which …

News Reporting On Trump's Covid-19 Treatments: Should Broadcasters Have To Disclose Their Being Potentially Dangerous?, Dr. Joel Timmer

Washington Journal of Law, Technology & Arts

During the early months of the COVID-19 pandemic in 2020, President Trump touted a number of treatments that many medical professionals considered dangerous. These treatments include hydroxychloroquine and disinfectants, which if misused could cause a patient’s death. This prompted Free Press to file an emergency petition with the FCC, arguing that broadcasters who report on Trump’s claims about these treatments without highlighting their dangers could be in violation of the Commission’s broadcast hoax rule. Free Press also requested the FCC require that broadcasters include disclaimers when reporting on such claims. This article examines whether the broadcast hoax rule has been …

Small Cell Wireless Facilities And Public Rights-Of-Way, Assessing The Effects Of Public Chapter 819, Acts Of 2018, Tennessee. Advisory Commission On Intergovernmental Relations.

Miscellaneous Reports

No abstract provided.

Critical Dialog: Response To Rachel M. Gillum’S Review Of The Politics Of The Headscarf In The United States, Bozena C. Welborne, Aubrey L. Westfall, Özge Çelik Russell, Sarah A. Tobin

Government: Faculty Publications

A Critical Dialog between the reviewer, Rachel M. Gillum, of The Politics of the Headscarf in the United States and the authors, Bozena C. Welborne, Aubrey L. Westfall, Özge Çelik Russell, and Sarah A. Tobin. Ithaca: Cornell University Press, 2018. 264p.

Brief Report: The Impact Of Disease Stage On Early Gaps In Art In The "Treatment For All" Era - A Multisite Cohort Study., Ingrid T. Katz, Nicholas Musinguzi, Kathleen Bell, Anna Cross, Mwebesa Bosco Bwana, Gideon Amanyire, Stephen Asiimwe, Catherine Orrell, David R. Bangsberg, Jessica E. Haberer

OHSU-PSU School of Public Health Faculty Publications and Presentations

Adoption of "Treat All" policies has increased ART initiation in sub-Saharan Africa; however, unexplained early losses continue to occur. More information is needed to understand why treatment discontinuation continues at this vulnerable stage in care.

Using Urban Ecology As A Transdisciplinary Approach For Teaching English Learners, Elvira G. Armas, Magaly Lavadenz, Eric G. Strauss

Cities and the Environment (CATE)

Teams from the Center for Equity for English Learners (CEEL) and the Center for Urban Resilience (CURes) at Loyola Marymount University collaborated on multi-year projects to implement the Urban Ecology for English Learners Projects designed to implement a professional learning and curriculum model to explicitly engage students in experiences where they learn science content through investigations of their local schoolyards and neighborhoods while simultaneously advancing language and literacy skills. This partnership empowers educators to leverage the interdisciplinary science of urban ecology and resilience as a way to democratize access and opportunity for English Learner students in diverse urban settings.

Native And Non-Native Sources Of Carbohydrate Correlate With Abundance Of An Invasive Ant, Lori Lach, Benjamin Hoffmann, Melinda L. Moir

Biosecurity Research Articles

Invasive species threaten many ecological communities and predicting which communities and sites are invasible remains a key goal of invasion ecology. Although invasive ants often reach high abundances in association with plant-based carbohydrate resources, the source and provenance of these resources are rarely investigated. We characterized carbohydrate resources across ten sites with a range of yellow crazy ant abundance in Arnhem Land, Australia and New Caledonia to determine whether yellow crazy ant (Anoplolepis gracilipes) abundance and trophic position correlate with carbohydrate availability, as well as the relative importance of native and non-native sources of carbohydrates to ant diet. …

Reference Gene Selection For Transcriptional Profiling In Cryptocercus Punctulatus, An Evolutionary Link Between Isoptera And Blattodea, Zhen Li, Xiangrui Li, Qingwen Zhang, Ling Yuan, Xuguo Zhou

Plant and Soil Sciences Faculty Publications

The subsocial life style and wood-feeding capability of Cryptocercus gives us an evolutionary key to unlock some outstanding questions in biology. With the advent of the Genomics Era, there is an unprecedented opportunity to address the evolution of eusociality and the acquisition of lignocellulases at the genetic level. However, to quantify gene expression, an appropriate normalization strategy is warranted to control for the non-specific variations among samples across different experimental conditions. To search for the internal references, 10 housekeeping genes from a gut transcriptome of a wood-feeding cockroach, Cryptocercus punctulatus, were selected as the candidates for the RT-qPCR analysis. The …

Does Covid-19 Contribute To Development Of Neurological Disease?, Arehally M. Mahalakshmi, Bipul Ray, Sunanda Tuladhar, Abid Bhat, Shasthara Paneyala, Duraisamy Patteswari, Meena K. Sakharkar, Hamdan Hamdan, David M. Ojcius, Srinivasa R. Bolla, Musthafa M. Essa, Saravana B. Chidambaram, M. Walid Qoronfleh

