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Evaluation Of Engineered Thermal Refuge In Streams As A Climate Warming Mitigation Strategy For Fish Populations Experiencing Thermal Stress, Rebekah Thielman

Master's Theses

Rising summer stream temperatures threaten the habitat of cold-water fishes globally. Streams with cold groundwater seeps can provide thermal refuge, however natural groundwater discharge is often patchy throughout watersheds, impacting habitat connectivity. This research was undertaken to evaluate the potential to engineer (active pumping) thermal refuge that mimic cold groundwater seeps under a range of natural streamflow conditions and varying cold-water injection rates. Natural groundwater averaging 10 °C was pumped into the river channel behind a removable baffle, used to inhibit mixing and dispersal of the groundwater plume. A fiber-optic distributed temperature sensing cable was deployed above the streambed, downstream …

Does Immigration Help To Explain Child Stress?, Elizabeth Marie Koch Sigler

Theses and Dissertations

The impacts of childhood stressors are harmful to the emotional and physical well-being of children of all ages. Past research has suggested that children experience increased stress due to change. One subgroup of the United States population that experiences change, is immigrants. Research provides empirical evidence of adolescent immigrant stress but has failed to examine stress experienced by immigrant children at a young age. The present study investigates how immigration status and child immigration generation might impact child stress at a young age using OLS regression. I predict that immigrant children will experience more stress than non-immigrant children and that …

Valproic Acid Leads To An Increase In Ros Generation By Inhibiting The Deacetylation Of Mitochondrial Sod, Stephen Marc Lucas

Theses and Dissertations

Valproic Acid Promotes Acetylation of Superoxide Dismutase-2 During Neurogenesis. Valproic acid (VPA) is a known developmental toxicant associated with a high prevalence of neural tube defects (NTD). The mechanism of VPA-induced NTD is unclear, but oxidative stress may be implicated. To understand how embryotoxic oxidative stress may occur, we measured superoxide dismutase (SOD) activity following VPA treatment in the embryonic pluripotent P19 mouse carcinoma cell line. In undifferentiated P19 cultures treated with VPA (5 mM), dichlorofluorescein fluorescence increased 15% compared to untreated controls over 20 min, indicating a modest, yet statistically significant increase in ROS generation. Undifferentiated P19 cells were …

A Content Analysis Of Sexuality-Related Scholarship For Sexual Minorities, Chelise Fox

Theses and Dissertations

Sexual minority individuals face disparities of treatment from clinical and medical health professionals. In particular, there is a dearth of research and training surrounding human sexuality topics for sexual minorities. Research on sexual minority groups in this area can contribute to reducing treatment disparities. Consequently, the proposed study is a content analysis of social science literature in order to gauge trends in the amount of research focused on the intersection of sexual minorities and sex research. Articles from a database search of relevant keywords were coded for several variables, including overall level of focus on sexual minorities and on human …

Discovery Of A Novel Regulatory Mechanism Of Tnk1 By 14-3-3 And Its Ubiquitin Association Domain Provides A Potential Therapeutic Targeting Opportunity In Cancer, Tsz Yin Chan

Theses and Dissertations

While a relatively limited number of known oncogenes underlie a large percentage of cancers, a variety of new genes have emerged as low-frequency cancer drivers. Each of these new oncogenes represents a frontier for targeted therapy. However, the discovery of low-frequency targetable oncogenic drivers is challenging. This study focuses on the poorly understood Tyrosine kinase non-receptor-1 (TNK1), which has been reported to have both oncogenic and tumor suppressive functions. TNK1 has been identified to promote cancer cells survival and promote chemoresistance in multiple independent studies. On the other hand, whole-body constitutive deletion of TNK1 in mice caused an increase in …

Effect Of Using A Nitrogen Atmosphere On Enzyme Hydrolysis At High Corn Stover Loadings In An Agitated Reactor, Antonio Carlos Freitas Dos Santos, Eduardo Ximenes, David Thompson, Allison E. Ray, Ryan Szeto, Kendra Erk, Bruce S. Dien, Michael R. Ladisch

