Digital Commons Network^™

Patterns For Populus Spp. Stand Biomass In Gradients Of Winter Temperature And Precipitation Of Eurasia, Vladimir Andreevich Usoltev, Baozhang Chen, Seyed Omid Reza Shobairi, Ivan Stepanovich Tsepordey, Viktor Petrovich Chasovskikh, Shoaib Ahmad Anees

Aspen Bibliography

Based on a generated database of 413 sample plots, with definitions of stand biomass of the genus Populus spp. in Eurasia, from France to Japan and southern China, statistically significant changes in the structure of forest stand biomass were found, with shifts in winter temperatures and average annual precipitation. When analyzing the reaction of the structure of the biomass of the genus Populus to temperature and precipitation in their transcontinental gradients, a clearly expressed positive relationship of all components of the biomass with the temperature in January is visible. Their relationship with precipitation is less clear; in warm climate zones, …

Phosphorylation Of Cyclophilin D At Serine 191 Regulates Mitochondrial Permeability Transition Pore Opening And Cell Death After Ischemia-Reperfusion, Stephen Hurst, Fabrice Gonnot, Maya Dia, Claire Crola Da Silva, Ludovic Gomez, Shey-Shing Sheu

Department of Medicine Faculty Papers

The mitochondrial permeability transition pore (mPTP) plays a critical role in the pathogenesis of cardiovascular diseases, including ischemia/reperfusion injury. Although the pore structure is still unresolved, the mechanism through which cyclophilin D (CypD) regulates mPTP opening is the subject of intensive studies. While post-translational modifications of CypD have been shown to modulate pore opening, specific phosphorylation sites of CypD have not yet been identified. We hypothesized here that phosphorylation of CypD on a serine residue controls mPTP opening and subsequent cell death at reperfusion. We combined in silico analysis with in vitro and genetic manipulations to determine potential CypD phosphorylation …

Tracing Ripples: The Impact Of Parent Aces On Next Generation Development And The Moderating Role Of Parent Resilience, Laura M. Hoffman

Doctor of Psychology (PsyD)

Adverse childhood experiences (ACEs) impact individual well-being at a biopsychosocial level and can undermine next generation child development. Resilience is increasingly understood to be achieved through natural adaptive systems, though younger children may be more reliant on environmental adaptive systems as internal systems develop. Parent resilience is a promising moderator of early intergenerational trauma transmission but relatively unexplored in terms of safeguarding offspring developmental outcomes. The current study examined if parent ACEs impact offspring overall development and specific developmental domains at 9, 18, and 30 months, and if parent resilience moderates these effects. A series of multiple linear regression, MANOVA, …

A Grounded Theory Of The Impact Of Teachnj On The Instructional Leadership Of Superintendents, Russell Matthew Lazovick

Theses and Dissertations

The purpose of this grounded theory study was to develop a theory, grounded in data obtained by interviewing current superintendents on how TEACHNJ has impacted their ability to improve student performance. TEACHNJ is a law enacted by the state of New Jersey to improve teacher quality and raise student performance by changing evaluation and tenure processes in order to create greater transparency, equity, consistency, and accountability across districts. This study examined the law's impact on five specific actions superintendents can take that have been found to enhance student performance. The study found that TEACHNJ served as a punctuating event, sending …

Dectin-1 Mediated Mechanical Force Generation In Candida Albicans Fungal Pathogen Recognition, Rohan Choraghe

Biomedical Engineering ETDs

Candida spp. pathogens continue to be a major health care burden with high mortality and exceeding a billion dollars in terms of healthcare cost. Candidainfection ranges from superficial dermatological infection to more serious blood stream infection in debilitated patients. One of the major lines of innate immune defense against Candidais phagocytosis. Dectin-1 is the antifungal receptor in myeloid cells responsible for most immune responses against fungi including phagocytosis. We looked into the signaling pathway coordinating this mechanical process downstream of Dectin-1. We found that Dectin-1 activation gives rise to a significant mechanical force generation mediated through RHOA-ROCK-MyosinII pathway. …

