Digital Commons Network^™

Outpatient Screening Of Health Status Among Postbariatric Patients During The Covid-19 Pandemic In Sao Paulo, Brazil, Karla Fabiana Goessler, Carolina Ferreira Nicoletti, Diego Augusto Nunes Rezende, Sofia Mendes Sieczkowska, Gabriel Perri Esteves, Rafael Genario, Gersiel Nascimento De Oliveira Júnior, Kamila Meireles, Ana Jéssica Pinto, Michele Nakahara-Melo, Roberto De Cleva, Marco Aurélio Santo, John P. Kirwan, Hamilton Roschel, Bruno Gualano

Division of Basic Science Faculty Publications

No abstract provided.

Diet Quality, Weight Loss, And Diabetes Incidence In The Diabetes Prevention Program (Dpp), Benjamin T. Allaire, Ashley H. Tjaden, Elizabeth M. Venditti, John W. Apolzan, Dana Dabelea, Linda M. Delahanty, Sharon L. Edelstein, Mary A. Hoskin, Karla A. Temple, Judith Wylie-Rosett, Lindsay M. Jaacks

Clinical Research Faculty Publications

Background: We evaluated whether diet quality is a predictor of weight loss and reduced diabetes risk, independent of caloric intake in the Diabetes Prevention Program (DPP) cohort, a randomized clinical trial of adults at risk for diabetes. Methods: This secondary analysis included 2914 participants with available data (964 intensive lifestyle (ILS), 977 metformin, 973 placebo). Dietary intake was assessed using a 117-item food frequency questionnaire. Diet quality was quantified using the Alternative Healthy Eating Index 2010 (AHEI). AHEI ranges from 0 to 110, with higher scores corresponding to higher quality diets. ILS participants had greater improvement (p < 0.001) in AHEI over 1-year (4.2 ± 9.0) compared to metformin (1.2 ± 8.5) and placebo (1.4 ± 8.4). We examined the association between AHEI change and weight change from baseline to 1-year using linear regression, and that between 1-year AHEI change and incident diabetes, using hazard models over an average 3 years follow-up. Models were evaluated within treatment group and adjusted for relevant characteristics including caloric intake, physical activity, BMI and AHEI. Models testing incident diabetes were further adjusted for baseline fasting and 2 h glucose. Results: An increase in AHEI score was associated with weight loss in ILS [β per 10-point increase (SE) -1.2 kg (0.3, p < 0.001)], metformin [− 0. 90 kg (0.2, p < 0.001)] and placebo [− 0.55 kg (0.2, p = 0.01)]. However, AHEI change was not associated with incident diabetes in any group before or after adjustment for weight change. Conclusions: Controlling for weight, diet quality was not associated with diabetes incidence but helps achieve weight loss, an important factor in diabetes prevention.

Early Physical Activity Adoption Predicts Longer-Term Physical Activity Among Individuals Inactive At Baseline, Jessica L. Unick, Michael P. Walkup, Michael E. Miller, John W. Apolzan, Peter H. Brubaker, Mace Coday, James O. Hill, John M. Jakicic, Roeland J.W. Middelbeek, Delia West, Rena R. Wing

Clinical Research Faculty Publications

Background: To examine the relationship between early physical activity (PA) adoption (2, 3, and 4 mo) and longer-term PA adherence (1 y) among individuals who were inactive at baseline and received a lifestyle intervention. Methods: Participants (n = 637) received weekly behavioral weight loss sessions, calorie reduction, and PA goals (50.175 min/wk progression). PA was assessed via self-reported measures at baseline, months 2 to 4, and 1 year. Results: PA at months 2 to 4 was significantly correlated with PA at 1 year (rs = .29..35, P < .01). At all early time points, those failing to meet the prescribed PA goal (early nonadopters) engaged in significantly less PA at 1 year than those meeting the early PA goal (initial adopters). For example, using 2-month criteria, initial adopters engaged in 108.3 minutes per week more at 1 year compared with early nonadopters (P < .01) and had 2.8 times the odds (95% confidence interval, 1.9.4.2) of meeting the 1-year PA goal (≥175 min/wk, P < .01). Conclusions: Failure to achieve PA goals at 2, 3, or 4 months results in less overall PA at 1 year. Thus, PA observed as early as month 2 may be a useful indicator for identifying at-risk individuals who may benefit from more intensive PA intervention strategies.

