Digital Commons Network^™

Mental Health Policy In Vermont Middle Schools, Johanna Arnott

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Alkalinizing Agents: A Review Of Prescription, Over-The-Counter, And Medical Food Supplements., Karen L. Stern, Noah Canvasser, Michael Borofsky, Vanessa M. Gleason, Guido Kamphuis, Marawan M. El Tayeb, Ryan Hsi, Kymora B. Scotland

Jefferson Hospital Staff Papers and Presentations

Introduction

Kidney stones affect 1 in every 11 people in the United States each year. There is a significant high recurrence rate without a stone prevention protocol. Alkali citrate is beneficial in decreasing stone recurrence, but due to the cost and gastrointestinal side effects there is a low adherence rate. This study aims to serve as a review of some of the most commonly used alkalizing over‐ the‐ counter supplements that are advertised to prevent and treat kidney stones.

Methods

Data was gathered by a comprehensive online literature search and company inquiries for kidney stone prevention supplements. An additional informal …

The Potential Ergogenic Effects Of Cbd And How The Ecs Combats Performance Deficits From Overtraining, Jeremy Park

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Community Gardens: Food Security And Cultural Preservation, April Hill

Renée Crown University Honors Thesis Projects - All

No abstract provided.

Myoglobin Post-Translational Modifications And Fresh Beef Color Stability, Yifei Wang

Theses and Dissertations--Animal and Food Sciences

Surface color of fresh beef is the major trait influencing consumers’ purchase decisions. Fresh beef color is determined by the myoglobin (Mb) redox stability. Post-translational modifications (PTMs) play a critical role in regulating Mb structure and functionality. This thesis focuses on the PTMs in Mb and their impact on fresh beef color stability.

In the first experiment, Mb PTMs in beef longissimus lumborum (LL) muscle during postmortem aging and their influence on fresh beef color stability were examined. Beef LL muscle from nine (n = 9) beef carcasses (24 h postmortem) were subjected to wet-aging for 0, 7, 14 …

Beyond Good Intentions: New Legislation On Foreign Aid Effectiveness

The International Lawyer

The new law and the corresponding OMB and key foreign aid agencies' guidelines require providers to follow best practices in the monitoring and evaluation (M&E) of U.S government (USG) foreign aid.2 A recent study conducted by the U.S. Government Accountability Office across the key USG foreign aid agencies identified a number of areas that needed improvement in the design, implementation, conclusions, and dissemination of foreign assistance evaluations.3 FATAA and the relevant guidelines will require providers to address those areas and focus their reporting requirements on tangible outcomes and the impact of their programming. In recent years, federal agencies have placed …

Single-Arm, Non-Randomized, Time Series, Single-Subject Study Of Fecal Microbiota Transplantation In Multiple Sclerosis, Phillip A. Engen, Antonia Zaferiou, Heather Rasmussen, Ankur Ankub, Stefan J. Green, Louis F. Fogg, Christopher B. Forsyth, Shohreh Raeisi, Bruce Hamaker, Ali Keshavarzian

Department of Nutrition and Health Sciences: Faculty Publications

Emerging evidence suggests intestinal microbiota as a central contributing factor to the pathogenesis of Relapsing-Remitting-Multiple-Sclerosis (RRMS). This novel RRMS study evaluated the impact of fecal-microbiota-transplantation (FMT) on a broad array of physiological/clinical outcomes using deep metagenome sequencing of fecal microbiome. FMT interventions were associated with increased abundances of putative beneficial stool bacteria and short-chain-fatty-acid metabolites, which were associated with increased/improved serum brain-derived-neurotrophic-factor levels and gait/walking metrics. This proof-of-concept single-subject longitudinal study provides evidence of potential importance of intestinal microbiota in the pathogenesis of MS, and scientific rationale to help design future randomized controlled trials assessing FMT in RRMS patients.

