Digital Commons Network^™

Postinfectious Cerebellar Syndrome With Paraneoplastic Antibodies: An Association Or Coincidence?, Sajid Hameed, Mukesh Kumar, Pal Satyajit Singh Athwal, Sukhmanii Kahlon, Nimit Dalal

Section of Neurology

Cerebellar ataxia has a very broad differential diagnosis in adults, including paraneoplastic and postinfectious etiologies. We report a case of a 56-year-old male presented with right-sided cerebellar dysfunction preceded by fever and headache. He was diagnosed with subacute postinfectious cerebellar ataxia. Blood serology showed the presence of anti-amphiphysin and anti-Ri (ANNA-2, antineuronal nuclear autoantibody type 2) antibodies, which have a known association with cerebellar syndrome. The patient subsequently improved with the steroids. Although no evidence of an underlying tumor was found in the patient, the presence of the paraneoplastic antibodies remains a mystery. We suggest a probable association of these …

Molecular Characterization Of Plasmid-Mediated Non-O157 Verotoxigenic Escherichia Coli Isolated From Infants And Children With Diarrhea, Md Fazlul Karim Khan, Shah Samiur Rashid, Mohammad Nazmul, Hassan Maziz, Aizi Nor Mazila Ramli, Roesnita Baharuddin

Baghdad Science Journal

A significant increase in the incidence of non-O157 verotoxigenic Escherichia coli (VTEC) infections have become a serious health issues, and this situation is worsening due to the dissemination of plasmid mediated multidrug-resistant microorganisms worldwide. This study aims to investigate the presence of plasmid-mediated verotoxin gene in non-O157 E. coli. Standard microbiological techniques identified a total of 137 E. coli isolates. The plasmid was detected by Perfectprep Plasmid Mini preparation kit. These isolates were subjected to disk diffusion assay, and plasmid curing with ethidium bromide treatment. The plasmid containing isolates were subjected to a polymerase chain reaction (PCR) for investigating the …

Relationship Between Humidity And Physiology In Warm And Humid Conditions – A Literature Review, Yuliya Dzyuban

Research Collection School of Social Sciences

Change in precipitation patterns caused by global warming will likely increase humidity in some areas of the world. Moreover, populations in tropical climates with already high humidity levels can experience an added stress on their health and thermal comfort due to an amplifying effect of heat and moisture. Humidity is a generic term commonly used to describe moisture in the air. However, there are numerous variables that describe different properties of humid air that can be used in scientific studies. While relative humidity remains the most used, it has several shortcomings associated with its high correlation with air temperature. Thus, …

Relationship Between Humidity And Physiology In Warm And Humid Conditions: A Literature Review, Yuliya Dzyuban

Research Collection School of Social Sciences

Change in precipitation patterns caused by global warming will likely increase humidity in some areas of the world. Moreover, populations in tropical climates with already high humidity levels can experience an added stress on their health and thermal comfort due to an amplifying effect of heat and moisture. Humidity is a generic term commonly used to describe moisture in the air. However, there are numerous variables that describe different properties of humid air that can be used in scientific studies. While relative humidity remains the most used, it has several shortcomings associated with its high correlation with air temperature. Thus, …

Determinants Of Health Care Seeking Behaviors In Puerperal Sepsis In Rural Sindh, Pakistan: A Qualitative Study, Shabina Ariff, Fatima Mir, Farhana Tabassum, Farrukh Raza, Atif Habib, Ali Turab, Amnesty Lefevre, Linda A. Bartlett, Sajid Bashir Soofi, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

Background: Puerperal sepsis (PS) is one of the major causes of maternal death, contributing to 26,000 deaths per year in developing countries. Early recognition and treatment are essential to managing PS, but numerous social, cultural and technical barriers prevent or delay access to care and necessary medical attention. Through this qualitative study, we identified barriers to care seeking for puerperal sepsis among recently delivered women in Matiari, Pakistan.
Methods: We conducted 20 in-depth interviews among recently delivered women with and without sepsis and their family members in September 2012. Key informant interviews were conducted with 14 healthcare providers and traditional …

