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2020-11-18_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Carbapenemase Screening In An Irish Tertiary Referral Hospital: Best Practice, Or Can We Do Better?, Sinéad Fahy, J. A. O'Connor, D. O'Brien, L. Fitzpatrick, M. O'Connor, J. Crowley, M. Bernard, Roy D. Sleator, Brigid Lucey

Department of Biological Sciences Publications

Initially, United States Centre of Disease Control (CDC) recommended culture-based CPE screens; using broth enrichment in tryptone soy broth (TSB), followed by culture onto MacConkey agar with a carbapenem disc. However, this protocol is both time consuming (approx. 48hrs) and labour intensive, making it impractical for routine screening, particularly in a busy hospital laboratory [10]. Some improvements have been observed using commercially available culture plates, particularly in terms of decreased turnaround times (approx. 24hrs) and increased sensitivity/specificity for CPE producers; mSuperCarba (CHROMagar) media, for example has shown an increased sensitivity rate of 83% compared to 69% for MacConkey culture with …

Survey Contributes To Ehr Changes; Promotes User Well-Being, Mary Ashley Canevaro

Browse All News

No abstract provided.

Evaluation Of The Xpert Carba-R Nxg Assay For Detection Of Carbapenemase Genes In A Global Challenge Set Of Pseudomonas Aeruginosa Isolates, Fred C. Tenover, Christian M. Gill, Tomefa E. Asempa, Isabella A. Tickler, Caitlin M. Dela Cruz, David P. Nicolau

Biology Faculty Publications

The growing prevalence and diversity of carbapenemase producers among carbapenem-resistant Pseudomonas aeruginosa (CRPA) isolates warrants an expansion of detection capabilities. The purpose of this study was to evaluate the performance of the commercially available Xpert Carba-R (Carba-R) and the research-use-only Xpert Carba-R NxG (Carba-R NxG) in a global collection of P. aeruginosa. The challenge set included 123 P. aeruginosa clinical isolates from 12 countries. Isolates were previously categorized via PCR or whole-genome sequencing. Carbapenemase classes tested include VIM, IMP, NDM, SPM, KPC, and GES. Non-carbapenemase (non-CP)-harboring isolates were also tested (negative control). Isolates were tested using the Carba-R NxG and …

Performance Of Lung Ultrasound In The Diagnosis Of Pediatric Pneumonia In Mozambique And Pakistan, Amy Sarah Ginsburg, Jennifer L. Lenahan, Fyezah Jehan, Rubao Bila, Alessandro Lamorte, Jun Hwang, Lola Madrid, Muhammad Imran Nisar, Benazir Baloch, Naila Nadeem

Department of Paediatrics and Child Health

Introduction: Improved pneumonia diagnostics are needed in low-resource settings (LRS); lung ultrasound (LUS) is a promising diagnostic technology for pneumonia. The objective was to compare LUS versus chest radiograph (CXR), and among LUS interpreters, to compare expert versus limited training with respect to interrater reliability.
Methods: We conducted a prospective, observational study among children with World Health Organization (WHO) Integrated Management of Childhood Illness (IMCI) chest-indrawing pneumonia at two district hospitals in Mozambique and Pakistan, and assessed LUS and CXR examinations. The primary endpoint was interrater reliability between LUS and CXR interpreters for pneumonia diagnosis among children with WHO IMCI …

Multiparametric Profiling Of Engineered Nanomaterials: Unmasking The Surface Coating Effect, A Gallud, M Delaval, P Kinaret, Vs Marwah, V Fortino, J Ytterberg, R Zubarev, T Skoog, J Kere, M Correia, K Loeschner, Z Al‐Ahmady, K Kostarelos, J Ruiz, D Astruc, M Monopoli, R Handy, S Moya, K Savolainen, H Alenius, D Greco, B Fadeel

School of Biological and Marine Sciences

No abstract provided.

Rural Appalachia Battling The Intersection Of Two Crises: Covid-19 And Substance Use Disorders, Margaret Miller, Rebekah Rollston, Kate E. Beatty, Michael Meit

Journal of Appalachian Health

During the COVID-19 pandemic, rural Appalachia is at great risk of unforeseen side effects including increased mortality from substance use disorders (SUDs). People living with SUDs are at increased risk for both exposure to and poor outcomes from COVID infection. The economic impacts of COVID-19 must also be considered. As rural Appalachia combats the substance use crisis amidst the COVID-19 pandemic, the geographic economic, health and social inequities within our region must be considered. As a national recovery is sought, we should reimagine federal policies that center the economic and public health of rural Appalachia addressing the two crises.

