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2020

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Characterization Of Bison Finishing And Harvest Systems: Effects On Carcass And Meat Quality Characteristics, Jessica Janssen Jan 2020

Characterization Of Bison Finishing And Harvest Systems: Effects On Carcass And Meat Quality Characteristics, Jessica Janssen

Electronic Theses and Dissertations

The objectives of this thesis project were to 1) characterize the influence of finishing system (grain-finished vs. grass-finished) on carcass characteristics, meat quality, the nutritional composition, and consumer preference for bison meat 2) evaluate the effectiveness of beef camera grading technology on grain- and grass-finished bison carcass characteristics, and 3) characterize the influence harvest systems (on-ranch vs. commercial facilities) on animal stress response, carcass characteristics, meat quality, and consumer preference of bison heifers. For objectives 1 and 2: Grain- (n=108) and grass- (n=93) finished bison heifers were slaughtered at 28 mo of age, at approximately 20 h postmortem, carcass measurements …


Modification Of Plant Proteins And Their Potential Application As Fish Meal Replacements In Rainbow Trout Oncorhynchus Mykiss Feeds, Miran Jaza Hama Salh Jan 2020

Modification Of Plant Proteins And Their Potential Application As Fish Meal Replacements In Rainbow Trout Oncorhynchus Mykiss Feeds, Miran Jaza Hama Salh

Electronic Theses and Dissertations

Soybean meals (SBM) and its by-products are the most common plant feedstuffs that are used in feeds for a variety of fish species of fish over the last three decades due to high protein levels and good amino acid profile, in comparison with other plant protein sources. In the last two decades the production of soybean was around zero metric tons (Index, 2020). Barley is another plant protein that has been tested in some species diets. While barley is used in many areas such as brewing industry, animal feeding, human consumption, it is mainly used for animal feeding in Kurdistan. …


Impact Of Altering Lys : Energy Ratio During Gestation On Sow Productivity, Piglet Robustness, And Piglet Post-Wean Growth Performance, Tiffany C. Bruhn Jan 2020

Impact Of Altering Lys : Energy Ratio During Gestation On Sow Productivity, Piglet Robustness, And Piglet Post-Wean Growth Performance, Tiffany C. Bruhn

Electronic Theses and Dissertations

Across 4 breeding groups, 63 primiparous and multiparous females were blocked by parity, balanced by weight, then randomly assigned to one of 3 gestation feeding regimens: Control (CON), 1.50 g SID Lys/Mcal ME from d2-110 of gestation; Phase Feeding 1 (PF1), 1.50 g SID Lys/Mcal ME from d2-89 and 2.11 g SID Lys/Mcal ME from d 90-110 of gestation; Phase Feeding 2 (PF2), 1.25, 1.07, and 0.88g SID Lys/Mcal ME from d2-89 for gilts, parity 1, and parity 2+, respectively and 2.11 g SID Lys/Mcal ME from d90-110 of gestation over 2 reproductive cycles. During lactation, all sows received a …


Teachers' Perceptions Of Experiential Learning In The 3-Circle Agricultural Education Model, Jon C. Schreurs Jan 2020

Teachers' Perceptions Of Experiential Learning In The 3-Circle Agricultural Education Model, Jon C. Schreurs

Electronic Theses and Dissertations

The purpose of this paper is to describe teachers’ perceptions of experiential learning and its effects on student learning, understanding, and engagement through agriculture education's three-circle model. This paper explores teachers’ perceptions of the value and importance of experiential learning in agriculture education instruction, FFA, and supervised agricultural experience. Further, I explore experiential learning, constructivism, and hands-on learning as the foundational instructional practices used in agricultural education. Agricultural education teachers from southwest Minnesota were surveyed to determine how they are using experiential learning in their agriculture education programs, including classroom instruction, FFA, and supervised agricultural experiences.


Effects Of Particle Size Of Distillers Dried Grains And Increased Levels Of Flour Enrichment - A Study Of Nutritional Composition, Rheology, And Quality Of Fiber And Protein Enriched Bread, Patra Nwamaka Akaya Jan 2020

Effects Of Particle Size Of Distillers Dried Grains And Increased Levels Of Flour Enrichment - A Study Of Nutritional Composition, Rheology, And Quality Of Fiber And Protein Enriched Bread, Patra Nwamaka Akaya

Electronic Theses and Dissertations

No abstract provided.