Sodium Butyrate Reduces Salmonella Enteritidis Infection Of Chicken Enterocytes And Expression Of Inflammatory Host Genes In Vitro, Anamika Gupta, Mohit Bansal, Basanta Raj Wagle, Xiaolun Sun, Narayan Rath, Annie Donoghue, Abhinav Upadhyay

Poultry Science Faculty Publications and Presentations

Salmonella Enteritidis (SE) is a facultative intracellular pathogen that colonizes the chicken gut leading to contamination of carcasses during processing. A reduction in intestinal colonization by SE could result in reduced carcass contamination thereby reducing the risk of illnesses in humans. Short chain fatty acids such as butyrate are microbial metabolites produced in the gut that exert various beneficial effects. However, its effect on SE colonization is not well known. The present study investigated the effect of sub-inhibitory concentrations (SICs) of sodium butyrate on the adhesion and invasion of SE in primary chicken enterocytes and chicken macrophages. In addition, the …

Covid-19, Lockdown, And The Dynamics Of Subjective Well-Being, Terence C. Cheng, Kim, Kanghyock Koh

Research Collection School Of Economics

We provide novel evidence on how the COVID-19 global health and economic crisis is affecting overall life satisfaction and domain-specific satisfaction using data from a monthly longitudinal survey of middle-aged and older Singaporeans. Using a difference-in-differences framework, we document large declines in overall life satisfaction and domain-specific satisfaction during the COVID-19 outbreak, except satisfaction with health. These declines coincide with the introduction of a nationwide lockdown, with life satisfaction remaining below its pre-pandemic levels even after the lockdown is lifted. We also find that individuals who report a drop in household income during the COVID-19 outbreak experience a decline in …

Spending Impact Of Covid-19 Stimulus Payments: Evidence From Card Transaction Data In South Korea, Kim, Kanghyock Koh, Wonjun Lyou

Research Collection School Of Economics

Various countries have implemented transfer programs to individuals since the Covid-19 outbreaks. However, the extent to which such transfers alleviate economic recessions is unclear. This paper analyzes a South Korean program, which provided vouchers redeemable only at small local businesses. We find that, due to the program, over 30% of households across all income groups increased their food and overall household spending, but the usage restriction may have affected consumer choice, distorting business competition. While the employment and sales of small businesses improved, the program’s fiscal sustainability is in question because of the large tax exemption.

The Ideals Of Law In A Health Crisis: Singapore’S Legislative Responses To Covid‐19, Benjamin Joshua Ong

Research Collection Yong Pung How School Of Law

Situations like the COVID-19 pandemic pose a dilemma. One might argue that such a crisis is a time for people to sacrifice their legal rights for the common good and submit to heavy restrictions on one’s liberties, surrendering individual liberties to a benevolent, though powerful, state. On the other hand, for every situation in history where an emergency has required people to accept such restrictions, there are many more situations in which an unscrupulous government has used a pretend emergency, or a real but exaggerated one, as an excuse to arrogate to himself sweeping arbitrary powers and refuse to let …

An Intersectional Mixed Methods Approach To Understand American Indian Men’S Health, Ka‘Imi Sinclair, Kelly L. Gonzales, Claire Woosley, Tish Rivera Cree, Celina M. Garza, Dedra Buchwald

OHSU-PSU School of Public Health Faculty Publications and Presentations

This study used a parallel, convergent, mixed-methods design with TribalCrit theory and intersectionality as analytical frameworks to identify how the identities of American Indian men intersect with broader structures and systems in shaping their eating and physical activity choices and behaviors, and in eliciting recommendations for a men’s lifestyle intervention. American Indian men were recruited in Minneapolis, Minnesota, and Portland, Oregon, between March and December 2017, and in Phoenix, Arizona, in December 2019 to participate in a survey and focus groups. The survey included questions on demographics and physical and cultural activities men engage in, perceived social support for lifestyle …

Redesigning The Landscape For Women And Leadership: Insights Gained From The Covid-19 Pandemic. On Behalf Of Women In Gastroenterology Network Asia Pacific (Wignap) And Women In Endoscopy (Wie), Lubna Kamani, Nonthalee Pausawasdi, Jeanin E Van Hooft, Amrita Sethi, Sharmila Sachithanandan

Section of Gastroenterology

No abstract provided.

