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George Peter Mwanza And Melvin Beene V Attorney General Appeal No. 153/2016 Sc Selected Judgment No. 33 Of 2019, Ellah T.M. Siang’Andu

SAIPAR Case Review

On the 9th December 2019, the Supreme Court of Zambia delivered a landmark decision changing the human rights jurisprudence in the context of protecting and preserving the fundamental human rights of prisoners. The appellants were HIV positive and were both in custody at the Lusaka Central Prison. They petitioned the High Court contending breach of their rights to life and protection from inhuman treatment contrary to the Republican Constitution. The argument of the appellants was that the State’s failure to consider their dietary and health needs, due to the budgetary and logistical restraints, fell short of all prescribed standards for …

Evaluating The Clinical Impact Of Providing Home Blood Pressure Monitors To Patients With Elevated Or High Blood Pressure, Theresa La Guardia Asmus

Doctoral Projects

Many clinicians continue to diagnose hypertension based on office-based readings, despite the 2015 United States Preventive Services Task Force recommendation for the use of home or ambulatory blood pressure monitoring to confirm the diagnosis of hypertension prior to initiating treatment. Without obtaining blood pressure readings outside of the clinic environment, it is impossible to correctly diagnose hypertension, particularly regarding masked hypertension and white coat hypertension.

Stanford Health Care implemented a quality improvement project that provided patients with a home blood pressure device to monitor out of clinic blood pressure readings. The purpose of the project was to improve clinical care …

Nurse Practitioners’ Perceptions Of Telehealth Behaviors, Michelle Austin

Doctoral Projects

Problem: NP’s must be proficient in the behaviors that are required for a successful patient encounter to provide the full benefit of nurse practitioner (NP) telehealth. Consequently, it is imperative for NPs to understand telehealth etiquette behaviors which include the technical and non-technical skills that are necessary for an effective NP-patient patient telehealth encounter (Haney, Kott & Fowler, 2015). Telehealth has been incorporated into healthcare delivery and its use is expanding. In the United States, it is predicted to be used by seven million patients in 2020 (US Department of Health and Human Services, 2018). Appropriate access to health care …

Assessment Of Death Risk Of Breast Cancer Patients With Joint Frailty Models, Ozge Pasin, Ahmet Dirican, Handan Ankarali, Rian Disci, Hasan Karanlik

Saudi Medical Journal

Objectives: To investigate the effects of risk factors on recurrence and death in breast cancer patients, taking into account the dependence between recurrence and death as well as the heterogeneity among individuals. The other aim of this study was to make predictions of death risks with a dynamic model that includes patient’s history and different horizons. Methods: The data of 465 patients who had undergone surgery at the Istanbul University Oncology Institute, Istanbul, Turkey, between 2009 and 2016 were used. For data analysis in this retrospective study, the authors applied the joint frailty model, and the predictions were obtained using …

Remediation Of Crude Petroleum Oil-Water Emulsions Using Microalgae, Mohamed Shafi

Civil and Environmental Theses

Crude petroleum oil spills are among the most important organic contaminations, which result from uncontrolled releases and spillages during transportation or storage. The separated oils on that accumulate on top of the water can be removed by various conventional skimming methods. However, the emulsified portions that remain within the water phase are more difficult to remove and pose significant threats to the environment and could tamper the tertiary treatment in a wastewater treatment plant. Biological treatment, using bacteria, have proven to be an effective method in the removal of the emulsified oils. However, the biomass produced in this case does …

Food Safety Risk In An Indoor Microgreen Cultivation System, Gina Marie Misra

Graduate Theses and Dissertations

Microgreens are immature sprouts of edible plants, sharing some similarities with sprouted seeds and petite leafy greens. Since they are most often grown in containers in buildings or greenhouses, they present a new area for food safety research at the intersection of the built environment and produce farming. Contamination by human pathogens has been extensively studied in other types of produce typically eaten raw, including sprouted seeds, which have been implicated in numerous outbreaks of salmonellosis over the last several decades. There is a paucity of knowledge about the microgreen sector of the fresh-cut industry; thus, it was determined that …

Deprivation Matters: Understanding Associations Between Neighbourhood Deprivation, Unhealthy Food Outlets, Unhealthy Dietary Behaviours And Child Body Size Using Structural Equation Modelling., Victoria Egli, Matthew Hobbs, Jordan A. Carlson, Niamh Donnellan, Lisa Mackay, Daniel Exeter, Karen Villanueva, Caryn Zinn, Melody Smith

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Children residing in neighbourhoods of high deprivation are more likely to have poorer health, including excess body size. While the availability of unhealthy food outlets are increasingly considered important for excess child body size, less is known about how neighbourhood deprivation, unhealthy food outlets and unhealthy dietary behaviours are interlinked.

