Digital Commons Network^™

Psyx 330.01: Child Development, Rachel L. Severson

University of Montana Course Syllabi

No abstract provided.

Psyx 250n.02: Fundamentals Of Biological Psychology, Robert S. Hall

University of Montana Course Syllabi

No abstract provided.

Psyx 233.50: Fundamentals Of The Psychology Of Aging, Nora Grace Uhrich

University of Montana Course Syllabi

No abstract provided.

Psyx 120.50: Introduction To Psychological Research Methods I, Susan Greene

University of Montana Course Syllabi

No abstract provided.

Soci 260s.01: Introduction To Juvenile Delinquency, Jackson M. Bunch

University of Montana Course Syllabi

No abstract provided.

Extra-Mitochondrial Cu/Zn Superoxide Dismutase (Sod1) Is Dispensable For Protection Against Oxidative Stress But Mediates Peroxide Signaling In Saccharomyces Cerevisiae, Claudia Montllor-Albalate, Alyson E. Colin, Bindu Chandrasekharan, Naimah Bolaji, Joshua L. Andersen, Franklin W. Outten, Amit R. Reddi

Faculty Publications

Cu/Zn Superoxide Dismutase (Sod1) is a highly conserved and abundant metalloenzyme that catalyzes thedisproportionation of superoxide radicals into hydrogen peroxide and molecular oxygen. As a consequence, Sod1serves dual roles in oxidative stress protection and redox signaling by both scavenging cytotoxic superoxideradicals and producing hydrogen peroxide that can be used to oxidize and regulate the activity of downstreamtargets. However, the relative contributions of Sod1 to protection against oxidative stress and redox signaling arepoorly understood. Using the model unicellular eukaryote, Baker's yeast, we found that only a small fraction ofthe total Sod1 pool is required for protection against superoxide toxicity and that …

An In Vitro And In Vivo Evaluation Of The Anticancer Potential Of Resveratrol And Pterostilbene Against Hpv-E6 Positive Cancers, Kaushiki Chatterjee

Dissertations, Theses, and Capstone Projects

Cervical cancer remains as one of the most prevalent cancers effecting women globally. Lack of awareness and affordable prophylactic and therapeutic options in developing countries drive the need for alternative low-cost approaches. Dietary polyphenols have gained increased attention as possible anti-cancer agents. Our study aims to investigate whether two natural structural analogs, resveratrol and pterostilbene, exhibit anti-HPV (Human papillomavirus) activity in cervical cancer. To determine the efficacy of these polyphenols, extensive in vitro and in vivo analyses were carried out. For the in vitro studies we utilized human HeLa cells (HPV18 positive) and murine TC1 cells (HPV 16 oncogene positive). …

Co-Expression Of Vegf And Il-6 Family Cytokines Is Associated With Decreased Survival In Her2 Negative Breast Cancer Patients: Subtype-Specific Il-6 Family Cytokine-Mediated Vegf Secretion, Ken Tawara, Hannah Scott, Jacqueline Emathinger, Alex Ide, Ryan Fox, Daniel Greiner, Dollie Lajoie, Danielle Hedeen, Madhuri Nandakumar, Andrew J. Oler, Ryan Holzer, Cheryl Jorcyk

Biology Faculty Publications and Presentations

Breast cancer cell-response to inflammatory cytokines such as interleukin-6 (IL-6) and oncostatin M (OSM) may affect the course of clinical disease in a cancer subtype-dependent manner. Furthermore, vascular endothelial growth factor A (VEGF) secretion induced by IL-6 and OSM may also be subtype-dependent. Utilizing datasets from Oncomine, we show that poor survival of invasive ductal carcinoma (IDC) breast cancer patients is correlated with both high VEGF expression and high cytokine or cytokine receptor expression in tumors. Importantly, epidermal growth factor receptor-negative (HER2-), but not HER2-positive (HER2+), patient survival is significantly lower with high tumor co-expression of VEGF and OSM, OSMRβ, …

More Than A Pretty Interface: The Louisiana Digital Library As A Data Hub, Sl Ziegler

Faculty Publications

The Louisiana Digital Library (LDL) is an online platform for libraries, museums, archives, and historical organizations across the state. The books, manuscripts, oral histories, maps, and photographs held in the LDL showcase the cultural resources of Louisiana. The interface enables users to discover materials through search and browse, and to view and interact with these materials. The metadata about these items is also a great asset. When explored in their entirety, the data held in the LDL is as valuable as the digital facsimiles. The LDL may be conceptualized as a data hub, a place to gather and share the …

Rigor And Relationships: The Positive Case For Integration In Schools And Neighborhoods, Rachel D. Godsil

Cardozo Law Review

This Essay first explores the current conditions of schools and neighborhoods and the impediments to achieving successful integration in schools- implicit bias, racial anxiety, and stereotype threat. Second, the Essay then identifies the strategies that are being employed in some schools to overcome these impediments and create quality schools that educate all students in a just and effective manner. Finally, the Essay explains how integrated neighborhoods would be the most effective long-term solution to the stereotyping and biases that underlie racial injustices across the board.

