Digital Commons Network^™

Technology Progress Of Sand Industry Based On Desertification Control Engineering By Revegetation: Case Study On Cistanche Plantation, Fan Jinglong, Li Bingwen, Xu Xinwen, Li Shengyu

Bulletin of Chinese Academy of Sciences (Chinese Version)

The connotation of "sand industry" is to utilize the desert resources in the process of prevention and control of desertification effectively, and expand the space of energy-saving green agricultural industry. This paper overviews the technological advances about Cistanche deserticola planting industry, introduces the development trend of Cistanche deserticola industry and advanced planting technology especially, analyzes and estimates economic benefits of Cistanche deserticola planting, finally, views the application and popularization perspective of Cistanche deserticola planting technologically.

Accelerating Construction Of Innovative Country To Promote Modernization Of China's Emergency Supplies Reserve System, Sun Yi, Wu Jing, Liu Changxin, Zhu Yongbin

Bulletin of Chinese Academy of Sciences (Chinese Version)

The outbreak of novel coronavirus pneumonia exposed the shortcomings of China's public health emergency management system, and accelerated the reform of all related businesses. The reform of emergency supplies reserve is imminent. This work reviews the development process of China's main material reserve system, studies the international experience of material reserve system construction, analyzes the main problems existing in China's current emergency material reserve system, and defines the overall goal of reform: to establish and improve the laws and regulations system in the field of national emergency material reserve; to form a modern comprehensive leadership and management capacity of material …

Transgender Labour Market Outcomes: Evidence From The Us, Klavs Ciprikis, Damien Cassells, Jenny Berrill

Articles

Alternative labour market outcomes for men and women have been studied extensively in past literature. However, existing studies fail to directly compare labour market differences between transgender and non-transgender people. We utilize data from the 2015 Behavioral Risk Factor Surveillance Sys- tem in the United States to examine employment and wage differentials between transgender persons and non- transgender people using the Fairlie decomposition method of 2005. Our findings suggest that transgender people are less likely than non-transgender people to be employed, and are more likely than non-transgender people to receive lower wages. While some of the difference in employment and …

Occurrence Of North American Porcupine (Erethizon Dorsatum) In The Black Hills, South Dakota, Lenora M. Dombro, Earl Perez-Foust, Daniel Roddy, Daryl E. Mergen, Robert A. Gitzen

Western North American Naturalist

During the twentieth century, the North American porcupine (Erethizon dorsatum) was common in the Black Hills of western South Dakota and northeastern Wyoming. However, the low number of recent observations in the region has led to concern that porcupine populations have declined. We conducted systematic surveys to assess porcupine occurrence at two hundred and sixty-three 1-ha sites in the Black Hills National Forest, Custer State Park, Jewel Cave National Monument, Mount Rushmore National Memorial, and Wind Cave National Park during 2016–2017. We observed no porcupines or recent feeding sign. We also noted few recent observations in information compiled …

Educated To Death? Women’S Higher Education, Reproductive Health, And The Scientific Method In The United States, 1870-1900, Eleanor Naiman

Swarthmore Undergraduate History Journal

From 1870-1890, American gynecologists positioned themselves at the center of debates about women’s education. Gynecologists manipulated social anxiety about shifting demographics and falling birthrates among white middle class women in order to legitimate their emerging discipline. In doing so, they couched American understandings of infertility in a politics of blame and demonized women for their inability to reproduce. Although doctors’ conversations about “sterility” primarily took place within the pages of journals published by all-male medical associations, many women engaged in this debate and challenged medical authority in the pages of popular magazines and newspapers. Female doctors, teachers, scholars, women’s college …

Redwood Roots: Stories Of Community Engagement At Hsu, Hsu Center For Community Based Learning

Redwood Roots Digital Magazine

Welcome to the inaugural edition of Humboldt State University’s Redwood Roots magazine. When we came up with the idea for this magazine, we wanted to highlight the many wonderful ways that students, faculty and community partners are engaging in community-based learning practices in and around Humboldt County. This project was a huge endeavor and we are grateful to our partners, both ongoing, such as the HSU Library Press team and the shorter term partners that donated their time to submit articles, develop the concept and layout for this magazine, and their many other contributions. We began this project in the …

Administration Of Canagliflozin For The Remission Of Metabolic Syndrome In Nondiabetic Adults, Corrie Asseo

