Digital Commons Network^™

Long-Stay Patients In Pediatric Intensive Care Units: Five-Years, 2-Points, Cross-Sectional Study, Mohamad-Hani A. Temsah, Ayman A. Al-Eyadhy, Fahad M. Al-Sohime, Marwah M. Hassounah, Mohammed A. Almazyad, Gamal M. Hasan, Amr A. Jamal, Ali A. Alhaboob, Majed A. Alabdulhafid, Noura A. Abouammoh, Khalid A. Alhasan, Abdullah A. Alwohaibi, Abdullah T. Alturki

Saudi Medical Journal

Objectives: To explore the changing patterns of long-stay patients (LSP) to improve the utilization of pediatric intensive care units (PICUs) resources. Methods: This is a 2-points cross-sectional study (5 years apart; 2014-2019) conducted among PICUs and SCICUs in Riyadh, Saudi Arabia. Children who have stayed in PICU for more than 21 days were included. Results: Out of the 11 units approached, 10 (90%) agreed to participate. The prevalence of LSP in all these hospitals decreased from 32% (48/150) in 2014 to 23.4% (35/149) in 2019. The length of stay ranged from 22 days to 13.5 years. The majority of LSP …

Impact Of Covid-19 On People's Liv Elihoods, Their Health And Our Food Systems

Saudi Medical Journal

No abstract provided.

Molecular And Physiological Assessment Of Salinity Stress Tolerance In Transgenic Arabidopsis Lines Expressing A Solanum Tuberosum Ribosome-Binding Protein, Onoud Rashed Saeed Ali Alyammahi

Biology Theses

Ribosomal proteins are highly conserved components of basal cellular organelles, primarily associated with translation of mRNA leading to protein synthesis. Additionally, some of these proteins are known to play critical role in plants RNA metabolism during stress responses, growth, and development. In this study, transgenic Arabidopsis plants expressing a ribosomal protein S27 (hereafter D26) isolated from Solanum tuberosum was subjected to NaCl-induced salinity stress conditions, to evaluate their putative stress resistance. Transgenic plants were exposed to high salinity stress, induced by 200 mM NaCl and physiological and biochemical assays were performed. The D26 transgenic plants demonstrated improved plant height and …

Implementation Of Surgical Site Infection Surveillance In Low- And Middle-Income Countries: A Position Statement For The International Society For Infectious Diseases, Shaheen Mehtar, Anthony Wanyoro, Folasade Ogunsola, Emmanuel A. Ameh, Peter Nthumba, Claire Kilpatrick, Gunturu Revathi, Anastasia Antoniadou, Helen Giamarelou, Anucha Apisarnthanarak

Pathology, East Africa

Surgical site infection (SSI) rates in low- and middle-income countries (LMICs) range from 8 to 30% of procedures, making them the most frequent healthcare-acquired infection (HAI) with substantial morbidity, mortality, and economic impacts. Presented here is an approach to surgical site infection prevention based on surveillance and focused on five critical areas identified by international experts. These five areas include 1. Collecting valid, high-quality data; 2. Linking HAIs to economic incapacity, underscoring the need to prioritize infection prevention activities; 3. Implementing SSI surveillance within infection prevention and control (IPC) programs to enact structural changes, develop procedural skills, and alter healthcare …

Borderplex Business Barometer, Volume 4, Number 11, Thomas M. Fullerton Jr., Steven L. Fullerton, Ana Gutierrez Zubiate, Ignacio Santana

Border Region Modeling Project

No abstract provided.

The Association Between Physiological Sources Of Pain And Sleep Quality In Older Adults With And Without Dementia, Crystal-Rae Waltons, Christine R. Kovach

College of Nursing Faculty Research and Publications

The association of musculoskeletal pain, respiratory distress, gastrointestinal discomfort, and genitourinary pain to sleep quality in 89 persons with and without dementia was examined in the current exploratory, cross-sectional, observational quantitative design. Sources of pain were recorded, with 37.1% of the sample reporting urinary retention, 30.3% reporting genitourinary discomfort, and 53.9% reporting gastrointestinal discomfort. Mild scores of musculoskeletal pain and respiratory discomfort were elicited in >75% of the sample. An actigraph was used to measure sleep variables. Findings from this research illustrated dementia, gender, pillow use, respiratory distress, and urinary retention were statistically significantly associated with nighttime sleep quality. Results …