Predicting Farinograph Stability Of Wheat Flour With Mixograph And Glutomatic Tests, Brooke Shumate Jan 2020

Predicting Farinograph Stability Of Wheat Flour With Mixograph And Glutomatic Tests, Brooke Shumate

Electronic Theses and Dissertations

Hard red spring wheat (Triticum aestivum L.; HRSW) flour is typically used to produce wheat-based foods where dough strength is a key quality component. Maintaining acceptable levels of dough strength is an important goal in the development of new HRSW cultivars. In a commercial setting, dough strength is often measured as Farinograph stability, though due to various resource constraints, stability is often predicted in breeding programs via other methods like the Mixograph. The objective of this research was to combine Glutomatic with Mixograph data to determine whether Farinograph stability predictions might be improved over the use of Mixograph data …


Exploring The Properties Of Chitin For Promoting Tissue Engineering And Repair, M. Jahir Raihan Jan 2020

Exploring The Properties Of Chitin For Promoting Tissue Engineering And Repair, M. Jahir Raihan

Electronic Theses and Dissertations

No abstract provided.


Evaluation Of Fall-Seeded Cover Crops For Grassland Nesting Waterfowl In Eastern South Dakota, Charles W. Gallman Iii Jan 2020

Evaluation Of Fall-Seeded Cover Crops For Grassland Nesting Waterfowl In Eastern South Dakota, Charles W. Gallman Iii

Electronic Theses and Dissertations

The Prairie Pothole Region is the primary breeding ground for many species of North American waterfowl. This landscape was historically dominated by mixed and tallgrass prairies interspersed with wetlands, but >70% of native grassland area has been lost due to widespread conversion to croplands, which may threaten waterfowl production. Cover cropping is a re-emerging farming technique that may provide suitable nesting cover for grassland nesting waterfowl on active farmlands. My research objectives were to evaluate the utility of fall-seeded cover crops to breeding waterfowl compared to perennial cover, determine if cover crops in rotation with row crops can successfully support …


Physiological Responses To Feeding A Yeast Culture Supplement To Transition Dairy Cows, Nathaly Ana Carpinelli Jan 2020

Physiological Responses To Feeding A Yeast Culture Supplement To Transition Dairy Cows, Nathaly Ana Carpinelli

Electronic Theses and Dissertations

The transition period is the dynamic stage in the lactation cycle, where the most metabolic changes can occur. The use of nutritional strategies, such as yeast culture, can help cows during the transition from pregnancy to early lactation, improving health and decreasing the incidence of metabolic disorders. The first objective of this research was to evaluate the effects of a commercial yeast culture product (YC; Cellerate Culture Classic HD, Phibro Animal Health, Teaneck, NJ) on performance, blood biomarkers, and rumen fermentation and bacterial population in dairy cows during the transition period through 50 days in milk (DIM). Overall, the results …


Developing Microbial Based Process To Produce High Value Natural Antimicrobial (Glyceollin) In Soybeans And Pullulan From Sucrose, Andrea Zavadil Jan 2020

Developing Microbial Based Process To Produce High Value Natural Antimicrobial (Glyceollin) In Soybeans And Pullulan From Sucrose, Andrea Zavadil

Electronic Theses and Dissertations

Glyceollin is a secondary metabolite produced under stress conditions by soybean to act as a plant defender to pathogen attack. The antimicrobial nature of glyceollin makes it a promising natural alternative to antibiotics if incorporated into livestock feed. However, production of glyceollin is highly variable, dependent on soybean variety, and fungal elicitor used as inoculum. Our study compares two fungal spore elicitors, Trichoderma reesei and Aspergillus sojae on soybeans of diverse maturity level, and fungal susceptibility to determine highest glyceollin titer. Spore inoculation with T. reesei elicited highest glyceollin titers of 2.42±0.20 mg/g at 120 h, while A. sojae elicited …


Crop Rotations And Cover Crops Influences On Soil Biochemical Properties, Root Characteristics And Economic Performance, Hanxiao Feng Jan 2020

Crop Rotations And Cover Crops Influences On Soil Biochemical Properties, Root Characteristics And Economic Performance, Hanxiao Feng

