Digital Commons Network^™

A Narrative Case Study Of Transfer Students In Instrumental Music Education, Ashley Glenn

Dissertations

Transfer students in music fields face challenges that are different from other fields of study. Research has shown that transfer students in music are expected to acclimate and operate as upperclassmen with minimal onboarding while also potentially having to retake courses they received credit for at the community college level. This study examines the experiences of five transfer students in music education through the lens of Schlossberg’s transition theory and Dewey’s model of transaction. Building on existing transfer student research, it asks: what do transfer students experience in terms of acceptance and self-integration, and how do these experiences affect transfer …

A 3d Image-Guided System To Improve Myocardial Revascularization Decision-Making For Patients With Coronary Artery Disease, Haipeng Tang

Dissertations

OBJECTIVES. Coronary artery disease (CAD) is the most common type of heart disease and kills over 360,000 people a year in the United States. Myocardial revascularization (MR) is a standard interventional treatment for patients with stable CAD. Fluoroscopy angiography is real-time anatomical imaging and routinely used to guide MR by visually estimating the percent stenosis of coronary arteries. However, a lot of patients do not benefit from the anatomical information-guided MR without functional testing. Single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is a widely used functional testing for CAD evaluation but limits to the absence of anatomical information. …

Machine Learning Approaches For Improving Prediction Performance Of Structure-Activity Relationship Models, Gabriel Idakwo

Dissertations

In silico bioactivity prediction studies are designed to complement in vivo and in vitro efforts to assess the activity and properties of small molecules. In silico methods such as Quantitative Structure-Activity/Property Relationship (QSAR) are used to correlate the structure of a molecule to its biological property in drug design and toxicological studies. In this body of work, I started with two in-depth reviews into the application of machine learning based approaches and feature reduction methods to QSAR, and then investigated solutions to three common challenges faced in machine learning based QSAR studies.

First, to improve the prediction accuracy of learning …

Influences Of Conservation Farming Practice Adoption Amongst Vineyards On The Central Coast Of California, Jazlyn Guerrero

Master of Science in Environmental Sciences and Management Projects

Farming practices will require changes to reduce crop sensitivity to climate change, which is projected to cause extreme heat events, variable precipitation, extended periods of drought, and increasing presence of pest and disease. Conservation agricultural practices build farm resiliency to climate impacts by improving soil health, reducing erosion and sediment runoff, and improving water infiltration. Literature on the adoption of conservation agriculture practices find no universal factors that indicate adoption of practices but suggest that the adoption of practices can be better understood by investigating practices specific variables and farm level characteristics and their implications on adoption. Our objective is …

Agricultural Conservation Decision-Making Under Environmental Risk And Uncertainty On The California Central Coast, Diego Rivera

Master of Science in Environmental Sciences and Management Projects

Global climate change is a process that is, in part, caused by agricultural practices, and will adversely affect agricultural operations, especially vineyards. The objective of this project is to determine how viticulturalists in Paso Robles, California view global climate change and how they use conservation practices that combat climate change and prepare for the associated negative effects. Interviews were conducted with vineyard advisors and managers to determine what general risks associated with wine grape production exist for their operations, and whether wine advisors and producers perceive global climate change to be one of those risks. The interview responses were then …

Roles For A Lipid Phosphatase In The Activation Of Its Opposing Lipid Kinase, Bethany S. Strunk, N. Steinfeld, S. Lee, N. Jin, Cecilia Munõz-Rivera, Garrison Meeks, Asha Mary Thomas, C. Akemann, A. K. Mapp, J. A. Macgurn, L. S. Weisman

Biology Faculty Research

Fig4 is a phosphoinositide phosphatase that converts PI3,5P2 to PI3P. Paradoxically, mutation of Fig4 results in lower PI3,5P2, indicating that Fig4 is also required for PI3,5P2 production. Fig4 promotes elevation of PI3,5P2, in part, through stabilization of a protein complex that includes its opposing lipid kinase, Fab1, and the scaffold protein Vac14. Here we show that multiple regions of Fig4 contribute to its roles in the elevation of PI3,5P2: Its catalytic site, an N-terminal disease-related surface, and a C-terminal region. We show that mutation of the Fig4 catalytic site enhances the formation of the Fab1-Vac14-Fig4 complex, and reduces the ability …