Is Host Metabolism The Missing Link To Improving Cancer Outcomes?, Christopher M Wright, Anuradha A. Shastri, Emily K Bongiorno, Ajay Palagani, Ulrich Rodeck, Nicole L Simone

Kimmel Cancer Center Faculty Papers

For the past 100 years, oncologists have relentlessly pursued the destruction of tumor cells by surgical, chemotherapeutic or radiation oncological means. Consistent with this focus, treatment plans are typically based on key characteristics of the tumor itself such as disease site, histology and staging based on local, regional and systemic dissemination. Precision medicine is similarly built on the premise that detailed knowledge of molecular alterations of tumor cells themselves enables better and more effective tumor cell destruction. Recently, host factors within the tumor microenvironment including the vasculature and immune systems have been recognized as modifiers of disease progression and are …

Dementia-Related Psychosis And The Potential Role For Pimavanserin, Jeffery L. Cummings, D. P. Devanand, Stephen M. Stahl

School of Medicine Faculty Research

Dementia-related psychosis is prevalent across dementias and typically manifests as delusions and/or hallucinations. The mechanisms underlying psychosis in dementia are unknown; however, neurobiological and pharmacological evidence has implicated multiple signaling pathways and brain regions. Despite differences in dementia pathology, the neurobiology underlying psychosis appears to involve dysregulation of a cortical and limbic pathway involving serotonergic, GABAergic, glutamatergic, and dopaminergic signaling. Thus, an imbalance in cortical and mesolimbic excitatory tone may drive symptoms of psychosis. Delusions and hallucinations may result from (1) hyperactivation of pyramidal neurons within the visual cortex, causing visual hallucinations, and (2) hyperactivation of the mesolimbic pathway, causing …

The Emotional Impact Of The Covid-19 Pandemic On Individuals With Progressive Multiple Sclerosis, Nancy D. Chiaravalloti, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Ulrik Dalgas, John Deluca, Cecilia Meza, Nancy B. Moore, Peter Feys, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Rob Motl, Maria Assunta Rocca, Brian M. Sandroff, Amber Salter, Gary Cutter, Anthony Feinstein

School of Health Professions

No abstract provided.

Office Of Research, Economic Engagement And Outreach Update, August 19, 2020, Office Of Research, Economic Engagement And Outreach

Office of Research, Economic Engagement and Outreach

No abstract provided.

Effect Of Boron Fertilizer On Density, Growth, Seed Yield And Nutrient Concentrations Of Centrosema Pubescens Grown In Humid Subtropical Areas Of Yunnan In China, Meifen Huang, Zhanxing He, Jiaxiang Kui, Yi Zheng, Ziwei Zhou, Kehui Lin

IGC Proceedings (1977-2023)

No abstract provided.

Effects Of Yearly Simulated Temperature Rise And Nitrogen Deposition On Soil Nutrient In The Songnen Meadow Steppes Of Northeast China, L. J. Hu, D. L. Wang, W. W. Wang, J. X. Guo

IGC Proceedings (1977-2023)

No abstract provided.

Effects Of Microbiotic Crust Nutrients On The Different Vegetations, Zhi He, Yong Gao, Hailong Zhang, Ruiping Zhou, Zhiying Mi

IGC Proceedings (1977-2023)

No abstract provided.

