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Systemic Vasculitides. Part 2: Small Vessel Diseases, Sean M. Conte, Peter R. Vale

Medical Papers and Journal Articles

Small vessel vasculitides often manifest as neurological, renal, pulmonary and dermatological symptoms. Clinical features of systemic vasculitides are often nonspecific; therefore, it is important that GPs be aware of the range of symptoms that can help in the differential diagnosis, treatment and management of this diverse group of conditions.

Three Tools For Managing Vertigo In The Frontline, Vincent A. Van Vugt, Allison S. Young, Andrew P. Bradshaw, Benjamin Nham, Margot Woods, Miriam S. Welgampola

Medical Papers and Journal Articles

Vertigo is a challenging symptom in general practice. With access to three tools – a focused history, eye examination and a management algorithm – a large proportion of vertiginous patients could be managed effectively by GPs. This practical guide seeks to increase the skills and confidence of frontline practitioners when managing vertigo.

The Power Of Collaborative Planning: How A Health And Planning Collaboration Facilitated Integration Of Health Goals In The 30-Year Plan For Greater Adelaide, Michael Mcgreevy, Patrick Harris, Toni Delaney-Crowe, Matt Fisher, Peter Sainsbury, Fran Baum

Medical Papers and Journal Articles

This article examines the relationship between theories of urban governance, strategic planning and collaborative planning and the preparation of a strategic spatial plan for the greater Adelaide region. In particular, it analyses the extent to which health professionals involved in the collaborative processes used to formulate the plan were able to advocate for health-related objectives. The analysis was undertaken using data collected in interviews with actors directly involved in the collaborative processes that produced the plan. Interview responses were analysed to understand how factors that can derail or conversely facilitate successful collaborative planning processes were dealt with.

The Relationship Between Demoralization And Depressive Symptoms Among Patients From The General Hospital: Network And Exploratory Graph Analysis, Martino Belvederi Murri, Rosangela Caruso, Heifa Ounalli, Luigi Zerbinati, Eleonora Berretti, Silvia Costa, Elisabetta Recla, Federica Folesani, David Kissane, Maria Giulia Nanni, Luigi Grassi

Medical Papers and Journal Articles

Introduction: Depression and demoralization are highly prevalent among individuals with physical illnesses but their relationship is still unclear.

Objective: To examine the relationship between clinical features of depression and demoralization with the network approach to psychopathology.

Methods: Participants were recruited from the medical wards of a University Hospital in Italy. The Demoralization Scale (DS) was used to assess demoralization, while the Patient Health Questionnaire-9 (PHQ-9) to assess depressive symptoms. The structure of the depression-demoralization symptom network was examined and complemented by the analysis of topological overlap and Exploratory Graph Analysis (EGA) to identify the most relevant groupings (communities) of symptoms …

Ethical Thinking Machines In Surgery And The Requirement For Clinical Leadership, Quinlan D. Buchlak, Nazanin Esmaili, Jean-Christophe Leveque, Christine Bennett, Massimo Piccardi, Farrokh Farrokhi

Medical Papers and Journal Articles

No abstract available.

Examiners' Decision‐Making Processes In Observation-Based Clinical Examinations, Bunmi S. Malau-Aduli, Richard B. Hays, Karen D'Souza, Amy M. Smith, Karina Jones, Richard Turner, Lizzi Shires, Jane Smith, Shannon Saad, Cassandra Richmond, Antonio Celenza, Tarun Sen Gupta

Medical Papers and Journal Articles

Background: Objective structured clinical examinations (OSCEs) are commonly used to assess the clinical skills of health professional students. Examiner judgement is one acknowledged source of variation in candidate marks. This paper reports an exploration of examiner decision making to better characterise the cognitive processes and workload associated with making judgements of clinical performance in exit‐level OSCEs.