Electronic Theses and Dissertations

Introducing cover crops (CC) and increasing crop diversity in agricultural systems are beneficial in improving the soil health and crop production. However, limited research has been conducted that focuses the influence of CC and crop rotation on soil ecosystem, root growth and development, crop production, and economic returns. The objectives of this study were to (i) assess the impacts of CC management on soil enzyme activities and soil microbial community structure changes, (ii) evaluate the crop rotation management on crop root growth and development, nutrient storage in crop grain and biomass, and crop yield, and (iii) investigate the crop rotation …


Single Droplet Drying Technology For The Optimization Of The Dairy Ingredients With Best Quality And Functionality, Hiral Narendrabhai Vora Jan 2020

Single Droplet Drying Technology For The Optimization Of The Dairy Ingredients With Best Quality And Functionality, Hiral Narendrabhai Vora

Electronic Theses and Dissertations

As a result of their extended shelf-life, dried dairy ingredients constitute a significant category produced for global markets. During the development of dairy ingredients, several drying trials are typically conducted to determine optimum drying conditions. The results of these trials can be critical in determining optimum dryer design. However, these trials can be expensive and time-consuming. An alternative that has recently been developed using a new technique called single droplet drying (SDD). The SDD technique involves a single droplet suspended on the tip of a glass filament, where changes in droplet diameter, mass, and temperature are measured during drying. SDD …


Into The River, University Of Dayton. River Stewards Jan 2020

Into The River, University Of Dayton. River Stewards

Rivers Institute Publications

This picture book, written by the 2020 cohort of River Stewards for the third-grade reading level, takes readers on a colorful adventure through the Great Miami River.

The writing process began in the fall of 2019 with events with area watershed leaders, educators and children. After children wrote and drew their favorite memories from the river, the River Stewards employed the children’s words and pictures to help articulate the landmarks, lessons and literary elements in the book.

In the spring of 2020, the River Stewards wrote, illustrated and designed the book — a story that incorporates local landmarks, fundamental watershed …


Neuroprotective Effects Of Cardiorespiratory Fitness On White Matter Integrity And Cognition Across The Adult Lifespan, Ryan A. Mace Jan 2020

Neuroprotective Effects Of Cardiorespiratory Fitness On White Matter Integrity And Cognition Across The Adult Lifespan, Ryan A. Mace

Psychology Department Dissertations

Objective: Cardiorespiratory fitness (CRF) is associated with decreased risk for cognitive decline. Accumulating evidence has linked CRF to more conserved white matter (WM) integrity and better cognitive performance in older adults. Additional research is needed to determine: (1) which WM tracts are most strongly related to CRF, (2) whether CRF-related benefits on WM translate to enhanced executive functioning (EF), and (3) if the neuroprotective effects of CRF are age-dependent. This study aimed to evaluate CRF as an intervention for modulating decreased WM integrity and EF in aging. Method: Participants were community-dwelling adults (N = 499; ages 20-85) from the open-access …


Selfish Plants And Multispecies Creativity: Alternative Narratives In Environmental Discourse, Abigail Davidovna Bowen Jan 2020

Selfish Plants And Multispecies Creativity: Alternative Narratives In Environmental Discourse, Abigail Davidovna Bowen

The Expositor: A Journal of Undergraduate Research in the Humanities

No abstract provided.


Real Food Challenge And Climate Impact Assessment: A Food System Analysis At Santa Clara University, 2018-19, Emma Mccurry, Paige Whittaker Jan 2020

Real Food Challenge And Climate Impact Assessment: A Food System Analysis At Santa Clara University, 2018-19, Emma Mccurry, Paige Whittaker

Sustainable Food Systems Fellowship

Two undergraduate students at Santa Clara University were hired to work as Food Systems Fellows from April to October, 2019. This position was co-sponsored by the Center for Sustainability and the Auxiliary Services division. The goal of this work was to explore the Santa Clara University food system’s impact on the environment from both an ecological and a social perspective and identify opportunities for improvement.

