Digital Commons Network^™

Thyme Awarded Esteemed Klingenstein-Simons Fellowship In Neuroscience, Mary Ashley Canevaro

Browse All News

No abstract provided.

Integrated Framework Of The Immune-Defense Transcriptional Signatures In The Arabidopsis Shoot Apical Meristem, Muhammad Naseem, Özge Osmanoğlu, Martin Kaltdorf, Afnan Ali M.A. Alblooshi, Jibran Iqbal, Fares M. Howari, Mugdha Srivastava, Thomas Dandekar

All Works

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. The growing tips of plants grow sterile; therefore, disease-free plants can be generated from them. How plants safeguard growing apices from pathogen infection is still a mystery. The shoot apical meristem (SAM) is one of the three stem cells niches that give rise to the above ground plant organs. This is very well explored; however, how signaling networks orchestrate immune responses against pathogen infections in the SAM remains unclear. To reconstruct a transcriptional framework of the differentially expressed genes (DEGs) pertaining to various SAM cellular populations, we acquired large-scale transcriptome datasets …

Commencement 2020 (Program, Video And Messages From The Virtual Ceremony), Illinois Wesleyan University

Commencement Ceremonies

Planning for the 2020 Commencement ceremony was a dynamic process due to the COVID-19 pandemic. Several links below contain the messages distributed to students and their families in the months leading up to the event which ultimately took place online on August 2, 2020.

This event also celebrated the students who earned scholastic and activity honors during the 2019-20 academic year by distributing the Honors Day Convocation program.

Effects Of Phosphate Fertilizer On Regrowth Of Medicago Sativa After Defoliation, Huixin Jiang, Yixin Shen, Guiyu Zhai

IGC Proceedings (1977-2023)

No abstract provided.

Caucasian Clover (Trifolium Ambiguum) Is Persistent In New Zealand Montane, Improved Rangeland But Requires Regular Sulphur Application For Productivity, P. Jarvis, R. J. Lucas, J. R. Sedcole

IGC Proceedings (1977-2023)

No abstract provided.

Effects Of Cultivation Of Puccinellia Tenuiflora On The Chemical And Physical Characteristics Of Alkalinized Soil In Western Areas Of Jilin, N. Ishikawa, M. Kato, K. Shimizu, M. Amari, W. Cao, X. Yu, A. Xu

IGC Proceedings (1977-2023)

No abstract provided.

Yield Trends And Soil Mineral Changes In Three Summer Winter Forage Cropping Systems For 5 Consecutive Years In Southern Kyushu, Japan, Sachiko Idota, Yasuyuki Ishii

IGC Proceedings (1977-2023)

No abstract provided.

Correction Of Sulphur Deficiency On Naturalized Pastures Of Western Patagonia (Chile), Christian Hepp

IGC Proceedings (1977-2023)

No abstract provided.

Root Development Of Three Commercial Forage Pigeon‐Pea Cultivars In Artificially Compacted Soil, Rodolfo Godoy, Osny Oliveira Santos Bacchi, Patrícia Menezes Santos, Fernando De Almeida Moreira

IGC Proceedings (1977-2023)

No abstract provided.

Selection Of Forage Pigeon‐Pea (Cajanus Cajan (L.) Millsp) Lines For Soil Decompaction, Rodolfo Godoy, Osny Oliveira Santos Bacchi, Patrícia Menezes Santos, Fernando De Almeida Moreira

IGC Proceedings (1977-2023)

No abstract provided.

The History Of Early Modern Medicine In New Spain, El Primero Sueño, And Poet Sor Juana Inés De La Cruz, Daniel Hughes

Grand Valley Journal of History

This essay analyzes poetry and other writing by Sor Juana Inés de la Cruz in the context of themes from Greco-Roman antiquity and the historical development of medicine in seventeenth century New Spain, now Mexico. Sor Juana’s El Primero Sueño, a Spanish language poetic silva, exhibits copious references to writers from classical antiquity, including Aristotle and Ovid. Establishing a context steeped in ideas from Greco-Roman antiquity, Sor Juana invokes the medical and philosophical legacy of foundational physician Galen of Pergamon. She also expands upon his ideas into the human anatomical realm, reflecting the increased early modern prominence of …

Simulation And Analysis Of The Carrying Capacity For Road Networks Using A Grid-Based Approach, Junqing Shi, Linwu Chen, Fengxiang Qiao, Lei Yu, Qing Li, Guilian Fan

