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2020

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A Perspective On Our Most Valuable Natural Resource, Brenda Thompson Aug 2020

A Perspective On Our Most Valuable Natural Resource, Brenda Thompson

UCF Forum

What are America’s most valuable natural resources and where can they be found? These questions are as important today as they have ever been.


Alcohol Affects The Reward Pathway Of The Brain Via A6-Containing Nicotinic Acetylcholine Receptors In The Nucleus Accumbens, Elizabeth Qiufeng Anderson Aug 2020

Alcohol Affects The Reward Pathway Of The Brain Via A6-Containing Nicotinic Acetylcholine Receptors In The Nucleus Accumbens, Elizabeth Qiufeng Anderson

Theses and Dissertations

The prevailing view is that enhancement of dopamine (DA) transmission in the mesolimbic system consisting of DA neurons in the ventral tegmental area (VTA) that project to the nucleus accumbens (NAc) underlies the rewarding properties of ethanol (EtOH) and nicotine (NIC). Although the dogma is that EtOH enhancement of DA neural activity contributes to enhancement of DA transmission, DA neurons are not sensitive to rewarding levels of EtOH. However, VTA GABA neurons are sensitive to low-dose EtOH. We have shown previously that EtOH modulation of DA release in the NAc is mediated by α6-containing nicotinic receptors (α6*-nAChRs), that α6*-nAChRs mediate …


Osterix-Cre Marks Distinct Subsets Of Cd45- And Cd45+ Stromal Populations In Extra-Skeletal Tumors With Pro-Tumorigenic Characteristics, Biancamaria Ricci, Eric Tycksen, Hamza Celik, Jad I. Belle, Francesca Fontana, Roberto Civitelli, Roberta Faccio Aug 2020

Osterix-Cre Marks Distinct Subsets Of Cd45- And Cd45+ Stromal Populations In Extra-Skeletal Tumors With Pro-Tumorigenic Characteristics, Biancamaria Ricci, Eric Tycksen, Hamza Celik, Jad I. Belle, Francesca Fontana, Roberto Civitelli, Roberta Faccio

Open Access Publications

Cancer-associated fibroblasts (CAFs) are a heterogeneous population of mesenchymal cells supporting tumor progression, whose origin remains to be fully elucidated. Osterix (Osx) is a marker of osteogenic differentiation, expressed in skeletal progenitor stem cells and bone-forming osteoblasts. We report


The Flower Paintings Of Albert York, Scott Seaboldt Aug 2020

The Flower Paintings Of Albert York, Scott Seaboldt

Theses and Dissertations

Albert York (American, 1928–2009) is said to have created approximately 250 paintings. Along with a biographical study, a selective analysis of the over 90 flower paintings is conducted through historical, comparative, and analytical investigations. The floral works are definitive touchstones of York's artistic growth and remain rich with symbolic content.


Painting Politics: The Anarchist Art And Lives Of Camille Pissarro And Barnett Newman, Johan Marby Aug 2020

Painting Politics: The Anarchist Art And Lives Of Camille Pissarro And Barnett Newman, Johan Marby

Theses and Dissertations

The times in and around the Paris Commune and the Depression followed by Second World War in the United States were instances in history that greatly influenced artists’ output. This thesis investigates how anarchist thought and activities during these periods, respectively, affected the œuvres of Camille Pissarro and Barnett Newman.


Daphne Odjig: Indigenous Art And Contemporary Curatorial Practices, Lucy Kay Riley Aug 2020

Daphne Odjig: Indigenous Art And Contemporary Curatorial Practices, Lucy Kay Riley

Theses and Dissertations

This thesis examines the history of curatorial practices and scholarship regarding the work and life of Daphne Odjig (1919-2016), a self-taught Canadian artist of Potawatomi and English ancestry, in order to situate her at the crux of the contemporary Indigenous art movement in Canada.


St. Luke's Health System V. Board Of Commissioners Appellant's Brief Dckt. 47872 Aug 2020

St. Luke's Health System V. Board Of Commissioners Appellant's Brief Dckt. 47872

Idaho Supreme Court Records & Briefs, All

No abstract provided.