Unique And Cumulative Effects Of Intimate Partner Cybervictimization Types On Alcohol Use In Lesbian, Gay, And Bisexual Emerging Adults, Oscar Trujillo, Jorge I. Cantu, Ruby Charak

Psychological Science Faculty Publications

The use of modern technology has inadvertently created newer platforms for intimate partner victimization to take place. The present study investigated (i) whether psychological, sexual, and stalking intimate partner cybervictimization (cyber IPV) types were uniquely associated with alcohol use, and (ii) whether there were additive effect of cyber IPV types on alcohol use, after controlling for histories of childhood maltreatment types, face-to-face intimate partner victimization among lesbian, gay, and bisexual (LGB) emerging adults. Participants were 277 self-identifying LGB individuals in the age range of 18-29 years (M = 25.39, SD = 2.77; 16.6% lesbian, 25.6% gay, 43% bisexual women). Participants …

Fatal Covid-19 Infection In A Patient With Long-Chain 3-Hydroxyacyl-Coa Dehydrogenase Deficiency: A Case Report, Parith Wongkittichote, James R Watson, Jennifer M Leonard, Elizabeth R Toolan, Patricia I Dickson, Dorothy K Grange

2020-Current year OA Pubs

Long-chain fatty-acyl CoA dehydrogenase deficiency (LCHADD) is an inborn error of long chain fatty acid oxidation with various features including hypoketotic hypoglycemia, recurrent rhabdomyolysis, pigmentary retinopathy, peripheral neuropathy, cardiomyopathy, and arrhythmias. Various stresses trigger metabolic decompensation. Coronavirus disease 2019 (COVID-19) is a pandemic caused by the RNA virus SARS-CoV-2 with diverse presentations ranging from respiratory symptoms to myocarditis. We report a case of a patient with LCHADD who initially presented with typical metabolic decompensation symptoms including nausea, vomiting, and rhabdomyolysis in addition to mild cough, and was found to have COVID-19. She developed acute respiratory failure and refractory hypotension from …

Modeling Age-Dependent Developmental Changes In The Expression Of Genes Involved In Citrulline Synthesis Using Pig Enteroids, Mahmoud A Mohammad, Inka C Didelija, Barbara Stoll, Douglas G Burrin, Juan C Marini

Children’s Nutrition Research Center Staff Publications

metabolism of citrulline and arginine are well characterized. Enteroids, a novel ex-vivo model that recreates the three-dimensional structure of the intestinal crypt-villus unit, have shown to replicate molecular and physiological profiles of the intestinal segment from where they originated ("location memory").

Objective: The present study tested the hypothesis that enteroids recapitulate the developmental changes observed in vivo regarding citrulline production in pigs ("developmental memory").

Methods: Preterm (10- and 5-d preterm) and term pigs at birth, together with 7- and 35-d-old pigs were studied. Gene expression was measured in jejunal samples and in enteroids derived from this segment. Whole body citrulline …

Type 1 Doing Well: Pilot Feasibility And Acceptability Study Of A Strengths-Based Mhealth App For Parents Of Adolescents With Type 1 Diabetes, Marisa E Hilliard, Viena T Cao, Sahar S Eshtehardi, Charles G Minard, Rana Saber, Debbe Thompson, Lefkothea P Karaviti, Barbara J Anderson

Children’s Nutrition Research Center Staff Publications

Background: We evaluated the feasibility and acceptability of a pilot behavioral intervention delivered to parents of adolescents with type 1 diabetes (T1D) via mobile-friendly web app. The Type 1 Doing Well app aimed to promote supportive family diabetes management by helping parents recognize and reinforce teens' positive diabetes-related behaviors ("strengths").