Methods: Fifty‐five examiners for exit‐level OSCEs at five Australian medical schools completed a NASA Task Load Index (TLX) measure of cognitive load and participated in focus group interviews immediately after the OSCE session. Discussions focused on how decisions were made for borderline and clear …

Epidemiology Of Soccer‐Related Head Injury In Children 5–14 Years In Victoria, Australia, Amy E. Smith, Catherine Krejany, Moyez Jiwa

Medical Papers and Journal Articles

Aim: Our aim was to use epidemiological data to determine the incidence of soccer‐related head injuries in children aged 5–14 years who presented at emergency departments (EDs) or were admitted in hospitals in Victoria, Australia.

Methods: ED presentation and hospital admission de‐identified aggregate data were from the Victorian Injury Surveillance Unit. Soccer participation data were compared with the soccer‐related head injury data to determine the incidence of this injury among these children.

Results: The incidence of ED presentations was 0.17% of children participating in soccer during the study period (financial years 2011–2012 to 2015–2016). The 10–14‐years age group presented with …

Equitable Expanded Carrier Screening Needs Indigenous Clinical And Population Genomic Data, Simon Easteal, Ruth M. Arkell, Renzo F. Balboa, Shayne A. Bellingham, Alex D. Brown, Tom Calma, Matthew C. Cook, Megan Davis, Hugh J.S Dawkins, Marcel E. Dinger, Michael S. Dobbie, Ashley Farlow, Kylie G. Gwynne, Azure Hermes, Wendy E. Hoy, Misty R. Jenkins, Simon H. Jiang, Warren Kaplan, Stephen Leslie, Bastien Llamas, Graham J. Mann, Brendan J. Mcmorran, Rebekah E. Mcwhirter, Cliff J. Meldrum, Shivashankar H. Nagaraj, Saul J. Newman, Jack S. Nunn, Lyndon Ormond-Parker, Neil J. Orr, Devashi Paliwal, Hardip R. Patel, Glenn Pearson, Greg R. Pratt, Boe Rambaldini, Lynette W. Russell, Ravi Savarirayan, Matthew Silcocks, John C. Skinner, Yassine Souilmi, Carola G. Vinuesa, Gareth Baynam

Medical Papers and Journal Articles

Expanded carrier screening (ECS) for recessive monogenic diseases requires prior knowledge of genomic variation including DNA variants that cause disease. The composition of pathogenic variants differs greatly among human populations, but historically research about monogenic diseases has focused mainly on people with European ancestry. By comparison, less is known about pathogenic DNA variants in people from other parts of the world. Consequently, inclusion of currently under-represented Indigenous and other minority population groups in genomic research is essential to enable equitable outcomes in ECS and other areas of genomic medicine. Here we discuss this issue in relation to the implementation of …

Foot Burns: A Comparative Analysis Of Diabetic And Non-Diabetic Patients, Jason Diab, Justine O'Hara, Miranda Pye, Christine Parker, Peter K.M Maitz, Andrea Issler-Fisher

Medical Papers and Journal Articles

Introduction: Foot burns represent a small part of the body with many challenges. The impact of diabetes on clinical outcomes adds further issues in management that clinicians must consider in their management. These factors have serious implications on morbidity and long term sequelae. Our aim is to analyse epidemiological trends of foot burns and examine the differences between diabetic and non-diabetics at Concord hospital from 2014 to 2019.

Methods: A retrospective audit from 2014–19 at Concord General Repatriation Hospital Burns Unit summarised patient demographics, burn injury, diabetic status, operations and length of stay. All foot burn injuries from 2014–19 of …

Evaluating A Low-Fidelity Inguinal Canal Model, Jake Hindmarch, Khalil Bazzi, John Lahoud, Ali Malik, Sankar Sinha

Medical Papers and Journal Articles

Purpose: The inguinal canal anatomy is of paramount clinical significance due to the common occurrence of direct and indirect inguinal hernias. However, the inguinal canal is often an area of great difficulty for medical students to understand. The aim of this study was to evaluate the use of a low-cost, low-fidelity inguinal canal model as a teaching and learning aid.