The Fellows utilized standards and core values from The Real Food Challenge, a national non-profit dedicated to leveraging the power of colleges and universities to increase equity and sustainability in food systems. The Real Food …


Evaluating Prevalence And Mortality Of External Injuries On Loggerhead (Caretta Caretta) And Green (Chelonia Mydas) Sea Turtles In Florida, Usa, Aleah Marie Ataman Jan 2020

Evaluating Prevalence And Mortality Of External Injuries On Loggerhead (Caretta Caretta) And Green (Chelonia Mydas) Sea Turtles In Florida, Usa, Aleah Marie Ataman

USF St. Petersburg campus Master's Theses (Graduate)

Anthropogenic threats, such as bycatch, boat strikes, and pollution, account for two to three times more sea turtle mortality events than natural causes. The goals of this study were to: (1) determine prevalence and cause of external traumatic injuries on nesting loggerhead sea turtles (Caretta caretta) in Juno Beach, Florida and (2) conduct an analysis of historical rehabilitation data from Florida Fish and Wildlife Conservation Commission (FWC) to calculate mortality of loggerhead and green (Chelonia mydas) turtles injured by boats. During the 2019 nesting season, 300 loggerheads were tagged and examined for external injuries. All injuries were categorized based on …


The Legal Envelope Theorem, Daniel A. Weisbach, Daniel J. Hemel Jan 2020

The Legal Envelope Theorem, Daniel A. Weisbach, Daniel J. Hemel

Coase-Sandor Institute for Law & Economics Research Paper Series

Non-tax legal rules regulating the workplace, the 6inancial sector, real property, and many other areas affect the ability of governments to collect revenues and provide public goods. Yet tax-collection considerations rarely enter into economic analyses of non-tax legal rules. Usually, tax-collection concerns are shunted aside to separate studies (and separate law-school courses) rather than being integrated into debates in non-tax spheres. This separation between non-tax legal rules and tax- collection considerations bears signi6icant negative consequences for the ability of law and economics to generate descriptively accurate and normatively attractive accounts of important non-tax legal questions.

This Article takes a step …


The Essences Of Objects: Explicating A Theory Of Essence In Object-Oriented Ontology, Stanford Howdyshell Jan 2020

The Essences Of Objects: Explicating A Theory Of Essence In Object-Oriented Ontology, Stanford Howdyshell

Philosophy Faculty Publications

In this paper, I will discuss the need for a theory of essences within Object-Oriented Ontology (OOO) and then formulate one. I will do so by drawing on Graham Harman’s work on OOO and Martin Heidegger’s thought on the essence of being, presented in his Introduction to Metaphysics. Harman touches on essences, describing them as the tension between a withdrawn object and its withdrawn qualities, but fails to distinguish between essential and inessential qualities within this framework. To fill in the gaps, I will turn to Heidegger’s explication of phusis in order to show that an essential aspect of …


The Aspet Mentoring Network: Enhancing Diversity And Inclusion Through Career Coaching Groups Within A Scientific Society, Veronica Y. Womack, Bhoomi K. Thakore, Christine V. Wood, David C. Jewett, Remi F. Jones, Susan L. Ingram, Janet A. Clark, Catherine L. Fry, Lynn Wecker, Richard Mcgee Jan 2020

The Aspet Mentoring Network: Enhancing Diversity And Inclusion Through Career Coaching Groups Within A Scientific Society, Veronica Y. Womack, Bhoomi K. Thakore, Christine V. Wood, David C. Jewett, Remi F. Jones, Susan L. Ingram, Janet A. Clark, Catherine L. Fry, Lynn Wecker, Richard Mcgee

Psychiatry & Behavioral Neurosciences Faculty Publications

Over the past decades, two persisting priorities in science, technology, engineering, and mathematics (STEM) training have been: 1) increasing the knowledge of and access to careers beyond academic scientist; and 2) increasing the diversity of the STEM workforce. Previous studies show that a uniquely constructed career coaching group provides strong support and progress for both priorities. This report extends this design into a more sustainable model that is positioned within the professional context of rising young scientists. This new model is based in the American Society for Pharmacology and Experimental Therapeutics (ASPET)—the ASPET Mentoring Network. Groups of PhD students and …


Mesenchymal Stem Cell Therapy Alleviates The Neuroinflammation Associated With Acquired Brain Injury, Brooke Bonsack, Sydney Corey, Alex Shear, Matt Heyck, Blaise Cozene, Nadia Sadanandan, Henry Zhang, Bella Gonzales-Portillo, Michael Sheyner, Cesar V. Borlongan Jan 2020

Mesenchymal Stem Cell Therapy Alleviates The Neuroinflammation Associated With Acquired Brain Injury, Brooke Bonsack, Sydney Corey, Alex Shear, Matt Heyck, Blaise Cozene, Nadia Sadanandan, Henry Zhang, Bella Gonzales-Portillo, Michael Sheyner, Cesar V. Borlongan