Chronic Intermittent Hypoxia Triggers A Senescence-Like Phenotype In Human White Preadipocytes, Katarzyna Polonis, Christiane Becari, C. Anwar A. Chahal, Yuebo Zhang, Alina M. Allen, Todd A. Kellogg, Virend K. Somers, Prachi Singh

Clinical Research Faculty Publications

Obstructive sleep apnea (OSA) is a common sleep disorder associated with obesity. Emerging evidence suggest that OSA increases the risk of cardiovascular morbidity and mortality partly via accelerating the process of cellular aging. Thus, we sought to examine the effects of intermittent hypoxia (IH), a hallmark of OSA, on senescence in human white preadipocytes. We demonstrate that chronic IH is associated with an increased generation of mitochondrial reactive oxygen species along with increased prevalence of cells with nuclear localization of γH2AX & p16. A higher prevalence of cells positive for senescence-associated β-galactosidase activity was also evident with chronic IH exposure. …

Long-Term Change In Physiological Markers And Cognitive Performance In Type 2 Diabetes: The Look Ahead Study, Owen T. Carmichael, Rebecca H. Neiberg, Gareth R. Dutton, Kathleen M. Hayden, Edward Horton, F. Xavier Pi-Sunyer, Karen C. Johnson, Stephen R. Rapp, Adam P. Spira, Mark A. Espeland

Clinical Research Faculty Publications

Context: The effects of physiological improvements on cognitive function among persons with type 2 diabetes mellitus (T2DM) are not fully understood. Objective: To determine whether improvements in physiological markers (body weight, blood sugar control, and physical activity) during intensive lifestyle intervention (ILI) are associated with enhancements in cognitive function in older adults with T2DM. Design: Multisite randomized controlled trial. Setting: Academic research centers. Patients or Other Participants: Participants were aged 45-76 years, with T2DM. Intervention: The Action for Health in Diabetes (Look AHEAD) study, a randomized, controlled clinical trial of ILI. Main Outcome Measure: Two to 3 cognitive assessments were …

Influence Of Energy Removal Rate On The Quality Of Minced Meat From Undersized Crawfish During Frozen Storage, Franklin Bonilla, Vondel Reyes, Alexander Chouljenko, Bennett Dzandu, Subramaniam Sathivel

Faculty Publications

Abstract: Undersized crawfish have little economic value and are often discarded. Producing crawfish minced meat (CMM) from undersized crawfish and using an appropriate freezing technique may enable an economically viable market. The objective of this research was to evaluate the effect of the energy removal rate using two techniques, cryogenic freezing (CF) and air blast freezing (BF), on CMM’s quality during frozen storage. CMM was separated into two batches; one batch was cryogenically frozen with liquid nitrogen and the other batch was frozen with an air blast freezer. CMM batches were frozen and stored at − 18 °C. They were …

Effects Of Landscape, Soils, And Weather On Yields, Nitrogen Use, And Profitability With Sensor-Based Variable Rate Nitrogen Management In Cotton, James A. Larson, Melissa Stefanini, Xinhua Yin, Christopher N. Boyer, Dayton M. Lambert, Xia Vivian Zhou, Brenda S. Tubaña, Peter Scharf, Jac J. Varco, David J. Dunn, Hubert J. Savoy, Michael J. Buschermohle

Faculty Publications

Farmers may be reluctant to adopt variable rate nitrogen (VRN) management because of uncertain profits. This study assessed field landscape, soil, and weather effects on optical sensing (OS)-based VRN on cotton (Gossypium hirsutum L.) N rates, yields, and net returns (NRs). Field data were collected from 21 locations in Louisiana, Mississippi, Missouri, and Tennessee, USA, between 2011 and 2014. Data included yields, N rates, and NRs for the farmer practice (FP), OS-based VRN, and OS-based VRN supplemented with other information. Production data were augmented with landscape, soils, and weather data, and ANOVA and logistic regressions were used to identify field …

