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Estrogen Regulation Of Mir-9-5p And Mir-9-3p Stability And Localization In The Aging Female Brain, Chun Kim

Dissertations

In females, levels of estrogens fluctuate across the lifespan and rapidly decline during menopause. Hormone replacement therapy (HRT) has been introduced as a clinical alternative to replenish systemic levels of 17β-estradiol (E2), the primary estrogen in circulation. However, studies from the Women's Health Initiative revealed a critical period immediately following the onset of menopause where HRT is efficacious. Here, we identified the differential regulation of miRNAs, small non-coding RNAs that inhibit translation, as a potential mechanism for this temporal switch in estrogen action. Specifically, early - but not late - E2 administration following ovariectomy in a rat model of menopause …

Determining The Genetic And Phenotypic Profile Of Cord Blood Derived T Regulatory Cells And The Effect Of Calcitriol On Immune Suppression, Anya Nikolai-Yogerst

Dissertations

Recent outbreaks in vertically transmitted viruses, such as Zika virus and HIV, have rejuvenated interest in fetal and neonatal immune tolerance. Babies are susceptible to vertically transmitted viruses because fetal and neonatal immune systems are considered to be immune-privileged and will tolerate antigens presented to them by their mother. Thus, understanding the mechanisms of this tolerance is important to design effective treatments for infected mothers to protect their offspring. Here, I define a novel Treg, a type of T cell that mediates tolerance, named bidirectional T cells (BiT), found in human umbilical cord blood (UCB). These cells are induced by …

Factors Associated With Diabetic Peripheral Neuropathy And Quality Of Life Among Type 2 Diabetes Patients In Saudi Arabia, Awatef Ibraheem

Dissertations

Evidence has suggested that diabetic peripheral neuropathy (DPN) is associated with decreased quality of life (QoL) and impaired physical and emotional health. About 82% of the diabetic population in Saudi Arabia show signs of DPN. However, it is under-recognized and undertreated. Further, DPN is linked to several clinical and metabolic risk factors. However, there is minimal evidence from Saudi Arabia on the impact of DPN on the individual's QoL. The aims of this current study were to (1) examine the impact of DPN symptoms on functioning, health perception, and QoL and (2) explore the biologic and individual factors associated with …

Victims Of Child Sex Trafficking: Are U.S. Pediatricians Ready To Identify, Assess, Treat And Protect Them?, Bidisha Sinha

Dissertations

The trafficking of children for commercial sexual exploitation is a gross violation of human rights and a global, public health issue that is rapidly growing and prevalent. Due to the clandestine nature of this crime and the general lack of public knowledge about it, identifying and protecting victims of child sex trafficking (CST) is fraught with challenges. Therefore, it is imperative that healthcare professionals - often the only professionals with whom CST victims come in contact while in captivity - are properly educated and trained on this topic. A literature review reveals there is little knowledge about pediatricians' education and …

Modernism's Legacies: Forms, Feelings, And Figures, Shelby Sleevi

Dissertations

My dissertation, entitled "Modernism's Legacies: Forms, Feelings, and Figures," explores American modernism's legacies within contemporary fiction, not only as a set of aesthetic trends but also as a looming and influential mythos. Whether the practices and concerns of early twentieth-century literary modernism are evoked through obvious allusion, explicit reference, or strong resonance on the level of narrative, the contemporary texts in my discussion together attest to modernism's continued influence on and relevance for our current era. Tracing the legacies of William Faulkner, Gertrude Stein, Djuna Barnes, and Vladimir Nabokov in the contemporary fictions of Edward P. Jones, Julie Otsuka, George …

The Flexible Impact Of Affective States On Group Decision-Making And Ideational Creativity, Young-Jae Yoon

Dissertations

Positive and negative affect are often thought to influence the cognitive performance of individuals and groups via their effects on two different dimensions of cognitive processing style: heuristic vs. systematic processing, and global vs. local attentional focus. Recently, research has suggested that the effects of affective states on the analytic and creative performance of individuals depend on the relative dominance of heuristic vs. systematic processing (for analytic performance) and of a global vs. local attentional focus (for creative performance) just prior to the affect's arousal (Huntsinger, Isbell, & Clore, 2014; Huntsinger & Ray, 2016). Extending this individual-level evidence to small …

Postconviction Innocence Review In The Age Of Progressive Prosecution, Elizabeth H. Webster

Criminal Justice & Criminology: Faculty Publications & Other Works

The Article examines how prosecutors adopt legal standards, how they evaluate both forensic and non-forensic new evidence of innocence, and how and when they acknowledge innocence—all in the context of the highly discretionary postconviction arena.

