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Manipulating Genome Of Diploid Potato Inbred Line Solanum Chacoense M6 Using Selectable Marker Gene, Sarbesh Das Dangol, İlknur Yel, Mehmet Emi̇n Çalişkan, Allah Bakhsh

Turkish Journal of Agriculture and Forestry

The development of transgenic potatoes is imperative to investigate various gene functions as well as to develop robust potato varieties resistant to different biotic and abiotic stresses. Directing a potato breeding program from cultivated tetraploids to self-compatible diploid lines will be highly helpful for potato breeders. However, diploid potatoes are considered recalcitrant to regeneration. We aimed to develop a protocol for the transformation of diploid Solanum chacoense M6 potatoes using leaf, internodes, and microtubers as the explants. Agrobacterium tumefaciens strain GV2260 harboring pBIN19 expression vector containing gusA gene (interrupted by an intron to induce expression from eukaryotic cells) was used …

Chemosensitizing Effect Of Streptomyces Crude Extract On Cisplatin-Induced Apoptosis In Human Lung Cancer H460 Cells, Theint Myat Noe Paing

Chulalongkorn University Theses and Dissertations (Chula ETD)

Although cisplatin has been considered as a first-line chemotherapeutic drug for the treatment strategy of lung cancer, its curative efficacy is limited by the occurrence of drug resistance and adverse effects. The application of non-toxic natural products for sensitization of cancer cells to conventional drugs is a recent novel strategy for cancer management to tackle these problems. This study aims to investigate effective chemosensitizer produced by Streptomyces sp. on the growth inhibition of human H460 lung cancer cells. Herein, three of eight strains isolated from peat swamp forest, Yala Province, Thailand which showed good purity analyzed by 16S rRNA sequencing …

โครงการวิจัยแนวทางการแปลถ้อยคำที่สะท้อนอุปลักษณ์เชิงมโนทัศน์ในตัวบทโฆษณาผลิตภัณฑ์เครื่องสำอางบนเว็บไซต์จากภาษาอังกฤษเป็นภาษาไทย, อรสุรางค์ แสงสมสุรศักดิ์

Chulalongkorn University Theses and Dissertations (Chula ETD)