Neurosurgery and Brain Repair Faculty Publications

Ischemic stroke and traumatic brain injury (TBI) comprise two particularly prevalent and costly examples of acquired brain injury (ABI). Following stroke or TBI, primary cell death and secondary cell death closely model disease progression and worsen outcomes. Mounting evidence indicates that long-term neuroinflammation extensively exacerbates the secondary deterioration of brain structure and function. Due to their immunomodulatory and regenerative properties, mesenchymal stem cell transplants have emerged as a promising approach to treating this facet of stroke and TBI pathology. In this review, we summarize the classification of cell death in ABI and discuss the prominent role of inflammation. We then …


Advancing Stem Cell Therapy For Repair Of Damaged Lung Microvasculature In Amyotrophic Lateral Sclerosis, Svitlana Garbuzova-Davis, Robert Shell, Hilmi Mustafa, Surafuale Hailu, Alison E. Willing, Paul R. Sanberg, Cesar V. Borlongan Jan 2020

Advancing Stem Cell Therapy For Repair Of Damaged Lung Microvasculature In Amyotrophic Lateral Sclerosis, Svitlana Garbuzova-Davis, Robert Shell, Hilmi Mustafa, Surafuale Hailu, Alison E. Willing, Paul R. Sanberg, Cesar V. Borlongan

Neurosurgery and Brain Repair Faculty Publications

Amyotrophic lateral sclerosis (ALS) is a fatal disease of motor neuron degeneration in the brain and spinal cord. Progressive paralysis of the diaphragm and other respiratory muscles leading to respiratory dysfunction and failure is the most common cause of death in ALS patients. Respiratory impairment has also been shown in animal models of ALS. Vascular pathology is another recently recognized hallmark of ALS pathogenesis. Central nervous system (CNS) capillary damage is a shared disease element in ALS rodent models and ALS patients. Microvascular impairment outside of the CNS, such as in the lungs, may occur in ALS, triggering lung damage …


Foraminal Ligaments Tether Upper Cervical Nerve Roots: A Potential Cause Of Postoperative C5 Palsy, Andrew S. Jack, Brooks R. Osburn, Zane A. Tymchak, Wyatt L. Ramey, Rod J. Oskouian, Robert A. Hart, Jens R. Chapman, Line G. Jacques, R. Shane Tubbs Jan 2020

Foraminal Ligaments Tether Upper Cervical Nerve Roots: A Potential Cause Of Postoperative C5 Palsy, Andrew S. Jack, Brooks R. Osburn, Zane A. Tymchak, Wyatt L. Ramey, Rod J. Oskouian, Robert A. Hart, Jens R. Chapman, Line G. Jacques, R. Shane Tubbs

Neurosurgery and Brain Repair Faculty Publications

Background: Nerve root tethering upon dorsal spinal cord (SC) migration has been proposed as a potential mechanism for postoperative C5 palsy (C5P). To our knowledge, this is the first study to investigate this relationship by anatomically comparing C5–C6 nerve root translation before and after root untethering by cutting the cervical foraminal ligaments (FL).

Objective: The aim of this study is to determine if C5 root untethering through FL cutting results in increased root translation.

Methods: Six cadaveric dissections were performed. Nerve roots were exposed via C4–C6 corpectomies and supraclavicular brachial plexus exposure. Pins were inserted into the C5–C6 roots and …


Cell Therapy For Central Nervous System Disorders: Current Obstacles To Progress, Takao Yasuhara, Satoshi Kawauchi, Kyohei Kin, Jun Morimoto, Masahiro Kameda, Tatsuya Sasaki, Brooke Bonsack, Chase Kingsbury, Naoki Tajiri, Cesar V. Borlongan, Isao Date Jan 2020

Cell Therapy For Central Nervous System Disorders: Current Obstacles To Progress, Takao Yasuhara, Satoshi Kawauchi, Kyohei Kin, Jun Morimoto, Masahiro Kameda, Tatsuya Sasaki, Brooke Bonsack, Chase Kingsbury, Naoki Tajiri, Cesar V. Borlongan, Isao Date