Methods: A low-fidelity inguinal canal model was introduced as a learning aid in an anatomy tutorial on the inguinal region. Students were randomised into intervention (n=66) and control (n=40) groups. Following the tutorial, all students completed a multiple-choice question quiz …

The Relevance Of Non-Financial Key Performance Indicators, Bingxu Fang, Partha Mohanram, Dushyant Vyas

Research Collection School Of Accountancy

The limitations of financials statements in assessing firm performance have long been known to the academic and practitioner accounting communities. Recent years have witnessed a sharp increase in the frequency and scope of non-financial Key Performance Indicators (KPIs) disclosed by companies and used by market participants. In this study, we investigate the relevance of various voluntarily reported non-financial KPIs. We find that KPIs are positively associated with future profitability, sales growth, and current stock returns; however, the stock market underreacts to the information embedded in KPIs for firms operating in opaque information environments.

How Our Work Influences Who We Are: Testing A Theory Of Vocational And Personality Development Over Fifty Years, Stephen A. Woods, Grant W. Edmonds, Sarah E. Hampson, Filip Lievens

Research Collection Lee Kong Chian School Of Business

This study examines the developmental influences of occupational environments on personality traits from childhood to adulthood. We test aspects of a theory of vocational and personality development, proposing that traits develop in response to work experience following corresponsive and noncorresponsive mechanisms. We describe these pathways in the context of situations of vocational gravitation and inhabitation. In a sample from the Hawaii personality and health cohort (N = 596), we examined associations of childhood and adulthood personality traits, with occupational environments profiled on the RIASEC model. Mediations tests confirmed that work influenced personality development from childhood to adulthood for Openness/Intellect. We …

Sell-Side Analysts' Benchmarks, Ohad Kadan, Leonardo Madureira, Rong Wang, Tzachi Zach

Research Collection Lee Kong Chian School Of Business

Sell-side analysts employ different benchmarks when defining their recommendations. A buy for some brokers means the stock is expected to outperform its industry, while for other brokers it means the stock is expected to outperform the market, or some return threshold. We show that these stated benchmarks have implications for the distribution of recommendations, price reactions to recommendations, and the investment value of recommendations. We conclude that, depending on the question, academics may need to account for the benchmarks when studying analysts’ outputs, and investors may find the benchmarks beneficial in interpreting analysts’ advice.

Performance Management: Quo Vadis?, Filip Lievens, Philipp Schapers, Christoph N. Herde

Research Collection Lee Kong Chian School Of Business

Traditionally performance management has been described as a powerful tool in Human Resource Management (HRM) because it has potentially a wide array of application possibilities for various HR topics. However, the reality in practice is different. Various surveys reported that more than 90 percent of the performance management systems are unsuccessful. Further studies have shown that up to 75% of staff feel that their organization’s performance management system does not help them to improve their performance and is largely a waste of time (e.g., Capelli & Tavis, 2016; Pulakos, 2009). Economic analyses of the return on investment (as compared to …

Privacy At Work: A Review And A Research Agenda For A Contested Terrain, Devasheesh P. Bhave, Laurel H. Teo, Reeshad S. Dalal

Research Collection Lee Kong Chian School Of Business

Privacy in the workplace is a pivotal concern for employees and employers. Employees expect to be in control of the personal information and access they provide to the organization. Employers, however, expect extensive information regarding their employees as well as extensive access to employees’ presence. The chasm between these two often competing expectations has been magnified by regulatory and technological trends. We begin the review by integrating viewpoints from multiple disciplines to disentangle definitions of privacy and to delineate the privacy contexts of information privacy and work environment privacy. We then identify the key stakeholders of privacy in the workplace …

Within-Person Job Performance Variability Over Short Timeframes: Theory, Empirical Research, And Practice, Reeshad S. Dalal, Balca Alaybek, Filip Lievens

