Digital Commons Network^™

Complete Response To Stage Iv Colorectal Adenocarcinoma With Disease-Free Survival At 24 Months: Case Report And Overview Of The Literature, Madison N. Crank 6746693, Arslan Iqbal, Michael Abdelmasseh, Mohamed Alsharedi, Doreen Griswold, Alysia Browne, Juan R. Sanabria

Marshall Journal of Medicine

Over 150,000 new cases of colon cancer were diagnosed in the US in 2019. Stage and age at diagnosis are important prognostic factors for overall survival (OS). For the age group 70-79, the OS for females with poorly differentiated stage IV colon cancer at 1, 2 and 5 years after surgery is 39%, 15%, and 2%, respectively. We present a case of a 77-year-old female with significant cardiac history. She was diagnosed with stage IV colorectal cancer complicated with enteric fistula. Due to her initial performance status and comorbidities, she was not a candidate for surgery or systemic chemotherapy. Nonetheless, …

Transitioning To Value-Based Diabetes Care: A Call For Action Derived From Primary Care Providers In South Florida, Francois Sainfort, Julie A. Jacko, Johannes Vieweg

HCA Healthcare Journal of Medicine

Background: In Florida, 2.4 million people have diabetes and 5.8 million are pre-diabetic. Not only has the prevalence of diabetes doubled over the past 20 years from 5.2 in 1992 to 11.2 in 2014, but the Centers for Disease Control and Prevention expects 1 out of every 3 adults will have diabetes by the year 2050. In addition, in every year since 1996, Florida well exceeds the national levels in terms of prevalence of diabetes, and the gap is getting wider. A study was conducted to gather information from key physician stakeholders as to how to address unmet needs of …

The Role Of Nutrition In Promoting Gut Health And Treating Chronic Illness Through The Attenuation Of Inflammation, Allison Dalton

HCA Healthcare Journal of Medicine

Over the millennia, the human body and microorganisms such as bacteria, viruses, archaea, protozoa and parasites have coevolved together forming an intimate relationship. These microorganisms are found on the skin, in the mouth, genitourinary tract and most abundantly in the large intestine of the digestive tract. States of microbial dysbiosis contribute to chronic inflammation, which can lead to the pathogenesis and progression of numerous diseases. Micro- and macro-nutrients as well as dietary patterns like the Mediterranean diet can help improve health outcomes.

Producer Willingness To Pay For Enhanced Packaging To Prevent Postharvest Decay Of Strawberries, Brian Coffey, Valentina Trinetta, Londa Nwadike, Umut Yucel

Journal of Applied Farm Economics

We surveyed specialty crop producers in Kansas and Missouri to determine producer willingness to pay for new active packaging technology that prevents postharvest loss and increases shelf life. The survey also asked demographic questions to determine the producer and operation traits for this growing segment of production agriculture. More than half of those surveyed were female, and 60% were under 50 years of age. Smaller operations tend to utilize direct marketing and social media activity more than larger operations. Parametric willingness to pay estimates are approximately $0.39 per cardboard flat to purchase the antifungal film that increases shelf life of …

Improving Beef Cattle Profitability By Changing Calving Season Length, Christopher N. Boyer, Andrew P. Griffith, Ky G. Pohler

Journal of Applied Farm Economics

We determined the impacts of calving season length on net returns and variability in net returns for spring-and fall-calving herds in Tennessee. Weaning weight as a function of calving date was estimated using a 19-year data set and simulation models generated distributions of net returns for 45-, 60-, and 90-day calving periods with and without using hypothetical improved reproductive management (IRM) practices. Shortening the calving period from 90 days increased expected net returns in the spring-and fall-calving herds. The 45-day fall-calving period with IRM maximized profits, but an extremely risk-averse producer would select a 45-day fall-calving period without IRM.