Relation Of Oral Ulcers To Quality Of Life: A Cross-Sectional Study, Enji Ahmed, Ayat Gaml Abdelnasser, Mai Zakaria, Soheir Gafar

Dentistry

Oral ulcers affect many dental patients; impairing their lives physically, psychologically, and socially. Due to the absence of information about oral ulcers in our population, the authors undertook a pilot study to obtain a more complete picture of prevalence of oral ulcers, its probable risk factors and its burden on the quality of life. Materials and methods The authors performed a cross‑sectional study with 605 adult dental patients. All patients filled a questionnaire inquiring about the risk factors. An oral examination was performed to each participant to determine presence or absence of oral ulcers; and the type of the oral …

A Bibliometric Analysis Of The Aga Khan University Research Contribution In Early Child Development, Peter Gatiti, Anil Khamis

Libraries

The research contribution of the Aga Khan University to the Sustainable Development Goals (SDGs) has been explored through a bibliometric analysis. The analysis shows exponential growth of research across the SDGs undertaken by AKU-affiliated researchers. The analysis identified areas of interdisciplinary research, with a significant focus on societal development of interest to AKU, as per its mandate, and reflective of the work of the Aga Khan Development Network (AKDN) of which AKU is an integral part. Building on the bibliometric analysis, this paper focuses on early childhood development and early childhood education with reference to the SDGs. A specific query …

Investigation Of Sulfur Cycling In Marine Sponge Cinachyrella Spp. From A South Florida Reef, Shelby K. Cain

All HCAS Student Capstones, Theses, and Dissertations

Symbionts within marine sponges are actively participating in the biogeochemical cycles. Among them, the role of symbiont microbes in the sulfur cycle remains a mystery. This study measured the abundance of microbes within the genus Cinachyrella before and after exposure to hydrogen sulfide. A four-part study was conducted: a) five-hour drop experiments, b) vertical distribution experiments, c) five-hour uptake experiments, and d) long-term exposure experiments. The five-hour drop experiment utilized a microsensor to measure sulfide levels, which was lowered 1.0 mm every thirty minutes for a total of 5 hours. Three trials were performed, each with one sponge and a …

"Through A Forest Wilderness:” Native American Environmental Management At Yosemite And Contested Conservation Values In America’S National Parks, Rochelle Bloom, Douglas Deur

Anthropology Faculty Publications and Presentations

Chapter 9. The philosophies and views of nature prevalent in the 19th century West shaped the early National Park Service, and continue to influence park policy today. Park-builders incorrectly viewed early parks as untouched “wilderness,” even as Native peoples continued to occupy, revere, and actively manage lands and resources on these lands. This misapprehension fostered the creation and enforcement of park regulations meant to protect wild spaces, resulting in the displacement of both Native peoples and the culturally significant habitats that they had helped sustain for millennia. Among these regulations, federally imposed restrictions on burning and other traditional plant community …

Struggling Student Teachers: Interventions For Support And Success, Sheree Moser

Department of Teaching, Learning, and Teacher Education: Theses and Other Student Research

Teacher shortages in K-12 schools have created unique challenges for teacher preparation programs. University instructors face the task requirements of supporting candidates from a wide variety of backgrounds at the undergraduate and graduate level. While some of these candidates enter higher education programs skilled, eager, and committed, others are less prepared, requiring significant attention to make it through the program. Exams required by state departments of education and minimum grade point averages influence each candidate’s ability to move forward within the program, causing some students to experience additional struggles related to mental health and financial burdens.

The problem of practice …

Practices Of Athletic Trainers Using Weight Charts To Determine Hydration Status And Fluid-Intervention Strategies, Jeremy M. Eith, Clint R. Haggard, Dawn M. Emerson, Susan Yeargin Ph.D., Atc

Faculty Publications

Context

Determining an athlete's hydration status allows hydration-related concerns to be identified before significant medical or performance concerns arise. Weight charts are an accurate measure of hydration status changes, yet their clinical use by athletic trainers (ATs) is unknown.