Letter: Thrombotic Neurovascular Disease In Covid-19 Patients., Ahmad Sweid, Batoul Hammoud, Joshua H. Weinberg, Mazen Oneissi, Eytan Raz, Maksim Shapiro, Maureen Deprince, Stavropoula Tjoumakaris, Michael R. Gooch, Nabeel A. Herial, Hekmat Zarzour, Victor Romo, Robert Rosenwasswer, Pascal Jabbour

Department of Neurosurgery Faculty Papers

Although the respiratory system is the primary target of the coronavirus, studies have demonstrated a strong tropism to the central nervous system (CNS).^1,2 The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects cells by binding to the angiotensin-converting enzyme 2 (ACE2) receptor. This receptor is also found in the CNS and plays a crucial role in autoregulating cerebral perfusion pressure.^3,4 Additionally, epidemiological data demonstrated increased mortality due to cardiovascular and cerebrovascular diseases during flu pandemics due to a hypercoagulable state.^5,6 The triad of neuroinvasion of SARS-CoV-2, induction of hypercoagulable state,^{5-9 …}

Development Of A Semi-Quantitative Methodology For Evaluation Of Whole-Body Chemical, Biological, Radiological, And Nuclear Decontamination Using An Ultraviolet Fluorescent Aerosol, Emily M. Titus

Theses and Dissertations

This work describes a literature review which was conducted on publicly available literature on chemical, biological, radiological, and nuclear (CBRN) decontamination to understand the body of knowledge and gaps in this body of knowledge, including the assumption that disrobing after a CBRN incident will remove 90% of contamination. Also included is a description of the design and characterization of an aerosol test chamber which was constructed for use in this research. Finally, the bulk of this work describes the development of a semi-quantitative methodology for visualizing contamination. This method uses an ultraviolet fluorescent aerosol (to simulate contamination by a chemical …

Facilitating Access To A Covid-19 Vaccine Through Global Health Law, Lawrence O. Gostin, Safura Abdool Karim, Benjamin Mason Meier

Georgetown Law Faculty Publications and Other Works

This column explores the global health law reforms necessary to progressively realize universal access to a future COVID-19 vaccine. We begin by explaining the importance of global health law in the distribution of essential vaccines as a determinant of public health. The column then turns to examine the human rights foundations of global health law, conceptualizing vaccination access as a universal human right. We find that it will be crucial to develop legal commitments to ensure vaccine access prior to a scientific breakthrough, analyzing the legal barriers that impede global access and the global health law reforms necessary to facilitate …

Investigation Of Undocumented Heart Disease In Cadaveric Donors, Crystal Danae Passburg

Doctoral Dissertations and Projects

For nearly a century, heart disease has been the leading source of death and disease in the United States, causing the deaths of hundreds of thousands of individuals every year and burdening millions more with diminished health and severe disability. However, despite the significant known prevalence of heart disease, studies suggest that many more individuals—and particularly those within the female and elderly populations—may possess undiagnosed heart disease which remains undetected even after death due to the lack of autopsy examination. In the absence of autopsy, many cases of heart disease may never be identified, resulting in a skewed understanding of …

Understanding Characteristics Of The 100 Most Influential Studies On Covid-19 (Sars-Cov-2): A Bibliometric Analysis, Sidhartha Sahoo, Shriram Pandey, R. K. Mahapatra

Library Philosophy and Practice (e-journal)

Abstract

Background

In present study, we aimed to identify and evaluate the trends of the 100 most-cited research articles on Covid-19 using bibliometric techniques.

Methods

Scopus online database hosted by Elsevier was used to extract relevant articles for this study. We have identified the top 100 research papers on Covid-19 published across the globe based on their citations data. Further analysis was made to find the countries of origin, journal wise distribution, author cluster network, keyword analysis and inter-citation map to understand and to establish the links among them.