A Strategy To Predict The Global Warming Gas From Stock Farming —Potential Scaling Law Of The Released Methane From Livestock—, Toshiaki Nakashima, Tsuneyoshi Matsuoka, Yuji Nakamura

Progress in Scale Modeling, an International Journal

This work examines a scaling approach to predict the amount of methane released from the daily activity of livestock on farms. The subject animals are ruminants, i.e. having rumen or a ruminant stomach, that generates methane through digestion processes via several microbial fermentation steps. The produced methane is mixed into their breathing and released into the atmosphere. Existing data on methane released from various kinds of ruminant livestock were correlated as a power function of an animal’s weight, with an exponent near 0.92. This value is larger than a value of 0.75 which was related to the general metabolism rates …

Proceedings For Conservation Of Fragile Karst Resources, Crawford Hydrology Laboratory, The George Wright Society, Mammoth Cave National Park

Conservation of Fragile Karst Resources Proceedings

A Workshop on Sustainability and Community in support of UNESCO science programs August 18-20, 2020

An Input Power-Aware Maximum Efficiency Tracking Technique For Energy Harvesting In Iot Applications, Sanad Fares Yousef Kawar

Engineering Ph.D. Theses

The Internet of Things (IoT) enables intelligent monitoring and management in many applications such as industrial and biomedical systems as well as environmental and infrastructure monitoring. As a result, IoT requires billions of wireless sensor network (WSN) nodes equipped with a microcontroller and transceiver. As many of these WSN nodes are off-grid and small-sized, their limited-capacity batteries need periodic replacement. To mitigate the high costs and challenges of these battery replacements, energy harvesting from ambient sources is vital to achieve energy-autonomous operation. Energy harvesting for WSNs is challenging because the available energy varies significantly with ambient conditions and in many …

August 17-18, 2020, Ohio University Board Of Trustees Meeting Minutes, Ohio University Board Of Trustees

Board of Trustees Meeting Minutes

Meeting minutes document the activities of Ohio University's Board of Trustees.

Dynamics Of The Ace2 - Sars-Cov-2/Sars-Cov Spike Protein Interface (Issue 20, 18 August 2020), Amanat Ali, Ranjit Vijayan

Covid19 Newsletters

No abstract provided.

Associations Between High-Density Lipoprotein Particles And Ischemic Events By Vascular Domain, Sex, And Ethnicity: A Pooled Cohort Analysis, Kavisha Singh, Alvin Chandra, Thomas Sperry, Parag H. Joshi, Amit Khera, Salim S. Virani, Christie M. Ballantyne, James D. Otvos, Robin P F. Dullaart, Eke G. Gruppen

Office of the Provost

Background: High-density lipoprotein (HDL) cholesterol concentration (HDL-C) is an established atheroprotective marker, in particular for coronary artery disease; however, HDL particle concentration (HDL-P) may better predict risk. The associations of HDL-C and HDL-P with ischemic stroke and myocardial infarction (MI) among women and Blacks have not been well studied. We hypothesized that HDL-P would consistently be associated with MI and stroke among women and Blacks compared with HDL-C.
Methods: We analyzed individual-level participant data in a pooled cohort of 4 large population studies without baseline atherosclerotic cardiovascular disease: DHS (Dallas Heart Study; n=2535), ARIC (Atherosclerosis Risk in Communities; n=1595), MESA …

Foliar Application Of Low Concentrations Of Titanium Dioxide And Zinc Oxide Nanoparticles To The Common Sunflower Under Field Conditions, Marek Kolenčík, Dávid Ernst, Martin Urík, Ľuba Ďurišová, Marek Bujdoš, Martin Šebesta, Edmund Dobročka, Samuel Kšiňan, Ramakanth Illa, Qian Yu, Huan Feng, Ivan Černý, Veronika Holišová, Gabriela Kratošová

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Nano-fertilisers have only recently been introduced to intensify plant production, and there still remains inadequate scientific knowledge on their plant-related effects. This paper therefore compares the effects of two nano-fertilisers on common sunflower production under field conditions. The benefits arising from the foliar application of micronutrient-based zinc oxide fertiliser were compared with those from the titanium dioxide plant-growth enhancer. Both the zinc oxide (ZnO) and titanium dioxide (TiO₂) were delivered by foliar application in nano-size at a concentration of 2.6 mg·L⁻¹. The foliar-applied nanoparticles (NPs) had good crystallinity and a mean size distribution under 30 nm. …