Methods: Parents (n = 80, 74% recruitment) of adolescents (age range = 12-17 years, M = 15.3 ± 1.5 years, 59% female, 56% insulin pump, M hemoglobin A1c (HbA1c) = 9.0% ± 2.1%) were randomized 2:1 to intervention or control (i.e., usual medical care with or without app) for …

Β-Cell Impairment And Clinically Meaningful Alterations In Glycemia In Obese Youth Across The Glucose Tolerance Spectrum, Joon Young Kim, Hala Tfayli, Fida Bacha, Sojung Lee, Nour Gebara, Silva Arslanian

Children’s Nutrition Research Center Staff Publications

Background/aims: In obese youth, it is not clear what degree of β-cell impairment translates to glucose dysregulation commensurate with shifts from normal glucose tolerance (NGT) to impaired glucose tolerance (IGT) to type 2 diabetes. We aimed to investigate the quantitative relationship between β-cell (clamp-measured disposition index [DI]) and OGTT glucose area under the curve (G-AUC) in obese youth across the spectrum of glucose tolerance.

Methods: Data from 152 youth (58 African-American [AA] and 94 American-White [AW]; 73 NGT, 48 IGT, and 31 type 2 diabetes) who completed a 3-h hyperinsulinemic (80 mu/m2/min)-euglycemic clamp, and a 2-h hyperglycemic (225 mg/dL) clamp …

N Y State Dent J November 2020

The New York State Dental Journal

The New York State Dental Journal (NYSDJ) is produced by the New York State Dental Association (NYSDA) six times a year, in January, March, April, July, September and November. Each issue features clinical and scientific articles written by researchers and practitioners from around the globe and is subject to review by a panel of specialists convened by the Editor.

Issues include cover and feature articles alongside regular columns with regional news impacting the New York membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Development And Validation Of A Food Frequency Questionnaire For The Adult Emirati Population For Use In Epidemiological Studies, Najoua El Mesmoudi

Dissertations

No abstract provided.

A New Beginning: Early Refugee Integration In The United States, Van C. Tran, Francisco Lara-García

Publications and Research

The U.S. refugee population not only has grown dramatically, but the countries from which the refugees are fleeing have also diversified over the last decade. Focusing on five recent refugee groups—Bhutanese, Burmese, Iraqis, Somalis, and Cubans, we examine how premigration characteristics and postmigration integration policies shape early socioeconomic integration in the United States. Our analyses point to three findings. First, early socioeconomic outcomes show only modest differences across refugee groups, despite significant variation in premigration selectivity in human capital. Second, the two possible pathways toward integration are schooling and employment. Third, postmigration integration policies matter. Our findings highlight the role …

Medical Disputes And Conflicting Values: Is There A “Right To Die” Later?, Janet L. Dolgin

BYU Law Review

No abstract provided.

Childhood Medulloblastoma, Naureen Mushtaq, Shahzadi Resham, Muhammad Shahzad Shamim, Bilal Mazhar Qureshi, Quratulain Riaz, Eric Bouffet

Section of Haematology/Oncology

Medulloblastoma is the most common malignant brain tumour in children and is a major cause of mortality and morbidity, particularly in low- and middle-income countries. It has been risk-stratified on the basis of clinical (age, metastasis and extent of resection) and histological subtypes (classic, desmoplastic and anaplastic). However, recently medulloblastoma has been sub-grouped by using a variety of different genomic approaches, such as gene expression profiling, micro-ribonucleic acid profiling and methylation array into 4 groups, namely Wingless, Sonic hedgehog, Group 3 and Group 4. This new sub-grouping has important therapeutic and prognostic implications. After acute leukaemia, brain tumour is the …

Animal Science E-Newsletter, November 2020, University Of Arkansas, Fayetteville. Department Of Animal Sciences

Animal Science e-Newsletter

No abstract provided.

