Digital Commons Network^™

Low-Dose Radiation Therapy (Ldrt) For Covid-19: Benefits Or Risks?, Pataje G. Prasanna, Gayle E. Woloschak, Andrea L. Dicarlo, Jeffrey C. Buchsbaum, Dörthe Schaue, Arnab Chakravarti, Francis A. Cucinotta, Silvia C. Formenti, Chandan Guha, Dale J. Hu, Mohammad K. Khan, David G. Kirsch, Sunil Krishnan, Wolfgang W. Leitner, Brian Marples, William Mcbride, Minesh P. Mehta, Shahin Rafii, Elad Sharon, Julie M. Sullivan, Ralph R. Weichselbaum, Mansoor M. Ahmed, Bhadrasain Vikram, C. Norman Coleman, Kathryn D. Held

Health Physics and Diagnostic Sciences Faculty Research

©2020 by Radiation Research Society. All rights of reproduction in any form reserved. The limited impact of treatments for COVID-19 has stimulated several phase 1 clinical trials of whole-lung low-dose radiation therapy (LDRT; 0.3-1.5 Gy) that are now progressing to phase 2 randomized trials worldwide. This novel but unconventional use of radiation to treat COVID-19 prompted the National Cancer Institute, National Council on Radiation Protection and Measurements and National Institute of Allergy and Infectious Diseases to convene a workshop involving a diverse group of experts in radiation oncology, radiobiology, virology, immunology, radiation protection and public health policy. The workshop was …

Academic Senate - Agenda, 11/10/2020, Academic Senate

Academic Senate Agendas

No abstract provided.

Kir6.1- And Sur2-Dependent Katp Over-Activity Disrupts Intestinal Motility In Murine Models Of Cantu Syndrome, Nathaniel W York, Helen Parker, Zili Xie, David Tyus, Maham A Waheed, Zihan Yan, Dorothy K Grange, Maria S Remedi, Sarah K England, Hongzhen Hu, Colin G Nichols

Open Access Publications

Cantύ Syndrome (CS), caused by gain-of-function (GOF) mutations in pore-forming (Kir6.1, KCNJ8) and accessory (SUR2, ABCC9) ATP-sensitive potassium (KATP) channel subunit genes, is frequently accompanied by gastrointestinal (GI) dysmotility, and we describe one CS patient who required an implanted intestinal irrigation system for successful stooling. We used gene-modified mice to assess the underlying KATP channel subunits in gut smooth muscle, and to model the consequences of altered KATP channels in CS gut. We show that Kir6.1/SUR2 subunits underlie smooth muscle KATP channels throughout the small intestine and colon. Knock-in mice, carrying human KCNJ8 and ABCC9 CS mutations in the endogenous …

Rsif Weekly Vol.1 No.24, Regional Scholarship And Innovation Fund (Rsif)

Rsif Newsletters

No abstract provided.

Impacts On Climate Change On Multiple Use Management Of Bureau Of Land Management Land In The Intermountain West, Usa, Elaine M. Brice, Brett A. Miller, Hongchao Zhang, Kirsten Goldstein, Scott N. Zimmer, Guenchik J. Grosklos, Patrick Belmont, Courtney G. Flint, Jennifer E. Givens, Peter B. Adler, Mark W. Brunson, Jordan W. Smith

Environment and Society Faculty Publications

Although natural resource managers are concerned about climate change, many are unable to adequately incorporate climate change science into their adaptation strategies or management plans, and are not always aware of or do not always employ the most current scientific knowledge. One of the most prominent natural resource management agencies in the United States is the Bureau of Land Management (BLM), which is tasked with managing over 248 million acres (>1 million km²) of public lands for multiple, often conflicting, uses. Climate change will affect the sustainability of many of these land uses and could further increase …

Coral Reef Restoration In The Tropical West Atlantic Amid The Covid-19 Pandemic, Linden Cheek

USF Tampa Graduate Theses and Dissertations

Climate change is increasing threats to coasts, both from storm surge and sea level rise. Healthy coral reefs provide reduction in storm surges, wave energy, coastal flooding and everyday erosion, and are found across a variety of spatial scales. Given the state of coral reefs worldwide, active Coral Reef Restoration (CRR) in emerging as a necessary component of coastal protection. CRR can be classified as a nature-based solutions (NbS) for coastal protection that also provides a multitude of ecosystem-based services to both humans and other life. Nearly all literature on coral restoration efforts assume a steady-state of human-ecological interactions, but …

Save Water Drink Wine: Challenges Of Implementing The Ethnography Of The Temecula Valley Wine Industry Into Food-Energy-Water Nexus Decision-Making, Zaida E. Darley