Hotline Press Newspaper- August 2020 Vol 36 No 19, Hotline Press Newspaper Aug 2020

Hotline Press Newspaper- August 2020 Vol 36 No 19, Hotline Press Newspaper

Hotline Press Newspaper 2020

No abstract provided.


Karl G. Maeser: The Mormon Pestalozzian, Renae Myers Aug 2020

Karl G. Maeser: The Mormon Pestalozzian, Renae Myers

Undergraduate Honors Theses

Karl G. Maeser, the founder of Brigham Young Academy (now Brigham Young University), was able to bring progressive education to a pioneer society largely due to his educational and spiritual preparation. He was trained in the pedagogical methods of Johann Heinrich Pestalozzi who believed that children learned best inductively, mainly through observation. Pestalozzi also believed that children were worthy of love and respect. Maeser was able to emulate Pestalozzi’s methods in an unprecedented way not only because the doctrine of The Church of Jesus Christ aligned so well with Pestalozzi’s methods, but because Maeser strove to have the Spirit of …


Algal Coverage Detection And Classification Using Envi: Correlation With Dissolved Oxygen Levels In Elkhorn Slough, Ca, Jason Dawson Aug 2020

Algal Coverage Detection And Classification Using Envi: Correlation With Dissolved Oxygen Levels In Elkhorn Slough, Ca, Jason Dawson

All HCAS Student Capstones, Theses, and Dissertations

Estuaries are exposed to varying stressors, whether they be physical, chemical, or environmental. The most notable of stressors is eutrophication of coastal and inland ecosystems. This is a result of increased supply of nutrients fueling production within the system. One outcome of this increased nutrient load to the system is that of algal blooms. These blooms can impact the aesthetic appearance and degrade the quality of health of the system. Many of these coastal zones and waterways are critical habitats for many biological (some endangered) species and serve as recreational areas for human populations. Elkhorn Slough, California is one of …


Linking Crude Oil And Dispersant Effects To Gene Expression Of Marine Sponge Cinachyrella, Yvain Desplat Aug 2020

Linking Crude Oil And Dispersant Effects To Gene Expression Of Marine Sponge Cinachyrella, Yvain Desplat

All HCAS Student Capstones, Theses, and Dissertations

Because of their filter-feeding lifestyle, sponges (Phylum Porifera) have shown to be bio-accumulators of heavy metals, and bio-monitors for polychlorobiphenyl (PCB) contaminants. Furthermore, marine sponges have been shown to be regulators of reef ecosystems by fulfilling many ecological functions. However, very little is known about their behavior in the face of environmental changes. Consequently, our lab has developed the reef sponge Cinachyrella spp. as novel experimental model. We have designed an experiment to study the effects of WAF (Water Accommodated Fraction), Corexit 9500 dispersant, and CE-WAF (Chemically Enhanced Water Accommodated Fraction)mixtures, in an effort to mimic the conditions of the …


Dairy Milk And Plant-Based Alternative Beverage Purchasing Factors: Consumer Insights, Jeffrey Alan Rime Aug 2020

Dairy Milk And Plant-Based Alternative Beverage Purchasing Factors: Consumer Insights, Jeffrey Alan Rime

Theses and Dissertations

From 2000 to 2019, total volume of fluid milk consumption in the USA has steadily fallen. Many factors have played a role in this trend, including competition with plant-based alternative beverages (PBABs). Comparably, sales of PBABs such as almond “milk” have increased over the same duration. Consumer research has identified key beverage characteristics as purchase drivers for both beverage types. This study sought to evaluate the relative importance of these characteristics, investigate the effect of label statements on ratings of their acceptability, and analyze the settings in which and occasions during which consumption of dairy milk and PBABs occurs. This …


Considerations For Studying Sex As A Biological Variable In Spinal Cord Injury, Andrew N. Stewart, Steven M. Maclean, Arnold J. Stromberg, Jessica P. Whelan, William M. Bailey, John C. Gensel, Melinda E. Wilson Aug 2020

Considerations For Studying Sex As A Biological Variable In Spinal Cord Injury, Andrew N. Stewart, Steven M. Maclean, Arnold J. Stromberg, Jessica P. Whelan, William M. Bailey, John C. Gensel, Melinda E. Wilson