สารนิพนธ์ฉบับนี้มุ่งศึกษาอุปลักษณ์เชิงมโนทัศน์ในตัวบทโฆษณาผลิตภัณฑ์เครื่องสำอาง รวมถึงศึกษากลวิธีการถ่ายทอดอุปลักษณ์เชิงมโนทัศน์จากต้นฉบับไปยังฉบับแปล การวิจัยนี้รวบรวมข้อมูลผลิตภัณฑ์เครื่องสำอางในกลุ่มผลิตภัณฑ์บำรุงผิวและเครื่องสำอางสำหรับตกแต่งทั้งหมด 240 ผลิตภัณฑ์จากเว็บไซต์ตราสินค้าที่มีทั้งภาษาไทยและภาษาอังกฤษ ผู้วิจัยศึกษาแนวคิดอุปลักษณ์เชิงมโนทัศน์ตามแนวภาษาศาสตร์ปริชานของ Lakoff และ Johnson (2003) แนวทางการระบุรูปภาษาแสดงอุปลักษณ์จากกลุ่มนักวิชาการ Pragglejaz Group (2007) และการจัดประเภทกลุ่มคำศัพท์ตามวงความหมายจากงานวิจัยเกี่ยวกับอุปลักษณ์เชิงมโนทัศน์ในตัวบทประเภทต่าง ๆ รวมถึงการศึกษาลักษณะภาษาโฆษณาและประเภทอุปลักษณ์ที่พบในโฆษณาเครื่องสำอางในภาษาอังกฤษและภาษาไทย และจากการศึกษาแนวทางการแปลอุปลักษณ์ตามแนวคิดแบบดั้งเดิมและตามแนวภาษาศาสตร์ปริชาน ผู้วิจัยได้เลือกใช้กรอบการวิเคราะห์กลวิธีการแปลที่ผสมผสานกันของ Deignan et al. (1997) Schäffner (2004) และ Toury (1995) ผลการวิจัยพบว่า ในตัวบทโฆษณาเครื่องสำอางภาษาอังกฤษที่คัดเลือกมามีอุปลักษณ์ทั้งหมด 29 ประเภท มีจำนวนรูปภาษาที่แสดงอุปลักษณ์ทั้งหมด 1,391 ตัวอย่าง ผู้วิจัยเลือกอุปลักษณ์ที่พบสูงสุดใน 10 อันดับแรก ได้แก่ อุปลักษณ์สงคราม แสง มนุษย์ สุขภาพ พืชและการเพาะปลูก สิ่งทอและเครื่องนุ่งห่ม เครื่องจักร ศิลปะ อาหารและโภชนาการ และภาชนะ ซึ่งจำนวนรูปภาษาที่แสดงอุปลักษณ์ทั้งหมด 1,166 ตัวอย่าง นำมาวิเคราะห์อุปลักษณ์ที่พบในฉบับแปลและกลวิธีการแปล พบว่าภาษาไทยและภาษาอังกฤษมีอุปลักษณ์ทั้งหมดนี้เหมือนกัน ผลการวิเคราะห์กลวิธีการแปลเป็นไปตามสมมติฐานที่ตั้งไว้ กล่าวคือ พบว่ากลวิธีการแปลที่พบมากที่สุดคือ 1) การแปลโดยรักษามโนทัศน์เดิม แต่รูปภาษาแสดงอุปลักษณ์ต่างจากต้นฉบับ ร้อยละ 51.41 ตามด้วย 2) การแปลโดยรักษามโนทัศน์เดิม และรูปภาษาแสดงอุปลักษณ์ตรงตามต้นฉบับ ร้อยละ 26.90 3) การแปลโดยไม่รักษามโนทัศน์ (ไม่มีรูปภาษาแสดงอุปลักษณ์) ร้อยละ 12.93 4) การแปลโดยใช้มโนทัศน์ที่แตกต่างกัน ร้อยละ 4.62 และ 5) การละไม่แปล ร้อยละ 4.11 นอกจากนี้ ยังพบว่ามีการเพิ่มมโนทัศน์ที่ไม่ปรากฏในต้นฉบับเข้ามาในฉบับแปลด้วย โดยสรุป การถ่ายทอดอุปลักษณ์เชิง มโนทัศน์ในตัวบทโฆษณาเครื่องสำอางจากภาษาอังกฤษเป็นภาษาไทแทบไม่พบปัญหาในการแปลที่มาจากปัจจัยทางวัฒนธรรมซึ่งอาจเป็นเพราะวัฒนธรรมปลายทางรับค่านิยมและวัฒนธรรมจากต่างชาติโดยเฉพาะเรื่องความงามมาอย่างยาวนาน จึงสามารถรักษามโนทัศน์เดิมในต้นฉบับได้เป็นส่วนใหญ่ ส่วนกลวิธีการแปลอื่น ๆ แสดงให้เห็นการปรับบทแปลในตัวบทโฆษณาเครื่องสำอาง

The Policy State And The Post-Truth Presidency, Philip Rocco

Political Science Faculty Research and Publications

No abstract provided.

Stability Of The Learning Behaviors Scale, Nikki Davidson

Masters Theses

Learning behaviors are observable actions, habits, and manifestations of attitudes that facilitate learning, such as persevering at difficult tasks, showing interest in academic subjects, demonstrating care and concern about classwork, and graciously accepting feedback (Buchanan, McDermott, & Schaefer, 1998). Assessment of these learning behaviors is an essential first step to effective intervention. It is important to know which learning behaviors to target and the degree of deficit in order to remediate learning problems. The present study examined the medium length (two-month) stability of scores obtained from the Learning Behaviors Scale (McDermott, Green, Francis, & Stott, 1999). Fifty K-8 teacher rater …

Transcriptome Analysis Of Neuro-2a Cells Treated With Asiatic And Madecassic Acid, Fatimah M. Alqam

Masters Theses

Traditional herbal medicine is ingrained as a source of therapeutic compounds to medicate various diseases. The family Araliaceae (Ginseng family) is rich in traditional medicine species, such as Centella asiatica (CA). For many centuries, CA has been used by the indigenous Indian and Chinese in Ayurvedic and traditional medicine, respectively, to improve intelligence, learning, memory, and cognitive performance. Previous studies on cell culture and animal models supported the beneficial effects of CA on the nervous system. However, the exact composition of CA extract and its molecular mechanism that leads to neuroprotection is still unclear. We examined the effect of asiatic …

Genetic And Cellular Models For The Study Of Ptk2b And Adam10 In Adaptive Thermogenesis And Metabolism, Jared S. Farrar

Theses and Dissertations

In a cellular model, we demonstrate that the non-receptor protein tyrosine kinase 2 beta (PTK2B) plays a critical role in mouse cultured beige adipocyte differentiation. CRISPR/Cas9-mediated knock-out of Ptk2b results in non-differentiating white adipocytes and differentiated beige adipocytes with significantly reduced thermogenic gene and protein expression, enlarged lipid droplet size, and altered mitochondrial respiration. Together, these data in a cell culture system provide evidence for a role of PTK2B in the differentiation of mouse beige adipocytes.

