Digital Commons Network^™

Agenda, November 17, 2020, Programs Committee

Programs Committee (PC)

No abstract provided.

Proposal Budgeting (Pre-Award Planning For Post-Award Administration), Mickey Mclaurin, Renita Gray

ORSP Presentations

No abstract provided.

Selective Interactions Of O-Methylated Flavonoid Natural Products With Human Monoamine Oxidase-A And -B, Narayan D. Chaurasiya, Jacob Midiwo, Pankaj Pandey, Regina N. Bwire, Robert J. Doerksen, Ilias Muhammad, Babu L. Tekwani

Faculty and Student Publications

A set of structurally related O-methylated flavonoid natural products isolated from Senecio roseiflorus (1), Polygonum senegalense (2 and 3), Bhaphia macrocalyx (4), Gardenia ternifolia (5), and Psiadia punctulata (6) plant species were characterized for their interaction with human monoamine oxidases (MAO-A and -B) in vitro. Compounds 1, 2, and 5 showed selective inhibition of MAO-A, while 4 and 6 showed selective inhibition of MAO-B. Compound 3 showed ~2-fold selectivity towards inhibition of MAO-A. Binding of compounds 1-3 and 5 with MAO-A, and compounds 3 and 6 with MAO-B was reversible and not time-independent. The analysis of enzyme-inhibition kinetics suggested a …

Rivalry Appeals In Advertising: Distinctiveness Versus Inclusiveness, David Stahr

Honors Projects in Marketing

The main objective of the research is to study how convenience and shopping products impact how consumers react to rivalry appeals in advertisements. The authors examine the effectiveness of rivalry appeals in advertisements and how they are impacted by the product type considered by consumers. In two studies, a 2 (prime: distinctiveness vs. inclusiveness) x 2 (message: competition vs. collaboration) ANOVA methodology was conducted on survey data. In Study 1, participants primed with distinctiveness (inclusiveness) and considering convenience products experienced an assimilation effect where they preferred competitive (collaborative) rivalry appeals. In Study 2, participants primed with distinctiveness (inclusiveness) and considering …

University Ethics: The Status Of The Field, Matthew J. Gaudet

General Engineering

This paper’s task is to provide a summary of this nascent field at its current state of development. First, I trace Keenan’s work to germinate university ethics as a new field worthy of study. Second, I examine several precursors to university ethics and how these precursors continue to provide fertile soil for the field from which this new field may continue to grow. Next, I survey the current state of the field, identifying where the field has already begun to bloom and bear fruit. Finally, I look to the future of the field, identifying issues that are either already plaguing …

Rivalry Appeals In Advertising: Distinctiveness Versus Inclusiveness, David Stahr, Sukki Yoon, Kacy Kim

Honors Projects in Marketing

The main objective of the research is to study how convenience and shopping products impact how consumers react to rivalry appeals in advertisements. The authors examine the effectiveness of rivalry appeals in advertisements and how they are impacted by the product type considered by consumers. In two studies, a 2 (prime: distinctiveness vs. inclusiveness) x 2 (message: competition vs. collaboration) ANOVA methodology was conducted on survey data. In Study 1, participants primed with distinctiveness (inclusiveness) and considering convenience products experienced an assimilation effect where they preferred competitive (collaborative) rivalry appeals. In Study 2, participants primed with distinctiveness (inclusiveness) and considering …

Columbine And The Myth Of The Juvenile Superpredator, Christopher M. Mosqueda

Theses and Dissertations

Mass media has great influence over its audience. When a sensational story hits the news waves, the general public's attention is instantly riveted to the television screen. News stories that involve the deaths of innocent people often create a culture of fear, fuel false narratives, and scatter misinformation. In fact, this culture of fear, coupled with misleading information, created the myth of the juvenile superpredator, a phrase coined by DiIulio in the early 1990s. The stereotyped superpredator was a homicidal, uncontrollable youth hiding within areas where crime and violence are rare. In particular, this myth was propagated following the massacre …

