Digital Commons Network^™

Our Place And Power: Testimonios From Latina Senior Student Affairs Officers, Julie A. Leos

USF Tampa Graduate Theses and Dissertations

Latina leadership in higher education is more important ever. This study provides an empowering understanding of the experiences of Latina Senior Student Affairs Officers (SSAOs) in higher education in the U.S. and their practices related to wielding the power and influence associated with their roles. Latino Critical Race Theory (LatCrit) (Solorzano & Yosso, 2000), Intersectionality (Crenshaw, 1988), and Borderlands Theory (Anzaldua, 1987) served as a theoretical framework for this study and provides a basis for understanding the Latina experience from a critical perspective.

A testimonio research design was used to explore the following wonderments: (1) What meaning do Latina SSAOs …

2019 November 15 - Board Of Trustees Academic, Research, And Student Success Committee Agenda And Minutes, Board Of Trustees, East Tennessee State University

Board of Trustees Agendas and Minutes

No abstract provided.

2019 November 15 - Board Of Trustees Agenda And Minutes, Board Of Trustees, East Tennessee State University

Board of Trustees Agendas and Minutes

No abstract provided.

Declining Chirping Of Hawaiian Crickets Topic For Science Cafe, Edwin B. Smith

University of Mississippi News

Susan Balenger to discuss insects' loss of ability for mating chirp at final meeting of fall

Identifying Faculty And Peer Interaction Patterns Of First-Year Biology Doctoral Students: A Latent Class Analysis, Soojeong Jeong, Jennifer M. Blaney, David F. Feldon

Instructional Technology and Learning Sciences Faculty Publications

Faculty and peer interactions play a key role in shaping graduate student socialization. Yet, within the literature on graduate student socialization, researchers have primarily focused on understanding the nature and impact of faculty alone, and much less is known about how peer interactions also contribute to graduate student outcomes. Using a national sample of first-year biology doctoral students, this study reveals distinct categories that classify patterns of faculty and peer interaction. Further, we document inequities such that certain groups (e.g., underrepresented minority students) report constrained types of interactions with faculty and peers. Finally, we connect faculty and peer interaction patterns …

Machine Learning To Quantitate Neutrophil Netosis, Laila Elsherif, Noah Sciaky, Carrington A. Metts, Md. Modasshir, Ioannis Rekleitis, Christine A. Burris, Joshua A. Walker, Nadeem Ramadan, Tina M. Leisner, Stephen P. Holly, Martis W. Cowles, Kenneth I. Ataga, Joshua N. Cooper, Leslie V. Parise

Faculty Publications

We introduce machine learning (ML) to perform classifcation and quantitation of images of nuclei from human blood neutrophils. Here we assessed the use of convolutional neural networks (CNNs) using free, open source software to accurately quantitate neutrophil NETosis, a recently discovered process involved in multiple human diseases. CNNs achieved >94% in performance accuracy in diferentiating NETotic from non-NETotic cells and vastly facilitated dose-response analysis and screening of the NETotic response in neutrophils from patients. Using only features learned from nuclear morphology, CNNs can distinguish between NETosis and necrosis and between distinct NETosis signaling pathways, making them a precise tool for …

Synthesis, Optical, And Thermal Properties Of 2,4,6-Tris(4-Substituted Phenyl)Pyrylium Tosylates And Triflimides, Pradip Kumar Bhowmik, Christina Inbok Lee, Jung Jae Koh, Haesook Han, Ahamed Jubair, Vladimir Kartazaev, Swapan Kumar Gayen

Chemistry and Biochemistry Faculty Research

A group of five 2,4,6-tris(4-substituted phenyl)pyrylium tosylates were synthesized in one-pot reaction from para-substituted benzaldehyde and para-substituted acetophenones using tosic acid as a condensing agent. The tosylate salts were converted to the corresponding triflimide salts by metathesis reactions. Chemical structures, as well as optical spectroscopic and thermal properties of these salts were studied using pertinent experimental techniques. Trimethyl- and trihalo-substituted pyrylium salts emitted strong blue light with peaks in the 456 nm–479 nm range and trimethoxy-pyrylium salts emitted intense green light with maxima around 526 nm in acetonitrile solution. Quantum yields of the solutions were rather low, but the salts …