In the process of developing a new mouse model utilizing the adipocyte selective Adipoq-Cre transgenic mouse, strong genetic linkage between a gene …

Caffeine Use And Associations With Sleep In Adolescents With And Without Attention-Deficit/Hyperactivity Disorder (Adhd), Caroline N. Cusick

Theses and Dissertations

The objective of this study was to compare caffeine consumption in the morning, afternoon, and evening in adolescents with and without Attention Deficit/Hyperactivity Disorder (ADHD) and examine associations with sleep functioning. Participants were 302 adolescents (ages 12-14) with (n=140) and without (n=162) ADHD. Adolescents wore actigraph watches to assess total sleep time and wake after sleep onset and reported on their sleep-wake problems and the number of caffeinated beverages consumed per day in the morning, afternoon, and evening. Parents reported on adolescents’ difficulties initiating and maintaining sleep. Chi-square analyses, odds ratios, and path analyses were conducted. Analyses controlled for sex, …

A Review Of Factors, Seating Design, And Shape Capture Methods For Reducing Pressure Injury Risk, John A. Damiao

Theses and Dissertations

This dissertation in the form of three papers ready for submission to peer-reviewed journals is submitted toward the requirements of the PhD in Health Related Sciences program at Virginia Commonwealth University. Chapter One provides an introductory overview of the project, including: (a) an overview of pressure injuries, (b) the impact of seating as an intervention, and (c) aims of the three-paper dissertation in addressing various aspects of pressure injury prevention. Each paper is unique and singular in its focus, yet all share the overlying aim of addressing pressure injury risk associated with wheelchair seating. Paper One describes the unique facilitators …

Culturally-Relevant Factors That Influence Healthy Eating Among African American College Students, Danyel Smith

Theses and Dissertations

Obesity is a national epidemic in the US, disproportionately affecting African Americans, such that the obesity prevalence in African Americans (49.6%) surpassed the national prevalence (42.4%) in 2018. Those same disparities exist at the collegiate level, such that 27.4% of a sample of African Americans college students had obesity, surpassing the national prevalence of obesity (12.1%) in 2018. Diet, an important driver of obesity, is influenced by several psychological, social, and environmental factors. However, cultural factors influencing diet are understudied among African American college students. The overarching goal of the current study was to identify culturally-relevant factors that promote healthy …

Profiles Of Adjustment Among Children In Institutional Care In Ghana: Predictors Of Positive Functioning, Anna W. Wright

Theses and Dissertations

Worldwide, approximately 2-8 million children reside in institutional care, which can lead to developmental setbacks. Given the need for institutional care persists, it is important to continue investigating which improvements can be made to provide optimal care. The current mixed-methods study included participants from Accra, Ghana. Study 1 involved cluster analyses to determine patterns of adjustment for 100 children in institutional care (CIC) (M age = 13.31 years, SD = 3.14; 40% female) and 100 children in families (CIF) (M age = 13.37 years, SD = 3.08; 40% female) across several domains. ANOVA was used to evaluate whether …

Taking The Water, Alison Ho

Theses and Dissertations

“The baby boomer generation is about to transform into the largest elderly population in human history, changing how everyone lives, large and small. All of this will directly affect recreation and leisure professionals especially in leisure programming” (Sperezza & Banerjee, 2010, p. 197). In 2012, there were 43.1 million people in the United States that were aged 65+ and it is predicted that by 2050, that number will rise to 83.7 million (Ortman, Velkoff, Hogan, 2014). Baby boomers are more physically active than previous generations and many will now live 20% - 25% of their lives in active retirement. There …

An Intuitive Eating Intervention For College Women With Disordered Eating: Evaluating Two Accessible And Affordable Approaches, Carolyn B. Burnette

Theses and Dissertations

Undergraduate women of all racial and ethnic groups engage in disordered eating behaviors (DEBs) at alarming rates. Most women do not receive treatment, with the largest disparities observed in women of color and those at higher weights. Prevailing interventions have limitations that could exacerbate these disparities, such as an emphasis on the thin ideal, which is often considered less relevant for some women of color. This is concerning, as disordered eating is often chronic and symptom crossover is common. Thus, a transdiagnostic, inclusive secondary prevention approach could enhance outcomes by addressing the spectrum of DEBs in diverse women. The purpose …