Atlas Of Transcription Factor Binding Sites From Encode Dnase Hypersensitivity Data Across 27 Tissue Types., Cory C Funk, Alex M Casella, Segun Jung, Matthew A Richards, Alex Rodriguez, Paul Shannon, Rory Donovan-Maiye, Ben Heavner, Kyle Chard, Yukai Xiao, Gustavo Glusman, Nilufer Ertekin-Taner, Todd E Golde, Arthur Toga, Leroy Hood, John D Van Horn, Carl Kesselman, Ian Foster, Ravi Madduri, Nathan D Price, Seth A Ament

Articles, Abstracts, and Reports

Characterizing the tissue-specific binding sites of transcription factors (TFs) is essential to reconstruct gene regulatory networks and predict functions for non-coding genetic variation. DNase-seq footprinting enables the prediction of genome-wide binding sites for hundreds of TFs simultaneously. Despite the public availability of high-quality DNase-seq data from hundreds of samples, a comprehensive, up-to-date resource for the locations of genomic footprints is lacking. Here, we develop a scalable footprinting workflow using two state-of-the-art algorithms: Wellington and HINT. We apply our workflow to detect footprints in 192 ENCODE DNase-seq experiments and predict the genomic occupancy of 1,515 human TFs in 27 human tissues. …

Influence Of External Nacl Salt On Membrane Rigidity Of Neutral Dopc Vesicles, Judith U. De Mel, Sudipta Gupta, Rasangi M. Perera, Ly Ngo, Piotr Zolnierczuk, Markus Bleuel, Sai Venkatesh Pingali, Gerald J. Schneider

Faculty Publications

Copyright © 2020 American Chemical Society. Sodium chloride (NaCl) is a very common molecule in biotic and abiotic aqueous environments. In both cases, variation of ionic strength is inevitable. In addition to the osmotic variation posed by such perturbations, the question of whether the interactions of monovalent ions Na+ and Cl-, especially with the neutral head groups of phospholipid membranes are impactful enough to change the membrane rigidity, is still not entirely understood. We investigated the dynamics of 1,2-di-(octadecenoyl)-sn-glycero-3-phosphocholine (DOPC) vesicles with zwitterionic neutral head groups in the fluid phase with increasing external salt concentration. At higher salt concentrations, we …

Modulation Of Escherichia Coli Translation By The Specific Inactivation Of TrnaGly Under Oxidative Stress, Lorenzo Eugenio Leiva, Andrea Pincheira, Sara Elgamal, Sandra D. Kienast, Verónica Bravo, Johannes Leufken, Daniela Gutiérrez, Sebastian A. Leidel, Michael Ibba, Assaf Katz

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Bacterial oxidative stress responses are generally controlled by transcription factors that modulate the synthesis of RNAs with the aid of some sRNAs that control the stability, and in some cases the translation, of specific mRNAs. Here, we report that oxidative stress additionally leads to inactivation of tRNA^Gly in Escherichia coli, inducing a series of physiological changes. The observed inactivation of tRNA^Gly correlated with altered efficiency of translation of Gly codons, suggesting a possible mechanism of translational control of gene expression under oxidative stress. Changes in translation also depended on the availability of glycine, revealing a mechanism whereby bacteria …

Cuckoo Search Algorithm For Extraction Ten Parameters Of Photovoltaic Models., Mokhtar Ahmed, Ahmed Osama

Mansoura Engineering Journal

the important issue in the extraction of the unknown parameters in the photovoltaic model is the mathematical models. Therefore, a five equivalent circuit is analyzed in this work. The unknown parameters are five for single diode model, seven for double-diode model, eight for modified double-diode, and nine for three-diode model and ten for modified three-diode parameters. The performance of the modified three-diode model and three-diode model after estimate all parameters without assumption for any variable are compared with the performance of the both single diode model, double-diode model and also the modified double-diode of the same solar cell. Cuckoo search …