An Overview On Chemotherapy-Induced Cognitive Impairment And Potential Role Of Antidepressants, Ankit Das, Niraja Ranadive, Manas Kinra, Madhavan Nampoothiri

Open Access archive

Background: Cognitive impairment is an adverse reaction of cancer chemotherapy and is likely to affect up to 75% of patients during the treatment and 35% of patients experience it for several months after the chemotherapy. Patients manifest symptoms like alteration in working abil-ity, awareness, concentration, visual-verbal memory, attention, executive functions, processing speed, fatigue and behavioural dysfunctions. Post-chemotherapy, cancer survivors have a reduced quality of life due to the symptoms of chemobrain. Apart from this, there are clinical reports which also associate mood disorders, vascular complications, and seizures in some cases. Therefore, the quality of lifestyle of cancer patients/ survivors is …

Assessment Of Monoamine Neurotransmitters In The Cortex And Cerebellum Of Gamma-Irradiated Mice: A Neuromodulatory Role Of Cynodon Dactylon, Roopesh Poojary, Nayanatara Kumar, Reshma Kumarchandra, Ganesh Sanjeev

Open Access archive

INTRODUCTION: Radiation is an important tool in the diagnostic and curative treatment of many cancers. Ionizing radiation induces many biochemical changes in the cells. The present study was designed to estimate the level of neurotransmitters in the distinct brain tissue of Swiss albino mice before exposing gamma radiation. MATERIALS AND METHODS: The mice were treated with 0.25 and 1 g/kg body weight of Cynodon dactylon extract (CDE) via oral gavage for 7 days and subjected to 5 Gy of gamma radiation. The estimation of monoamines was performed in the cortex and cerebellum separately. RESULTS: Mice exposed to a sublethal dose …

Micronutrients Status Among Human Immunodeficiency Virus-Infected Children In Southern India, Sangeetha Sivasubramanian, Janardhan Shenoy, Sowmini P. Kamath, Vaman Kulkarni

Open Access archive

Introduction: Deficiencies of micronutrients play a role in human immunodeficiency virus (HIV) infection and its severity. Identifying the micronutrient status would guide supplementation, thus altering the disease progression and severity. Material and methods: A cross-sectional hospital-based study was conducted in Southern India on hundred HIV-infected children. Estimation of serum micronutrient levels (zinc, copper, and iron) and comparison of the deficient micronutrients with clinical stages, immunological categories, CD4 counts, and nutritional status was performed. Results: Among 100 HIV-infected children, zinc deficiency was the most common (62%), whereas copper and iron deficiency was present in 2% and 1%, respectively. Mean age of …

Assessment Of Association Between Antihypertensive Drug Use And Occurrence Of New-Onset Diabetes In South Indian Patients, Sneha Sabu, Shubha Seshadri, Girish Thunga, Pooja Poojari

Open Access archive

Objective: The objective of this study was to determine the association between antihypertensive drug use and new-onset diabetes (NOD) in patients with hypertension (HTN). Materials and Methods: A retrospective observational study was conducted in a tertiary care hospital located in south India. Patients diagnosed with HTN and HTN with diabetes between January 2012 and December 2016, were identified and studied. Medical records of these patients from Medical Record Department were evaluated by medical record review method, and relevant data were recorded in a case record form. Statistical evaluation by chi-square method and odds ratio (OR) was carried out to appraise …

Time-Restricted Feeding Extends Longevity In Drosophila Melanogaster, Daniel Cabrera

Student Theses and Dissertations

Time-restricted feeding (TRF) is a dietary intervention in which daily feeding patterns align with behavioral patterns, synchronizing feeding times with periods of higher activity, e.g. humans eating only during the day or rodents (nocturnal animals) at night. TRF has been shown to improve cardiac health in Drosophila melanogaster, reduce metabolic markers in rodent models, and reduce glycemic indices in prediabetic men. However, the mechanism and long-term effects of this intervention remain elusive. To understand the effect of TRF on longevity we used the fruit fly Drosophila melanogaster, which is a useful model for longevity, sleep and circadian studies because of …

