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Alma Link Resolver Title & Issn Report (Top 500) 2018-2019, Andreé J. Rathemacher

Technical Services Reports and Statistics

Statistics for 2018-2019 on the total number of OpenURL requests by journal title and ISSN made to the Ex Libris Alma link resolver for items held by the University of Rhode Island Libraries. Includes only the top 500 journals.

Information provided includes journal Title, ISSN, EISSN, Number of Requests, Number of Clicked Requests, % Clicks from Requests.

Cohort Description Of The Madagascar Health And Environmental Research–Antongil (Mahery–Antongil) Study In Madagascar, Christopher D. Golden, Cortni Borgerson, Benjamin L. Rice, Lindsay H. Allen, Evelin Jean Gasta Anjaranirina, Christopher B. Barrett, Godfred Boateng, Jessica A. Gephart, Daniela Hampel, Daniel L. Hartl, Erwin Knippenberg, Samuel S. Myers, Dera H. Ralalason, Herlyne Ramihantaniarivo, Hervet Randriamady, Setareh Shahab-Ferdows, Bapu Vaitla, Sarah K. Volkman, Miadana Arisoa Vonona

Department of Anthropology Faculty Scholarship and Creative Works

The Madagascar Health and Environmental Research-Antongil (MAHERY-Antongil) study cohort was set up in September 2015 to assess the nutritional value of seafood for the coastal Malagasy population living along Antongil Bay in northeastern Madagascar. Over 28 months of surveillance, we aimed to understand the relationships among different marine resource governance models, local people’s fish catch, the consumption of seafood, and nutritional status. In the Antongil Bay, fisheries governance takes three general forms: traditional management, marine national parks, and co-management. Traditional management involves little to no involvement by the national government or non-governmental organizations, and focuses on culturally accepted Malagasy community …

“I Don’T Want To Look Sick Skinny”: Perceptions Of Body Image And Weight Loss In Hispanics Living With Hiv In South Texas, Jordan W. Abel, Omar Allen, Delia Bullock, Erin Finley, Elizabeth Walter, Phillip Schnarrs, Barbara S. Taylor

Journal of Health Disparities Research and Practice

Objective: Obesity is rising in people with HIV (PLWH) and Hispanics. Both HIV and obesity are associated with cardiovascular disease morbidity and mortality. Our goal is to understand perceptions of body image and lifestyle in Hispanics with HIV to adapt interventions appropriately.

Methods: We conducted semi-structured interviews with 22 Hispanic PLWH and 6 providers. Purposive sampling selected patient participants across weights and genders. Interviews were coded and analyzed using grounded theory, comparing perspectives between patients with and without obesity, and patients and providers.

Results: Participants felt obesity and diabetes were “normal” in the community. Patients exhibited understanding of healthy diet …

“You Come Back To The Same Ole Shit:” A Qualitative Study Of Smoking Cessation Barriers Among Women Living With Hiv: Implications For Intervention Development, Faith E. Fletcher, Damon J. Vidrine, Meredith K. Buchberg Trejo, Yamile' Molina, Beverly E. Sha, Brenikki R. Floyd, Noreen Sarhene, Jamesetta Mator, Alicia K. Matthews

Journal of Health Disparities Research and Practice

Although tobacco use among women living with HIV (WLWH) is decreasing, the prevalence is more than double that of women in the general population and remains an important health behavior to target among WLWH. Few smoking cessation interventions specifically focus on the unique social and medical needs of women living with HIV (WLWH). Thus, the investigative team engaged WLWH (N=18) in qualitative focus groups to: 1) understand barriers and facilitators to smoking cessation; and 2) inform intervention structure and content priorities. Participants identified salient reasons for smoking and barriers to smoking cessation, which included coping mechanisms for life stressors, HIV-related …

Low Frequency Of Regulatory B-Cells And Increased Cd4+ And Cd8+ Interferon-Γ-Producing Cells In Patients With Tropical Spastic Paraparesis Associated With Human T-Cell Lymphotropic Virus Type, Yulieth Cristina Bermúdez Burbano, Angie Vanessa Caicedo Paz, Cristhian Camilo Rivera Caldon, Juan Sebastián Rodríguez Constain, Gloria Inés Ávila Gonzáles, Julio César Klínger Hernández, Nancy Marin-Agudelo, Rosa Amalia Dueñas-Cuellar, Victoria Eugenia Niño Castaño

Open Access Publications

INTRODUCTION: Tropical spastic paraparesis/HTLV-1 associated myelopathy (TSP/HAM) is a disease caused by human T-cell lymphotropic virus type 1 (HTLV-I) that mainly infects CD4 T cells-for example, those of the CD4+CD25hiFOXP3+ [Treg] phenotype-where it inhibits forkhead box protein P3 (FOXP3) expression and promotes interferon-γ (IFN-γ) expression. However, the role it exerts on regulatory B cells (CD19+CD24hiCD38hi; Breg) is unknown.