METHODS: This study involves children aged 8-13 years (n=1029) and resided in Auckland, New Zealand. Unhealthy dietary behaviours (frequency of consumption of unhealthy snacks and drinks) and food purchasing behaviour on the route to and from school were self-reported. Height and waist circumference were measured to calculate waist-to-height ratio …

Plant-Based Diet: How It Affects Health, Sarah Marsland

Senior Honors Projects

This research project aims to investigate the relationship between plant-based dieting and overall health, specifically the prevention and reversal of chronic disease. Two subjects committed to eating a plant-based diet comprised of primarily vegetables, fruits, whole grains and non-processed foods for six weeks. Before beginning, they were asked about their current health status, including a complete health history, and their knowledge of plant-based eating. Throughout the research period, the subjects shared what they were eating, challenges they faced, and any benefits they noticed. Upon completion of the diet, they answered questions about their experience. With this information, the researcher was …

The Realities Of Plant-Based Dieting, Katie Sause

Senior Honors Projects

KATIE SAUSE (Environmental and Natural Resource Economics)

The Realities of Plant-Based Dieting

In modern society, dieting has become a social norm, however, due to improper nutritional education, the transition to limiting diets can lead to adverse health effects. The societal pressures to adhere to extreme beauty standards lead individuals, especially women, to adopt diets based on their incorrect notions about nutrition and health. When this occurs, the dietary goal becomes weight loss rather than health improvements. This paper focuses on two plant-based diets: vegetarianism and whole foods-plant based. To capture the short- term bodily impacts from transitioning to a plant-based …

The Impact Of Stress On Diet, Sleep, And Exercise Amongst College Students, Jessica Rizzo

Senior Honors Projects

Stress is something that everyone faces in their lifetime and has an everlasting impact on their health. College students face high levels of stress throughout the semester, but how is that impacting their behavior? I conducted a survey alongside Dr. Melanson, a professor in the Department of Nutrition and Food Sciences, to see just how college students are reacting to stress. The survey was circulated to different departments and classes to achieve a widespread collection of data. The survey remained completely anonymous and posed questions about eating, exercise, and sleep habits, along with questions on demographics and stress levels. Our …

Introducing Ipe To Uri, Julia Gervais

Senior Honors Projects

The World Health Organization defines Interprofessional education (IPE) as “when two or more students within the health or social science fields learn together during their professional training in order to enable effective collaboration and improve health outcomes”(World Health Organization, 2010). IPE is vital to the health professions because it allows for professionals to adapt a holistic approach that is patient-centered. The core competencies of IPE are: Values and Ethics for Interprofessional Practice; Roles and Responsibilities for Collaborative Practice; Interprofessional Communication Practices; and Interprofessional Teamwork and Team-Based Practice. An online event conducted via WebEx was held for University of Rhode Island …

Safe Sleep: Developmental Implications For Hospitalized Infants, Katherine Kohlsaat

Senior Honors Projects

The rate at which an infant develops both physically and cognitively is significant during sleep, as this is the time when the entire body can dedicate its efforts to this cause. Parents of healthy infants follow the guidelines set by the American Academy of Pediatrics (AAP) relating to safe sleep, and since their introduction in 1992, the rate of Sudden Infant Death Syndrome (SIDS) has decreased by 40% (Center for Disease Control and Prevention, 2016). However, if an infant has been hospitalized since birth due to necessary invasive procedures such as open-heart surgery, these protocols cannot be initially implemented. Common …

Temporal Factors Affecting Foraging Patterns Of A Diurnal Orb-Weaving Spider, Micrathena Gracilis (Araneae: Araneidae), Mitchell Davis Long

