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Element 6 Chairs And Course List Core General Education Assessment, 2018-2019, Undergraduate Core Oversight Committee, Wright State University

Core General Education Assessments - All

The Chairs and Course List for Element 6 - Natural Science as part of the institution’s ongoing general education Core assessment plan.

The Wright State – Lake Campus 2018 – 2019 Scholarly Review, Wright State University - Lake Campus

Lake Campus Research Symposium Reports

This report provides a listing of the scholarly endeavors from Lake Campus during the 2018 calendar year spanning across disciplines.

This document contains the Annual Research Report from 2018 and the Research Symposium Program from 2019.

Effect Of Administration Of Somatostatin Analogue On Blood Pressure In Chronic Intermittent Hypoxic Rats, Kajal Kamra

Browse all Theses and Dissertations

The cardiorespiratory system in our bodies does not adapt to Chronic Intermittent Hypoxia (CIH) and consequently syndromes such as sleep apnea lead to pathophysiological conditions like Hypertension. It has been demonstrated that the peripheral chemoreceptors underpin the development of these conditions and at present, there are no selective drug therapies for this form of hypertension. However, evidence suggests that peripheral chemoreflex sensitivity to CO2 & hypoxia is reduced by Somatostatin (SST) in humans. Our preliminary in-vitro studies have demonstrated that SST will blunt the response of the carotid body to hypoxia and decrease the baseline activity of the carotid body. …

Preference, Performance, And Selection Of Historic And Novel Hosts By Emerald Ash Borer, Agrilus Planipennis Fairmaire (Coleoptera: Buprestidae), Donnie L. Peterson

Browse all Theses and Dissertations

North American and European ash trees are highly susceptible to emerald ash borer (EAB, Agrilus planipennis). This buprestid kills hosts via larva feeding on vascular tissue which eventually kills the host plant. Two new hosts have recently been found to support larval development of EAB. White fringetrees (Chionathus virginicus) were found attacked by EAB in 2014 and since then have been found to be attacked throughout other parts of the United States, while olive (Olea europaea) has only experimentally been found to support larvae to adulthood. Chemical profiles of these two plants were collected and analyzed to determine how their …

Determination Of Benzotriazole And Analog Compounds By Liquid Chromatography-Mass Spectrometry In Surface Runoff Water Samples From Wilmington Air Park, Jessica A. Wiese

Browse all Theses and Dissertations

Benzotriazole (BTri) and its analog compounds are widely used in aircraft de-icing and anti-icing solutions, however their high solubility in water and resistance to biodegradation results in only their partial removal in wastewater treatment, and therefore makes them potential contaminants in watershed systems. The Wilmington Air Park in Wilmington, Ohio currently has two surface-runoff lagoons to pre-treat water containing these de-icing compounds before releasing it into nearby streams. Because the Wilmington Air Park has recently made an agreement with a major online retailer to lease over two dozen planes and open a package-sorting facility beginning in late 2019, the goal …

Mitochondria-Dependent Cellular Toxicity Of Α-Synuclein Modeled In Yeast, Rajalakshmi Santhanakrishnan

Browse all Theses and Dissertations

Parkinson’s disease is the second most common neurodegenerative disease. This disease is caused by the degeneration of dopaminergic neurons, leading to debilitating motor symptoms and early mortality. The protein α-synuclein (α-syn), encoded by SNCA, misfolds and forms inclusions in Parkinson’s disease brains. When α-syn is overexpressed in yeast, it causes cellular toxicity and an increased number of aggregates, recapitulating the toxic phenotypes observed in humans and animal models. Yeast models are a powerful tool to perform high-throughput overexpression screening to identify modifiers of α-syn toxicity. α-syn causes mitochondrial dysfunction by inhibiting complex I and inducing mitochondrial fragmentation. Prior screening of …

Distribution And Population Status Of Nesting Reddish Egrets (Egretta Rufescens) In Florida, W. Andrew Cox, Amy Schwarzer, Richard Kiltie, Ann Paul, Mark Rachal, Gina M. Kent, Kenneth D. Meyer, Jerome J. Lorenz

Florida Field Naturalist

No abstract provided.