Research Collection Lee Kong Chian School Of Business

We begin by charting the evolution of the dominant perspective on job performance from one that viewed performance as static to one that viewed it as dynamic over long timeframes (e.g., months, years, decades) to one that views it as dynamic over not just long but also short timeframes (e.g., minutes, hours, days, weeks)—and that accordingly emphasizes the within-person level of analysis. The remainder of the article is devoted to the newer, short-timeframe research on within-person variability in job performance. We emphasize personality states and affective states as motivational antecedents. We provide accessible reviews of relevant theories and highlight the …

Political Ideology Of The Board And Ceo Dismissal Following Financial Misconduct, Uisung Park, Warren Boeker, David Gomulya

Research Collection Lee Kong Chian School Of Business

Why do some boards refuse to take serious action against CEOs who have committed financial misconduct? Past work has directed attention to the antecedents of misconduct while largely overlooking this question. The relatively few studies to examine it have typically revolved around the capacity of boards to take action, or their relationships to their CEOs. This study instead examines how the beliefs and values held by board members can influence their actions following financial misconduct. Focusing on political ideology, we argue and find that politically conservative boards are more likely to respond by dismissing the CEO than are liberal boards. …

Status Reports Of The Fisheries And Aquatic Resources Of Western Australia 2018/19. State Of The Fisheries, Daniel J. Gaughan, K. Santoro

Status Reports of the Fisheries and Aquatic Resources

The Status Reports of the Fisheries and Aquatic Resources of Western Australia (SRFAR) provide an annual update on the state of the fish stocks and other aquatic resources of Western Australia (WA). These reports outline the most recent assessments of the cumulative risk status for each of the aquatic resources (assets) within WA’s six Bioregions using an Ecosystem Based Fisheries Management (EBFM) approach.

Detection Of Low-Level Egfr C.2369 C>T (P.Thr790met) Resistance Mutation In Pre-Treatment Non-Small Cell Lung Carcinomas Harboring Activating Egfr Mutations And Correlation With Clinical Outcomes, Linda Ye, Nima Mesbah Ardakani, Carla Thomas, Katrina Spilsbury, Connull Leslie, Benhur Amanuel, Michael Millward

IHR Papers and Journal Articles

Increasing evidence points to the presence of low-level de novo T790M mutations in patients with non-small cell lung carcinoma (NSCLC) harboring activating EGFR mutations. We utilized digital PCR (dPCR), a highly sensitive gene mutation detection method, to detect pre-treatment T790M mutations in NSCLC tumor samples and correlated the T790M status with clinical features and patient outcomes. DNA extracted from pre-treatment NSCLC tumor tissue with known activating EGFR mutations, diagnosed between October 2010 and May 2017 at PathWest laboratory, was used to perform targeted dPCR for quantitative detection of T790M mutations. T790M was detected in 42 of 109 pre-treatment samples (38.5%). …

Defining The Border Of The Subthalamic Nucleus For Deep Brain Stimulation: A Proposed Model Using The Symmetrical Sigmoid Curve Function, Anthony M.T Chau, Angela Jacques, Christopher R. Lind

IHR Papers and Journal Articles

Background: The subthalamic nucleus (STN) is an important target during deep brain stimulation (DBS). Accurate lead placement is integral to achieving satisfactory clinical outcomes; however, the STN remains a structure whose visualization is highly variable with borders often difficult to define. We aimed to develop an objective method of evaluating the visibility of the STN on preoperative magnetic resonance imaging (MRI) to standardize future comparative assessments between imaging protocols and patient-specific parameters.

