Digital Commons Network^™

Physical Function And Fatigue In Older Hiv Adults In San Francisco, Usa, Soson Jong

International Nursing Research Congress (INRC)

Older HIV patients experience a variety of symptom including fatigue and lack of energy. A study conducted among older HIV patients in San Francisco, USA found that increasing physical activity (using Fitbit device) helps to improve fatigue and low energy symptoms.

Shots Fired: Significant Differences In Vaccine Knowledge Found Between Information Sources, Clinicians, And Laypeople, Benjamin James Wood, Tesla B. Sherrill, Jacob Wheat, Alexis Lynn Dietz, Sydney Elizabeth Carden, Rebecca Grace King, Kate Rocklein Kemplin

International Nursing Research Congress (INRC)

Globally, there are misconceptions about vaccinations and perceived implications. This research is a catalyst that empowers healthcare professionals to identify disparities in laypeoples' insight towards vaccinations which will prevent life-threatening childhood illness. Providing appropriate education is vital, as misinformation about vaccinations can threaten the health of entire societies.

Improving Proton Pump Inhibitor Prescription Practices As A Means To Decreasing Nosocomial Infections, Jens Langsjoen

Biomedical Sciences ETDs

Proton pump inhibitors (PPIs) are commonly prescribed to treat stomach acid related illnesses, but increase the risk of hospital acquired infections. Measuring hospital PPI overuse trends and provider willingness to adopt PPI reduction interventions can inform the feasibility of reducing PPI overuse. We: (1) interviewed physicians, pharmacists and IT leaders to determine options for hospital PPI reduction, (2) analyzed electronic health record data to determine patterns of PPI overuse, and (3) surveyed providers regarding their willingness to adopt PPI reduction interventions. PPI use was inappropriate in 32% of inpatient encounters locally and 38% nationally. ICU exposure increased the odds of …

Intervention Design Elements Are Associated With Frontline Health Workers' Performance To Deliver Infant And Young Child Nutrition Services In Bangladesh And Vietnam, Phuong Hong Nguyen, Sunny S. Kim, Lan Mai Tran, Purnima Menon, Edward A. Frongillo

Faculty Publications

Background: Frontline health workers (FLWs) are needed for delivering interventions at scale to reduce maternal and child undernutrition, but low- and middle-income countries often face inadequate FLW performance.

Objectives: We examined whether and how intervention design elements such as training, supervision, and mass media improved FLW performance in delivering nutrition services.

Methods: Survey data were collected in 2010 and 2014 as part of impact evaluations of Alive & Thrive (A&T) interventions to improve infant and young child feeding (IYCF) practices in Bangladesh and Vietnam. FLWs in A&T intensive (A&T-I) areas received specialized IYCF training, job aids, and regular supportive supervision. …

In Vivo Effectiveness And Safety Of Probiotics On Prophylaxis And Treatment Of Oral Candidiasis: A Systematic Review And Meta-Analysis, Lijun Hu, Mimi Zhou, Andrew L. Young, Weiwei Zhao, Zhimin Yan

All Dugoni School of Dentistry Faculty Articles

BACKGROUND: To systematically review and assess the in vivo effectiveness and safety of probiotics for prophylaxis and treating oral candidiasis.

METHODS: A literature search for studies published in English until August 1, 2018 was conducted in the following databases: PubMed, EMBASE, Cochrane Library, and Web of Science. Randomized controlled clinical trials and experimental mouse animal model studies comparing probiotics (at any dosage and in any form) with control groups (placebo, blank control or other agents) and reporting outcomes of the prophylactic and therapeutic effects were considered for inclusion. A descriptive study and, potentially, a meta-analysis were planned.

RESULTS: Six randomized …

Knowledge Of Hiv/Aids And Attitudes Toward Condom Use Among African American Men 18 To 35, Doris Ezomo, Catherine Jirak Monetti, Beverley E. Blair Brown

International Nursing Research Congress (INRC)

Study shows that minority youth challenge dominant norms and do not behave according to the these norms thereby risking their health. This study sought to determine whether attitudes towards condom use differs according to knowledge of HIV/AIDS, and demographics like age, education, income, length of relationships, and years sexually active.

