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Multiple Persistent Nodular Lesions In An Infant: Diagnosing Disseminated Juvenile Xanthogranuloma, Kourtney Kelly

Biochemistry and Molecular Biology

No abstract provided.

Molecular Risk Markers Define Risk Of Relapse In Myeloid Leukemia Of Down Syndrome Beyond Measurable Residual Disease., Jason N. Berman, Anupam Verma, Shelton Viola, Todd A. Alonzo, Yi-Cheng Wang, Lisa Eidenschink Brodersen, Michael Loken, Amy Beckman, Betsy Hirsch, Susana Raimondi, Karen M. Chisholm, Xiaotu Ma, Rhonda Ries, Soheil Meshinchi, Alan S. Gamis, Reuven Schore, Jeffrey W. Taub, E Anders Kolb, Todd Cooper, Johann Hitzler

Manuscripts, Articles, Book Chapters and Other Papers

Myeloid leukemia of Down syndrome (ML-DS) is a distinct form of pediatric acute myeloid leukemia (AML) that responds to reduced-intensity chemotherapy, as compared with non-DS AML that requires intensive chemotherapy and often stem cell transplant. While most patients with ML-DS have a favorable prognosis, outcomes for those with refractory or relapsed disease are dismal. Children's Oncology Group study AAML1531 introduced the use of measurable residual disease by multiparameter flow cytometry at the end of the first course of induction therapy (EOI-1 MRD) for risk stratification of treatment intensity. Of 280 patients with ML-DS who were enrolled, 41 were classified as …

International Consensus-Driven Recommendations For Patient-Reported Outcome Research Objectives In Early Phase Dose-Finding Oncology Trials: Optimise-Ror, Emily Alger, Olalekan Lee Aiyegbusi, Amylou C Dueck, Anna Minchom, Madeline Pe, John D Peipert, Claire Snyder, Stefan N Symeonides, Roger Wilson, Ethan Basch, Yu Qiao, Susan E Bates, Helen Bulbeck, Lizzie Dean, Massimo Di Maio, Aaron R Hansen, Olga Kholmanskikh, Ken Kobayashi, Dónal Landers, Christophe Le Tourneau, J Jack Lee, Brigette B Y Ma, Lynley V Marshall, Sheetal Patel, Joan Petrie, Gregory R Pond, Kieran Prior, Khadija R Rantell, John F Reeve, Olga Solovyeva, Nolan A Wages, Harald A Weber, Melanie J Calvert, Christina Yap

Faculty, Staff and Student Publications

Purpose: There is growing scientific interest in incorporating patient-reported outcomes (PROs) in early phase dose-finding oncology trials (DFOTs) to assess tolerability, inform dose selection, and guide later stage trial design. However, research indicates that PRO objectives in DFOTs are often unclear. The Incorporating Patient-Reported Outcomes in Dose-Finding Trials-Research Objectives Recommendations (OPTIMISE-ROR) project was established to support trialists to effectively incorporate PROs into DFOTs.

Methods: Using the Enhancing Quality and Transparency of Health Research (EQUATOR) Network's methodological framework, guideline development included the following: (1) a methodological review of published DFOTs incorporating PROs; (2) candidate item generation, refined through expert consultation; (3) …

A Quantitative Quasi-Experimental Study To Determine The Effectiveness Of Ufli And Iready Interventions For Third Grade Struggling Readers, Vada Kehrer

Doctoral Dissertations and Projects

The purpose of this quantitative quasi-experimental pretest-posttest study was to determine whether there is a significant difference in the growth in reading proficiency among third-grade struggling readers receiving different reading intervention programs: the University of Florida Literacy Institute (UFLI) or i-Ready curriculum-based interventions. The study is important because the National Assessment of Educational Progress (NAEP) has reported a concerning decline in literacy rates, particularly among students with dyslexia. The persistence of decline in reading proficiency stresses the urgent need for effective reading interventions. This study contributes to the existing literature on reading intervention programs for struggling readers. The sample included …

A Quantitative Causal-Comparative Study Of The Effect Of Dynamic Versus Static Visualization And Gender On Middle School Teachers' Mathematics Anxiety, Daniel Kobina Lindsay

Doctoral Dissertations and Projects

The purpose of this quantitative causal-comparative study was to determine if there is a significant difference in teachers' mathematics anxiety on the effect of instruction-based dynamic versus static visualization and gender among teachers in middle schools. This study is critical because it addresses policies and pedagogical practices that address mathematics anxiety among middle school teachers. The gender of teachers and the medium of instructional delivery play a crucial role in assessing these teachers' engagement and achievement in the United States educational system. The sample (n = 293) was composed of teachers, divided into groups based on their instruction method and …