Yale School of Medicine Physician Associate Program Theses

Metabolic syndrome is a critical risk factor for the development of type 2 diabetes mellitus and cardiovascular disease, two of the leading causes of death in the United States. With over one third of the adult population currently affected, this syndrome poses a serious health and economic burden. Lifestyle modification is the primary treatment, however only 50% maintain adherence. A single pharmacological therapy such as canagliflozin may overcome this lack of treatment adherence. Our purpose is to establish a difference between canagliflozin 300 milligrams daily plus lifestyle modification education and lifestyle modification education alone for the remission of metabolic syndrome …

Magnesium Exposure In Very Preterm Neonates And Adverse Gastrointestinal Outcomes, Giavanna G. Chirico

Yale School of Medicine Physician Associate Program Theses

Preterm birth is the leading cause of perinatal morbidity and mortality, especially among neonates born less than 32 weeks’ gestation. Magnesium sulfate is the standard treatment for seizure prevention in preeclampsia and for fetal neuroprotection in mothers at risk for preterm delivery. However, the consequences of antenatal magnesium exposure on the very preterm neonate’s gastrointestinal tract are not fully established. This study will determine whether elevated magnesium levels in very preterm neonates are associated with adverse gastrointestinal outcomes from birth to 4 months. Specifically, using a prospective cohort design, we will measure magnesium in umbilical cord blood of very preterm …

Vitamin D Supplementation In Fitzpatrick Skin Types Iv-Vi As Malignant Melanoma Adjuvant Treatment, Shikha Goyal

Yale School of Medicine Physician Associate Program Theses

Melanoma is the most lethal form of skin cancer and accounts for the majority of skin cancer deaths. Melanoma is prone to recurrence, and even with early surgical intervention relapse occurs in approximately one-third of patients. The current standard of care following excision is inconsistent and patients would benefit from adjuvant treatment to reduce recurrence rates. This randomized controlled study will investigate whether supplementation with vitamin D reduces risk of melanoma recurrence in adults with Fitzpatrick skin types IV-VI who have been diagnosed and treated for cutaneous melanoma. Outcomes will be measured by relapse-free survival rates over an 18-month period. …

The Impact Of Peer Education On Coronary Artery Bypass Surgery Readmission Rates, Melissa Ling

Yale School of Medicine Physician Associate Program Theses

Coronary artery bypass surgery is the most common cardiovascular operation performed in the United States. Coronary artery bypass surgery lowers rates of cardiovascular death by restoring circulation to cardiac tissue in patients with coronary artery disease. However, this surgery is associated with unacceptably high readmission rates, posing both health risks for the patient and a substantial financial burden on the healthcare system. Our objective is to investigate whether peer education can improve 30-day readmission rates of patients after coronary artery bypass surgery. Adult patients undergoing a coronary artery bypass surgery will either receive the usual standard of care or four …

Plant Defensin Antibacterial Mode Of Action Against Pseudomonas Species, Andrew E. Sathoff, Shawn Lewenza, Deborah A. Samac

Research & Publications

Background: Though many plant defensins exhibit antibacterial activity, little is known about their antibacterial mode of action (MOA). Antimicrobial peptides with a characterized MOA induce the expression of multiple bacterial outer membrane modifications, which are required for resistance to these membrane-targeting peptides. Mini-Tn5- lux mutant strains of Pseudomonas aeruginosa with Tn insertions disrupting outer membrane protective modifications were assessed for sensitivity against plant defensin peptides. These transcriptional lux reporter strains were also evaluated for lux gene expression in response to sublethal plant defensin exposure. Also, a plant pathogen, Pseudomonas syringae pv. syringae was modified through transposon mutagenesis to …

June 18-19, 2020, Ohio University Board Of Trustees Meeting Minutes, Ohio University Board Of Trustees

Board of Trustees Meeting Minutes

Meeting minutes document the activities of Ohio University's Board of Trustees.

