Digital Commons Network^™

Covid-19 Presenting As Acute Hepatitis, P. Wander, M. Epstein, D. Bernstein

Journal Articles

No abstract provided.

A Case Of Vancomycin-Induced Immune Thrombocytopenia., K. N. Macdougall, S. Parylo, A. Sokoloff

Journal Articles

Vancomycin-induced immune thrombocytopenia (ITP) is a rare, potentially life-threatening complication from an antibiotic frequently used in medical practice. We report a case of an 81-year-old male with recent removal of an infected right knee prosthesis and insertion of an articulating antibiotic spacer, presenting from rehabilitation for severe thrombocytopenia (1 X 103/µL). The patient's thrombocytopenia was initially falsely attributed to rifampin-induced ITP, a much more common cause of drug-induced thrombocytopenia. Only later, after a second precipitous drop in platelet count, vancomycin was correctly identified as the culprit. The patient's serum was tested for drug-dependent platelet antibodies with and without vancomycin. A …

A Case Of Listeria Monocytogenes Meningitis Complicated By Hydrocephalus And Intraventricular Hemorrhage: A Review Of Treatment Options And Outcomes, S. Gerstein, P. Gautam-Goyal, S. Goyal

Journal Articles

© 2020 The Authors Listeria monocytogenes is a gram-positive bacillus known to cause various human infections including central nervous system infections. The most common central nervous system manifestations are meningitis and rhomboencephalitis, however rare complications including hydrocephalus and intracerebral hemorrhage can occur and are associated with increased mortality and incidence of lasting neurologic sequelae. The mortality ranges from 17 % to greater than 30 % in patients with neurological involvement [1–3]. Various case reports have studied the differing treatment approaches and outcomes of patients who experienced these complications, and there is still no consensus on optimal treatment approaches. In this …

New Paradigms Of Extended Thromboprophylaxis In Medically Ill Patients, K. Macdougall, A. C. Spyropoulos

Journal Articles

No abstract provided.

Scientific And Standardization Committee Communication: Clinical Guidance On The Diagnosis, Prevention And Treatment Of Venous Thromboembolism In Hospitalized Patients With Covid-19., A. C. Spyropoulos, J. H. Levy, W. Ageno, J. M. Connors, B. J. Hunt, T. Iba, M. Levi, C. M. Samama, D. Giannis, +2 Additional Authors

Journal Articles

The novel coronavirus disease of 2019 (COVID-19) pandemic, as declared by the World Health Organization, is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). Cardiovascular disease and, in particular, venous thromboembolism (VTE) has emerged as an important consideration in the management of hospitalized patients with COVID-19. The diagnosis of VTE using standardized objective testing is problematic in these patients, given the risk of infecting non-COVID-19 hospitalized patients and hospital personnel, coupled with the usual challenges of performing diagnostic testing in critically-ill patients. Early reports suggest a high incidence of VTE in hospitalized COVID-19 patients, particularly those with severe …

Comparison Of Four Molecular In Vitro Diagnostic Assays For The Detection Of Sars-Cov-2 In Nasopharyngeal Specimens., W Zhen, R Manji, E Smith, Gj Berry

Journal Articles

No abstract provided.

Covid-19 Presenting As Stroke, A. Avula, K. Nalleballe, N. Narula, S. Sapozhnikov, V. Dandu, S. Toom, A. Glaser, D. Elsayegh

Journal Articles

© 2020 Elsevier Inc. Objective: Acute stroke remains a medical emergency even during the COVID-19 pandemic. Most patients with COVID-19 infection present with constitutional and respiratory symptoms; while others present with atypical gastrointestinal, cardiovascular, or neurological manifestations. Here we present a series of four patients with COVID-19 that presented with acute stroke. Methods: We searched the hospital databases for patients that presented with acute stroke and concomitant features of suspected COVID-19 infection. All patients who had radiographic evidence of stroke and PCR-confirmed COVID-19 infection were included in the study. Patients admitted to the hospital with PCR- confirmed COVID-19 disease whose …

Arterial Thromboembolic Complications In Covid-19 In Low-Risk Patients Despite Prophylaxis, D. O. Griffin, A. Jensen, M. Khan, J. Chin, K. Chin, R. Parnell, C. Awwad, D. Patel

Journal Articles

No abstract provided.

Faith Integration Essay: Biblical And Theological Studies, Victor I. Ezigbo

Faith Learning Integration Papers

This essay discusses two major themes, "Faith, Theology, and Guiding Principles for Theological Reflection" and "Christian Gospel and the Public Sphere".

