Digital Commons Network^™

Molecular Detection Of Intestinal Helminths And Protozoa Among Young Children In Dosso Region, Niger, Kristen Aiemjoy, Ahmed M. Arzika, Catherine Cook, Elodie Lebas, Nils Pilotte, Jessica R. Grant, Steven A. Williams, Thomas M. Lietman, Jeremy D. Keenan

Biological Sciences: Faculty Publications

Eukaryotic parasites are significant contributors to childhood illness in Niger. While helminthiases have received national attention through mass deworming efforts, the epidemiology of intestinal protozoa in Niger remains underexamined. This study employed real-time PCR diagnostics to describe the prevalence of two schistosomes, four soil-transmitted helminths, and one protozoan parasite in Boboye Department, Dosso Region. Prevalence was assessed using bulk stool specimens collected from a population-based sample of 86 children residing in 9 communities. Anthropometric measurements were used to calculate child growth z-scores and stool consistency was graded. Helminths were absent from the study population, with the exception of a single …

Misconceptions About Conception And Other Fallacies: Historical Bias In Reproductive Biology, Virginia Hayssen

Biological Sciences: Faculty Publications

Natural selection (differential reproduction) is a major tenet of evolutionary theory. In mammals the success of reproduction is primarily controlled by females who provide the majority of offspring care via gestation and lactation. In some species, maternal care also extends post-weaning. This primacy of female reproduction in evolution has not quite crept into our understanding of organismal adaptations in anatomy, physiology, and behavior. This cultural legacy has left its mark and led to misconceptions in our understanding of reproductive biology that are especially prominent in the understanding of reproduction in the general public. Here, I give examples of such misconceptions. …

Corporations Hybrid: A Covid Case Study On Innovation In Business Law Pedagogy, Seth C. Oranburg, David D. Tamasy

Law Faculty Publications

This Article is about using "asynchronous" online technology synergistically with in-class experiences and "synchronous" livedistance education sessions. It focuses on creating instructional videos because great videos are essential for online learning.¹ This Article also discusses creating digital teaching assets for active learning such as formative assessments, learning journals, and discussion boards.

The authors of this paper are a law professor and his former student and teaching assistant. We worked together for two years to innovate and implement many technological enhancements in Corporations class. We created and deployed a "Hybrid" course in which students performed "asynchronous" technology-mediated learning activities before …

Substance Use Disorder Policy For Certified Registered Nurse Anesthetists: A Policy Analysis, Justin D. Mcadoo

Doctor of Nursing Practice Projects

Substance use disorders (SUDs) negatively impact society and communities while causing substantial harm to families and friends. The leading occupational hazard for Certified Registered Nurse Anesthetists (CRNAs) is SUDs. It is estimated that 15% of actively practicing CRNAs in the United States will have a SUD during their career. In order to address SUDs related to CRNAs in the workplace, anesthesia groups and healthcare facilities must develop, implement, and evaluate policies and procedures based on the translation of evidence-based research into the practice of anesthesia. This Doctor of Nursing Practice (DNP) project analyzed LifeLinc Anesthesia’s SUD policy for CRNAs, compared …

Cmn 4755 : Television Genres: Production & Development, Communication And Journalism

Approved Course Proposals

No abstract provided.

Correlation Of Serum Fatty Acid Binding Protein-4 And Interleukin-6 With Airflowlimitation And Quality Of Life In Stable And Acute Exacerbation Of Copd, Mohammad Reza Aslani, Zeynab Ghazaei, Hassan Ghobadi

Turkish Journal of Medical Sciences

Background/aim: The serum fatty acid binding protein 4 (FABP-4) level increases in chronic inflammatory diseases. The present study aimed to examine serum FABP-4 and interleukin (IL)-6 levels in patients with stable and acute exacerbation of chronic obstructive pulmonary disease (COPD) and the correlation of these markers with airflow limitation. Materials and methods: We measured serum FABP-4 and IL-6 levels in 60 COPD patients [30 stable COPD (SCOPD), and 30 acute exacerbation of COPD (AECOPD)], and 30 healthy subjects and compared them with airflow limitation according to the COPD stage in the Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) criteria, …

Effect Of Metformin And Detorsion Treatment On Serum Anti-Müllerian Hormonelevels And Ovarian Histopathology In A Rat Ovarian Torsion Model, Sema Karakaş, Ci̇han Kaya, Hakan Güraslan, Damlanur Sakiz, Sema Süzen Çaypinar, Hüseyi̇n Cengi̇z, Murat Eki̇n, Levent Yaşar

