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Factors Related To Maternal Adverse Outcomes In Pregnant Women With Cardiac Disease In Low-Resource Settings, Philippe Amubuomombe Poli, Elkanah Omenge, Ann Mwangi, Felix Ayub Barasa

Obstetrics and Gynaecology, East Africa

Background: Cardiac disease is an important life-threatening complication during pregnancy. It is frequently seen in pregnant women living in resource-limited areas and often results in premature death.

Aim: The aim of this hospital-based longitudinal study was to identify factors related to adverse maternal and neonatal outcomes in pregnant women with cardiac disease in low-resource settings.

Methods: The study enrolled 91 pregnant women with congenital or acquired cardiac disease over a period of 2 years in Kenya.

Results: Maternal and early neonatal deaths occurred in 12.2% and 12.6% of cases, respectively. The risk of adverse outcomes was significantly …

Alfred Russel Wallace Notes 12: How Good Was Wallace's Memory?, Charles H. Smith

Faculty/Staff Personal Papers

Alfred Russel Wallace (1823−1913) continues to be criticized for inconsistencies in his recollections of the earlier events in his life. This criticism, while not entirely unjust, has nevertheless been overplayed. Critics have not attended to the general understanding that self-biography is under the influence of two aspects of memory: that pertaining to remembrance of the qualities of past situations, and a secondary ability to assign absolutes of name or date to such memories. All evidence suggests that Wallace’s memory in the first sense was excellent throughout his life, but that he was prone to lapses of the second type.

Alfred Russel Wallace Notes 13: Wallace On Prayer, Charles H. Smith

Faculty/Staff Personal Papers

Alfred Russel Wallace (1823−1913) is known to most for his natural history explorations and theoretical biology, but he also developed thoughts on a number of subjects relatable to a wider appreciation of evolutionary cosmology. His adoption of spiritualism, for one, was attuned to this mission, and in turn his otherwise difficult-to-interpret two-sided position on prayer.

Characterizing Prenatal Maternal Distress With Unique Prenatal Cortisol Trajectories, Gage Peterson, Emma V. Espel, Elyssia Poggi Davis, Curt A. Sandman, Laura M. Glynn

Psychology Faculty Articles and Research

Objective: It is widely assumed that glucocorticoids represent a primary mechanism through which exposure to adversity and maternal psychological distress shape prenatal developmental trajectories of both mother and fetus. However, despite repeated investigations and the fact that prenatal cortisol has been reliably linked to developmental outcomes, the empirical evidence supporting an association between prenatal cortisol and maternal distress is scarce. In this study, a novel approach to assessing links between maternal prenatal psychological distress and gestational cortisol profiles, general growth mixture modeling (GGMM), was applied. Method: Measures of pregnancy anxiety, perceived stress, and state anxiety and depressive symptoms as well …

U.S. Settler Colonialism, White Supremacy, And The Racially Disparate Impacts Of Covid-19, Monika Batra Kashyap

Faculty Articles

This Essay contextualizes the racially disproportionate impacts of COVID-19 in the United States within a framework of settler colonialism in order to broaden the understanding of how structural inequality is produced, imposed, and maintained. A settler colonialism framework recognizes that the United States is a present-day settler colonial society whose laws, institutions and systems of governance continue to reenact the three processes upon which the United States was built—Indigenous elimination, anti-Black racism, and immigrant exploitation. This Essay connects these foundational processes—and their underlying White supremacist logics—to the disparate health impacts of COVID-19 on Indigenous, Black, and immigrant of color communities …

Chemical Effects Of Cold Atmospheric Plasma On Food Nutrients, Juan Manuel Pérez Andrés