USF Tampa Graduate Theses and Dissertations

This study demonstrates the interrelationships of people, food, energy, and water associated with Temecula Valley’s wine industry and reveals contradictions and biases in how people view these resources, which ultimately shape management and policies. The FEW (Food, Energy, and Water) Nexus is an approach increasingly used by policy- and decision-makers to understand the interrelationship of several resources. However, a FEW Nexus approach often lacks in social aspects that influence environmentally and economically sustainable outcomes, especially in the wine and wine tourism industry. When quantitative and qualitative data are available, the other challenge is which assessment to use. Two assessments often …

Structural Basis Of Ion Transport And Inhibition In Ferroportin, Yaping Pan, Zhenning Ren, Shuai Gao, Jiemin Shen, Lie Wang, Zhichun Xu, Ye Yu, Preetham Bachina, Hanzhi Zhang, Xiao Fan, Arthur Laganowsky, Nieng Yan, Ming Zhou

Faculty, Staff and Students Publications

Ferroportin is an iron exporter essential for releasing cellular iron into circulation. Ferroportin is inhibited by a peptide hormone, hepcidin. In humans, mutations in ferroportin lead to ferroportin diseases that are often associated with accumulation of iron in macrophages and symptoms of iron deficiency anemia. Here we present the structures of the ferroportin from the primate Philippine tarsier (TsFpn) in the presence and absence of hepcidin solved by cryo-electron microscopy. TsFpn is composed of two domains resembling a clamshell and the structure defines two metal ion binding sites, one in each domain. Both structures are in an outward-facing conformation, and …

Differential Functional Connectivity Underlying Asymmetric Reward-Related Activity In Human And Nonhuman Primates, Alizée Lopez-Persem, Léa Roumazeilles, Davide Folloni, Kévin Marche, Elsa F. Fouragnan, Nima Khalighinejad, Matthew F.S. Rushworth, Jérôme Sallet

School of Psychology

The orbitofrontal cortex (OFC) is a key brain region involved in complex cognitive functions such as reward processing and decision making. Neuroimaging studies have reported unilateral OFC response to reward-related variables; however, those studies rarely discussed this observation. Nevertheless, some lesion studies suggest that the left and right OFC contribute differently to cognitive processes. We hypothesized that the OFC asymmetrical response to reward could reflect underlying hemispherical difference in OFC functional connectivity. Using resting-state and reward-related functional MRI data from humans and from rhesus macaques, we first identified an asymmetrical response of the lateral OFC to reward in both species. …

Engineering Characteristics Of Nest Building Geomaterials Used By Mud Dauber Species, Noura Saleh

LSU Master's Theses

Mud dauber wasps construct their nests using soil from adjacent areas. Mud dauber nests have been studied from an entomological perspective. However; the properties of the nest material remain unexplored from a soil engineering perspective. This study investigated the physical and mechanical properties of the nest soil for use in future bio-inspired design to improve soil behavior as a construction material. To achieve this goal, nests from three mud dauber species (black and yellow, organ pipe, and steel blue) were collected from locations near Baton Rouge, Louisiana. The shape, weight, moisture content, organic content, and specific gravity of the nests …

The Echo: November 9, 2020, Taylor University

2020-2021 (Volume 108)

Biden or Trump? — Taylor shows posture toward election — World Vision marathon and half marathon — New class says anyone can run a marathon — Pursuing passions for positive impact — Jesse Brown uses free time to care for creation — Caring for our health — Problems with salaries for educators — The problem of diversity in film, TV — Foundation’s spooktacular haunted house — Taylor’s Rising Artists — Her path to the classroom — Taylor alum spark change — Finish strong, students — ‘Parnassus’ aims to further unify writers — Senior artist discusses passion for people — ‘Twilight’ …

Crocodile Hunting In The Marian Library, Henry Handley

Marian Library Blog Archive

A tweet about a taxidermied croc hanging from the rafters of an Italian church sends a librarian on a quest for answers.

Spring 2021 M.A. In Law, Justice & Culture Course Offerings, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Employees Finding Help For Anxiety In Mystrength App, Matt Windsor

Browse All News

No abstract provided.

Using Robot Animal Companions In The Academic Library To Mitigate Student Stress, Autumn P. Edwards, Chad Edwards, Bryan Abendschein, Juliana Espinosa, Jonathan Scherger, Patricia Fravel Vander Meer

University Libraries Faculty & Staff Publications

The purpose of this paper is to interrogate the relationship between self-reported levels of acute stress, perceived social support, and interactions with robot animals in an academic library. The authors hypothesized: 1. participants would report lower stress and higher positive affect after their interaction with a robot support animal; 2. perceived supportiveness of the robot support animal would positively predict the amount of stress reduction the participants reported.