Chimera-Like Behavior In A Heterogeneous Kuramoto Model: The Interplay Between Attractive And Repulsive Coupling, Nikita Frolov, Vladimir Maksimenko, Soumen Majhi, Sarbendu Rakshit, Dibakar Ghosh, Alexander Hramov

Journal Articles

Interaction within an ensemble of coupled nonlinear oscillators induces a variety of collective behaviors. One of the most fascinating is a chimera state that manifests the coexistence of spatially distinct populations of coherent and incoherent elements. Understanding of the emergent chimera behavior in controlled experiments or real systems requires a focus on the consideration of heterogeneous network models. In this study, we explore the transitions in a heterogeneous Kuramoto model under the monotonical increase of the coupling strength and specifically find that this system exhibits a frequency-modulated chimera-like pattern during the explosive transition to synchronization. We demonstrate that this specific …

Evaluation Of A Novel Shallow Aggregate Ebb-And-Flood Culture System And Transplant Size Effects On Hydroponic Basil Yield, Samuel Doty, Ryan W. Dickson, Michael Evans

Horticulture Faculty Publications and Presentations

Ornamental bedding plant operations transitioning to leafy greens and herb production must decide whether to invest in new hydroponic equipment or modify existing culture systems for edible crops. In addition, common practices used to increase space-use and production efficiencies during bedding plant production may be modified for hydroponic leafy greens and herbs, such as purchasing large seedlings for transplant. The objective of the first experiment was to evaluate plant growth in a modified and novel shallow aggregate ebb-and-flood (SAEF) system intended for bedding plant growers with an emphasis on comparing yield across four basil (Ocimum basilicum) cultivars grown …

A Unique Type Of Loneliness: Infertility In Nineteenth-Century America, Abigail Butler

Theses and Dissertations from 2020

Many diaries and letters written by nineteenth-century Americans display the aching for parenthood and pain of loss due to miscarriage. Though some women felt joy or relief when they recognized they had miscarried or were not pregnant, infertility negatively affected the everyday lives of many men and women in the nineteenth century. Infertility not only disturbed their personal beliefs of family and their role in society, but could cause marital discord, feeling outcast from society, and could lead to other health problems. Women in slavery faced even more serious consequences that included being sold away from their family and/or receiving …

Comparative Spatial And Behavioral Ecology Of The Prairie Lizard Sceloporus Consobrinus In The Arkansas River Valley, E. A. Free Kashon

Theses and Dissertations from 2020

Habitat-driven differences in reptile life-histories have been observed in many species. Prairie lizards, Sceloporus consobrinus, in the Arkansas River Valley inhabit rocky, forested, and intermediate habitat types that exhibit different thermal resource availabilities and habitat structures. I studied prairie lizard space usage and antipredator responses to examine whether lizards exhibit habitat-driven differences in ecology, and whether these differences are influenced, in part, by individual personality. I utilized radio telemetry to track lizards in each of these habitat types and established estimates of space usage and daily linear movements. I used behavioral approaches to quantify lizard antipredator responses to a simulated …

Effects Of Management Efforts On Fledging Success Of Endangered Interior Least Terns (Sternula Antillarum Athalassos) On The Mcclellan-Kerr Arkansas River Navigation System In Arkansas, Trevor N. Jensen

Theses and Dissertations from 2020

The Interior Least Tern (Sternula antillarum athalassos) is an endangered shorebird that primarily nests in colonies on barren riverine sandbars on many major river systems throughout the central United States. Water resource development projects such as damming and channelization have altered the natural flow regimes of these systems leading to a decrease in sandbar quality and quantity, and as a result this species is dependent on management to ensure their recovery. Managers within Arkansas have been applying a variety of management approaches to improve sandbar nesting habitat and success of this population intermittently since 2002, with increased intensity since 2015. …