Doctoral

A range of nonthermal techniques have demonstrated process efficacy in ensuring food product safety, extension of shelf-life and in general a retention of key quality attributes. However, various physical, chemical and biochemical effects of nonthermal techniques on both macro and micronutrients are evident, leading to both desirable and undesirable changes in food products. It is important to outline the effects of non-thermal techniques on food chemistry and the associated degradation mechanisms with the treatment of foods. Oxidation is one of the key mechanisms responsible for undesirable effects induced by non-thermal techniques. Degradation of key macromolecules largely depends on the processing …

Childhood Medulloblastoma, Naureen Mushtaq, Shahzadi Resham, Muhammad Shahzad Shamim, Bilal Mazhar Qureshi, Quratulain Riaz, Eric Bouffet

Section of Haematology/Oncology

Medulloblastoma is the most common malignant brain tumour in children and is a major cause of mortality and morbidity, particularly in low- and middle-income countries. It has been risk-stratified on the basis of clinical (age, metastasis and extent of resection) and histological subtypes (classic, desmoplastic and anaplastic). However, recently medulloblastoma has been sub-grouped by using a variety of different genomic approaches, such as gene expression profiling, micro-ribonucleic acid profiling and methylation array into 4 groups, namely Wingless, Sonic hedgehog, Group 3 and Group 4. This new sub-grouping has important therapeutic and prognostic implications. After acute leukaemia, brain tumour is the …

Numbers, Patrick Barry

Articles

Numbers can be numbing. Depend too much on them to make your case, pitch your product, or tell your story, and you risk losing your audience. This essay offers a way to way to use numbers—both large and small—in a manner that is at once more compelling and more concrete.

Recovery From Relinquishment: Forgiving My Birth Mother. My Journey From 1954 To Today, Christian L. Anderson

The Qualitative Report

Adoptees carry the burden of shame for being “given up, abandoned, unwanted, not right,” and birth mothers carry the weight of shame for succumbing to external pressure to relinquish their children. There is ample literature addressing recovery for both adoptees and birth mothers (Buterbaugh & Soll, 2003; Franklin, 2019; Lanier, 2020; Soll, 2005, 2013, 2014); however, there is little recognition of the co-shame and need for forgiveness. Utilizing autoethnographic methodology, I discuss the issues of misogyny prevalent in the 1950s, the “Baby Scoop Era [BSE],” and my ongoing process of forgiving my birth mother after five decades of rage. This …

Speciation‐By‐Depth On Coral Reefs: Sympatric Divergence With Gene Flow Or Cryptic Transient Isolation?, Carlos Prada, Michael E. Hellberg

Biological Sciences Faculty Publications

The distributions of many sister species in the sea overlap geographically but are partitioned along depth gradients. The genetic changes leading to depth segregation may evolve in geographic isolation as a prerequisite to coexistence or may emerge during primary divergence leading to new species. These alternatives can now be distinguished via the power endowed by the thousands of scorable loci provided by second‐generation sequence data. Here, we revisit the case of two depth‐segregated, genetically isolated ecotypes of the nominal Caribbean candelabrum coral Eunicea flexuosa. Previous analyses based on a handful of markers could not distinguish between models of genetic …

Implications Of Pneumonitis After Chemoradiation And Durvalumab For Locally Advanced Non-Small Cell Lung Cancer, Comron Hassanzadeh, Timothy Sita, Rohan Savoor, Pamela P Samson, Jeffrey Bradley, Michelle Gentile, Michael Roach, Nisha Mohindra, Saiama Waqar, Timothy J Kruser, Clifford Robinson

Open Access Publications

Background: Consolidation durvalumab improved overall survival (OS) in locally advanced non-small cell lung cancer (LA-NSCLC) treated with chemoradiotherapy (CRT) in the PACIFIC trial; however, pneumonitis was increased with durvalumab. We sought to examine real-world outcomes with the PACIFIC paradigm, especially factors associated with pneumonitis, using a multi-institutional review.

