When A Little Goes A Long Way: Expanding Home Care Services To Adults With Disabilities, Serena Hasworth, Jaclyn Winfree, Ozcan Tunalilar, Diana L. White

Institute on Aging Publications

Policy makers are increasingly interested in reducing public spending while maintaining quality of life. Since 1975, Oregon Project Independence (OPI) has supported community-based adults aged 60 and older to avoid or delay the need for residential long-term care services by increasing access to personal and home care services. The program also aims to prevent the need for Medicaid by optimizing personal resources and natural supports. In 2014, the OPI Expansion (OPI-E) pilot project began to serve adults aged 18-59 with disabilities in seven of Oregon’s seventeen Area Agencies on Aging (AAAs). This poster describes the evaluation of the expansion using …

Indirect Relatedness, Evaluation, And Visualization For Literature Based Discovery, Sam Henry

Theses and Dissertations

The exponential growth of scientific literature is creating an increased need for systems to process and assimilate knowledge contained within text. Literature Based Discovery (LBD) is a well established field that seeks to synthesize new knowledge from existing literature, but it has remained primarily in the theoretical realm rather than in real-world application. This lack of real-world adoption is due in part to the difficulty of LBD, but also due to several solvable problems present in LBD today. Of these problems, the ones in most critical need of improvement are: (1) the over-generation of knowledge by LBD systems, (2) a …

The Nail That Sticks Up Isn't Always Hammered Down: Women, Employment Discrimination, And Litigiousness In Japan, Kristen Luck

Theses and Dissertations

Much recent scholarship is devoted to projecting Japan’s future and analyzing its prospects as a global power. After two decades of economic stagnation, alarming demographic trends, and the 3/11 triple disaster, some scholars argue that Japan is grappling with an era of precarity, marked with instability and anxiety. Prime Minister Shinzo Abe returned to office in 2012, promoting his economic reform policy, “Abenomics” and within the third “arrow" of this approach targeting structural reforms, he promoted “womenomics”, a term coined by Kathy Matsui of Goldman-Sachs. Prime Minister Abe’s objective is to create a society where "women can shine” and women …

Effects Of Reference Image Selection On The Alignment Of Free-Breathing Lung Cancer Patients During Setup Imaging: Average Intensity Projection Versus Mid-Ventilation, Samantha Conrad

Theses and Dissertations

Abstract

Purpose: The purpose of this paper is to quantify if using an average intensity projection (AIP) scan or a 30% phase (mid-ventilation surrogate, MidV) scan as the reference image for patient position verification affects reproducibility of lung cancer patient alignment under free-breathing cone beam computed tomography (CBCT) image guidance and to analyze the effects of common clinical issues on registration variability.

Methods: AIPs were retrospectively created for 16 lung patients (14 SBRT, 2 conventional treatments) originally planned/treated using the 30% phase MidV surrogate scan as reference. The study included 3-5 CBCTs from each patient. Registrations were performed …

Aeg-1 Knockout Sensitizes Hepatocellular Carcinoma (Hcc) Cells To Ionizing Radiation, Maheen Khan

Theses and Dissertations

Liver cancer is the fourth leading cause of cancer-associated deaths globally, and among primary liver cancers, hepatocellular carcinoma (HCC) encompasses 75-85% of all cases. HCC is a highly lethal disease due to limited treatment options – only a small subset of patients qualify for surgical resection or transplantation; the remaining patients often display resistance to radiation therapy or chemotherapy. Overexpression of the oncogene astrocyte elevated gene-1 (AEG-1) is associated with poorer survival and increased tumor recurrence in HCC, and numerous studies show its role in initiation of hepatocarcinogenesis. A prior study also demonstrated AEG-1 expression inhibits senescence by diminishing the …

Regenerative Potential Of Mesenchymal Stem Cell Derived Exosomes, Andrew P. Wong

Theses and Dissertations

Bone defects are a pervasive complication arising from many clinical conditions, both mechanical and pathological. Current treatments for large bony defects focus on applying bone grafts or synthetic materials to the defect area. Cell-based—and especially stem-cell—therapies have advanced greatly thanks to increasing attention focused on their ability to generate new tissues in situ with biomechanical properties approaching that of native tissue, but they suffer from their own shortcomings as well. Exosomes have been shown to play critical roles in cell-signaling and tissue regeneration and are therefore potentially ideal therapeutic vehicles for treating bone defects. Exosomes are small microvesicles counted amongst …

Bantaba: Designing The Sacred Circle, Tashiara Scott

Theses and Dissertations

MOTIVATION In Richmond, there are 1.21 times as many African Americans as any other ethnic group. Yet 63.4% of African Americans live in poverty (Richmond, VA). African Americans face greater exposure to stress due to low socioeconomic status and poverty. In these communities, “discrimination and deprivation undermine individuals’ ability to accumulate the social and material resources to mitigate the effects of stress” (Brondolo, 2018). In this city’s African American community, where stress levels are high and consequential health concerns are prevalent, dance can be a remedy for managing stress and improving health (Hanna, 2006).