The Impacts Of Prescribed Burning And Mechanical Thinning On Insect Communities In The Arkansas Ozarks, Aaron P. Tormanen

Theses and Dissertations from 2020

Insects are important in woodland ecosystems due to their role as pollinators and as prey for bats. My research investigated the relationships between forest management, vegetation, and insects in the Ozark National Forest in Arkansas. I selected 30 stands burned at varying frequencies in the last 12 years. Twelve of these stands were burned and mechanically thinned, 12 were only burned, and 6 were untreated. I deployed blacklight traps and malaise traps in each stand monthly from mid-March to mid- November 2019. Over 42,391 insects were collected, and Lepidoptera was the most abundant order. Insects were dried, weighed, and identified …

2020 Fall - Schedule Of Classes, Office Of The Registrar, East Tennessee State University

Registration Resources

No abstract provided.

Kentucky Warbler (Vol. 96, No. 3), Kentucky Library Research Collections

The Kentucky Warbler

No abstract provided.

Effect Of S100b Deletion On Membrane Properties And Localization Of Ncald And Hpca, Natasha Hesketh

Graduate School of Biomedical Sciences Theses and Dissertations

Calcium signaling is particularly important for neuronal function. Neurons utilize a wide range of calcium-binding proteins. Dysregulation of such proteins is linked to neurodegeneration. Neurocalcin delta (NCALD), hippocalcin (HPCA), and S100B are calcium sensors that are expressed in the hippocampus, a brain region essential to memory and severely damaged in Alzheimer’s disease (AD). Despite the potential importance of these proteins, we do not fully understand the physiological significance of their relationship. Because NCALD and HPCA are known to interact with S100B, we hypothesized that the loss of S100B affects NCALD and HPCA localization, and therefore electrical properties, of hippocampal neurons. …

Clemson Commencement Program, August 2020, Clemson University

Clemson Commencement Programs

No abstract provided.

A Qualitative Investigation Of Andragogy In Adult Bible Classes In Lutheran Church — Missouri Synod Congregations In St. Louis, Peter Luther Jurchen

Dissertations

This qualitative study explored what changes, if any, would occur in Lutheran Church–Missouri Synod (LCMS) Bible classes after pastors participated in training that focused on implementing andragogical teaching methods in their Bible classes. The researcher sought to examine Andragogy in its relationship to adult Christian education, specifically in Sunday adult Bible classes. Also, in order to better understand the impact of andragogy in the specific contexts of the study, the researcher investigated the relationship between andragogical principles and LCMS doctrinal positions. Andragogical principles used in this study were derived, broadly conceived, from Malcomb Knowles’s Six Assumptions and Eight Processes of …

Application Of Lignin (Modified/Unmodified ) To Cement And Observing Effects, Ashique Ur Rahman Akond

Master's Theses

Biomass of various types have been known to be important sources of energy or raw material for products in industries for centuries. Biomass have been proven to be cost effective as sources of suitable chemicals that can enhance many industrial processes. Lignin is one of many very valuable components extractable from biomass. Using lignin, modified or unmodified, can improve the sustainability of manufacturing processes. In this work, lignin was extracted from two different biomass, i.e. coffee chaff and sugarcane bagasse. Coffee chaff is the dried skins of coffee beans, the waste product from the roasting process. Sugarcane bagasse is the …

Water Quality Study Of The Muchea Livestock Truck Wash, Simon Clarendon, David Weaver, Justin L.M Hardy, Claire Coffey, Robert Summers, David Rogers, Peta Richards

Resource management technical reports

Across Australia there is a lack of information on the quality of the water discharged from facilities that are used to wash livestock trucks. This water quality scoping study partially fills that information gap and provides a starting point for future planning, design and construction of livestock truck washes.