Cplr And Water Resource Utilization By Livestock Farmers In Different Ecosystems Of India, Purushottam Sharma, Sadhna Pandey, R. K. Sharma, J. P. Upadhyay, Satyapriya, A. K. Ray, Nagaratna Biradar, S. Radotra

IGC Proceedings (1977-2023)

The common property resources comprises of all such resources that are meant for common use of the villagers including all resources. The National Sample Survey Organization (NSSO), 1999 in its report defines CPRs as “Resources accessible to and collectively owned\held\managed by an identifiable community and on which no individual has exclusive property rights are called common property resources”. Over the time, there has been gradual decline in CPRs availability to the villagers. The CPRs play an important role in the livelihood of resource poor farmers. According to NSSO, 1999, the percentage of Common Property Land Resources in total geographical area, …

Vol.47 N.41 April 30th 2020, Voice Media Ventures

Black Voice News

No abstract provided.

Examining Changes In Bat Swing Kinematics In Different Areas Of The Strike Zone In Collegiate Baseball Players, Charles C. Williams, Paul T. Donahue, Samuel J. Wilson, James Grant Mouser, Christopher M. Hill, Lauren A. Luginsland, Jacob Gdovin, Chip Wade, John C. Garner

College of Health and Human Services

No abstract provided.

Qualitative Thematic Analysis Of Social Media Data To Assess Perceptions Of Route Of Administration For Antiretroviral Treatment Among People Living With Hiv, Louis S. Matza, Trena Paulus, Cindy P. Garris, Nicolas Van De Velde, Vasiliki Chounta, Kristen A. Deger

ETSU Faculty Works

Background: HIV is a condition that requires lifelong treatment. Treatment options currently consist of oral antiretroviral therapies (ART) taken once or twice daily. Long-acting injectable HIV treatments are currently in development to be administered monthly or every other month. Preferences for route of administration could influence treatment adherence, which could affect treatment outcomes. The purpose of this study was to examine patient perceptions of oral and injectable routes of administration for ART.

Methods: Qualitative thematic analysis was conducted to examine 5122 online discussion threads by people living with HIV (PLHIV) in the POZ Community Forums from January 2013 …

Examination Of Parasite Assemblages In Killifish Of The Genus Fundulus Across The Atlantic Coast Of The United States And Canada, Derek Garvey

HCNSO Student Theses and Dissertations

Killifish of the genus Fundulus were examined to assess the factors shaping parasite community structure at a genus level. A database of previous parasite surveys on Fundulus species across the Atlantic coast of the United States and Canada was created from a literature review. The database included parasite and environmental factor data from 15 sources. Additional sites from New Brunswick, Maine, Massachusetts, Rhode Island, North Carolina, and South Carolina were sampled for Fundulus species. The resulting database includes data for 10 species from a total of 57 unique geographic sites. Data on the diversity and abundance of metazoan parasites were …

Genetic Intelligence: Myth Busted, Carissa Brand

Academic Symposium of Undergraduate Scholarship

No abstract provided.

Validity And Reliability Of Three Commercially Available Smart Sports Bras During Treadmill Walking And Running, James W. Navalta, Gabriela Guzman Ramirez, Crystal Maxwell, Kara N. Radzak, Graham R. Mcginnis

Kinesiology and Nutrition Sciences Faculty Research

A variety of wearable technology devices report heart rate. Heart rate sensing smart bras are manufactured for females who participate in activity, however accuracy has not been determined. The purpose was to determine the validity of heart rate measures in three commercially available sports bras during walking and running. Twenty-four healthy females completed bouts of treadmill exercise. The Adidas Smart sports bra, Berlei sports bra, and Sensoria Fitness biometric sports bra were tested. Participant perception of each garment was obtained immediately after the participant divested the sports bra. The Adidas Smart sports bra was valid only during rest (Intraclass correlation …

The Weekly Challenger, April 30, 2020, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The April 30, 2020, issue of The Weekly Challenger.

