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Genetic Variation And Sex Mediate Differential Responses To ∆-9-Tetrahydrocannabinol Among Inbred Mice, Cory Parks

Theses and Dissertations (ETD)

The plant Cannabis sativa has been used by people for both recreational and medicinal use for thousands of years, but scientific investigation of the plant and its components didn’t begin until the early nineteen hundreds when Cannabis components known as phytocannabinoids were characterized and later isolated. In the 1970’s, ∆9-tetrahydrocannabinol (THC) was isolated and recognized as the major constituent responsible for the psychoactive and intoxicating effects associated with consumption of cannabis. This opened the door for intensive research in the field that lead to the discovery of the endogenous cannabinoid system and its associated receptors, effectors of signaling, and biosynthetic …

Strain And Stress Relationships For Optical Phonon Modes In Monoclinic Crystals With Β-Ga2O3 As An Example, Rafal Korlacki, Megan Stokey, Alyssa Lynn Mock, Sean Knight, Alexis Papamichail, Vanya Darakchieva, Mathias Schubert

Department of Electrical and Computer Engineering: Faculty Publications

Strain-stress relationships for physical properties are of interest for heteroepitaxial material systems, where strain and stress are inherent due to thermal expansion and lattice mismatch. We report linear perturbation theory strain and stress relationships for optical phonon modes in monoclinic crystals for strain and stress situations which maintain the monoclinic symmetry of the crystal. By using symmetry group analysis and phonon frequencies obtained under various deformation scenarios from density-functional perturbation theory calculations on β-Ga₂O₃, we obtain four strain and four stress potential parameters for each phonon mode. We demonstrate that these parameters are sufficient to …

Exploring A Novel Substrate-Borne Vibratory Signal In The Wolf Spider Schizocosa Floridana, Malcolm F. Rosenthal, Eileen Hebets, Rowan H. Mcginley, Cody Raiza, James Starrett, Lin Yan, Damian O. Elias

Eileen Hebets Publications

Animals communicate using a diversity of signals produced by a wide array of physical structures. Determining how a signal is produced provides key insights into signal evolution. Here, we examine a complex vibratory mating display produced by male Schizocosa floridana wolf spiders. This display contains three discrete substrate-borne acoustic components (known as “thumps”, “taps”, and “chirps”), each of which is anecdotally associated with the movement of a different body part (the pedipalps, legs, and abdomen respectively). In order to determine the method of production, we employ a combination of high-speed video/audio recordings and SEM imaging of possible sound-producing structures. Previous …

Testing The Hypothesized Antipredator Defence Function Of Stridulation In The Spiny Orb-Weaving Spider, Micrathena Gracilis, Tyler B. Corey, Eileen A. Hebets

Eileen Hebets Publications

The observable diversity of antipredator defenses across organisms demonstrates predation’s impact on trait evolution. The functions of many traits that are presumed to have an antipredator function have never been directly tested. The spiny orb-weaving spider, Micrathena gracilis, for example, stridulates when grasped. While stridulation was first hypothesized to be an antipredator defense nearly 50 years ago, no data exist to support this hypothesis. To explore the form and function of M. gracilis stridulation, we first quantified the behavioral and acoustical properties of sound production. Next, using laboratory assays, we directly tested the effect of stridulation on survival with …

Photodissociation Of Aqueous I 3 - Observed With Liquid-Phase Ultrafast Mega-Electron-Volt Electron Diffraction, K. Ledbetter, E. Biasin, J. P.F. Nunes, Martin Centurion, K. J. Gaffney, M. Kozina, M. F. Lin, X. Shen, J. Yang, X. J. Wang, T. J. A. Wolf, A. A. Cordones

Martin Centurion Publications

Developing femtosecond resolution methods for directly observing structural dynamics is critical to understanding complex photochemical reaction mechanisms in solution. We have used two recent developments, ultrafast mega-electron-volt electron sources and vacuum compatible sub-micron thick liquid sheet jets, to enable liquid-phase ultrafast electron diffraction (LUED). We have demonstrated the viability of LUED by investigating the photodissociation of tri-iodide initiated with a 400 nm laser pulse. This has enabled the average speed of the bond expansion to be measured during the first 750 fs of dissociation and the geminate recombination to be directly captured on the picosecond time scale.