Methods: Patients with LA-NSCLC treated with CRT followed by durvalumab from January 2017-February 2019 were identified at 2 institutions. We characterized demographics, tumor factors, radiotherapy, and duration of durvalumab. We examined pneumonitis outcomes including re-challenge success, with secondary endpoints of progression-free survival (PFS) and OS.

Results: Thirty-four patients were included with median …

Editorial: Deep Carbon Science, Dawn Cardace, Dan J. Bower, Isabelle Daniel, Artur Ionescu, Sami Mikhail, Mattia Pistone, Sabin Zahirovic

Geosciences Faculty Publications

Our understanding of the slow, deep carbon cycle, key to Earth’s habitability is examined here. Because the carbon cycle links Earth’s reservoirs on nano- to mega-scales, we must integrate geological, physical, chemical, biological, and mathematical methods to understand objects and processes so small and yet so vast. Here, we profile current research in the physical chemistry of carbon in natural and model systems, processes ongoing in the deepest portions of planets, and observations of carbon utilization by the deep biosphere. The relationships between the carbon cycle and planetary habitability are undeniable, forming a conceptual anchor to all work in deep …

Effects Of Marathon Training On Male And Female Femoral Stress Fracture Risk, Clara Lin

Master's Theses

Marathon runners are prone to femoral stress fractures due to the high magnitudes and frequencies of lower extremity loads during training. Female runners tend to have a greater incidence of stress fracture compared to male runners. Sex-specific differences in body structure, joint pressure, and muscle activation patterns that influence bone remodeling may cause this observed difference in stress fracture occurrence. The goal of this thesis was to develop a finite element model of the femur during marathon training, then determine if marathon training affected bone properties of male and female runners differently. To achieve this goal, a finite element femur …

Apoe-Modified Liposomes Mediate The Antitumour Effect Of Survivin Promoter-Driven Hsvtk In Hepatocellular Carcinoma, Xiuli Mu, Xi Wang, Yan Wei, Chaochao Wen, Qi Zhang, Chunyang Xu, Chang Liu, Chan Zhang, Fanxiu Meng, Na Zhao, Tao Gong, Rui Guo, Gongqin Sun, Gaopeng Li, Hongwei Zhang, Qin Qin, Jun Xu, Xiushan Dong, Lumei Wang, Baofeng Yu

Cell and Molecular Biology Faculty Publications

Hepatocellular carcinoma (HCC) is a prevalent malignant tumour with high global morbidity and mortality associated with its multiple aetiologies, poor prognosis, resistance to chemotherapeutic drugs and high rate of recurrence. Here, we evaluated a gene therapy strategy that targets HCC using the herpes simplex virus thymidine kinase/ganciclovir (HSVtk/GCV) suicide gene system in HCC cell lines and in an in vivo human HCC xenograft mouse model. Apolipoprotein E (ApoE)-modified liposomes were used for targeted gene delivery to the tumour tissue, and the survivin promoter was used to drive HSVtk expression in HCC cells. Our results showed that the survivin promoter was …

Use Of Florpyrauxifen-Benzyl In Non-Flooded Rice Production Systems, Hannah Wright, Jason K. Norsworthy, Trenton L. Roberts, Robert C. Scott, Jarrod T. Hardke, Edward E. Gbur

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

The lack of a flood on rice (Oryza sativa) levees and in furrow-irrigated rice creates a favorable environment for terrestrial weeds like Palmer amaranth (Amaranthus palmeri S. Wats) to emerge and quickly overtake the crop for a longer portion of the year than in flooded rice culture. Florpyrauxifen-benzyl is a new auxin herbicide labeled for use in rice that has activity on both grasses and broadleaf weeds, as well as certain sedges. Field experiments were conducted to determine the efficacy of florpyrauxifen-benzyl in a non-flooded environment. Experiments were conducted in 2017 and 2018 at the Lon Mann …

Chinese International Students’ Narratives Of Their Experiences In A Graduate Pathway Program: An Exploratory Study, Lu Norstrand