Qualitative Observations Of Successful Spawning By Two Species Of Small-Bodied Minnows Following Pit Tagging, Casey A. Pennock, Lindsey A. Bruckerhoff

Western North American Naturalist

PIT tags are a common tool used to identify and track movements of fishes. Although technological advances facilitated the use of PIT tags across a wide range of fish body sizes, we do not yet fully understand the effects of PIT tagging on basic aspects of many species’ life histories (e.g., survival, spawning success, or reproductive output). We observed 2 small-bodied fishes, Red Shiner (Cyprinella lutrensis) and Bluntnose Minnow (Pimephales notatus), achieve successful spawns after PIT tagging. Age-0 fish of both species were observed in multiple experimental stream units during an outdoor mesocosm study in which …

An Analysis Of Crispr-Cas Gene Editing In Agriculture, Ashley Laliberte

Honors Scholar Theses

The CRISPR-Cas system is a promising form of gene editing, especially for the agriculture industry. The ability to make single-nucleotide edits within a gene of interest, without the need to introduce foreign DNA, is a powerful tool for designing healthier and more efficient crops and food animals. This system provides opportunity for increased nutritional value, decreased food waste, and more economically and environmentally sustainable food production. Though this biotechnology is facing mechanistic limitations due to off-target effects and inefficient homology-directed repair, vast improvements have already been made to improve its efficacy. The CRISPR-Cas system is already the most advanced form …

Breastfeeding Or Formula Feeding: A Mother's Choice, Trista Briggs, Mateja R. Savoie-Roskos, Lydia Bangerter, Casey Coombs

All Current Publications

Deciding how to feed an infant is a decision that should be made by a mother and her family. The benefits of exclusively breastfeeding an infant for the first six months of life are well established (World Health Organization [WHO], 2017); however, it may not always be feasible or a preferred option. For mothers who cannot or choose not to breastfeed, formula feeding is a great option that can support a healthy and thriving infant. This fact sheet will address common questions about breastfeeding and formula feeding to help mothers make an informed decision on how to feed their infant, …

The Precise (Pregnancy Care Integrating Translational Science, Everywhere) Network’S First Protocol: Deep Phenotyping In Three Sub-Saharan African Countries, Peter Von Dadelszen, Meriel Flint-O’Kane, Lucilla Poston, Rachel Craik, Donna Russell, Rachel M. Tribe, Umberto D’Alessandro, Marleen Temmerman, Angela Koech, Anna Roca

Obstetrics and Gynaecology, East Africa

Background: The PRECISE (PREgnancy Care Integrating translational Science, Everywhere) Network is a new and broadly-based group of research scientists and health advocates based in the UK, Africa and North America.

Methods: This paper describes the protocol that underpins the clinical research activity of the Network, so that the investigators, and broader global health community, can have access to ‘deep phenotyping’ (social determinants of health, demographic and clinical parameters, placental biology and agnostic discovery biology) of women as they advance through pregnancy to the end of the puerperium, whether those pregnancies have normal outcomes or are complicated by one/more of the …

Legal Issues On Indonesian Marine Plastic Debris Pollution, Zhen Jing, Sutikno Sutikno

Indonesia Law Review

Various problems related to marine plastic debris pollution have yet to be resolved. Therefore, the definition, categorization, origin, and degradation of marine plastic debris must be thoroughly investigated to gain a comprehensive understanding of the related issues. The presence of marine plastic debris has significant implications on marine environments, including ecological, biodiversity, health, and economic impacts. Marine plastic debris originates from both landand ocean-based sources, and there have been efforts to prevent or reduce its introduction and accumulation in the marine environment. In Indonesia, such a problem must be solved through the implementation of more effective, efficient, and specific regulations, …

May 7, 2020: Agenda, University Of North Dakota

University Senate Meeting Minutes

Agenda for the May 7, 2020, meeting of the University Senate. 106 pages

The Effects Of The Omega-3 Fatty Acids Docosahexaenoic Acid On Inm1 Gene Expression In Saccharomyces Cerevisiae, Haley Kang