The authors hosted a robot petting zoo in the main library at a large Midwestern university during finals week. Participants were asked to rate their stress level prior to interacting with the …

Ceramide Analog [18F]F-Hpa-12 Detects Sphingolipid Disbalance In The Brain Of Alzheimer’S Disease Transgenic Mice By Functioning As A Metabolic Probe, Simone M. Crivelli, Daan Van Kruining, Qian Luo, Jo A. A. Stevens, Caterina Giovagnoni, Andreas Paulus, Matthias Bauwens, Dusan Berkes, Helga E. De Vries, Monique T. Mulder, Jochen Walter, Etienne Waelkens, Rita Derua, Johannes V. Swinnen, Jonas Dehairs, Felix M. Mottaghy, Mario Losen, Erhard Bieberich, Pilar Martinez-Martinez

Physiology Faculty Publications

The metabolism of ceramides is deregulated in the brain of Alzheimer’s disease (AD) patients and is associated with apolipoprotein (APO) APOE4 and amyloid-β pathology. However, how the ceramide metabolism changes over time in AD, in vivo, remains unknown. Distribution and metabolism of [¹⁸F]F-HPA-12, a radio-fluorinated version of the ceramide analog N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl) dodecanamide, was investigated in the brain of AD transgenic mouse models (FAD) on an APOE4 or APOE3 genetic background, by positron emission tomography and by gamma counter. We found that FAD mice displayed a higher uptake of [¹⁸F]F-HPA-12 in the brain, independently from the APOE4 …

A Cross-Cultural Study On The Relationship Between Environmental Awareness And Social Media Use: Saudi Arabia Vs United States, Mohammed Alsahafi

Theses

For many countries today, environmental sustainability is a subject of concern, and the world has witnessed the rise of environmental activism in recent years. Social media is increasingly being used by relevant stakeholders to raise environmental awareness. This study explores the relationship between social media use and environmental awareness from a cross-cultural perspective. Building upon previous research, this study compares social media use, environmental awareness, and their relationship between Saudi Arabian and American college students. Survey data was collected from a convenient sample of 266 Saudi Arabian and 290 American college students on their use of Facebook, Twitter, and Instagram …

Pond Scum: Partygeddon, Zachary Kirwin

Theses

Pond Scum: Partygeddon is a film about three lowlifes, Algee, Oozer and Ewwglena, who set out to throw a party to end all parties, and get a little more than they bargained for. Their scrappy friendship will be all that keeps them alive by the end of the night.

The film is hand drawn 2d animation created in Toon Boom Harmony and composited with original, hand-painted, watercolor backgrounds in Adobe After Effects. The soundtrack is a mix of original songs by the bands Pond Scum, Lord Scum, and Sh*t Rat.

This paper is both a documentation of the process of …

A Genomic Catalog Of Earth’S Microbiomes, Brian Hedlund, More Than 200 Other International Authors

Life Sciences Faculty Research

The reconstruction of bacterial and archaeal genomes from shotgun metagenomes has enabled insights into the ecology and evolution of environmental and host-associated microbiomes. Here we applied this approach to >10,000 metagenomes collected from diverse habitats covering all of Earth’s continents and oceans, including metagenomes from human and animal hosts, engineered environments, and natural and agricultural soils, to capture extant microbial, metabolic and functional potential. This comprehensive catalog includes 52,515 metagenome-assembled genomes representing 12,556 novel candidate species-level operational taxonomic units spanning 135 phyla. The catalog expands the known phylogenetic diversity of bacteria and archaea by 44% and is broadly available for …

Predictors Of Manual Dexterity In Simulation-Based Cataract Surgery, Laura Palazzolo, Anna Kozlova, John J. Laudi, Allison E. Rizzuti

Journal of Academic Ophthalmology

Abstract

Introduction The aim of this study is to determine if prior experience with fine motor hobbies influences a surgeon-in-training's performance on a cataract surgical simulator.

Materials and Methods Medical students (n = 70) performed navigation, forceps, and capsulorhexis simulations using the Eyesi Ophthalmosurgical Simulator. Participants were surveyed regarding fine motor hobby experiences, including musical instruments, video games, sewing, knitting, origami, painting, crafting, jewelry making, drawing, and extracurricular dissection.