Demonstration Of Reciprocal Diurnal Variation In Human Serum T3 And Rt3 Concentration Demonstrated By Mass Spectrometric Analysis And Establishment Of Thyroid Hormone Reference Intervals., Qian Sun, Lívia Avallone, Brian Stolze, Katherine A Araque, Yesim Özarda, Jacqueline Jonklaas, Toral Parikh, Kerry Welsh, Likhona Masika, Steven J Soldin

Articles, Abstracts, and Reports

Background: There has been a wide range of reference intervals proposed in previous literature for thyroid hormones due to large between-assay variability of immunoassays, as well as lack of correction for collection time. We provided the diurnal reference intervals for five thyroid hormones, namely total thyroxine (TT4), total triiodothyronine (TT3), free thyroxine (FT4), free triiodothyronine (FT3), and reverse T3 (rT3), measured in serum samples of healthy participants using a liquid chromatography/tandem mass spectrometry (LC-MS/MS) method.

Methods: Couplet serum samples (a.m. and p.m.) were collected from 110 healthy females and 49 healthy males. Healthy volunteers were recruited from four participating centers …

Our Hopes For Nutritional Psychiatry And Fatphobia: An Exploration Of The Difficulties And Potential For Interdisciplinary Study, Casey Troost

The Synapse: Intercollegiate science magazine

No abstract provided.

The Nagoya Protocol And The Legal Structure Of Global Biogenomic Research, Sam F. Halabi, Michelle Rourke, Gian Luca Burci, Rebecca Katz

Faculty Publications

As life sciences technologies have advanced, so too has the potential for these international collaborations to lead to breakthrough medicines, enhance food security, and protect ecological systems. The linchpin of this progress is the development of high throughput genetic sequencing technologies. Researchers are now able to generate and compare large stretches of DNA - 1 million bases or more - from different sources quickly and inexpensively. Such comparisons can yield massive amounts of information about the role of inheritance in susceptibility to infection and illness as well as responses to environmental influences. In addition, the ability to sequence genomes more …

Early Access To Unapproved Medicines In The United States And France, Erika Lietzan

Faculty Publications

In 2018, President Trump signed a federal "right to try" law, claiming that it would give desperately ill patients earlier access to unapproved medicines, by allowing the patient, doctor, and drug company to arrange for access without federal oversight. Critics of the law argued that it would not meaningfully increase access to experimental medicines, because federal oversight was not the obstacle in the first place. And they were correct. U.S. law already permitted companies to provide terminally ill patients with early access to unapproved medicines. The problem was instead that companies did not take advantage of this option. This Article …

Video Advance Directives: Growth And Benefits Of Audiovisual Recording, Thaddeus Pope

Faculty Scholarship

The key question in Cruzan v. Director, Missouri Department of Health was one of substantiation and evidence: how can the incapacitated patient’s surrogate decision maker prove that the health care decisions she makes on the patient’s behalf are the same health care decisions that the patient would have made for herself? Answering this question, the Court observed that an advance directive would constitute adequate proof because an advance directive constitutes clear and convincing evidence of a patient’s wishes.

Today, clinicians and policymakers no longer focus on the constitutional question of how much evidence state law may require from a patient’s …

Safety And Security On Campus: Annual Security And Fire Safety Report 2020, University Of Minnesota Morris

Safety and Security Report

No abstract provided.

Sports Science Bachelor's Degree Academic Program Review, 2019, College Of Health, Education, And Human Services, Wright State University

Academic Program Review Reports - All

This report reviews Wright State University's Sports Science Bachelor's Degree program, specifically looking at the time from Fall 2015 to Fall 2019.

Athletic Training Baccalaureate Degree Annual Program Outcomes Assessments, 2019-20, College Of Health, Education, And Human Services, Wright State University

Annual Program Outcomes Assessments - All

This report reviews Wright State University's Athletic Training Baccalaureate Degree program for the 2019-2020 academic year.

Technical Study: Agriculture Associate Degree Annual Program Outcomes Assessments, 2019-20, Lake Campus, Wright State University

Annual Program Outcomes Assessments - All

This report reviews Wright State University's Technical Study: Agriculture Associate Degree program for the 2019-2020 academic year.