Neurosurgery and Brain Repair Faculty Publications

Cell therapy for disorders of the central nervous system has progressed to a new level of clinical application. Various clinical studies are underway for Parkinson's disease, stroke, traumatic brain injury, and various other neurological diseases. Recent biotechnological developments in cell therapy have taken advantage of the technology of induced pluripotent stem (iPS) cells. The advent of iPS cells has provided a robust stem cell donor source for neurorestoration via transplantation. Additionally, iPS cells have served as a platform for the discovery of therapeutics drugs, allowing breakthroughs in our understanding of the pathology and treatment of neurological diseases. Despite these recent …


Translating Intracarotid Artery Transplantation Of Bone Marrow-Derived Ncs-01 Cells For Ischemic Stroke: Behavioral And Histological Readouts And Mechanistic Insights Into Stem Cell Therapy, Yuji Kaneko, Jea-Young Lee, Naoki Tajiri, Julian P. Tuazon, Trenton Lippert, Eleonora Russo, Seong-Jin Yu, Brooke Bonsack, Sydney Corey, Alexandreya B. Coats, Chase Kingsbury, Thomas N. Chase, Minako Koga, Cesar V. Borlongan Jan 2020

Translating Intracarotid Artery Transplantation Of Bone Marrow-Derived Ncs-01 Cells For Ischemic Stroke: Behavioral And Histological Readouts And Mechanistic Insights Into Stem Cell Therapy, Yuji Kaneko, Jea-Young Lee, Naoki Tajiri, Julian P. Tuazon, Trenton Lippert, Eleonora Russo, Seong-Jin Yu, Brooke Bonsack, Sydney Corey, Alexandreya B. Coats, Chase Kingsbury, Thomas N. Chase, Minako Koga, Cesar V. Borlongan

Neurosurgery and Brain Repair Faculty Publications

The present study used in vitro and in vivo stroke models to demonstrate the safety, efficacy, and mechanism of action of adult human bone marrow-derived NCS-01 cells. Coculture with NCS-01 cells protected primary rat cortical cells or human neural progenitor cells from oxygen glucose deprivation. Adult rats that were subjected to middle cerebral artery occlusion, transiently or permanently, and subsequently received intracarotid artery or intravenous transplants of NCS-01 cells displayed dose-dependent improvements in motor and neurological behaviors, and reductions in infarct area and peri-infarct cell loss, much better than intravenous administration. The optimal dose was 7.5 × 106 cells/mL when …


Resolvin E1 Derived From Eicosapentaenoic Acid Prevents Hyperinsulinemia And Hyperglycemia In A Host Genetic Manner, Anandita Pal, Abrar E. Al-Shaer, William Guesdon, Maria J. Torres, Michael Armstrong, Kevin Quinn, Traci Davis, Nichole Reisdorph, P. Darrell Neufer, Espen E. Spangenburg, Ian Carroll, Richard P. Bazinet, Ganesh V. Halade, Joan Clària, Saame Raza Shaikh Jan 2020

Resolvin E1 Derived From Eicosapentaenoic Acid Prevents Hyperinsulinemia And Hyperglycemia In A Host Genetic Manner, Anandita Pal, Abrar E. Al-Shaer, William Guesdon, Maria J. Torres, Michael Armstrong, Kevin Quinn, Traci Davis, Nichole Reisdorph, P. Darrell Neufer, Espen E. Spangenburg, Ian Carroll, Richard P. Bazinet, Ganesh V. Halade, Joan Clària, Saame Raza Shaikh

Internal Medicine Faculty Publications

The FASEB Journal published by Wiley Periodicals LLC on behalf of Federation of American Societies for Experimental Biology Eicosapentaenoic acid (EPA) has garnered attention after the success of the REDUCE-IT trial, which contradicted previous conclusions on EPA for cardiovascular disease risk. Here we first investigated EPA's preventative role on hyperglycemia and hyperinsulinemia. EPA ethyl esters prevented obesity-induced glucose intolerance, hyperinsulinemia, and hyperglycemia in C57BL/6J mice. Supporting NHANES analyses showed that fasting glucose levels of obese adults were inversely related to EPA intake. We next investigated how EPA improved murine hyperinsulinemia and hyperglycemia. EPA overturned the obesity-driven decrement in the concentration …


Decimated Little Brown Bats Show Potential For Adaptive Change, Giorgia G. Auteri, L. L. Knowles Jan 2020

Decimated Little Brown Bats Show Potential For Adaptive Change, Giorgia G. Auteri, L. L. Knowles