Design And Implementation Of Cloth Virtual Simulation System For Group Performance, Xiaotian Sun, Boxiang Xiao, Zhengdong Liu

Journal of System Simulation

Abstract: Clothing plays an important role in group performance activities and affects directly the overall performance effect. In order to achieve the goal of virtual design and virtual exercise of group performance costume, a virtual simulation system is designed and implemented. The human body model is established by CLO3D, and then individual clothing model is constructed. After the human body and clothing model are imported into Unity, the clothing material is adjusted and the texture map is added. The group model is generated by copying individual clothing models of human body and clothing in Unity. The interactive interface of virtual …

Conduct Of Clinical Trials In The Era Of Covid-19: Jacc Scientific Expert Panel., Mitchell A. Psotka, William T. Abraham, Mona Fiuzat, Gerasimos Filippatos, Joann Lindenfeld, Tariq Ahmad, Ankeet S. Bhatt, Peter E. Carson, John G.F. Cleland, G. Michael Felker, James L. Januzzi, Dalane W. Kitzman, Eric S. Leifer, Eldrin F. Lewis, John J.V. Mcmurray, Robert J. Mentz, Scott D. Solomon, Norman Stockbridge, John R. Teerlink, Muthiah Vaduganathan, Orly Vardeny, David J. Whellan, Janet Wittes, Stefan D. Anker, Christopher M. O'Connor

Department of Medicine Faculty Papers

The coronavirus disease-2019 (COVID-19) pandemic has profoundly changed clinical care and research, including the conduct of clinical trials, and the clinical research ecosystem will need to adapt to this transformed environment. The Heart Failure Academic Research Consortium is a partnership between the Heart Failure Collaboratory and the Academic Research Consortium, composed of academic investigators from the United States and Europe, patients, the U.S. Food and Drug Administration, the National Institutes of Health, and industry members. A series of meetings were convened to address the challenges caused by the COVID-19 pandemic, review options for maintaining or altering best practices, and establish …

Weighing The Evidence For The Abundant-Center Hypothesis, Tad Dallas, Luca Santini, Alan Hastings

Faculty Publications

The abundant-center hypothesis posits that species density should be highest in the center of the geographic range or climatic niche of a species, based on the idea that the center of either will be the area with the highest demographic performance (e.g., greater fecundity, survival, or carrying capacity). While intuitive, current support for the hypothesis is quite mixed. Here, we discuss the current state of the abundant-center hypothesis, highlighting the relatively low level of support for the relationship. We then discuss the potential reasons for this lack of empirical support, emphasiz-ing the inherent ecological complexity which may prevent the observation …

Experiences Among Adults And Adolescents During The Covid-19 Pandemic From Four Locations Across Kenya—Study Description, Timothy Abuya, Karen Austrian, Adan Isaac, Beth Kangwana, Faith Mbushi, Eva Muluve, Daniel Mwanga, Thoai Ngo, Mercy Nzioki, Rhoune Ochako, Jessie Pinchoff, Ben Tidwell, John Wanyungu, Corinne White

Poverty, Gender, and Youth

To control the spread of coronavirus, the COVID-19 National Emergency Response Committee (NERC) in Kenya, chaired by the Ministry of Health (MOH), has implemented prevention and mitigation measures. To inform the Government of Kenya’s shorter- and longer-term response strategies, the Population Council COVID-19 study team utilizes rapid phone-based surveys to collect information on knowledge, attitudes, practices and needs among a longitudinal cohort of heads of household sampled from existing prospective cohort studies. The first was carried out across five Nairobi urban informal settlements; the baseline survey (n=2,009) was conducted March 30–31 with subsequent follow-up surveys conducted April 13–14 (n=1,764), May …

Compounds For The Treatment Of Neurodegenerative Diseases, Jianfeng Cai, Chuanhai Cao

USF Patents

Disclosed herein are compounds for the treatment of neurodegenerative diseases and compositions comprising the same.