Outcome Of Inadvertent High Dose Bcg Administration In Newborns At A Tertiary Care Hospital, Karachi- Case Series, Sonia Qureshi, Khalil Ahmad, Paras Fatima, Rabia M. Hassan, Farheen Sherali, Naureen Lalani, Fyezah Jehan, Syed Asad Ali, Farah Qamar

Department of Paediatrics and Child Health

Bacillus Calmette-Guérin (BCG) vaccine is given to newborns soon after birth. BCG vaccine overdose has been rarely reported. Here we report the outcome of newborns who accidently received high dose BCG at a tertiary care hospital, Karachi. We reviewed records of 26 newborns, who accidentally received intradermal high dose BCG, used for the treatment of urinary bladder cancers and 80 times higher dose than the BCG used for routine vaccination. The incident happened from 14-16th April, 2016 at Aga Khan University Hospital, Karachi. Analysis was carried out using SPSS. A total of 23/26(88.5%) newborns were followed for atleast 3 months …

Lee Named Uab Medicine Healthcare Epidemiologist, Alicia Rohan

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No abstract provided.

Building Global Citizens Through Paired International Student Community Health Experiences: A Us/Norwegian Initiative, Dianne Morrison-Beedy, Unni Jenssen

International Nursing Research Congress (INRC)

Paired international student community health experiences can be used to catalyze global collaborations. We discuss US-Norwegian evidence-based teaching approaches integrated into international student clinical experiences that address the sustainable development goals. We develop global citizens by capitalizing on a cultural experience addressing disenfranchised populations including the homeless and refugee/immigrant groups.

From Vaccine Vector To Oncomodulation: Understanding The Complex Interplay Between Cmv And Cancer., Nicole A. Wilski, Christopher M. Snyder

Department of Microbiology and Immunology Faculty Papers

Cytomegalovirus (CMV) is a herpesvirus that establishes a persistent, but generally asymptomatic, infection in most people in the world. However, CMV drives and sustains extremely large numbers of antigen-specific T cells and is, therefore, emerging as an exciting platform for vaccines against infectious diseases and cancer. Indeed, pre-clinical data strongly suggest that CMV-based vaccines can sustain protective CD8+ T cell and antibody responses. In the context of vaccines for infectious diseases, substantial pre-clinical studies have elucidated the effcacy and protective mechanisms of CMV-based vaccines, including in non-human primate models of various infections. In the context of cancer vaccines, however, much …

Efforts Targeting Factors Of Health Disparities That Impair Hiv Treatment Engagement, Graham F. Watts Sr, Heather Vaughan

Florida Public Health Review

Health disparities exist in Northeast Florida. Some locations experience morbidities at higher rates than others. Health zone 1 is a prime example. Differences in disease rates are interlaced with the social determinants of health, (SDOH). Long-standing social and structural influences of disparities are beyond the scope of Ryan White programs. However, empowerment for health promotion is a strategy for targeting health disparities. The Theory of Health Empowerment targets sense of agency and offers some leverage for helping people living with HIV/AIDS, (PLWHA) despite environments blemished by SDOH. Eclectic leadership occurring in a climate of respectful point-counter point discussions established the …

Lessons From The Field: A Systems Thinking Approach For Case Management Documentation, Graham F. Watts Sr, Angela E. Prince, Heather Vaughan, Porschia Mccray Watts, Beth Parker

Florida Public Health Review

Case management is a core HIV health service that focuses on service coordination—the seamless access to an array of integrated services. Integration aims to reduce barriers to medical care. In the busy HIV health services environment, inadequate documentation of case management activities limits the capacity of stakeholders to know what happens during care encounters. This study used theory and qualitative inquiry to uncover best practices that support optimal case management documentation. Two research questions guided the inquiry: What principles should arise in higher order cognitive functioning among case managers during client encounters? What characteristics of a system level approach to …

Pathogens Without Borders: Ecological Determinants Of Sexual Risk-Taking Behaviors Among International Travelers Across The Life Course, Yok-Fong Paat, Luis R. Torres-Hostos

School of Social Work Faculty Publications

Purpose

Drawing insights from the ecological theory, the purpose of this paper is to explore social determinants related to pathways to high-risk sexual behaviors of international travelers across their life span.