Faculty Publications

The number of vehicles that a road network can carry is limited. When the limit is exceeded, the network system is not able to function effectively. In this paper, an updated cellular automaton model for grid networks with all-way stop-controlled intersections is proposed to simulate the network level critical density and carrying capacity under different conditions, which essentially indicates the limit number of vehicles that the network can handle before going into gridlock. In the proposed model, two update rules, including lane-changing and the longitudinal location update, are adopted to describe the vehicle's movements on road segments according to the …

Genetic Variants And Functional Pathways Associated With Resilience To Alzheimer's Disease., Logan Dumitrescu, Emily R Mahoney, Shubhabrata Mukherjee, Michael L Lee, William S Bush, Corinne D Engelman, Qiongshi Lu, David W Fardo, Emily H Trittschuh, Jesse Mez, Catherine Kaczorowski, Hector Hernandez Saucedo, Keith F Widaman, Rachel Buckley, Michael Properzi, Elizabeth Mormino, Hyun-Sik Yang, Tessa Harrison, Trey Hedden, Kwangsik Nho, Shea J Andrews, Doug Tommet, Niran Hadad, R Elizabeth Sanders, Douglas M Ruderfer, Katherine A Gifford, Annah M Moore, Francis Cambronero, Xiaoyuan Zhong, Neha S Raghavan, Badri Vardarajan, Margaret A Pericak-Vance, Lindsay A Farrer, Li-San Wang, Carlos Cruchaga, Gerard Schellenberg, Nancy J Cox, Jonathan L Haines, C Dirk Keene, Andrew J Saykin, Eric B Larson, Reisa A Sperling, Richard Mayeux, David A Bennett, Julie A Schneider, Paul K Crane, Angela L Jefferson, Timothy J Hohman

Faculty Research 2020

Approximately 30% of older adults exhibit the neuropathological features of Alzheimer's disease without signs of cognitive impairment. Yet, little is known about the genetic factors that allow these potentially resilient individuals to remain cognitively unimpaired in the face of substantial neuropathology. We performed a large, genome-wide association study (GWAS) of two previously validated metrics of cognitive resilience quantified using a latent variable modelling approach and representing better-than-predicted cognitive performance for a given level of neuropathology. Data were harmonized across 5108 participants from a clinical trial of Alzheimer's disease and three longitudinal cohort studies of cognitive ageing. All analyses were run …

Howard Hughes Medical Institute Grant Program Evaluation 2019-2020, Government Research Bureau

Inclusive Science Initiative Program

No abstract provided.

Towards Green Economy: Green Bonds, U. Berdiyev

International Finance and Accounting

The article aims to shed light on a recent financial innovation tool – green bonds on the way to less carbon economy, in which expectations, impacts and preferences versus other traditional types of bonds resulting from green bonds are attempted to reveal. Having learned many cases of green bond issues, especially in Asian and African countries, we can support the view that these bonds can potentially play a key role in greening the economy without penalizing financially the issuers.

Through The Lens Of Latinas: The Influences Of An Out-Of-School Time Stem Program, Chaoyi Wang

Theses & Dissertations

Science, Technology, Engineering, and Mathematics (STEM) have been the foundation for discovery and technological innovation in the United States. The United States considers STEM education as a national priority to compete in the global economy and protect the nation’s innovation ecosystem. The high demand for careers in STEM fields promotes the importance of STEM education. However, Latinos, as the fastest-growing ethnic group in the United States, face many challenges in STEM education relating to a lack of progress, degree attainment, and participation in STEM professions.

This research aimed to explore the learning experience in an out-of-school (OST) STEM program, called …

Heartland Virus In Lone Star Ticks, Alabama, Usa, Brent C. Newman, William B. Sutton, Abelardo C. Moncayo, Holly R. Hughes, Ali Taheri, Thomas C. Moore, Callie J. Schweitzer, Yong Wang

Agricultural and Environmental Sciences Faculty Research

We detected Heartland virus (HRTV) in lone star nymphs collected in 2018 in northern Alabama, USA. Real-time reverse transcription PCR selective for the small segment of the HRTV genome and confirmatory sequencing of positive samples showed high identity with HRTV strains sequenced from Tennessee and Missouri.