Assessment Of Particulate Matter Toxicity And Physicochemistry At The Claim 28 Uranium Mine Site In Blue Gap, Az, Jessica G.S. Begay

Biomedical Sciences ETDs

Particulate matter (PM) inhalation is known to have adverse effects on the respiratory and cardiovascular systems. Community concerns in the southwestern US have been expressed in regions of extensive open-pit hard-rock (especially uranium) mining that windblown dusts may pose an excess health risk. To address these concerns, we have undertaken a campaign to detail: (1) the amount and composition of the PM_2.5 in the region, (2) meteorological characteristics, such as wind speed and direction, and (3) and immunological and physiological responses of mice after PM_2.5 exposures.

For toxicity studies, C57BL/6 and apolipoprotein E-null (ApoE^-/-, a vascular …

The Association Of Psychological Distress And Mental Health With English Language Acquisition Of Recently Resettled Refugees In The United States, Charlisa C. Christian

Sociology ETDs

Host country language proficiency among resettled refugees has been associated with better mental health; yet, in qualitative studies, refugees describe psychological distress acting as a barrier to their learning. To clarify varying results, this longitudinal study of refugees from Africa, the Middle East, and Afghanistan (n=290) examined language acquisition with positive mental health and psychological distress as distinct concepts on correlated unipolar dimensions (Keyes 2002; Rumbaut 1989). With multilevel modeling, initial English speaking ability was significantly related to increasing positive mental health over time, indicating host country language proficiency acts as a protective factor for refugees, and supporting the growing …

History Of The U.S. Goat Industry, Terry A. Gipson

Professional Agricultural Workers Journal

Abstract

Goats were first domesticated in the Fertile Crescent and then spread throughout the world. Goats were brought to North America into the southwestern U.S. in the 17^th century by early Spanish explorers and clergy. These goats are the ancestors of the Spanish goat of Texas and the Lamancha breed of California. English and other European settlers also brought their goats as they moved into the eastern U.S in the 18^th century. Angora goats were first imported in the U.S. in the mid-19^th century and the earliest importation of officially recognized dairy goat breeds occurred in the …

New Insights Into Anhydrobiosis Using Cellular Dielectrophoresis-Based Characterization, Mohamed Z. Rashed, Clinton J. Belott, Brett R. Janis, Michael Menze, Stuart J. Williams

Faculty and Staff Scholarship

Late embryogenesis abundant (LEA) proteins are found in desiccation-tolerant species from all domains of life. Despite several decades of investigation, the molecular mechanisms by which LEA proteins confer desiccation tolerance are still unclear. In this study, dielectrophoresis (DEP) was used to determine the electrical properties of Drosophila melanogaster (Kc167) cells ectopically expressing LEA proteins from the anhydrobiotic brine shrimp, Artemia franciscana. Dielectrophoresis-based characterization data demonstrate that the expression of two different LEA proteins, AfrLEA3m and AfrLEA6, increases cytoplasmic conductivity of Kc167 cells to a similar extent above control values. The impact on cytoplasmic conductivity was surprising, given …

Calling All Corpses: An Examination Of The Treatment Of The Dead In Old English Literature, Jessica Troy

English Language and Literature ETDs

The care and disposal of the dead bodies, an unavoidable reminder of one’s mortality, rarely receives in-depth literary attention. In early medieval England, the Anglo-Saxons dealt with corpses but seldom discussed the undertaking in written documents. Instead they focused on the grandiose deeds of heroes like Beowulf and the holy lives of revered saints.

This dissertation examines various genres of Old English literature to identify times when authors discuss corpses and to what end these discussions led. Hagiographers, for example, describe the corpses of certain saints such as Æthelthryth and Edmund at length while the bodies of other saints are …

High Ammonia Strength Wastewater Treatment Using Algae, Bacteria And Ion Exchange, Nadezhda Zalivina

USF Tampa Graduate Theses and Dissertations

Nitrogen pollution has been considered one of the major problems of the 21st century. Discharge of nitrogen from improperly treated wastewaters into surface water bodies causes eutrophication and hypoxia, which results in significant environmental, public health and economic damages. In addition to the incoming flow, wastewater treatment plants generate internal highly concentrated ammonium streams, such as anaerobic digestion sidestream. As a current practice, sidestream without prior treatment is returned to the head of the plant, which increases the total incoming nitrogen load by 20-30% and often exceeds the treatment capacity. The most commonly used conventional biological nitrogen removal processes are …