METHODS: The frequencies of Treg and Breg cells was evaluated and the Th1 profiles were assessed in TSP/HAM patients and healthy control subjects.

RESULTS: Low percentages of Breg cells and high production of IFN-γ were observed in patients compared to those in …

Low Frequency Of Regulatory B-Cells And Increased Cd4+ And Cd8+ Interferon-Γ-Producing Cells In Patients With Tropical Spastic Paraparesis Associated With Human T-Cell Lymphotropic Virus Type, Yulieth Cristina Bermúdez Burbano, Angie Vanessa Caicedo Paz, Cristhian Camilo Rivera Caldon, Juan Sebastián Rodríguez Constain, Gloria Inés Ávila Gonzáles, Julio César Klínger Hernández, Nancy Marin-Agudelo, Rosa Amalia Dueñas-Cuellar, Victoria Eugenia Niño Castaño

Open Access Publications

INTRODUCTION: Tropical spastic paraparesis/HTLV-1 associated myelopathy (TSP/HAM) is a disease caused by human T-cell lymphotropic virus type 1 (HTLV-I) that mainly infects CD4 T cells-for example, those of the CD4+CD25hiFOXP3+ [Treg] phenotype-where it inhibits forkhead box protein P3 (FOXP3) expression and promotes interferon-γ (IFN-γ) expression. However, the role it exerts on regulatory B cells (CD19+CD24hiCD38hi; Breg) is unknown.

METHODS: The frequencies of Treg and Breg cells was evaluated and the Th1 profiles were assessed in TSP/HAM patients and healthy control subjects.

RESULTS: Low percentages of Breg cells and high production of IFN-γ were observed in patients compared to those in …

Unsettling Indian Health Services: Secularism, Modern Medicine, & The Reproduction Of The U.S. Settler State Through The 1954 Transfer Act, Jillian Elizabeth Grisel

American Studies ETDs

This thesis takes up the role of secularism in modern medicine as a political doctrine that works in service of settler colonialism. I argue the Declaration of Human Rights and the World Health Organization (WHO) globally institutionalized secular ideologies in the post-World War II environment. This thesis links how this global reordering came to inform U.S. health policy by examining how government officials and medical experts drew from the WHO and framed infectious diseases as a security issue to impose a biomedical order in Indian country. By contextualizing modern medicine within a settler political economy and secular political doctrine, I …

Gut Microbiome: Profound Implications For Diet And Disease, Ronald D. Hills Jr., Benjamin A. Pontefract, Hillary R. Mishcon, Cody A. Black, Steven C. Sutton, Cory R. Theberge

Pharmaceutical Sciences Faculty Publications

The gut microbiome plays an important role in human health and influences the development of chronic diseases ranging from metabolic disease to gastrointestinal disorders and colorectal cancer. Of increasing prevalence in Western societies, these conditions carry a high burden of care. Dietary patterns and environmental factors have a profound effect on shaping gut microbiota in real time. Diverse populations of intestinal bacteria mediate their beneficial effects through the fermentation of dietary fiber to produce short-chain fatty acids, endogenous signals with important roles in lipid homeostasis and reducing inflammation. Recent progress shows that an individual’s starting microbial profile is a key …

Antibacterial S-Heterosubstituted Disulfides, Edward Turos, Praveen Ramaraju

USF Patents

Synthetically-derived S,S-heterodisubstituted disulfides that exhibit potent in vitro antibacterial activity against a variety of bacteria, including Staphylococcus aureus, methicillin-resistant Staphylococcus aureus and Francisella tularensis. The present invention provides compounds, methods and compositions effective to treat microbial/bacterial infections, and, especially, infections arising from bacteria which have developed resistance to conventional antibiotics.