Organic Fertilizer Abrasive Grits Increase Soil Available Nitrogen, Plant Height, And Biomass, Michael Carlson, Frank Forcella, Sam Wortman, David Clay, Sharon A. Clay

Agronomy, Horticulture and Plant Science Faculty Publications

In organic cropping systems, air‐propelled abrasive grits can be used to control in‐row weeds. If the applied abrasive grit is an approved organic fertilizer, these applications may serve a dual purpose of weed control and crop fertility. Laboratory soil incubations examined the N mineralization rates of several grit types with differing C/N ratios (Agra Grit [crushed walnut shells, 170:1], corncob grit [91:1], Sustane [composted turkey litter, 5.0:1], Phytaboost Plant Food [crushed and pelletized soybean meal, 5.0:1]). A greenhouse study determined plant wheat (Triticum aestivum L.), kale (Brassica napus pabluaria DC), and velvetleaf (Abutilon theophrasti Medik.) growth response …

Porcine Cytokines, Chemokines And Growth Factors: 2019 Update, Harry D. Dawson, Yongming Sang, Joan K. Lunney

Agricultural and Environmental Sciences Faculty Research

Pigs are a major food source worldwide as well as major biomedical models for human physiology and therapeutics. A thorough understanding of porcine immunity is essential to prevent and treat infectious diseases, and develop effective vaccines and therapeutics. The use of pigs as biomedical models is dependent on the growing molecular and immune toolbox. This paper summarizes current knowledge of swine cytokines, chemokines and growth factors, identifying 289 pig proteins, characterizing knowledge of their gene structures and families. It identifies areas in the current swine genome build that need to be clarified. A broad-based literature and vendor search was conducted …

Physical Activity, Sedentary Behavior, And Sleep Quality In Adults With Primary Hypertension And Obesity Before And After An Aerobic Exercise Program: Exerdiet-Hta Study, Aitor Martinez Aguirre-Betolaza, Iñigo Mujika, Paul Loprinzi, Pablo Corres, Ilargi Gorostegi-Anduaga, Sara Maldonado-Martín

Faculty and Student Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Background: The purposes of the study were to: analyze, by objective (accelerometry) and subjective (International Physical Activity Questionnaire, IPAQ) methodologies, the physical activity (PA) and sedentary behavior (SB) in healthy adults (HEALTHY, n = 30) and individuals with primary hypertension (HTN) and overweight/obesity (n = 218); assess the effects of an aerobic exercise intervention on physical activity (PA), sedentary behavior (SB), and sleep quality in the HTN group; and evaluate the relationship between objectively measured and subjectively reported PA and SB. Methods: The measurements were performed before a 16-week exercise intervention …

Murmurs Of Revolution: Mythical Subversion In Dostoevsky, Connor Guetersloh

English (MA) Theses

Throughout history, revolutions have been plagued by unpredictability; it is all but impossible to know when cultural systems will be turned on their heads. Is there a common motivator, to predict social unrest bubbling beneath the surface of society? I suggest the development of this motivator is detectable by deconstructing Ferdinand de Saussure’s semiotic patterns within the field of rhetorical mythology. “Mythology,” in the rhetorical and linguistic sense developed by Roland Barthes, is the study of a collective system of thinking we subconsciously subscribe to when interpreting meaning, perpetuated by greater society. The struggle for meaning is split into the …

Prion Protein Lowering Is A Disease-Modifying Therapy Across Prion Disease Stages, Strains And Endpoints, Eric Vallabh Minikel, Hien T. Zhao, Jason Le, Jill O'Moore, Rose Pitstick, Samantha Graffam, George A. Carlson, Michael P. Kavanaugh

Biomedical and Pharmaceutical Sciences Faculty Publications

Lowering of prion protein (PrP) expression in the brain is a genetically validated therapeutic hypothesis in prion disease. We recently showed that antisense oligonucleotide (ASO)-mediated PrP suppression extends survival and delays disease onset in intracerebrally prion-infected mice in both prophylactic and delayed dosing paradigms. Here, we examine the efficacy of this therapeutic approach across diverse paradigms, varying the dose and dosing regimen, prion strain, treatment timepoint, and examining symptomatic, survival, and biomarker readouts. We recapitulate our previous findings with additional PrP-targeting ASOs, and demonstrate therapeutic benefit against four additional prion strains. We demonstrate that

Dawn Of The Undead Classroom: Pop-Culture In The First-Year Composition Classroom, Sierra A. Ellison

English (MA) Theses

Supplemented by the findings of her IRB certified research project, Sierra A. Ellison delves into the positive effects pop culture and genre have on the first-year composition classroom, exploring how engaging students through a common discourse that is relatable and comfortable can aid in their writing and composition progression. She explains how teaching under a framework such as the undead and examining these types of thematic material can engage students in the material and give students the space to open up about key issues like race, sex, politics, morality, and consumerism that they might be reluctant to discuss otherwise.