Design/methodology/approach

Data were collected from 45 international travelers in Houston, a critical transit point frequented by international visitors.

Findings

Overall, several ecological settings (individuals, interpersonal, institutional and contextual) related to two typologies of international travelers (risk takers vs non-risk takers) and their inclination to engage in high-risk sexual practices in an international or/and local context were identified.

Research limitations/implications

This research calls for the need to assess high-risk sexual …

Environmental Foundations Of Typhoid Fever In The Fijian Residential Setting, Aaron P. Jenkins, Stacy D. Jupiter, Adam Jenney, Alanieta Naucukidi, Namrata Prasad, Gandercillar Vosaki, Kim Mulholland, Richard Strugnell, Mike Kama, John A. Crump, Pierre Horwitz

Research outputs 2014 to 2021

Proximal characteristics and conditions in the residential setting deserve greater attention for their potential to influence typhoid transmission. Using a case-control design in Central Division, Republic of Fiji, we examined bacterial (coliform and Escherichia coli) contamination and chemical composition of water and soil as potential vehicles of exposure to Salmonella Typhi, combining observational analysis of residential living conditions, geospatial analysis of household locations, and factor analysis to explore multivariate associations with the risk of developing typhoid fever. Factors positively associated with typhoid infection related to drainage [phosphate (OR 4.235, p = 0.042) and E. coli concentrations (OR 2.248, p = …

Editorial Board

Karbala International Journal of Modern Science

No abstract provided.

Antibiotic Resistance And Molecular Characterization Of Bacteremia Escherichia Coli Isolates From Newborns In The United States., Bryan K. Cole, Marko Ilikj, Cindy B. Mccloskey, Susana Chavez-Bueno

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Escherichia coli is a major cause of neonatal sepsis. Contemporary antibiotic resistance data and molecular characterization of neonatal E. coli bacteremia isolates in the US are limited.

METHODS: E. coli blood isolates, antibiotic susceptibility data, and clinical characteristics were obtained from prospectively identified newborns from 2006 to 2016. The E. coli isolates were classified using an updated phylogrouping method and multi-locus sequence typing. The presence of several virulence traits was also determined.

RESULTS: Forty-three newborns with E. coli bacteremia were identified. Mean gestational age was 32.3 (SD±5.4) weeks. Median age was 7 days (interquartile range 0-10). Mortality (28%) occurred …

Sickle Cell Disease Complications: Prevalence And Resource Utilization, Nirmish Shah, Menaka Bhor, Lin Xi, Jincy Paulose, Huseyin Yuce

Publications and Research

Objectives: This study evaluated the prevalence rate of vaso-occlusive crisis (VOC) episodes, rates of uncomplicated and complicated VOC episodes, and the primary reasons for emergency room (ER) visits and inpatient admissions for sickle cell disease (SCD) patients.

Methods: The Medicaid Analytic extracts database was used to identify adult SCD patients using claims from 01JUL2009-31DEC2012. The date of the first observed SCD claim was designated as the index date. Patients were required to have continuous medical and pharmacy benefits for .6 months baseline and .12 months follow-up period. Patient demographics, baseline clinical characteristics, the rate of uncomplicated and complicated VOC (VOC …

Multiscale Model Of Regional Population Decline In Little Brown Bats Due To White‐Nose Syndrome, Andrew M. Kramer, Claire S. Teitelbaum, Ashton Griffin

KIP Articles

The introduced fungal pathogen Pseudogymnoascus destructans is causing decline of several species of bats in North America, with some even at risk of extinction or extirpation. The severity of the epidemic of white‐nose syndrome caused by P. destructans has prompted investigation of the transmission and virulence of infection at multiple scales, but linking these scales is necessary to quantify the mechanisms of transmission and assess population‐scale declines. We built a model connecting within‐hibernaculum disease dynamics of little brown bats to regional‐scale dispersal, reproduction, and disease spread, including multiple plausible mechanisms of transmission. We parameterized the model using the approach of …