Dysbiotic Lesional Microbiome With Filaggrin Missense Variants Associate With Atopic Dermatitis In India, Shankha Nath, Naina Kumari, Debabrata Bandyopadhyay, Neloy Sinha, Partha P. Majumder, Rupak Mitra, Souvik Mukherjee

Journal Articles

Background: Atopic Dermatitis (AD) has been associated with the loss of function (LoF) mutations in Filaggrin (FLG) gene and increase in relative abundance of specific microbes in the lesional skin, predominantly in Caucasians. Our study aims to determine, in Indian AD patients, (a) the prevalence of FLG LoF and missense mutations, and (b) the nature and extent of dysbiosis and altered microbial pathways with and without mutations in FLG. AD patients (n = 34) and healthy controls (n = 54) were recruited from India in this study and shotgun sequencing was carried out in a subset of samples with adequate …

Autumn Brown Art399 Portfolio, Autumn Brown

Professional Practices (ART 399)

It is easier to approach a difficult topic if it isn’t immediately posed as threatening or sacred. The viewer’s ability to enjoy my pieces, regardless of their prior experience with the subject matter, is my priority. My primary means of creating my work is through drawing, with the end products taking the form of animations and zines. Sequential art provides a unique opportunity to form a relationship with the viewer during the short time they interact with the piece, which many drawings can’t accomplish in the same way. Zines and animations are highly shareable and exist as an experience as …

Annual Financial Report, Williamson County, Tennessee For The Year Ended June 30, 2020, Tennessee. Comptroller Of The Treasury.

Tennessee County Audit Reports

No abstract provided.

Representation Of The National Trauma In Train To Busan: Based On A Semiotic Approach, Junshik Shik Yun

Theses and Dissertations

The object of this project is to dissect the filmic elements in Train to Busan (2016) to analyze how the film represents the Sewol Ferry incident, a national disaster occurred in South Korea, and how the audience is able to engage with the trauma. As the first zombie blockbuster created in South Korea, Train to Busan adapted the elements of the zombie genre that has been delineated repeatedly. The film inherited the traits of zombies, representation of government and media, and feature of human characters from the genre created in Hollywood. Additionally, national characteristics had been added through reflecting the …

Lung Epithelial Trpa1 Mediates Lipopolysaccharide-Induced Lung Inflammation In Bronchial Epithelial Cells And Mice, Hsin-Kuo Ko, An-Hsuan Lin, Diahn-Warng Perng, Tzong-Shyuan Lee, Yu Ru Kou

Physiology Faculty Publications

Toll-like receptor (TLR) 4 was originally thought to be the sole pattern recognition receptor for lipopolysaccharide (LPS). Transient receptor potential ankyrin 1 (TRPA1), a Ca²⁺-permeant channel, has been suggested as a non-TLR receptor membrane-bound sensor of LPS. We recently reported that TRPA1 is expressed in lung epithelial cells (LECs) and mediates lung inflammation induced by cigarette smoke. However, the role of TRPA1 in LPS-induced lung inflammation has not been conclusively defined, and its underlying cellular mechanisms remain unclear. In this study, our in vitro results showed that LPS sequentially produced a cascade of events, including the elevation of …

Evidence For A Late Glacial Advance Near The Beginning Of The Younger Dryas In Western New York State: An Event Postdating The Record For Local Laurentide Ice Sheet Recession, Richard A. Young, Lee M. Gordon, Lewis A. Owen, Sebastien Huot, Timothy D. Zerfas

Geological Sciences

Widespread evidence of an unrecognized late glacial advance across preexisting moraines in western New York is confirmed by 40 ¹⁴C ages and six new optically stimulated luminescence analyses between the Genesee Valley and the Cattaraugus Creek basin of eastern Lake Erie. The Late Wisconsin chronology is relatively unconstrained by local dating of moraines between Pennsylvania and Lake Ontario. Few published ¹⁴C ages record discrete events, unlike evidence in the upper Great Lakes and New England. The new ¹⁴C ages from wood in glacial tills along Buttermilk Creek south of Springville, New York, and reevaluation of numerous ^{14 …}

How Expansile Is A Culture Of Cancel?, Jethro K. Lieberman

Other Publications

No abstract provided.