Sympathy For The Microbiota: How Changes In Gut Microbial Composition Influence The Immune System And Basic Physiology By Way Of The Sympathetic Nervous System, Paul Andrew Muller

Student Theses and Dissertations

The gastro-intestinal tract is the most extensive mucosal surface in mammals and harbors the most numerous immune cell reservoir as well as a complex and autonomous nervous system. The GI tract is continuously exposed to foreign antigen and potentially toxic chemicals through the ingestion of food. In addition, the lumen of the human GI tract is populated with approximately 1013 bacteria, which is equivalent to the number of cells in the entire human body (Sender et al., 2016). The intestinal microbiome, which aids in host metabolism, represents a diverse population of microorganisms separated from the inside of the body by …

Regional Geographies Of The Us-Mexico Border, Kimberly Collins, Mike Kohout

Geography and Environmental Studies Faculty Publications

No abstract provided.

Evaluating The Utility Of Diagnostic Workups For Biliary Atresia In Neonates With Cholestatic Jaundice Following Prolonged Tpn, Melissa Austin, Zubair H. Aghai

Phase 1

Introduction: Parenteral nutrition associated cholestasis (PNAC) develops in 40-60% of premature infants following TPN for 2-4+ weeks. The incidence of biliary atresia is low and there is a 60-day, post-term window for corrective surgery. There is limited data on both the natural history of PNAC in premature infants following prolonged TPN, as well as the utility of diagnostic tools investigating biliary atresia in these patients.

Methods: A retrospective chart review using EMR data from the Intensive Care Nursey was performed with the following criteria: premature babies diagnosed with cholestasis, born at <1500 grams, and received TPN for 14 days. Ultimately 61 babies met criteria and data was collected and pooled to produce descriptive statistics and graphs describing laboratory trends.

Results: Median gestational age was 26 [IQR 25, …

Assessment Of Dobhoff Tube Malposition On Radiographs Using Deep Learning, Kevin George, Paras Lakhani, Md

Phase 1

Introduction: Dobhoff tubes (DHT) are narrow-bore flexible devices that deliver enteral nutrition for critically ill patients. Tracheobronchial insertion of DHTs presents a significant risk for pulmonary complications. Thus, DHT insertion requires radiologist confirmation of correct placement with chest x-ray (CXR), increasing clinical delays. To address this, we demonstrate the novel application of Deep Convolutional Neural Networks (DCNNs) to automatically and accurately identify DHTs in CXRs in real time.

Methods: 141 de-identified HIPAA compliant frontal view chest radiographs containing DHTs in various positions were obtained. The DHTs were first manually segmented and verified by a board certified radiologist. Images were split …

Jefferson Digital Commons Quarterly Report: October-December 2019, Kelsey Duinkerken, Msi, James Copeland, Libt, Larissa Gordon, Mslis, Med, Ma

Jefferson Digital Commons Reports

This quarterly report includes:

• Articles
• Dean's Research Development Lunch Conference
• Dissertations
• Educational Materials
• From the Archives
• Grand Rounds and Lectures
• Journals and Newsletters
• Population Health Presentation Materials
• Posters
• Reports
• Symposiums
• What People are Saying About the Jefferson Digital Commons

Public Health Bachelor's Degree Academic Program Review, 2019, College Of Science And Mathematics, Wright State University

Academic Program Review Reports - All

This report reviews Wright State University's Public Health Bachelor's Degree program, specifically looking at the time from Fall 2015 to Fall 2019.

