Digital Commons Network^™

Clinical Research In Pneumonia: Role Of Artificial Intelligence, Timothy L. Wiemken, Robert R. Kelley, William A. Mattingly, Julio A. Ramirez

The University of Louisville Journal of Respiratory Infections

No abstract provided.

The Latin-American Flavor Of Enforced Disappearances, Ariel E. Dulitzky

Chicago Journal of International Law

Enforced disappearances occur when persons are deprived of their liberty by state officials, organized groups, or private individuals acting on behalf of, or with the support, direct or indirect, consent, or acquiescence of the government. The deprivation of liberty is followed by a refusal to disclose the fate or whereabouts of the persons concerned or a refusal to acknowledge the deprivation of their liberty. Consequently, such persons are placed outside the protection of the law. As such, the crime and the human rights violation of enforced disappearance comprise many different types of state repression. Given this multiplicity of scenarios in …

Lncegfl7os Regulates Human Angiogenesis By Interacting With Max At The Egfl7/Mir-126 Locus, Quinbo Zhou, Chastain Anderson, Zhan-Peng Huang, Jakub Hanus, Wensheng Zhang, Yu Han

Faculty and Staff Publications

In an effort to identify human endothelial cell (EC)-enriched lncRNAs,~500 lncRNAswere shown to be highly restricted in primary human ECs. Among them,lncEGFL7OS, located inthe opposite strand of theEGFL7/miR-126gene, is regulated by ETS factors through abidirectional promoter in ECs. It is enriched in highly vascularized human tissues, and upregulatedin the hearts of dilated cardiomyopathy patients. LncEGFL7OS silencing impairs angiogenesis asshown by EC/fibroblast co-culture, in vitro/in vivo and ex vivo human choroid sproutingangiogenesis assays, while lncEGFL7OS overexpression has the opposite function. Mechanistically,lncEGFL7OS is required for MAPK and AKT pathway activation by regulating EGFL7/miR-126expression. MAX protein was identified as a lncEGFL7OS-interacting protein that …

Prediction Of Ice-Free Conditions For A Perennially Ice-Covered Antarctic Lake, M. K. Obryk, P. T. Doran, J. C. Priscu

Faculty Publications

©2019. American Geophysical Union. All Rights Reserved. Although perennially ice-covered Antarctic lakes have experienced variable ice thicknesses over the past several decades, future ice thickness trends and associated aquatic biological responses under projected global warming remain unknown. Heat stored in the water column in chemically stratified Antarctic lakes that have middepth temperature maxima can significantly influence the ice thickness trends via upward heat flux to the ice/water interface. We modeled the ice thickness of the west lobe of Lake Bonney, Antarctica, based on possible future climate scenarios utilizing a 1D thermodynamic model that accounts for surface radiative fluxes as well …

The Underdeveloped Innate Immunity In Embryonic Stem Cells: The Molecular Basis And Biological Perspectives From Early Embryogenesis, Yan-Lin Guo

Faculty Publications

Embryonic stem cells (ESCs) have been intensively studied as a promising cell source for regenerative medicine. The rapid advancements in the field have not only proven the feasibility of ESC‐based cell therapy, but also led to a better understanding of pluripotent stem cells (PSCs) as a unique cell population at an early stage of embryogenesis. Recent studies have revealed that both human and mouse ESCs have attenuated innate immune responses to infectious agents and inflammatory cytokines. These findings raise interesting questions about the rationale for ESCs, the PSCs experimentally derived from preimplantation stage embryos, to not have an innate defense …

Strengthening Healthy Work Environments For Nursing Faculty Through An Evidence-Based Academic Nurse Residency Program, Elizabeth A. Gazza, Melissa G. Mehrlich

Creating Healthy Work Environments (CHWE)

The purpose of this presentation is to propose an evidence-based academic nurse residency program designed to support nurses transitioning to the faculty role. This interactive session will be beneficial faculty, administrators, nurses interested in the faculty role, and those who prepare nurse educators.