Objective

To investigate ATs' use of weight charts in athletic settings and describe their subsequent clinical decisions.

Design

Cross-sectional survey.

Setting

High schools and National Collegiate Athletic Association Divisions I, II, III and National Association Intercollegiate Athletics colleges.

Patients or Other Participants

A total of 354 ATs (men = 162, women = 175; 17 respondents did not answer the demographic questions) …

Practices Of Athletic Trainers Using Weight Charts To Determine Hydration Status And Fluid-Intervention Strategies, Jeremy M. Eith, Clint R. Haggard, Dawn M. Emerson, Susan W. Yeargin Ph.D., Atc

Faculty Publications

Context

Determining an athlete's hydration status allows hydration-related concerns to be identified before significant medical or performance concerns arise. Weight charts are an accurate measure of hydration status changes, yet their clinical use by athletic trainers (ATs) is unknown.

Objective

To investigate ATs' use of weight charts in athletic settings and describe their subsequent clinical decisions.

Design

Cross-sectional survey.

Setting

High schools and National Collegiate Athletic Association Divisions I, II, III and National Association Intercollegiate Athletics colleges.

Patients or Other Participants

A total of 354 ATs (men = 162, women = 175; 17 respondents did not answer the demographic questions) …

In A Nutshell: Nutritional And Environmental Factors Impacting Small Mammal Seed Selection In Northeastern Forests, Nicholas Bryan Moore

Master's Theses and Capstones

Rodents often play vital roles in their ecosystems as seed predators and dispersers and can significantly influence the succession and assembly of plant communities. We conducted seed tray experiments to assess the nutritional and environmental factors that influence selection and foraging time of three common rodent granivores: the white-footed mouse (Peromyscus leucopus), the deer mouse (Peromyscus maniculatus), and the southern red-backed vole (Myodes gapperi) for three common seeds: American beech (Fagus grandifolia), red maple (Acer rubrum), and eastern hemlock (Tsuga canadensis). This work was conducted at Bartlett Experimental Forest located within White Mountain National Forest in New Hampshire. Using mixed-effects …

Data Management Report December 2020, Tennessee. Department Of Intellectual And Developmental Disabilities

Compliance & System Data/Reports

This monthly report provides data on various aspects of the department's activities and programs.

Epigenome-Wide Association Of Infant Feeding And Changes In Dna Methylation From Birth To 10 Years, Yamini Mallisetty

Electronic Theses and Dissertations Archive

Epigenetic markers have been suggested as mediators of early-life nutrition to future health. Prior studies focused on breastfeeding effects on DNA methylation (DNAm), ignoring other feeding modes. In this analysis of the Isle of Wight birth cohort, feeding modes were categorized as exclusive breastfeeding (EBF), exclusive formula feeding (EFF), and mixed feeding based on whether the respective feeding mode lasted for at least 3 months. In addition, in the past, infant feeding modes were assessed using one time point DNAm in childhood, not changes of DNAm. In this paper, methylation differences (Delta DNAm) were calculated by subtracting residual methylation values …

A Telemedicine Follow Up Program To Improve Glycemic Outcomes For Patients With Uncontrolled Type 2 Diabetes, Jonathan R. Beatty

Student Projects for Graduate Degrees

Type 2 Diabetes is responsible for a global public health burden and affects an estimated 30 million people in the United States, many of whom have difficulty reaching glycemic targets. Approximately 15 percent of the diabetic patients in the Family Health Clinic have an A1C above 8.0. Telemedicine shows promise in improving glycemic control and enhancing access to care. Current literature supports the use of telemedicine to improve glycemic outcomes. The purpose of this project was to assess the acceptability and effectiveness of a provider implemented intense telephonic follow-up program on glycemic outcomes and self-management of patients with uncontrolled Type …

The Detection And Treatment Of Diabetes Distress, Kylie Jane Viens

Student Projects for Graduate Degrees

The purpose of this project is to develop evidenced-based, best practice guidelines on detecting and treating diabetes distress for health care providers at Southcentral Foundation (SCF). A need was identified at SCF because health care providers do not currently screen for diabetes distress in patients with type 2 diabetes. Key findings include the importance of detecting and treating diabetes distress, critical times to screen for diabetes distress, and evidenced-based treatment options if diabetes distress is detected. It was determined that the Diabetes Distress Scale is a valid and reliable tool for health care providers to assess diabetes distress in the …