Toward The Standardization Of Mesoscale Meteorological Networks, Christopher Fiebrich, Kevin Brinson, Rezaul Mahmood, Stuart Foster, Megan Schargorodski, Nathan L. Edwards, Christopher A. Redmond, Jennie R. Atkins, Jeffrey Andresen, Xiaomao Lin

School of Natural Resources: Faculty Publications

Although they share many common qualities in design and operation, mesonetworks across the United States were established independently and organically over the last several decades. In numerous instances, the unique ways each network matured and developed new protocols has led to important lessons learned. These experiences have been shared in informal ways among various network operators over the years to promote reliable operation. As existing networks begin to introduce new sensors and technologies, and as new networks come online, there is a common need for guidance on best practices. This paper aims to formally provide recommendations to improve and harmonize …

Assessment Of Research Productivity Of Indian School Of Business (Isb), Hyderabad, India, Ramesh Kuri, Kunwar Singh, Madan Singh, Somanagouda Patil

Library Philosophy and Practice (e-journal)

This study aimed to perform a scientometric analysis of the Indian School of Business, Hyderabad, from 2002 to 2020. The study has used different scientometric dimensions to evaluate the quantitative growth of research publications. The affiliation search was performed to find out the research publications by using the Scopus database. To make the analysis complete and to get better outcomes, authors have considered total publications produced since the inception of ISB, Hyderabad. This study has analysed the year-wise growth of publications, most preferred sources, authorship pattern, subject-wise distribution of papers, etc. Furthermore, the study also explored international research collaboration. During …

The Emergence Of New Trends In Clinical Laboratory Diagnosis, Mohammed A. Alaidarous

Saudi Medical Journal

Diagnostic processes typically rely on traditional and laborious methods, that are prone to human error, resulting in frequent misdiagnosis of diseases. Computational approaches are being increasingly used for more precise diagnosis of the clinical pathology, diagnosis of genetic and microbial diseases, and analysis of clinical chemistry data. These approaches are progressively used for improving the reliability of testing, resulting in reduced diagnostic errors. Artificial intelligence (AI)-based computational approaches mostly rely on training sets obtained from patient data stored in clinical databases. However, the use of AI is associated with several ethical issues, including patient privacy and data ownership. The capacity …

In Vitro Invistigation Of The Heterodimerization Between Angiotensin Ii And Thrombin Receptors, Isra Mansur Al Zamel

Biology Theses

The renin angiotensin system (RAS) through its hormone angiotensin (AngII) and the protease thrombin are two major physiological regulators of vascular and renal functions. RAS is involved in the regulation of blood pressure and water-electrolytes hemostasis, while thrombin has a crucial role in platelets activation and thrombosis. The interplay between these two systems at the physiological and the pathophysiological levels has been documented in many studies. However, such an interplay at the pharmacological level between the AngII and thrombin receptors still has not been explored. Our study aimed to explore the interplay between the AngII type 1 receptor (AT1R) and …

Molecular And Physiological Assessment Of Salinity Stress Tolerance In Transgenic Arabidopsis Lines Expressing A Solanum Tuberosum Ribosome-Binding Protein, Onoud Rashed Saeed Ali Alyammahi

Biology Theses

Ribosomal proteins are highly conserved components of basal cellular organelles, primarily associated with translation of mRNA leading to protein synthesis. Additionally, some of these proteins are known to play critical role in plants RNA metabolism during stress responses, growth, and development. In this study, transgenic Arabidopsis plants expressing a ribosomal protein S27 (hereafter D26) isolated from Solanum tuberosum was subjected to NaCl-induced salinity stress conditions, to evaluate their putative stress resistance. Transgenic plants were exposed to high salinity stress, induced by 200 mM NaCl and physiological and biochemical assays were performed. The D26 transgenic plants demonstrated improved plant height and …

Floristic Changes In The Understory Vegetation Of Mixed Temperate New England Freshwater Island Forests Over A Period Of 33 Years, Marjorie M. Holland, Mark Winkler

Faculty and Student Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. During a 33-year sampling period, we observed species richness and calculated species evenness and Shannon Diversity for understory woody seedlings and herbaceous species on three small islands in Lake Winnipesaukee, New Hampshire, and noted consistency of dominant plant species over time. Seedlings and herbaceous species were recorded and measured in 25 permanent plots that were created on the three islands in 1978. The understory species data were compiled by frequency and dominance of woody seedlings and herbaceous species. Data from 250 individual quadrats show that species richness more than doubled from …

Imágenes De Poslatinoamérica 2020, Saint Mary's College Of California

Imágenes de Poslatinoamérica

No abstract provided.

The Prospector, November 25, 2020, Utep Student Publications

The Prospector

Headline: Another Graduation Lost to COVID-19

Graduation issue. Contains a list of the 2020 graduates.