Key Inflammatory Pathway Activations In The Mci Stage Of Alzheimer’S Disease, Jagan A. Pillai, Sean Maxwell, Lynn M. Bekris, Stephen M. Rao, Mark R. Chance, James B. Leverenz

Faculty Scholarship

Objective: To determine the key inflammatory pathways that are activated in the peripheral and CNS compartments at the mild cognitive impairment (MCI) stage of Alzheimer’s disease (AD). Methods: A cross-sectional study of patients with clinical and biomarker characteristics consistent with MCI-AD in a discovery cohort, with replication in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort. Inflammatory analytes were measured in the CSF and plasma with the same validated multiplex analyte platform in both cohorts and correlated with AD biomarkers (CSF Aβ42, total tau (t-tau), phosphorylated tau (p-tau) to identify key inflammatory pathway activations. The pathways were additionally validated by evaluating …

Design And Synthesis Of Novel Agents For The Treatment Of Tropical Diseases, Linda Corrinne Barbeto

USF Tampa Graduate Theses and Dissertations

Infectious diseases have had an impact on populations since the beginning of humanity. Despite huge advances in the fight against these conditions, they continue to be the leading cause of death and disability for a large portion of the world’s populace. Those most adversely affected predominately live in the more improvised areas of the developing world. Often treatments are made inaccessible to these areas due to cost, complicated administration requirements, severe side effects, and / or compound instability. Even when treatments are available the accelerated development of resistance has created an urgent need for the creation of new molecules with …

Research News. Publications, 2019. Volume 2, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period April 1 through June 30, 2019

Entomology In The 21st Century: Tackling Insect Invasions, Promoting Advancements In Technology, And Using Effective Science Communication - 2018 Student Debates, Casey Parker, Lina Bernaola, Benjamin W. Lee, Dane Elmquist, Abigail Cohen, Adrian Marshall, James Hepler, Adrian Pekarcik, Emily Justus, Kendall King, Tae Young Lee, Carlos Esquivel, Kayleigh Hauri, Christopher Mccullough, Whitney Hadden, Max Ragozzino, Morgan Roth, James Villegas, Emily Kraus, Michael Becker, Megan Mulcahy, Rui Chen, Priyanka Mittapelly, C. Scott Clem, Rachel Skinner, Tanya Josek, Daniel Pearlstein, Jonathan Tetlie, Anh Tran, Anthony Auletta, Edwin Benkert, Dylan Tussey

Faculty Publications

The 2018 student debates of the Entomological Society of America were held at the Joint Annual Meeting for the Entomological Societies of America, Canada, and British Columbia in Vancouver, BC. Three unbiased introductory speakers and six debate teams discussed and debated topics under the theme aEntomology in the 21st Century: Tackling Insect Invasions, Promoting Advancements in Technology, and Using Effective Science Communication'. This year's debate topics included: 1) What is the most harmful invasive insect species in the world? 2) How can scientists diffuse the stigma or scare factor surrounding issues that become controversial such as genetically modified organisms, agricultural …

Short Relative Leg Length Is Associated With Overweight And Obesity In Mexican Immigrant Women, Mireya Vilar-Compte, James Macinko, Beth C. Weitzman, Carlos M. Avendaño-Villela

Department of Public Health Scholarship and Creative Works

Background: Prior research suggests that undernutrition and enteric infections predispose children to stunted growth. Undernutrition and infections have been associated with limited access to healthy diets, lack of sanitation, and access barriers to healthcare - all associated with human rights. Stunting has also been documented to be a major determinant of subsequent obesity and non-communicable diseases. Short leg length relative to stature during adulthood seems to be a good proxy indicator tracking such barriers, and has been reported to be associated with adverse health effects during adulthood. Our objective was to examine the association between relative leg length (as measured …

Dysphagia Screening To Prevent Hospital-Acquired Pneumonia Rates, Namneet Sekhon

Dissertations

Problem Pneumonia is a leading cause of death worldwide and affects all ages. Pneumonia may be acquired by aspiration and a bedside nursing dysphagia screen may reduce hospital acquired pneumonia (HAP) rates for stroke patients. The aim of this study was to evaluate use of the dysphagia screen for all patients receiving a computed tomography (CT) scan of the head in the emergency department (ED).