In Their Own Words: How Opioids Have Impacted The Lives Of “Everyday” People Living In Appalachia, Patricia Nola Eugene Roberson, Gina Cortez, Laura H. Trull, Katherine Allison Lenger

Journal of Appalachian Health

Introduction: The opioid epidemic is ravaging people, families, and communities in Appalachia. However, limited research has examined how “everyday” people (e.g., not chronic pain patients, not medical professionals) living in these communities how opioids have impacted their lives.

Objective: Identify the perception of the opioid epidemic on individuals, families, and communities from people living in region most impacted regions.

Methods: Patients were recruited at Remote Area Medical clinics throughout Central and Southern Appalachia to complete interviews online (N = 169) or over the phone (N = 26), including one open-ended question about how opioids have impacted their lives.

Results: Using …

Medical Social Science And Clinical Decision Science, James Peter Meza

Clinical Research in Practice: The Journal of Team Hippocrates

Exploring the curricular link between Medical Social Science and Clinical Decision Science in the development of a physician.

Selective Interactions Of O-Methylated Flavonoid Natural Products With Human Monoamine Oxidase-A And -B, Narayan D. Chaurasiya, Jacob Midiwo, Pankaj Pandey, Regina N. Bwire, Robert J. Doerksen, Ilias Muhammad, Babu L. Tekwani

Faculty and Student Publications

A set of structurally related O-methylated flavonoid natural products isolated from Senecio roseiflorus (1), Polygonum senegalense (2 and 3), Bhaphia macrocalyx (4), Gardenia ternifolia (5), and Psiadia punctulata (6) plant species were characterized for their interaction with human monoamine oxidases (MAO-A and -B) in vitro. Compounds 1, 2, and 5 showed selective inhibition of MAO-A, while 4 and 6 showed selective inhibition of MAO-B. Compound 3 showed ~2-fold selectivity towards inhibition of MAO-A. Binding of compounds 1-3 and 5 with MAO-A, and compounds 3 and 6 with MAO-B was reversible and not time-independent. The analysis of enzyme-inhibition kinetics suggested a …

Ua12/2/1 College Heights Herald, Vol. 96, No. 13, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

• Burned Out – COVID-19
• Payne, Michael. 15 Years with the Bagel Brothers – Sandra Hurley
• Hargrove, Matthew. Hilltoppers Get in the Win Column, Home Finale Up Next - Football
• Kieser, Nick. All Eyes on the Spring – Basketball, Softball, Soccer, Baseball
• Leboutier, Addison. Little Flock of Jesus Christ Fellowship Comes Home – Clarence Tapp
• Cox, Alex. Editorial Cartoon re: Kamala Harris
• What a Kamala Harris Vice Presidency Means for Young People of Color
• Lattimer, Jacob. Student Government Association Sustainability Committee Looks to Make an Impact …

2020-11-17_Michiganoverview_Covidtestingtimes, Michigan Department Of Health & Human Services

Michigan COVID-19 Testing Turnaround Data

The COVID Testing Turnaround Time page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-545615--,00.html.

This report was created by the Michigan Department of Health & Human Services, providing data for the past 14 days on the average time it takes for a diagnostic COVID-19 laboratory test to be reported to the state health department.

MDHHS receives results from commercial labs, hospitals, and public health labs. However, public health laboratories perform limited diagnostic testing and disease surveillance for infectious diseases. Total turnaround time is calculated from the difference of the date of the collection of a sample for diagnostic testing …

2020-11-17_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Inspiring Teamwork During Unprecedented Times, Selwyn M. Vickers Md

Browse All News

No abstract provided.

Daily Eastern News: November 17, 2020, Eastern Illinois University

November

No abstract provided.

An Ulk1-Independent Mechanism Of Atg9a Regulation In Basal Autophagy, Ashari Rashmi Kannangara

Theses and Dissertations

Macroautophagy (hereafter referred to as autophagy) is the bulk degradation and recycling of cytoplasmic materials by forming a double membrane vesicle called the autophagosome. Autophagosome formation is regulated by the coordinated action of a set of proteins. ATG9A is the only multispanning transmembrane protein that plays an essential role in autophagosome formation, yet its function is largely elusive. Previous studies have shown that the C-terminus of ATG9A plays an important role in regulating its trafficking and proper function in autophagy. In line with that idea, we previously identified an AMPK- and ULK1- mediated phosphorylation on the C terminus of ATG9A …

Acing The Test, Keith Testa

UNH Today Archive

No abstract provided.