Molecular Interplay Between Dormant Bone Marrow-Resident Cells (Bmrcs) And Ctcs In Breast Cancer., Debasish Boral, S Ray Kenney, Dario Marchetti, Haowen N. Liu

Pathology Research and Scholarship

Despite widespread knowledge that bone marrow-resident breast cancer cells (BMRCs) affect tumor progression, signaling mechanisms of BMRCs implicated in maintaining long-term dormancy have not been characterized. To overcome these hurdles, we developed a new experimental model of clinical dormancy employing patient-isolated Circulating Tumor Cells (de novo CTCs) and their injection in xenografts with subsequent tumor monitoring and CTC characterization (ex vivo CTCs). We hypothesized that significant distinctions exist between signaling pathways of bone marrow-homing vs metastasis-competent CTCs upon transplantation in xenografts. Comparative transcriptomic analyses of ex vivo vs de novo CTCs identified increased mTOR signaling-a critical pathway frequently dysregulated in …

Predictors Of Psychosocial And Physiological Distress In Colorectal Cancer Patients, Hyrum Eddington

Undergraduate Honors Theses

Distress among cancer patients has been broadly accepted as an important indicator of patient well-being. However, questions remain such as what patient characteristics are associated with high distress and whether patient-reported distress is correlated with distress biomarkers. To answer these questions, we performed a survey study of 238 colorectal patients in which we assessed patient-reported distress, possible contributors to that distress, and patient anxiety and depression. We also abstracted demographic and clinical information from patient charts and collected measures for salivary cortisol and sarcopenia. We conducted bivariate statistical analyses between patient demographics, clinical factors, and psychosocial measures with our three …

Development Of A Single-Stranded Dna-Binding Protein Fluorescent Fusion Toolbox, Katarzyna Dubiel, Camille Henry, Lisanne M. Spenkelink, Alexander G. Kozlov, Elizabeth A. Wood, Slobodan Jergic, Nicholas E. Dixon, Antoine M. Van Oijen, Michael M. Cox, Timothy M. Lohman, Steven J. Sandler, James L. Keck

Open Access Publications

Bacterial single-stranded DNA-binding proteins (SSBs) bind single-stranded DNA and help to recruit heterologous proteins to their sites of action. SSBs perform these essential functions through a modular structural architecture: the N-terminal domain comprises a DNA binding/tetramerization element whereas the C-terminus forms an intrinsically disordered linker (IDL) capped by a protein-interacting SSB-Ct motif. Here we examine the activities of SSB-IDL fusion proteins in which fluorescent domains are inserted within the IDL of Escherichia coli SSB. The SSB-IDL fusions maintain DNA and protein binding activities in vitro, although cooperative DNA binding is impaired. In contrast, an SSB variant with a fluorescent protein …

Pet Radiopharmaceuticals For Imaging Chemotherapy-Induced Cardiotoxicity, Jothilingam Sivapackiam, Monica Sharma, Thomas H Schindler, Vijay Sharma

Open Access Publications

PURPOSE OF REVIEW: Currently, cardiotoxicity is monitored through echocardiography or multigated acquisition scanning and is defined as 10% or higher LVEF reduction. The latter stage may represent irreversible myocardium injury and limits modification of therapeutic paradigms at earliest stages. To stratify patients for anthracycline-related heart failure, highly sensitive and molecularly specific probes capable of interrogating cardiac damage at the subcellular levels have been sought.

RECENT FINDINGS: PET tracers may provide noninvasive assessment of earliest changes within myocardium. These tracers are at nascent stages of development and belong primarily to (a) mitochondrial potential-targeted and (b) general ROS (reactive oxygen species)-targeted radiotracers. …

Plasmogamic Paternal Contributions To Early Zygotic Development In Flowering Plants, Yukinosuke Ohnishi, Tomokazu Kawashima

Plant and Soil Sciences Faculty Publications

Flowering plant zygotes possess complete developmental potency, and the mixture of male and female genetic and cytosolic materials in the zygote is a trigger to initiate embryo development. Plasmogamy, the fusion of the gamete cytoplasms, facilitates the cellular dynamics of the zygote. In the last decade, mutant analyses, live cell imaging-based observations, and direct observations of fertilized egg cells by in vitro fusion of isolated gametes have accelerated our understanding of the post-plasmogamic events in flowering plants including cell wall formation, gamete nuclear migration and fusion, and zygotic cell elongation and asymmetric division. Especially, it has become more evident that …

Toward A More Apparent Approach To Considering The Admission Of Expert Testimony, Thomas D. Schroeder

Notre Dame Law Review

This Article highlights lingering confusion in the caselaw as to the proper standard for the trial court’s discharge of its gatekeeping role for the admission of expert testimony. The Article urges correction of the faulty application of Daubert’s admonition as to “shaky but admissible” evidence as a substitute for proper discharge of the trial court’s gatekeeper function under Rule 104(a). The Article concludes with several suggestions for trial and appellate courts to consider for better decisionmaking in discharging their duty to apply Rule 104(a)’s preponderance standard to the elements of Rule 702.

