Digital Commons Network^™

The Anchor: September 2, 2020, Hope College

The Anchor: 2020

The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor's history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular.

Evidence For Height And Immune Function Trade-Offs Among Preadolescents In A High Pathogen Population, Angela R. Garcia, Aaron Blackwell, Benjamin C. Trumble, Jonathan Stieglitz, Hillard Kaplan, Michael Gurven

ESI Publications

Background

In an energy-limited environment, caloric investments in one characteristic should trade-off with investments in other characteristics. In high pathogen ecologies, biasing energy allocation towards immune function over growth would be predicted, given strong selective pressures against early-life mortality.

Methodology

In the present study, we use flow cytometry to examine trade-offs between adaptive immune function (T cell subsets, B cells), innate immune function (natural killer cells), adaptive to innate ratio and height-for-age z scores (HAZ) among young children (N = 344; aged 2 months–8 years) in the Bolivian Amazon, using maternal BMI and child weight-for-height z scores (WHZ) as …

Office Of Research, Economic Engagement And Outreach Update, September 2, 2020, Office Of Research, Economic Engagement And Outreach

Office of Research, Economic Engagement and Outreach

No abstract provided.

Mitochondrial Oxidative And Nitrosative Stress And Alzheimer Disease, D. Allan Butterfield, Debra Boyd-Kimball

Chemistry Faculty Publications

Oxidative and nitrosative stress are widely recognized as critical factors in the pathogenesis and progression of Alzheimer disease (AD) and its earlier stage, amnestic mild cognitive impairment (MCI). A major source of free radicals that lead to oxidative and nitrosative damage is mitochondria. This review paper discusses oxidative and nitrosative stress and markers thereof in the brain, along with redox proteomics, which are techniques that have been pioneered in the Butterfield laboratory. Selected biological alterations in—and oxidative and nitrosative modifications of—mitochondria in AD and MCI and systems of relevance thereof also are presented. The review article concludes with a section …

Caring For Aml Patients During The Covid-19 Crisis: An American And Italian Experience., Lindsay Wilde, Md, Alessandro Isidori, Gina Keiffer, Md, Neil D. Palmisiano, Md, Margaret Kasner

Department of Medical Oncology Faculty Papers

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the subsequent pandemic have impacted every aspect of oncology care worldwide. Healthcare systems have been forced to rapidly change practices in order to maximize the safety of patients and healthcare providers and preserve scare resources. Patients with acute myeloid leukemia are at increased risk of complications from SARS-CoV-2 not only due to immune compromise related to the malignancy but also due to the acuity of the disease and intensity of treatment. These issues have created unique challenges during this difficult time. In this article, we present the approaches taken …

Exploring The Eating Disorder Examination Questionnaire, Clinical Impairment Assessment, And Autism Quotient To Identify Eating Disorder Vulnerability: A Cluster Analysis, Natalia Stewart Rosenfield, Erik Linstead

Engineering Faculty Articles and Research

Eating disorders are very complicated and many factors play a role in their manifestation. Furthermore, due to the variability in diagnosis and symptoms, treatment for an eating disorder is unique to the individual. As a result, there are numerous assessment tools available, which range from brief survey questionnaires to in-depth interviews conducted by a professional. One of the many benefits to using machine learning is that it offers new insight into datasets that researchers may not previously have, particularly when compared to traditional statistical methods. The aim of this paper was to employ k-means clustering to explore the Eating Disorder …

A Simplified Quantitative Real-Time Pcr Assay For Monitoring Sars-Cov-2 Growth In Cell Culture, Christian Shema Mugisha, Hung R Vuong, Maritza Puray-Chavez, Adam L Bailey, Julie M Fox, Rita E Chen, Alex W Wessel, Jason M Scott, Houda H Harastani, Adrianus C M Boon, Haina Shin, Sebla B Kutluay

Open Access Publications

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions within just a few months, causing severe respiratory disease and mortality. Assays to monitor SARS-CoV-2 growth