The introduction begins as follows, "The term ‘faith’ is notoriously slippery. Theologians as well as Christians who do not have any formal theological education use the term ‘faith’ sometimes in competing ways. For example, some use ‘faith’ as a shield for protecting themselves from people who ask questions about God’s existence and actions in the world. For such people, faith opposes reason. They see ‘faith’ as “an antithesis of reason” and also construe “reason as an intellectual virus that …

7th–8th Grade: English Level 3, Learning Packet #3 • Theme: Disasters #3, Caryn G. Jones, Lauren Gatti, Alexa Yunes

ICMEE Learning Packets: Level 3 of English Proficiency (K-12)

Pandemic! Grades 7-8

Understanding the COVID-19 Pandemic

Lesson 1 • Define and classify diseases, Reflections

Lesson 2 • Psssttt...DON'T pass it on, Reflections

Lesson 3 • GROSS...anatomy (It's not really gross!), Systems of the human body, How do you feel?, Reflections

Lesson 4 • Treatment vs cure vs vaccine, Symptoms can be beneficial, Diagnose it, doctor!, Beyond diagnosis, Use your knowledge: Diagnose and treat, Reflections

My Packet Journal

Reference Sheet

Answer Keys

University Of Texas Health Science Center At Tyler Catalog, 2020 - 2022, University Of Texas Health Science Center At Tyler

Catalogs

No abstract provided.

Effect Of Silver Diamine Fluoride On Candida Albicans Associated With Early Childhood Caries, Sarah Al Kukash

Student Theses, Dissertations and Capstones

BACKGROUND: Early childhood caries (ECC) is one of the most prevalent infectious diseases in childhood worldwide. It afflicts 23% of the preschoolers in the U.S. It most frequently targets children from poor socioeconomic families and racial/ethnic minority backgrounds and becomes a serious public health problem. The major pathogen of ECC is Streptococcus mutans (S. mutans). However, the occurrence of ECC is positively associated with the presence of Candida albicans (C. albicans). It is well established that Silver Diamine Fluoride (SDF), a recent Food and Drug Administration (FDA)-off labeled approved agent for arresting dental caries, exhibits a robust antibacterial effect on …

Ethical Imperatives Critical To Effective Disease Control In The Coronavirus Pandemic: Recognition Of Global Health Interdependence As A Driver Of Health And Social Equity, George A. Gellert Md, Mph, Mpa

Journal of Health Ethics

Ethical imperatives critical to effective disease control in the coronavirus pandemic: Recognition of global health interdependence as a driver of health and social equity

George A. Gellert MD, MPH, MPA

ABSTRACT

Decades into the era of emerging infectious diseases, the 2019-2020 coronavirus pandemic has caught the world, and the United States in particular, poorly prepared to engage effective public health disease prevention and control measures. In part, this reflects poor public health planning, response, logistical preparation and pandemic readiness, and complacency by governments and disease control agencies. In terms of future responses to emerging infection pandemics, these deficiencies can be …

Tufts Analytics Without Borders 2020 Conference Conference Summary Report, Tufts University

Analytics Without Borders

This conference provided a single venue for interdisciplinary research, collaboration, and communication on applied data analytics in the fields of business, public health, nutrition, and the environment. We advanced a shared agenda to harness the power of data sciences to discuss the complexities of health and nutrition problems through the lens of data sciences. The conference showcased numerous opportunities for students including hands-on workshops on topics related to data sciences, panel discussions on topics ranging from business to health, and both oral and poster presentations for sharing research.

The Effectiveness Of Italian Law 104/92: Healthcare For Pediatric Physical Disabilities, Claudia Heim

CISLA Senior Integrative Projects

No abstract provided.

Stability Analysis Of A Waterborne Infectious Disease Model With Infectious Saturation Effect On Bacterial Disease Transmission, Cemil Bu ̈Yu ̈Kadalı

Applied Mathematics & Information Sciences

This paper considers a waterborne infectious disease model with infectious saturation effect on bacterial disease transmission. For this model we find sufficient conditions for global stability of disease free equilibrium. We verify the result using appropriate numerical simulations.