Attachment And Relationship Quality: A Longitudinal Cross-Lagged Panel Model Examining The Association Of Attachment Styles And Relationship Quality In Married Couples, Meagan Cahoon Alder

Theses and Dissertations

This is a longitudinal cross-lagged panel model examining the bi-directional association of attachment styles and relationship quality in a community sample of 355 married couples, with at least one child between 10-14 years of age at the beginning of the study and 17-21 years of age at the end of the study. An Actor-Partner Interdependence Model (APIM), was used to test for actor and partner effects, thereby accounting for the non-independent nature of the data. Two separate APIM models were tested with Male Attachment predicting Female Relationship Quality and Female Attachment predicting Male Relationship Quality. Results indicate that own attachment …

A Scientometric Look At Mathematics Education From Scopus Database, Miguel Cruz Ramirez, Rafael Armando Rodriguez Devesa

The Mathematics Enthusiast

The present work offers a characterization of the development of mathematics education, based on scientometric indicators. The study analyzes 5633 documents registered in the Scopus database which are all related to research in mathematics education. The main results show an exponential increase on the scientific productivity, a tendency to increase collaborative work over individual work, a greater impact per index of the cited references during the last two decades, a high level of international collaboration, a certain concentration of the publications on a reduced group of investigators in some international impact journals, and the existence of 17 invisible colleagues that …

A Mathematical Analysis Of Student-Generated Sorting Algorithms, Audrey Nasar

The Mathematics Enthusiast

Sorting is a process we encounter very often in everyday life. Additionally it is a fundamental operation in computer science. Having been one of the first intensely studied problems in computer science, many different sorting algorithms have been developed and analyzed. Although algorithms are often taught as part of the computer science curriculum in the context of a programming language, the study of algorithms and algorithmic thinking, including the design, construction and analysis of algorithms, has pedagogical value in mathematics education. This paper will provide an introduction to computational complexity and efficiency, without the use of a programming language. It …

Girls Explore Math Careers By Making 3d-Constructions Of Diverse Women Mathematicians’ Lives, Audrey C. Rule, Dana Atwood Blaine, Clayton M. Edwards, Mindy Gordon

The Mathematics Enthusiast

Few women and minorities work in STEM areas, making urgent appropriate role models, cultural barrier education, and growth mindset development. This study focused on a diverse group of 24 fifth grade girls at an urban school learning about successful mathematical careers of contemporary women of different races. Students viewed illustrated slide shows of the women’s lives and accomplishments, discussing their jobs and barriers they overcame. Students gained spatial skills constructing dioramas of the women’s lives and careers. Thematic analysis of student responses to questionnaires and sentences from reflection essays revealed aspects of a mathematician’s life and work that allowed students …

Fabrication Of Pomegranate Peel Extract/Honey Nanofibers Loaded With Bee Venom As Effective Antibacterial Wound Dressings, Sara Abouzekry

Theses and Dissertations

In spite of the emerging advances in the field of wound dressings, there is still a deep need for the development of novel natural based dressings to offer a safe alternative for traditional wound dressings and most importantly fight against antibacterial resistance. The aim of this study is to develop novel honey based nanofibrous wound dressing for achieving both effective and safe treatment and investigate the dressings for antibacterial activity, cytotoxicity and in vivo wound healing effect in a rat wound model. Natural products; Honey, Pomegranate peel extract (PPP), and bee venom (BV), known for their antibacterial and anti-inflammatory properties, …

Assessing The Resilience Of Adolescents Who Were Raised In Orphanages In Cairo, Egypt, Noha Emam Hassanin

Theses and Dissertations

Orphans in Egypt face discrimination at school, in the work place and when finding a marriage partner. They also are at risk for developing physical, emotional and intellectual delays as a result of residing in an orphanage. The small amount of research conducted on orphans in Egypt has focused on these deficits and the hardships. However, it may be more empowering and more effective to focus on the strengths and capabilities of these youth. In particular, during adolescence when Egyptian orphans must leave their institutions, it is especially important to understand how to support resilience and give them the tools …

Users' Obstacles To Ict Adoption In Egyptian Construction Companies., Ahmed Azzam

Theses and Dissertations

Construction companies often face resistance from some employees when adopting a new Information and Communication Technology “ICT” at the workplace. Technology Acceptance Models in the literature indicated the factors affecting the employees’ behavior. However, none of these models were applied in the Egyptian Construction Industry context to test their validity. In this thesis, 10 factors were collected from different Technology Acceptance models and their validity were tested in the Egyptian Construction Industry context through questionnaires survey. The behavior of employees in Egyptian Construction companies was validated to be consistent with the described behavior in the literature. The 10 factors were …