Grit And Flow As Prescriptions For Self-Actualization, Samuel Dickinson

Journal of Wellness

Psychology as a discipline has historically focused on psychopathology and associated evidence-based modalities to alleviate symptoms of mental illness and distress. In recent decades, however, there has been a shift towards studying the positive aspects of human experience that make life worth living. This Positive Psychological perspective was utilized by Humanistic Psychologist Abraham Maslow when he created his theory of Self-Actualization, in which he postulated that the highest aim a person can strive towards is to become the absolute best version of themselves, and to maximize their abilities and potential to the highest possible degree. Aside from describing a hierarchy …

The Bg News September 02, 2020, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. September 02, 2020. Volume 100-Issue 3.

Modeling And Simulation For Target Tracking System Based On Dual-Pan-Tilt Camera, Kaishun Xiahou, Shanxing Chen, Yilin Wu

Journal of System Simulation

Abstract: Mathematical model of each component of target tracking system based on dual-pan-tilt camera was established. The rotation angles both in horizontal and vertical direction of each pan-tilt and the relative position of two cameras were adopted to estimate the real-time position of moving target with Extended Kalman Filter (EKF) tracking algorithm. A new real-time calibration method for pan-tilt camera was proposed to deal with the calibration problem that the external parameters of camera changes as the pan-tilt rotates in the process of camera modeling. In addition, the target’s image feature, extracted from the projected point on the camera image …

The Forgotten Students: Covid-19 Response For Youth And Young Adults Aging Out Of Foster Care, Mauriell H. Amechi

Educational Leadership & Workforce Development Faculty Publications

[First paragraph]

In March 2020, the coronavirus pandemic upended American higher education and shuttered campus doors across the country. As the opening vignette illustrates, many college students reported severe housing and food insecurities as a result. Nevertheless, not all college students experienced COVID-19’s effects and consequences equally. For example, Ivory, a current student enrolled at Concordia University Texas who spent 17 years in foster care, illuminated some of the difficulties she has personally faced in the wake of COVID-19. College students impacted by foster care make up approximately 5% of all undergraduates, and many are struggling to have their basic …

Mutagenic, Genotoxic And Immunomodulatory Effects Of Hydroxychloroquine And Chloroquine: A Review To Evaluate Its Potential To Use As A Prophylactic Drug Against Covid-19, Allan Giri, Ankita Das, Ajoy K. Sarkar, Ashok K. Giri

Student Publications

Hydroxychloroquine (HCQ) and Chloroquine (CQ) are two anti-malarial drugs that are now being extensively used by front-line healthcare workers and other common people as a prophylactic drug against the Corona Virus Disease - 19 (COVID-19) in India and as well as in many parts of the world. While only a few in vitro studies have pointed to some efficacy of these drugs as a prophylactic against COVID-19, to date, there are no clinical studies that have established any clinical efficacy of these drugs as a prophylactic. These drugs are commonly used for the treatment of Rheumatoid Arthritis (RA) and Systemic …

Glycomics: Immunoglobulin Gn-Glycosylation Associated With Mammary Gland Hyperplasia In Women, Zixiu Meng, Cancan Li, Guoyong Ding, Weijie Cao, Xizhu Xu, Yuanyuan Heng, Yang Deng, Yuejin Li, Xiaoyu Zhang, Dong Li, Wei Wang, Youxin Wang, Weijia Xing, Haifeng Hou

Research outputs 2014 to 2021

Mammary gland hyperplasia (MGH) is very common, especially among young and middle-aged women. New diagnostics and biomarkers for MGH are needed for rational clinical management and precision medicine. We report, in this study, new findings using a glycomics approach, with a focus on immunoglobulin G (IgG) N-glycosylation. A cross-sectional study was conducted in a community-based population sample in Beijing, China. A total of 387 participants 40-65 years of age were enrolled in this study, including 194 women with MGH (cases) and 193 women who had no MGH (controls). IgG N-glycans were characterized in the serum by ultra-performance liquid chromatography. The …

Managing Natural Grasslands In A Changing World: Grazing Ecology Insights To Accomplish Re‐Oriented Management Expectations, Paulo C. De F. Carvalho, Sila C. Da Silva, Carlos Nabinger, Anibal De Moraes, Teresa C. M. Genro

IGC Proceedings (1977-2023)

No abstract provided.