"Of Substantial Religious Importance": A Case For A Deferential Approach To The Ministerial Exception, Allison H. Pope

Notre Dame Law Review

This Note argues that, in order to remain consistent with the Religion Clauses’ protection of religious autonomy, civil courts must defer to the religious group’s determination of which of its employees play a role “of substantial religious importance” within the organization in carrying out its religious mission under its tenets, and are therefore “ministers,” rather than investigate and make that determination themselves. Part I provides background information on the First Amendment and an overview of the circuit court and Supreme Court decisions that laid the foundation for, built, adopted, and applied the ministerial exception as described in Hosanna-Tabor. Part …

Vegetation And Large Carnivore Responses In An Encroached Landscape, Hugh Ellerman

School of Natural Resources: Dissertations, Theses, and Student Research

The Great Plains biome supports biodiverse plant and animal communities, provides a wide array of ecosystem services, and is depended upon by agricultural economies. Despite these advantages, however, Great Plains grasslands are becoming increasingly degraded by landcover changes due to agriculture and urbanization, fragmentation, loss of biodiversity and invasion by woody species. Woody encroachment is a biome-wide threat to Great Plains plant and wildlife communities and is therefore managed, though with variable success. I investigated the efficacy of invasive tree management projects in restoring tallgrass prairies in southeast Nebraska and regenerating oak gallery forests along the Niobrara River. I measured …

Advancing Human Health In The Decade Ahead: Pregnancy As A Key Window For Discovery: A Burroughs Wellcome Fund Pregnancy Think Tank., Yoel Sadovsky, Sam Mesiano, Graham J Burton, Michelle Lampl, Jeffrey C Murray, Rachel M Freathy, Anita Mahadevan-Jansen, Ashley Moffett, Nathan D Price, Paul H Wise, Derek E Wildman, Ralph Snyderman, Nigel Paneth, John Anthony Capra, Marcelo A Nobrega, Yaacov Barak, Louis J Muglia

Articles, Abstracts, and Reports

Recent revolutionary advances at the intersection of medicine, omics, data sciences, computing, epidemiology, and related technologies inspire us to ponder their impact on health. Their potential impact is particularly germane to the biology of pregnancy and perinatal medicine, where limited improvement in health outcomes for women and children has remained a global challenge. We assembled a group of experts to establish a Pregnancy Think Tank to discuss a broad spectrum of major gestational disorders and adverse pregnancy outcomes that affect maternal-infant lifelong health and should serve as targets for leveraging the many recent advances. This report reflects avenues for future …

“How Well Does Your Structural Equation Model Fit Your Data?”: Is Marcoulides And Yuan’S Equivalence Test The Answer?, James Peugh, David F. Feldon

Instructional Technology and Learning Sciences Faculty Publications

Structural equation modeling is an ideal data analytical tool for testing complex relationships among many analytical variables. It can simultaneously test multiple mediating and moderating relationships, estimate latent variables on the basis of related measures, and address practical issues such as nonnormality and missing data. To test the extent to which a hypothesized model provides an appropriate characterization of the collective relationships among its variables, researchers must assess the “fit” between the model and the sample’s data. However, interpreting estimates of model fit is a problematic process. The traditional inferential test of model fit, the chi-square test, is biased due …

In Search Of Trustworthy And Transparent Intelligent Systems With Human-Like Cognitive And Reasoning Capabilities, Nikhil R. Pal

Journal Articles

At present we are witnessing a tremendous interest in Artificial Intelligence (AI), particularly in Deep Learning (DL)/Deep Neural Networks (DNNs). One of the reasons appears to be the unmatched performance achieved by such systems. This has resulted in an enormous hope on such techniques and often these are viewed as all—cure solutions. But most of these systems cannot explain why a particular decision is made (black box) and sometimes miserably fail in cases where other systems would not. Consequently, in critical applications such as healthcare and defense practitioners do not like to trust such systems. Although an AI system is …

High-Efficiency Transformation Of Yeast By Electroporation, Lilly Ruell

Honors Theses

This paper analyzes and optimizes efficiency in the yeast transformation protocol using electroporation. Three variables were tested for optimization, they are the following: DNA concentration, cell density and electroporation voltage. Further verification of transformation was done through the analyzation of HPLC data to ensure protein production. The results conclude that DNA concentration was the most important dependent variable for transformation efficiency. A voltage of 2000V is the optimal condition to achieve efficient yeast transformation. Cell density had no observational difference in transformation efficiency at the range of DNA concentration necessary for research use. Improving this efficiency of the yeast transformations …