The Role Of Rewards Leaders In Corporate Social Responsibility And Sustainability, Dow Scott, Ewa Beck-Krala, Katarzyna Klmkewicz

School of Business: Faculty Publications and Other Works

No abstract provided.

Findings From Two Decades Of Total Rewards Research: What Worldatwork Members Have Taught Us, Tom Mcmullen, Dow Scott

School of Business: Faculty Publications and Other Works

No abstract provided.

Fiona J. Griffiths, Nuns’ Priests’ Tales: Men And Salvation In Medieval Women’S Religious Life, Tanya Stabler Miller

History: Faculty Publications and Other Works

This work is a review of the book Nuns’ Priests’ Tales: Men and Salvation in Medieval Women’s Religious Life, written by Fiona J. Griffiths.

Climate Change And Global Security, Nathan Jones, John P. Sullivan

Journal of Strategic Security

No abstract provided.

Climate Change And Hybrid Warfare Strategies, Chad M. Briggs

Journal of Strategic Security

Concepts of hybrid warfare and climate security are contested on their own, and are rarely considered as connected in planning for future security risks. Yet climate change presents new hazards for national security, and opportunities for those looking to foment instability and uncertainty in traditional institutions. This article examines the connections between climate change risks and hybrid war strategies, and focuses on concepts of resilience targeting, information warfare, and geoengineering, illustrating that ‘full spectrum’ analyses of security are necessary in developing future security strategies.

Climate Change, Environmental Terrorism, Eco-Terrorism And Emerging Threats, Paola Andrea Spadaro

Journal of Strategic Security

The footprint of human advancement has accelerated a climate variability with no precedents, further driving devastating natural and social events. The decrease in basic resources like water, has already been identified as a driver of violent conflicts, which have given way to the strengthening of terrorist organizations that used the environment as a tool of coercion. The damage caused to the earth’s ecosystem has additionally raised a wave of defensive activism that was initially considered as eco-terrorism. While the original eco-movements had not induced fatalities, recent extremist organizations are showing a more violent anti-progress and pro-environment agenda. Added to these, …

Climate Change, Water Scarcity, And The Potential For Interstate Conflict In South Asia, Michael T. Klare

Journal of Strategic Security

Ever since American security analysts began to consider the impact of global warming on international security, water has been viewed as an especially critical factor. In many parts of the developing world, water supplies are already insufficient to meet societal requirements, and, by shrinking these supplies further, climate change will cause widespread hardship, unrest, and conflict. But exactly what role water plays in this equation has been the subject of considerable reassessment over time. When analysts first examined warming’s impacts, they largely assumed that climate-related water scarcities would most likely provoke conflict within nations; only later did analysts look closely …

Environmental Crime In Transnational Context: Global Issues In Green Criminology. By Toine Spapens, Rob White, & Wim Huisman. New York, N.Y.: Routledge, 2016., William Dittmann, Ph.D.

Journal of Strategic Security

No abstract provided.

Between Five Eyes: 50 Years Of Intelligence Sharing By Anthony R. Wells. Havertown, Pa: Casemate Publishers. 2020., Mark T. Peters Ii

Journal of Strategic Security

No abstract provided.

Notes From The Field: Culturally Adapted Research Methods For South Asian Participants, Erum Agha, Abha Rai

Social Work: School of Social Work Faculty Publications and Other Works

South Asian immigrants form one of the largest immigrant groups in the United States. However, they remain understudied despite their large presence in the country. They are often lumped with other Asians or classified under the category "other" in national studies, which leads to a limited knowledge about this group. To address this methodological challenge, a representative multi-site sample of South Asian participants must be recruited to participate in research studies so their unique issues can be studied appropriately. This paper discusses best practices and culturally responsive ways of conducting ethical research with this unique population and delineates specific recruitment, …

Your Goals And You - Don’T Let Your Goals Get (To) You …. Before You Can Get To Them!, Shweta Singh

Social Work: School of Social Work Faculty Publications and Other Works

What is the one thing you can count on as far as goals are concerned? Not one thing but many things and secondly- your goals are similar to goals of many people around the world, who (interestingly enough) have really nothing in common with you. And finally- that is because how we decide our goals, has very little to do with what is inside us and more about the surrounding influences.