Air Pollution And The Dynamic Association Between Depressive Symptoms And Memory In Oldest-Old Women, Andrew J. Petkus, Diana Younan, Xinhui Wang, Daniel P. Beavers, Mark A. Espeland, Margaret Gatz, Tara Gruenewald, Joel D. Kaufman, Helena C. Chui, Joann E. Manson, Susan M. Resnick, Gregory A. Wellenius, Eric A. Whitsel, Keith Widaman, Jiu-Chiuan Chen

Psychology Faculty Articles and Research

BACKGROUND/OBJECTIVES

Exposure to air pollution may contribute to both increasing depressive symptoms and decreasing episodic memory in older adulthood, but few studies have examined this hypothesis in a longitudinal context. Accordingly, we examined the association between air pollution and changes in depressive symptoms (DS) and episodic memory (EM) and their interrelationship in oldest-old (aged 80 and older) women.

DESIGN

Prospective cohort data from the Women's Health Initiative Memory Study-Epidemiology of Cognitive Health Outcomes.

SETTING

Geographically diverse community-dwelling population.

PARTICIPANTS

A total of 1,583 dementia-free women aged 80 and older.

MEASUREMENTS

Women completed up to six annual memory assessments (latent composite …

Structure Of The Receptor Binding Domain Of Envp(B)1, An Endogenous Retroviral Envelope Protein Expressed In Human Tissues, Kevin R Mccarthy, Joseph L Timpona, Simon Jenni, Louis-Marie Bloyet, Vesna Brusic, Welkin E Johnson, Sean P J Whelan, Lindsey R Robinson-Mccarthy

Open Access Publications

EnvP(b)1 is an endogenous retroviral envelope gene found in human and other primate genomes. We report EnvP(b)1 sequences in primate genomes consistent with an integration event between 40 and 71 million years ago. Using a highly specific polyclonal antiserum raised against the putative receptor binding domain (RBD) of human EnvP(b)1, we detected expression in human placenta, ovaries, and thymus. We found that EnvP(b)1 is proteolytically processed, and using cell-cell fusion assays in multiple primate cell lines, we demonstrated that extant EnvP(b)1 proteins from a variety of primate genomes are fusogenic. This work supports the idea that EnvP(b)1 is under purifying …

Gastrointestinal Parasites In The Neotropical Otter (Lontra Longicaudis Annectens) In Central Mexico, Erika Y. Badillo Flores, Marcos G. Torres Tobón, C. Gustavo Aguilar Cabrera, O. Eric Ramírez-Bravo, Eva Romero Callejas

Western North American Naturalist

We analyzed 47 scats of neotropical otter (Lontra longicaudis annectens), collected along the Necaxa River in Central Mexico, using the Willis flotation technique with a 48% saturated saline solution. Along with plant material, we found the endoparasites Oxyuris equi, Ascaris sp., and Strongylus equinus, among others. Our results indicate that otters in the Necaxa River have a parasite load that needs further analysis, particularly because 2 of the parasite species are associated with human activity.


Analizamos 47 excretas de nutria neotropical (Lontra longicaudis annectens), colectadas a lo largo del Río Necaxa en el Centro …

Data-Driven Modeling Of The Causes And Effects Of Interneuronal Dysfunction In Alzheimer’S Disease And Dravet Syndrome, Carlos Perez

USF Tampa Graduate Theses and Dissertations

One of the defining features of Alzheimer’s disease (AD) is the increased cleavage of the amyloid precursor protein (APP), causing abnormally high levels of the aggregation form of amyloid beta (Aβ ). Many studies have shown that both AD patients and AD mice models exhibit abnormal network activity, including hypersynchronous excitatory neuron behavior, altered brain rhythms, and in some instances epileptic seizures when exposed to high levels of Aβ In particular, strong experimental evidence suggests that it is the small globular amyloid oligomers (gOs) and curvilinear fibrils (CFs) rather than the more stable, late stage rigid fibrils (RFs) that cause …

Coastline, Izze Gunn

.RAW Journal of Art and Design

No abstract provided.