The Efficacy Of Using Scb Guidelines To Facilitate Conservation Science-Faith Collaboration: Experiences In The Field, Jame Schaefer, Kit Magellan, Robert Sluka, Shekhar Kolipaka, Oscar Gonzalez, Akmal Arif Mohd Razali, Gopalasamy Reuben Clements, Chantal Elkin

Theology Faculty Research and Publications

Recognizing the need to identify ways in which conservation researchers and practitioners can work constructively with faith leaders and communities to conserve biological diversity, the Religion and Conservation Biology Working Group of the Society for Conservation Biology formally launched the Best Practices Project in March 2016 for the purpose of collecting recommendations from SCB members throughout the world. A survey of members in 2016, a forum at the 2016 International Marine Conservation Congress in Newfoundland/Labrador, a symposium, workshop and poster session at the 2017 International Congress for Conservation Biology in Colombia, and an e-mail request to RCBWG members in October …

J Mich Dent Assoc November 2020

The Journal of the Michigan Dental Association

Every month, The Journal of the Michigan Dental Association brings news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. No publication reaches more Michigan dentists!

In this issue, the reader will find the following original content:

• Feature articles on how “Routine Blood Lead Testing During Pregnancy Empowers Future Dental Caries and Neurotoxicity Research”, how to “Recoup Your Dues and More with MDA-Endorsed Programs”, and your “2021 MDA Membership Benefits Guide”.
• News you need, Editorial and regular department articles on MDA Foundation activities, Dentistry and the Law, Staff Matters, 10-Minute EBD, Headquarters …

Geneseo Authors Celebration 2020, Milne Library

Geneseo Authors Celebration

No abstract provided.

Modeling Age-Dependent Developmental Changes In The Expression Of Genes Involved In Citrulline Synthesis Using Pig Enteroids, Mahmoud A Mohammad, Inka C Didelija, Barbara Stoll, Douglas G Burrin, Juan C Marini

Children’s Nutrition Research Center Staff Publications

metabolism of citrulline and arginine are well characterized. Enteroids, a novel ex-vivo model that recreates the three-dimensional structure of the intestinal crypt-villus unit, have shown to replicate molecular and physiological profiles of the intestinal segment from where they originated ("location memory").

Objective: The present study tested the hypothesis that enteroids recapitulate the developmental changes observed in vivo regarding citrulline production in pigs ("developmental memory").

Methods: Preterm (10- and 5-d preterm) and term pigs at birth, together with 7- and 35-d-old pigs were studied. Gene expression was measured in jejunal samples and in enteroids derived from this segment. Whole body citrulline …

N Y State Dent J November 2020

The New York State Dental Journal

The New York State Dental Journal (NYSDJ) is produced by the New York State Dental Association (NYSDA) six times a year, in January, March, April, July, September and November. Each issue features clinical and scientific articles written by researchers and practitioners from around the globe and is subject to review by a panel of specialists convened by the Editor.

Issues include cover and feature articles alongside regular columns with regional news impacting the New York membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Evaluating Leadership Development Through Experiential Learning In A Virtual Environment, Paul J. Mckenney

All Theses And Dissertations

The strategic leadership center of a senior military service college collaborated with an elite law school to provide leadership development to senior law school students. The focus was an International Strategic Crisis Negotiation Exercise set in the South China Sea. Due to an unexpected global health pandemic the course was forced online to a virtual environment. The strategic leadership center gathered data from volunteer students and their mentors to determine the impact of the virtual setting. Using four archival datasets, a program evaluation was conducted using a case study methodology to determine the effectiveness of experiential learning through simulation in …

Evaluating The Solution Focused Wellness For Hiv Intervention For Women: A Pilot Study, Helen T. Yates, Orion Mowbray

Journal of Solution Focused Practices

Women living with HIV experience a gender gap in wellness outcomes in the U.S., and women of color are particularly vulnerable to this gap. To address this, the Solution Focused Wellness for HIV (SFWH) intervention for women was created. In this paper, we report the quantitative results of the most recent SFWH pilot study. The seven-session, group intervention was provided to (N=14) women living with HIV to evaluate it for effectiveness. Results showed the intervention was associated with significant multidimensional wellness improvements between baseline and five-week follow up. Participants’ CD4 and Viral Load counts did not change significantly. To improve …

Exploring The Role Of Ccp1 And Ccp2 In The Chlamydomonas Reinhardtii Carbon Dioxide Concentrating Mechanism, Lillian Laplace

Honors Capstones

No abstract provided.

