Digital Commons Network^™

Laser Functionalization Of Carbon Membranes For Effective Immobilization Of Antimicrobial Silver Nanoparticles, Sina Nejati, Seyed Ahmad Mirbagheri, Jose Waimin, Marisa E. Grubb, Samuel Peana, David M. Warsinger, Rahim Rahimi

School of Mechanical Engineering Faculty Publications

Microbial contamination and biofilm formation are serious challenges in water filtration applications. Recently, carbon nanocomposite membranes with modified silver nanoparticles (AgNPs) have attracted much attention as compelling water purification membranes that can deactivate pathogenic bacteria and prevent biofilm formation. However, the effective attachment of AgNPs onto such carbon-based surfaces has proven difficult to accomplish via inexpensive and rapid fabrication processes. In this study, we introduce a simple laser-assisted process that enables rapid surface functionalization and immobilization of AgNPs onto carbon cloth membrane surfaces comprised of woven carbon micro fibers. The laser functionalization provides a unique modification in surface morphology of …

A Journal Of The Plague Year As A Sequel To Robinson Crusoe, Ala Alryyes

Publications and Research

No abstract provided.

Instability Of Glucocorticoid Metabolites In Coyote Scats: Implications For Field Sampling, Erika T. Stevenson, Eric M. Gese, Lorin A. Neuman-Lee, Susannah S. French

United States Department of Agriculture Wildlife Services: Staff Publications

Studying physiologic stress responses can assist in understanding the welfare of animals. One method of measuring the physiologic stress response is evaluating concentrations of glucocorticoid metabolites in feces. Previously, using an adrenocorticotropic hormone challenge, we found fecal glucocorticoid metabolite levels were a reliable indicator of physiologic stress response in coyotes (Canis latrans). We determine whether glucocorticoid metabolite concentrations remain stable when collecting feces over a 2-week period, a timeframe commonly used in scat surveys for wild canids. We collected feces from 6 captive coyotes maintained at the U.S. Department of Agriculture, Wildlife Services, National Wildlife Research Center, Predator …

Authority And Dissent In Jewish Life, Leonard Greenspoon

Purdue University Press Book Previews

Throughout the long history of Judaism, many individuals and groups have sought to wield authority on the basis of unique religious, social, familial, military, or political claims. Moving historically from the biblical period to the modern-day State of Israel, Authority and Dissent in Jewish Life discusses a range of those claims to authority from within the Jewish community itself.

Blocking C-Met/Erbb1 Axis Prevents Brain Metastasis In Erbb2+ Breast Cancer, Shailendra K. Gautam, Ranjana K. Kanchan, Jawed A. Siddiqui, Shailendra K. Maurya, Sanchita Rauth, Naveenkumar Perumal, Pranita Atri, Ramakanth C. Venkata, Kavita Mallya, Sameer Mirza, Moorthy P. Ponnusamy, Vimla Band, Sidharth Mahapatra, Maneesh Jain, Surinder K. Batra, Mohd W. Nasser

Journal Articles: Biochemistry & Molecular Biology

Brain metastasis (BrM) remains a significant cause of cancer-related mortality in epidermal growth factor receptor 2-positive (ERBB2⁺) breast cancer (BC) patients. We proposed here that a combination treatment of irreversible tyrosine kinase inhibitor neratinib (NER) and the c-MET inhibitor cabozantinib (CBZ) could prevent brain metastasis. To address this, we first tested the combination treatment of NER and CBZ in the brain-seeking ERBB2⁺ cell lines SKBrM3 and JIMT-1-BR3, and in ERBB2⁺ organoids that expressed the c-MET/ERBB1 axis. Next, we developed and characterized an orthotopic mouse model of spontaneous BrM and evaluated the therapeutic effect of CBZ and …

Fibroblast Encapsulation In Gelatin Methacryloyl (Gelma) Versus Collagen Hydrogel As Substrates For Oral Mucosa Tissue Engineering, Fahimeh Tabatabaei, Keyvan Moharamzadeh, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Purpose

Over the past decades, a variety of biomaterials have been investigated in terms of their suitability for oral mucosa tissue engineering. The aim of this study was to compare collagen and GelMA hydrogels as connective tissue scaffolds for fibroblasts and as substrates for seeding and culture of oral epithelial keratinocyte cells.