Physiology Faculty Publications

In response to NIH initiatives to investigate sex as a biological variable in preclinical animal studies, researchers have increased their focus on male and female differences in neurotrauma. Inclusion of both sexes when modeling neurotrauma is leading to the identification of novel areas for therapeutic and scientific exploitation. Here, we review the organizational and activational effects of sex hormones on recovery from injury and how these changes impact the long-term health of spinal cord injury (SCI) patients. When determining how sex affects SCI it remains imperative to expand outcomes beyond locomotor recovery and consider other complications plaguing the quality of …


Dha Modulates Manf And Trem2 Abundance, Enhances Neurogenesis, Reduces Infarct Size, And Improves Neurological Function After Experimental Ischemic Stroke, Ludmila Belayev, Sung Ha Hong, Raul S. Freitas, Hemant Menghani, Shawn J. Marcell, Larissa Khoutorova, Pranab K. Mukherjee, Madigan M. Reid, Reinaldo B. Oria, Nicolas G. Bazan Aug 2020

Dha Modulates Manf And Trem2 Abundance, Enhances Neurogenesis, Reduces Infarct Size, And Improves Neurological Function After Experimental Ischemic Stroke, Ludmila Belayev, Sung Ha Hong, Raul S. Freitas, Hemant Menghani, Shawn J. Marcell, Larissa Khoutorova, Pranab K. Mukherjee, Madigan M. Reid, Reinaldo B. Oria, Nicolas G. Bazan

School of Medicine Faculty Publications

Aims: Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a secretory neurotrophic factor protein that promotes repair after neuronal injury. The microglia cell surface receptor (triggering receptor expressed on myeloid cells-2; TREM2) regulates the production of pro- and antiinflammatory mediators after stroke. Here, we study MANF and TREM2 expression after middle cerebral artery occlusion (MCAo) and explore if docosahexaenoic acid (DHA) treatment exerts a potentiating effect. Methods: We used 2 hours of the MCAo model in rats and intravenously administered DHA or vehicle at 3 hours after the onset of MCAo. Neurobehavioral assessment was performed on days 1, 3, 7, and 14; …


Prediction Of Asiatic Acid Derivatives Affinity Against Sars-Cov-2 Main Protease Using Molecular Docking, Ida Musfiroh, Alia Resti Azura, Driyanti Rahayu Aug 2020

Prediction Of Asiatic Acid Derivatives Affinity Against Sars-Cov-2 Main Protease Using Molecular Docking, Ida Musfiroh, Alia Resti Azura, Driyanti Rahayu

Pharmaceutical Sciences and Research

COVID-19 is a pandemic that currently occurs in almost all parts of the world, caused by a new coronavirus species that can infect humans, namely SARS-CoV-2. To date, there is no effective drug to treat COVID-19. There are studies proving that the secondary metabolites of pentacyclic triterpenes have antiviral activity, one of which is asiatic acid. The aims of this study are to obtain the affinity and interactions of asiatic acid derivative structures in inhibiting the main protease of SARS-CoV-2. The research method was molecular docking of asiatic acid and its derivatives against the main protease of SARS-CoV-2 (6LU7) consisting …


Construct-Specific And Timing-Specific Aspects Of The Home Environment For Children’S School Readiness, Yemimah A. King, Robert Duncan, German Posada, David J. Purpura Aug 2020

Construct-Specific And Timing-Specific Aspects Of The Home Environment For Children’S School Readiness, Yemimah A. King, Robert Duncan, German Posada, David J. Purpura

Purdue Center for Early Learning Faculty and Staff Publications

Prior evidence supports that the home environment is related to children’s development of school readiness skills. However, it remains unclear how construct- and timing-specific aspects of the home environment are related to children’s school readiness skills, unique from overall, stable aspects of home quality. Unpacking associations due to specific constructs and timing of the home environment may provide insights on the theoretical processes that connect the home environment to school readiness. Using data from the NICHD Study of Early Child Care and Youth Development (N = 1,364), the current study examines how timing (36 and 54 months) and constructs …