Fostering Place-Based Education And Inclusion In The Classroom Through School Grades, Karina Gonzales-Smith

Student Projects for Graduate Degrees

Place-based education expands the space where students learn by connecting to the outdoors, such as garden-based lessons that are dynamic and have a multidisciplinary curriculum. Students are given the opportunity to learn healthy behaviors, environmentally sustainable practices, and life skills. Inclusion is fostered by giving teachers and students agency in the learning experience. The purpose of this study was to view garden education through the lens of place-based education, critical pedagogy, and social justice. To this end, a lesson plan template was created to facilitate future development of garden-based lessons characterized by responsive curriculum and alignment with academic standards. A …

The Link Between Heart Disease In Low Socioeconomic Communities In America, Khristopher Chea

Nursing | Senior Theses

As a future medical professional in the healthcare field, we continue to see patients admitted for cardiovascular issues. Cardiovascular diseases (CVDs) remain the leading cause of mortality among adults living in the U.S. despite advances in treatment throughout the past century. A number of risk factors such as hypertension, obesity, smoking, and physical inactivity contribute to the significant rise of cardiovascular disease. Research data suggests that there is correlation between cardiovascular disease, low socioeconomic status, and diet. According to the American Phycological Association socioeconomic status is measured by income, educational status, and occupation, and has been shown to be closely …

The Effects Of Moderate-Severe Plaque Psoriasis On Patient Well-Being And Prevention Of Flares, Glenn Devera

Nursing | Senior Theses

Psoriasis is a chronic skin condition that is indicated by red, patchy and scaly skin that can be painful when irritated. Patients with psoriasis have an increased risk for a number of chronic diseases. Despite the expansion of treatments for moderate-to-severe psoriasis over the last decade, patients may still find that treatment strategies are not as successful, leaving them dissatisfied with their treatments. A relationship built upon trust between the nurse and the patient diagnosed with psoriasis may serve to help ensure optimal care. A comprehensive literature review was performed and found that best practices for patient management need to …

Prenatal Care For Undocumented Women In The United States, Cristina Mendoza

Nursing | Senior Theses

Background: While prenatal care is an essential preventive service, access is not equal. Undocumented immigrants in the United States face many barriers that prevent them from accessing primary health care needs, including adequate prenatal care. Throughout the United States, standard Medicaid provides coverage for all pregnancy-related care, encompassing the antenatal period, childbirth, and postpartum. However, undocumented women do not qualify to receive these services. Many studies showed that lack of prenatal care for undocumented pregnant women jeopardizes their health and their neonates’ health by increasing their risk of complications related to pregnancy and birth. Objective: To bring awareness of the …

Gut Microbiota And The Development Of Type 2 Diabetes, Janet Ryan

Nursing | Senior Theses

This paper explores the question: Can interventions focusing on healing the gut microbiome of a prediabetic patient prevent or delay the onset of type 2 diabetes? Diabetes is a major health problem that is becoming the biggest epidemic of the 21^st century. Efforts to derail the progression of disrupted blood glucose metabolism are often futile leaving patients frustrated with a lifelong burden of disease management. Recent studies suggest that collectively the gut microbiome acts as an endocrine organ and that injury to this “organ” can lead to dysfunctional glucose regulation. A comprehensive literature review revealed that further studies are …

The Drug Overdose Epidemic Seen Through Different Lenses, Barbara Blake Gonzalez, Richard Cebula, James V. Koch

Economics Faculty Publications

The age-adjusted death rate from drug overdoses in the United States per 100,000 individuals rose from 6.8 in 2010 to 17.1 in 2018. The most common explanation offered is the deaths of despair hypothesis. We identify additional factors that have contributed to the rise in drug overdose deaths in cities and counties. Methods: We utilize a period fixed effects model with a multi-variate panel data set for 94 independent cities and counties in Virginia for the period 2008 through 2017. Results: The drug overdose mortality rate is: (a) an increasing function (prob.