Methods

Human primary oral fibroblast and keratinocyte cells were isolated from gingival biopsies. The mixture of fibroblasts with GelMA or collagen gel were aliquoted within six-well tissue culture plate inserts and cross-linked using visible light or reconstitution buffer/heat, respectively. The viability of fibroblasts in the hydrogels was investigated …

Three-Dimensional In Vitro Oral Mucosa Models Of Fungal And Bacterial Infections, Fahimeh Tabatabaei, Keyvan Moharamzadeh, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Oral mucosa is the target tissue for many microorganisms involved in periodontitis and other infectious diseases affecting the oral cavity. Three-dimensional (3D) in vitro and ex vivo oral mucosa equivalents have been used for oral disease modeling and investigation of the mechanisms of oral bacterial and fungal infections. This review was conducted to analyze different studies using 3D oral mucosa models for the evaluation of the interactions of different microorganisms with oral mucosa. In this study, based on our inclusion criteria, 43 articles were selected and analyzed. Different types of 3D oral mucosa models of bacterial and fungal infections were …

Symposium: The California Consumer Privacy Act, Margot Kaminski, Jacob Snow, Felix T. Wu, Justin Hughes

Articles

This symposium discussion of the Loyola of Los Angeles Law Review focuses on the newly enacted California Consumer Privacy Act (CPPA), a statute signed into state law by then-Governor Jerry Brown on June 28, 2018 and effective as of January 1, 2020. The panel was held on February 20, 2020.

The panelists discuss how businesses are responding to the new law and obstacles for consumers to make effective use of the law’s protections and rights. Most importantly, the panelists grapple with questions courts are likely to have to address, including the definition of personal information under the CCPA, the application …

Do Canine Companions Reduce College Stress?, Aaron Brooking, David M. Simpson, Mindy Hatchell, Adam Van Zant, Alexis Moore, Lindsey Connors, Julianna Clarke, Sandra E. Sephton

Undergraduate Research Events

Introduction Rates of mental health concerns among college students are rising. A recent World Health Organization Survey of ~14,000 students revealed clinically concerning scores on anxiety, depression and substance use disorder for 31% [2][3]. With these high levels of clinically concerning scores in college students, great amounts of stress are the result, which have been negatively correlated with greater feelings of loneliness and lower hedonic well-being (satisfaction in life), without proper social support [6][10]. We explored potential mental health benefits of canine companions in the college setting by collecting psychosocial measures from both dog-owners and non-dog-owners assessing their levels of …

An Examination Of The Growth Of Cruelty-Free Products Available For The 18–24 Age Range., Daniela Isabel Bolivar Leon

Business ETD Collections

The topic being studied for this research is the examination of the growth of cruelty free products available for the 18 -24 age range. This is to highlight how the economy has being changing and adapting to new generations with the purpose of satisfying their needs and offer a more significant approach towards sustainability and animal testing. Animal cruelty on cosmetics is an extremely high concern for Millennials and Generations Z, those generations are constantly looking for sustainable improvements on their purchases. This case study aims to build new theories on whether a business can make profit in the long …

An Analysis Of The Awareness Of Sustainability In Food Consumption In Dublin., Thayla Penzin Goulart

Business ETD Collections

Millennials have been much more concerned with the origin of the food that they consume and its ultimate destination. It has been said that all over the world this new generation seeks for healthier options and also concerns about the use of plastic in packaging, waste reduction and compostable, reusable and recyclable materials. This is a research paper that aimed to investigate if the Dublin’s food buyers are following this global path while getting more conscious about their consumption, engaging with environmental agendas and behaving sustainably through their consumption. Through an applied structured online questionnaire, 290 participants’ results demonstrate that …

Identification Of Priority Skill Areas For Volunteer Professional Development, Car Mun Kok, Dorina Espinoza, Steven Worker, Charles Go