Gastrointestinal Parasites In The Neotropical Otter (Lontra Longicaudis Annectens) In Central Mexico, Erika Y. Badillo Flores, Marcos G. Torres Tobón, C. Gustavo Aguilar Cabrera, O. Eric Ramírez-Bravo, Eva Romero Callejas

Western North American Naturalist

We analyzed 47 scats of neotropical otter (Lontra longicaudis annectens), collected along the Necaxa River in Central Mexico, using the Willis flotation technique with a 48% saturated saline solution. Along with plant material, we found the endoparasites Oxyuris equi, Ascaris sp., and Strongylus equinus, among others. Our results indicate that otters in the Necaxa River have a parasite load that needs further analysis, particularly because 2 of the parasite species are associated with human activity.


Analizamos 47 excretas de nutria neotropical (Lontra longicaudis annectens), colectadas a lo largo del Río Necaxa en el Centro …

Impact Of Coronavirus Disease 2019 Pandemic On The Incidence And Management Of Out-Of-Hospital Cardiac Arrest In Patients Presenting With Acute Myocardial Infarction In England., Muhammad Rashid Hons, Chris P. Gale Hons, Nick Curzen Hons, Peter Ludman Hons, Mark De Belder Hons, Adam Timmis Hons, Mohamed O Mohamed Hons, Thomas F Lüscher Hons, Julian Hains Hons, Jianhua Wu, Ahmad Shoaib, Evangelos Kontopantelis, Chris Roebuck, Tom Denwood, John Deanfield, Mamas A. Mamas

Department of Medicine Faculty Papers

Background Studies have reported significant reduction in acute myocardial infarction-related hospitalizations during the coronavirus disease 2019 (COVID-19) pandemic. However, whether these trends are associated with increased incidence of out-of-hospital cardiac arrest (OHCA) in this population is unknown. Methods and Results Acute myocardial infarction hospitalizations with OHCA during the COVID-19 period (February 1-May 14, 2020) from the Myocardial Ischaemia National Audit Project and British Cardiovascular Intervention Society data sets were analyzed. Temporal trends were assessed using Poisson models with equivalent pre-COVID-19 period (February 1-May 14, 2019) as reference. Acute myocardial infarction hospitalizations during COVID-19 period were reduced by >50% (n=20 310 …

Conduct Of Clinical Trials In The Era Of Covid-19: Jacc Scientific Expert Panel., Mitchell A. Psotka, William T. Abraham, Mona Fiuzat, Gerasimos Filippatos, Joann Lindenfeld, Tariq Ahmad, Ankeet S. Bhatt, Peter E. Carson, John G.F. Cleland, G. Michael Felker, James L. Januzzi, Dalane W. Kitzman, Eric S. Leifer, Eldrin F. Lewis, John J.V. Mcmurray, Robert J. Mentz, Scott D. Solomon, Norman Stockbridge, John R. Teerlink, Muthiah Vaduganathan, Orly Vardeny, David J. Whellan, Janet Wittes, Stefan D. Anker, Christopher M. O'Connor

Department of Medicine Faculty Papers

The coronavirus disease-2019 (COVID-19) pandemic has profoundly changed clinical care and research, including the conduct of clinical trials, and the clinical research ecosystem will need to adapt to this transformed environment. The Heart Failure Academic Research Consortium is a partnership between the Heart Failure Collaboratory and the Academic Research Consortium, composed of academic investigators from the United States and Europe, patients, the U.S. Food and Drug Administration, the National Institutes of Health, and industry members. A series of meetings were convened to address the challenges caused by the COVID-19 pandemic, review options for maintaining or altering best practices, and establish …

Research Support Services Of Panjab University Library During Lockdown Period Due To Covid-19: A Survey, Suman Sumi, Jatinder Kumar

Library Philosophy and Practice (e-journal)

The study explores the problems and prospects of newly introduced service “RemoteXs” by the A.C. Joshi library for the faculty of Panjab University during the lockdown due to COVID-19. The paper discusses expectations and experiences of users, advantages of new research support services, challenges faced by faculty while accessing literature through RemoteXs service. An online survey was carried out; framed questionnaire was sent to 650 academicians through Whatsapp and e-mail. 148 respondents submitted their views on access and usage of e-resources through RemoteXs service of University Library. Data on most frequently used resources and documents type has been analysed. Some …

November 16, 2020: Letter From The President- Covid-19 Update, Kettering University

Communication Updates

No abstract provided.