Results Medical students with extracurricular dissection experience, including work in research laboratories involving microscopic animal dissection, did significantly better on the forceps simulator task (p = 0.009). Medical students with drawing …

Phosphodiesterase 5 (Pde5) Restricts Intracellular Cgmp Accumulation During Enterotoxigenic Escherichia Coli Infection, Jennifer Foulke-Abel, Huimin Yu, Laxmi Sunuwar, Ruxian Lin, James M Fleckenstein, James B Kaper, Mark Donowitz

2020-Current year OA Pubs

Diarrhea caused by enterotoxigenic

Young Versus Aged Microbiota Transplants To Germ-Free Mice: Increased Short-Chain Fatty Acids And Improved Cognitive Performance, Juneyoung Lee, Venugopal R Venna, David J Durgan, Huanan Shi, Jacob Hudobenko, Nagireddy Putluri, Joseph Petrosino, Louise D Mccullough, Robert M Bryan

Faculty, Staff and Students Publications

Aging is associated with cognitive decline and decreased concentrations of short-chain fatty acids (SCFAs) in the gut. SCFAs are significant in that they are protective to the gut and other organs. We tested the hypothesis that the aged gut microbiome alone is sufficient to decrease SCFAs in the host and produce cognitive decline. Fecal transplant gavages (FTGs) from aged (18–20 months) or young (2–3 months) male C57BL/6 mice into germ-free male C57BL/6 mice (N = 11 per group) were initiated at ~3 months of age. Fecal samples were collected and behavioral testing was performed over the study period. Bacterial community …

Predicting Quality Of Delivery Metrics For Adaptive Video Codec Sessions, Obinna Izima, Ruairí De Fréin, Mark Davis

Conference papers

Predicting video quality will continue to be an active area of research given the dominance of video traffic for years to come. Network service practitioners that are poised to handle the strain on the existing limited bandwidth constraints are better placed to be SLA-compliant. The dynamic and time-varying nature of cloud-hosted services require improved techniques to realize accurate models of the systems. To address this challenge: (1) we propose Codec-aware Network Adaptation Agent (cNAA), an online light-weight data learning engine that achieves accurate and correct predictions of quality of delivery (QoD) metrics, namely jitter for video services. cNAA achieves this …

Antimicrobial Resistance In Enteric Bacteria: Current State And Next-Generation Solutions, M J Wallace, S R S Fishbein, G Dantas

2020-Current year OA Pubs

Antimicrobial resistance is one of the largest threats to global health and imposes substantial burdens in terms of morbidity, mortality, and economic costs. The gut is a key conduit for the genesis and spread of antimicrobial resistance in enteric bacterial pathogens. Distinct bacterial species that cause enteric disease can exist as invasive enteropathogens that immediately evoke gastrointestinal distress, or pathobionts that can arise from established bacterial commensals to inflict dysbiosis and disease. Furthermore, various environmental reservoirs and stressors facilitate the evolution and transmission of resistance. In this review, we present a comprehensive discussion on circulating resistance profiles and gene mobilization …

Impacts And Adaptation To Climate Change In Beef Production Systems In Central Queensland, David H. Cobon, N. R. Toombs

IGC Proceedings (1977-2023)

No abstract provided.

The Climate Change Challenge For Managed Grasslands In New Zealand, Judy Lawrence

IGC Proceedings (1977-2023)

No abstract provided.

Carbon Stocks And Environmental Controls Of China's Grasslands, Jingyun Fang, Yuanhe Yang, Wenhong Ma, Anwar Mohammat

IGC Proceedings (1977-2023)

No abstract provided.

Study Of Effects Of Irrigation With Waste Water On Growing Season Of Bromus Tecrum, Nafiseh Taghavi, Mohammad Jaafari

IGC Proceedings (1977-2023)

No abstract provided.

Reframing Joseph Cardinal Bernardin’S Consistent Ethic Of Life In The Light Of The Crisis Of Our Common Home And Pope Francis’ Integral Ecology, Anatoly Angelo R. Aseneta

Theology Department Faculty Publications

The article is based from the a defended dissertation of the same title. As raised by Pope Francis in Laudato Si’ and as evidenced by the various ecological problems we face, the crisis of our common home harms both non-human and human life. It is becoming more evident that to consistently defend human life inevitably means caring for our common home. Joseph Cardinal Bernardin’s moral vision of a consistent ethic of life (CEL), reframed in the light of the crisis of our common home and Francis’ call for an integral ecology, provides a moral framework that inseparably links the protection …

Adventures In Remote Learning, Dean Norman

Erma Bombeck Writers' Workshop Blog

Maybe at this time when classroom learning is risky, parents should take the kids outdoors. Remote from the computer screen, too.