2019 Associate's Degree Exit Survey, Southwestern Oklahoma State University

Assessment Center Reports

Exit Surveys produced by the SWOSU Assessment Center.

Author Instructions, Marine Ornithology

Marine Ornithology

No abstract provided.

Masthead, Marine Ornithology

Marine Ornithology

No abstract provided.

Kiaa1549-Braf Expression Establishes A Permissive Tumor Microenvironment Through Nfκb-Mediated Ccl2 Production, Ran Chen, Chanel Keoni, Christopher A. Waker, Robert M. Lober, Robert M. Lober, Yihsien Chen, David H. Gutmann

Pediatrics Faculty Publications

KIAA1549-BRAF is the most frequently identified genetic mutation in sporadic pilocytic astrocytoma (PA), creating a fusion BRAF (f-BRAF) protein with increased BRAF activity. Fusion-BRAF-expressing neural stem cells (NSCs) exhibit increased cell growth and can generate glioma-like lesions following injection into the cerebella of naïve mice. Increased Iba1+ monocyte (microglia) infiltration is associated with murine f-BRAF-expressing NSC-induced glioma-like lesion formation, suggesting that f-BRAF-expressing NSCs attract microglia to establish a microenvironment supportive of tumorigenesis. Herein, we identify Ccl2 as the chemokine produced by f-BRAF-expressing NSCs, which is critical for creating a permissive stroma for gliomagenesis. In addition, f-BRAF regulation of Ccl2 production …

Spatial Conservation Planning Under Uncertainty: Adapting To Climate Change Risks Using Modern Portfolio Theory, Mitchell J. Eaton, Simeon Yurek, Zulqarnain Haider, Julien Martin, Fred A. Johnson, Bradley J. Udell, Hadi Charkhgard, Changhyun Kwon

United States Geological Survey: Staff Publications

Climate change and urban growth impact habitats, species, and ecosystem services. To buffer against global change, an established adaptation strategy is designing protected areas to increase representation and complementarity of biodiversity features. Uncertainty regarding the scale and magnitude of landscape change complicates reserve planning and exposes decision makers to the risk of failing to meet conservation goals. Conservation planning tends to treat risk as an absolute measure, ignoring the context of the management problem and risk preferences of stakeholders. Application of risk management theory to conservation emphasizes the diversification of a portfolio of assets, with the goal of reducing the …

The Extension Newsletter, Issue 100, Winter 2019, Wright State University Retirees Association

The Extension Newsletter

An eight page newsletter from the Wright State University's Retirees Association.

A Psychosocial Behavioral Attribution Model: Examining The Relationship Between The “Dark Triad” And Cyber-Criminal Behaviors Impacting Social Networking Sites, Kim Withers

CCAC Theses and Dissertations

This study proposes that individual personality characteristics and behavioral triggering effects come together to motivate online victimization. It draws from psychology’s current understanding of personality traits, attribution theory, and criminological research. This study combines the current computer deviancy and hacker taxonomies with that of the Dark Triad model of personality mapping. Each computer deviant behavior is identified by its distinct dimensions of cyber-criminal behavior (e.g., unethical hacking, cyberbullying, cyberstalking, and identity theft) and analyzed against the Dark Triad personality factors (i.e., narcissism, Machiavellianism, and psychopathy). The goal of this study is to explore whether there are significant relationships among the …

Adaptive Strategies Of Multi-Objective Optimization For Greener Networks, Hatem Yazbek

CCAC Theses and Dissertations

Increasing energy costs and environmental issues related to the Internet and wired networks continue to be a major concern. Energy-efficient or power-aware networks continue to gain interest in the research community. Existing energy reduction approaches do not fully address all aspects of the problem. We consider the problem of reducing energy by turning off network links, while achieving acceptable load balance, by adjusting link weights. Changing link weights frequently can cause network oscillation or instability in measuring the resulting traffic load, which is a situation to be avoided. In this research, we optimize two objectives, which are minimizing network power …

Constructing The Pluriverse: Lessons Learned Thus Far, Bernd Reiter

School of Interdisciplinary Global Studies Faculty Publications

No abstract provided.

