Digital Commons Network^™

Myosight-Semi-Automated Image Analysis Of Skeletal Muscle Cross Sections, Susan L Hamilton

Faculty, Staff and Students Publications

BACKGROUND: Manual analysis of cross-sectional area, fiber-type distribution, and total and centralized nuclei in skeletal muscle cross sections is tedious and time consuming, necessitating an accurate, automated method of analysis. While several excellent programs are available, our analyses of skeletal muscle disease models suggest the need for additional features and flexibility to adequately describe disease pathology. We introduce a new semi-automated analysis program, MyoSight, which is designed to facilitate image analysis of skeletal muscle cross sections and provide additional flexibility in the analyses.

RESULTS: We describe staining and imaging methods that generate high-quality images of immunofluorescent-labelled cross sections from mouse …

Ryanodine Receptor 1-Related Disorders: An Historical Perspective And Proposal For A Unified Nomenclature, Carsten G Bönnemann, James J Dowling, Susan L Hamilton, Katherine G Meilleur, Robert T Dirksen

Faculty, Staff and Students Publications

The RYR1 gene, which encodes the sarcoplasmic reticulum calcium release channel or type 1 ryanodine receptor (RyR1) of skeletal muscle, was sequenced in 1988 and RYR1 variations that impair calcium homeostasis and increase susceptibility to malignant hyperthermia were first identified in 1991. Since then, RYR1-related myopathies (RYR1-RM) have been described as rare, histopathologically and clinically heterogeneous, and slowly progressive neuromuscular disorders. RYR1 variants can lead to dysfunctional RyR1-mediated calcium release, malignant hyperthermia susceptibility, elevated oxidative stress, deleterious post-translational modifications, and decreased RyR1 expression. RYR1-RM-affected individuals can present with delayed motor milestones, contractures, scoliosis, ophthalmoplegia, and respiratory insufficiency.Historically, RYR1-RM-affected individuals were …

Anemocheck-Lrs: An Optimized, Color-Based Point-Of-Care Test To Identify Severe Anemia In Limited-Resource Settings, Marina S Perez-Plazola, Erika A Tyburski, Luke R Smart, Thad A Howard, Amanda Pfeiffer, Russell E Ware, Wilbur A Lam, Patrick T Mcgann

2020-Current year OA Pubs

BACKGROUND: Severe anemia is common and frequently fatal for hospitalized patients in limited-resource settings. Lack of access to low-cost, accurate, and rapid diagnosis of anemia impedes the delivery of life-saving care and appropriate use of the limited blood supply. The WHO Haemoglobin Colour Scale (HCS) is a simple low-cost test but frequently inaccurate. AnemoCheck-LRS (limited-resource settings) is a rapid, inexpensive, color-based point-of-care (POC) test optimized to diagnose severe anemia.

METHODS: Deidentified whole blood samples were diluted with plasma to create variable hemoglobin (Hb) concentrations, with most in the severe (≤ 7 g/dL) or profound (≤ 5 g/dL) anemia range. Each …

Impact Of Diabetes On The Gut And Salivary Iga Microbiomes, Sarah M Gunter, Goo Jun, David Aguilar, William B Perkison, Craig L Hanis, Herbert L Dupont

Faculty, Staff and Student Publications

Mucosal surfaces like those present in the lung, gut, and mouth interface with distinct external environments. These mucosal gateways are not only portals of entry for potential pathogens but also homes to microbial communities that impact host health. Secretory immunoglobulin A (SIgA) is the single most abundant acquired immune component secreted onto mucosal surfaces and, via the process of immune exclusion, shapes the architecture of these microbiomes. Not all microorganisms at mucosal surfaces are targeted by SIgA; therefore, a better understanding of the SIgA-coated fraction may identify the microbial constituents that stimulate host immune responses in the context of health …

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

The George-Anne A.M., Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

#Golead Newsletter, Georgia Southern University

#GoLead Newsletter (2016-2023)

• OLCE Announcements
• Become a Service-Learning Facilitator by taking LEAD 3000!
• Serve
• Virtual Service
• On-Campus Service
• Off-Campus Service
• Additional Resources

Five Things You Should Know This Week, Georgia Southern University

A Few Things You Should Know This Week (2020-2023)

• Remain vigilant with public health guidelines
• The Legal Affairs Boot Camp has gone virtual!
• This is the final week for the Inclusive Excellence Campus Climate Survey
• Our virtual Homecoming was a success!
• Commencement is around the corner.

Newsroom, Georgia Southern University

Newsroom (2006-2023)

• Georgia Southern releases Economic Monitors Q2 and Q3, show signs of recovery in Savannah

• Langdon named international scholar by Center for Self- Determination Theory

2020-11-16 Message From The President, Morehead State University. Office Of The President.

Staff Congress Records

A message update from the Office of the President sent to students on November 16, 2020 regarding the completion of in-person classes on November 20 and remaining classes to be conducted virtually.