School of Materials Engineering Faculty Publications

A comprehensive review of the literature shows that enzyme hydrolysis efficiency decreases with increased solids loadings at constant enzyme:cellulose ratios for pretreated lignocellulosic substrates. In seeking a mechanistic explanation for this phenomenon, we found that a nitrogen atmosphere enhances enzyme hydrolysis and minimizes the decrease in glucose yields as solids loadings are increased in an agitated bioreactor. For liquid hot water pretreated corn stover, at solids loadings of both 100 and 200 g/L and hydrolyzed for 72 hr in a 1 L bioreactor at pH 5.0 with 3.6 mg protein per g biomass, glucose yields were 55% in a nitrogen …

Imidacloprid Movement Into Fungal Conidia Is Lethal To Mycophagous Beetles, Robin A. Choudhury, Andrew M. Sutherland, Matt J. Hengel, Michael P. Parrella, W. Douglass Gubler

School of Earth, Environmental, & Marine Sciences Faculty Publications

Applications of systemic pesticides can have unexpected direct and indirect effects on nontarget organisms, producing ecosystem-level impacts. We investigated whether a systemic insecticide (imidacloprid) could be absorbed by a plant pathogenic fungus infecting treated plants and whether the absorbed levels were high enough to have detrimental effects on the survival of a mycophagous beetle. Beetle larvae fed on these fungi were used to assess the survival effects of powdery mildew and imidacloprid in a factorial design. Fungal conidia were collected from treated and untreated plants and were tested for the presence and concentration of imidacloprid. The survival of beetles fed …

Emergent Risks In The Mt. Everest Region In The Time Of Anthropogenic Climate Change, Kr Miner, Pa Mayewski, Sk Baidya, K Broad, H Clifford, Ap Gajurel, B Giri, M Hubbard, C Jaskolski, H Koldewey, W Li, T Matthews, I Napper, B Perry, M Potocki, Jc Priscu, A Tait, R Thompson, S Tuladhar

School of Biological and Marine Sciences

No abstract provided.

Understanding Relapse In Self-Perceived Problematic Pornography Users, Erin L. Rackham

Theses and Dissertations

This study explored reasons for relapse among a sample of 938 self-identified problematic pornography users. A combination of numeric content analysis and qualitative coding of responses to an open-ended question about pornography relapse revealed six main categories of reasons for relapse. The mental, emotional, and relational categories were then analyzed in detail, and this analysis revealed significant overlap of responses from the emotional and relational categories. Hence, a new category of relational-emotional reasons for relapse was created and analyzed. The findings from this study highlight the complex interactions of different types of factors driving relapse in self-perceived problematic pornography users …

Nanostructured Flame Retardant Coatings, Brandon Williams

Doctoral Dissertations

Fires account for approximately 3100 deaths and $10 billion in property damage annually in the US. Growing consumption of polymeric materials increases the potential damage a fire could cause. Halogenated chemicals have dominated as the primary means of flame retarding (FR) polymeric materials since the 1960s. However, regulation has required they be phased out of use, directing research towards halogen-free FR solutions. One emerging technology is nanocoatings. Nanocoatings are currently processed using direct mixing, in situ polymerization, and layer-by-layer deposition in attempts to achieve well-organized and highly dispersed nanosheets. These processing methods are limited by efficiency and scalability. Recently a …

How Do They Feel About It? Testing A New Mixed Methods Survey Tool To Assess Collective Emotional Status, Michael G. Schwab, Vasileios Margaritis

The Qualitative Report

Emotions are now widely accepted as important elements of qualitative research, in studies of individuals and communities. However, collective emotional status—what a community feels about a given situation or proposition—can be challenging to assess. In this study, we examined the validity and acceptability of a new mixed methods survey tool, primarily qualitative, to address this challenge—the Assessment of Collective Emotional Status (ACES). The tool begins with an adjustable set of questions about emotion, to draw respondents’ attention to their own feelings. These are followed by an emotional self-assessment, in which respondents select and prioritize five emotional responses to a standardized …