The Effect Of The Missouri Preschool Program On School Readiness, Madeline June Allin Aug 2020

The Effect Of The Missouri Preschool Program On School Readiness, Madeline June Allin

Dissertations

National policymakers, practitioners, and researchers have consistently questioned how to develop the necessary skills for the nation’s youth to meet the challenges of the 21st century. The answer points directly to the provision of highquality early childhood programs to prepare children for entrance to kindergarten and put them on a trajectory toward lifelong positive outcomes (Ferrarello, 2017; Phillips et al., 2017). The Missouri Preschool Program is a high-quality, state grant-funded program, with grant priority given to schools serving a large number of disadvantaged children (MODESE, 2018a). The purpose of this quantitative causal-comparative study was to compare the school readiness skills …


Cytokine Storm In Covid-19: An Overview, Mechanism, Treatment Strategies, And Stem Cell Therapy Perspective, Nuriza Ulul Azmi, Meidi Utami Puteri, Donny Lukmanto Aug 2020

Cytokine Storm In Covid-19: An Overview, Mechanism, Treatment Strategies, And Stem Cell Therapy Perspective, Nuriza Ulul Azmi, Meidi Utami Puteri, Donny Lukmanto

Pharmaceutical Sciences and Research

Coronavirus disease 2019 (COVID-19) is the disease caused by the highly transmittable novel coronavirus (SARS-CoV-2) infections. The disease was found at the end of December 2019, in Wuhan, China, and quickly spread worldwide with a higher mortality rate compared to the previous coronavirus disease. Cytokine plays an important role in the inflammatory response against coronavirus infection. However, in severely ill patients with COVID-19, an excessive amount of cytokine serum level (cytokine storm) has been associated with the aggravation of coronavirus disease leading to acute respiratory distress syndrome (ARDS). Thus, the management of the cytokine storm could be the key to …


The Potential Roles Of Jamu For Covid-19: A Learn From The Traditional Chinese Medicine, Dwi Hartanti, Binar Asrining Dhiani, Shintia Lintang Charisma, Retno Wahyuningrum Aug 2020

The Potential Roles Of Jamu For Covid-19: A Learn From The Traditional Chinese Medicine, Dwi Hartanti, Binar Asrining Dhiani, Shintia Lintang Charisma, Retno Wahyuningrum

Pharmaceutical Sciences and Research

As the pandemic of the coronavirus disease 2019 (COVID-19) continues while there is no drug and vaccine available, every effort to discover one should be considered. This review aimed to discuss the potential use of jamu, the Indonesian traditional herbal medicine, to deal with COVID-19 by following those of more-established traditional Chinese medicine (TCM). The online literature search using the PubMed database, as well as the circulars from the Indonesian Ministry of Health, were carried out to collect data up to June 07, 2020. The use of TCM for the treatment and prevention of COVID-19 has been officiated in the …


Sars-Cov-2: Virology And Drug Repurposing Approaches, Ratika Rahmasari, Heri Setiawan, Rezi Riadhi Syahdi, Ayun Arifianti, Marina Ika Irianti, Rani Sauriasari, Juliann Nzembi Makau, Muhareva Raekiansyah Aug 2020

Sars-Cov-2: Virology And Drug Repurposing Approaches, Ratika Rahmasari, Heri Setiawan, Rezi Riadhi Syahdi, Ayun Arifianti, Marina Ika Irianti, Rani Sauriasari, Juliann Nzembi Makau, Muhareva Raekiansyah

Pharmaceutical Sciences and Research

An emerging coronavirus, SARS-CoV-2, is the causative agent for the ongoing pandemic of coronavirus disease 2019 (COVID-19), which has caused a worldwide social and economic disruption. Currently, no antiviral drugs with proven clinical efficacy, or vaccines for its prevention. Therefore, to combat the pandemic of this novel coronavirus, new effective treatments are urgently needed. In the process of traditional drug development, developing new drugs from scratch is a time- consuming process, requires high-investment, and is a high-risk process, which is impractical to face the immediate global challenge of the SARS-CoV-2 pandemic. Drug repurposing strategy is one of the effective ways …