Implementation Of The Mtss Process In Kearney Public Schools, Chelsea Feusner

Department of Educational Administration: Dissertations, Theses, and Student Research

To support multiple needs, districts have worked to enrich or remediate students through differentiated objectives, programs, and initiatives. The goal of a Multi-Tiered System of Supports framework is to create a system that supports all students and provides robust interventions and programs at all levels, in multiple areas of education. This cross-sectional study will investigate MTSS implementation through a self-assessment survey of school principals and teachers in Kearney Public Schools (KPS). The information collected and analyzed to support the administrative team’s planning, implementation, and measurement of effectiveness. The research will also be able to support the continued implementation of MTSS …

Growth Of Microalgae For Simultaneous Treatment Of Industrial Wastewater And Biodiesel Production, Mohammed Ahmad Tawfiq Abujayyab

Chemical and Petroleum Engineering Theses

The treatment of industrial wastewater contaminated with phenols is among the main challenges in the chemical, and particularly the petrochemical industry. Phenols, which present in considerable amounts in industrial wastewater, are toxic even at low concentrations. Therefore, it is essential to reduce their concentrations in water to harmless levels before being discharged. On the other hand, the dependence on the conventional fossil sources of energy, which is non-renewable, is not sustainable and can cause harmful environmental impacts. Therefore, in this work, the dual utilization of microalgae as a cheap and efficient means to remove phenolic compounds commonly found in refinery …

Investigating Early Childhood Educators’ Experiences In Teaching Phonological Awareness: A Case Study, Kristine Reilly

All Theses And Dissertations

Literacy instruction, or teaching educators how to teach reading, is increasingly important as the effects of illiteracy impact everyone from the individual level to the societal level. The cost of illiteracy to the global economy is estimated at $1.2 trillion U.S. dollars (World Literacy Foundation, 2015). Improving literacy for all becomes a social justice concern as access to literacy opens avenues to further education and to improved physical and mental wellbeing. Over the past forty years, neurocognitive and behavioral science has demonstrated how the human brain learns to read. However, educator training programs and professional development have not kept pace …

Data Management Report November 2020, Tennessee. Department Of Intellectual And Developmental Disabilities

Compliance & System Data/Reports

This monthly report provides data on various aspects of the department's activities and programs.

Fintech: New Battle Lines In The Patent Wars?, Megan M. La Belle, Heidi Mandanis Schooner

Cardozo Law Review

Historically, financial institutions have relied on trade secrets and first-mover advantages, rather than patents, to protect their inventions. For the few financial patents that were issued, conventional wisdom was that they weren’t terribly interesting or important. In our 2014 study on financial patents, we showed that banks were breaking from past patterns and increasingly seeking patent protection. We explained that financial institutions were primarily building their patent portfolios as a defensive measure—i.e., to protect themselves from infringement suits. Indeed, the finance industry successfully lobbied Congress to include provisions in the America Invents Act of 2011 that made it easier to …

Chemical Effects Of Cold Atmospheric Plasma On Food Nutrients, Juan Manuel Pérez Andrés

Doctoral

A range of nonthermal techniques have demonstrated process efficacy in ensuring food product safety, extension of shelf-life and in general a retention of key quality attributes. However, various physical, chemical and biochemical effects of nonthermal techniques on both macro and micronutrients are evident, leading to both desirable and undesirable changes in food products. It is important to outline the effects of non-thermal techniques on food chemistry and the associated degradation mechanisms with the treatment of foods. Oxidation is one of the key mechanisms responsible for undesirable effects induced by non-thermal techniques. Degradation of key macromolecules largely depends on the processing …

The Future Of Policy Tools: Promises And Pitfalls, Michael Howlett, Ishani Mukherjee, Sarah Giest

Research Collection School of Social Sciences

The study of policy tools has been undertaken for several decades. It has isolated and examined many different types of tools utilized by governments over the course of history and examined in detail how they are arranged into policy mixes or portfolios of tools. Recent developments in society and technology, however, have brought to the fore the possibility of using new or previously little-used tools such as platforms, co-production, nudges, as well as data-driven techniques, such as big data and artificial intelligence. These are added to the toolbox governments have at their disposal when designing policy responses to both new …

Women Who Endured Childhood Maltreatment: How Resiliency Led To Lower Mental Health Issues, Rebecca Lee Hirshman

Doctoral Dissertations and Projects

The purpose of this study was to have a better understanding of the positive impact that resiliency has on an individual that has endured childhood maltreatment. This qualitative study focused on the information gathered from seven women ranging in age from 18 to 60 years old. Each participant answered three questionnaires (the Adverse Childhood Experience, Brief Resilience Coping Scale, and a Survey Questionnaire) prior to participating in a Zoom interview. This study elaborated on the four types of childhood maltreatment, what prompted the need for programs and interventions, the detrimental effects it has on the development of children and their …