2020-11-16_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Keep Moving And Stay Connected: Tips For Taking Care Of Older Loved Ones During A Pandemic, Adam Pope

Browse All News

No abstract provided.

Daily Eastern News: November 16, 2020, Eastern Illinois University

November

No abstract provided.

Interleukin-17a Facilitates Chikungunya Virus Infection By Inhibiting Ifn-Α2 Expression, Biswas Neupane, Dhiraj Acharya, Farzana Nazneen, Gabriel Gonzalez-Fernandez, Alex Sutton Flynt, Fengwei Bai

Faculty Publications

Interferons (IFNs) are the key components of innate immunity and are crucial for host defense against viral infections. Here, we report a novel role of interleukin-17A (IL-17A) in inhibiting IFN-α2 expression thus promoting chikungunya virus (CHIKV) infection. CHIKV infected IL-17A deficient (Il17a^−/−) mice expressed a higher level of IFN-α2 and developed diminished viremia and milder footpad swelling in comparison to wild-type (WT) control mice, which was also recapitulated in IL-17A receptor-deficient (Il17ra^−/−) mice. Interestingly, IL-17A selectively blocked IFN-α2 production during CHIKV, but not West Nile virus (WNV) or Zika virus (ZIKV), infections. Recombinant IL-17A …

An Agent-Based Simulator For The Gastrointestinal Pathway Of Listeria Monocytogenes, Ashrafur Rahman, Ali Asgary, Daniel Munther, Aamir Fazil, Ben A. Smith, Jianhong Wu

Mathematics and Statistics Faculty Publications

We developed an agent-based gastric simulator for a human host to illustrate the within host survival mechanisms of Listeria monocytogenes. The simulator incorporates the gastric physiology and digestion processes that are critical for pathogen survival in the stomach. Mathematical formulations for the pH dynamics, stomach emptying time, and survival probability in the presence of gastric acid are integrated in the simulator to evaluate the portion of ingested bacteria that survives in the stomach and reaches the small intestine. The parameters are estimated using in vitro data relevant to the human stomach and L. monocytogenes. The simulator predicts that 5%–29% of …

Challenges Facing Young Scientists In Academia And Industry In The United States From The Lens Of A Millennial Academic, Joseph R. Clark

Biological Sciences Faculty Research and Publications

Rising to the challenge: Pictured from left to right: Salma L. Nuñez, Albert Reyes and Lisandra Santiago-Capeles, Ph.D. The challenges that young scientists face in academia and industry in the United States are discussed. Prof. Joseph Clark provides insight about how social media, funding, diversity, natural disasters, COVID-19 and student loan debt are impacting young scientists. A discussion of strategies to meet these challenges and support young scientists are presented.

Week Of November 16, 2020, New York Medical College

InTouch

• Clinical Skills and Simulation Center Purchases Pediatric Emergency Airway Management Task Trainers with the Support of The Children's Dream Foundation
• Faculty and Students Publish Study Demonstrating that Black Seed Oil Plus Omega-3s May Counter Obesity-Induced Inflammation and Insulin Resistance
• Middle States Re-accreditation Update
• Faculty Spotlight: George W. Contreras, M.P.H., M.S., M.E.P., CEM, FACEM

Efficacy Of Phytochemicals In Inhibiting Horizontal Gene Transfer Of Antibiotic Resistance Between Multidrug Resistant Salmonella And Commensal E. Coli, Poonam Vinayamohan

Doctoral Dissertations

Bacterial antibiotic resistance (AR) imposes a huge threat to public health worldwide. Overuse and misuse of antibiotics in human medicine and animal agriculture resulted in the development of antibiotic resistant bacteria, including pathogens. Bacteria possess an inherent ability to share their genetic information by means of horizontal gene transfer (HGT), a property that favors dissemination of AR genes among neighboring bacteria. The animal gut, the reservoir of AR bacteria and AR genes, acts as a source for environmental contamination and propagation of AR through manure and water. There has been an increased incidence of AR Salmonella infections in humans in …