Undergraduate Honors Theses

Several studies have investigated the ecological factors that affect behavior in Micrathena gracilis, a diurnal orb-weaving spider that forages on flying insects during the day. However, none yet have considered how the temporal distributions of prey and predator occurrences shape their daily behavioral rhythms, especially web construction, which involves a heavy energetic investment well in advance of potential nutritional benefit. Recently, several orb-weaving spider species have been shown to exhibit a variety of abnormal rhythms, suggesting that circadian clock-controlled rhythms may play an unexpected role in behavioral evolution. Despite the appearance of significant insect abundance in the evenings, M. gracilis …

Microbiome Diversity And Differential Abundances Associated With Bmi, Immune Markers, And Fecal Short Chain Fatty Acids Before And After Synbiotic Supplementation, John Sterrett, W Andrew Clark, Michelle Chandley

Undergraduate Honors Theses

The gut microbiota and its metabolites – namely short chain fatty acids (SCFAs) – interact with the digestive, immune, and nervous systems. Microbiota with disrupted composition are highly associated with obesity, gastrointestinal symptoms, and chronic inflammation. Levels of SCFAs in the feces can represent dynamics of the microbiota, and they represent one mechanism by which the microbiota interacts with its host. This study aimed to further our understanding of associations between microbiota bacterial diversity and SCFAs, immune markers, BMI, and GI symptoms and to identify bacteria that are differentially abundant in different BMI groups and with synbiotic supplementation. Data (SCFAs, …

Effects Of Nicotinamide Riboside And Beta-Hydroxybutyrate On C. Elegans Lifespan, Jeffery Peters

Undergraduate Honors Theses

The nicotinamide riboside (NR) form of vitamin B₃and the ketone body ß-hydroxybutyrate (BHB) are two of the most promising natural compounds yet identified for the treatment of aging and aging-related diseases. Forms of vitamin B₃are precursors for the synthesis of the coenzymes nicotinamide adenine dinucleotide (NAD(H)) and nicotinamide adenine dinucleotide phosphate (NADP(H)). In aged cells levels of NAD⁺decline, decreasing metabolism and decreasing activity of protective sirtuin protein deacetylases. In aged cells NR, but not more common forms of vitamin B3, boost NAD⁺levels. BHB is naturally produced by the body when individuals fast …

Gut Pathophysiology In Mouse Models Of Social Behavior Deficits, Kyla Scott

Undergraduate Honors Theses

Autism spectrum disorders (ASD) encompass neurodevelopment disorders characterized by atypical patterns of development that impact multiple areas of functioning beginning in early childhood. The etiology of ASD is unknown and there are currently no preventative treatment options. Gastrointestinal symptoms are commonly associated comorbidities. The microbiota-gut-brain axis is a multidirectional communication chain that connects the central and enteric nervous system that relates brain function to peripheral intestinal functions. Changes within this axis have been postulated in ASD. For example, the “leaky gut theory” proposes that chronic inflammation is linked to alterations in the bacterial profiles of the gut microbiome and subsequent …

Modeling Frameworks To Evaluate Energy Autarky Of Wastewater Treatment Systems, Gideon Sarpong

Theses and Dissertations

This research demonstrates the use of two novel methodologies to evaluate energy autarky status of wastewater treatment plants (WWTPs) in two steps. Step I (analysis 1 and 2) focuses on overall energy performance evaluation of a conventional activated sludge process (CAS) using a quantitative mass balance model. Step II involves development of a dynamic model that simulates a future wastewater resource recovery facility (WRRF). The step I (analysis 1) focused on small WWTPs with treatment capacities less than 5 MGD. The results revealed that a CAS process can achieve energy autarky or energy-positive status when old technology equipment is replaced …

Quality Of Life Among Colorectal Cancer Patients During Chemotherapy, Chau Minh Than

Master's Theses

This study had the general goal of surveying the quality of life (QoL) and related factors affecting the QoL of colorectal cancer (CRC) patients participating in cancer chemotherapy at University Medical Center (UMC) in Ho Chi Minh City. The study also had the following specific objectives: (a) determining the demographic and clinical characteristics of CRC patients and (b) determining health-related quality of life (HRQoL) and related factors affecting HRQoL of CRC patients receiving cancer chemotherapy. A descriptive cross-sectional design was used. Sixty CRC patients being treated at the UMC participated in this study. The research used the European Organization for …

