Digital Commons Network^™

Model Organism Development And Evaluation For Late-Onset Alzheimer's Disease: Model-Ad., Adrian L Oblak, Stefania Forner, Paul R Territo, Michael Sasner, Gregory W. Carter, Gareth R Howell, Stacey J Sukoff-Rizzo, Benjamin A Logsdon, Lara M Mangravite, Ali Mortazavi, David Baglietto-Vargas, Kim N Green, Grant R Macgregor, Marcelo A Wood, Andrea J Tenner, Frank M Laferla, Bruce T Lamb, The Model-Ad Consortium

Faculty Research 2020

Alzheimer's disease (AD) is a major cause of dementia, disability, and death in the elderly. Despite recent advances in our understanding of the basic biological mechanisms underlying AD, we do not know how to prevent it, nor do we have an approved disease-modifying intervention. Both are essential to slow or stop the growth in dementia prevalence. While our current animal models of AD have provided novel insights into AD disease mechanisms, thus far, they have not been successfully used to predict the effectiveness of therapies that have moved into AD clinical trials. The Model Organism Development and Evaluation for Late-onset …

Initial Validation Of Proton Dose Calculations On Spr Images From Dect In Treatment Planning System, Pouya Sabouri

All Publications

No abstract provided.

Crow's Nest, November 23, 2020, Crow's Nest Staff

Crow's Nest

The November 23, 2020, issue of the Crow's Nest.

Episode 5: Milagro Truyol Quiroz, Christina Torres

Futures in Languages Transcripts

Listen to Milagro talk about her experiences studying in the Spanish BA, Spanish MA, and MATESOL programs. You'll also hear about her professional experiences working as an instructor.

[Silk Snapper, Lutjanus Vivanus] Neurocranium, Rachel Taylor, David W. Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Silk snapper, Lutjanus vivanus, apart of the Lutjanidae family. A species of red snapper commonly found in the Atlantic and Gulf of Mexico.

Neurocranium prep submission for Dr. Kertstetter, MBIO 3700 Biology of Fishes

The Guardian, Week Of November 23, 2020, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the week of November 23, 2020. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.

Student Life E-Newsletter November 23, 2020, Seattle University School Of Law Student Life

Student Life E-Newsletters

No abstract provided.

Sleep Deprivation And Neurological Disorders, Muhammed Bishir

Brain and Mind Institute

Sleep plays an important role in maintaining neuronal circuitry, signalling and helps maintain overall health and wellbeing. Sleep deprivation (SD) disturbs the circadian physiology and exerts a negative impact on brain and behavioural functions. SD impairs the cellular clearance of misfolded neurotoxin proteins like α-synuclein, amyloid-β, and tau which are involved in major neurodegenerative diseases like Alzheimer’s disease and Parkinson’s disease. In addition, SD is also shown to affect the glymphatic system, a glial-dependent metabolic waste clearance pathway, causing accumulation of misfolded faulty proteins in synaptic compartments resulting in cognitive decline. Also, SD affects the immunological and …

Two New Species Of Tardigrada From Moss Cushions (Grimmia Sp.) In A Xerothermic Habitat In Northeast Tennessee (Usa, North America), With The First Identification Of Males In The Genus Viridiscus, Diane R. Nelson, Rebecca Adkins Fletcher, Roberto Guidetti, Milena Roszkowska, Daria Grobys, Lukasz Kaczmarek

ETSU Faculty Works

Background. The phylum Tardigrada consists of over 1,300 species that inhabit terrestrial, freshwater and marine environments throughout the world. In terrestrial habitats they live primarily in mosses, lichens, leaf litter and soil, whereas tardigrades in freshwater and marine environments are mainly found in sediments and on aquatic plants. More than 65 species have been previously reported in the state of Tennessee, USA. Methods. Tardigrades present in moss cushions (Grimmia sp.) collected from a xerothermic habitat on the East Tennessee State University campus, Johnson City, TN, USA, were extracted, mounted on slides, identified, and counted. Additional samples of fresh dried moss …

The Bg News November 23, 2020, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. November 23, 2020. Volume 100-Issue 15.

Territorial And Extraterritorial Trigeminocardiac Reflex: A Review For The Neurosurgeon And A Type Iv Reflex Vignette, Fidias Leon-Sarmiento

All Publications

The trigeminocardiac reflex (TCR) is a complex and, sometimes, fatal event triggered by overstimulation of the trigeminal nerve (TN) and its territorial and spinal cord branches. We reviewed and compiled for the neurosurgeon key aspects of the TCR that include a novel and straightforward classification, as well as morphophysiology, pathophysiology, neuromonitoring and neuromodulation features. Further, we present intraoperative data from a patient who developed extraterritorial, or type IV, TCR while undergoing a cervical surgery. TCR complexity, severity and unwanted outcomes indicate that this event should not be underestimated or overlooked in the surgical room. Timely TCR recognition in surgical settings …

Interview With Kristina Wong, Kristina Wong

Auntie Sewing Squad Interviews

Kristina Wong is a third generation Chinese American who was born and raised in San Francisco, California. Kristina’s profession consists from being a performance artist to an actor. Kristina is the creator of the Auntie Sewing Squad. This organization involves individuals sewing masks from their homes and sending these masks to those in need.