Bitter Taste Receptors For Asthma Therapeutics., Ajay P. Nayak, Sushrut D. Shah, James V. Michael, Deepak A. Deshpande

Center for Translational Medicine Faculty Papers

Clinical management of asthma and chronic obstructive pulmonary disease (COPD) has primarily relied on the use of beta 2 adrenergic receptor agonists (bronchodilators) and corticosteroids, and more recently, monoclonal antibody therapies (biologics) targeting specific cytokines and their functions. Although these approaches provide relief from exacerbations, questions remain on their long-term efficacy and safety. Furthermore, current therapeutics do not address progressive airway remodeling (AR), a key pathological feature of severe obstructive lung disease. Strikingly, agonists of the bitter taste receptors (TAS2Rs) deliver robust bronchodilation, curtail allergen-induced inflammatory responses in the airways and regulate airway smooth muscle (ASM) cell proliferation and mitigate …

Assessment Of Post-Discharge Health Care Utilization In Infants With Neonatal Opioid Withdrawal Syndrome, Shikhar Shrestha

Pharmaceutical Sciences ETDs

Background/Objectives: Children born to mothers with opioid use disorder often show withdrawal effects characterized by increased stress, hyperirritability, tremors, tachycardia, sleep deprivation, and gastrointestinal discomfort, commonly known as “neonatal opioid withdrawal syndrome” (NOWS). Studies have shown that the effect of NOWS can lead to several health-related disorders later in life leading to increased health care utilization. However, detailed study of post-discharge health care utilization, specifically focusing on encounters with the health care system is currently lacking in the literature. Our objective was to evaluate health care utilization in infants who were diagnosed with NOWS during a one-year follow-up period after …

Role Of Host Cell Β-Catenin During Toxoplasma Gondii Infection, Cameron H. Ranken

Biology ETDs

The microbial pathogen Toxoplasma gondii is an intracellular protozoan that actively invades host cells and simultaneously creates a specialized parasitophorous vacuole within which the parasite lives and replicates. The parasite molecular machinery that drives establishment of the intracellular niche is relatively well known. However, it is now emerging that Toxoplasma exploits less well-understood host cell components to enable successful infection. Here, we examined the role of host Wnt/β-catenin during T. gondii infection. Using human fibroblasts and a mouse dendritic cell line, we found that infection with Toxoplasma stimulated both upregulation and nuclear localization of β-catenin. Using a transwell experimental approach, …

Indirect Effects In A Planktonic Disease System, Zoi Rapti, Tara E. Stewart Merrill, Liam E. Mueller-Brennan, Jerry H. Kavouras, Carla E. Cáceres

Biology Department Faculty Articles

Indirect effects, both density- and trait-mediated, have been known to act in tandem with direct effects in the interactions of numerous species. They have been shown to affect populations embedded in competitive and mutualistic networks alike. In this work, we introduce a four-dimensional system of ordinary differential equations and investigate the interplay between direct density-effects and density- and trait-mediated indirect effects that take place in a yeast parasite–zooplankton host–incompetent competitor system embedded in a food web which also includes resources and predators. Among our main findings is the demonstration that indirect effects cause qualitative and quantitative changes almost indistinguishable from …

Celac: Mexican Foreign Policy Interest On Latin American And Caribbean Regionalism, Demeiati Nur Kusumaningrum

Global: Jurnal Politik Internasional

La Comunidad de Estados Latinoamericanos y Caribeños (CELAC) was initiated in 2011 as a forum for dialogue and consensus between Latin American and Caribbean governments where it forms a trading block that excludes the United States and Canada. The US objected to the establishment of CELAC which seemed to challenges the former regional organization (OAS). This paper aims to analyze the considerations of the Mexican government to join CELAC in the midst of mutual agreement with US and NAFTA. Theory of formulation of foreign policy is used to answer the sources of political consideration of the Mexican government. It is …

Medical School Watercooler Newsletter - July 14, 2019, Lindsey Lyle

Watercooler Newsletter

This is the July 14, 2019 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

USA Internal Medicine Residency Program turns community service project into annual donation drive

August Med School Café: "What Is Urogynecology?"

Mark Your Calendar: Cardiology grand rounds July 26

Medical students work closely with faculty for unique learning experiences

Medical student hangs up her gloves for scrubs

Conference Program, Christina Chan, Mattheos Koffas, Steffen Schaffer, Rashmi Kshirsagar

Biochemical and Molecular Engineering XXI

No abstract provided.

