Digital Commons Network^™

The Soil Improvement Effect Of Afforestation In Grassland--Take Gegentala Grassland As Example, Zhongju Meng, Yong Gao, Deren Yan

IGC Proceedings (1977-2023)

No abstract provided.

Residue Effects Of Animal Manures On Forage Production And Soil Fertility After Receiving Longterm Of Manure Application, Fu‐Hsing Hsu, Kuoyuan Hong, Chihsin Lu

IGC Proceedings (1977-2023)

No abstract provided.

Biological Ways To Improve The Production Of Forage Pea For Use In The Animal Feed Industry, D. Egamberdieva, L. Gafurova

IGC Proceedings (1977-2023)

No abstract provided.

Response Of Spatial Distribution Of Phosphorus In Soil To Wetlands Restoration In Yellow River, Delta Qiuyi Ding, Junhong Bai, Haifeng Gao

IGC Proceedings (1977-2023)

No abstract provided.

Effect Of Sod‐Production On Soil Qualities In Beijing Areas, Jianyu Cui, Kangguo Mu, Yajia Liu, Lin Hu, Fusuo Zhang

IGC Proceedings (1977-2023)

No abstract provided.

Optimization Of Nitrate Removal From Aqueous Solution By Acid-Activated Rice Straw Supported Nano Zero-Valent Iron Using Response Surface Methodology, Dalia A. Ali Eng, Nagwa Mahmoud Al-Mansi Prof, Mohamed Amin Sadek Prof., Ahmad Wafiq Abolnasr Dr.

Chemical Engineering

Rice straw is one of the most common agricultural wastes due to its large production amounts. Energy valorization of rice straw is a technology used for nitrate removal as the produced ashes used to generate the adsorbent by means of an alkali dissolution followed by acid precipitation. The novelty of the proposed process is that the production of the nano zero-valent iron supported acid-activated rice straw (AARS-nZVI) adsorbent is carried out without the energy valorization process but, through an acid activation for rice straw followed by precipitation of nZVI particles on its surface. The new adsorbent synthesis, characterization and application …

Insights On Dissolved Organic Matter Production Revealed By Removal Of Charge-Transfer Interactions In Senescent Leaf Leachates, Karl M. Meingast, Brice K. Grunert, Sarah A. Green, Evan S. Kane, Nastaran Khademimoshgenani

Michigan Tech Publications, Part 1

Dissolved organic matter (DOM) is a critical part of the global carbon cycle. Currently, it is understood that at least a portion of the chromophoric DOM (CDOM) character can be described through an electronic interaction of charge transfer (CT) complexes. While much work has been done to understand the influence of CT on soil and aquatic reference standard DOM, little is known about the influence of CT in fresh terrestrially derived DOM. In this study, leaf litter leachates from three tree species were treated (reduced) with sodium borohydride to determine the contribution of CT on a source of fresh terrestrial …

Description Of The Male Of Wernerius Mumai (Sissom, 1993) From Western Arizona, With Data On Reproduction (Scorpiones: Vaejovidae), Richard F. Ayrey, Brandon T. Myers

Euscorpius

A male of Wernerius mumai (Sissom, 1993) is described for the first time, collected at the type locality (Gold Road, Black Mountains, Mohave County, Arizona). Originally placed in the genus Vaejovis, this species later was transferred by Soleglad & Fet (2008) to the genus Wernerius. It is one of the smallest vaejovid species known. The pedipalp fixed finger usually has 6 ID denticles and the movable finger has 7. The most unique characteristic of this species is the long, pointed, subaculear tubercle.

Impact Of Dyrk1a Haploinsufficiency On Facial Morphology Using Three-Dimensional Morphometric Analysis, Stefani Hammond

The Pegasus Review: UCF Undergraduate Research Journal

Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A) is a gene present on human chromosome 21. Previous research suggests that this gene plays a developmental role in facial morphology. We hypothesize that individuals with DYRK1A haploinsufficiency have altered facial morphology with potentially unique patterns of facial variation. To assess this hypothesis, we acquired three-dimensional (3D) photogrammetric facial images of individuals with and without DYRK1A haploinsufficiency, and we measured anatomical landmarks to carry out Euclidean Distance Matrix Analysis (EDMA) and to evaluate global and local morphological differences. Our results show unique patterns of variation between individuals with DYRK1A haploinsufficiency and normal siblings, as …

2020-2021 Operating Budget, Southern University And A & M College. Office Of Finance & Administration.