Honors Theses

Bipolar disorder is a mental disorder associated with abnormal inositol levels. Preliminary studies show omega-3 fatty acids alter intracellular inositol levels; however, the cellular mechanism behind this process is unknown. Therefore, the focus of this study is to determine the effects of the omega-3 fatty acid docosahexaenoic acid (DHA) on the expression of INM1 which encodes inositol monophosphatase. Using yeast as our model system, cells were grown in varying concentrations DHA and the expression on INM1 was determined by RT-qPCR. The results show INM1 expression increased with increasing concentrations of DHA; thus, the effects of DHA on inositol levels may …

Profil Terapi Antihipertensi Dan Antihiperlipidemia Terhadap Fungsi Ginjal Pasien Diabetes Melitus Tipe 2 Dengan Komplikasi Penyakit Ginjal Kronis Di Rsup Dr. Hasan Sadikin, Fitri Rachmaini, Lia Amalia, Cherry Rahayu

Pharmaceutical Sciences and Research

Chronic Kidney Disease (CKD) complication increases the risk of morbidity and mortality in type 2 diabetes mellitus (DMT2) patients. The presence of hypertension and dyslipidemia as comorbidity increases the risk of macrovascular and microvascular complications and further adding to the list of drugs used. Management of this comorbidity is essential to prevent cardiovascular events and minimize kidney damage. This study aimed to evaluate therapeutic profile of antihypertensive and antihyperlipidemia drugs towards kidney function in DMT2 patients with CKD complication at Dr. Hasan Sadikin Hospital. Study was done by using a prospective single cohort design with consecutive sampling technique and obtained …

The Contribution Of Qualitative Research Within The Precise Study In Sub-Saharan Africa, Marina A. S. Daniele, Melisa Martinez-Alvarez, Angela Koech, Marianne Vidler, Tatiana Salisbury, Prestige Tatenda Makanga, Peris Musitia, Meriel Flint-O’Kane, Tanya Wells Brown, Brahima Amara Diallo, Marleen Temmerman, Geoffrey Omuse, Sikolia Wanyonyi, Patricia Okiro

Obstetrics and Gynaecology, East Africa

The PRECISE Network is a cohort study established to investigate hypertension, fetal growth restriction and stillbirth (described as “placental disorders”) in Kenya, Mozambique and The Gambia. Several pregnancy or birth cohorts have been set up in low- and middle-income countries, focussed on maternal and child health. Qualitative research methods are sometimes used alongside quantitative data collection from these cohorts. Researchers affiliated with PRECISE are also planning to use qualitative methods, from the perspective of multiple subject areas. This paper provides an overview of the different ways in which qualitative research methods can contribute to achieving PRECISE’s objectives, and discusses the …

The Zircon, April 31, 2020 [Spoof Issue], Dordt University

Dordt Diamond

No abstract provided.

Development Of Ethanolic Extract Of Pinang Masak Jambi (Areca Catechu L.) As A Modulator Of Doxorubicin Cytotoxic Effect In Breast Cancer Therapy, Fitrianingsih Fitrianingsih, Indri Maharini, Diah Tri Utami

Pharmaceutical Sciences and Research

Doxorubicin is one of the chemotherapy agents that is often used in breast cancer therapy. Phenomenon of breast cancer cell resistance to chemotherapy agents has been traced to the molecular level. The development of compounds that can overcome drug resistance chemotherapy needs to be continuously developed, especially agents with specific molecular targets, namely P-glycoprotein (Pgp), NFkB, cyclin, and cyclin-dependent kinase (CDK). Another alternative is the combination of chemotherapy agents with chemopreventive agents (co-chemotherapy) to reduce side effects and increase sensitivity of cancer cells. Doxorubicin is often used in breast cancer therapy. This study was performed to determine the effect of …

Legalization Of Abortion Against Victims Of Rape Crimes Viewed From Victimology Perspective, Siska Elvandari

Jurnal Hukum & Pembangunan

One of human rights guaranteed and protected in the 1945 Constitution is the right to live and maintain life, stated in Article 28 A of the 1945 Constitution. The right to live and maintain life is the highest right that is inherent in human beings as the subject of law since humans were born to death in the world. The right to live and maintain life is not only inherent in human beings who have been born, but also in humans or children who are still in the womb, stated in Article II of the Civil Code that "Children are …

If A Fetus Is A Person, It Should Get Child Support, Due Process, And Citizenship, Carliss N. Chatman

Washington and Lee Law Review Online

This Article was originally published in The Washington Post on May 17, 2019. It has been edited and updated prior to its publication in the Washington and Lee Law Review.