The Effect Of Advanced Glycation End Products (Ages) On Macrophages, And Their Implications For Prostate Cancer Progression, Callan C. Frye

MUSC Theses and Dissertations

Advanced glycation end products (AGEs) are sugar-protein adducts that may worsen cancer severity and may contribute to health disparity outcomes among prostate cancer (PCa) patients. AGEs are formed endogenously via a slow, nonenzymic reaction; however, AGEs are also formed in foods as a result of subjecting meats and sugars to high-heat conditions. AGEs are therefore prolific in the Western Pattern Diet (WPD), which has become increasingly common among industrialized nations. Previous work has identified dietary AGE as contributing to MYC-driven PCa progression, and the dependence of this process upon stromal receptor for advanced glycation end products (RAGE). This study therefore …

Medical Utilization In The Context Of Culture: Analyzing The Concepts, Benefits And Drawbacks Of Sri Lankan Biomedical And Ayurvedic Healthcare, Miriah Rajaguru

All Graduate Theses, Dissertations, and Other Capstone Projects

Sri Lanka is an island inhabited by a culture more than 5,000 years old. The primary medicine utilized by this culture in precolonial times is known as Ayurveda. During colonization, Sri Lanka was introduced to biomedicine and forced to negate Ayurvedic medicine. Throughout the years, rather than abandoning their indigenous medical practice, Sri Lanka incorporated biomedicine and Ayurvedic medicine into their medically plural society. Today, Sri Lankans utilized both medicines for different ailments, concerns and conditions. Utilizing a variety of anthropological methods and theories, this study gathered qualitative information from 39 Sri Lankan informants. These informants were recruited to find …

Comparison Of Minnesota Teachers’ Sex Education Instructional Practices With Professional Preparation And Development, Lisa Brichacek

All Graduate Theses, Dissertations, and Other Capstone Projects

Nationally, many health teachers have not received health education training. Minnesota does not require sexual health training or sexual health professional development for health education teachers. School Health Profiles 2018 data was analyzed to determine who teaches sexual health education in Minnesota, what they teach, how they teach it, and their desired future professional development. Teachers who received pre-service health education training were compared with teachers who received other pre-service preparation. Additionally, teachers who received sexual health professional development were compared with teachers who did not receive sexual health professional development. Data analyses included crosstabs with Phi and Cramer’s V …

The Impact Of Cooking Groups On One Individual's Transition To Independent Living, Alison Garcia

Occupational Therapy Doctorate Capstone Projects

The goal of occupational therapy in inpatient psychiatric settings is to develop independent living skills and restore normative life roles vital for leading a fulfilling life in the least restrictive environment. In one psychiatric hospital, cooking groups are an essential intervention and environment in which to develop these skills and roles. The purpose of this qualitative case study is to describe OT cooking group programing in one inpatient psychiatric setting, understand one client’s experience with cooking groups and illustrate how her participation in these groups led to a successful transition to independent living. This study was guided by the transformative …

Articulator Q1 2020

Metro Denver Dental Society Articulator Magazine

The MDDS Articulator magazine has been serving as the voice for Denver's dental community for over 100 years.

Distributed to approximately 2,000 dental professionals quarterly, the Articulator features local news, industry trends, practice management guidance, data-driven research and more. The award-winning publication is available to member dentists in both print and digital forms.

Issues include cover and feature articles alongside regular columns with regional news impacting the Metro Denver membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Telehealth Efforts To Reduce Hospital Readmissions Of Congestive Heart Failure Patients, Sirfornia L. Deasfernandes

Walden Dissertations and Doctoral Studies

Congestive heart failure (CHF) is a chronic condition that affects millions of individuals in the United States. There is no cure for CHF, but medical interventions can help treat the symptoms and improve health outcomes. The purpose of this quantitative study was to determine if telehealth services help to reduce the readmission status of patients diagnosed with CHF. The theoretical framework used in this study was the individual and family self-management theory to help focus on self-management behaviors that contribute to improving the patients' health outcomes. The research questions were focused on addressing CHF patients receiving telehealth services and whether …

The Effects Of A Plant-Based Diet On Inflammation Of Patients With Cardiac Disease, Rachel L. Butcher