All Southern University System Budgets

2020-2021 Operating Budget of Southern University Baton Rouge Campus.

Site Conditions Interact With Litter Quality To Affect Home-Field Advantage And Rhizosphere Effect Of Litter Decomposition In A Subtropical Wetland Ecosystem, Yingying Meng, Dafeng Hui, Chaohe Huangfu

Biology Faculty Research

The home-field advantage (HFA) hypothesis predicts that plant litter would decompose more quickly beneath its own plant species in the soil than beneath other plant species. Theoretically, HFA can be induced by the rhizosphere of growing plants, due to so-called rhizosphere effect (RE). Despite growing evidence for the site condition-dependence of both effects, few work has be conducted to explore how site climate, vegetation type and soil properties interact to affect RE and HFA, and especially limited in situ representation from subtropical wetland systems. In a field experiment, we reciprocally incubated three root litter species (Rumex dentatus L., Carex thunbergii …

Long Term Air Quality Analysis In Reference To Thermal Power Plants Using Satellite Data In Singrauli Region, India, H. K. Romana, Ramesh P. Singh, D. P. Shukla

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The exponentially growing population and related anthropogenic activities have led to modifications in local environment. The change in local environment, evolving pattern of land use, concentrations of greenhouse gases and aerosols alter the energy balance of our climate system. This alteration in climate is leading to pre-mature deaths worldwide. This study analyses the air quality of Singrauli region, Madhya Pradesh, India for the past 15 years. Otherwise known as Urjanchal “the energy capital” of India has been declared as critically polluted by CPCB. The study provides an updated list of thermal power plants in the study area and their emission …

2020-August-21-Pond Receives Honor, Bill Gatton College Of Pharmacy, East Tennessee State University, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY (Aug. 21, 2020) – East Tennessee State University bestowed its highest honors upon three professors today with the presentation of the 2020 Distinguished Faculty Awards for Teaching, Research and Service.

The winners were nominated and selected by their faculty peers. Each received a medallion, a plaque and $5,000 provided by the ETSU Foundation during the annual Faculty Convocation, which marks the beginning of the new academic year and fall semester. 

This year, the Faculty Convocation was delivered in a virtual format due to the COVID-19 pandemic. 

The Distinguished Faculty Award in Teaching was presented to Dr. Brooks Pond …

Cyclic Peptide-Gadolinium Nanoparticles For Enhanced Intracellular Delivery, Amir Nasrolahi Shirazi, Shang Eun Park, Shirin Rad, Luiza Baloyan, Dindyal Mandal, Muhammad Imran Sajid, Ryley Hall, Sandeep Lohan, Khalid Zoghebi, Keykavous Parang, Rakesh Tiwari

Pharmacy Faculty Articles and Research

A cyclic peptide containing one cysteine and five alternating tryptophan and arginine amino acids [(WR)₅C] was synthesized using Fmoc/tBu solid-phase methodology. The ability of the synthesized cyclic peptide to produce gadolinium nanoparticles through an in situ one-pot mixing of an aqueous solution of GdCl₃ with [(WR)₅C] peptide solution was evaluated. Transmission electron microscopy showed the formed peptide-Gd nanoparticles in star-shape morphology with a size of ~250 nm. Flow cytometry investigation showed that the cellular uptake of a cell-impermeable fluorescence-labeled phosphopeptide (F′-GpYEEI, where F′ = fluorescein) was approximately six times higher in the presence of [(WR) …

Cytokine Signature Of Inflammation Mediated By Autoreactive Th-Cells, In Calf Muscle Of Claudicating Patients With Fontaine Stage Ii Peripheral Artery Disease, George P. Casale, Johnathan R. Thompson, Lauren C. Carpenter, Julian Kyung-Soo Kim, Timothy J. Lackner, Constance Mietus, Duy M. Ha, Sara A. Myers, Katyarina E. Brunette, Shuai Li, Christina Shields, Gregory Wilcockson, Iraklis Pipinos