Linking Mosquito Surveillance To Dengue Fever Through Bayesian Mechanistic Modeling, Clinton B. Leach, Jennifer A. Hoeting, Kim M. Pepin, Alvaro E. Eiras, Mevin B. Hooten, Colleen T. Webb

United States Department of Agriculture Wildlife Services: Staff Publications

Our ability to effectively prevent the transmission of the dengue virus through targeted control of its vector, Aedes aegypti, depends critically on our understanding of the link between mosquito abundance and human disease risk. Mosquito and clinical surveillance data are widely collected, but linking them requires a modeling framework that accounts for the complex non-linear mechanisms involved in transmission. Most critical are the bottleneck in transmission imposed by mosquito lifespan relative to the virus’ extrinsic incubation period, and the dynamics of human immunity. We developed a differential equation model of dengue transmission and embedded it in a Bayesian hierarchical …

State V. Fitzpatrick Appellant's Brief Dckt. 47818

Not Reported

No abstract provided.

Covid-19: Best Practices And The Way Forward, Juliana Nwauwa

Student Scholarly Projects

COVID-19 is a global health emergency that originated in Wuhan, China, in December 2019. It was declared a pandemic on March 11, 2020, and since then has affected more than 53,507,282 individuals and claimed the lives of more than 1,305,164 around the globe. It is a respiratory virus transmitted from person to person through airborne aerosols and droplets from infected individuals and direct contact with infected surfaces.

Numerous factors, such as socioeconomic status, population density, pre-existing health conditions, and lack of health insurance, have contributed to the disproportionate impact of COVID-19 among certain demographic groups. The COVID-19 impact ranges from …

Central Nervous System Pathology In Preclinical Mps Iiib Dogs Reveals Progressive Changes In Clinically Relevant Brain Regions, Martin T Egeland, Marta M Tarczyluk-Wells, Melissa M Asmar, Evan G Adintori, Roger Lawrence, Elizabeth M Snella, Jackie K Jens, Brett E Crawford, Jill C M Wait, Emma Mccullagh, Jason Pinkstaff, Jonathan D Cooper, N Matthew Ellinwood

2020-Current year OA Pubs

Mucopolysaccharidosis type IIIB (MPS IIIB; Sanfilippo syndrome B) is an autosomal recessive lysosomal storage disorder caused by the deficiency of alpha-N-acetylglucosaminidase activity, leading to increased levels of nondegraded heparan sulfate (HS). A mouse model has been useful to evaluate novel treatments for MPS IIIB, but has limitations. In this study, we evaluated the naturally occurring canine model of MPS IIIB for the onset and progression of biochemical and neuropathological changes during the preclinical stages (onset approximately 24-30 months of age) of canine MPS IIIB disease. Even by 1 month of age, MPS IIIB dogs had elevated HS levels in brain …

Livestock Diversity And Climate Change In Rangelands, Irene Hoffmann, Beate Scherf, David Boerma

IGC Proceedings (1977-2023)

No abstract provided.

The Effect Of Climate Change On Livestock Carrying Capacity Of Inner Mongolia, Yurong Wei, Ruiqing Guo, Xuebiao Pan, Buju Long

IGC Proceedings (1977-2023)

No abstract provided.

The Utilization Of Flashcards In Children Information Literacy Development, Dessy Harisanty, Dyah Srirahayu, Tiara Kusumaningtiyas, Esti Anugrah, Islahun Permata, Dian Anggraeni

Library Philosophy and Practice (e-journal)

A Flashcard is one of the media to develop student information literacy in which its application includes activities of analyzing, writing and telling stories. Storytelling is a process of reading that is useful to increase the courage to appear in public. This research used descriptive method. For preliminary research, we used experiments, making flash cards as learning media for elementary students. After that, the students were interviewed. The results of this study indicate that students are very enthusiastic to start a flashcard game that they think is fun. The benefits of a flashcard game include improving language skills, increasing the …

The Effect Of Teaching Mathematics Using Interactive Video Games On The Fifth Grade Students' Achievement, Bassam Ibrahim, Yaser Abu Hmaid

An-Najah University Journal for Research - B (Humanities)

The aim of this study is to investigate the effect of teaching math subject using interactive video games on the fifth grade students ’achievement. This study was conducted in one basic private school in Jordan. It used a quasi- experimental control group design. Interactive video games software was developed to investigate the difference between the two groups that were given a pre-test and a post-test to measure their achievements in math. The results of the study showed that the learning environment in math using interactive video games have a positive effect on fifth grade students' math achievements. The study showed …

Spatial Pattern And Uncertainty Of Soil Organic Carbon And Implications For Sampling Design, Feng Liu, Xinyuan Ben Wu, E. Bai, Thomas W. Boutton, Steven R. Archer

IGC Proceedings (1977-2023)

No abstract provided.