Turkish Journal of Medical Sciences

Background/aim: Adnexal torsion is a common gynaecological emergency, and considered to be a problem mostly in reproductive-age women. To evaluate the effect of metformin and detorsion treatment on reducing ovarian reserve in an ovarian torsion model. Materials and methods: Twenty-four nonpregnant, Wistar Hannover rats were included in the study. Animals were divided into 3 groups: the control group, the detorsion only group, and the metformin + detorsion group. The first group received only laparotomy. In the second group, ovaries were fixed to the abdominal wall after performing 360° ovarian torsion, followed by detorsion after a 3-h period of ischemia. The …

Horse Allergen Sensitivity And Respiratory Symptoms Among Horse Farm Workers, Burcu Baran Ketenci̇oğlu, İnsu Yilmaz, Nuri̇ Tutar, İnci̇ Gülmez, Fatma Sema Oymak

Turkish Journal of Medical Sciences

Background/aim: Sensitivity and symptoms related to animal proteins have been investigated in various occupational groups. However, data from horse farm workers are limited. We aimed to determine horse allergen sensitivity in the horse farm workers, and to evaluate its relationship with respiratory symptoms and functional parameters. Materials and methods: A total of 110 subjects were enrolled in the study. The study group consisted of 80 horse farm workers. Face-to-face surveys, skin prick tests (SPT), and pulmonary function tests (PFT) were performed in the study group. Control group consisted of 30 healthy subjects. SPT and PFTs were also performed for control …

Dti-Mri Findings In Synthetic Cannabinoid Users, Fatma Di̇lek Gökharman, Sonay Aydin, Sali̇h Ci̇hat Paltun, Erdem Fati̇hoğlu, Şafak Yalçin Şahi̇ner, Pinar Nerci̇s Koşar

Turkish Journal of Medical Sciences

Background/aim: Synthetic cannabinoids (SCs) are full agonists of both cannabinoid receptors. Conventional magnetic resonance imaging (MRI) findings of SC users are mainly defined as diffusion restriction and T2/FLAIR hyperintensity. Diffusion tensor imaging (DTI) studies examining SC users have shown contradictory results. The aim of this study was to define white matter (WM) changes of SC users using DTI. Materials and methods: The study included 22 patients with a history of using SC for 5-37 months, and 22 healthy, age and sex- matched control subjects. A total of 41 diffusion gradient directions were used in the acquisition of diffusion imaging data. …

Roles Of Glycoprotein Glycosylation In The Pathogenesis Of An Endemic Osteoarthritis, Kashin-Beck Disease, And Effectiveness Evaluation Of Sodium Hyaluronate Treatment, Sen Wang, Zongqiang Gao, Huan Liu, Peilin Meng, Cuiyan Wu, Mikko Lammi, Xiong Guo

Turkish Journal of Medical Sciences

Background/aim: We aimed to explore the roles of glycoprotein glycosylation in the pathogenesis of Kashin-Beck disease (KBD), and evaluated the effectiveness of sodium hyaluronate treatment. Materials and methods: Blood and saliva were collected from KBD patients before and after the injection of sodium hyaluronate. Normal healthy subjects were included as controls. Saliva and serum lectin microarrays and saliva and serum microarray verifications were used to screen and confirm the differences in lectin levels among the three groups. Results: In saliva lectin microarray, bindings to Sophora japonica agglutinin (SJA), Griffonia (Bandeiraea) simplicifolia lectin I (GSL-I), Euonymus europaeus lectin (EEL), Maackia amurensis …

The Disappearing Public Toilet, Taunya Lovell Banks

Seton Hall Law Review

No abstract provided.