Journal Articles

Peripheral artery disease (PAD), a severe atherosclerotic condition primarily of the elderly, afflicts 200 million individuals, worldwide, and is associated with lower extremity myopathy. Circulating markers of inflammation have been linked to risk and severity of PAD but the contribution of local inflammation to myopathy remains unknown. We evaluated, by ELISA, calf muscle of PAD patients (N = 23) and control subjects (N = 18) for local expression of inflammatory cytokines including Granulocyte/Monocyte Colony-Stimulating Factor (GM-CSF), Interleukin 17A (IL-17A), Interferon ϒ (IFN-ϒ), tumor necrosis factor α (TNF-α), and Interleukin 6 (IL-6). One or more of these cytokines were expressed in …

Model And Data Concur And Explain The Coexistence Of Two Very Distinct Animal Behavioral Types, Jordi Moya-Laraño, Rubén Rabaneda-Bueno, Emily Morrison, Phillip H. Crowley

Biology Faculty Publications

Behaviors may enhance fitness in some situations while being detrimental in others. Linked behaviors (behavioral syndromes) may be central to understanding the maintenance of behavioral variability in natural populations. The spillover hypothesis of premating sexual cannibalism by females explains genetically determined female aggression towards both prey and males: growth to a larger size translates into higher fecundity, but at the risk of insufficient sperm acquisition. Here, we use an individual-based model to determine the ecological scenarios under which this spillover strategy is more likely to evolve over a strategy in which females attack approaching males only once the female has …

The Effect Of A Paired Lab On Course Completion And Grades In Nonmajors Introductory Biology, Dayna Jean Defeo, Andrew Bibler, Sarah Gerken

ISER Articles

This paper explores the effect of a paired lab course on students’ course outcomes in nonmajors introductory biology at the University of Alaska Anchorage. We compare course completion and final grades for 10,793 students (3736 who simultaneously enrolled in the lab and 7057 who did not). Unconditionally, students who self-select into the lab are more likely to complete the course and to earn a higher grade than students who do not. However, when we condition on observable course, academic, and demographic characteristics, we find much of this difference in student performance outcomes is attributable to selection bias, rather than an …

2020-August-21-Dr Brooks Pond Receives 2020 Distinguished Faculty Award For Teaching, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY (Aug. 21, 2020) – East Tennessee State University presented the 2020 Distinguished Faculty Award for Teaching to Dr. Brooks Pond, professor in the Department of Pharmaceutical Sciences.

The award was presented at the annual Faculty Convocation, which was delivered in a virtual format due to the COVID-19 pandemic.

Pond joined East Tennessee State University Bill Gatton College of Pharmacy as a founding faculty member in 2007. Over the past 13 years at ETSU, she has participated in didactic teaching of students within the College of Pharmacy and the biomedical science Ph.D. program.

Pond’s teaching accomplishments have …

Interleukin-6-Mediated Epigenetic Control Of The Vegfr2 Gene Induces Disorganized Angiogenesis In Human Breast Tumors, Mangala Hegde, Kanive Parashiva Guruprasad, Lingadakai Ramachandra, Kapaettu Satyamoorthy

Open Access archive

Disorganized vessels in the tumor vasculature lead to impaired perfusion, resulting in reduced accessibility to immune cells and chemotherapeutic drugs. In the breast tumor-stroma interplay, paracrine factors such as interleukin-6 (IL-6) often facilitate disordered angiogenesis. We show here that epigenetic mechanisms regulate the crosstalk between IL-6 and vascular endothelial growth factor receptor 2 (VEGFR2) signaling pathways in myoepithelial (CD101) and endothelial (CD311, CD1051, CD1461, and CD1332) cells isolated from malignant and nonmalignant tissues of clinically characterized human breast tumors. Tumor endothelial (Endo-T) cells in 3D cultures exhibited higher VEGFR2 expression levels, accelerated migration, invasion, and disorganized sprout formation in response …

The Role Of Machine Learning In Spine Surgery: The Future Is Now, Michael Chang, Jose A Canseco, Kristen Nicholson, Neil Patel, Alex R. Vaccaro

Department of Orthopaedic Surgery Faculty Papers

The recent influx of machine learning centered investigations in the spine surgery literature has led to increased enthusiasm as to the prospect of using artificial intelligence to create clinical decision support tools, optimize postoperative outcomes, and improve technologies used in the operating room. However, the methodology underlying machine learning in spine research is often overlooked as the subject matter is quite novel and may be foreign to practicing spine surgeons. Improper application of machine learning is a significant bioethics challenge, given the potential consequences of over- or underestimating the results of such studies for clinical decision-making processes. Proper peer review …