Results

The T100 most cited articles were published between January-August, 2020 …

Oxygen Targets In The Intensive Care Unit During Mechanical Ventilation For Acute Respiratory Distress Syndrome: A Rapid Review, Andrew F. Cumpstey, Alex H. Oldman, Andrew F. Smith, Daniel Martin, Michael P.W. Grocott

Peninsula Medical School

No abstract provided.

Imaging Features Of Neonatal Systemic Juvenile Xanthogranuloma: A Case Report And Review Of The Literature, Siping He, Ke Jin, Xicheng Deng, Zhengzhen Zhou, Robert C Mckinstry, Yong Wang

Open Access Publications

Juvenile xanthogranuloma (JXG) is the most common non-Langerhans cell histiocytic disorder in children. This report describes the case of a 28-day-old boy that presented with multiple subcutaneous nodular lesions on the trunk and extremities, and multiple red nodular lesions on the scrotum. Magnetic resonance imaging (MRI) of the brain showed a well-demarcated extra-axial dura-based mass that appeared isointense or slightly hyperintense on T1-weighted images, hypointense on T2-weighted images and had intense enhancement on gadolinium-enhanced T1-weighted images. Computed tomography (CT) or MRI scans of the chest and abdomen revealed multiple scattered nodular or patchy lesions of varying sizes in the lungs, …

Impact Of Annual And Semi-Annual Mass Drug Administration For Lymphatic Filariasis And Onchocerciasis On Hookworm Infection In Côte D'Ivoire, Agodio Loukouri, Aboulaye Méité, Benjamin G. Koudou, Charles W. Goss, Daphne Lew, Gary J. Weil, Eliezer K. N'Goran, Peter U. Fischer

Open Access Publications

Mass Drug Administration (MDA) programs to eliminate Lymphatic Filariasis (LF) in western Africa use the anthelminthics ivermectin plus albendazole. These drugs have the potential to impact also Soil-Transmitted Helminth (STH) infections, since the drugs have a broad range of anthelminthic activity. Integration of preventive chemotherapy efforts for LF, onchocerciasis and STH is recommended by the World Health Organization (WHO) in order to avoid duplication of MDA and to reduce costs. The objective of the current study was to determine whether five semi-annual rounds of community-wide MDA to eliminate LF and onchocerciasis have a greater impact on STH than three annual …

Covid-19: The Culprit, The People And Lessons Learned, Kayihura Manigaba, Mukundwa K. Gael

HCA Healthcare Journal of Medicine

COVID-19 has had a palpable impact on everyone from losing jobs to losing loved ones. It has altered our social dynamics and disturbed the world economy. We should all learn something from this challenging time. This article elaborates on three lessons learned by two brothers who grew up in Rwanda right after the 1994 genocide against the Tutsi, where more than one million people died in 100 days. One, Dr. Kayihura Manigaba, is currently responding to the COVID-19 pandemic as a clinical pharmacy manager and as an infectious diseases pharmacy specialist at a hospital in Florida, U.S, and the other, …

Risks Of Hiv/Aids Transmission: A Study On The Perceptions Of The Wives Of Migrant Workers Of Bangladesh, Humayun Kabir, Syadani R. Fatema, Saiful Hoque, Jesmin Ara, Myfanwy Maple

Journal of International Women's Studies

In recent years, an increasing number of Bangladeshi men have been working overseas. Whilst working abroad, some migrants engage in unprotected sexual activities, making them vulnerable to different kinds of sexually transmitted infections (STIs) including the Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS). Upon return home, the wives of these migrant workers are also highly susceptible to contracting HIV/AIDS. This study explores how and what the wives of the migrant workers perceive as practices of health safety regarding HIV/AIDS. In this connection, the Health Belief Model (HBM) was used as a theoretical lens for this study. Data were collected …

Enrichment Of Ontologies Using Machine Learning And Summarization, Hao Liu

Dissertations

Biomedical ontologies are structured knowledge systems in biomedicine. They play a major role in enabling precise communications in support of healthcare applications, e.g., Electronic Healthcare Records (EHR) systems. Biomedical ontologies are used in many different contexts to facilitate information and knowledge management. The most widely used clinical ontology is the SNOMED CT. Placing a new concept into its proper position in an ontology is a fundamental task in its lifecycle of curation and enrichment.