Methods: An imaging study of 64 prospectively collected patients undergoing bilateral DBS of the STN for various movement disorders was performed with institutional approval. MRI scans were acquired …

Do Peers Increase Older Adults' Participation In Strength Training? Pilot Randomized Trial, Elissa Burton, Karen Levit, Jim Codde, Keith D. Hill, Anne-Marie Hill

IHR Papers and Journal Articles

Fewer than 20% of older adults participate in strength training (ST). Barriers to ST participation include not knowing where to go or not having someone to go with. To address these barriers, the authors provided older adults with a peer (older person already participating in ST) to support their engagement. The aim of this pilot randomized controlled trial was to determine whether older adults who were provided with a peer when participating in ST were more likely to be participating in ST 4 weeks postintervention, compared with those receiving ST alone. Fifty-one ST participants were recruited; 40 completed the intervention …

Fatherhood Too Soon. Anxiety, Depression And Quality Of Life In Fathers Of Preterm And Term Babies: A Longitudinal Study, Ingrid Beatrice Petersen, Julie Anne Quinlivan

IHR Papers and Journal Articles

Introduction: Fathers are increasingly recognized as playing a critical role in the family unit and emotional development of children. The birth of a preterm baby can be confronting, yet there is limited research that explores how preterm birth might impact on father’s emotional wellbeing and quality of life. The aim of the study was to monitor quality of life and psychological wellbeing in a group of fathers to explore if a preterm birth altered outcomes in these two domains.

Methods: Institutional ethics committee approval was obtained. Australian men (N = 1000) were recruited in the antenatal period via their …

Paediatric Nurses' Satisfaction With Organisational Communication, Job Satisfaction, And Intention To Stay: A Structural Equation Modelling Analysis, Gemma Doleman, Di Twigg, Sara Bayes, Paola T. Chivers

IHR Papers and Journal Articles

Aims: To examine the effect of paediatric nurses’ organisational communication satisfaction on job satisfaction and intention to stay in their role.

Background: Nurses’ satisfaction with organisational communication has not been studied in-depth in recent years and specifically, there is a paucity of evidence in relation to paediatric nurses’ job satisfaction and intention to stay in their current job.

Methods: A cross-sectional quantitative research design using questionnaires was used. Descriptive statistics were used to analyse demographic data and structural equation modelling was used to analyse the hypothesised models.

Findings: The constructs of supervisor relationships, communication climate and media quality had a …

Sharing A Place-Based Indigenous Methodology And Learnings, Sandra Wooltorton, Len Collard, Pierre Horwitz, Anne Poelina, David Palmer

Nulungu Journal Articles

Building on a methodology of Cooperative Inquiry, the outcomes of five interconnected place-based learning projects from Australia are synthesised and elaborated in this paper. The methodology can facilitate the everyday living and sharing of an Earth-based consciousness: one that enriches Transformative Sustainability Education (TSE) through recognising meanings and stories in landscape, and celebrates Indigenous ways of knowing, being and doing. Indigenous-led environmental education is shown to link with one of the longest continuous environmental education systems in the world and it is contended that because of its ongoing history, environmental education carries a cultural obligation. In Australia, every landscape is …

Mesothelial Cells Regulate Immune Responses In Health And Disease: Role For Immunotherapy In Malignant Mesothelioma, Steven E. Mutsaers, Fiona J. Pixley, Cecilia M. PrêLe, Gerard F. Hoyne

Health Sciences Papers and Journal Articles

Highlights:

• Mesothelial and immune cell interactions play a crucial role in tissue homeostasis in the serosal cavities such as the pleura.

• Mesothelin is viewed as an attractive target for solid tumors, including malignant mesothelioma.

• Checkpoint inhibitor therapy has shown variable efficacy against malignant mesothelioma.

• CAR T cell therapies are being evaluated for malignant mesothelioma.

• Treatment of malignant mesothelioma will require multimodality approaches with immunotherapy central to future therapeutic approaches.