Osteopathic Medicine Program 2020, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Interrupted Blood Feeding In Ticks: Causes And Consequences, Djamel Tahir, Leon Meyer, Josephus Fourie, Frans Jongejan, Thomas N. Mather, Valérie Choumet, Byron Blagburn, Reinhard K. Straubinger, Marie Varloud

Plant Sciences and Entomology Faculty Publications

Ticks are obligate hematophagous arthropods and act as vectors for a great variety of pathogens, including viruses, bacteria, protozoa, and helminths. Some tick-borne viruses, such as Powassan virus and tick-borne encephalitis virus, are transmissible within 15–60 min after tick attachment. However, a minimum of 3–24 h of tick attachment is necessary to effectively transmit bacterial agents such as Ehrlichia spp., Anaplasma spp., and Rickettsia spp. to a new host. Longer transmission periods were reported for Borrelia spp. and protozoans such as Babesia spp., which require a minimum duration of 24–48 h of tick attachment for maturation and migration of the …

What Is The Future Of Organoids?, Michelle Freilich

The Science Journal of the Lander College of Arts and Sciences

The term organoid refers to a miniature version of any organ of the body. An organoid is artificially produced in vitro from stem cells or tissue that possess the ability to recapitulate and form the three-dimensional structure of the organ they were once a part of. Scientists have learned to create a culture for the organoid that mimics its original micro cellular environment, allowing the 3-D structure to self-organize and develop into miniature organs. The purpose of this paper is to explore the many advancements of organoid technology, and how this progress has benefited the medical field. Organoid technology allows …

Research And Creative Activity, July 1, 2019-June 30, 2020: Major Sponsored Programs And Faculty Accomplishments In Research And Creative Activity, University Of Nebraska-Lincoln, Office Of Research And Economic Development, University Of Nebraska–Lincoln

Office of Research and Economic Development: Publications

Foreword by Bob Wilhelm, Vice Chancellor for Research and Economic Development:

This booklet highlights successes in research, scholarship and creative activity by University of Nebraska–Lincoln faculty during the fiscal year running July 1, 2019, to June 30, 2020.

It lists investigators, project titles and funding sources on major grants and sponsored awards received during the year; fellowships and other recognitions and honors bestowed on our faculty; books published by faculty; performances, exhibitions and other creative activity; and patents and licensing agreements issued. Based on your feedback, the Office of Research and Economic Development expanded this publication to include peer-reviewed journal …

European Heart Rhythm Association (Ehra) International Consensus Document On How To Prevent, Diagnose, And Treat Cardiac Implantable Electronic Device Infections - Endorsed By The Heart Rhythm Society (Hrs), The Asia Pacific Heart Rhythm Society (Aphrs), The Latin American Heart Rhythm Society (Lahrs), International Society For Cardiovascular Infectious Diseases (Iscvid) And The European Society Of Clinical Microbiology And Infectious Diseases (Escmid) In Collaboration With The European Association For Cardio-Thoracic Surgery (Eacts), C. Blomström-Lundqvist, V. Traykov, P. A. Erba, H. Burri, J. C. Nielsen, M. G. Bongiorni, J. Poole, G. Boriani, L. M. Epstein, E. Mangoni, +10 Additional Authors

Journal Articles

© 2019 The Author(s). Published by Oxford University Press on behalf of the European Society of Cardiology. Pacemakers, implantable cardiac defibrillators, and cardiac resynchronization therapy devices are potentially life-saving treatments for a number of cardiac conditions, but are not without risk. Most concerning is the risk of a cardiac implantable electronic device (CIED) infection, which is associated with significant morbidity, increased hospitalizations, reduced survival, and increased healthcare costs. Recommended preventive strategies such as administration of intravenous antibiotics before implantation are well recognized. Uncertainties have remained about the role of various preventive, diagnostic, and treatment measures such as skin antiseptics, pocket …

Hrs/Ehra/Aphrs/Lahrs/Acc/Aha Worldwide Practice Update For Telehealth And Arrhythmia Monitoring During And After A Pandemic., N. Varma, N. F. Marrouche, L. Aguinaga, C. M. Albert, E. Arbelo, J. Choi, M. K. Chung, G. Conte, L. M. Epstein, P. D. Varosy, +13 Additional Authors

Journal Articles

No abstract provided.

Covid-19 In Children: More Than Meets The Eye, Sh F. Hagmann

Journal Articles

No abstract provided.

Cll Intraclonal Fractions Exhibit Established And Recently Acquired Patterns Of Dna Methylation, B. A. Bartholdy, X. Wang, X. Yan, M. Pascual, M. Fan, J. Barrientos, S. L. Allen, K. R. Rai, N. Chiorazzi, S. Roa, +2 Additional Authors

Journal Articles

No abstract provided.