Sarm1 Acts Downstream Of Neuroinflammatory And Necroptotic Signaling To Induce Axon Degeneration, Kwang Woo Ko, Jeffrey Milbrandt, Aaron Diantonio

Open Access Publications

Neuroinflammation and necroptosis are major contributors to neurodegenerative disease, and axon dysfunction and degeneration is often an initiating event. SARM1 is the central executioner of pathological axon degeneration. Here, we demonstrate functional and mechanistic links among these three pro-degenerative processes. In a neuroinflammatory model of glaucoma, TNF-α induces SARM1-dependent axon degeneration, oligodendrocyte loss, and subsequent retinal ganglion cell death. TNF-α also triggers SARM1-dependent axon degeneration in sensory neurons via a noncanonical necroptotic signaling mechanism. MLKL is the final executioner of canonical necroptosis; however, in axonal necroptosis, MLKL does not directly trigger degeneration. Instead, MLKL induces loss of the axon survival …

Wombling For Spatial And Spatiotemporal Processes: Applications To Insurance Data, Aritra Halder

Doctoral Dissertations

In this dissertation we focus on developing a framework for detecting zones of rapid change within a surface that is spatially or spatiotemporally indexed, which is termed as wombling. This is considered under two different approaches featuring a semi-parametric model and a model based parametric setup. The second approach starts with a Gaussian process specification on the spatial or spatiotemporal component. We focus on applying the developed framework to build models for analyzing spatiotemporally referenced insurance data arising from losses due to automobile collision in the state of Connecticut, in the year 2008. For the semi-parametric models we adopt a …

Photographic Confirmation Of Crested Guan (Penelope Purpurascens) From A Relict Maple Forest In Western Mexico, Alejandro Pérez-Arteaga, S. Alejandra Mora-Sánchez, Sylvia S. Zalapa, Sergio Guerrero-Vázquez

Western North American Naturalist

The Crested Guan (Penelope purpurascens) is globally decreasing and endangered in Mexico. Here we report new records (8 adults and 2 juveniles) from a protected relict maple forest (critically endangered Acer binzayedii) in Parque Estatal Bosque de Arce (PEBA), Talpa de Allende, Jalisco, Mexico. Our results confirm the continuous presence of the Crested Guan over the last 2 years and the existence of reproductive activity in the study area. Our results also highlight the relevance of the species in this fragile, imperiled habitat.


La pava cojolita (Penelope purpurascens) se encuentra en declive a nivel global …

Sediment‐Induced Stratification In An Estuarine Bottom Boundary Layer, G Egan, Aj Manning, G Chang, O Fringer, S Monismith

School of Biological and Marine Sciences

We took field observations on the shallow shoals of South San Francisco Bay to examine how sediment-induced stratification affects the mean flow and mixing of momentum and sediment throughout the water column. A Vectrino Profiler measured near-bed velocity and suspended sediment concentration profiles, which we used to calculate profiles of turbulent sediment and momentum fluxes. Additional turbulence statistics were calculated using data from acoustic Doppler velocimeters placed throughout the water column. Results showed that sediment-induced stratification, which was set up by strong near-bed wave shear, can reduce the frictional bottom drag felt by the mean flow. Measured turbulence statistics suggest …

Analyzing Metacommunity Models With Statistical Variance Partitioning: A Review And Meta-Analysis, Kevin Vieira Lamb

Theses and Dissertations

The relative importance of deterministic processes versus chance is one of the most important questions in science. We analyze the success of variance partitioning methods used to explain variation in β-diversity and partition it into environmental, spatial, and spatially structured environmental components. We test the hypotheses that 1) the number of environmental descriptors in a study would be positively correlated with the percentage of β-diversity explained by the environment, and that the environment would explain more variation in β-diversity than spatial or shared factors in VP analyses, 2) increasing the complexity of environmental descriptors would help account for more of …

Interactions Of Photosensitizers With Model Membranes And Their Applications In Photodynamic Therapy, Poornima Kalyanram