Alterations In Follicular Fluid Bmp-15 Rna Expression In Women Undergoing Controlled Ovarian Hyperstimulation, Şükri̇ye Derya Deveci̇

Turkish Journal of Medical Sciences

Background/aim: Bone morphogenetic protein-15 (BMP-15) is one of the maturation indicators of the ovarian follicular pool. The aim of this study was to investigate the possible difference of follicular fluid (FF) BMP-15 RNA expression among low, normal, and high responder women attending controlled ovarian hyperstimulation-intracytoplasmic sperm injection (COH-ICSI) cycles.Materials and methods: This cross-sectional study was conducted with 75 FFs of COH-ICSI cycles performed at the IVF Unit of University Hospital. Twenty FF from low response (group 1), 27 FF from normal response (group 2), and 28 FF from high response (group 3) were recruited for the study between September 2014 …

What Is The Impact Of Ppar-? Agonist-Rosiglitazone On Ovarian Reserve After Hysterectomy? An Experimental Study, Burcu Gündoğdu Öztürk, Ömer Lütfi̇ Tapisiz, Berna Di̇lbaz, Serkan Bariş Mülazimoğlu, Kami̇l Hakan Müftüoğlu, Betül Dündar, Ümi̇t Göktolga

Turkish Journal of Medical Sciences

Background/aim: To evaluate the effects of hysterectomy on rat ovaries and the possible protective role of peroxisome proliferator-activated receptor gamma (PPAR-?) agonist-rosiglitazone against ovarian reserve decrement.Materials and methods: Forty-five adult Wistar albino rats were randomly divided into three groups. Hysterectomy was performed (n = 15) in group 1 [H]; 1 mg/kg/day PPAR-? agonist/rosiglitazone was used for 50 days after hysterectomy (n = 15) in group 2 [H + R]; a sham operation was performed (n = 15) in group 3 [control, C]. Blood samples were collected for anti-Müllerian hormone (AMH) evaluation in all groups and simultaneous ovarian Doppler examination was …

A Study Of Drynariafortunei In Modulation Of Bmp-2 Signalling By Bone Tissue Engineering, Guo-Chung Dong, Tzn-Yuan Ma, Chi-Han Li, Chih-Ying Chi, Chao-Ming Su, Chih-Ling Huang, Yan-Hsiung Wang, Tzer-Ming Lee

Turkish Journal of Medical Sciences

Background/aim: Drynaria fortunei (Gusuibu; GSB) is a popular traditional Chinese medicine used for bone repair. An increasing number of studies have reported that GSB induces osteogenic differentiation in bone marrow mesenchymal stem cells (BMSCs). These results provide insight into the application of GSB for bone tissue engineering techniques used to repair large bone defects. However, few studies have described the molecular mechanisms of GSB.Materials and methods: In the present study, the effects of GSB and naringin, a marker compound, on the binding of BMP-2 to BMPR and BMP-2-derived signal transduction were investigated using surface plasmon resonance (SPR) and coculturing with …

Surface Enhanced Raman Spectroscopy As A Novel Tool For Rapid Quantification Of Heroin And Metabolites In Saliva, Ramazan Akçan, Mahmut Şeri̇f Yildirim, Hasan İlhan, Burcu Güven, Uğur Tamer, Necdet Sağlam

Turkish Journal of Medical Sciences

Background: Heroin can be detected and quantified by certain analytical methods, however, forensic professionals and criminal laboratories study for cheaper and faster detection tools. Surface-enhanced Raman spectroscopy (SERS) rises as a possible alternative tool with its widening application spectra. There are few studies regarding Raman and SERS spectra of heroin and its metabolites, which are unfortunately controversial. In this study, we compared five different surfaces in order to find out more efficient Raman-active substrate for opiate detection and rapid quantification of heroin and its metabolites in saliva.Materials and methods: Morphine standard material was used to identify proper surface for SERS …

Posthepatectomy Liver Failure, İlhan Ocak, Serdar Topaloğlu, Koray Acarli

Turkish Journal of Medical Sciences

Liver surgery is one of the most complex surgical interventions with high risk and potential for complications. Posthepatectomy liver failure (PHLF) is a serious complication of liver surgery that occurs in about 10% of patients undergoing major liver surgery. It is the main source of morbidity and mortality. Appropriate surgical techniques and intensive care management are important in preventing PHLF. Early start of the liver support systems is very important for the PHLF patient to recover, survive, or be ready for a liver transplant. Nonbiological and biological liver support systems should be used in PHLF to prepare for treatment or …

Melatonin, Aging, And Covid-19: Could Melatonin Be Beneficial For Covid-19 Treatment In The Elderly?, Güler Öztürk, Kazi̇me Gonca Akbulut, Şevi̇n Güney