The study was undertaken in 2011–12 at the Western Australian Muchea Livestock Centre, and aimed to gain insights into water quality associated with the truck wash facility at that site. These insights can help to inform the planning for further construction of truck wash facilities throughout the state, and whether disposing …

Decoding The Mechanisms Underlying Cell-Fate Decision-Making During Stem Cell Differentiation By Random Circuit Perturbation., Bin Huang, Mingyang Lu, Madeline Galbraith, Herbert Levine, Jose N Onuchic, Dongya Jia

Faculty Research 2020

Stem cells can precisely and robustly undergo cellular differentiation and lineage commitment, referred to as stemness. However, how the gene network underlying stemness regulation reliably specifies cell fates is not well understood. To address this question, we applied a recently developed computational method, random circuit perturbation (RACIPE), to a nine-component gene regulatory network (GRN) governing stemness, from which we identified robust gene states. Among them, four out of the five most probable gene states exhibit gene expression patterns observed in single mouse embryonic cells at 32-cell and 64-cell stages. These gene states can be robustly predicted by …

Plaster Creek Stewards Green Team Initiative, Michael Akpabey, David E. Martinez Vasquez, David P. Warners

Student Papers and Reports

No abstract provided.

Hybrid Cyclic/Linear Peptides In A Multi-Component Lipid Structure As A Sirna Delivery System, Abdulaziz Alasmari

Pharmaceutical Sciences (MS) Theses

Delivering siRNA is challenging due to many obstacles, such as extremely short in vivo half-life, rapid elimination via glomerular filtration, and inability to cross cell membranes due to the hydrophilic and negatively-charged nature. Thus, a delivery system is needed to deliver the siRNA into the cells by crossing the negatively-charged phospholipid cell membrane. The goal of this project was to design hybrid cyclic-linear peptides as siRNA delivery system. We designed and synthesized hybrid cyclic-linear peptides [R5K]W5, [R6K]W6, and [R5K]W7 containing positively-charged arginine residues attached to hydrophobic tryptophan chains for more efficient interaction with siRNA and to improve siRNA internalization into …

Utah State Magazine, Fall 2020, Utah State University

Utah State Magazine

The quarterly magazine for friends and alumni of Utah State University.

A Systematic Review Of Interventions For Family Caregivers Who Care For Patients With Advanced Cancer At Home., Soojung Ahn, Rafael D. Romo, Cathy L. Campbell

Nursing | Faculty Scholarship

OBJECTIVE: To examine the characteristics of interventions to support family caregivers of patients with advanced cancer.

METHODS: Five databases (CINAHL, Medline, PsycINFO, Web of Science, and the Cochrane Library) were searched for English language articles of intervention studies utilizing randomized controlled trials or quasi-experimental designs, reporting caregiver-related outcomes of interventions for family caregivers caring for patients with advanced cancer at home.

RESULTS: A total of 11 studies met the inclusion criteria. Based on these studies, the types of interventions were categorized into psychosocial, educational, or both. The characteristics of interventions varied. Most interventions demonstrated statistically significant results of reducing psychological …

Glucose-Induced, Duration-Dependent Genome-Wide Dna Methylation Changes In Human Endothelial Cells, Erfan Aref-Eshghi, Saumik Biswas, Charlie Chen, Bekim Sadikovic, Subrata Chakrabarti

Paediatrics Publications

DNA methylation, a critical epigenetic mechanism, plays an important role in governing gene expressions during biological processes such as aging, which is well known to be accelerated in hyperglycemia (diabetes). In the present study, we investigated the effects of glucose on whole genome DNA methylation in small [human retinal microvascular endothelial cells (HRECs)] and large [human umbilical vein endothelial cells (HUVECs)] vessel endothelial cell (EC) lines exposed to basal or high glucose-containing media for variable lengths of time. Using the Infinium EPIC array, we obtained 773,133 CpG sites (probes) for analysis. Unsupervised clustering of the top 5% probes identified four …

