Digital Commons Network^™

Impact Of Diabetes On The Gut And Salivary Iga Microbiomes, Eric L Brown, Heather T Essigmann, Kristi L Hoffman, Noah W Palm, Sarah M Gunter, Joel M Sederstrom, Joseph F Petrosino, Goo Jun, David Aguilar, William B Perkison, Craig L Hanis, Herbert L Dupont

Faculty, Staff and Student Publications

Mucosal surfaces like those present in the lung, gut, and mouth interface with distinct external environments. These mucosal gateways are not only portals of entry for potential pathogens but also homes to microbial communities that impact host health. Secretory immunoglobulin A (SIgA) is the single most abundant acquired immune component secreted onto mucosal surfaces and, via the process of immune exclusion, shapes the architecture of these microbiomes. Not all microorganisms at mucosal surfaces are targeted by SIgA; therefore, a better understanding of the SIgA-coated fraction may identify the microbial constituents that stimulate host immune responses in the context of health …

November 15, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

We are currently evaluating the full extent and impact on our campus community of the announcement by the Michigan Governor on Sunday evening. This announcement includes limitations to be imposed statewide effective this Wednesday.

Actions to be taken by the University to be in compliance with local and state directives will be determined and communicated promptly to the campus community.

Increasing The Stability And Applications Of Highly Active Naturally Occurring Antimicrobial Peptides, Wayne Travers

Doctoral

Antimicrobial Resistance is a fundamental threat to global health and safety” (WHO, 2016). Nisin, a 34 amino acid lanthipeptide, is currently used as a food preservative worldwide and has been used for decades without significant bacterial resistance having developed. It is an extremely active molecule which kills a range of different bacterial species. However nisin, along with some other similar peptides, suffers from low stability and solubility at physiological pH, which severely restricts its possible use in human and veterinary medicine. This research is concerned with increasing the stability of nisin in physiological pH systems; the stability of the dehydroalanine …

Trust: Assessing The Efficacy Of An Intervention To Increase Hiv Self‑Testing Among Young Black Men Who Have Sex With Men (Msm) And Transwomen, Victoria Frye, Vijay Nandi, Mark Q. Paige, Jermaine Mccrossin, Debbie Lucy, Marya Gwadz, Patrick S. Sullivan, Donald R. Hoover, Leo Wilton

Publications and Research

HIV testing among young Black MSM and transwomen (YBMSM/TW) is the gateway to biomedical HIV prevention or treatment. HIV self-testing (HST) is a method that may increase consistent HIV testing. TRUST, a brief, peer-based behavioral intervention, was designed to increase uptake of consistent (every three months) HST among YBMSM/TW in New York City. To test the efficacy of the intervention, we randomized 200 friend pairs into either the intervention condition (TRUST) or a time and attention control condition. A modified intent-to-treat analysis found that self-reported HST at 3-month follow-up was statistically significantly higher (uOR 2.29; 95% CI 1.15, 4.58) and …

2020-11-15_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

A Bayesian Network Analysis Of The Human Exposure To Escherichia Coli Bacteria In The Environment, Brandon G. De Flon

Mathematics & Statistics ETDs

Diarrhea is a leading cause of death worldwide because a lack thereof in household sanitization exposes humans to high concentrations of pathogenic Escherichia coli. In 2016, the University of New Mexico’s Nepal Study Center collected cross-sectional survey data using proportional random sampling on three communities in Western Nepal. Structural and parameter learning estimation and approximate inference of Bayesian networks studied diarrheagenic E. coli exposure while incorporating participation in sanitary behaviors, access to sanitary built-in environments, and other human characteristics. Of the reported sickness, hand washing resulted in a 20 percent decrease, water treatment 8 percent, and both 28 percent. Of …

2020-11-14_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

“A Welcome, A Warning And A Wish: On Entering Lmu Through The ‘First To Go Program’ In The Year 2020”, Dean Bryant Keith Alexander, Phd

First-Gen Voices: Creative and Critical Narratives on the First-Generation College Experience

"As many as you know, Loyola Marymount University (LMU) has a powerful mission statement that includes three pillars that are often cited and recited: The encouragement of learning; the education of the whole person; and the service of faith and the promotion of justice.