A Descriptive Phenomenological Study Of South Texas Non-Denominational Hispanic Ministry Leaders' Spiritual Formation Through Total Worship, Wendy Méndez

Doctoral Dissertations and Projects

Spiritual formation transforms a believer’s relationship with Christ. For ministry leaders, especially volunteers, this process may be enhanced through worship practices. Understanding worship as a holistic lifestyle—beyond just musical or liturgical expression—had a profound influence on participants’ personal and spiritual development in this study. Despite the abundance of literature on worship and spiritual formation, a gap existed in understanding how total worship influenced the spiritual lives of volunteer leaders, particularly in culturally diverse communities. This study addressed the lack of research on the role of total worship in the spiritual formation of volunteer leaders in predominantly Hispanic, English-speaking, non-denominational, charismatic …

Exploring The Relationships Between Differentiation Of Self, Family Unit Functioning, And Posttraumatic Growth In Adult Female Survivors Of Domestic Minor Sex Trafficking, Samantha Stokesberry

Doctoral Dissertations and Projects

The purpose of this dissertation was to explore the relationships between differentiation of self (DoS), family unit functioning (FUF), and posttraumatic growth (PTG) in adult female domestic minor sex trafficking (DMST) survivors in the United States. A Bowen Family Systems Theory framework was used for the theoretical foundation of this study and the research was explored from a Christian worldview. A sample of 30 adult female DMST survivors between the ages of 25-55 completed an anonymous online survey that included four measures: a demographics form, The Differentiation of Self Inventory – Revised (DSI-R), the Family Unit Functioning Questionnaire (FUF-Q), and …

Examining The Effect Of Enhanced Retrieval Practice With Or Without Artificial Intelligence On Task Value And Self-Efficacy Of College Students: A Quasi-Experimental Study, Duane N. Stutzman

Doctoral Dissertations and Projects

The purpose of this quantitative quasi-experimental study was to determine if a significant difference exists in college students perceived task value and self-efficacy when using different forms of retrieval practice enhanced with or without artificial intelligence. This study is important because task value and self-efficacy may have an impact on student motivation and engagement; therefore, the study adds to the literature demonstrating that retrieval practice can help improve active, rather than passive learning. The sample was composed of 140 undergraduate students enrolled in a hybrid health science course at a large university in the Midwest. After participants completed their assigned …

A Phenomenological Study Of Complex Post-Traumatic Stress Disorder In Combat Deployed Women Combat Veterans, Caren Valencia Chen

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to delineate factors that impact women combat veterans with Complex Post-Traumatic Stress Disorder (C-PTSD) after deployment and completion of military service. The theory guiding this was Strauss and Corbin’s grounded theory. The conceptual framework guiding the study was Crenshaw's intersectionality theory. C-PTSD is often diagnosed with service members throughout their time in the military, and after their time in the military is complete. The central research question, “What are the lived experiences of women combat veterans diagnosed with C-PTSD?” was addressed through interviews with focus groups. The sub-questions to analyze direct correlation issues …

The Schizophrenia Effect: Families Facing Schizophrenia-Spectrum Disorders, Ginger A. Christmas

Doctoral Dissertations and Projects

Schizophrenia is primarily known for its bizarre psychosis, as the brain struggles to distinguish between what is real and what is not. This qualitative study employed constructive, interpretative phenomenological analysis (IPA) to explore the idea that families with a family member diagnosed with a schizophrenia-spectrum disorder (SSD) in the United States have specific needs, which may include social and spiritual support and integration into treatment. While the needs of families facing SSD have been studied in non-Western countries, the schizophrenia effect on families in the U.S. remains less understood. A purposive sample of 11 individuals, representing 15 family members with …

Exploring The Perceived Influence Of Exposure To Secondary Trauma On Educators: A Hermeneutic Phenomenological Study, Katina M. Perry

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to understand the influence of secondary trauma on educators who work with students residing in low-income urban communities. Secondary trauma was generally defined as the emotional response that occurs when individuals are indirectly exposed to the traumatic experiences of others. The theory that guided this study was Lazarus and Folkman’s transactional model of stress and coping, as its emphasis on the interplay between an individual’s perceived psychological stress, coping, and cognitive appraisals was resourceful for educators exposed to student trauma. The central research question that guided this study was “How does secondary …

The Shared Experiences Of High Functioning Autistic Adults Receiving Mental Health Care In The Texas Metroplex: A Phenomenological Study, Katherine Ivey Marie Vaughan