A large biomedical ontology, which typically consists of many tens of thousands of concepts and relationships, can be viewed as a complex network with concepts as …

Integrate Structural Analysis, Isoform Diversity, And Interferon-Inductive Propensity Of Ace2 To Predict Sars-Cov2 Susceptibility In Vertebrates, Eric R. Sang, Yun Tian, Yuanying Gong, Laura C. Miller, Yongming Sang

Agricultural and Environmental Sciences Faculty Research

The current new coronavirus disease (COVID-19) has caused globally over 0.4/6 million confirmed deaths/infected cases across more than 200 countries. As the etiological coronavirus (a.k.a. SARS-CoV2) may putatively have a bat origin, our understanding about its intermediate reservoir between bats and humans, especially its tropism in wild and domestic animals are mostly unknown. This constitutes major concerns in public health for the current pandemics and potential zoonosis. Previous reports using structural analysis of the viral spike protein (S) binding its cell receptor of angiotensin-converting enzyme 2 (ACE2), indicate a broad potential of SARS-CoV2 susceptibility in wild and particularly domestic animals. …

2020-08-31_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Second Round Of Urgent Covid-19 Research Launches, Selwyn M. Vickers Md

Browse All News

No abstract provided.

12 Honored For Excellence In Teaching, Haley Herfurth

Browse All News

No abstract provided.

Epigenetic Diet To Modulate Immune Response Against Sars-Cov-2, Andika Andika, Risa Ahdyani, Linda Erlina, Azminah Azminah, Arry Yanuar

Pharmaceutical Sciences and Research

The COVID-19 pandemic has spread to various parts of the world and caused many deaths. The victims are infected by SARS-CoV-2, a new type of coronavirus that has appeared since December 2019 and caused respiratory symptoms, fever, coughing, and shortness of breath. In addition to social distancing, wearing masks and washing hands, diet is important as a defense of the body against SARS-CoV-2. In this review, researchers conducted epigenetic diet studies that could potentially inhibit SARS-CoV-2, and can be consumed and used on a daily basis.

A Novel Mucosal Vaccine Platform For Immunization Against Plague, Christina D'Arco

NYMC Student Theses and Dissertations

Yersinia pestis, the causative agent of plague, has killed millions throughout human history. Today, it remains a significant threat for use as a bioweapon. Naturally occurring antibiotic resistance has been observed in Y. pestis isolates, and resistant strains have been engineered for use in biological warfare. Vaccines remain our best means of protection against plague, as well as countless other global contagions. We have developed a vaccine consisting of two Y. pestis virulence proteins, LcrV (V) and F1, conjugated to Tobacco Mosaic Virus (TMV), a safe, non-replicating plant virus that can be administered mucosally, providing complete protection against pneumonic plague, …

Analysis Of The Altmetric Top 100 Altmetric Attention Score Coronavirus Publications, Lambodara Parabhoi

Library Philosophy and Practice (e-journal)

The emergence of the Covid-19 pandemic has led to the publication of many scientific papers. The goal of the present research was to analyze these papers using the Altmetric Attention Score (AAS). Statistics for 100 publications with high AAS scores were selected and exported from the Dimension database on May 22^nd 2020. The major findings were that these publications were published in 34 different journals or preprint repositories. More than one-third of the total of 657, 350 social media posts were collected from the Twitter platform. The top contributing countries were China, followed by the USA. The paper “The …

Visions Of The Republic Symposium: Voting With The Virus: Ensuring Democracy Via Bypassing The Excuse Requirements In Absentee Voting, Russell Spivak

Fordham Law Review Online

One of the many difficulties posed by measures undertaken to curb the spread of the COVID-19 pandemic may be an inability to vote. Should this pandemic bleed into the fall, gathering at polling places, for example, would contravene guidelines prohibiting large gatherings particularly in crammed quarters. As such, jurisdictions must act immediately to broaden the use of absentee voting. Unfortunately, seventeen states, either via statute or constitutional provision, presently require an “excuse” to vote absentee. This could theoretically pose a problem insofar as fear of contracting the disease or spreading it to others may or may not qualify. This Article …