Facial Fluctuating Asymmetry: Developmental Origins And Implications For Long-Term Health, Katelyn Marie Rusk Phd

Anthropology ETDs

Fluctuating asymmetry (FA), characterized by random left-right deviations from perfect symmetry in anatomical structures, is a form of bilateral asymmetry that is thought to reflect underlying developmental instability (DI). DI refers to an organism’s relative ability to buffer against stochastic fluctuations in environmental conditions throughout development. FA is commonly used within evolutionary biology and anthropology as a cumulative indicator of chronic stress exposure during development and its consequences for long-term health. While the FA literature is extensive, there are two primary areas of inquiry that remain incomplete: assessing the full breadth of health correlates of FA across the human life …

Computational Investigation Of The Interactions Between Bioactive Compounds And Biological Assemblies, Tye D. Martin

Biomedical Engineering ETDs

Small, biologically active molecules with unique properties and applications are potential solutions to a wide range of threats to global health including infectious agents and neurodegenerative disease. Experimental studies on a class of oligomeric p-phenylene ethynylenes (OPEs) have shown potential both as bioactive antimicrobials and fluorescent sensing agents for tracking amyloid-β (Aβ) aggregates found in Alzheimer’s Disease (AD). A second type of small molecule with potential applications in AD therapy, curcumin, has been found to interfere with Aβ fibril growth. Curcumin also attenuates Aβ-membrane interactions and Aβ toxicity. Our goal has been to use computational techniques to better understand the …

Biocide Resistance And Transmission Of Clostridium Difficile Spores Spiked Onto Clinical Surfaces From An American Health Care Facility, Calie Dyer, Lee P. Hutt, Robert Burky, Lovleen Tina Joshi

School of Biomedical Sciences

Clostridium difficile is the primary cause of antibiotic-associated diarrhea globally. In unfavourable environments the organism produces highly resistant spores which can survive microbicidal insult. Our previous research determined the ability of C. difficile spores to adhere to clinical surfaces; finding that spores had marked different hydrophobic properties and adherence ability. Investigation into the effect of the microbicide sodium dichloroisocyanurate on C. difficile spore transmission revealed that sub-lethal concentrations increased spore adherence without reducing viability. The present study examined the ability of spores to transmit across clinical surfaces and their response to an in-use disinfection concentration of 1,000-ppm of chlorine-releasing agent …

Mechanisms And Health Impact Of Insomnia As An Hiv Comorbidity, Brooke Genkin Rogers

Open Access Dissertations

Insomnia is a highly prevalent and interfering comorbidity to HIV infection, yet relatively understudied compared to other mental and behavioral health comorbidities. Nearly 80% of people living with HIV/AIDS (PLWHA) experience significant sleep difficulties characteristic of insomnia. This represents nearly 1 million of Americans with HIV/AIDS. Efforts have been made to identify factors that contribute to the development and maintenance of insomnia in PLWHA. However, no one pathway has been identified that could explain the overabundance of sleep problems in this population. Most limiting is that extant studies have studied sleep problems, but not clinical insomnia; and, often, those data …

Transmissible Dermatological Diseases Affecting Syrian Refugees In Lebanon, Nisrine Kawa, Edith Hanna, Abdul Rahman Bizri

Journal of Refugee & Global Health

The Syrian war led many to seek shelter in Lebanon, creating a major refugee crisis. Displaced populations in crowded unequipped settlements are vulnerable to infectious diseases. The burden and incidence of various transmissible skin conditions affecting Syrian refugees in Lebanon and their impact on the Lebanese public health system were evaluated. Literature regarding these conditions among Syrian refugees in host countries, and epidemiological data from the Lebanese Ministry of Public Health Surveillance Unit and primary health-care network were reviewed. Lebanon has witnessed skin disorder outbreaks associated with the Refugee crisis, mainly leishmaniasis, scabies and lice infestations with little data about …

A Quality Initiative To Reduce Pneumonia Readmissions And Mortality In Older Adults, Terri Morris