Intervention To Influence Healthy Eating Habits Among Dominican University Students: An Examination Of Eating Habits, Kathy Le

Global Public Health | Senior Theses

Food insecurity among college students has become an issue among many universities nationwide. Campus food pantries emerged to combat this problem by providing students with a diverse selection of fresh foods. Most universities are in the pilot process of their food pantries and not many studies have been done to examine the use of healthy ingredients among students. This study included 23 eligible participants who filled out pre- and post-intervention surveys as well as visited the pantry at least once during the intervention stage. The intervention was recipe posters based on the number of ingredients included, difficulty, total preparation and …

Communication Of Professional Readiness In Dietetics And Human Nutrition Undergraduates: A Pilot Study, Heather Norman-Burgdolf, Emily M. Dewitt, Nathan L. Vanderford, Julie Plasencia

Dietetics and Human Nutrition Faculty Publications

Learning experiences within the dietetics and human nutrition undergraduate curricula develop knowledge and skills pertinent to student career goals. Core competency requirements are extensively assessed in these programs, yet the communication of transferable skills gained and student professional readiness are rarely examined. The purpose of this study was to evaluate undergraduate students' perceived professional readiness following six professional development workshops on transferable skills and career preparedness communicated through resumes and personal statements. In this pilot study, twelve upper-level dietetics and human nutrition students self-assessed their resumes and personal statements with rubrics and completed surveys before and after the intervention. Following …

Development Of A Liposomal Formulation For Brain Targeting, Ziru Zhang

Electronic Theses and Dissertations

The blood-brain barrier (BBB), formed by the endothelial cells of the brain capillaries, inhibits the penetration of many therapeutic compounds into the brain. Liposomes, which have unique physicochemical characteristics, have been widely investigated for the drug delivery system across BBB. In the current study, FITC-dextran was used as a model drug that encapsulated in a liposomal formulation to investigated its ability to overcome the blood-brain barrier for targeted brain delivery of therapeutic agents. Here, non-targeted liposome (NT LPs) and RVG-modified liposome (RVG LPs) were prepared. The NT LPs and RVG LPs were about 97 and 101 nm in diameter with …

Role Of Insulin-Like Growth Factor 1 Receptor In The Regulation Of Astrocyte Structure, Function And Cognition, Disha Prabhu

Electronic Theses and Dissertations

Levels of Insulin-like growth factor I (IGF-1) are reduced in several neurological disorders, including aging and neurodegeneration. Aged animals have reduced IGF1 signaling and exhibit impairment in cognition. Supplementing rodents with IGF-1 reverses some of the cognitive deficit, suggesting that IGF-1 signaling could potentially be targeted to ameliorate cognitive decline in older adults. For this, a thorough understanding of the mechanisms by which IGF-1 regulates the function of various cell types in the brain is needed. A majority of studies have focused on the effects of IGF-1 regulating neurons. However, astrocytes that form roughly about 40% of brain mass also …

Toward An Interspecies Right To Breastfeed, Mathilde Cohen

Animal Law Review

Milk is young mammals’ primary food. Yet, lactating animals raised for their milk, such as cows and goats, are subject to extreme forms of violence and control preventing them from breastfeeding their own young. Numerous human parents also lack the legal, economic, social, and emotional support they need to nurse their children. At one level, the situation of humans and that of farmed animals is incommensurable in that the latter’s reproductive and lactating capacity is typically exploited and rewarded by death when unprofitable. At another level, lactating animals of all species are in a related social status. Lactating parents, typically …

The Journal Of Undergraduate Research: 2019

The Journal of Undergraduate Research

This is the complete issue of the South Dakota State University Journal of Undergraduate Research, Volume 17.

Treatment Plans For Diabetes Management During Hurricane Maria In Puerto Rico, Joel De La Cruz Oller

Walden Dissertations and Doctoral Studies

The purpose of this study was to evaluate the health outcomes of diabetic patients in Puerto Rico, before, during, and after Hurricane Maria, in 2017. The Department of Health in Puerto Rico provided the secondary data for the variables low-density lipoproteins (LDL) cholesterol, hemoglobin A1C (HbA1c), mortality, and consumer price index (CPI). The inclusion criteria were participants for whom electronic data were available before, during, and after Hurricane Maria; the sample size was 450. The theoretical framework for this investigation was the health outcomes and impact assessment. The data were analyzed by univariate and analysis of variance (ANOVA) to compare …

Gratitude Among Mothers Raising A Child With Special Health Care Needs, Keli Jean Kleindorfer

Walden Dissertations and Doctoral Studies

For a mother raising a child with special health care needs (CSHCN), maintaining positive feelings of gratitude can become challenging because of the stress associated with caregiving, as well as the consequences of unmanaged stress, which include decreases in both physical and psychological health and well-being. Chronic, unmanaged stress has been associated with various health issues that can be severe and potentially life-threatening. The purpose of this phenomenological study was to examine how mothers raising a CSHCN experience gratitude. A secondary purpose was to identify possible barriers to experiencing gratitude, which, when implemented as a coping style, may decrease the …