Theses

Cancer is caused by the uncontrolled growth and spread of abnormal cells resulting in 1 in 6 deaths every day. The most common treatment methods include surgery, chemotherapy, and radiation. These techniques are invasive, aggressive, and non-specific to cancer cells. Therefore, alternative therapies which are both potent and does not interfere with the quality of living are on a rise. Photodynamic Therapy (PDT) is an approved alternative remedy in the treatment of cancer. The efficacy of PDT depends on the penetration power of the photosensitizer (PS) when injected into to the site of tumor. However, due to complexity involved in …

Synthesis And Assessment Of Radiotherapy-Enhancing Nanoparticles, Hayden Winter

Dissertations and Theses

Radiation Therapy (RT) is a common treatment for cancerous lesions that acts by ionizing matter in the affected tissue, causing cell death. The disadvantage of RT is that it is most often delivered via an external beam of radiation which must pass through healthy tissues to reach the target site, ionizing matter within healthy tissues as well. To address this drawback, techniques are being developed for increasing RT-induced cell death in a target tissue while minimizing cell death in surrounding tissues. This effect is known as radiation dose enhancement or RT enhancement.

The approach to RT enhancement studied in this …

A Global Slc7a7 Knockout Mouse Model Demonstrates Characteristic Phenotypes Of Human Lysinuric Protein Intolerance, Bridget M Stroup, Ronit Marom, Xiaohui Li, Chih-Wei Hsu, Cheng-Yen Chang, Luan D Truong, Brian Dawson, Ingo Grafe, Yuqing Chen, Ming-Ming Jiang, Denise Lanza, Jennie Rose Green, Qin Sun, J P Barrish, Safa Ani, Audrey E Christiansen, John R Seavitt, Mary E Dickinson, Farrah Kheradmand, Jason D Heaney, Brendan Lee, Lindsay C Burrage

Faculty, Staff and Students Publications

Lysinuric protein intolerance (LPI) is an inborn error of cationic amino acid (arginine, lysine, ornithine) transport caused by biallelic pathogenic variants in SLC7A7, which encodes the light subunit of the y+LAT1 transporter. Treatments for the complications of LPI, including growth failure, renal disease, pulmonary alveolar proteinosis, autoimmune disorders and osteoporosis, are limited. Given the early lethality of the only published global Slc7a7 knockout mouse model, a viable animal model to investigate global SLC7A7 deficiency is needed. Hence, we generated two mouse models with global Slc7a7 deficiency (Slc7a7em1Lbu/em1Lbu; Slc7a7Lbu/Lbu and Slc7a7em1(IMPC)Bay/em1(IMPC)Bay; Slc7a7Bay/Bay) using CRISPR/Cas9 technology by introducing a deletion of exons …

Nutrient Dynamics In A Semi‐Arid Grazing Land Of Southern India, K. Karunaichamy, Kailash Paliwal

IGC Proceedings (1977-2023)

No abstract provided.

Effects Of Grazing On Am Colonization And Spore Density In Arid Grasslands Of Loess Plateau, Liang Jin, Chang Wang, Fujiang Hou, Shenghua Chang, Guiqi Zhang, Xiaojuan Wang

IGC Proceedings (1977-2023)

No abstract provided.

P And K Effects On N Partitioning During Regrowth Of Italian Ryegrass, Y. L. Jin, B. R. Lee, M. Li, W. J. Jung, T. H. Kim

IGC Proceedings (1977-2023)

No abstract provided.

Impacts Of Long‐Term Enclosure On Soil Microbes In Mountain‐Pasture In Bayinbuluke, Ping'an Jiang

IGC Proceedings (1977-2023)

No abstract provided.