DESIGN PROBLEM How can an intentionally …

I Thought The Earth Remembered Me, Hannah Bates

Theses and Dissertations

The forest is teeming with activity: fungi transform dead logs into nutrients, roots entangle themselves with the earth, and strong winds break resilient boughs. Like the forest, the human body functions according to a complex system of agents - from the micro bacteria in the gut to the pores of the skin. The built world has often been rendered in opposition to these processes of nature. As a vessel through which the world is experienced, the body is an intermediary between raw matter and fabricated things. The planet is suffused with human life, and there is a critical tension between …

Fluvastatin And Microrna-146a Alter Interleukin-33 Mediated Mast Cell Functions., Marcela Taruselli

Theses and Dissertations

Mast cells are tissue-resident immune cells known as effector cells for the innate and adaptive immune systems. Mast cells contribute to host defenses against parasites such as large roundworm parasites, bacterial pathogens, and toxins, and participate in wound healing, but they are mostly known for their role in allergic diseases. It has been well established that during allergic diseases, mast cells are stimulated by IgE cross-linkage to release proinflammatory mediators. However, a newly discovered cytokine, IL-33 has also been implicated in allergic disease. Recently, IL-33 has been implicated as a driver of several Type I sensitivities and previous studies have …

The Mountains At The End Of The World: Subcultural Appropriations Of Appalachia And The Hillbilly Image, 1990-2010, Paul L. Robertson

Theses and Dissertations

There is an aversion within the field of Appalachian Studies to addressing the cultural formulations of the Appalachian/hillbilly/mountaineer as an icon of aggressive resistance. The aversion is understandable, as for far too long images of the irrationally and savagely violent mountaineer were integral to the most gross popular culture stereotypes of Appalachia. Media consumers often take pleasure or comfort in these images, which usually occur in a reactionary context with the hillbilly as either a type of nationally necessary savage OR as an unregenerate barbarian against whom a national civilization will triumph and benefit by the struggle.

I bookend my …

Light In Community: A Study In The Adaptive Reuse Of Sacred Space, Abigail Barras

Theses and Dissertations

ABSTRACT

MOTIVATION
American life is increasingly fragmented, leading to a sense of restlessness and disconnection. Much of that fragmentation can be traced to our pattern of architectural and sociological development, namely, the rise of the automobile suburbs in the 1950s and 60s and the abandonment of densely populated, human- scaled environments like that of the small town or city center (Oldenberg, 1999).

PROBLEM
Large numbers of architecturally significant buildings have fallen into disrepair over the years following the “white flight” of the 1960s and 70s, during which significant segments of investment dollars left city centers and followed to the suburbs …

Upper Thermal Limits Vary Among And Within Native Bee Species In Relation To Season, Voltinism, And Nest Type, Kálmán K. Csigi Xiv

Theses and Dissertations

Native bees are only recently gaining attention for the extent to which they aid in pollination and ecosystem services. These services are threatened by predictions of warming temperatures if bees are not able to respond. Voltinism - the number of generations produced annually- can strongly influence thermal conditions experienced by both developing and adult bees based on emergence strategies for each voltinism type. Differences in experienced thermal conditions brought on by climate change could therefore affect upper thermal limits (UTL) in bees. This study observes UTLs across a foraging season within and among native bee species vi to elucidate the …

In A Building, A Stairwell, A Room Speaks, Tsz Wai Wallis Cheung

Theses and Dissertations

Working toward a personal definition of womanhood while progressing with my research in feminist discourse, I frame biographical events alongside the intricate use of language surrounding feminist theory. Experimenting with material specificities that speak to my personal narratives and cultural significance, my work seeks to address the interlacing operations of subjectivity expanding on the intersection of class, gender and race.