USF Tampa Graduate Theses and Dissertations

Because of the tremendous growth of Chinese international students’ enrollment in American higher education and the rapid rise and development of Pathway programs in American universities, I determined the main purpose of this research was to determine the experiences of three Chinese international students in a Graduate Pathway program at a public four-year university in the Southeastern U.S. Three research questions were addressed:

1. How do three Chinese international students describe their academic experiences in a Graduate Pathway program in the U.S.?
2. How do these students describe differences in their learning experiences between the U.S. and China?
3. How do these students …

Extending The Functional Subnetwork Approach To A Generalized Linear Integrate-And-Fire Neuron Model, Nicholas Szczecinski, Roger Quinn, Alexander J. Hunt

Mechanical and Materials Engineering Faculty Publications and Presentations

Engineering neural networks to perform specific tasks often represents a monumental challenge in determining network architecture and parameter values. In this work, we extend our previously-developed method for tuning networks of non-spiking neurons, the “Functional subnetwork approach” (FSA), to the tuning of networks composed of spiking neurons. This extension enables the direct assembly and tuning of networks of spiking neurons and synapses based on the network’s intended function, without the use of global optimization ormachine learning. To extend the FSA, we show that the dynamics of a generalized linear integrate and fire (GLIF) neuronmodel have fundamental similarities to those of …

Variable Expression Of Msh6 In Endometrial Carcinomas With Intact Mismatch Repair And With Mlh1 Loss Due To Mlh1 Methylation, Nidhi Tandon, Courtney Hudgens, Bryan Fellman, Michael T Tetzlaff, Russell R Broaddus

Faculty, Staff and Student Publications

Immunohistochemistry for mismatch repair proteins MLH1, MSH2, MSH6, and PMS2 is an effective screen to detect individuals at risk for Lynch syndrome. College of American Pathologists guidelines stipulate that protein expression should be reported as present versus absent, as most patients with germline mutations in a mismatch repair gene have complete loss of protein expression in tumor cells. A similar approach is employed to screen for cancer patients eligible for immune checkpoint blockade. This "all or none" interpretive approach ignores substantial evidence that mismatch repair may be more finely regulated by other mechanisms. We have observed clinically that MSH6 expression …

Identification Of Novel Candidate Risk Genes For Myelomeningocele Within The Glucose Homeostasis/Oxidative Stress And Folate/One-Carbon Metabolism Networks, Paul Hillman, Craig Baker, Luke Hebert, Michael Brown, James Hixson, Allison Ashley-Koch, Alanna C Morrison, Hope Northrup, Kit Sing Au

Faculty, Staff and Student Publications

BACKGROUND: Neural tube defects (NTDs) are the second most common complex birth defect, yet, our understanding of the genetic contribution to their development remains incomplete. Two environmental factors associated with NTDs are Folate and One Carbon Metabolism (FOCM) and Glucose Homeostasis and Oxidative Stress (GHOS). Utilizing next-generation sequencing of a large patient cohort, we identify novel candidate genes in these two networks to provide insights into NTD mechanisms.

METHODS: Exome sequencing (ES) was performed in 511 patients, born with myelomeningocele, divided between European American and Mexican American ethnicities. Healthy control data from the Genome Aggregation database were ethnically matched and …

Growth Of Microalgae For Simultaneous Treatment Of Industrial Wastewater And Biodiesel Production, Mohammed Ahmad Tawfiq Abujayyab

Chemical and Petroleum Engineering Theses

The treatment of industrial wastewater contaminated with phenols is among the main challenges in the chemical, and particularly the petrochemical industry. Phenols, which present in considerable amounts in industrial wastewater, are toxic even at low concentrations. Therefore, it is essential to reduce their concentrations in water to harmless levels before being discharged. On the other hand, the dependence on the conventional fossil sources of energy, which is non-renewable, is not sustainable and can cause harmful environmental impacts. Therefore, in this work, the dual utilization of microalgae as a cheap and efficient means to remove phenolic compounds commonly found in refinery …