Habitat Characteristics And Nesting Success Of The Western Burrowing Owl In A Suburban Desert Landscape, Kerrie Anne T. Loyd, Rhiannon T. Watkins

Arizona Birds

Burrowing Owls (Athene cunicularia) are a species of conservation concern in most western states. In Lake Havasu City, Arizona, owls are common in desert washes in developed suburban and urban locations. These vegetated and steeply sloping washes host dozens of breeding pairs of owls. Suburban wash habitats may offer benefits such as a larger and more diverse prey base (due to additional and varied vegetation), perch sites, and existing burrows compared to washes in natural areas.. However, suburban owl populations are susceptible to secondary poisoning, predation, and disturbance from construction. This project examined habitat preferences and reproductive success of Burrowing …

Impact Of Self-Determined Motivation On Work Behavior And Response To Cognitive Remediation In Individuals With Schizophrenia, Desmond Spann

All Graduate Theses, Dissertations, and Other Capstone Projects

Research has implicated motivational deficits as having a severe impact on functional outcomes and quality of life for individuals with schizophrenia. There has been a call for investigation on how these motivational deficits impact different aspects of the therapeutic process for these individuals. A popular model of motivation used in recent investigation with schizophrenia has been Self-Determination Theory. This theory tries to describe why individuals undertake specific goals and behaviors, with the focus being the content of goal-directed outcomes and the regulatory processes with which outcomes are pursued. The goal of this investigation is to examine the impact of self-determined …

Perceived Child Regard, Parenting Stress, And Depressive Symptoms Of Nonresidential And Residential Stepmothers, Lenee Nicole Kehnt, Magy Martin, Don Martin

Walden Faculty and Staff Publications

An analysis of covariance was used to determine whether differences existed between nonresidential and residential stepmothers regarding parental stress, perceived parental regard, and depressive symptoms. The participants selected for the study were both nonresidential and residential stepmothers, 18 years and older. Participants completed a web-based survey that administered three different instruments: The Perceived Child Regard Questionnaire, the Parental Stress Scale, and the Center for Epidemiologic Studies Depression Scale-Revised. A total sample size of 94 nonresidential stepmothers and 79 residential stepmothers completed the survey. Results indicated no significant differences in parental stress and depressive symptoms due to custody status. However, there …

Effects Of Pag1 On Src-Family Kinase Trafficking In Neuroblastoma Cells, Makenzie E. Mayfield

Undergraduate Theses, Professional Papers, and Capstone Artifacts

The receptor tyrosine kinases (RTKs) are known to help regulate cell behaviors including differentiation, proliferation and migration during embryonic development of the neural crest. RTKs are believed to initiate signaling cascades in response to extracellular cues in part by controlling localization of Src-family kinases (SFKs). The scaffolding protein PAG1 binds SFKs and is believed to influence SFK activity and location within the cell by promoting interaction of SFKs with regulatory proteins and by drawing SFKs into different components of the endocytic pathway. By targeting the PAG1 gene in SH-SY5Y neuroblastoma cells with CRISPR/Cas9 plasmids, we created PAG1-mutant cell-lines in which …

Bachelor Of Science-Biology 2019-2020, Nova Southeastern University

Undergraduate Programs Course Catalogs

No abstract provided.

The Current Volume 30 : Issue 11, Nova Southeastern University

Student Newspapers

Homecoming Edition

Introducing the new Razor

Tar Wars: Oil, Environment And Alberta's Image, By Geo Takach, Gordon Alley-Young

Publications and Research

No abstract provided.