Student Life E-Newsletter November 16, 2020, Seattle University School Of Law Student Life

Student Life E-Newsletters

No abstract provided.

Wait., Kayla Cantu

Theses

Wait explores concepts of discomfort and acceptance through the use of the human body, glass, and honey. The artwork and this thesis both use personal experience of physical insecurities and scholarly investigations into psychology related to unruly bodies. The work and research allude to the material qualities of glass such as its malleability, susceptibility, and softness to draw a parallel between the materials and the human identity. Parallels between glass and body create conversations investigating acceptance of identity and questions ideas about resistance of unruly bodies.

Substance Use And Life-Course Narratives For Criminally Involved Veterans, Tyler J. Marcheschi

Theses and Dissertations

Criminal justice involvement stemming from substance use is a common issue with whichmilitary veterans struggle. Research on substance use has indicated that a multitude of negative life-course outcomes can result for individuals who abuse substances. While prior research has studied the relationships between substance use and military veterans, there is little empirical analysis that focuses on the narrative accounts of veterans and their experiences with substance use. The goal of the current thesis is to expand on this topic by exploring how criminally involved veterans experience substance use and the perceived impact substance use has on the life-course according to …

Information Seeking Patterns Of Small Scale Farmers For Farming Activities In Katsina State, Nigeria, Lawal Mohammed Tukur

Library Philosophy and Practice (e-journal)

Abstract

This study identified Small Scale Farmers (SSF) information seeking patterns used and types of crops produced for effective farming activities. Three research questions and one hypothesis were developed to guide the study. Cross sectional survey design was adopted in which a total of seven hundred (700) registered small scale farmers’ cooperative associations from three agricultural zones of Katsina state formed the population. A total number of two hundred and eighty (280) respondents were randomly sampled using cluster sampling technique. Data were analyzed using descriptive and inferential statistics in which the null hypothesis was tested using Pearson Product Moment Correlation …

20201116_New Website Tour, Kelleen Maluski

HSLIC Blog Post

No abstract provided.

Keep Moving And Stay Connected: Tips For Taking Care Of Older Loved Ones During A Pandemic, Adam Pope

Browse All News

No abstract provided.

Center Director At Uab To Lead International Organization Dedicated To Standardized Patient Education, Staff

Browse All News

No abstract provided.

Effect Of Varietal Resistance On The Yield Loss Function Of Wheat To Nodorum Blotch, Manisha Shankar, Karyn Reeves, Jason Bradley, Ryan Varischetti, Robert Loughman

Grain and Other Field Crops Research Articles

Cultivar disease resistance ratings to nodorum blotch (caused by Parastagonospora nodorum) provide critical information to growers to assist with disease management. However, less has been done in terms of yield losses from diseases under different cultivar resistance scenarios. The purpose of this study was to characterize yield and quality loss responses to wheat nodorum blotch as influenced by variety partial resistance, epidemic intensity, and environment. The trial series includes four site/years in Western Australia. Five varieties, Magenta, Calingiri, Trojan, Janz, and Scout were used for all four trials. These varieties represented resistant/susceptible categories MRMS, MS, MSS, S, and SVS, …

Any Publicity Is Good Publicity: Positive, Negative And Neutral Tweets Can All Become Trends, Ma Palomino, Varma A Padmanabhan

School of Engineering, Computing and Mathematics

No abstract provided.

Spirit-Empowered Leadership: Exploring Three Dimensions, Jay Gary

Spiritus: ORU Journal of Theology

How should colleges and universities within the Spirit-empowered Movement develop Spirit-empowered leadership among their students, staff, or faculty? To spur on thinking by those who frame university learning outcomes, this case study from Oral Roberts University defines Spirit-empowered leadership in terms of three dimensions: personal development, interpersonal influence, and generational emergence. It concludes with a call to create the frameworks of leadership needed for the future of the church and society, in light of A.D. 2033, the 2,000th anniversary of Pentecost.

In Memoriam : Vinson Synan: Model Of Spirit-Led Leadership, Sally Jo Shelton

Spiritus: ORU Journal of Theology

H. Vinson Synan (December 1, 1934—March 15, 2020) was a key successor to David du Plessis, known as Mr. Pentecost, to Catholic and mainline Protestant leaders. Like du Plessis, Synan was a classical Pentecostal who dedicated much of his life to promoting the move of the Holy Spirit beyond the confines of his own classical Pentecostal denomination, the International Pentecostal Holiness Church. His call to this work came in 1972 at an annual Catholic Charismatic Conference held at Notre Dame University when seeing some 8,000participants singing in the Spirit, he came to the conviction that Catholics had indeed received the …

Full Issue - Spiritus 5, Vol 2 (2020), Spiritus Journal

Spiritus: ORU Journal of Theology

This special journal issue devoted to Spirit-empowered leadership.

John Thompson, guest editor.