Monarch Science Observer, Volume 5, College Of Sciences, Old Dominion University

College of Sciences Newsletter

August-Summer 2020 issue of Monarch Science Observer, ODU College of Sciences Newsletter.

Teosinte (Zea Mays Ssp Parviglumis) Growth And Transcriptomic Response To Weed Stress Identifies Similarities And Differences Between Varieties And With Modern Maize Varieties, S. A. Bruggeman, D. P. Horvath, A. Y. Fennell Dr, J. A. Gonzalez-Hernandez, S. A. Clay

Agronomy, Horticulture and Plant Science Faculty Publications

Transcriptomic responses of plants to weed presence gives insight on the physiological and molecular mechanisms involved in the stress response. This study evaluated transcriptomic and morphological responses of two teosinte (Zea mays ssp parviglumis) (an ancestor of domesticated maize) lines (Ames 21812 and Ames 21789) to weed presence and absence during two growing seasons. Responses were compared after 6 weeks of growth in Aurora, South Dakota, USA. Plant heights between treatments were similar in Ames 21812, whereas branch number decreased when weeds were present. Ames 21789 was 45% shorter in weedy vs weed-free plots, but branch numbers were similar between …

Alzheimer's Disease And Immune Cell Dysfunction, David Hansen

BYU Research Development Office Research Networking Conference

No abstract provided.

Understanding Host-Pathogen Interactions, Brett E. Pickett

BYU Research Development Office Research Networking Conference

Gene Expression, Signaling Pathway Analysis, RNA-Sequencing, Drug Repurposing, Infectious Diseases, Diagnostics, Human Diseases, Genome Assembly, Comparative Genomics, Machine Learning

Synthesis Of Alpha-Methylselenocysteine, Its Relevant Analogues, And An Unnatural Glutathione Disulfide Core, Robert J. Wehrle

Dissertations

Selenoproteins, such as glutathione peroxidase, have gained interest for their ability to act as antioxidants, and their potential to act as anti-cancer agents. Synthesizing and studying selenoproteins can be problematic, however, due to their propensity to degrade from over-oxidation. The degradation from over-oxidation can be avoided by the incorporation of the unnatural amino acid, alpha-methylselenocysteine. A synthesis utilizing methyl malonic esters was used to synthesize protected (R)-alpha-methylselenocysteine efficiently (46% over four steps) and in high enantio-purity (88% enantiomeric excess). Using similar procedures, the (S)-enantiomer was also synthesized as well as a beta-analogue.

The use of enzymes …

Merging Two Scales: A Comprehensive Measure Of Physical Appearance-Related Social Anxieties, Kimberly Smith

Dissertations

Physical appearance-related social anxieties have been identified as feelings individuals experience in general and in different social situations based on their outward appearance. Two instruments have been used to assess the construct of social anxiety, the social physique anxiety scale (SPAS) and the social appearance anxiety scale (SAAS). This cross-sectional study implemented a non-experimental design with randomization of the total sample (n=1214) into three equal groups. Participants were recruited using a crowdsource sampling platform, MTurk. This study was broken into three Phases: confirming the factor models for the SPAS and SAAS, using an exploratory technique to determine the factor structure …

Teacher Beliefs And The Intent And Current Use Of Movement As It Influences Students With And Without Adhd, Kimberly Mcquagge

Dissertations

The purpose of this study was to add to the knowledge base regarding utilizing movement in the classroom as it influences reading and mathematics achievement for students with and without Attention-Deficit Hyperactivity Disorder. Mississippi public school teachers (n= 379) responded to an online questionnaire that gathered demographic data and collected ratings based on teacher beliefs and both their current use of movement and intent to use movement in the classroom based on a 5-point Likert scale.

In order to predict if a relationship existed between teacher beliefs of utilizing movement in the classroom and both their current use of movement …