Green Synthesis, Characterization, Antioxidant And Anticancer Activities Of Silver Nanoparticle Using Moringa Peregrina Leaf Extract, Khaled Saeed Al Baloushi

Theses

The sustainable green synthesis process for the development of environment-friendly, toxicant-free and biocompatible nanoparticles establishes important aspects in nanotechnology research. Even though; nanoparticles can be produced by either conventional physical and chemical or green synthesis, synthesizing nanoparticles using plant extracts as reducing and capping agents is acceptable. The benefits of plant extract mediated synthesis of silver nanoparticles comprise economic viability, quick synthesis, toxicity free, cost-effectiveness and large scale synthesis. In that way, the aqueous extract of Moringa peregrina leaves was used to synthesizes silver nanoparticles. The silver nanoparticles were characterized by various spectral studies including FT-IR, SEM, HR-TEM and XRD. …

Chronic Ulcers And Malnutrition In An African Patient\, Timothy G Singer, Monica A Bray, Audrey Chan, Saki Ikeda, Brittany Walters, Maren Y Fuller, Carla Falco

Faculty, Staff and Students Publications

An 11-year-old female with a congenitally malformed left hand, sickle-cell trait, asthma, and history of appendicitis was transferred from Zambia for evaluation and treatment of widespread suppurative and ulcerative skin lesions that typically appeared following trauma to her skin. The ulcers first presented 3 years earlier but had markedly worsened in the 9 months prior to transfer, spreading circumferentially on her extremities and abdomen at the site of an appendectomy. They were painful and did not resolve with multiple courses of intravenous (IV) antibiotics and close management by a Pediatric Infectious Disease specialist working for a non-governmental organization (NGO) in …

Fostering Community Supported Agriculture In Utah, Kelsey Hall, Roslynn Brain

All Current Publications

This curriculum contains seven modules that describe the fundamentals of CSA, CSA marketing and outreach, CSA management, CSA pricing, CSA crop planning, legal concerns for CSA operations, and additional resources.

Cross-Cultural Adaptation Of Children´S Environmental Health Questionnaires For Nursing Students In England, Cristina Álvarez-García, Carmen Álvarez-Nieto, Rachel Carter, Janet Kelsey, Sebastián Sanz-Martos, I López-Medinaa

School of Nursing and Midwifery

Objectives: Children are among the most vulnerable population groups with regard to environmental risks. Nursing students must be fully educated on children’s environmental health as they are in a key position to prevent and reduce the effects of environmental hazards. The main objective of this study was to adapt and validate an English language version of two questionnaires about children’s health and the environment, to assess the knowledge and skills of student nurses in England. Design: Observational cross-sectional study. Setting: A university in Southern England. Method: The study involves translating, adapting and validating the Children’s Environmental Health Knowledge Questionnaire (ChEHK-Q) …

Diroximel Fumarate (Drf) In Patients With Relapsing-Remitting Multiple Sclerosis: Interim Safety And Efficacy Results From The Phase 3 Evolve-Ms-1 Study, Robert T Naismith, Et Al

2020-Current year OA Pubs

BACKGROUND: Diroximel fumarate (DRF) is a novel oral fumarate for patients with relapsing-remitting multiple sclerosis (RRMS). DRF and the approved drug dimethyl fumarate yield bioequivalent exposure to the active metabolite monomethyl fumarate; thus, efficacy/safety profiles are expected to be similar. However, DRF's distinct chemical structure may result in a differentiated gastrointestinal (GI) tolerability profile.

OBJECTIVE: To report interim safety/efficacy findings from patients in the ongoing EVOLVE-MS-1 study.

METHODS: EVOLVE-MS-1 is an ongoing, open-label, 96-week, phase 3 study assessing DRF safety, tolerability, and efficacy in RRMS patients. Primary endpoint is safety and tolerability; efficacy endpoints are exploratory.

RESULTS: As of March …