God Likes Sex: Conversations Integrating Spirituality And Sexuality, Jennie Armstrong

Doctor of Ministry

Throughout Christian history, the Church has provided inconsistent messages about the spiritual foundation for healthy sexuality. With avoidant messages of silence and shame around sexual topics from the Church, many emergent women separate their spirituality from their sexual lives, never considering scripture as a guideline for healthy sexuality. Emergent adult women, specifically those without strong spiritual foundations, are more likely to engage in unhealthy sexual behaviors which often leave them feeling alone and separate from God and spiritual community. Because popular culture does not support marriage as a moral requirement for a sexual relationship, present cultural messages advocate that these …

Soul Journey: Rediscovering The Sacred Paths For Body, Heart, And Mind, Christopher Fillingham

Doctor of Ministry

The spiritually thirsty are leaving the church in the West. They do not find the church to be a place of spiritual wisdom and nourishment. This dissertation follows various ancient guides within Christianity to recover a life-giving spirituality for the Western Church in the twenty-first century. Chapter 1 draws on the desert monastics as it explores the lack of a transformational spirituality in the modern Church. It defines spirituality in terms of eros, clarifies the aim of spirituality as union, and explores the common reductions that have led the Church astray. Chapter 2 connects the three spiritual paths outlined in …

Carbohydrate Polymers As Controlled Release Devices For Pesticides, Soma Chakraborty, Maria Cleofe Neri-Badang

Chemistry Faculty Publications

Controlled release technology addresses problems associated with excessive use of toxic agricultural chemicals. This paper reviews the studies on the use of carbohydrate polymers as controlled release matrices for pesticides. Alginates, starch and its derivatives, chitosan, carboxymethylcellulose and ethylcellulose are some of the natural polymers discussed in this review. The advantages and disadvantages of these polymeric systems as well as the factors that affect pesticide release are presented. A discussion on the polymers’ encapsulation efficiency and release profile is also included, which will aid future researchers in identifying the suitable formulation for controlled release of pesticides. Combination of two polymers, …

2019 Report To The General Assembly: Nursing Home Inspection And Enforcement Activities, Tennessee. Department Of Health.

Nursing Home Inspection and Enforcement Activities Report

No abstract provided.

Deficit Irrigation Management Of Maize In The High Plains Aquifer Region: A Review, Daran Rudnick, Sibel Irmak, C. West, J.L. Chavez, I. Kisekka, T.H. Marek, J.P. Schneekloth, D. Mitchell Mccallister, V. Sharma, K. Djaman, J. Aguilar, M.E. Schipanski, D.H. Rogers, A. Schlegel

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Irrigated agriculture is a major economic contributor of the High Plains Region and it primarily relies on the High Plains Aquifer as a source of water. Over time, areas of the High Plains Aquifer have experienced drawdowns limiting its ability to supply sufficient water to sustain fully irrigated crop production. This among other reasons, including variable climatic factors and differences in state water policy, has resulted in some areas adopting and practicing deficit irrigation management. Considerable research has been conducted across the High Plains Aquifer region to identify locally appropriate deficit irrigation strategies. This review summarizes and discusses research conducted …

Secreted Frizzled Related Protein Is A Target Of Paxb And Plays A Role In Aquiferous System Development In The Freshwater Sponge, Ephydatia Muelleri, Chelsea Hall, Melanie Rodriguez, Josephine Garcia, Dora Posfai, Rachel Dumez, Erik Wictor, Omar A. Quintero, Malcolm Hill, Ajna S. Rivera, April L. Hill

All Faculty Scholarship

Canonical and non-canonical Wnt signaling, as well as the Pax/Six gene network, are involved in patterning the freshwater sponge aquiferous system. Using computational approaches to identify transcription factor binding motifs in a freshwater sponge genome, we located putative PaxB binding sites near a Secreted Frizzled Related Protein (SFRP) gene in Ephydatia muelleri. EmSFRP is expressed throughout development, but with highest levels in juvenile sponges. In situ hybridization and antibody staining show EmSFRP expression throughout the pinacoderm and choanoderm in a subpopulation of amoeboid cells that may be differentiating archeocytes. Knockdown of EmSFRP leads to ectopic oscula formation during development, suggesting …