Turkish Journal of Medical Sciences

The aim of this review is to summarize current studies on the relationship between melatonin and aging. Nowadays, age-related diseases come into prominence, and identifying age-related changes and developing proper therapeutic approaches are counted as some of the major issues regarding community health. Melatonin is the main hormone of the pineal gland. Melatonin is known to influence many biological processes in the body, including circadian rhythms, the immune system, and neuroendocrine and cardiovascular functions. Melatonin rhythms also reflect the biological process of aging. Aging is an extremely complex and multifactorial process. Melatonin levels decline considerably with aging and its decline …

Does The Volume Overload Exaggerate The Severity Of Mitral Regurgitation In Patients With Decompensated Heart Failure?, Göktuğ Savaş, Ömer Şahi̇n, Mustafa Yaşan, Uğur Karabiyik, Ni̇hat Kalay, Ali̇ Doğan, Ferhan Elmali, Abdurrahman Oğuzhan

Turkish Journal of Medical Sciences

Background/aim: Diagnosing and managing functional mitral regurgitation (MR) is often challenging and requires an integrated approach including a comprehensive echocardiographic examination. However, the effects of volume overload on the echocardiographic assessment of MR severity are uncertain. The purpose of this study was to weigh the effects of volume overload in the echocardiographic assessment of MR severity among patients with heart failure (HF). Materials and methods: Twenty-nine patients with decompensated HF, who had moderate or severe MR, were included in the present study. The volume status and the N-terminal pro-B-type natriuretic peptide (proBNP) levels were recorded and the echocardiographic parameters were …

Effects Of Acute Hypoxia On Auditory Pathway Of Wistar Albino Rats, Nevreste Di̇dem Sonbay Yilmaz, Cem Saka, Si̇bel Ali̇cura Tokgöz, Murat Çalişkan, Erkan Vuralkan, Ömer Beşalti

Turkish Journal of Medical Sciences

Background/aim: Ischemia is insufficient blood flow to provide adequate oxygenation. In the present study, we aimed to show whether acute hypoxia has a critical oxygen value that may lead to the deterioration of cochlear function. Materials and methods: Under general anesthesia, prehypoxic signal-to-noise ratios were determined by distortion product otoacoustic emissions (DPOAE). The oxygen saturation (SaO2) values of rats were monitored with an oxygen saturation probe. Rats were injected with an extra dose of anesthetic agent, and SaO2 was reduced. DPOAE values in SaO2 100?90, 90?80, 80?70, and 70?60 posthypoxic values were measured and compared statistically with prehypoxic values. Results: …

Anakinra, An Interleukin-1 Receptor Antagonist, Increases The Morphine Analgesic Effectand Decreases Morphine Tolerance Development By Modulating Oxidative Stress Andendoplasmic Reticulum Stress In Rats, Onur Avci, Ahmet Şevki̇ Taşkiran

Turkish Journal of Medical Sciences

Background/aim: Recent studies have shown that inflammation plays a role in morphine analgesia and tolerance development. Anakinra is a competitive inhibitor of IL-1 receptors and an antiinflammatory protein regulating IL-1ß's biological activity by avoiding signal transduction. In this study, we aimed to examine the effects of anakinra on morphine analgesia and tolerance. Materials and methods: In this study, 36 Wistar Albino (230-250 g) male rats were used. Animals were divided into 6 groups: saline (S), 100 mg/kg anakinra (A), 5mg/kg morphine (M), M+A, morphine tolerance (MT), and MT+A. The resulting analgesic effect was measured with hot plate and tail-flick analgesia …

Antiviral Treatment Of Covid-19, Serap Yavuz, Serhat Ünal

Turkish Journal of Medical Sciences

Currently, there is not any specific effective antiviral treatment for COVID-19. Although most of the COVID-19 patients have mild or moderate courses, up to 5%-10% can have severe, potentially life threatening course, there is an urgent need for effective drugs. Optimized supportive care remains the mainstay of therapy. There have been more than 300 clinical trials going on, various antiviral and immunomodulating agents are in various stages of evaluation for COVID-19 in those trials and some of them will be published in the next couple of months. Despite the urgent need to find an effective antiviral treatment for COVID-19 through …

Immune Gene Therapy Of Cancer, Hakan Akbulut

Turkish Journal of Medical Sciences

Cancer gene therapy emerged as a promising treatment modality 3 decades ago. However, the failure of the first gene therapy trials in cancer treatment has decreased its popularity. Likewise, immunotherapy has followed a similar course. While it was a popular and promising treatment with IL-2 and interferon and cancer vaccines in the 1980s, it later lost its popularity. Immunotherapy became one of the main options for cancer treatment with the successful use of immune checkpoint inhibitors in clinics approximately 10 years ago. The success of immunotherapy has increased even more with the introduction of cancer gene therapy methods in this …

Yes, School Librarians Teach Reading: Reading Skill Reinforcement And The School Librarian, Tammy S. Gruer, Karen M. Perry

STEMPS Faculty Publications

The article discusses that school librarians are the literacy leaders in their buildings. It mentions that reinforcing reading skills taught in the classroom and motivating students to practice reading are an integral part of a school librarian's job; and also mentions that reading aloud to students from chapter books helps develop their imagination.