Long‐Term Soil Nitrogen And Carbon Change In Semi Steppe Rangelands Of Golestan National Park, Iran, Ramin Nourqolipour, Mohammad Jafary, M. Reza Bihamta

IGC Proceedings (1977-2023)

No abstract provided.

Identifying New Markers And Mechanisms Of Mitochondrial Defect During Aging, Catherine Chang

Natural Sciences and Mathematics | Biological Sciences Master's Theses

Mitochondrial dysfunction is a hallmark of aging and has been closely tied to age-related pathologies, such as cancer, cardiovascular diseases, neurodegenerative disorders, and metabolic syndromes. Though the consequences of mitochondrial defects are well documented, little is known about the molecular events that occur with age that transform healthy mitochondria into dysfunctional ones. Past studies have attempted to uncover the underlying proteomic changes in age, however, most of these results do not take into account population heterogeneity often associated with aging, thus highlighting the need for single-cell analysis. Technological barriers have impeded in-depth proteomic studies of aging mitochondria on a single …

Scientometric Analysis Of Publication Trend On Information Management (Im), C Baskaran -

Library Philosophy and Practice (e-journal)

The paper discusses the Research Pattern and Publications trend on Information Management (IM) during 2000-2019. The data will be taken to analyze by Web of Science (WoS) database from Clarivate analytics for purpose of study during period. It has analysed the highest 441 (9.04%) of the publications appeared in the year 2018, it followed by , 423( 8.67%) and 401(8.22%) of the publications have brought out in 2016 and 2017 respectively. Highest RGR observed that 1.277 and lowest 0.022 in 2019 and 2011 respectively. The majority 75.6 % of the publications appeared as Journal articles, it followed by 6.95% of …

A Glance Of P53 Functions In Brain Development, Neural Stem Cells, And Brain Cancer, Yuqing Xiong, Yun Zhang, Shunbin Xiong, Abie E. Williams-Villalobo

Faculty Publications

p53 is one of the most intensively studied tumor suppressors. It transcriptionally regulates a broad range of genes to modulate a series of cellular events, including DNA damage repair, cell cycle arrest, senescence, apoptosis, ferroptosis, autophagy, and metabolic remodeling, which are fundamental for both development and cancer. This review discusses the role of p53 in brain development, neural stem cell regulation and the mechanisms of inactivating p53 in gliomas. p53 null or p53 mutant mice show female biased exencephaly, potentially due to X chromosome inactivation failure and/or hormone-related gene expression. Oxidative cellular status, increased PI3K/Akt signaling, elevated ID1, and metabolism …

Identifying The Molecular Systems That Influence Cognitive Resilience To Alzheimer's Disease In Genetically Diverse Mice., Sarah E Heuer, Sarah M Neuner, Niran Hadad, Kristen M S O'Connell, Robert W Williams, Vivek M. Philip, Chris Gaiteri, Catherine Kaczorowski

Faculty Research 2020

Individual differences in cognitive decline during normal aging and Alzheimer's disease (AD) are common, but the molecular mechanisms underlying these distinct outcomes are not fully understood. We utilized a combination of genetic, molecular, and behavioral data from a mouse population designed to model human variation in cognitive outcomes to search for the molecular mechanisms behind this population-wide variation. Specifically, we used a systems genetics approach to relate gene expression to cognitive outcomes during AD and normal aging. Statistical causal-inference Bayesian modeling was used to model systematic genetic perturbations matched with cognitive data that identified astrocyte and microglia molecular networks as …

Term Matrix: A Novel Gene Ontology Annotation Quality Control System Based On Ontology Term Co-Annotation Patterns., Valerie Wood, Seth Carbon, Midori A Harris, Antonia Lock, Stacia R Engel, David P. Hill, Kimberly Van Auken, Helen Attrill, Marc Feuermann, Pascale Gaudet, Ruth C Lovering, Sylvain Poux, Kim M Rutherford, Christopher J Mungall