Quantifying Proliferative And Surface Marker Heterogeneity In Colony‐Founding Connective Tissue Progenitors And Their Progeny Using Time‐Lapse Microscopy, Edward Kwee, Gerald M. Saidel, Kimerly Powell, Christopher M. Heylman, Cynthia A. Boehm, George F. Muschler

Biomedical Engineering

Connective tissue progenitors (CTPs) are defined as the heterogeneous population of tissue‐resident stem and progenitor cells that are capable of proliferating and differentiating into connective tissue phenotypes. The prevalence and variation in clonal progeny of CTPs can be characterized using a colony formation assay. However, colony assays do not directly assess the characteristics of the colony‐founding CTP. We performed large, field‐of‐view, time‐lapse microscopy to manually track colonies back to the founding cells. Image processing and analysis was used to characterize the colonies and their founding cells. We found that the traditional colony‐forming unit (CFU) assay underestimates the number of founding …

Functional Gastrointestinal Disorders And Gut-Brain Axis: What Does The Future Hold?, Kashif Mukhtar, Hasham Nawaz, Shahab Abid

Section of Gastroenterology

Despite their high prevalence, lack of understanding of the exact pathophysiology of the functional gastrointestinal disorders has restricted us to symptomatic diagnostic tools and therapies. Complex mechanisms underlying the disturbances in the bidirectional communication between the gastrointestinal tract and the brain have a vital role in the pathogenesis and are key to our understanding of the disease phenomenon. Although we have come a long way in our understanding of these complex disorders with the help of studies on animals especially rodents, there need to be more studies in humans, especially to identify the therapeutic targets. This review study looks at …

The Emergence Of The Environmental Impact Assessment Duty As A Global Legal Norm And General Principle Of Law, Tseming Yang

UC Law Journal

More than half a century ago, Rudolf Schlesinger announced a global survey of legal principles in the pages of the American Journal of International Law. The project’s objective was the identification of a “common core” of legal norms among the family of nations and the ultimate goal the production of something akin to a global restatement of law. Such an endeavor was to yield global principles of law, ultimately giving substance to the General Principles of Law provision under Article 38 of the Statute of the International Court of Justice. In spite of the initial enthusiasm surrounding the project, its …

Perceptions Of Elementary School Parents, Principals, And School Resource Officers Regarding Visitor Management Systems And School Safety, Janalee Olhausen-Kaylor

Dissertations

Currently, three out of 10 parents fear for their students’ safety while attending classes within the public school setting (McCarthy, 2015). This study focused on two elements that directly affect safety within schools: visitor management and intruder prevention. To analyze each of these two elements, qualitative methodology was utilized through four focus groups to determine the perceptions of Elementary school administrators, parents, and school resource officers on school safety. After conducting multiple interviews, four common themes emerged. The first theme was monitoring access to school buildings. Participants asserted taking an active approach in this area would increase the overall safety …

4-D Computational Modeling Of Cardiac Outflow Tract Hemodynamics Over Looping Developmental Stages In Chicken Embryos, Katherine Courchaine, Mackenzie J. Gray, Kaitlin Beel, Kent L. Thornburg, Sandra Rugonyi

OHSU-PSU School of Public Health Faculty Publications and Presentations

Cardiogenesis is interdependent with blood flow within the embryonic system. Recently, a number of studies have begun to elucidate the effects of hemodynamic forces acting upon and within cells as the cardiovascular system begins to develop. Changes in flow are picked up by mechanosensors in endocardial cells exposed to wall shear stress (the tangential force exerted by blood flow) and by myocardial and mesenchymal cells exposed to cyclic strain (deformation). Mechanosensors stimulate a variety of mechanotransduction pathways which elicit functional cellular responses in order to coordinate the structural development of the heart and cardiovascular system. The looping stages of heart …

Viscosities, Diffusion Coefficients, And Mixing Times Of Intrinsic Fluorescent Organic Molecules In Brown Limonene Secondary Organic Aerosol And Tests Of The Stokes–Einstein Equation, Dagny A. Ullmann, Mallory L. Hinks, Adrian M. Maclean, Christopher Butenhoff, James W. Grayson, Kelley Barsanti, Jose L. Jimenez, Sergey A. Nizkorodov, Saeid Kamal, Allan K. Bertram