Honors Students Hold Annual Enchanted Forest Event, Claire Allen

GWU-Today

This November, the Honors Student Association held their annual “The Enchanted Forest” event at the Broad River Greenway in Boiling Springs. Many look forward to the opportunity where members, the majority of whom were freshmen and first year students, gathered to provide a fun and educational experience to children. The project took place over the course of two evenings, Friday, Nov. 6, and Saturday, Nov. 7.

Happy Thanksgiving! And Hail To The Pharmaceutical And Biotech Industries – And The Scientists!, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.

Eco-Critique And Thought As A Force Of Nature, Stephanie Erev

Political Science Faculty Publications and Presentations

It occurred to me not long ago that each time I read something new I pay special attention, without really meaning to, to how the work projects forward into a future or futures. This has been going on, I now think, for some years. Perhaps this quasi-conscious reading practice has played a part in the recalibration of my own orientations to the future, which, with every new climatic event, seem to grow dizzier and more disorganized, feeling some of the time like players in a game of musical chairs. Whether it is in relation to “All Around the Mulberry Bush” …

A Scientometric Profile Of Dibrugarh University, Dibrugarh (Assam) Through The Lens Of Web Of Science, During 1989-2020, Pranjal Deka

Library Philosophy and Practice (e-journal)

Dibrugarh University(DU) is a leading higher educational institution in NE India. It has a significant impact on research and development. This study covers the research productivity of the university from 1989-2020 through the Web of Science Database. The study reveals that research publications of the university are growing day by day in different dimensions. The year 2019 is the most productive year of the university. The department of chemistry is a significant department for research productivity. The university has proper international and intranational coordination among various institutions and researchers.

Factory Farming: Polluting The Environment By Supplying One Mcdonald’S At A Time, Gillian Fletcher

Biology Student Scholarship

A modern practice that has a negative impact on the environment that many take part in everyday without even knowing, is ‘factory farming’. ‘Factory farming’ is the practice of large-scale production of livestock or crops that are used to compensate for the exponentially growing population and the demand for ready-made meals at a low cost. This paper examines the reason for the transition from sustainable agriculture to factory farming, its environmental impacts, and what corporations are benefitting at the expense of the environment. Explanations are given to support the abolishment of such harmful and unethical practices like ‘factory farming’ in …

Statin Treatment In Specific Patient Groups: Role For Improved Cardiovascular Risk Markers, Alyssa White, Hillary R. Mishcon, John L. Redwanski, Ronald D. Hills Jr

Pharmaceutical Sciences Faculty Publications

Ample evidence supports the use of statin therapy for secondary prevention in patients with a history of atherosclerotic cardiovascular disease (ASCVD), but evidence is wanting in the case of primary prevention, low-risk individuals, and elderly adults 65+. Statins are effective in lowering low-density lipoprotein (LDL), which has long been a target for treatment decisions. We discuss the weakening dependence between cholesterol levels and mortality as a function of age and highlight recent findings on lipoprotein subfractions and other superior markers of ASCVD risk. The efficacy of statins is compared for distinct subsets of patients based on age, diabetes, ASCVD, and …

Examining The U.S. Wars On Vietnam, Laos, And Cambodia As The Production Of Neo-Colonialism, Aiden Gregg

University Honors Theses

I interrogate the colonial and neo-colonial histories of the U.S. wars on Vietnam, Cambodia, and Laos within the context of racialized and gendered labor accumulation, the production of difference through violence as a legitimation of colonial extraction, and ongoing neoliberal economic coercion. I examine genocide and ecocide as interdependent processes in the production of dependency and underdevelopment. I reject a common narrative of temporal and spatial disconnection which separates the wars from current economics and examine the violences which both produce and result from an economy based on growth.

Grim Under A Compensation Variant, Aaron Davis, Aaron Davis

Honors College Theses

Games on graphs are a well studied subset of combinatorial games. Balance and strategies for winning are often looked at in these games. One such combinatorial graph game is Grim. Many of the winning strategies of Grim are already known. We note that many of these winning strategies are only available to the first player. Hoping to develop a fairer Grim, we look at Grim played under a slighlty different rule set. We develop winning strategies and known outcomes for this altered Grim. Throughout, we discuss whether our altered Grim is a fairer game then the original.

Mapping Of Microbial Technology Research Output At The Global Level: A Scientometric Study, P. Ashok Kumar Dr., R. Manoranjitham Dr., K. Sivasekaran Dr.

Library Philosophy and Practice (e-journal)

Using the Web of Science Bibliographic database, the present study tries to give a complete view of the evolution of the field of Microbial technology research output during the period from 1990 to 2018. The study presents the growth tendency and literature output in the field of Microbial Technology. The study shows that a total of 2968 articles were published during the period by the top authorship pattern, collaborative coefficient, doubling time key word co-occurrence, co-authorship pattern etc.,. some of those research articles have been produced by single authors while multiple authors have contributed articles in most other instances,