The What If Collection, Aisha J. Daniels

Theses and Dissertations

The What If Collection is a visual narrative that confronts white supremacy, the social, economic, and political ideology used to subjugate black civilization via colonial rule and enslavement in history and via structural racism today. Many white people have been socialized into a racial illiteracy that fosters white supremacy. This racial illiteracy fails to realize and understand the destructive effects of Western dominance on the rest of the world, particularly on past and present Africa and her diaspora. In response, utilizing discursive design, the collection constructs a counter-story that depicts a shift in the power structure in which the white …

Weaponization Of Space: Subverting The Architecture Of Occupation, Majdulin Nasrallah

Theses and Dissertations

Israel’s illegal occupation of Palestine and oppression of the Palestinian people has manifested itself in countless ways. The built environment, fueled by spatial theory, has been transformed into an instrument of war that serves a military agenda. In this context, the physical environment is not simply the arena of conflict, but a weapon wielded by occupying forces. This research investigates spatial control through seemingly mundane architecture and military practices, which are deployed deliberately to strangulate Palestinian livelihood and prosperity. Derived from Deleuze and Guittari’s delineation of smooth and striated space, with an emphasis on walls and barriers, this thesis subverts …

Examining Relationships Among Body Image, Sexuality, And Sexual Functioning In Women With Cervical And Endometrial Cancer, Christina Wilson

Theses and Dissertations

Introduction: Over 74,000 US women are diagnosed annually with endometrial or cervical cancers and experience significant treatment-related difficulties with body image, sexuality, and sexuality. The aims of the research were to examine relationships among body image, sexuality, and sexual functioning, and understand women’s views of these concepts. A novel theoretical framework encompassing these three concepts and contextual variables guided the research.

Methods: A non-experimental cross-sectional pilot study was conducted with pre-menopausal women in an academic medical center who had stages I-III cervical or endometrial cancer, were 3-36 months post-treatment, and had no mental health diagnoses. Participants completed the …

"Quiddity | Leaving Home", Jonathan U. Barton

Theses and Dissertations

The poetry collection in four sections features pieces concerned with memory, particularly of the author’s childhood in Ireland. Difficult family relationships as well as early romantic failures are prominent obsessions. Landscapes and careful portraits of characters recur. Travel to Eastern Europe and within the author’s adopted United States give the opportunity to meditate on larger issues and spans of time. Domestic pleasures and the struggle to be a good parent and husband provide the ultimate trajectory of the work.

The nonfiction memoir consists of eight essays which tackle among other topics a failed first marriage, a return visit to the …

The Wheel House - An Intergenerational Space Creating Bonds Between At-Risk Teens And Seniors, Jessica M. Keegan

Theses and Dissertations

MOTIVATION

Two main groups in American society today are floundering: adolescent children of low income families and the elderly.

Between the hours of 3:00 and 6:00 p.m., one in five children are unsupervised. Left to their own devices, many become involved in negative behaviors such as drug and alcohol abuse, sexual activity or in the worse cases, delinquency (Afterschool Alliance, 2016). It is proven that when children are alone after school, they not only miss out on valuable learning opportunities, but also their parents are affected as well by having to lose as many as eight work days annually to …

This Must Be The Place, Eve White

Theses and Dissertations

This publication is the companion piece to “This Must Be the Place,” a 3D realization of my conceptual photography work exhibited in the Anderson Courtyard at VCU's 2019 School of the Arts MFA Show. I photograph scenes from nature and reproduce these images onto flattened plexiglass planes, arranging them in new, natural environments and photographing them again. The outcome is a scenic collage in which two unfamiliar locations become superimposed. It is my hope that as people experience the work they become a part of the texture of it.

Erasure: An Additive And Subtractive Act, Margaret Davids

Theses and Dissertations

MOTIVATION In the simplest form, a pencil mark on a page is removed by a traditional rubber eraser. However, the marks are often never fully removed, and the paper thins with each attempt to rub out an old idea.

But how does one erase a chair? A pilaster? A room? A building?... More importantly, how does the subtractive act of erasing become an additive one?

The historical fabric of a building is important; it is also imperative that it does not remain stagnant. Erasing is an opportunity to design an interior environment that both acknowledges the traces of the pencil …

Pharmacodynamics Of Monoamine Transporter Releasing Agents And Reuptake Inhibitors, Alexa Holloway

Theses and Dissertations

Ligands of the human monoamine transporters encompass a wide range of both illicit and therapeutic drugs that act upon neural circuitry related to reward, motivation, and the processing of salient stimuli. The present study utilizes two methods for analyzing transporter substrates and inhibitors in order to characterize activity and assess potency. The first measures transient changes in intracellular calcium as a surrogate for transporter activity by harnessing the electrical coupling of monoamine transporters and L-type calcium channels. This is used to analyze novel chimera of the strong hDAT inhibitors methylphenidate and ��-PPP in order to assess the contribution of specific …

Changing Her Habit: Women Writers And Needlework In Early Eighteenth-Century England, Jane B. Harwell

Theses and Dissertations

This thesis attends to the appearance of needlework within early eighteenth-century British women's writing. The central goal of this work is to complicate the seemingly oppositional relationship between the needle and the quill, as applied to women surrendering needlework for written work. Popular representations of needlework within early novels demonstrate an elision between text and textile. Further, both female-authored work and the lack of surviving embroideries elucidate the ephemerality of what is broadly defined as "Women's Work." I focus on texts between 1700-1750, however the material examples of embroidery were created as early as 1570. This timeline helps illuminate the …