The Ethicality Of Point-Of-Sale Marketing Campaigns: Normative Ethics Applied To Cause-Related Checkout Charities, Johnette (Jay) Caulfield, Catharyn Baird, Felissa K. Lee

Management Faculty Research and Publications

“Would you like to contribute to XYZ charity by adding a dollar to your bill today?” Point-of-sale campaigns for fundraising are common to grocery stores, pharmacies, restaurants and warehouse clubs. Commonly referred to as ‘checkout charity,’ these fundraisers have generated over $4.1 billion in contributions for nonprofits over the past three decades. Yet little research has focused on the ethicality of this type of campaign. To address this need, we analyze the issue using behavioral ethics (moral identity and emotional triggers of behavior) and normative theory (consequentialism, deontology, and virtue ethics). We consider three stakeholder perspectives, including the nonprofit initiating …

Extraction Of Vehicle Can Bus Data For Roadway Condition Monitoring, Howell Li, Enrique Saldivar-Carranza, Jijo K. Mathew, Woosung Kim, Jairaj Desai, Timothy Wells, Darcy M. Bullock

JTRP Technical Reports

Obtaining timely information across the state roadway network is important for monitoring the condition of the roads and operating characteristics of traffic. One of the most significant challenges in winter roadway maintenance is identifying emerging or deteriorating conditions before significant crashes occur. For instance, almost all modern vehicles have accelerometers, anti-lock brake (ABS) and traction control systems. This data can be read from the Controller Area Network (CAN) of the vehicle, and combined with GPS coordinates and cellular connectivity, can provide valuable on-the-ground sampling of vehicle dynamics at the onset of a storm. We are rapidly entering an era where …

Out To Save The World: The Intersection Of Animal Welfare Law, Environmental Law, And Respect For Fragile Ecosystems, Stacey L. Gordon

Faculty Law Review Articles

Of all the living things on earth, humans have the unique ability to destroy all life. Paradoxically, even though our lives will ultimately be destroyed too, we also seem to have the inability to stop the destruction, or at least alack of will to stop it. As the daily litany of new destructions² piles up and both the pace and the quantity increase, each loss is buried in the pile beneath humanity’s other problems. When humans start prioritizing, the living environment—both flora and fauna—is often neglected, and sometimes purposely harmed.³ Even nonliving elements of nature are harmed. In …

Spring 2020_95.2_Full Issue

New Mexico Historical Review

No abstract provided.

Francisco Ramírez De Salazar And The Sobaipuris, John P. Wilson, Rick Hendricks

New Mexico Historical Review

No abstract provided.

Lexical Items As Facets Of Identity In Discourse, Joseph C. M. Davis

Publications and Research

Lexical items are used in discourse not to provide objective direct reference, nor to reflect a language’s system of categorization, nor in accordance with cognitive categories, but rather to communicate different perspectives. Lexical items function as facets of identity, chosen by an author to convey a subjective message. The point is illustrated through an analysis of lexical co-reference in Antonio Tabucchi’s Donna di Porto Pim e altre storie.

The Effect Of Long-Term Stress On Hippocampus And The Involvement In The Pathophysiology Of Psychological Disorders, Suicide, And Alcohol Use Disorder, Hinza Batool Malik

Undergraduate Research Awards

The hyperactivity of the HPA axis due to long-term stress results in an abnormally high level of glucocorticoids. A limbic system structure, the hippocampus has the highest number of receptor sites for glucocorticoids. Thus, making it highly vulnerable to damage during elevated levels of glucocorticoids, through neurotoxicity and metabolic challenges. In addition, this paper largely focuses on the effects of stress on the hippocampus, e.g., changes in hippocampal volume, as a contributing factor in the psychophysiology of a myriad of mental health problems. Most disorders follow the diathesis-stress trajectory where the symptoms begin to precipitate once a major stressor is …