Insights From Pennsylvania: Marketing Agritourism For The American Cider Culture, Alison E. Feeney, Antonia Price, Rachel Idacavage

Journal of Tourism Insights

Destinations and activities for travelers are greatly influenced by official tourism agencies that promote their local resources. Marketing for well-known places like breweries or vineyards can be straight forward, but destinations without clear descriptions can be more challenging. This paper examined how cider is defined, promoted, and marketed by official tourism websites to evaluate its potential for supporting the agritourism industry given the resurgence in craft beverages and increased public interest to purchase local products. Discrepancies between federal and state regulations of cider contribute to the public’s lack of awareness of what cider is, who can make it, and how …

Thriving Private-Community Partnerships: Perspectives From Fiji’S Upper Navua Conservation Area, Jeremy Schultz, Kelly Bricker

Journal of Tourism Insights

Ecotourism has proven itself to be a forerunner in the advancement of environmental conservation all the while supporting cultural tradition, uniqueness, and pride among indigenous communities. Successful private-community partnerships associated with ecotourism operations are vital to the overall prosperity of both the businesses and the local communities. Such accomplishments can be seen through numerous livelihood goals including income, food security, health, reduced vulnerability, governance, and empowerment (Walpole & Wilder, 2008).

Private-community partnerships also support global initiatives such as the Sustainable Development Goals (Ban Ki-Moon, 2015) and sustainable development frameworks including those proposed by the United Nations World Tourism Organization (UNWTO, …

Understanding Contraflow Pop-Culture Tourism: The Case Of Transnational Fandom Of South Korean Pop-Culture And The “Hallyu” Tourism, Jungyun "Christine" Hur, Tony Kim

Journal of Tourism Insights

Pop-culture tourism has continuously grown its market among those who are fanatic of pop-culture, and destination marketers have noticed pop-culture as an effective marketing tool to attract more visitors. Pop-culture has been dominant by the US, but interestingly, a recent phenomenon sees a contra-cultural flow. This paper explores contraflow pop-culture tourism and guides the reader to how to understand this new tourism niche. Reviewing the case of transnational fandom of South Korean pop-culture, so called “Korean Wave” or “Hallyu” and its impact on inbound tourism, this paper suggests digital mediation as a key driver of contraflow pop-culture and transnational fandom, …

Travel Motives And Golf Tourists: An Exploratory Study, Chris Brown, Yuri Feito

Journal of Tourism Insights

Over the past 25 years the concept of sport tourism has taken on numerous forms and broadened tourism and sport research tremendously. Hui, Wan, and Ho (2007) indicated that the global tourism industry has become increasingly competitive, and golf tourism, as a subcategory of sport tourism, has received more recent attention within the tourism industry. Thus, it is becoming more important for golf courses and golf destinations to identify the variables which attract and retain their golfing clientele. The identification of common characteristics and travel motivations among golf tourists could provide useful information to golf destination marketers in targeting their …

Volume 7, 2020

James Madison Undergraduate Research Journal (JMURJ)

No abstract provided.

Availability And Utilization Of E-Resources In University Libraries For Effective Research Output By Undergraduates Of Social Studies In South East Nigeria, Joseph C. Onuoha Ph.D, , Lilian Ujunwa Ifeanyi, Abdulrahman Yakubu Yunisa

Library Philosophy and Practice (e-journal)

This study sought to investigate the availability and utilization of e-resources in university libraries for effective research output by undergraduates of Social Studies in south-east, Nigeria. It is a descriptive survey research design. two research questions guided the study. A sample of 191 students from four stratified randomly selected universities in south east, Nigeria, were used for the study. The instrument for data collection is the researcher’s designed and validated questionnaire, tagged: ‘The Use of E-Resources in University Libraries Questionnaire’ (UERULQ). The instrument was trial tested using Cronbach Alpha, while reliability coefficient of 0.98 was obtained, which was considered high …

The Soil Organic Carbon Spatial Distribution Of Degraded Grassland With Black Soil Type In The Source Region Of Yellow River, Duofeng Pan, Y. S. Ma, Y. X. Zhang

IGC Proceedings (1977-2023)

No abstract provided.

Potential Of Hemp (Cannabis Sativa L.) For Paired Phytoremediation And Bioenergy Production, Hanah T. Rheay, Emmanuel C. Omondi, Catherine E. Brewer

Agricultural and Environmental Sciences Faculty Research

Hemp (Cannabis sativa L.) is a multi-use crop that has been investigated for its potential use in phytoremediation of heavy metals, radionuclides, and organic contaminants, and as a feedstock for bioenergy production. A review of research literature indicates that hemp is a suitable crop for phytoremediation, and a competitive option for bioenergy. Coupling phytoremediation and bioenergy production from a single hemp crop is a potential solution to overcoming the economic constraints of phytoremediation projects. The current challenge is ensuring that the extracted contaminants are not introduced into the consumer marketplace. After several decades of limited research on hemp in the …