Ribosomal Rna Synthesis After Induced Nucleolar Stress In Drosophila Melanogaster, Kyle Maher

Honors Capstones

No abstract provided.

Increasing The Bioavailability Of Poorly Soluble Anti-Cancer Prodrugs Through Encapsulation In Platinum Based Nanocages, Salim Cesar Lutfallah

Honors Capstones

No abstract provided.

A New Era: Utilizing Technology Tools To Enhance Elder Independence, April Lisa Phelps

Doctoral Dissertations and Projects

The goal of this integrative review was to examine the multitude of technology tools and the evidence which supports their use to enhance elders’ independence when residing at home. Multiple journal articles and books published between July 2015 and July 2020 were examined using the PRISMA model for evidence to support or oppose the use of technology to enhance the elders’s independence. A total of 27 articles were included in the final review. An exploration of gaps in knowledge related to the issue of elders using technology tools such as wearable sensors, artificial intelligence, home monitoring, robots, mHealth, Internet of …

Improving Teacher Retention In A South Carolina School District, Christine Proctor Gunter

Doctoral Dissertations and Projects

The purpose of this applied study is to solve the problem of the teacher retention issue for a school district in South Carolina and to design a solution to address the problem. A multi-method design was used consisting of both qualitative and quantitative approaches. The first approach was structured interviews with administrators. The interviews with administrators aimed to set the foundation on their school’s teacher retention and attrition and provided an outline for supportive opportunities they offer early-career teachers. Surveys with early-career teachers provided insight to their thoughts and feelings about their profession and school. The third approach is to …

A Mixed Methods Study Concerning Biblical Worldview Formation In Children And Adolescents Through Informal Learning By Parents And/Or Guardians, Joan Ellen Appleton

Doctoral Dissertations and Projects

Children and adolescents need spiritual nurturing and teaching to instill biblical worldview and to make possible the development of lifelong spiritual formation. Informal learning as an educational format is foundational to and provides an avenue by which to impart early biblical worldview formation for children and adolescents. The purpose of this explanatory sequential mixed methods study was to examine and explore the knowledge and behaviors of informal learning of the study participants (parents and/or legal guardians) in five U.S. Southeast states to determine the relationship between informal learning and outcomes of biblical worldview formation in children and adolescents. The mixed …

Women Who Endured Childhood Maltreatment: How Resiliency Led To Lower Mental Health Issues, Rebecca Lee Hirshman

Doctoral Dissertations and Projects

The purpose of this study was to have a better understanding of the positive impact that resiliency has on an individual that has endured childhood maltreatment. This qualitative study focused on the information gathered from seven women ranging in age from 18 to 60 years old. Each participant answered three questionnaires (the Adverse Childhood Experience, Brief Resilience Coping Scale, and a Survey Questionnaire) prior to participating in a Zoom interview. This study elaborated on the four types of childhood maltreatment, what prompted the need for programs and interventions, the detrimental effects it has on the development of children and their …

Effectiveness Of Treatment Modalities For Those With Diagnosed Opioid Use Disorder And Co-Occurring Disorders, Amy Parousis

Doctoral Dissertations and Projects

Substance abuse has always been an issue in society. As time has passed, the adverse consequences of substance abuse have become more evident. These consequences include physical and mental addiction, disruption of purposeful and productive everyday life, disruption of the family unit, spread of diseases, and death. Recently, the rate of overdose has rapidly increased due to the potency and accessibility of illicit opiates. Fentanyl and carfentanyl have been added to many opioid and non-opioid substances to provide a more euphoric experience, to intensify the addiction of the client, and for economic reasons because they are much more potent than …

Characterizing Drosophila Melanogaster Sleep Models Using An Optogenetic Engineered Caspase And Channelrhodopsins, Corey Cooper

Honors Capstones

No abstract provided.

Wnt Signaling Determines Body Axis Polarity In Regenerating Hydra Tissue Fragments, R. Wang, R. E. Steele, Eva-Maria S. Collins

Biology Faculty Works

How an animal establishes its body axis is a fundamental question in developmental biology. The freshwater cnidarian Hydra is an attractive model for studying axis formation because it is radially symmetric, with a single oral-aboral axis. It was recently proposed that the orientation of the new body axis in a regenerating Hydra polyp is determined by the oral-aboral orientation of the actin-myosin contractile processes (myonemes) in the animal’s outer epithelial layer. However, it remained unclear how the oral-aboral polarity of the body axis would be defined. As Wnt signaling is known to control axis polarity in Hydra and bilaterians, we …