Ionophoric Polyphenols Are Permeable To The Blood Brain Barrier, Interact With Human Serum Albumin And Calf Thymus Dna, And Inhibit Ache Enzymatic Activity, Alberto Martinez, Mai Zahran, Miguel Gomez, Johnny Guevara, Rosemary Pichardo-Bueno, Junaid Asim, Gabriel Ortiz, Yaa Andoh, Sinji Shibutani, Baljit Kaur

Publications and Research

Alzheimer’s disease (AD) is the most common form of dementia that affects more than 40 million people around the world. The incidence is expected to rapidly increase due to the lack of any effective treatment. In previous work we synthesized a family of five ionophoric polyphenols (compounds 1–5) that targeted important aspects related to AD, such as the toxic aggregation of amyloid-β peptides, the production of reactive oxygen species, or the excessive presence of Cu²⁺ ions. Here, in order to gain insights into their potential therapeutic value, we have tested the ability of compounds 1– …

The Roles Of Host Species, Geographic Scale And Environmental Stressors In Shaping The Composition Of Coral Microbiomes, Alicia Marie Riegel Parker

LSU Doctoral Dissertations

Reef-building corals are long-lived and may take many centuries to adapt, making them especially susceptible to climate change. However, corals host microbial symbionts that can change quickly, potentially speeding acclimation. My dissertation aimed to determine the degree of coevolution and flexibility between corals and their microbiomes among hosts, across space, and in response to stress.

Microbial communities are usually surveyed by sequencing the 16S rRNA gene, however the PCR primers used also amplify coral DNA, thereby limiting prokaryotic read coverage. To mitigate this contamination, I designed a peptide nucleic acid clamp that increased the recovery of bacterial reads by 2-11x …

Defining The Relationship Between Maternal Care Behavior And Sensory Development In Wistar Rats: Auditory Periphery Development, Eye Opening And Brain Gene Expression, Jingyun Qiu, Preethi Singh, Geng Pan, Annalisa De Paolis, Frances A. Champagne, Jia Liu, Luis Cardoso, Adrián Rodríguez-Contreras

Advanced Science Research Center

Defining the relationship between maternal care, sensory development and brain gene expression in neonates is important to understand the impact of environmental challenges during sensitive periods in early life. In this study, we used a selection approach to test the hypothesis that variation in maternal licking and grooming (LG) during the first week of life influences sensory development in Wistar rat pups. We tracked the onset of the auditory brainstem response (ABR), the timing of eye opening (EO), middle ear development with micro-CT X-ray tomography, and used qRT-PCR to monitor changes in gene expression of the hypoxia-sensitive pathway and neurotrophin …

Dysregulation Of Ryr Calcium Channel Causes The Onset Of Mitochondrial Retrograde Signaling, Anindya Roy Chowdhury, Satish Srinivasan, György Csordás, György Hajnóczky, Narayan G Avadhani

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

This study shows that multiple modes of mitochondrial stress generated by partial mtDNA depletion or cytochrome c oxidase disruption cause ryanodine receptor channel (RyR) dysregulation, which instigates the release of Ca2+ in the cytoplasm of C2C12 myoblasts and HCT116 carcinoma cells. We also observed a reciprocal downregulation of IP3R channel activity and reduced mitochondrial uptake of Ca2+. Ryanodine, an RyR antagonist, abrogated the mitochondrial stress-mediated increase in [Ca2+]c and the entire downstream signaling cascades of mitochondrial retrograde signaling. Interestingly, ryanodine also inhibited mitochondrial stress-induced invasive behavior in mtDNA-depleted C2C12 cells and HCT116 carcinoma cells. In addition, co-immunoprecipitation shows reduced FKBP12 …

The Bach1/Nrf2 Axis In Brain In Down Syndrome And Transition To Alzheimer Disease-Like Neuropathology And Dementia, Marzia Perluigi, Antonella Tramutola, Sara Pagnotta, Eugenio Barone, D. Allan Butterfield

Chemistry Faculty Publications

Down syndrome (DS) is the most common genetic cause of intellectual disability that is associated with an increased risk to develop early-onset Alzheimer-like dementia (AD). The brain neuropathological features include alteration of redox homeostasis, mitochondrial deficits, inflammation, accumulation of both amyloid beta-peptide oligomers and senile plaques, as well as aggregated hyperphosphorylated tau protein-containing neurofibrillary tangles, among others. It is worth mentioning that some of the triplicated genes encoded are likely to cause increased oxidative stress (OS) conditions that are also associated with reduced cellular responses. Published studies from our laboratories propose that increased oxidative damage occurs early in life in …