The Arabic Version Of The Personality Inventory For The Dsm-5 (Pid-5) In A Clinical Sample Of United Arab Emirates (Uae) Nationals, Olga Coelho, Rute Pires, Ana Sousa Ferreira, Bruno Gonçalves, Samia A. Alkhoori, Mohamed A. Sayed, Amany Elrasheed, Sara Belhoul, Maryam Aljassmi, Joana Stocker

All Works

Objectives: We aimed to test the potential of the Arabic version of the PID-5 to distinguish between clinical and non-clinical participants, as well as to examine its convergent validity and factor structure in an Emirati clinical sample. Methods: The Arabic version of the PID-5 was administered to a clinical sample comprised of 156 participants (Mage = 31.38, SD = 8.99, 37.8% male, 62.2% female) and a community sample also comprised of 156 participants (Mage = 31.43, SD = 9.52, 37.2% male, 62.8% female). We addressed the descriptive measures, internal consistency, mean rank scores differences, convergent validity with SCL-90-R, and PID-5's …

Investigating Early Childhood Educators’ Experiences In Teaching Phonological Awareness: A Case Study, Kristine Reilly

All Theses And Dissertations

Literacy instruction, or teaching educators how to teach reading, is increasingly important as the effects of illiteracy impact everyone from the individual level to the societal level. The cost of illiteracy to the global economy is estimated at $1.2 trillion U.S. dollars (World Literacy Foundation, 2015). Improving literacy for all becomes a social justice concern as access to literacy opens avenues to further education and to improved physical and mental wellbeing. Over the past forty years, neurocognitive and behavioral science has demonstrated how the human brain learns to read. However, educator training programs and professional development have not kept pace …

My Music Time: Emotional Well-Being Through Musical Play, Johannes Dreyer

Postgraduate

Music is a ubiquitous feature of everyday life; we soundtrack a range of activities from mundane tasks like shopping through to significant events like our wedding day. We have a deeply emotional connection to music across cultures, and music is highly influential in shaping emotions. Interacting with music has also shown to have excellent health and wellness benefits to participants and consumers alike.

This creative practice exegesis explores interactive music-making and, specifically, designing an interactive online application that aims to assist with emotional regulation and recognition while measuring how participants interacted with the application. Of particular interest was whether school-aged …

Identification Of Inherited And De Novo Exomic Variations In An Emirati Family With Neurodevelopmental Disorders, Asmaa Samir Muhammed Abdelaziz Refaey

Biology Theses

Neurodevelopmental disorders (NDDs) are a heterogenous group of disorders that affect children at any point of development and lead to mental and motor function deficits. Often, the underlying cause could be genetic and inherited. This study investigated possible genetic variations that could have led to these neurological abnormalities and other genetic disorders in an Emirati family. Whole exome sequencing (WES) was used to sequence the protein-coding regions of the genome to identify potential de novo and inherited variants that are associated with disorders in this family.

WES of DNA from the parents and ten children were performed. Several variants were …

In Conversation With Fatimah Jackson: The Life And Career Of An African American Muslim Biological Anthropologist, Fatimah Jackson, Sameena A. Mulla

Social and Cultural Sciences Faculty Research and Publications

As an important voice in genetic and molecular anthropology, Fatimah Jackson has challenged race science and modeled ethical, methodological, and analytical responsibility in relation to the role of race and exclusion in anthropology. She has published innovative research on ecology, plant–human–animal interactions, health, and disease, particularly in her commitment to studying malaria and its abatement. In this conversation, Jackson shares her frank assessments of the racism and sexism she has faced. Current events and day-to-day life shaped her outlook and cultivated her curiosities, as did her involvement in key scientific achievements, such as the Human Genome and Human Genome Diversity …

Maternal Altitude And Risk Of Low Birthweight: A Systematic Review And Meta-Analyses, Lin Yang, Veronika Helbich-Poschacher, Chao Cao, Katrin Klebermass-Schrehof, Thomas Waldhoer

2020-Current year OA Pubs

BACKGROUND: Previous studies conducted in high altitude regions showed that maternal altitude was associated with low birth weight. The effect size of birth weight reduction is inclusive with unknown effects due to preterm birth. We systematically reviewed the literature and synthesize evidence on associations between altitude elevation from sea level and birth weight.