Honors Undergraduate Theses

Cardiac disease is the primary cause of death in the United States of America (CDC, 2017). Despite ongoing efforts and investments to improve cardiac health in the United States, most of the population will suffer from cardiovascular diseases. There is a multitude of research supporting that diet can contribute to cardiac disease, but it is less known that diet can greatly contribute to regulation and reversal of cardiovascular disease processes (Huang et al., 2012; Satija et al., 2017; Kim et al., 2019). Existing research supports the efficacy of plant-based diets to manage and reverse certain cardiac diseases (Tuso et al., …

Trophic Enteral Feeds In Mechanically Ventilated Adult Patients With Acute Respiratory Distress Syndrome/Acute Lung Injury And Associated Clinical Outcomes, Kiersten Ann Tidwell

Honors Undergraduate Theses

Enteral nutrition (EN) is often delayed in critically ill patients despite strong evidence to support that early enteral nutrition feeding is beneficial in this population. Adverse outcomes in critically ill patients in which nutrition is delayed include a longer length of stay and time on the ventilator, and a higher incidence of pneumonia and hospital mortality. The purpose of this literature review was to evaluate the current evidence regarding trophic enteral feeds in mechanically ventilated adult patients with acute respiratory distress syndrome (ARDS)/acute lung injury (ALI) and associated clinical outcomes. A retrospective literature review was performed to identify articles published …

Analysis Of Small Rna Populations Generated In Peanut Leaves After Exogenous Application Of Dsrna And Dsdna Targeting Aflatoxin Synthesis Genes, Imana L. Power, P. C. Faustinelli, Valerie Orner, Victor S. Sobolev, Renee S. Aria

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Previously, we have shown that RNA interference (RNAi) can prevent aflatoxin accumulation in transformed peanuts. To explore aflatoxin control by exogenous delivery of double-strand RNA (dsRNA) it is necessary to understand the generation of small RNA (sRNA) populations. We sequenced 12 duplicate sRNA libraries of in-vitro-grown peanut plants, 24 and 48 h after exogenous application of five gene fragments (RNAi-5x) related to aflatoxin biosynthesis in Aspergillus flavus. RNAi-5x was applied either as double-stranded RNA (dsRNA) or RNAi plasmid DNA (dsDNA). Small interfering RNAs (siRNAs) derived from RNAi-5x were significantly more abundant at 48 h than at 24 h, and the …

Spices, Spirituality, And Scarcity: Experiences Of Food And Drink In The Middle Ages, Thomas Nelson

History - Master of Arts in Teaching

I. Synthesis Essay………………………….......3

II. Primary Documents and Headnotes………27

III. Textbook Critique…………………………...37

IV. New Textbook Entry………………………...40

V. Bibliography…………………………………..49

Prekindergarten Educators' Perspectives On Professional Development About Transgender And Gender-Nonconforming Children, Danita Marie Norris Mccray

Walden Dissertations and Doctoral Studies

Young children start to develop an understanding of gender and gender identity in prekindergarten. Early childhood educators require professional development in creating safe, supportive learning environments for transgender and gender nonconforming children. Limited research has focused on prekindergarten educators' knowledge, skills, and dispositions about supporting transgender and gender nonconforming children in their classrooms. Framed by Bronfenbrenner’s bioecological systems theory and Derman-Sparks antibias early childhood concepts, the purpose of this basic qualitative study with interviews was to explore prekindergarten educators' perspectives on professional development about transgender and gender nonconforming children. Data were collected using semistructured, in-depth interviews with 12 prekindergarten educators …

Association Of Social Support And Depressive Symptoms Among African Americans, Jacketta Renee Cobbs

Walden Dissertations and Doctoral Studies

Depression affects over 120 million individuals worldwide; in the United States, depression is a leading cause of disability for individuals’ ages 15-44 years. Social support can affect both physical and depressive symptoms; therefore, most patients with heart failure (HF) need support from family and/or friends to effectively manage their health condition. This indicates family and/or friends are expected to be the core support system for long term care of those with HF. The purpose of this study was to determine whether social support contributes to depressive symptoms among African Americans with HF. The research questions examined the experience of different …