Journal of Youth Development

Youth development programs often rely on volunteers to deliver programming to young people. Our study explored the skills and competencies volunteers self-identified as important for their roles. We analyzed qualitative responses to 2 open-ended questions asking University of California 4-H volunteers to identify priority skills to aid in their volunteer development. Using inductive thematic analysis, we developed a coding scheme to analyze 1,144 responses. Participants reported the need for professional development in content-specific areas, program management basics, and child development. Volunteers also reported desiring training in educational practices, organizational skills, specific volunteer roles, and communication skills. The modalities through which …

The Nature Of Standing, Matthew I. Hall, Christian Turner

Scholarly Works

Standing to raise a claim before a judicial tribunal is notoriously contested. Federal courts during the last century developed an increasingly rule-like and rigid doctrine around the concept of private injury to govern access to the federal forum. Some states followed the federal lead. Others have created important exceptions, and even in federal courts, issues like organizational standing, legislative standing, and standing of qui tam relators have proved controversial. We describe a broader taxonomy of agenda control rules, of which standing rules are a special case, to understand why and how courts and other institutions govern their choices of what …

Track My Ride, Cesar Padron Ramirez, Jady Silva Martins, Maria De La Luz Lagunas Modesto, Rodolfo Carvajal Marquez, Yuri Braga

ICT

Cycling has become more and more popular as a healthy activity and a transport option across many countries. This is not different in Ireland, a country where in April 2016, 56,837 people cycled to work; an increase of 43% since 2011 (Central statistics office, 2017).

Irish Government “committed to developing cycling as one of the most desirable modes of travel by 2020” as it plays an indispensable role in people’s lives (Sustainable transport division - department of transport, tourism and sport, 2009).

The “Balance” team managed to visualize that a strong cycling culture was becoming important in Ireland. Hence our …

[Chain Up Group] Applied Technology Group Project, Maria Beluz Suarez, Haein Kim

ICT

This document presents the draft of the introductory chapter as well as the research and planning aspects of developing a text hosting service application based on block chain technology named‘Chain UP. This report represents part I of the continuous assessment of the year-module named Applied Technology Group Project for the 3rd year of the Information Technology course at CCT College Dublin. This chapter contains an introduction to Blockchain’s concepts and an overview of its benefits and the latest industry applications of this technology, specifically the financial services industry and the data security industry. In the next chapters, we will discuss …

Digital Scholarship Embedded In Pedagogy: Building Blocks For Computational Confidence And Digital Literacy Skills, Amy Gay

Library Scholarship

This presentation was given at the International Virtual Symposium on Digital Scholarship (http://www.lislinks.com/events/international-virtual-symposium-on-digital-scholarship), hosted by Tamil Nadu Veterinary and Animal Sciences University, India. It covers the integration of digital scholarships projects into pedagogy, including examples and digital platforms and open source software to get started.

Cathedrals Of The Mind: Theological Method And Speculative Renewal In Trinitarian Theology, Ryan Hemmer

Dissertations (1934 -)

The aim of this work is twofold. First, it labors to retrieve from the past a normative account of speculative theological method, in protest of the anti-speculative fashions and attitudes that have prevailed among theologians since the Second Vatican Council. Second, and in tension with the first aim, this study outlines the respects in which conciliar and post-conciliar developments in history, anthropology, philosophy, and cultural analysis—the same developments that led to speculative theology’s fall from favor—are the means by which speculative theology might be renewed and made useful in theology today. The second chapter squares up to speculative theology’s critics …

The Role Of System Xc- In Cognition: The Importance Of Neuron-Astrocyte Signaling, Evan Michael Hess

Dissertations (1934 -)

The biological basis of human intelligence is largely a mystery, but likely required evolutionary adaptations to achieve the information processing capacity needed to expand the complexity of cognition among species. The link between evolutionary expansion of signaling complexity in the brain and cognition has largely focused on neuronal mechanisms, in part because information processing has historically been attributed to these cells. However, astrocytes are emerging as a second type of brain cell that is capable of processing information due to their capacity to release glutamate and, thereby, regulate neural circuits. Hence, a modern question is whether astrocytes contributed to the …

Inquiry And Provocation: The Use Of Ambiguity In Sixteenth-Century English Political Satire, Jason James Zirbel

Dissertations (1934 -)