Doctoral Dissertations and Projects

The purpose of the study is to describe the lived experiences of high functioning autistic adults who have engaged in mental health services in mental health services in Texas. Individuals with autism often face unique challenges, such as heightened sensory intake and cognitive inflexibility, which may complicate traditional therapeutic interventions. The theories that guided the study were the biopsychosocial model, social cognitive theory, the neurodiversity paradigm, and cognitive-behavioral theory, all exploring how cognitive processes influence emotions and behaviors in neurodiverse populations. Using a qualitative phenomenological design, semi-structured interviews were done with adults with high functioning autistic adults. Analysis of the …

Training The Church To Support Sufferers Of Mental Illness Through Comfort Clinics, Jonathan D. Blankenship

Doctoral Dissertations and Projects

The problem at Laurel Baptist Church (LBC) is the lack of trained members who are equipped to support those suffering from mental illness. The purpose of this DMIN action research project is to create Comfort Clinics, a structured program to train members to support sufferers of mental illness. Normative-sized churches are often uninformed on the topic of mental illness. Subsequently, in those environments, stigmas are nurtured, sufferers feel unseen, and church members lack the necessary training to provide the comfort and support that mental sufferers need. Building on the ecclesiastical call to “comfort those who are in any affliction” (2 …

The Psychometric Use Of Word Embeddings, Thomas Benjamin Lyle Wasden

Doctoral Dissertations and Projects

This quantitative study examined the feasibility of categorizing individuals by English-language competency using word embeddings derived from language samples obtained from these individuals and by viewing word embeddings as a psycholinguistic construct. Word embeddings have been shown to be a versatile tool for performing a large number of important natural language processing (NLP) tasks, as well as a plausible model for some processes in the human mind, including processes within the domain of psycholinguistics. This research seeks to build upon previous research by showing that word embeddings may shed light on the underlying neural representation of semantic entities being acquired …

Individual Differences In Alexithymia Modulate Cognition-Emotion Interactions In Daily Life Ongoing Experiences, Anqi Lei, Md Faysal, Louis Chitiz, Raven Wallace, Samyogita Hardikar, Brontë Mckeown, Jonathan Smallwood, Elizabeth Jefferies, Robert Leech, Nerissa Ho

School of Psychology

Individual differences modulate our thoughts and emotional experiences, yet how thought and emotion interact in daily life remains largely unclear. We leverage alexithymia, a trait reflecting atypical emotional awareness, to reveal these interactions in naturalistic settings. Using multi-dimensional experiencesampling via smartphones, we captured moment-to-moment thought patterns and concurrent affective states (valence, arousal, stress) in people’s daily life (N = 190 undergraduate students, age range = 18 to 36, 159 females). Using Principal Component Analysis and Linear Mixed Models, we identified four thought dimensions that relate differently to these affective states: future-self orientation, intrusive distraction, sensory engagement, and task-focus. Alexithymia modulated …

Visum Et Repertum Dan Proses Peradilan Pidana : Pendayagunaan Ilmu Kedokteran Dalam Sistem Peradilan Pidana, Dr. Abdul Mun'im Idris

Jurnal Hukum & Pembangunan

Abstract

Pemidanaan Yang Bagaimana, Loebby Loqman. S.H.

Jurnal Hukum & Pembangunan

Abstract

Masalah Lingkungan Hidup Dan Dampak Sosialnya, Prof. Dr. Soerjono Soekanto, S.H., M.A.

Jurnal Hukum & Pembangunan

Abstract

Optimization Of Turning Process Parameters For Enhanced Surface Quality In Aluminum Alloy Aa2024, Nashwan Mahmood, Esmail Mahmood, Saya Mahmood, Mohammad Aziz, Deary Ahmad

Engineering and Technology Journal

Surface roughness is a critical parameter that profoundly influences the functionality and performance of materials and components across various industries. Additionally, estimating the ideal machining parameter circumstances is the best way to minimize costs and get the item's surface quality. This research investigated four factors- depth of cut, spindle speed, feed, and nose radius- for the turning of aluminum alloy AA2024 to estimate the surface roughness. The study's experimental efforts were done by utilizing a manual turning machine, and the experiment setup used the Taguchi method of L18 array orthogonal (OA). The Taguchi approach is employed to optimize the selection …

Validation Of The Simulation Implant Design Approach Based On Ct Scan Images And The Biomechanical Performance Response Of Rehabilitated Skull Bones, Nareen Obaeed, Wisam Hamdan