Out Of The Margins: Evolving Narrative Representation Of Women In Video Games, Rowan Lucas

Theses and Dissertations

This thesis examines narrative representation of female characters in video games and how game narratives and representations contribute to socio-cultural discourse. First, this thesis explores and defines the cultural background for female representation in video games. It then defines video games as a type of text and describes the features that are unique to games, such as the use of avatars, and what impacts these features have on game narratives. The thesis attempts to establish evidence of an evolutionary arc of comprehensive female representation in video games by first exploring historical female narrative tropes, and then comparing them to narrative …

An Introduction To Supersymmetric Quantum Mechanics, Vincent R. Siggia

Theses and Dissertations

In this thesis, the general framework of supersymmetric quantum mechanics and the path integral approach will be presented (as well as the worked out example of the supersymmetric harmonic oscillator). Then the theory will be specialized to the case of supersymmetric quantum mechanics on Riemannian manifolds, which will start from a supersymmetric Lagrangian for the general case and the special case for S2. Afterwards, there will be a discussion on the superfield formalism. Concluding this thesis will be the Hamiltonian formalism followed by the inclusion of deforma- tions by potentials.

Searching For Clean Observables In $B -> D* /Tau- \Bar{\Nu}_{\Tau}$ Decays, Michael D. Williams Jr.

Theses and Dissertations

In this thesis, the clean angular observables in the $\bar{B} \to D^{*+} \ell^- \bar{\nu}_{\ell}$ angular distribution is studied. Similar angular observables are widely studied in $B \to K^* \mu^+ \mu^-$ decays. We believed that these angular observables may have different sensitivities to different new physics structures.

Nanostructured Materials For Photocatalysis, Water Treatment And Solar Desalination, Hiran D. Kiriarachchi

Theses and Dissertations

Maintaining a constant supply of clean drinking water is among the most pressing global challenges in our time. About one-third of the population is affected by the water scarcity and it can only get worse with climate change, rapid industrialization, and the population growth. Even though nearly 70 percent of the planet is covered by water, the consumable freshwater content is only 2.5 percent of it. Unfortunately, the accessible portion of it is only 1 percent. Even so, most of the freshwater bodies are choked with pollution. Considering the vast availability of saline water on the planet and the increasing …

Architect Of The New South: The Life And Legacy Of William Mahone, Heath M. Anderson

Theses and Dissertations

In Virginia following the Civil War, white and black people formed complex and shifting alliances based on their own self-interests that cut across the lines of established political parties. In this turbulent atmosphere, William Mahone forged a new biracial political coalition called the Readjuster Party in order to transform Virginia’s economy so that it would be competitive in the years to come. Chapter One argues that Mahone’s experience as a soldier and railroad man gave him the political clout needed to enter politics and an industrial vision for Virginia’s future that was markedly different from many of his contemporaries. Chapter …

Generic Of, Nicole Levaque

Theses and Dissertations

generic of is a creative text paralleling the creation of my thesis exhibition. I use fragmented layers of narrative, description and prose in the same way each handbuilt ceramic is fired multiple times, allowing the glazes to build upon themselves. This is a close study of the still life, the intimacy of consuming, and how trauma is passed through the gut.

Electronic And Geometric Structure Of Alnom And Alnom +, Albert R. Armstrong

Theses and Dissertations

Generally, the electronic stability of aluminum clusters is associated with either closed electronic shells of delocalized electrons, or aluminum in the +3 state. To explore alternative routes for electronic stability in aluminum oxide clusters, theoretical methods were used to examine the geometric and electronic structure of Al_nO_m (2≤n≤7; 1≤m≤10) clusters. Two types of electronically stable clusters with large HOMO-LUMO gaps were identified the first being Al_2nO_3m clusters with a +3 oxidation state on the aluminum, and the second being planar clusters such as Al₄O₄, Al₅O₃, Al …

Humans Aren't Boxes, Art Isn't Finite, Brianne Alta Humphreys

Theses and Dissertations

I am bored. All around me are systems that perpetuate repetitive, reductive, and mundane modes of living. In an attempt to counter a culture obsessed with singular ways of existence and bite-sized perfection, I utilize moving mediums of video and performance to dive head first into a vast array of sloppy sincerity. The crisp, white-washed, analytical, and restrictive is loudly replaced with the empirical, haphazard, and instinctual. My intention is to create and encourage raw, performative-based work that is as multifaceted as unbridled life itself. This alive and physical practice hosts a conglomeration of sweat, memories, heartbreaks, hymn singing, line …