Alabama has joined the growing number of states determined to overturn Roe v. Wade by banning abortion from conception forward. The Alabama Human Life Protection Act subjects a doctor who performs an abortion to as many as ninety-nine years in prison. The law has no exceptions for rape or incest. It redefines an “unborn child, child or person” as “[a] human being, specifically including an unborn child in utero …

Do Lactic Acid Bacteria In Fermented Foods Persist In The Gastrointestinal Tract: An In Vitro Investigation, Chloe M. Christensen, Car Reen Kok, Robert W. Hutkins

UCARE: Research Products

It is now well established that the composition of the gastrointestinal (GI) microbiota has a profound influence on intestinal and overall health. Many contemporary diseases such as type two diabetes, IBS and obesity are associated with a dysbiotic microbiota. Therefore, researchers are interested in how diet and specific dietary components can modulate the gastrointestinal microbiota and possibly repair a dysbiotic state. One approach to improve gastrointestinal health is by consuming probiotics and prebiotics or a diet rich in fermented foods containing live microbes. Fermented foods are popular because of their enhanced preservation, safety, organoleptic, functionality, and nutritional properties. These fermented …

Zika Virus Induces Apoptosis In Retinal Pigmented Epithelial Cells, Madison Kraus, Philma Glora Muthuraj, Sathish Kumar Natarajan

UCARE: Research Products

Zika virus is a single-stranded positive sense RNA virus that attracted international attention in 2015 when an epidemic broke out in Brazil. This vector borne virus is transmitted by mosquitos and is especially concerning for pregnant women because the virus can affect the development of the fetus. One known complication is the destruction of infected retinal epithelial cells. The transduction of light is interrupted due to cell death and results in blind spots. Previous research has demonstrated that palmitoleate can reduce the observed levels of apoptosis in ZIKAV infected JEG-3 cells. We have also seen the protection of retinal pigmented …

The Precise (Pregnancy Care Integrating Translational Science, Everywhere) Database: Open-Access Data Collection In Maternal And Newborn Health, Laura A. Magee, Amber Strang, Larry Li, Domena Tu, Warancha Tumtaweetikul, Rachel Craik, Marina Daniele, Angela Koech, Umberto D’Alessandro, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

In less-resourced settings, adverse pregnancy outcome rates are unacceptably high. To effect improvement, we need accurate epidemiological data about rates of death and morbidity, as well as social determinants of health and processes of care, and from each country (or region) to contextualise strategies. The PRECISE database is a unique core infrastructure of a generic, unified data collection platform. It is built on previous work in data harmonisation, outcome and data field standardisation, open-access software (District Health Information System 2 and the Baobab Laboratory Information Management System), and clinical research networks. The database contains globally-recommended indicators included in Health Management …

Australia’S Tobacco Plain Packaging Law: An Analysis Of The Trips Article 20 Challenge At The Wto, Cheryl Kirschner

Pace International Law Review

Australia’s Tobacco Plain Packaging Act 2011 (TPP) and corresponding regulations specify that tobacco products be packaged in a particular size box and be made of certain material. No trademark other than the brand’s name may be printed, and font, letter size, color, and other packaging aspects are specified with particularity. These measures recently withstood a contentious dispute settlement request submitted on multiple grounds by four World Trade Organization (WTO) Member countries. What does the WTO’s Panel Report in this case tell us about the extent to which a country can take measures to advance its public health initiatives without violating …