Effect Of Atypical Protein Kinase C Inhibitor (Dnda) On Cell Proliferation And Migration Of Lung Cancer Cells, Raja Reddy Bommareddy

USF Tampa Graduate Theses and Dissertations

Lung cancer is the second most common cancer, and it is the leading cause of cancer death in both men and women. Elevated levels of PKC-ι and FAK are implicated in the progression of lung cancer and involved in cell proliferation, apoptosis, cell survival, and cell migration processes. Lung cancer diagnosis typically occurs in the late stages, which limits the treatment options. Hence, there is a dire need to develop drugs that are effective and safe to treat lung cancers. We used a novel aPKC inhibitor named DNDA (3,4-amino-2,7 napthalene disulfonic acid) to study the role of atypical PKCs (aPKCs) …

Rescue Of Hearing And Protection Of Auditory Structures From Noise-Induced Hearing Loss, Reza Amanipour

USF Tampa Graduate Theses and Dissertations

Hearing loss due to exposure to high level sound is a major health problem that causes permanent hearing impairment and has a significant impact on job productivity and quality of life. A large population suffers from noise-induced hearing loss (NIHL), a disorder for which there is currently no FDA-approved prevention, treatment or cure. The goal of my dissertation work is to provide insights into the effects of noise trauma on hearing abilities of normal hearing subjects, and determine how a new therapeutic compound (mGlu7 modulator) can protect and/or prevent loss of, or damage to sensory cells and brain neurons, including …

Trial & Error: Royal Authority & Families In The Colonization Of The British Floridas, 1763-1784, Deborah L. Bauer

USF Tampa Graduate Theses and Dissertations

This dissertation will examine the relationship between families, the British Crown, and colonization patterns in mid-eighteenth-century Florida. Agents of royal authority, such as colonial governors, and White, European, Protestant families, would serve as the bulwark upon which the Crown would design and implement its ideal colonization scheme. Carefully created by royal officials, adherence to the plan would result in the successful establishment and growth of loyal and productive colonies. Noncompliance ultimately foreshadowed failure. The state used the social unit of families in East and West Florida as a "tool of empire” to ensure the political, economic, and military success of …

Ecological Responses Of Seascape Heterogeneity, Dinorah H. Chacin

USF Tampa Graduate Theses and Dissertations

A core aim of landscape ecologists as well as conservation and management practices has been to understand how processes that structure communities vary as a function of landscape context. Landscape heterogeneity (i.e. landscape composition, configuration) and fine-scale habitat characteristics can influence ecological interactions across habitat patches at a range of scales. Therefore, the main objective of this work is to apply a landscape ecology perspective to understand how seascape heterogeneity can influence demographic rates, community patterns, and ecological processes. To accomplish this overall goal, I conducted a literature review on oyster reefs from a seascape ecology perspective (Chapter 1) and …

The Activity And Structure Of Cu2+-Biomolecules In Disease And Disease Treatment, Darrell Cole Cerrato

USF Tampa Graduate Theses and Dissertations

Despite its relatively low concentration in the human body, copper is an essential transition metal ion. Under normal circumstances, it is a well-regulated trace element that is introduced via diet or environment depending on the organism. Its strong reactivity and binding to some biologically essential chemicals can be detrimental to the host organism. Herein the oxidative chemistry of copper and its possible prevention in humans and agricultural organisms is discussed, as well as the potential avenues as metal-targeting disease treatment via novel-peptide and peptoid products.