Full Issue

.RAW Journal of Art and Design

No abstract provided.

Molecular Mechanisms Of Boron Toxicity Tolerance In Plants, Guannan Wang

LSU Doctoral Dissertations

Boron toxicity is a worldwide agricultural problem that limits crop productivity and quality. However, our understanding on the genetic responses and adaption mechanisms to boron toxicity in plants is very limited. To address this gap in our knowledge, I compared boron stress-sensitive model, Arabidopsis thaliana and its stress-adapted relative Schrenkiella parvula to study how plants respond and adapt to excess boron at physiological, genomic, transcriptomic, and metabolic levels.

The overall project goal involved integration of multi-omics datasets to develop genome to phenome interpretations. To achieve this, I developed a python package, GOMCL, to facilitate the extraction of biologically meaningful information …

Structure And Dynamics Of Phospholipid Vesicles And The Dependence On Nanoscale Interactions With Molecules Of Varying Complexity, Lakshapathy Widanelage Judith Upeka De Mel

LSU Doctoral Dissertations

In this dissertation, molecular interactions and changes imposed by nano-scale structures on phospholipid vesicles were investigated. 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) large unilamellar vesicles (LUVs) were used as the model system. Understanding changes of the bilayer structure, interfacial properties, lipid dynamics, and self-assembly, allows bridging relationships between biological cell membrane structure and dynamics to cellular functionalities. For example, membrane curvature changes are linked to membrane protein functions, although the exact mechanisms of control are not yet understood. Moreover, the knowledge gained from vesicle models allows exploring novel strategies for drug delivery applications. To achieve this, DOPC LUVs were synthesized and characterized by a …

Sexually Dimorphic Oxytocin Receptor-Expressing Neurons In The Anteroventral Periventricular Nucleus Regulates Maternal Behavior, Kaustubh Sharma

LSU Doctoral Dissertations

The neurohypophysial hormone oxytocin is involved in the regulation of social behaviors, including social recognition, pair bonding, and sex-specific parental behaviors in a variety of species. Oxytocin triggers these social behaviors by binding to oxytocin receptors (OXTR) in various parts of the brain. Oxytocin-induced sex-typical behavior, therefore, suggests a sexual dimorphic distribution of OXTR in the brain. In recent years, the oxytocin system in the brain received tremendous attention as a potential pharmacological target for treatment of many psychiatric disorders, such as anxiety, autism spectrum disorders, and even sex-specific psychiatric disorder like postpartum depression (PPD). An important problem and a …

Womb-Lease Contracts With Particular Reference To The Jordanian Law: Comparative Research, Enas Qutieshat, Ameen Alawatl

An-Najah University Journal for Research - B (Humanities)

The commodification of the womb has become increasingly popular in the 21st century whereby; women who are unable to conceive due to a variety of reasons become look for women who are willing for a specified amount of money, to lease her womb be used to bear the pregnancy of the other people. The commodification of the womb has raised various ethical and legal questions. Some are related to the rights of both the surrogate mothers and the biological parents of the child. Others are related to the legitimacyof the child that results from this process. This paper will focus …

Methods Of Teaching By Professors Of Mathematics In Jordanian Universities, Amany Sbaih

An-Najah University Journal for Research - B (Humanities)

This study aims at identifying mathematics teaching methods used by mathematics teachers at the universities of Jordan and the attitudes. To achieve the objective of the study, the analytical descriptive approach has been applied. A random sample has been chosen from the faculty members specialized in mathematics at the University of Jordan, Hashemite University, AL-Bayet University and Al-Balqa’ Applied University in Jordan; (48) teachers. Two measures have been developed for the purposes of this study; the first measure: aims at identifying the most common teaching methods, the second: aims at measuring the attitudesof the faculty members at the universities towards …