KIP Articles

The degree to which species can rapidly adapt is key to survival in the face of climatic and other anthropogenic changes. For little brown bats (Myotis lucifugus), whose populations have experienced declines of over 90% because of the introduced fungal pathogen that causes white-nose syndrome (WNS), survival of the species may ultimately depend upon its capacity for adaptive change. Here, we present evidence of selectively driven change (adaptation), despite dramatic nonadaptive genomic shifts (genetic drift) associated with population declines. We compared the genetic makeups of wild survivors versus non-survivors of WNS, and found significant shifts in allele frequencies of genes …


Welcome To The World Of Tomorrow: An Exploration Of Cell-Based Meats And How The Fda And Usda May Protect Intellectual Property Rights, Sean A. Grafton Jan 2020

Welcome To The World Of Tomorrow: An Exploration Of Cell-Based Meats And How The Fda And Usda May Protect Intellectual Property Rights, Sean A. Grafton

Catholic University Journal of Law and Technology

Lab-grown meats are ready to be sold in United States markets. However, the meat product needs approval from regulators such as the Food and Drug Administration (“FDA”) and the United States Department of Agriculture (“USDA”). The regulation approval process takes a significant amount of time. This approval period will cut into the lab-grown meat producers’ patent time, rendering a period of the patent ineffective.

This Comment analyzes the effect of, and possible changes to, our current laws on the emerging lab-grown meat market. To look at this problem, this Comment compares FDA and USDA regulations, analyzes the Hatch-Waxman Act, and …


The "Threat" Of Marriage Fraud: A Story Of Precarity, Exclusion, And Belonging, Sarah Pringle Jan 2020

The "Threat" Of Marriage Fraud: A Story Of Precarity, Exclusion, And Belonging, Sarah Pringle

Canadian Journal of Family Law

Migrants can obtain permanent residency in Canada under the family-reunification category set out in s. 12(1) of the Immigration and Refugee Protection Act (IRPA). Canadian citizens or permanent residents may apply to sponsor their non-citizen spouse, common law or conjugal partner, or other relatives to move to Canada pursuant to s. 117(1)(a) of the Immigration and Refugee Protection Regulations (IRPR). The bad-faith clause under s. 4(1) of the IRPR requires spousal-sponsorship applicants to prove to visa officers that, on a balance of probabilities, their relationship is “genuine” and not “entered into primarily for the purpose of …


Rod-Shape Theranostic Nanoparticles Facilitate Antiretroviral Drug Biodistribution And Activity In Human Immunodeficiency Virus Susceptible Cells And Tissues, Bhavesh D. Kevadiya, Brendan Ottemann, Insiya Z. Mukadam, Laura Castellanos, Kristen Sikora, James R. Hilaire, Jatin Machhi, Jonathan Herskovitz, Dhruvkumar Soni, Mahmudul Hasan, Wenting Zhang, Anandakumar Sarella, Jered Garrison, Joellyn Mcmillan, Benson Edagwa, R. Lee Mosley, Richard W. Vachet, Howard E. Gendelman Jan 2020

Rod-Shape Theranostic Nanoparticles Facilitate Antiretroviral Drug Biodistribution And Activity In Human Immunodeficiency Virus Susceptible Cells And Tissues, Bhavesh D. Kevadiya, Brendan Ottemann, Insiya Z. Mukadam, Laura Castellanos, Kristen Sikora, James R. Hilaire, Jatin Machhi, Jonathan Herskovitz, Dhruvkumar Soni, Mahmudul Hasan, Wenting Zhang, Anandakumar Sarella, Jered Garrison, Joellyn Mcmillan, Benson Edagwa, R. Lee Mosley, Richard W. Vachet, Howard E. Gendelman

Nebraska Center for Materials and Nanoscience: Faculty Publications

Human immunodeficiency virus theranostics facilitates the development of long acting (LA) antiretroviral drugs (ARVs) by defining drug-particle cell depots. Optimal drug formulations are made possible based on precise particle composition, structure, shape and size. Through the creation of rod-shaped particles of defined sizes reflective of native LA drugs, theranostic probes can be deployed to measure particle-cell and tissue biodistribution, antiretroviral activities and drug retention.

Methods: Herein, we created multimodal rilpivirine (RPV) 177lutetium labeled bismuth sulfide nanorods (177LuBSNRs) then evaluated their structure, morphology, configuration, chemical composition, biological responses and adverse reactions. Particle biodistribution was analyzed by single …