In the first study, copper is implicated in the progression and onset of Alzheimer’s disease. …

Lung Cancer Cells Survive Egfr Tki Exposure Through Upregulation Of Cholesterol Synthesis, Mark Howell

USF Tampa Graduate Theses and Dissertations

Lung cancer is the number one cause of cancer related death in both males and females. About 20% of all non-small cell lung cancer (NSCLC) patients are expected to harbor an epidermal growth factor receptor (EGFR) activating mutation. EGFR inhibitors have been shown to provide clinical benefits over chemotherapy for lung cancer patients with EGFR activating mutations. However, despite the initial clinical responses to these EGFR targeted therapies, long-term efficacy is not possible because acquired drug resistance hampers the effectiveness of these therapies. We found that a fiber inspired smart scaffold (FiSS) platform established in our laboratory allows growth of …

Construction Of G-Quadruplexes Via Self-Assembly: Enhanced Stability And Unique Properties, Ying He

USF Tampa Graduate Theses and Dissertations

This dissertation mainly contains three parts: 1) The construction of well-defined G8-octamers through the monomer conformational design. 2) The construction of cross-layer interactions in the G8-octamer for enhanced stability in H-bond competitive solvents. 3) Design and synthesis of 8-triazole guanosine with photoluminescent properties.

Through the structural conformational design, we have developed a new class of guanosine derivatives with modification on guanine (8-aryl) and ribose (2’,3’-isopropylidene). This unique design has led to the formation of the first discrete G8-octamer with structure characterized by NMR, MS and single crystal X-ray diffraction. The selectivity between monovalent (K+) and divalent cat-ions (Ba2+ and Sr2+) …

Cordycepin Inhibits Human Ovarian Cancer By Inducing Autophagy And Apoptosis Through Dickkopf-Related Protein 1/Β-Catenin Signaling, Hyun-Jin Jang, Kyeong Eun Yang, In-Hu Hwang, Yang Hoon Huh, Dae Joon Kim, Hwa-Seung Yoo, Soo Jung Park, Ik-Soon Jang

School of Medicine Publications

Cordycepin, the major active component from Cordyceps militaris, has been reported to significantly inhibit some types of cancer; however, its effects on ovarian cancer are still not well understood. In this study, we treated human ovarian cancer cells with different doses of cordycepin and found that it dose-dependently reduced ovarian cancer cell viability, based on Cell counting kit-8 reagent. Immunoblotting showed that cordycepin increased Dickkopf-related protein 1 (Dkk1) levels and inhibited β-catenin signaling. Atg7 knockdown in ovarian cancer cells significantly inhibited cordycepin-induced apoptosis, whereas β-catenin overexpression abolished the effects of cordycepin on cell death and proliferation. Furthermore, we found …

Innovating Green Stormwater Infrastructure For Nutrient Management: Long-Term Field And Modeling Studies Of Conventional And Modified Denitrifying Bioretention Systems, Emma V. Lopez-Ponnada

USF Tampa Graduate Theses and Dissertations

Urban stormwater and nutrient management are increasingly important topics to address globally, as coastal urbanization increases, disturbing the natural landscape, hydrology, and water quality. Untreated urban stormwater runoff carries pollutants that enter our waterways, such as rivers and marine environments, which serve as drinking water sources, recreational sites, and locations for economic livelihood. One pollutant and nutrient of concern for water quality is reactive nitrogen (N). Since pre-industrial time, reactive nitrogen has doubled from human activity. When found in excess in waterways, nitrogen causes an overabundant growth of algae, which can result in eutrophic and hypoxic conditions, impacting ecosystems, human …

The Peculiar Nature Of Florida’S Sandhill Wetlands, Ponds & Lakes— Their Ecohydrology, Relationship With The Regional Aquifer & Importance Within The Landscape., Renae Starr Nowicki

USF Tampa Graduate Theses and Dissertations

This dissertation explores the ecohydrology of Florida’s peculiar and poorly studied sandhill wetland and water features, particularly those located in west-central Florida. The primary research goals include: compilation and summarization of the available ecohydrologic information for features across Florida; comparison of water level and water geochemistry data between sandhill wetlands and waters and the regional aquifer to provide evidence of regional hydrologic control; and use of geophysical applications to examine the hydraulic connections between sandhill wetlands and waters and the regional aquifer.

From this research, a natural history of sandhill wetland and water ecohydrology is presented, highlighting: the differences between …

Constituent Partitioning Consensus Docking Models And Application In Drug Discovery, Rainer Metcalf

USF Tampa Graduate Theses and Dissertations

This work expounds on some of the current computational tools and programs available and the best practices associated with their use. A high-level introduction, intended for both novices and the semi-experienced, focusing on the more common programs used in scientific literature is the scope of this topic. Both classical and quantum techniques are described. Classical methodologies include Molecular Dynamics, Monte Carlo, energy minimization methods, molecular docking, low-mode, and homology modeling. Quantum chemistry techniques are also discussed encompassing Hartree-Fock, Post-Hartree-Fock theories, and Density Functional Theory along with associated basis sets.