Next-Generation Sequencing Of Hiv-1 Single Genome Amplicons, Gustavo H. Kijak, Eric Sanders-Buell, Phuc Pham, Elizabeth A. Harbolick, Celina Oropeza, Anne Marie O'Sullivan, Meera Bose, Charmagne G. Beckett, Mark Milazzo, Merlin L. Robb, Sheila A. Peel, Paul T. Scott, Nelson L. Michael, Adam W. Armstrong, Jerome H. Kim, David Brett-Major, Sodsai Tovanabutra

Journal Articles: Epidemiology

The analysis of HIV-1 sequences has helped understand the viral molecular epidemiology, monitor the development of antiretroviral drug resistance, and design candidate vaccines. The introduction of single genome amplification (SGA) has been a major advancement in the field, allowing for the characterization of multiple sequences per patient while preserving linkage among polymorphisms in the same viral genome copy. Sequencing of SGA amplicons is performed by capillary Sanger sequencing, which presents low throughput, requires a high amount of template, and is highly sensitive to template/primer mismatching. In order to meet the increasing demand for HIV-1 SGA amplicon sequencing, we have developed …

De Novo Assembly Of The Brugia Malayi Genome Using Long Reads From A Single Minion Flowcell, Joseph R. Fauver, John Martin, Gary J. Weil, Makedonka Mitreva, Peter U. Fischer

Journal Articles: Epidemiology

Filarial nematode infections cause a substantial global disease burden. Genomic studies of filarial worms can improve our understanding of their biology and epidemiology. However, genomic information from field isolates is limited and available reference genomes are often discontinuous. Single molecule sequencing technologies can reduce the cost of genome sequencing and long reads produced from these devices can improve the contiguity and completeness of genome assemblies. In addition, these new technologies can make generation and analysis of large numbers of field isolates feasible. In this study, we assessed the performance of the Oxford Nanopore Technologies MinION for sequencing and assembling the …

11. Rudolf Stefan Weigl (Exhibit Panel - Doctors And Nurses As Rescuers In Humanitarian Crises), Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

This file is the "Rudolf Stefan Weigl" panel, which is a part of the exhibit entitled "Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition" shown at the Grout Museum in Waterloo, Iowa in 2019 and 2020.

To see the supplemental information, click the Related Work button.

05. Bodil Katharine Biørn Supplemental Information, Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

Supplemental information for the Bodil Katharine Biørn exhibit panel.

To see the associated exhibit panel, click the Related Work button.

11. Rudolf Stefan Weigl Supplemental Information, Stephen Gaies

Doctors and Nurses as Rescuers in Humanitarian Crises Exhibition

Supplemental information for the Rudolf Stefan Weigl exhibit panel.

To see the associated exhibit panel, click the Related Work button.

The "Evergreening" Metaphor In Intellectual Property Scholarship, Erika Lietzan

Faculty Publications

This article is a plea for changes in the scholarly dialogue about "evergreening" by drug companies. Allegations that drug companies engage in "evergreening" are pervasive in legal scholarship, economic scholarship, medical and health policy scholarship, and policy writing, and they have prompted significant policymaking proposals. This Article was motivated by concern that the metaphor has not been fully explained and that policymaking in response might therefore be premature. It canvasses and assesses the scholarly literature-more than 300 articles discussing or mentioning "evergreening." It catalogues the definitions, the examples, and the empirical studies. Scholars use the term when describing certain actions …

Learning And The Practice Of Social Media In Informal Science Education Centers, Lisa Lundgren, Kent J. Crippen

Instructional Technology and Learning Sciences Faculty Publications

Both social media and informal learning spaces have the potential to foment knowledge-building. This article aims to bridge theory and practice with an analysis of the social media practices across informal science learning centers through the lens of the Contextual Model of Learning. We evaluate strategies through directed content analysis of phone interviews, online surveys, and researcher field notes. Our findings reveal that informal science learning centers create marketing-related social media strategies as opposed to ones which align with contemporary learning in informal settings. Implications for researchers who seek to use social media in an educative manner are discussed.