Dosimetric Differences Between Cesium-131 And Iodine-125 Brachytherapy For The Treatment Of Resected Brain Metastases, Menachem Yondorf, Shahdabul Faraz, Andrew Smith, Albert Sabbas, Bhupesh Parashar, Theodore Schwartz, Gabriella Wernicke

Department of Radiation Oncology Faculty Papers

Purpose: To compare treatment plans and evaluate dosimetric characteristics of permanent cesium-131 (131Cs) vs. iodine-125 (125I) implants used in brain brachytherapy. Material and methods: Twenty-four patients with 131Cs implants from a prospective phase I/II trial were re-planned with 125I implants. In order to evaluate the volume of brain tissue exposed to radiation therapy (RT), the dose volume histogram was generated for both radioisotopes. To evaluate the dosimetric differences of the two radioisotopes we compared homogeneity (HI) and conformity indices (CI), and dose covering 100% (D100), 90% (D90), 80% (D80), and 50% (D50) of the clinical target volume (CTV). Results: At …

Structure And Mechanism Of A Unique Diiron Center In Mammalian Stearoyl-Coa Desaturase, Jiemin Shen, Gang Wu, Ah-Lim Tsai, Ming Zhou

Faculty, Staff and Students Publications

Stearoyl-CoA desaturase 1 (SCD1) is a membrane-embedded metalloenzyme that catalyzes formation of a double-bond on a saturated acyl-CoA. SCD1 has a diiron center and its proper function requires an electron transport chain composed of NADH (or NADPH), cytochrome b5 reductase (b5R), and cytochrome b5 (cyt b5). Since SCD1 is a key regulator in fat metabolism and is required for survival of cancer cells, there is intense interest in targeting SCD1 for various metabolic diseases and cancers. Crystal structures of human and mouse SCD1 were reported recently, however, both proteins have two zinc ions instead of two iron ions in the …

Constant Light Exposure Alters Gut Microbiota And Promotes The Progression Of Steatohepatitis In High Fat Diet Rats, Lin Wei, Fangzhi Yue, Lin Xing, Shanyu Wu, Ying Shi, Jinchen Li, Xingwei Xiang, Sin Man Lam, Guanghou Shui, Ryan D. Russell, Dongmei Zhang

Health & Human Performance Faculty Publications

Background: Non-alcoholic fatty liver disease (NAFLD) poses a significant health concern worldwide. With the progression of urbanization, light pollution may be a previously unrecognized risk factor for NAFLD/NASH development. However, the role of light pollution on NAFLD is insufficiently understood, and the underlying mechanism remains unclear. Interestingly, recent studies indicate the gut microbiota affects NAFLD/NASH development. Therefore, the present study explored effects of constant light exposure on NAFLD and its related microbiotic mechanisms.

Material and method: Twenty-eight SD male rats were divided into four groups (n=7 each): rats fed a normal chow diet, and exposed to standard light-dark cycle (ND-LD); …

The Peripheral Hearing And Central Auditory Processing Skills Of Individuals With Subjective Memory Complaints, Dona M.P. Jayakody, Holly K. Menegola, Jessica M. Yiannos, Jack Goodman-Simpson, Peter L. Friedland, Kevin Taddei, Simon M. Laws, Michael Weinborn, Ralph N. Martins, Hamid R. Sohrabi

Research outputs 2014 to 2021

© Copyright © 2020 Jayakody, Menegola, Yiannos, Goodman-Simpson, Friedland, Taddei, Laws, Weinborn, Martins and Sohrabi. Purpose: This study examined the central auditory processing (CAP) assessment results of adults between 45 and 85 years of age with probable pre-clinical Alzheimer’s disease – i.e., individuals with subjective memory complaints (SMCs) as compared to those who were not reporting significant levels of memory complaints (non-SMCs). It was hypothesized that the SMC group would perform significantly poorer on tests of central auditory skills compared to participants with non-SMCs (control group). Methods: A total of 95 participants were recruited from the larger Western Australia Memory …

Economic Analysis Of Vessel Sox Emission Reduction Measures In The Context Of China, Peng Guan

World Maritime University Dissertations

No abstract provided.