10 Theses On Feminist Economics (Or The Antagonism Between The Strike And Finance), Luci Cavallero, Verónica Gago

CLCWeb: Comparative Literature and Culture

In their article, “10 Theses on Feminist Economics (or the antagonism between the strike and finance),” Luci Cavallero and Verónica Gago are interested in a feminist economics that is able to redefine, based on the bodies and territories in conflict, labor and exploitation, communal and feminized modes of doing and resisting, and popular innovation in moments of crisis. They write from the position of having formed part of the organizing for the feminist strike that, since 2016, has driven what they characterize as a massive, radical, and transnational movement. They root the theses that they synthesize here in that dynamic …

Detroit’S Water Wars: Race, Failing Social Reproduction, And Infrastructure, Brian Whitener

CLCWeb: Comparative Literature and Culture

In this essay, I theorize an emergent urban power dynamic of infrastructural resource grabs or the use of state power to transfer infrastructural resources away from marginalized, racialized, and/or precariously documented populations. As a transfer, rather than a set of cuts or privatizations, I argue this dynamic is distinct from those of neoliberal or “shrinking” states and is a direct attack on the social reproduction capacity of communities and individuals. Focusing on the case of Detroit, where predominantly white suburban elites succeeded under the cover of Detroit’s 2013-14 bankruptcy proceedings to pry the possession of the water and sewage infrastructure …

Social Reproduction Theory And The Form Of Labor Power, Aaron Jaffe

CLCWeb: Comparative Literature and Culture

Social Reproduction Theory (SRT) centers the production and reproduction of labor power under capitalism. This power to labor is determined individually, socially, and in relation to the totality of capital. These powers are produced and reproduced in and through social relations that, while capitalist, have tremendously diverse local conditions and histories. SRT provides a framework to think through the oppressive logics shaping the production, reproduction, and potencies of labor powers understood as diversely constituted. It argues that SRT is committed to the diversity of these labor powers over and against conditions that constrain both these powers and their actualizations in …

Social Reproduction In The Making: Recentering The Margins, Expanding The Directions, Zhivka Valiavicharska

CLCWeb: Comparative Literature and Culture

This essay aims to broaden existing historical narratives of social reproduction by revisiting Black-feminist, postcolonial feminist, and migrant diasporic writings on social reproduction from the 1970s onwards. Centering on the historical experience of women of color, migrant communities, and women in postcolonial contexts and other parts of the world, these writings develop much-needed critiques of dominant social reproduction themes developed in the capitalist contexts in Western Europe and North America. These alternative feminist methodologies and historical accounts add important correctives to what is becoming the main corpus of social reproduction theory and its historiography today. They contain political potentials that …

An Experimental Clil Course For Moroccan Students Preparing For The International Baccalaureate, Amine Bouhzam

MA TESOL Collection

The author of this thesis aims to investigate Content and Language Integrated Learning (CLIL) approach for seniors (grade 12) in the Moroccan EFL classroom. The field of science has been broken into range of specialisms which influence students’ choices for the international Baccalaureate in which the language of instruction is either French, English or Spanish. Being so, the approach acts as the backbone for the study of certain content through specific language use (Dalton-Puffer: 2007).

The intent of the thesis is to explore the instructor's thorough processes in starting the project, his desires, encounters and difficulties, and the long-term impact …

Stormwater Capture Via Green Infrastructure In The Plaster Creek Watershed, Brett Barents, Kiara Bromley, Haley Weesies, Deanna Geelhoed, David P. Warners

Student Papers and Reports

No abstract provided.

Validation Of Spatiotemporal And Kinematic Measures In Functional Exercises Using A Minimal Modeling Inertial Sensor Methodology, Benjamin R. Hindle, Justin W.L. Keogh, Anna V. Lorimer

Open Access archive

This study proposes a minimal modeling magnetic, angular rate and gravity (MARG) methodology for assessing spatiotemporal and kinematic measures of functional fitness exercises. Thirteen healthy persons performed repetitions of the squat, box squat, sandbag pickup, shuffle-walk, and bear crawl. Sagittal plane hip, knee, and ankle range of motion (ROM) and stride length, stride time, and stance time measures were compared for the MARG method and an optical motion capture (OMC) system. The root mean square error (RMSE), mean absolute percentage error (MAPE), and Bland–Altman plots and limits of agreement were used to assess agreement between methods. Hip and knee ROM …