Comparison Of Classical Method And Optimization Methods For Estimating Parameters In Nonlinear Ordinary Differential Equation, Emad Hazim Aboudi, Wafa Jaafar Hussein

Journal of Economics and Administrative Sciences

This study is concerned with the estimation of constant and time-varying parameters in non-linear ordinary differential equations, which do not have analytical solutions. The estimation is done in a multi-stage method where constant and time-varying parameters are estimated in a straight sequential way from several stages. In the first stage, the model of the differential equations is converted to a regression model that includes the state variables with their derivatives and then the estimation of the state variables and their derivatives in a penalized splines method and compensating the estimations in the regression model. In the second stage, the pseudo- …

Supportive Hand-Holding Attenuates Pupillary Responses To Stress In Adult Couples, Wendy C. Birmingham, Tyler C. Graff, Steven G. Luke

Faculty Publications

Background

Social relationships, particularly marriage, have been shown to ameliorate the potentially pathogenic impact of stressful events but prior research has been mostly aimed at downstream effects, with less research on real-time reactivity. Pupillometry is an innovative procedure that allows us to see the effects of acute stress in real time. The muscles that control pupil size are linked to the autonomic nervous system, so that when stressed, the pupils dilate; this occurs within 200ms. This quick response allows us to see the immediate effects of acute stress on the autonomic nervous system (ANS), and the real-time effects of social …

Four Structural Variants Associated With Human-Directed Sociability In Dogs Are Not Found In Tame Red Foxes (Vulpes Vulpes), Estelle R. Bastounes, Halie M. Rando, Jennifer L. Johnson, Lyudmila N. Trut, Benjamin N. Sacks, Carlos A. Driscoll, Bridgett Vonholdt, Anna V. Kukekova

Computer Science: Faculty Publications

No abstract provided.

Detection Of Hfe Haemochromatosis In The Clinic And Community Using Standard Erythrocyte Tests, Niwansa Adris, Simon Hazeldine, Peter Bentley, Debbie Trinder, Anita C.G. Chua, Lawrie W. Powell, Louise E. Ramm, Grant A. Ramm, John K. Olynyk

Research outputs 2014 to 2021

Detection of HFE Haemochromatosis (HH) is challenging in the absence of clinical features. HH subjects have elevated erythrocyte parameters compared to those without HH, but it remains unclear how this could be applied in clinical practice. Thus, we determined the sensitivity, specificity and clinical utility of erythrocyte parameters in 144 HH subjects with (n = 122) or without (n = 22) clinical and/or biochemical expression of iron overload, 1844 general population controls, and 700 chronic disease subjects. For both expressing and non-expressing HH subjects, the mean pre- and post-phlebotomy values of mean cell volume (MCV) and mean cell haemoglobin (MCH) …

Manifold-Valued Image Generation With Wasserstein Generative Adversarial Nets, Zhiwu Huang, Wu J., G. L. Van

Research Collection School Of Computing and Information Systems

Generative modeling over natural images is one of the most fundamental machine learning problems. However, few modern generative models, including Wasserstein Generative Adversarial Nets (WGANs), are studied on manifold-valued images that are frequently encountered in real-world applications. To fill the gap, this paper first formulates the problem of generating manifold-valued images and exploits three typical instances: hue-saturation-value (HSV) color image generation, chromaticity-brightness (CB) color image generation, and diffusion-tensor (DT) image generation. For the proposed generative modeling problem, we then introduce a theorem of optimal transport to derive a new Wasserstein distance of data distributions on complete manifolds, enabling us to …

Predator-Prey Dynamics Of Bald Eagles And Glaucous-Winged Gulls At Protection Island, Washington, Usa, Shandelle M. Henson, Robert A. Desharnais, Eric T. Funasaki, Joseph G. Galusha, James W. Watson, James L. Hayward