Engineering and Technology Journal

Appropriate cranial implants are essential due to a worldwide population that is aging and the rising incidence of trauma. One key element affecting cranial implants' performance is their biomechanical behavior in human skull bones. This paper describes a high-quality cranial implant design approach for the defective skull based on computed tomography CT scan images and the biomechanical performance analysis of rehabilitation human skull bones. The valuable contribution of this work is the effective utilization of finite element analysis FEA to contrast the material behaviors of Polymethylmethacrylate PMMA cranial implants and autologous skull bone during rehabilitation as exposed to external trauma. …

Clay Barriers Performance In Landfills: A Review., Kawther Al-Soudany, Mohammed Fattah, Falah Rahil

Engineering and Technology Journal

Clay barriers have garnered much interest in environmental engineering because they successfully reduce various ecological dangers, including groundwater contamination, the migration of leachate from landfills, and waste disposal in landfills. This review paper aims to provide a comprehensive analysis of the features, uses, and performance of clay barriers in various environmental conditions. The problem this review paper addresses is the dangers of waste disposal sites, which emphasizes landfills' harm to the ecosystem and explains why natural clays are often employed as barriers surrounding landfills to keep out pollution. The paper aims to provide an update on essential subjects about barrier …

Synthesized Of Gallium Nitride/Psi Nano Thin Films Using 532 Nm Wavelength By Pulsed Laser Deposition Technique, Abeer Abbas, Ali Alwahib, Makram Fakhri, Subash C. B. Gopinath, U. Hashim

Engineering and Technology Journal

The porous silicon (PSi) substrate was accurately synthesized using photoelectrochemical etching. A Nanofilm gallium nitride (GaN) was then precisely deposited on this PSi substrate using pulsed laser deposition (PLD). The x-ray diffraction (XRD) investigation revealed the GaN layer's distinct crystalline structure along the (002) plane, with a precise crystallite size of 21.57 nm. This precision in the deposition process enhanced both the surface morphology and film quality. In the atomic force microscope (AFM), oval particles were evenly distributed across the entire surface, and the RMS of the surface was 27 nm with a 20.63 nm surface roughness. A field emission …

Optimal Operational Conditions Of Pla/Pbat Mixed Matrix Membrane For The Treatment Of Oily Wastewater, Maryam Ghadhban, Khalid Rashid, Adnan Abdulrazak, Hicham Meskher, Yacine Benguerba, Emad Yousif Al-Sarraj, Qusay Alsalhy

Engineering and Technology Journal

This study aims to optimize the operational variables influencing the incorporation of Hesperidin nanoparticles (HSP NPs) into poly(lactic acid)/poly(butylene adipate-co-terephthalate) (PLA/PBAT) for manufacturing mixed matrix membranes (MMMs) for oily wastewater treatment. An optimization method was employed to determine the optimal values for key process factors to achieve specific flux and rejection rates exceeding required levels. Statistical techniques such as response surface methodology (RSM) and analysis of variance (ANOVA) were used to enhance performance on a larger scale. This research investigated the impact of operating parameters on the flux and oil rejection of PLA/PBAT/HSP membranes across all samples. The variables studied …

Applications Of Artificial Intelligence In Nanotechnology, Shahad Eabd Alrida, Ola Obed, Elaf Taha, Thamer Abdullah, Mustafa Hathal, Viola Somogyi

Engineering and Technology Journal

Artificial intelligence (AI) is emerging as a prominent technological advancement. It is the act of replicating human intelligence for many purposes. In contrast to conventional methodologies, artificial intelligence (AI) is undergoing tremendous advancements. The present state of artificial intelligence (AI) technology enables them to effectively address numerous intricate difficulties with proficiency comparable to a human's. The significance of advancements in AI is particularly evident in machine learning, where the techniques and algorithms are effectively applied to address many problems, including those in nanotechnology. In contemporary nanotechnology, it is crucial to expedite the search for the most favorable synthesis parameters while …

Survey Of Near-Field Wireless Communication And Power Transfer For Biomedical Implants, Hala Abduljaleel, Saad Mutashar, Sadik Gharghan

Engineering and Technology Journal

Bio-implanted medical devices with electronic components play a crucial role due to their effectiveness in monitoring and diagnosing diseases, enhancing patient comfort, and ensuring safety. Recently, significant efforts have been conducted to develop implantable and wireless telemetric biomedical systems. Topics such as appropriate near-field wireless communication design, power use, monitoring devices, high power transfer efficiency from external to internal parts (implanted), high communication rates, and the need for low energy consumption all significantly influence the advancement of implantable systems. In this survey, a comprehensive examination is undertaken on diverse subjects associated with near-field wireless power transfer (WPT)-based biomedical applications. The …