Method An observational, descriptive design for all patients who received a CT of the head in the ED and admitted over a 60-day period. The rate of dysphagia screening with the DePaul Hospital Swallow Screen …

Uab Center For Aids Research Receives $7.5 Million Grant Renewal, Alicia Rohan

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No abstract provided.

Social Behavior Change (Sbc) Business Case And Costing—Slide Deck, Breakthrough Research

Sexual and Reproductive Health, Rights, and Choices

No abstract provided.

Modulations Of Lipid Membranes Caused By Antimicrobial Agents And Helix 0 Of Endophilin, Nawal Kishore Khadka

USF Tampa Graduate Theses and Dissertations

Understanding the cellular membrane interaction with membrane active biomolecules and antimicrobial agents provides an insight in their working mechanism. Here, we studied the effect of antimicrobial agents; a recently developed peptidomimetics E107-3 and colistin as well as the N-terminal helix H0, of Endophilin A1 on the lipid bilayer.

It is important to discern the interaction mechanism of antimicrobial peptides with lipid membranes in battling multidrug resistant bacterial pathogens. We study the modification of structural and mechanical properties with a recently reported peptidomimetic on lipid bilayer. The compound referred to as E107-3 is synthesized based on the acylated reduced amide scaffold …

A Small Rna And Dna Binding Protein Contribute To Biofilm Development In Bartonella Henselae, Udoka Okaro

USF Tampa Graduate Theses and Dissertations

A biofilm, which is associated with 80% of chronic infections in humans, is formed when bacteria aggregate, attach to a substrate and secrete a matrix protecting the bacteria from host cell defenses and antibiotics. Bartonella henselae (B. henselae) is the causative agent of cat scratch disease, persistent bacteremia, and one of the most frequently reported causes of blood-culture negative endocarditis (BCNE) in patients. The ability of B. henselae to adhere to the heart valve, form a biofilm and vegetation to cause endocarditis increases the morbidity and mortality rate in infected patients. The presence of a trimeric autotransporter adhesin (TAA) called …

Bibliometric Analysis Of Research Productivity Of Health Care Professionals In Saudi Arabia: An Exploratory Study, Manuelraj Peter, Spurgeon Samuel, Mohamed Idhris, Abdurahiman Pattukuthu, Arun Vijay Subbarayalu

Library Philosophy and Practice (e-journal)

Objectives: The aim of this study is to analyze research productivity through literature mapping of Health care Professionals (HCPs) belonging to Imam Abdulrahman Bin Faisal university (IAU), Kingdom of Saudi Arabia (KSA). To facilitate that, publications made by the HCPs in those journals indexed in the PubMed indexed medical database have been chosen for this study. The selected study period was between 2014 and 2018. This study also explores the literature growth, mapping of the health care literature and health care professional’s collaboration patterns in KSA.

Methods: The chosen data were downloaded from PubMed Database through Endnote software. Publications are …

Characterization Of Bunyamwera, Batai, And Ngari Viruses: Unrecognized Arboviruses Of One Health Importance In Rwanda, Marie Fausta Dutuze

LSU Doctoral Dissertations

Bunyamwera (BUNV), Batai (BATV), and Ngari (NRIV) are mosquito-borne viruses (Genus: Orthobunyavirus, Family: Peribunyaviridae, Order: Bunyavirales). They have an RNA tripartite genome consisting of small (S), medium (M), and large (L) segments. NRIV is a natural reassortant of BUNV and BATV, with the genome: S_BUNV, M_BATV, L_BUNV. All three viruses have been associated with disease of varying severity in domestic ruminants and humans. In livestock, infection with these viruses is associated with abortions, while humans may present a mild febrile illness or severe disease such as hemorrhagic fever or meningoencephalitis. In East Africa, …