Faculty Research 2020

Biological processes are accomplished by the coordinated action of gene products. Gene products often participate in multiple processes, and can therefore be annotated to multiple Gene Ontology (GO) terms. Nevertheless, processes that are functionally, temporally and/or spatially distant may have few gene products in common, and co-annotation to unrelated processes probably reflects errors in literature curation, ontology structure or automated annotation pipelines. We have developed an annotation quality control workflow that uses rules based on mutually exclusive processes to detect annotation errors, based on and validated by case studies including the three we present here: fission yeast protein-coding gene annotations …

Student Handbook 2020-2021, Wofford College. Office Of Campus Life And Student Development

Student Handbooks

No abstract provided.

Wofford College Catalogue 2020-2021, Wofford College. Office Of The Registrar

College Catalogues

No abstract provided.

Interview Transcripts For Lin 200 "Language In The Us”, Mark Aronoff, Lori Repetti

Open Educational Resources

Language in the US (LIN 200), the most popular Linguistics course with nearly 800 students enrolling annually, is taught online every semester. A hallmark of the course is the large number of videos that we have created based on interviews that we conducted with leading experts in the field from around the world. We carefully edited the transcripts of these videos and use the transcripts as a text to accompany the course.

Is Diversity Possible In An Integrative Psychology? Transpersonal As A Whole Person / All Person Approach, Glenn Hartelius

International Journal of Transpersonal Studies Advance Publication Archive

No abstract provided.

Wofford Today Fall 2020, Wofford College. Office Of Marketing And Communications

Wofford Today

No abstract provided.

Guide Lines Vol. Ii, Issue 6 - September 2020, College Of Health And Human Services

GUIDE Lines

Periodic Newsletter of the Governors State University - University of Illinois, Chicago - Disparities Education Cancer research training and education project (The GUIDE Project).

"Identification And Characterization Of Genetic Determinants In Bacteria Involved In Froth Formation At Natural Water Bodies", Swathi A

Manipal Institute of Technology, Manipal Theses and Dissertations

Industrialization, modernization, rapid urbanization, and unscientific disposal of inadequately treated sewage and effluent from the various source into surface water bodies has been a major concern leading to water pollution. Frothing of lakes and foam related issues is one such emerging environmental concern in South India. Although several researchers have dealt with the characterization of physical and chemical parameters to understand the mechanism of foam formation, the role of biotic factors has been largely ignored. The main objective of this project is to identify the bacteria present in the froth forming lakes, to identify and characterize the biosurfactant of the …

Tability Studies On Ciclopirox Olamine Encapsulated Niosomes, Ganesh G. Keshavshet, Sidramappa B. Shirsand

Manipal Journal of Pharmaceutical Sciences

No abstract provided.

Development Trends Of Health Capital In Uzbekistan: Problems And Realities, G.U. Shamiev

Economics and Innovative Technologies

The article presents the issues of health capital formation as a component of human capital, analyzed the trends of its development, identified its main features, as well as the factors which influencing to its formation. Analyzed the main indicators which are reflecting to the health capital in Uzbekistan. Based on the analysis of qualitative and quantitative parameters, a conclusion was made on the formation of health capital, which will contribute to the further economic development of the country.

Information And Communication Technologies As A Factor Of Woman Employment, G.B. Urazalieva, G.A. Khudayberdieva

Economics and Innovative Technologies

The article analyses the current state of ensuring gender equality and the development of information and communication technologies in Uzbekistan. There are given outline of the state strategy in these issues and the main achievements. The authors highlight the interdependence of the success of the ongoing economic reforms on the solution of gender problems. It is noted that the Internet has changed the nature of communication in society, including between men and women. The introduction of modern ICT achievements into wide practice ensures the expansion of the horizons of human communication and the emergence of new opportunities for economic employment. …