METHOD: We searched MEDLINE/PubMed, Embase, Scopus, Web of Science, and Cochrane database, from inception to May 5, 2020 for studies that reported maternal altitude and birth weight. Bayesian multilevel effect models were employed to estimate the effect size on birth weight (and gestational age) associated with altitude. …

Hyperspectral Properties Of Date Palm Trees (Phoenix Dactylifera L.), Mohamed Ali Saeed Ahmed Al Abdouli

Theses

The goal of this study is to classify the Date Palm varieties based on hyperspectral signature technology since it is difficult to identify the Date Palm cultivars without fruits. It will also help to obtain the hyperspectral signature for different types of date palm trees. Moreover, it also assists to determine the wavelength fingerprint of each cultivar and to recommend the best classification protocol differentiating among different cultivars based on spectral signature. Utilizing the Hyperspectral imaging technology precisely on the leaves of different Date Palm cultivars, thus facilitating identification of date palm cultivars without the fruits and make the spatial …

Estimation Of The Removal Of Chiral Pharmaceutical Drugs From Domestic Wastewater Using Uplc-Ms/Ms, Mohammed Khaled Al Tabaji

Theses

This thesis is concerned with the estimation of the removal of chiral pharmaceutical compounds (PCs) from domestic wastewater in Al Ain using UPLC-MS/MS. PCs are classified into many classes such as hormones, antibiotics, analgesics, cosmetic products, ꞵ blockers, and anti-inflammatory drugs. PCs do not have a guideline to describe their concentrations in treated domestic wastewater. Additionally, there is a very high demand for using PCs around the world, which results in their discharge to wastewater at relatively high masses, which could be harmful to the environment. Furthermore, very limited work has been done to estimate the removal of chiral PCs. …

A New Green Composite Based On Polylactic Acid Mixed With Biomass From Uae Date Palm Waste For Cutlery And Food Packaging Applications, Noran Hussein Awad Elsayed Mousa

Theses

Petroleum-based plastic cutlery is widely used and due to its non-biodegradable properties, they cause serious threats to the environment. Therefore, there is a need to fabricate such products from biodegradable material. Date Palm Rachis (DPR) waste was used as a filler in three levels of 30 wt%, 40 wt% and 50 wt% for cost-performance optimization balance and to improve the thermal behaviours of the biodegradable Polylactic Acid (PLA). The preparation of biodegradable PLA/date palm waste composites was done using a melt mixing extruder at 180°C by varying parameters such as mixing time, the composition of date palm waste biomass, biomass …

Green Synthesis, Characterization, Antioxidant And Anticancer Activities Of Silver Nanoparticle Using Moringa Peregrina Leaf Extract, Khaled Saeed Al Baloushi

Theses

The sustainable green synthesis process for the development of environment-friendly, toxicant-free and biocompatible nanoparticles establishes important aspects in nanotechnology research. Even though; nanoparticles can be produced by either conventional physical and chemical or green synthesis, synthesizing nanoparticles using plant extracts as reducing and capping agents is acceptable. The benefits of plant extract mediated synthesis of silver nanoparticles comprise economic viability, quick synthesis, toxicity free, cost-effectiveness and large scale synthesis. In that way, the aqueous extract of Moringa peregrina leaves was used to synthesizes silver nanoparticles. The silver nanoparticles were characterized by various spectral studies including FT-IR, SEM, HR-TEM and XRD. …