Just lean back and think about how much you are taught and selectively exposed to - by way of opinions, ideas, thoughts about what an ideal life is? Who …

Narrative Readings Of The Religious Authorities In John: A Response To Urban C. Von Wahlde, Christopher W. Skinner

Theology: Faculty Publications and Other Works

The third fascicle of New Testament Studies in 2017 contained an article by Urban C. von Wahlde in which he critiqued contemporary narrative readings of the religious authorities in the Fourth Gospel. In this article, I respond to some of his claims by (1) pointing out specific concerns he has overlooked, and (2) providing a counterpoint to some of his broad claims about contemporary narrative-critical readings of the Fourth Gospel.

Sibylline Oracles, Olivia Stewart Lester

Theology: Faculty Publications and Other Works

No abstract provided.

Insights Into Acinetobacter Baumannii: A Review Of Microbiological, Virulence, And Resistance Traits In A Threatening Nosocomial Pathogen, Carole Ayoub Moubareck, Dalal Hammoudi Halat

All Works

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Being a multidrug-resistant and an invasive pathogen, Acinetobacter baumannii is one of the major causes of nosocomial infections in the current healthcare system. It has been recognized as an agent of pneumonia, septicemia, meningitis, urinary tract and wound infections, and is associated with high mortality. Pathogenesis in A. baumannii infections is an outcome of multiple virulence factors, including porins, capsules, and cell wall lipopolysaccharide, enzymes, biofilm production, motility, and iron-acquisition systems, among others. Such virulence factors help the organism to resist stressful environmental conditions and enable development of severe infections. Parallel …

Kasus Ujaran Kebencian Dalam Berita Surat Kabar Di Hindia Belanda, Fajar Muhammad Nugraha, Reynaldo De Archellie, Cresentia Carra Nethania Clement

Paradigma: Jurnal Kajian Budaya

This article is a preliminary study that explores past events of the Dutch East Indies colonial government, specifically describing criminal cases of hate speech or haatzaai depicted in newspaper news between 1879 and 1942. The Dutch East Indies colonial government controlled freedom of thought, expression, and politics of the native population by using the legal instruments Wetboek van Strafrecht voor Nederlandsch Indie, especially articles 154, 155, 156, and 157. These four articles are known as haatzaai artikelen. This regulation was published and enforced in the Dutch East Indies in 1918. This article uses twenty-eight newspaper news articles published in ten …

House Rules: Why Implementing Express Rules Governing Conflicts Of Law Absent Parties Explicit Choice Will Strengthen International Arbitration Tribunals, Saikrishna Srikanth

Journal of Business & Technology Law

No abstract provided.

The Value Of Title Insurance, Tom Hayden, Jordan Kelner

Journal of Business & Technology Law

No abstract provided.

Jesner V. Arab Bank, Plc: Limiting The Liability Of Foreign Corporations By Curbing The Breadth Of The Alien Tort Statute, Sudipta Das

Journal of Business & Technology Law

No abstract provided.

Affordances And Constraints: Pre-Service Science Educators Co-Teaching In Support Of Ells, Steven Drouin, Katya Aguilar, Virginia Lehmkuhl-Dakhwe

Faculty Publications

Co-teaching has increasingly been utilized as an alternative model for the student teaching experience in pre-service education. Recent literature highlights potential for co-teachers to develop by engaging in cycles of inquiry in learning communities. The purpose of this study was to explore the experience of a science student teacher who engaged in cycles of inquiry around supporting English language learners (ELLs) in a co-teaching student teaching placement. This qualitative case study involved a science mentor teacher and a science student teacher engaged in a yearlong co-teaching placement. Data sources included surveys, interviews, and written and oral lesson plans and reflections. …

Fragmented Spectatorship And Artistic Beholding In The Red Badge Of Courage, John Kerkering

English: Faculty Publications and Other Works

No abstract provided.

Fair Housing Enforcement In The Age Of Digital Advertising: A Closer Look At Facebook’S Marketing Algorithms, Nadiyah J. Humber, James Matthews

Law Faculty Scholarship

No abstract provided.

In West Philadelphia Born And Raised Or Moving To Bel-Air? Racial Steering As A Consequence Of Using Race Data On Real Estate Websites, Nadiyah J. Humber

Law Faculty Scholarship

No abstract provided.

Focus On The Future: An Interview With Michaela Bland, Esq., Nicole P. Dyszlewski

Law Faculty Scholarship

No abstract provided.