Along with established methodologies, novel theoretical methods are introduced for furthering …

Development Of A Voxel-Based Monte Carlo Radiation Dosimetry Methodology For A Targeted Alpha Particle Therapy, Christopher John Tichacek

USF Tampa Graduate Theses and Dissertations

The use of targeted ligands to deliver radioisotopes directly to tumor cells is a promising therapeutic strategy. Because of the short path length and high LET of alpha particles, targeted alpha particles are ideal for treating metastatic disease while minimizing damage to non-targeted tissues. However, clinical methods for determining 3D radiation dosimetry in patients with multiple metastatic lesions are needed to support clinical translation of novel targeted alpha particle therapies for personalized treatment, especially in patients that have previously received radiotherapy. Recently interest in novel radiopharmaceutical development has grown significantly. However, compared to external beam radiation therapy, progress in customizing …

Hierarchical Conjugated Polymer Systems Prepared By Controlled Chain-Growth Polymerization, Chunwa Peter Kei

LSU Doctoral Dissertations

π-Conjugated polymer materials may have a significant economic impact on society by providing means for designing affordable, flexible, and portable organic electronic devices. Their successful commercialization will depend on major scientific advancements, which will challenge human society to seek out ever more detailed and fundamental processes to command. Controlled polymerization affords such a power; allowing for the design of meticulous and precisely defined systems granting detailed insight into structure-property relationships in the polymer materials and bettering understanding of novel physical phenomena.

This dissertation primarily focuses on development and preparation of well-defined hierarchically organized macromolecular systems. The novel chain-growth polymerization methodologies …

Software Design For Probabilistic Safety: Stochastic Reachability And Circadian Control, Joseph D. Gleason

Electrical and Computer Engineering ETDs

Stochastic reachability is an important verification tool that provides probabilistic assurances of safety in a variety of contexts. In engineered systems, safety may be synonymous with the ability of the system to avoid "bad" constraints on the state space, that constitute collision, departure from a flight envelope, or other undesirable phenomenon. In biomedical systems, assurance of safety (such as the mandate to ``do no harm'') are considerably complicated by the fact that there is a lack of physics-driven models, extensive signal processing is needed to capture the underlying state of the system, and the stochasticity inherent to the system may …

Molluscum Contagiosum Infection With Features Of Primary Cutaneous Anaplastic Large Cell Lymphoma., Doaa Shalabi, John Ringe, Jason B. Lee, Neda Nikbakht

Department of Dermatology and Cutaneous Biology Faculty Papers

CD30+ T cell pseudolymphomas (CD30+ PSL) are a group of benign inflammatory cutaneous disorders that can develop in settings of viral infections or drug reactions. Owing to their histological similarities to malignant lymphomas, these benign infiltrates are occasionally misdiagnosed as malignant, causing significant concerns for patients and physicians. Herein, we report a patient with CD30+ PSL associated with molluscum contagiosum whose initial biopsy revealed atypical large CD30-expressing cells, leading to a misdiagnosis of primary cutaneous anaplastic large cell lymphoma and referral to our cutaneous lymphoma clinic. We report this case to demonstrate that reactive CD30+ infiltrate associated with molluscum contagiosum …

November Agenda, Wku Graduate Council

Graduate School

Meeting agenda

Evaluation Of Soil Type And Seeding Rate On Winter Cover Crop Species In A Soybean Production System, Donna S. Morgan

LSU Doctoral Dissertations

The integration of winter annual cover crops into a cropping system can potentially improve soil health and crop production, however, the impact of variables such as seeding rates, across two very different soil types, has not been well documented. A two-year study was conducted at the Dean Lee Research Station and Extension Center in Alexandria, Louisiana to evaluate the effects of cover crop seeding rate and soil type on cover crop biomass, weed suppression, soil fertility, and soybean (Glycine max L) growth and yield. Analysis of potential economic impacts was also performed to estimate financial net returns for three …