Dissertations

The United States (U.S.) healthcare system journey for making improvements in the quality and value of healthcare continues. Hospital organizations are required to compose and make publically available their health quality outcome data. The publication transparency and increased availability of local, regional and national health quality metrics, including readmission and mortality rates, to governmental agencies, health plans, investors, other hospitals, providers and potential patient and families’ knowledge, creates a competitive pressure for a hospital to assure their quality outcomes data are the best. Despite breakthrough improvements using innovative care models that target vulnerable and potentially high cost of care areas …

A Vaccine Administration Training Program To Increase Adolescent Vaccination Rates, Claire Jensen

Dissertations

Abstract

Immunizations have been proven to control life-threatening diseases. Often Registered Nurses (RNs) administer vaccines but are unsure how to discuss vaccines with vaccine hesitant patients. Missouri’s adolescent vaccination rates are below its neighboring states. This initiative’s purpose was to increase adolescent vaccine administrations at a Missouri County Health Department (MCHD).

This quality improvement initiative had an observational, cross-sectional, descriptive design. RNs employed at three MCHD clinics attended an adolescent vaccine administration training program (VAT) and completed pre-/post-tests regarding the Advisory Council on Immunization Practices recommendations. Medical record reviews from March 1-April 30, 2018 and March 1-April 30, 2019 compared …

Reducing Cautis In A Neurological Icu, Claire Mckee

Dissertations

Catheter-associated urinary tract infections (CAUTIs) are the primary source of infection in patients with urinary catheters and are the fourth leading cause of healthcare-associated infection. Because indwelling urinary catheters are not completely avoidable in hospitalized patients, it is crucial to utilize evidence-based research to prevent CAUTIs. A urinary catheter maintenance bundle is one way to reduce CAUTI rates in hospitalized patients. This quality improvement project utilizes a catheter maintenance bundle with seven elements with the aim of reducing CAUTI rates. The project takes place in a 20-bed neurological intensive care unit (ICU) in a larger tertiary care medical center. Prior …

A Behavioral Weight Loss Program For Low-Income Adults With Obesity And Hiv, Sophai Thach

Dissertations

Problem: Obesity, having a body mass index (BMI) of 30 kg/m² or greater, increases the risk for cardiovascular disease. For people living with HIV (PLWH), this increases their risk for myocardial infarctions by 50% and causes this life-threatening event to occur at a younger age compared to those who are not diagnosed with HIV.

Methods: With obesity disproportionately affecting people with low income, this study aims to evaluate the effects of a 12-week behavioral weight loss program that utilizes journaling as a self-monitoring tool, weekly educational classes, and individualized goal-setting on PLWH with obesity who live in …

A Collaboration For Clean Water In Guatemala, Linda S. Johanson

International Nursing Research Congress (INRC)

This collaboration between a medical mission team and a community service organization in the country of Guatemala addressed a United Nations developmental goal concerning safe drinking water. After the installation of clean water filters in two rural Guatemalan villages the percentage of infections was found to have decreased.

Mind The Gap: Improving Care Delivery And Patient Outcomes, Anna Dermenchyan, Therese Offer

International Nursing Research Congress (INRC)

Health care delivery requires an illustration of high quality and low cost. Addressing quality care gaps has historically relied on physicians with highly variable processes and inconsistent results. A standard system in the EHR can be used by all members of the healthcare team to track and improve care delivery.

Increasing Client Engagement In People Who Inject Drugs: Implementing Best-Practice For Syringe Service Programs, Tasha Turner-Bicknell

International Nursing Research Congress (INRC)

In light of the growing opioid epidemic and increased incidence and prevalence of HIV and Hepatitis C, national public health efforts engaging high-risk populations are crucial. People who inject drugs (PWID) are often disenfranchised from the healthcare system. Public health efforts to impact this population should focus on increasing engagement.

Neonatal Intensive Care Unit To Home Transition For Families Of Preterm Infants, Rita H. Pickler, Neera Goyal, Heather Tubbs Cooley, Margo Moore, Stephanie Sealschott, Karin Tepe

International Nursing Research Congress (INRC)

Preterm birth and subsequent hospitalization is a significant worldwide health concern with financial and human costs. The results of this study provide evidence for transition to home programs from both parent and care provider prospective.

Barriers To Treating And Managing Obesity, Anna Dermenchyan

International Nursing Research Congress (INRC)

Obesity rates are on the rise in the United States and worldwide. Primary care providers are key to treating and managing patients who are obese. This presentation highlights some of the barriers faced by primary care providers in treating and managing obesity.