High-Frequency Data Reveal Differential Dissolved And Suspended Solids Behavior From A Mixed Restored Prairie And Agricultural Catchment, Andrew Miller, Ashlee L. Dere, Tracy Coleman

Chemistry Faculty Publications

Quantifying temporal variability and fluxes within hydrologic catchments is critical to understanding the underlying chemical and physical processes leading to material transport. Measuring variability and fluxes requires sampling at time scales similar to the time scale of process occurrence. This demand has led to the development of automated sampling systems designed to sample at high frequencies, on the order of minutes. While widely deployed in a variety of systems, we installed two high-frequency sampling devices in a single drainage comprised of restored prairie and agricultural land uses in temperate Eastern Nebraska. The sampling systems determined flow rate, conductivity, and turbidity …

Responding To Questions Of Parents With Vaccine Concerns, Chalea Rowberry

Student Works

ABSTRACT

Introduction: Even with the benefits of vaccinations, some parents refuse vaccinations due to influence from vaccine opponents. The purpose of this article is to identify common vaccine concerns on public forums and address these concerns with scientific evidence, thereby offering PNPs information on how to respond.

Method: Six electronic databases were searched to identify articles examining concerns of parents regarding vaccines and provide evidence-based responses to each concern.

Results: Some parents are concerned that healthcare providers are not obtaining written informed consent prior to vaccinating their child(ren). Another common concern is that pharmaceutical companies are solely motivated by financial …

Interstage Home Monitoring For Infants With Single Ventricle Heart Disease: Education And Management: A Scientific Statement From The American Heart Association., Nancy A. Rudd, Nancy S. Ghanayem, Garick D. Hill, Linda M. Lambert, Kathleen A. Mussatto, Jo Ann Nieves, Sarah Robinson, Girish S. Shirali, Michelle M. Steltzer, Karen Uzark, Nancy A. Pike, American Heart Association Council On Cardiovascular And Stroke Nursing; Council On Lifelong Congenital Heart Disease And Heart Health In The Young; Council On Arteriosclerosis, Thrombosis And Vascular Biology; Council On Clinical Cardiology; And Council On Lifestyle And Cardiometabolic Health

Manuscripts, Articles, Book Chapters and Other Papers

This scientific statement summarizes the current state of knowledge related to interstage home monitoring for infants with shunt-dependent single ventricle heart disease. Historically, the interstage period has been defined as the time of discharge from the initial palliative procedure to the time of second stage palliation. High mortality rates during the interstage period led to the implementation of in-home surveillance strategies to detect physiologic changes that may precede hemodynamic decompensation in interstage infants with single ventricle heart disease. Adoption of interstage home monitoring practices has been associated with significantly improved morbidity and mortality. This statement will review in-hospital readiness for …

Spring/Summer 2020: In Case You Missed It/New Frontiers For A New Academic Year, St. Norbert College

St. Norbert College Magazine 2019-2023

We’ve been preparing for a year like no other here at St. Norbert, finding innovative ways to bring everyone back to campus safely in a COVID-19 world. Here’s a roundup of some of the things we’ve been doing and the stories we’ve shared via social media, websites or other publications since our last issue.

Spring/Summer 2020: Meet The Class Of 2024, St. Norbert College

St. Norbert College Magazine 2019-2023

The annual snapshot of the incoming freshmen class.

Spring/Summer 2020: New Data Analytics Major Launches, St. Norbert College

St. Norbert College Magazine 2019-2023

With the start of the fall semester next week, St. Norbert adds a new and rigorous data analytics major to its offerings. The curriculum is a collaboration between disciplines in the natural sciences and the Schneider School of Business & Economics, leveraging existing courses and adding new ones.

Spring/Summer 2020: Snc-Connected Co-Workers Make Sure America Eats Its Greens, St. Norbert College

St. Norbert College Magazine 2019-2023

Megan Pirelli ’13 MBA ’19 and Ashley Ponschok MBA ’19 shared ground-level experience at a food-tech start-up that’s serving up fresh greens for K-12 pupils and food pantry clients.