All Dugoni School of Dentistry Faculty Articles

Background: Although coronavirus disease 2019 (COVID-19) has been associated primarily with pneumonia, recent data show that the causative agent of COVID-19, the coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can infect a large number of vital organs beyond the lungs, such as the heart, kidneys, and the brain. Thus, there is evidence showing possible retrograde transmission of the virus from the olfactory epithelium to regions of the brain stem. Methods: This is a literature review article. The research design method is an evidence-based rapid review. The present discourse aim is first to scrutinize and assess the available literature on …

Motivations, Environmental Attitudes, And Personal Efficacy Of Volunteers At Communitree Tree-Planting Events In Northwest Indiana, U.S., Kaitlyn Pike, Rebecca Brokaw, Jess Vogt

Cities and the Environment (CATE)

In this paper, we examine the mechanisms of volunteering at tree-planting events conducted as part of a new, multi-organizational tree-planting effort in northwest Indiana called CommuniTree. A broad literature exists on general volunteerism as well as environmental volunteering, urban forestry volunteering, and even tree-planting volunteering. Yet, the motivations, environmental attitudes, and personal efficacy of urban forestry volunteers in particular are not fully understood, nor are the outcomes and implications of volunteer participation in neighborhood greening programs. A 22-question (34 individual items), self-report survey was administered in-person at CommuniTree tree-planting events in 2017 through 2019, obtaining 114 responses. CommuniTree volunteers who …

Messy Miracles, Joseph Khabbaz

The Main Thing Devotional

Blessed is she who has believed that the Lord would fulfill his promises to her!” - Luke 1:45

Sometimes we need our plans to fail for God’s plans to succeed.

Quantifying Deepfake Detection Accuracy For A Variety Of Natural Settings, Pratikkumar Prajapati

Master's Projects

Deep fakes are videos generated from a starting video of a person where that person's face has been swapped for someone else's. In this report, we describe our work to develop general, deep learning-based models to classify Deep Fake content. Our first experiments involved simple Convolution Neural Network (CNN)-based models where we varied how individual frames from the source video were passed to the CNN. These simple models tended to give low accuracy scores for discriminating fake versus non-fake videos of less than 60%. We then developed three more sophisticated models: one based on choosing test frames, one based on …

A Preliminary Analysis Of How A Software Organization’S Maturity And Size Affect Its Intellectual Property Portfolio, Daniel Gifford

Master of Science in Software Engineering Theses

Intellectual property, commonly known as IP, is complex. The four main types of software IP, which is what this thesis will focus on, are patents, trade secrets, trademarks, and copyright. Patents, trade secrets, and copyrights were all studied by this thesis. Software IP is unique in that it can by copyrighted. Different IP owners, which can be businesses of different types, individuals, and universities, often have different strategies as to how to use their IP portfolio. This thesis studies differences in IP usage between these entities specifically in the field of software. Large and small software companies were analyzed specifically. …

Infection-Induced 5'-Half Molecules Of Trnahisgug Activate Toll-Like Receptor 7., Kamlesh Pawar, Megumi Shigematsu, Soroush Sharbati, Yohei Kirino

Computational Medicine Center Faculty Papers

Toll-like receptors (TLRs) play a crucial role in the innate immune response. Although endosomal TLR7 recognizes single-stranded RNAs, their endogenous RNA ligands have not been fully explored. Here, we report 5'-tRNA half molecules as abundant activators of TLR7. Mycobacterial infection and accompanying surface TLR activation up-regulate the expression of 5'-tRNA half molecules in human monocyte-derived macrophages (HMDMs). The abundant accumulation of 5'-tRNA halves also occur in HMDM-secreted extracellular vehicles (EVs); the abundance of EV-5'-tRNAHisGUG half molecules is >200-fold higher than that of the most abundant EV-microRNA (miRNA). Sequence identification of the 5'-tRNA halves using cP-RNA-seq revealed abundant and selective packaging …

Scholarly Communications In Knowledge Economy By A Premier Indian Chemical Sciences R&D Laboratory - Csir-Ncl : A Scientometric Evaluation, Gati Krushna Nayak, Sudam Charan Sahu, Vaishali S. Khaparde, Sudeshna Tripathi

Library Philosophy and Practice (e-journal)

This paper made an attempt to analyze publications of CSIR-NCL, Pune a reputed world class 70 years renowned Chemistry & Chemical Engineering R&D Laboratory during the last 10 years w.e.f. 2010-2019 as reflected in SCOPUS multidisciplinary international database. The total number of 5372 research publications have been downloaded and analyzed according to the objectives. This paper gives a complete view of the evaluation of research outcomes of the CSIR-NCL, Pune the productive and influential in innovative research. This paper vigorously tries to give a complete view of the evaluation of research outcomes of the CSIR-NCL, Pune in India that ought …

State Of Idaho V. Rachel Elizabeth Luna Appellant's Brief Dckt. 47760

Not Reported

No abstract provided.

State V. Ybarra Appellant's Brief Dckt. 48016

Not Reported

No abstract provided.

State V. Scruggs Respondent's Brief Dckt. 48020

Not Reported

No abstract provided.

State V. Suckow Appellant's Brief Dckt. 48047

Not Reported

No abstract provided.

State V. Clapp Appellant's Brief Dckt. 48049

Not Reported

No abstract provided.

State V. Lake Respondent's Brief Dckt. 48057

Not Reported

No abstract provided.

State V. Mallak Respondent's Brief Dckt. 48169

Not Reported

No abstract provided.