Physics Faculty Publications and Presentations

Viscosities and diffusion rates of organics within secondary organic aerosol (SOA) remain uncertain. Using the bead-mobility technique, we measured viscosities as a function of water activity (a_w) of SOA generated by the ozonolysis of limonene followed by browning by exposure to NH₃ (referred to as brown limonene SOA or brown LSOA). These measurements together with viscosity measurements reported in the literature show that the viscosity of brown LSOA increases by 3–5 orders of magnitude as the aw decreases from 0.9 to approximately 0.05. In addition, we measured diffusion coefficients of intrinsic fluorescent organic molecules within brown …

The Bridge Newsletter Spring 2019, Missouri University Of Science And Technology

The Bridge Newsletter

-Building better aerogels
-Bridge repair needs
-Incoming ASCE President speaks

Pindan Soils In The La Grange Area, West Kimberley: Land Capability Assessment For Irrigated Agriculture, 2nd Edition, Henry Smolinski, Paul Galloway, Justin Laycock

Resource management technical reports

This report identifies areas of Pindan country along the Great Northern Highway, south of Broome from Roebuck to Mandora, which have high potential for irrigated agriculture. The area contains significant reserves of potable groundwater defined by the La Grange groundwater allocation area, which is based on the surficial Broome Sandstone aquifer.

Over the past 30 years, several small- to medium-scale irrigation developments have been successfully established in the region. The water opportunities project aims to identify and quantify the land and water resources of the region to ensure any future expansion of irrigated agriculture is sustainable and will not have …

Genetic Associations Of Hemoglobin In Children With Chronic Kidney Disease In The Pedigfr Consortium, Meredith A Atkinson, Rui Xiao, Anna Köttgen, Elke Wühl, Craig S Wong, Matthias Wuttke, Aysun K Bayazit, Salim Çalişkan, Bradley A Warady, Franz Schaefer, Susan L Furth

Pediatrics Research and Scholarship

BACKGROUND: Genome-wide association studies (GWAS) in healthy populations have identified variants associated with erythrocyte traits, but genetic causes of hemoglobin variation in children with CKD are incompletely understood.

METHODS: The Pediatric Investigation of Genetic Factors Linked with Renal Progression (PediGFR) Consortium comprises three pediatric CKD cohorts: Chronic Kidney Disease in Children (CKiD), Effect of Strict Blood Pressure Control and ACE Inhibition on the Progression of CRF in Pediatric Patients (ESCAPE), and Cardiovascular Comorbidity in Children with CKD (4C). We performed cross-sectional and longitudinal association studies of single-nucleotide polymorphisms (SNPs) in 1125 patients.

RESULTS: Children of European (n = 725) or …

Connecting Researchers To Data Repositories In The Earth, Space, And Environmental Sciences, Michael Witt, Shelley Stall, Ruth Duerr, Raymond Plante, Martin Fenner, Robin Dasler, Patricia Cruse, Sophie Hou, Robert Ulrich, Danie Kinkade

Libraries Faculty and Staff Scholarship and Research

The Repository Finder tool was developed to help researchers in the domain of Earth, space, and environmental sciences to identify appropriate repositories where they can deposit their research data and to promote practices that implement the FAIR Principles, encouraging progress toward sharing data that are findable, accessible, interoperable, and reusable. Requirements for the design of the tool were gathered through a series of workshops and working groups as a part of the Enabling FAIR Data initiative led by the American Geophysical Union that included the development of a decision tree that researchers may follow in selecting a data repository, interviews …

Climate Change And Occupational Health: Are There Limits To Our Ability To Adapt?, Marcus Dillender

Upjohn Institute Working Papers

This study considers the relationship between temperature and occupational health. The results indicate that both high and low temperatures increase injury rates and that high temperatures have more severe adverse effects in warmer climates, which suggests that avoiding the adverse effects of high temperatures may be easier for workers when hot days are rarer. While research on the effect of temperature on mortality finds substantial capacity for adaption with current technology, the results presented here suggest that outdoor workers face challenges in adapting to high temperatures.