As I welcome you to campus, I welcome you into the recognition of this now shared mission statement as a joint commitment to encouraging an integration of knowledge; in which “faith and reason bear witness to the unity of all truth” (Ex Corde Ecclesiae, 1990, #17) and to instill in our students the abilities for life-long …

2020-11-13_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

2020 Sigma International Nurse Researcher Hall Of Fame: Conversation With The Honorees, Session 2, Jason E. Farley, Vanora Hundley, Susan M. Latter, Karen A. Monsen

International Nursing Research Congress (INRC)

Attendees will experience the opportunity to hear International Nurse Researcher Hall of Fame honorees discuss their work and their research journeys. Session moderated by 2019-2021 President, Richard Ricciardi, PhD, CRNP, FAANP, FAAN.

Antibody Fc Glycosylation Discriminates Between Latent And Active Tuberculosis, Lenette L. Lu, Jishnu Das, Patricia S. Grace, Sarah M. Fortune, Blanca I. Restrepo, Galit Alter

School of Medicine Publications

Background. Mycobacterium tuberculosis remains a global health problem and clinical management is complicated by difficulty in discriminating between latent infection and active disease. While M. tuberculosis-reactive antibody levels are heterogeneous, studies suggest that levels of IgG glycosylation differ between disease states. Here we extend this observation across antibody domains and M. tuberculosis specificities to define changes with the greatest resolving power.

Methods. Capillary electrophoretic glycan analysis was performed on bulk non-antigen–specific IgG, bulk Fc domain, bulk Fab domain, and purified protein derivative (PPD)- and Ag85A-specific IgG from subjects with latent (n = 10) and active (n = 20) tuberculosis. PPD-specific …

A Praziquantel Treatment Study Of Immune And Transcriptome Profiles In Schistosoma Haematobium-Infected Gabonese Schoolchildren, Lucja A Labuda, Ayola A Adegnika, Bruce A Rosa, John Martin, Ulysse Ateba-Ngoa, Abena Serwaa Amoah, Honorine Mbenkep Lima, Lynn Meurs, Moustapha Mbow, Mikhael D Manurung, Jeannot F Zinsou, Hermelijn H Smits, Peter G Kremsner, Makedonka Mitreva, Maria Yazdanbakhsh

2020-Current year OA Pubs

BACKGROUND: Although Schistosoma haematobium infection has been reported to be associated with alterations in immune function, in particular immune hyporesponsiveness, there have been only few studies that have used the approach of removing infection by drug treatment to establish this and to understand the underlying molecular mechanisms.

METHODS: Schistosoma haematobium-infected schoolchildren were studied before and after praziquantel treatment and compared with uninfected controls. Cellular responses were characterized by cytokine production and flow cytometry, and in a subset of children RNA sequencing (RNA-Seq) transcriptome profiling was performed.

RESULTS: Removal of S haematobium infection resulted in increased schistosome-specific cytokine responses that were …

Vaccine Delivery To Remote Regions Of The World Using A Novel Delivery Platform, Amelia Bierle

Shared Knowledge Conference

Vaccination has been the most impactful medical intervention ever devised to prevent the global spread of infectious disease. In the past 200 years, vaccination has been credited to have saved more lives from a human intervention only after clean water and improved sanitary conditions. Society has seen this through the eradication of Polio and Smallpox. The current pandemic underscores the need for an effective vaccine ever so. In the last ten months, life has changed drastically around the world. With the pandemic raging on and no cure in sight, it is clear that vaccines are a critical component of public …

Applying Immuno-Epidemiology Principles To Violence, Anna H. Sisk, Nina H. Fefferman, Judy Day, Patricia Bamwine

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Various Mathematical Models To Study Covid-19 Pandemic Dynamics With Quarantine, Hospitalized And Non-Pharmaceutical Interventions As Control Strategies, Amit Sharma, Bhanu Gupta

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Stochastic Analysis And Statistical Inference For Seir Models Of Infectious Diseases, Andrés Ríos-Gutiérrez, Viswanathan Arunachalam, Anuj Mubayi

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

The Effect Of Fcgammariia Polymorphisms On Dengue Outbreak Severity, Leah Darwin, Richard V. Clarke

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Modeling And Preparedness: The Transmission Dynamics Of Covid-19 Outbreak In Provinces Of Ecuador, Carlos E. Bustamante Orellana, Jordy Cevallos-Chavez, Cesar Montalvo, Jeff Sulliavan, Edwin Michael, Anuj Mubayi