Faculty Publications

1. Bald eagle (Haliaeetus leucocephalus) populations in North America rebounded in the latter part of the twentieth century, the result of tightened protection and outlawing of pesticides such as DDT. An unintended consequence of recovery may be a negative impact on seabirds. During the 1980s, few bald eagles disturbed a large glaucous‐winged gull (Larus glaucescens) colony on Protection Island, Washington, USA, in the Salish Sea. Breeding gull numbers in this colony rose nearly 50% during the 1980s and early 1990s. Beginning in the 1990s, a dramatic increase in bald eagle activity ensued within the colony, after which began a significant …

Reckless Juveniles, Kimberly Thomas

Articles

Modern doctrine and scholarship largely take it for granted that offenders should be criminally punished for reckless acts.1 Yet, developments in our understanding of human behavior can shed light on how we define and attribute criminal liability, or at least force us to grapple with the categories that have existed for so long. This Article examines recklessness and related doctrines in light of the shifts in understanding of adolescent behavior and its biological roots, to see what insights we might attain, or what challenges these understandings pose to this foundational mens rea doctrine. Over the past decade, the U.S. Supreme …

The Effect Of Expressive Writing On The Math Anxiety Scores Of Middle School Students Enrolled In A Public School In East Texas, Angela D. Ruark

Doctoral Dissertations and Projects

Math anxiety is a serious concern for educators and students. Students who may otherwise be successful can find themselves incapacitated to think and perform to their abilities due to this issue. Math anxiety negatively affects academic performance and deters students from pursuing math-based careers. This is particularly true for female students. Effective interventions are needed to address these issues. Expressive writing is one such intervention that has shown promise in reducing math anxiety with older students. This study investigated the impact of expressive writing on the math anxiety levels of middle school students according to group and gender. An experimental, …

Mythology, Morality, And The Messiah: How Natural Moral Law And Hero Myth Entail That Jesus Christ Is The Best Possible Hero, Matthew J. Coombe

Doctoral Dissertations and Projects

Essentially this dissertation is an abductive argument for Jesus Christ being the best possible hero. The abductive argument is concerned with the synthesis of several different disciplines: natural theology, general revelation, ethics, natural law (meta-ethics), literary criticism, Biblical criticism, and mythology. When synthesized the most reasonable conclusion for the data is that Jesus Christ is the best possible hero. All of the disciplines work together: Natural theology establishes the axiological basis for moral realism and moral knowledge. General revelation acts as a universal imprinter, which not only imbeds man with moral knowledge, but also with inherent notions of heroism—heroism and …

Bioh 280.01: From Molecules To Mind - Fundamentals Of Neuroscience, Christopher M. Comer, Nathan Insel

University of Montana Course Syllabi

No abstract provided.

Psyx 270.50: Fundamental Psychology Of Learning, Bethany Grace Gorter

University of Montana Course Syllabi

No abstract provided.

Chmy 123.00: Introduction To Organic And Biochemistry, Brooke Martin

University of Montana Course Syllabi

No abstract provided.

Biob 272.00: Genetics And Evolution, Douglas J. Emlen

University of Montana Course Syllabi

No abstract provided.

Bioo 335.00: Rocky Mountain Flora, Lila Fishman

University of Montana Course Syllabi

No abstract provided.

Biom 594.01: Professional Seminar, Brent J. Ryckman

University of Montana Course Syllabi

No abstract provided.

Biom 250n.01: Microbiology For Health Sciences, James D. Driver

University of Montana Course Syllabi

No abstract provided.

Multi-Tissue Transcriptomes Of Caecilian Amphibians Highlight Incomplete Knowledge Of Vertebrate Gene Families, María Torres-Sánchez, Christopher J. Creevey, Etienne Kornobis, David J. Gower, Mark Wilkinson, Diego San Mauro

Neuroscience Faculty Publications

RNA sequencing (RNA-seq) has become one of the most powerful tools to unravel the genomic basis of biological adaptation and diversity. Although challenging, RNA-seq is particularly promising for research on non-model, secretive species that cannot be observed in nature easily and therefore remain comparatively understudied. Among such animals, the caecilians (order Gymnophiona) likely constitute the least known group of vertebrates, despite being an old and remarkably distinct lineage of amphibians. Here, we characterize multi-tissue transcriptomes for five species of caecilians that represent a broad level of diversity across the order. We identified vertebrate homologous elements of caecilian functional genes of …

Anty 101h.80: Anthropology And The Human Experience, David G. Kerr

University of Montana Course Syllabi

No abstract provided.

Anty 101h.02: Anthropology And The Human Experience, David G. Kerr

University of Montana Course Syllabi

No abstract provided.

Biob 101n.50: Discover Biology, Andrea T. Green

University of Montana Course Syllabi

No abstract provided.