Nearly all literary theories for a millennium have defined satire according to its linguistic clarity and moral certainty. Not until recently have theorists such as Dustin Griffin recognized that satire often comprises an ambiguity that moves it beyond the mere policing of established moral boundaries. This project considers how four sixteenth-century satirists—Thomas Wyatt, George Gascoigne, Thomas Deloney, and Thomas Nashe—exploited satire’s capacity for open-ended inquiry to address the rapid political and economic changes that typified the early modern period. Rather than relying on established moral codes to domesticate uncertainty, these writers used satire to explore and analyze government bureaucratization, the …

Design Of Novel Experiments And Analyses For Head And Spine Trauma Biomechanics, John Robert Humm

Dissertations (1934 -)

Previous biomechanics research studies have used both whole-body and isolated postmortem human surrogate experiments to define human injury tolerances, advance safety in injury producing environments, and promulgate standards for design of injury mitigating systems. Recent developments in transportation and sports-related fields have led to an increasing need to determine tolerances for combined loading (multi-axis) scenarios. This dissertation demonstrates the efficacy of the novel experimental design and analysis to head and spine trauma in these modalities. The first topic was the design of a novel experiment to examine the effect oblique loading on the tension tolerance of the lumbar spine. To …

Chronic Variable Stress Induces Avolition And Disrupts Corticoaccumbens Encoding Of Approach Cues, Mitchell Spring

Dissertations (1934 -)

Disorders in the ability to process, evaluate, and interact with rewards are hallmarks of a range of mental illnesses. Such disorders are multi-faceted and arise from altered activity throughout diffuse brain regions. Chronic variable stress (CVS) is an oft-used tool for modeling reward-related disorders in preclinical research because it impairs the function of multiple brain regions and causes a range of severe hedonic and motivational deficits. While much research has focused on the former, the latter is poorly characterized. A panel of behavioral tests was used to characterize the effect of CVS exposure on different facets of reward related behaviors …

Study Of Techniques To Enhance The Performance Of Concrete Members Strengthened By Externally Bonded Composite Materials, Zhao Wang

Dissertations (1934 -)

External bonding of fiber reinforced polymer (FRP) composite materials has been widely recognized as a popular technique for strengthening concrete structures. To find advanced strategies to improve the bond behavior of externally bonded composites strengthened concrete, three major tasks were conducted in this study: experimental work, finite element (FE) analysis, and reliability analysis. The mechanical properties and the deterioration due to water absorption of carbon nanofibers (CNFs) epoxy composites with different contents of CNFs were tested through uniaxial tensile test. According to the tensile test results, adding CNFs could significantly enhance the tensile behavior for epoxy resin. Because adding proper …

Deep Learning For Quantitative Susceptibility Mapping Reconstruction, Juan Liu

Dissertations (1934 -)

Quantitative susceptibility mapping (QSM) is a magnetic resonance imaging (MRI) technique that estimates tissue magnetic susceptibility from Larmor frequency offset measurements. The generation of QSM requires solving ill-posed background field removal (BFR) and field-to-source inversion problems. Incorrect BFR often introduces erroneous local field outputs and subsequently affects susceptibility quantification accuracy. Inaccurate field-to-source inversion often causes large susceptibility estimation errors that appear as streaking artifacts in the QSM, especially in massive hemorrhagic regions. Because current QSM techniques struggle to generate reliable QSM, the clinical translation of QSM is greatly hindered. Recently, deep learning (DL) has achieved state-of-the-art performance in many computer …

Validation And Application Of A Novel Target-Based Whole-Cell Screen To Identify Antifungal Compounds, Christian Alexander Dejarnette

Theses and Dissertations (ETD)

Traditional approaches to drug discovery are inefficient and have several key limitations that constrain our capacity to rapidly identify and develop novel experimental therapeutics. To address this, we have devised a second-generation target-based whole-cell screening assay based on the principles of competitive fitness, which can rapidly identify target-specific and physiologically-active compounds. Briefly, strains expressing high, intermediate, and low levels of a preselected target protein were constructed, tagged with spectrally distinct fluorescent proteins (FPs), and mixed together. The pooled strains were then grown in the presence of various small molecules, and the relative growth of each strain within the mixed culture …