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

A Regional Model For Projecting Covid-19 In Northern Mindanao, Philippines, Jayrold P. Arcede

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

A Mathematical Model Of The Effect Of Social Distancing On The Spread Of Covid-19, Anna Singley, Hannah Callender Highlander

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

In Silico Modelling For The Treatment Of Gastric Cancer, Leonardo F. Martinez, Diana Gamboa, Paul A. Valle

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Mathematical Modelling And In Silico Experimentation To Estimate The Quantity Of Covid-19 Infected Individuals In Tijuana, México, Karla A. Encinas, Luis N. Coria, Paul A. Valle

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Mobility Impact In The Spreading Of Covid-19 In Ecuador, Jordy Cevallos-Chavez, Carlos E. Bustamante Orellana, Cesar Montalvo, Anuj Mubayi, Edwin Michael, Edwin Michael

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Differences In Gut Microbiome In Hospitalized Immunocompetent Vs. Immunocompromised Children, Including Those With Sickle Cell Disease., Sindhu Mohandas, Vijaya L Soma, Thi Dong Binh Tran, Erica Sodergren, Tresa Ambooken, David L Goldman, George M. Weinstock, Betsy C Herold

Faculty Research 2020

Background: Gut microbial diversity and composition play important roles in health. This cross-sectional study was designed to test the hypothesis that hospitalized children who may be relatively immunocompromised (IC), defined as those with cancer, sickle cell disease (SCD), transplantation, or receiving immunosuppressive therapy) would have decreased microbial diversity, increased Clostridioides difficile colonization and different species composition compared to non-immunocompromised (Non-IC) children admitted to the same pediatric unit. Methods: A stool sample was obtained within 72 h of admission to a single unit at The Children's Hospital at Montefiore, Bronx, NY from March 2016 to February 2017 and the microbiome assessed …

Conquer And Prevail Issue 40 Nov 12 2020, Wofford College. Office Of Marketing And Communications

Conquer and Prevail Newsletter

No abstract provided.

How Can You Safely Return Home For The Holidays?, Alicia Rohan

Browse All News

No abstract provided.

The Cowl - V.85 - N.6 - Nov 12, 2020

The Cowl

The Cowl - student newspaper of Providence College. Volume 85 No. 6 - November 12, 2020. 24 pages.

Spatial And Temporal Determinants Associated With Eastern Equine Encephalitis Virus Activity In Florida, Kristi M. Miley

USF Tampa Graduate Theses and Dissertations

Eastern Equine Encephalitis virus (EEEV) is considered the most pathogenic mosquito-borne illness in the United States. Human mortality has been estimated to range between 35 to 75%, with horses experiencing mortality rates greater than 90%. A large number of EEEV cases occur in Florida. Though we have come a long way since the first human infection was identified in the 1930s, there is still much to learn regarding the virus’s ability to maintain transmission year-round in Florida. Phylogenic studies support that Florida may serve as the geographic reservoir for EEEV. This research investigated spatiotemporal and ecological variables associated with risk …

Coronavirus Research Output During 2001-2020: A Scientometrics Analysis, Lambodara Parabhoi, Dr. Manoj Kumar Verma

Library Philosophy and Practice (e-journal)

COVID-19 virus originated from Wuhan city of China in December 2019. The emergence of COVID-19 the whole world and severely affected by The United States, China, Brazil, and India etc.. World Health Organization (WHO) declared it as a pandemic in March 2020. Due to COVID-19, a large number of literature published in early 2020. However, very few studies address the impact of published related to literature Coronavirus. In response to the current study conducted and reviewed 20 years' period from 2001- May 2020. A total of 14439 documents were found in the Scopus database, which was published during the study …

Patient Engagement In Action: Timing And Intensity Of Strategies Used To Engage Low Income Depressed Mothers Of Infants And Toddlers, Maureen J. Baker, Beth Perry Black, Linda S. Beeber

Patient Experience Journal

The purpose of this study was to illuminate the process of patient engagement and to determine how components of patient engagement were operationalized in the nurse-patient interpersonal relationship with low income, depressed mothers, a traditionally underserved population. Using a descriptive quantitative design, we examined how components of patient engagement were executed across three phases of the nurse-patient interpersonal relationship. We assessed for differences in engagement strategies used in different phases of the interpersonal relationship and with mothers with varying levels of engagement. Through this study, we observed that patient engagement has several dynamic components varying in intensity and frequency, depending …