The Role Of Gibberellic Acid In Aphid-Plant-Arbuscular Mycorrhizal Fungus Interactions, Drew Olson

Master's Theses

Arbuscular mycorrhizal (AM) fungi form beneficial associations with the roots of most terrestrial plants, which is mostly characterized by increased plant nutrient acquisition (phosphate and nitrogen) by the fungi in exchange for carbon and lipids from the plants. These associations can also enhance plant coping mechanisms to abiotic and biotic stresses. However, insect herbivores, such as aphids, can benefit from AM fungi-plant symbioses by altering plant defenses that are driven mainly by the phytohormones jasmonic acid (JA) and salicylic acid (SA). Nevertheless, other phytohormones can modulate plant defenses by altering the balance of the JA and SA signaling pathways, such …

Assessing The Influence Of Riparian Invasion By The Shrub Lonicera Maackii On Terrestrial Subsidies To Headwater Streams, Erin C. Rowekamp, Julia I. Chapman, Ryan Mcewan

Biology Faculty Publications

Invasion of Amur honeysuckle (Lonicera maackii) into riparian areas of headwater streams creates strong potential for alterations of terrestrial subsidies that may drive bottom-up effects on aquatic biota. In this study, we analyzed effects of L. maackii on terrestrial subsidies in stream sites that represented a gradient of invasion intensity in temperate deciduous forests of southwestern Ohio (USA). Leaf litter biomass, terrestrial and aquatic fine woody debris (0.5–9.9 cm diameter) volume and count, and terrestrial and aquatic coarse woody debris (>9.9 cm diameter) volume were analyzed. Based on previous research, we hypothesized that sites with a higher …

A Putative Cystathionine Beta-Synthase Homolog Of Mycolicibacterium Smegmatis Is Involved In De Novo Cysteine Biosynthesis, Saroj Kumar Mahato

Graduate Theses and Dissertations

Mycobacteria include serious pathogens of humans and animals. Mycolicibacterium smegmatis is a non-pathogenic model that is widely used to study core mycobacterial metabolism. This thesis explores mycobacterial pathways of cysteine biosynthesis by generating and study of genetic mutants of M. smegmatis. Published in vitro biochemical studies had revealed three independent routes to cysteine synthesis in mycobacteria involving separate homologs of cysteine synthase, namely CysK1, CysK2, and CysM. However, in vivo data were lacking. The M. smegmatis genome encodes only a CysM homolog and lacks orthologs for CysK1 or CysK2. The gene that codes for CysM is a part of an …

Asymmetric Exchange Rate Pass-Through In Southeast Asian Rice Trade, Taylor Wiseman

Graduate Theses and Dissertations

Asian countries consume approximately 90% of the world’s rice supply. Between 2007 and 2014, Thailand, Vietnam, and India accounted for 60% of the world’s exports of rice. This paper estimates the impact of exchange rate fluctuations on bilateral trade flows in Southeast Asia. Because most Southeast Asian countries have state trading enterprises or agencies controlling rice trade, this analysis will provide insight as to whether these agencies respond to exchange rate fluctuations in a manner consistent with economic theory. Behavior inconsistent with economic theory could provide evidence of stabilizing domestic prices, market power, or export expansion policies. The analysis focuses …

Unjust Food Systems And Applied Mereology, Shane Ray Epting

Arts, Languages and Philosophy Faculty Research & Creative Works

Conventional food systems are highly complex entities with numerous components that span the globe. Having an overabundance of parts creates 'globalized opacity', a condition wherein the sheer number of parts makes it incredibly challenging to see how these parts fit together. In turn, people cannot see how these systems help create and perpetuate social injustices in select instances. With this notion in mind, it should be no surprise that numerous issues require mitigation. Gaining a clear view of the nature of such problems could improve how food-justice researchers understand the complexity involved in the issues that plague food systems, which …