Remdesivir: Mechanism And Effectiveness For Coronavirus Disease 2019 (Covid-19), Vina Neldi, Suharjono Suharjono Aug 2020

Remdesivir: Mechanism And Effectiveness For Coronavirus Disease 2019 (Covid-19), Vina Neldi, Suharjono Suharjono

Pharmaceutical Sciences and Research

Currently, coronavirus disease 2019 (COVID-19) is a very serious health problem. The World Health Organization (WHO) has characterized this disease as a pandemic. Recommendations related to vaccines and drugs are not available yet because they are still in the clinical trial phase, and one of the superior drugs is remdesivir which has an antiviral activity. Several clinical trials of this drug are being carried out with the aim of evaluating its safety and efficacy in COVID-19 patients. There are two clinical trials with completed recruitment status, which are NCT04257656 and NCT04280705. NCT04257656 showed that remdesivir had faster time for clinical …


Chloroquine: An Old To Be Repurposed Drug For Covid-19 Infection (Risk And Benefit), Oki Nugraha Putra, Ana Khusnul Faizah, Nani Wijayanti Dyah Nurrahman, Hardiyono Hardiyono Aug 2020

Chloroquine: An Old To Be Repurposed Drug For Covid-19 Infection (Risk And Benefit), Oki Nugraha Putra, Ana Khusnul Faizah, Nani Wijayanti Dyah Nurrahman, Hardiyono Hardiyono

Pharmaceutical Sciences and Research

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes Coronavirus Disease 2019 (COVID-19) with a high rate of mortality. Chloroquine and hydroxychloroquine have been used for antimalarial and autoimmune diseases for many years. Due to low toxicity and well tolerability as well as immunomodulatory properties, these drugs are proposed to treat viral infection. Some studies, both in vitro and in a clinical setting, have been evaluated for their ability to treat SARS- CoV-2 as promising therapies. Although The National Agency of Drugs and Food Control of The Republic of Indonesia issued emergency authorization for chloroquine and hydroxychloroquine to be used against …


Herbivores At The Highest Risk Of Extinction Among Mammals, Birds, And Reptiles, Trisha B. Atwood, Shaley A. Valentine, Edd Hammill, Douglas J. Mccauley, Elizabeth M. P. Madin, Karen H. Beard, William D. Pearse Aug 2020

Herbivores At The Highest Risk Of Extinction Among Mammals, Birds, And Reptiles, Trisha B. Atwood, Shaley A. Valentine, Edd Hammill, Douglas J. Mccauley, Elizabeth M. P. Madin, Karen H. Beard, William D. Pearse

Ecology Center Publications

As a result of their extensive home ranges and slow population growth rates, predators have often been perceived to suffer higher risks of extinction than other trophic groups. Our study challenges this extinction-risk paradigm by quantitatively comparing patterns of extinction risk across different trophic groups of mammals, birds, and reptiles. We found that trophic level and body size were significant factors that influenced extinction risk in all taxa. At multiple spatial and temporal scales, herbivores, especially herbivorous reptiles and large-bodied herbivores, consistently have the highest proportions of threatened species. This observed elevated extinction risk for herbivores is ecologically consequential, given …


Brainwaves And Intentions: The Readiness Potential And Its Relation To Free Will, Joanna Pak, Aaron Schurger, Adina Roskies, Pengbo Hu Aug 2020

Brainwaves And Intentions: The Readiness Potential And Its Relation To Free Will, Joanna Pak, Aaron Schurger, Adina Roskies, Pengbo Hu

SURF Posters and Papers

First discovered in 1965 by Kornhuber and Deecke, the readiness potential (RP) is a distinctive buildup of neural activity in motor areas of the brain that begins ~500 ms before voluntary movements. In 1983, Libet used the RP as the foundation for his argument against the existence of conscious free will. This argument became known as the classic model of the RP, which interprets the RP as a precursor to the conscious experience of volition and a quantifiable representation of unconscious brain activity preceding spontaneous movements. Although the classic model connected the RP to free will, the significance of the …