From The Editors, Ezra Rosser, Robert Dinerstein

Scholarly Articles in Law Reviews & Journals

Although this issue arrives on desks roughly two years after the start of the coronavirus pandemic, it offers a degree of continuity with our usual fare concerning scholarship about legal education. Our next double-length issue will explore in depth matters of teaching modality, technology, and change connected with the ongoing pandemic. This issue offers fresh perspectives on matters of long-standing concern-line drawing, pro bono requirements, pedagogy, law student instruction of high school students, and bar exams. We found the articles, as well as the three book reviews that fill out this issue, to be engaging and insightful and we hope …

Gene Expression Responses Of Larval Gopher (Sebastes Carnatus) And Blue (S. Mystinus) Rockfish To Ocean Acidification And Hypoxia, Jacoby Baker

Capstone Projects and Master's Theses

Global climate change is driving shifts in ocean chemistry, which combined with intensification of coastal upwelling, reduces ocean pH and dissolved oxygen (DO) content in the nearshore habitats of the California Current System. Physiological plasticity, within and across generations, might be especially important for long-lived, late-to-mature species, like rockfishes (genus Sebastes), that may be unable to keep pace with climate change via genetic adaptation. Rockfishes exhibit matrotrophic viviparity and may be able to buffer their offspring from environmental stress through early developmental exposure or transgenerational plasticity (non-genetic inheritance of phenotypes). In this study, mature female gopher (S. carnatus …

City Of Long Beach Coyote Management Project, Eric G. Strauss, Michele Romolini, Melinda Weaver

Center for Urban Resilience Reports

EXECUTIVE SUMMARY

Staff from the Loyola Marymount University Center for Resilience, in collaboration with officials from the City of Long Beach conducted a multiyear analysis of coyote ecology, risk, and management options to be implemented. The project was designed to incorporate local data, regional information and national examples to be applied to the challenges of coyote management in Long Beach. The project was initiated in response to increase concern about the safety of coyotes living within the city and their impact on domestic animals, especially cats. The project occurred at a prescient period in urban coyote research as many parallel …

Paying For The Privilege Of Punishment: Reinterpreting Excessive Fines Clause Doctrine To Allow State Prisoners To Seek Relief From Pay-To-Stay Fees, Kristen M. Haight

William & Mary Law Review

Across the country, the criminal justice system is becoming both more private and more expensive. Some prison systems have come to rely on private contractors for electronic monitoring, probation, pretrial services, and incarceration services. At the same time, criminal justice fees are exploding, including fees charged to inmates for their “room and board” while in prison. These fees, sometimes called “pay-to-stay,” are imposed at the state and county level, and how they are applied varies widely. Some take into account inmates’ ability to pay the fees, or the effect on their families. Some do not. Some only apply to prisoners …

Coordinated River Infrastructure Decisions Improve Net Social-Ecological Benefits, Samuel G. Roy, Adam Daigneault, Joseph Zydlewski, Allison Truhlar, Sean Smith, Shaleen Jain, David Hart

New Hampshire EPSCoR

We explore the social, ecological, economic, and technical dimensions of sustainable river infrastructure development and the potential benefits of coordinating decisions such as dam removal and stream crossing improvement. Dam removal is common practice for restoring river habitat connectivity and ecosystem health. However, stream crossings such as culverts are often 15 times more abundant than dams and may pose similar ecological impacts. Using multi-objective optimization for a model system of 6100 dams and culverts in Maine, USA, we demonstrate substantial benefit-cost improvements provided by coordinating habitat connectivity decisions. Benefit-cost efficiency improves by two orders of magnitude when coordinating more decisions …

Law On The Half Shell: Applying A Right-To-Farm Framework To Virginia's Aquaculture Industry, Matt Woodward, Andrew Corso

Virginia Coastal Policy Center

Beginning in the 1970s and 1980s, states responded to mounting land use conflicts by enacting Right-to-Farm or “RTF” laws. These laws serve to protect farmers and other agricultural producers by shielding their operations from nuisance suits. Virginia’s RTF law has helped to resolve land use conflicts and has helped to protect an agricultural industry that is both culturally and economically vital to the state.

Commercial shellfish activity has also historically proven vital to Virginia’s unique coastal identity and economy. Further, over the last several decades, Virginia’s diverse aquaculture industry has grown, making Virginia one of the leading producers of aquacultural …