Persistence Of Diet Effects On The Drosophila Suzukii Microbiota, Yanira Jiménez Padilla, Ebenezer Esan, Kevin D. Floate, Brent J. Sinclair

Biology Publications

The insect commensal microbiota consists of prokaryotes and eukaryotes. The effect of diet and the persistence of the gut microbiota in Drosophila suzukii (Matsumura) (Diptera: Drosophilidae) are not well-understood. We transferred subsets of a single population of D. suzukii to different fruit-based diets (blueberry, raspberry, and strawberry) for three generations and then returned them to a common, banana-based, laboratory diet. We used 16S (bacteria) and ITS (fungi) sequencing of female endosymbiont-free flies to identify the microbiota. We identified 2700 bacterial and 350 fungal OTUs; there was no correlation between the number of bacterial and fungal OTUs in a sample. Bacterial …

Glutamate And Dysconnection In The Salience Network: Neurochemical, Effective Connectivity, And Computational Evidence In Schizophrenia, Roberto Limongi, Peter Jeon, Michael Mackinley, Tushar Das, Kara Dempster, Jean Théberge, Robert Bartha, Dickson Wong, Lena Palaniyappan

Medical Biophysics Publications

Background: Functional dysconnection in schizophrenia is underwritten by a pathophysiology of the glutamate neurotransmission that affects the excitation-inhibition balance in key nodes of the salience network. Physiologically, this manifests as aberrant effective connectivity in intrinsic connections involving inhibitory interneurons. In computational terms, this produces a pathology of evidence accumulation and ensuing inference in the brain. Finally, the pathophysiology and aberrant inference would partially account for the psychopathology of schizophrenia as measured in terms of symptoms and signs. We refer to this formulation as the 3-level hypothesis. Methods: We tested the hypothesis in core nodes of the salience network (the dorsal …

Uses Of Ultrasound In Stroke Prevention, J. David Spence

Department of Medicine Publications

Ultrasound methods are useful in stroke prevention in several ways. Measurement of carotid plaque burden, as either total plaque area (TPA) or total plaque volume (TPV) are strong predictors of cardiovascular risk: much stronger than intima-media thickness, which does not represent true atherosclerosis, but a biologically and genetically distinct phenotype. Measurement of plaque burden is also useful for the study of genetics, and of new risk factors such as toxic products of the intestinal microbiome. Carotid plaque burden is highly correlated with and as predictive of risk as coronary calcium scores, but is less costly and does not require radiation. …

Spatial Diffusion, Richard Morrill, Gary L. Gaile, Grant Ian Thrall

Web Book of Regional Science

This volume is about how we come to have the culture and ideas we have. Most social and economic change is a direct consequence of the diffusion of some idea or phenomenon. Ideas become diffused through society in a regular manner, and because of this regularity their diffusion can often be analyzed and even predicted. The same analytical framework applied to describe and predict the spread of some cultural or human phenomenon, such as political turmoil, can also be applied to an analysis of the spread of disease. The authors chronicle the evolution of ideas for analyzing, simulating, and forecasting …

Sex-Specific Modulation Of Blood Pressure And The Renin-Angiotensin System By Ace (Angiotensin-Converting Enzyme) 2, Hong Ji, Aline M. De Souza, Bilkish Bajaj, Wei Zheng, Xie Wu, Robert C. Speth, Kathryn Sandberg

HPD Articles

We showed ACE (angiotensin-converting enzyme) 2 is higher in the kidney of male compared with female mice. To further investigate this sex difference, we examined the role of ACE2 in Ang-[1-8] (angiotensin [1-8])-induced hypertension and regulation of the renin-angiotensin system in the kidney of WT (wild type) and Ace2 KO (knockout) mice. Mean arterial pressure rose faster in WT male than WT female mice after Ang-[1-8] infusion. This sex difference was attenuated in ACE2 KO mice. Ang-[1-8] infusion reduced glomerular AT1R (angiotensin type 1 receptor) binding in WT female mice by 30%, and deletion of abolished this effect. In contrast, …