Aligning Voice And Communication With Identity – A Survey On Transgender And Gender Diverse Populations, Rachel T. Chalom

USF Tampa Graduate Theses and Dissertations

Purpose: This research has two goals. The first goal is to examine transgender (TG) and gender diverse (GD) voice and communication functioning and the impact of voice on their everyday lives. The second goal is to examine the knowledge, attitudes, and beliefs speech-language pathologists (SLP) have about the TG and GD community and to investigate the relationship between self- and listener-perception and its correspondence to quality of life (QoL).

Methods: A total of 59 participants took part in this research. The research was separated into two parts, the first included 24 TG and GD individuals who participated in a Qualtrics …

Mechanism Of Allosteric Inhibition In The Plasmodium Falciparum Cgmp-Dependent Protein Kinase, Philipp Henning, Eugen Franz, Madoka Akimoto, Friedrich W Herberg, Choel Kim, Giuseppe Melacini

Faculty, Staff and Students Publications

Most malaria deaths are caused by the protozoan parasite Plasmodium falciparum. Its life cycle is regulated by a cGMP-dependent protein kinase (PfPKG), whose inhibition is a promising antimalaria strategy. Allosteric kinase inhibitors, such as cGMP analogs, offer enhanced selectivity relative to competitive kinase inhibitors. However, the mechanisms underlying allosteric PfPKG inhibition are incompletely understood. Here, we show that 8-NBD-cGMP is an effective PfPKG antagonist. Using comparative NMR analyses of a key regulatory domain, PfD, in its apo, cGMP-bound, and cGMP analog–bound states, we elucidated its inhibition mechanism of action. Using NMR chemical shift …

Questions Concerning Attention And Stiegler’S Therapeutics, Noel Fitzpatrick

Articles

The article sets out to develop the concept of attention as a key aspect to building the possible therapeutics that Bernard Stiegler’s recent works have pointed to (The Automatic Society, 2016, The Neganthropocene, 2018 and Qu’appelle-t-on Panser, 2018). The therapeutic aspect of pharmacology takes place through processes that are neganthropic; therefore, which attempt to counteract the entropic nature of digital technologies where there is flattening out to the measurable and the calculable of Big Data. The most obvious examples of this flattening out can be seen in relation to the use of natural language processing technologies for …

Review Of Coast And Marine Ecosystems In Temperate Australia Demonstrates A Wealth Of Ecosystem Services, Sam Gaylard, Michelle Waycott, Paul Lavery

Research outputs 2014 to 2021

© Copyright © 2020 Gaylard, Waycott and Lavery. Temperate Australia has extensive and diverse coast and marine habitats throughout its inshore and offshore waters. The region includes the southernmost extent of mangroves, over 500 estuaries and coastal embayments, home to extensive meadows of seagrasses and tidal saltmarsh. In areas of hard substrate, rocky reefs are abundant and productive with large forests of macroalgae. Coastal regions can be densely populated by humans and often habitats can be degraded, polluted or lost, while some remain relatively isolated and pristine. These habitats provide services to society including provision of food, regulate our climate …

Research Productivity In Human Genetics During 2014 – 2018: A Scientometric Approach, Priya Saravanan, Natarajan Radhakrishnan, Abdoulaye Kaba

Library Philosophy and Practice (e-journal)

An attempt is made for bringing out the growth of literature on human genetics. Web of Science database has been used to retrieve the data of five years (2014-2018) by searching a keyword “Human Genetics" in the combined topics, abstract and keywords fields. The scientometric tools and techniques such as document type, year wise distributions, language, and country wise distribution are used for measuring the outputs. Findings of the study indicate that more than 1966 (20.51%) research articles were published in the year 2016. English was the dominant language with 9393 (97.9%) followed by German with 71(0.7%). For the contributing …

It's Time To Go Back To The Basics, Susan H. Davide

Publications and Research

Ultrasonic instrumentation is used today by many dental hygienists and dentists around the world. However, with the onset of the COVID-19 pandemic, dental procedures involving aerosol production are contraindicated, leading to the question, “Is it time to return to hand scaling?”