Estrogen Receptor-Α Expressing Neurons In The Ventrolateral Vmh Regulate Glucose Balance, Yanlin He, Pingwen Xu, Chunmei Wang, Yan Xia, Meng Yu, Yongjie Yang, Kaifan Yu, Xing Cai, Na Qu, Kenji Saito, Julia Wang, Ilirjana Hyseni, Matthew Robertson, Badrajee Piyarathna, Min Gao, Sohaib A Khan, Feng Liu, Rui Chen, Cristian Coarfa, Zhongming Zhao, Qingchun Tong, Zheng Sun, Yong Xu

Children’s Nutrition Research Center Staff Publications

Brain glucose-sensing neurons detect glucose fluctuations and prevent severe hypoglycemia, but mechanisms mediating functions of these glucose-sensing neurons are unclear. Here we report that estrogen receptor-α (ERα)-expressing neurons in the ventrolateral subdivision of the ventromedial hypothalamic nucleus (vlVMH) can sense glucose fluctuations, being glucose-inhibited neurons (GI-ERαvlVMH) or glucose-excited neurons (GE-ERαvlVMH). Hypoglycemia activates GI-ERαvlVMH neurons via the anoctamin 4 channel, and inhibits GE-ERαvlVMH neurons through opening the ATP-sensitive potassium channel. Further, we show that GI-ERαvlVMH neurons preferentially project to the medioposterior arcuate nucleus of the hypothalamus (mpARH) and GE-ERαvlVMH neurons preferentially project to the dorsal Raphe nuclei (DRN). Activation of ERαvlVMH …

Hpv Vaccine In Adolescents: How To Increase Uptake, Natasha Richesin

Physician Assistant Scholarly Project Papers

The human papillomavirus (HPV) is a sexually transmitted virus that affects both males and females of all ages. An HPV vaccine was developed to help protect against harmful infections caused by the virus. This literature review focuses on the relationship between the HPV vaccine and its low uptake from untoward events, misinformation surrounding the vaccine, and different education methods. PubMed, Clinical Key, and Cochrane electronic databases are used for the literature review. A comprehensive literature review was conducted, and articles utilized were based on the age of the population being 11 to 29 years old, the HPV vaccine’s involvement in …

The Gut-Brain Axis: Treating Depression Through Microbiome Alterations, Alexandra Bachman-Williams

Physician Assistant Scholarly Project Papers

The purpose of this research and literature review is to explore the possible role that gut microbiome alterations have in the treatment of neurobehavioral diseases; specifically, anxiety and depression. This literature review searched PubMed, CINAHL, and Clinical Key. A variety of key terms were used during the search. Due to the field of research being relatively new and limited, studies from the last ten years and animal models were included in the study. Studies were excluded due to poor design or if the studies did not include anxiety or depression in the research. The research shows that there are the …

The Effects Of Initiating Metformin, To Prevent Or Delay Type 2 Diabetes, In Patients With Prediabetes, Kelsey Abraham

Physician Assistant Scholarly Project Papers

The purpose of this literature review is to explore metformin’s role in the treatment of patients with prediabetes within the primary care setting. The efficacy of metformin versus lifestyle modifications will be compared as well as metformin, as adjunctive therapy, to lifestyle modifications. Along with efficacy, a systematic analysis will examine the three abovementioned therapies regarding diabetes risk reduction. Lastly, this review will examine the safety and tolerability of metformin, specifically in patients with prediabetes. The data presented shows evidence that lifestyle modifications are first-line treatment for prediabetes while metformin use should be reserved for those who fail lifestyle modifications …

Methamphetamine: A Potential Risk Factor For Neurodegenerative Conditions, Katelyn Sarlette

Physician Assistant Scholarly Project Papers

Methamphetamine (METH) is a highly addictive substance that persists to be a major drug of abuse within the United States, particularly the Midwest regions. While some of the major health ramifications are well documented, its neurological impact is not fully understood. Neurodegenerative conditions like multiple sclerosis (MS), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS) continue to increase in frequency, particularly in the Midwest, yet there is no identifiable cause. The purpose of the study was to determine if METH use can contribute to the development of neurological conditions such as MS, PD, and ALS. A literature review was conducted …

Optimal Perioperative Blood Glucose Management And Its Effect On Patient Outcomes, Hilary Narum

Nursing Capstones

No abstract provided.

The Effects Of Elevated Pre-Operative Hemoglobin A1c On Post-Surgical Infection Risk, Emily Koska Rn

Nursing Capstones

No abstract provided.