The mesothelium when first described was thought to function purely as a non-adhesive surface to facilitate intracoelomic movement of organs. However, the mesothelium is now recognized as a dynamic cellular membrane …

Physical And Energy Demand Of Soccer: A Brief Review, Filippo Dolci, Nicolas H. Hart, Andrew E. Kilding, Paola Chivers, Benjamin Piggott, Tania Spiteri

Health Sciences Papers and Journal Articles

Soccer is a complex and exhaustive team-sport requiring a high level of tactical, technical, and physical ability to succeed. During a competitive match, a random combination of explosive and powerful activities, together with technical and tactical gestures, is performed in an intermittent manner over a 90-minute game. This review presents a detailed analysis and up-to-date synthesis of the literature describing activities and energy system contribution during soccer to provide to strength and conditioning coaches a clear understanding of soccer players’ physical needs during competition.

Clinically Significant Depressive Symptoms Are Prevalent In People With Extremely Short Prognoses - A Systematic Review, Wei Lee, Marley Pulbrook, Caitlin Sheehan, Slavica Kochovska, Sungwon Chang, Annmarie Hosie, Elizabeth Lobb, Deborah Parker, Brian Draper, Meera R. Agar, David Currow

Nursing Papers and Journal Articles

Context: Currently, systematic evidence of prevalence of clinically significant depressive symptoms in people with extremely short prognoses is not available to inform its global burden, assessment, and management.

Objectives: To determine the prevalence of clinically significant depressive symptoms in people with advanced life-limiting illnesses and extremely short prognoses (range of days to weeks).

Methods: A systematic review and meta-analysis (random effects model) were performed (PROSPERO: CRD42019125119). MEDLINE, Embase, PsycINFO, CINAHL, and CareSearch were searched for studies (1994-2019). Data were screened for prevalence of clinically significant depressive symptoms (assessed using validated depression-specific screening tools or diagnostic criteria) of adults with advanced …

Fiscal Policy Transmission Mechanism In Pakistan: A General Equilibrium Analysis, Muhammad Raashid, Abdul Saboor, Shahzad Ahmad

Business Review

This paper explores the impact of fiscal spending on key macroeconomic indicators for Pakistan economy using an estimated open economy new Keynesian dynamic stochastic general equilibrium (DSGE) model. Results show that a positive shock to government consumption leads to fall in private consumption, private investment and exports owing to negative wealth effect, rise in interest rate and domestic currency appreciation, respectively. Imports and inflation also rise. Estimated values of present value fiscal multipliers are 0.54, 0.29 and 0.18 after 1 year, 5 years and 10 years, respectively. These results show that although positive in the short run, yet the magnitude …

High School Competitive Diving Injuries: National Athletic Treatment Injury And Outcomes Network (Nation), Susan M. Braid, Eric Schussler

Ellmer School of Nursing Faculty Publications

Purpose: Elite diving coaches and USA diving officials have become increasingly concerned about injury prevention among adolescent divers. However, little is known about such injuries. The purpose of this study was to describe the injuries among high school students who participated on high school diving teams.

Subjects: High school students who participated on the diving teams of high schools that were included in the National Athletic Treatment, Injury and Outcomes Network (NATION) for 2011–2014.

Methods: Descriptive epidemiology using injury exposure data on 56 boys' Swimming and Diving teams and 55 girls' Swimming and Diving teams from the National Athletic Treatment, …

Using Social Media As A Platform For Increasing Knowledge Of Lung Cancer Screening In High-Risk Patients, Aimee Strong, Michelle Renaud

Ellmer School of Nursing Faculty Publications

Background: Uptake in lung cancer screening for high-risk patients remains low. Eligible patients may not know that this preventive service is available and covered by insurance.

Objectives: The objective of this study was to explore using social media to educate patients about lung cancer screening and assess motivation to discuss lung cancer screening with health-care providers after viewing the educational program. Methods: Subjects ages 55 to 77 who were current smokers or former smokers who quit in the past 15 years with a more than 30-pack-year smoking history were recruited via a Facebook advertisement. Subjects completed a demographic survey and …