Development Of A Young Parents' Guide For Income, Education, Employment, And Health Resources In Southcentral Alaska, Hannah Warren

Student Projects for Graduate Degrees

The issue of pregnancy at a younger age is a global problem that affects the socioeconomic status of people living in our community. The goal of this project was to compile a working, comprehensive, accurate and easy to read resource guide. The primary users of the guide are to be youth who may be planning to be pregnant, pregnant, engaging in risky sexual behaviors which may or may not lead to pregnancy, and/or parenting. Other intended users of the guide are to be workers in the social services and public health field. The resource guide created was assessed by the …

Harvester Ants Reduce Seed Survivorship In Slickspot Peppergrass, A Rare Mustard Endemic To Idaho, Jennifer A. Brown, Ian C. Robertson

Biology Faculty Publications and Presentations

Seed predation can significantly reduce the reproductive success of individual plants and their populations. The consequences of seed predation often are most pronounced for rare plant species, in which loss of seeds can have a disproportionate effect on populations. The present study examined the effects of seed predation by Owyhee harvester ants (Pogonomyrmex salinus) on seed survivorship in slickspot peppergrass (Lepidium papilliferum), a rare mustard endemic to sagebrush-steppe habitat in southwestern Idaho. Within sagebrush-steppe, L. papilliferum is restricted to microsites known as “slick spots”—shallow depressions of soil characterized by distinct clay layers and surface water retention …

Muscadine Or Amla Extracts Standardized To Ellagic Acid Content Ameliorate Glucolipotoxicity Associated Β-Cell Dysfunction Via Inhibition Of Il-1Β And Improved Insulin Secretion, Srikanth Earpina, Karen Mcdonough, Millicent Yeboah-Awudzi, Kristina J. Cook, Sita Aggarwal, Jack N. Losso

Faculty Publications

Glucolipotocixity induces IL-1 β secretion which impairs pancreatic β-cell insulin secretion. Ellagic acid and urolithin A have strong anti-inflammatory effect on cells. Muscadine and amla are very good sources of ellagic acid. The present study examined the effect of ellagic acid, ellagic acid-rich muscadine or amla extract, or urolothin A on inflammation in β cells under glucolipotoxic conditions. Rat NIT-1 β cells were incubated in glucolipotoxic conditions (33.3 mM glucose, 250 μM palmitic acid or 33.3 mM glucose + 250 μM palmitic acid with or without ellagic acid, ellagic acid-rich muscadine or amla extracts standardized to its ellagic acid content, …

Evaluating The Implementation Of The Switch® School Wellness Intervention And Capacity-Building Process Through Multiple Methods, Gabriella M. Mcloughlin, Priscila Candal, Spyridoula Vazou, Joey A. Lee, David A. Dzewaltowski, Richard R. Rosenkranz, Lorraine Lanningham-Foster, Douglas A. Gentile, Laura Liechty, Senlin Chen, Gregory J. Welk

Faculty Publications

Background: School wellness programming is important for promoting healthy lifestyles and academic achievement in youth; however, research is needed on methods that can help schools implement and sustain such programs on their own. The purpose of this study was to investigate factors within and outside the school environment that influenced school capacity for implementation and potential sustainability of wellness programming. Methods: As part of the School Wellness Integration Targeting Child Health (SWITCH®) intervention, elementary school wellness teams (N = 30) were guided through a capacity-building process focused on promoting the adoption of healthy lifestyle behaviors in students. Data on implementation …

Implications Of Lysine Acetylation On The Enzymes Of The Tca Cycle, Sumana Venkat

Graduate Theses and Dissertations

The tricarboxylic acid (TCA) cycle is a central route for the energy production via oxidative phosphorylation and is ubiquitous throughout nature. Apart from playing a major role in energy provision, it is also essential for a wide range of physiological functions in any organism. Although an increasing emphasis is laid on the interlinking role of the cycle, its regulation and control are less very less understood. As the field progresses, the consequences of TCA cycle anomalies are shown to be tied to various cancers and other disorders. The matter becomes more complex when considering the varying functions of the isozymes …