Elevated Liver Biochemistries In Hospitalized Chinese Patients With Severe Covid-19: Systematic Review And Meta-Analysis., A. J. Kovalic, G. Huang, P. J. Thuluvath, S. K. Satapathy

Journal Articles

BACKGROUND & AIMS:Several recent studies have reported an abnormal liver chemistry profile among patients with coronavirus disease 2019 (COVID-19), although its clinical significance remains unknown. APPROACH & RESULTS:This novel systematic review and meta-analysis identified six studies of 586 patients delineating liver chemistries among patients with severe/critical illness versus mild cases of COVID-19 infection. Patients with severe/critical illness with COVID-19 infection have increased prevalence of coronary artery disease (CAD), cerebrovascular disease, and chronic obstructive pulmonary disease (COPD) as compared to mild cases. A significant association between severe/critical COVID-19 infections with elevations in aspartate aminotransferase (AST) (pooled mean difference [MD], 11.70 U/L; …

General And Intensive Care Outcomes For Hospitalized Patients With Solid Organ Transplants With Covid-19, F. Mastroianni, D. E. Leisman, G. Fisler, M. Narasimhan

Journal Articles

© The Author(s) 2020. Purpose: COVID-19 has been associated with a dysregulated inflammatory response. Patients who have received solid-organ transplants are more susceptible to infections in general due to the use of immunosuppressants. We investigated factors associated with mechanical ventilation and outcomes in solid-organ transplant recipients with COVID-19. Materials and Methods: We conducted a retrospective cohort study of all solid-organ transplant recipients admitted with a diagnosis of COVID-19 in our 23-hospital health system over a 1-month period. Descriptive statistics were used to describe hospital course and laboratory results and bivariate comparisons were performed on variables to determine differences. Results: Twenty-two …

Use Of Tetanus Toxoid, Reduced Diphtheria Toxoid, And Acellular Pertussis Vaccines: Updated Recommendations Of The Advisory Committee On Immunization Practices - United States, 2019, F. P. Havers, P. L. Moro, P. Hunter, S. Hariri, H. Bernstein

Journal Articles

No abstract provided.

Molecular Testing For Acute Respiratory Tract Infections: Clinical And Diagnostic Recommendations From The Idsa's Diagnostics Committee., K. E. Hanson, M. M. Azar, R. Banerjee, A. Chou, R. C. Colgrove, C. C. Ginocchio, M. K. Hayden, M. Holodiny, S. Jain, Diagnostics Committee Of The Infectious Diseases S, +4 Additional Authors

Journal Articles

The clinical signs and symptoms of acute respiratory tract infections (RTIs) are not pathogen specific. Highly sensitive and specific nucleic acid amplification tests have become the diagnostic reference standard for viruses and translation of bacterial assays from basic research to routine clinical practice represents an exciting advance in respiratory medicine. Most recently, molecular diagnostics have played an essential role in the global health response to the novel coronavirus pandemic. How best to use newer molecular tests for RTI in combination with clinical judNorthwell Healthnt and traditional methods can be bewildering given the plethora of available assays and rapidly evolving technologies. …

Obesity And Sting1 Genotype Associate With 23-Valent Pneumococcal Vaccination Efficacy, M. Sebastian, C. J. Hsiao, H. S. Futch, R. S. Eisinger, L. Dumeny, S. Patel, M. Gobena, D. S. Katikaneni, L. Spiryda, M. L. Brantly, +4 Additional Authors

Journal Articles

© 2020, Sebastian etal. BACKGROUND. Obesity has been associated with attenuated vaccine responses and an increased risk of contracting pneumococcal pneumonia, but no study to our knowledge has assessed the impact of obesity and genetics on 23-valent pneumococcal vaccine (PPSV23) efficacy. We assessed the relationship of obesity (primary analysis) and stimulator of interferon genes (STING1) genotype (secondary analysis) on PPSV23 efficacy. METHODS. Nonobese (BMI 22-25 kg/m2) and obese participants (BMI ≥30 kg/m2) were given a single dose of PPSV23. Blood was drawn immediately prior to and 4-6 weeks after vaccination. Serum samples were used to assess PPSV23-specific antibodies. STING1 genotypes …

A Modified Delphi Study To Prioritize Content For A Simulation-Based Pediatric Curriculum For Emergency Medicine Residency Training Programs, J. Mitzman, I. Bank, R. A. Burns, M. C. Nguyen, P. Zaveri, M. J. Falk, M. Madhok, A. Dietrich, F. M. Bullaro, M. Auerbach, +9 Additional Authors

Journal Articles

© 2019 by the Society for Academic Emergency Medicine Objectives: Pediatric training is an essential component of emergency medicine (EM) residency. The heterogeneity of pediatric experiences poses a significant challenge to training programs. A national simulation curriculum can assist in providing a standardized foundation of pediatric training experience to all EM trainees. Previously, a consensus-derived set of content for a pediatric curriculum for EM was published. This study aimed to prioritize that content to establish a pediatric simulation-based curriculum for all EM residency programs. Methods: Seventy-three participants were recruited to participate in a three-round modified Delphi project from 10 stakeholder …