Characterization Of Alkaline Treated Raffia Palm Fibres As Reinforcement In Polymer Composite, Ipilakyaa Daniel, Tile Emmanuel, Nyior Bem, Gundu Terfa

Engineering and Technology Journal

The characterization of raffia palm fibre (RPF) for reinforcement in polymer composite for specialized applications was studied. The fibres were treated with NaOH solution and subjected to a tensile strength test. The fibres were also subjected to spectroscopy using Fourier transform infrared (FTIR), energy dispersive x-ray fluorescence (EDXRF), and x-ray diffraction (XRD). The study found that the alkaline-treated RPF presented a tensile strength of 195 MPa and Young’s modulus of 91.76 MPa. The strain at maximum stress in the fibre was found to be 2.125%. FTIR spectra of treated raffia palm fibres revealed that the fibres are characterized by O-H …

Production Of Copper Nanoparticles Using Alpha-Amylase Enzyme By An Electrochemical Deposition Method, Neamah Hadi, Mohammad Hafiz, F. Sayyid, Wan Wan Isahak

Engineering and Technology Journal

This study aims to explain the effect of adding the bioactive substance (alpha enzyme) to the electrolyte solution using electrochemical deposition. Through which copper nanoparticles are manufactured, the originality of the research lies in the presence of this addition as a new method in manufacturing nanoparticles in an electrochemical manner, as the alpha-amylase enzyme is extracted from camel saliva, and the product has been diagnosed using (EDX) and scanning electron microscope (FE-SEM) techniques. , Dynamic Light Scattering (DLS) technology, and Zeta potential. The proposed method is an easy, inexpensive, and environmentally friendly method where the alpha enzyme was used as …

Optimization Of Mechanical And Biocompatible Properties Of Znos-Fiber Membranes, Dalia Jomaa, Abbas Hussein, Jamal Dawood

Engineering and Technology Journal

This study uses electro-spinning techniques to create a poly(vinyl alcohol)-chitosan-zinc oxide nanoparticles (PVA+CS)+ZnO NPs system in three concentrations of ZnO for application as composite nanofibers for wound treatment applications and   Employing the Taguchi technique to optimize the mechanical characteristics via a four-level experimental design process (L16). Numerous techniques have been utilized to characterize the nanofibrous scaffolds: contact angle measurement, cytotoxicity testing, proliferation testing, evaluation of antimicrobial activity, Fourier Transform Infrared Spectroscopy (FTIR), Field Emission Scanning Electron Microscopy (FESEM), Energy Dispersion X-ray Spectroscopy (EDX), and a comparative experimental study involving the determination of hardness using the Nanoindentation method for (PVA+CS)+ZnO. The …

Mxene (Ti C Tx) Based Nanosheet Photocatalysts For Water Remediation: Challenges And Recent Developments, Hadeel Abbas, Khalid Abbas, Ahmed Al-Ghaban

Engineering and Technology Journal

Two-dimensional nano structural compounds are attracting the focus of researchers worldwide. The need to treat wastewater and prevent the release of hazardous substances into the environment has increased because of growing environmental awareness. New compounds, most of which are not biodegradable, have emerged due to rising consumer expectations. Due to their distinctive chemical and physical characteristics, MXene has lately been recognized as an exciting option. The strong hydrophilicity of MXene makes them a promising candidate for environmental remediation methods like photocatalysis, natural chemical nature, and powerful electrochemistry—adsorption, membrane separation, and electrocatalytic sensors for identifying pollution. MXene has strong surface functional …

Antibacterial Improvement With Multilayer Of Bio-Composite Coatings Produced By Electrophoretic Deposition, Noor Al-Ali, Makarim Abdulkareem, Iman Anoon

Engineering and Technology Journal

In this study, multi-structured coatings of biocompatible and antibacterial materials on a 316L stainless steel (SS) implant have been electrophoretically deposited for orthopedic applications. Two layers of composite coatings have been deposited; the first layer of composite coating biopolymer layer consists of (chitosan with Gelatin) and the second composite coating layer of bio-ceramic comprises Hydroxyapatite with chitosan. The first layer was deposited at (3 g/L concentration of Gelatin, 20 voltage, and 3 min and 0.5 g/L chitosan) parameters, and the second layer was deposited at (6 g/L, 40 voltage, 1 min, and 0.5 g/L chitosan) parameters. In this study, the …