Covariates And Spatial Interpolation Of Hiv Screening In Mozambique: Insight From The 2015 Aids Indicator Survey, Pascal Agbadi, Jerry John Nutor, Ernest Darkwah, Henry Ofori Duah, Precious Adade Duodu, Robert Kaba Alhassan, Kimberly Baltzell Aug 2020

Covariates And Spatial Interpolation Of Hiv Screening In Mozambique: Insight From The 2015 Aids Indicator Survey, Pascal Agbadi, Jerry John Nutor, Ernest Darkwah, Henry Ofori Duah, Precious Adade Duodu, Robert Kaba Alhassan, Kimberly Baltzell

College of Nursing Faculty Research and Publications

We examined the factors associated with human immunodeficiency virus (HIV) screening and developed a HIV screening prevalence surface map using spatial interpolation techniques to identify the geographical areas with the highest and lowest rates of HIV screening in Mozambique. We analyzed the cross-sectional 2015 Mozambique AIDS Indicator Surveys with an analytic sample of 12,995 participants. Analyses were conducted on SPSS-21, STATA-14, and R freeware 3.5.3. We adjusted for the sample design and population weights. Results indicated that 52.5% of Mozambicans had undergone HIV screening. Mozambicans with these characteristics have a higher probability of undergoing HIV screening: females, those with a …


A Shark Conservationists Toolbox: Current Dna Methods And Techniques Aiding In The Conservation Of Sharks, Arianna N. Nixon Aug 2020

A Shark Conservationists Toolbox: Current Dna Methods And Techniques Aiding In The Conservation Of Sharks, Arianna N. Nixon

All HCAS Student Capstones, Theses, and Dissertations

Elasmobranchs are important members of their community. Many sharks are important apex predators that help maintain the health of their ecosystem. However, shark populations are globally declining. This is partially due to the fact that sharks are highly targeted for their fins, meat, liver oil, teeth, and skin. However, they are also killed from anthropogenic effects such as habitat destruction and pollution. Most shark species have life history characteristics that also make them more vulnerable to overfishing. Sharks are also difficult to study due to their elusive nature and identification issues. That is why molecular tools are increasingly becoming important …


Enantiomerically Pure Quinoline-Based Κ-Opioid Receptor Agonists: Chemoenzymatic Synthesis And Pharmacological Evaluation, Benedikt Martin, Dirk Schepmann, Freddy A Bernal, Thomas J Schmidt, Tao Che, Karin Loser, Bernhard Wünsch Aug 2020

Enantiomerically Pure Quinoline-Based Κ-Opioid Receptor Agonists: Chemoenzymatic Synthesis And Pharmacological Evaluation, Benedikt Martin, Dirk Schepmann, Freddy A Bernal, Thomas J Schmidt, Tao Che, Karin Loser, Bernhard Wünsch

2020-Current year OA Pubs

Racemic


Effects Of Liming And Nitrogen Application On The Cu, Mn, And Zn Concentrations In Herbage From Extensively Managed Pastures, Harald Laser Aug 2020

Effects Of Liming And Nitrogen Application On The Cu, Mn, And Zn Concentrations In Herbage From Extensively Managed Pastures, Harald Laser

IGC Proceedings (1977-2023)

No abstract provided.


Thoughts Of A Palliative Care Nurse In Times Of Pandemic, Angela L. Simões Aug 2020

Thoughts Of A Palliative Care Nurse In Times Of Pandemic, Angela L. Simões

Patient Experience Journal

This narrative presents a series of stories (interactions) lived by a palliative care nurse during the time of COVID-19, a time when we tirelessly prepare to help the services that need us, but we have little preparation of ourselves for the changes that we will have to face in the care of our patients and families. It shares the lived experiences, difficulties, emotions lived by me but shared by so many around the world. It also tries to show that despite the scarcity of physical presence, creativity and commitment to patients and families make us go beyond ourselves and continue …


Double Mint And Double Standard: American Attitudes Toward Women Chewing Gum, 1880–1930, Brooke Sutton Aug 2020

Double Mint And Double Standard: American Attitudes Toward Women Chewing Gum, 1880–1930, Brooke Sutton

The Thetean: A Student Journal for Scholarly Historical Writing

No abstract provided.